locus-tag	class	description
EGX74_RS00010	COG0457	Tetratricopeptide repeat
EGX74_RS00040	COG4886	Leucine-rich repeat (LRR) protein
EGX74_RS00050	COG3328	transposase activity
EGX74_RS00075	COG3177	Filamentation induced by cAMP protein fic
EGX74_RS00130	COG3609	addiction module antidote protein, CC2985 family
EGX74_RS00290	COG0515	serine threonine protein kinase
EGX74_RS00330	COG5599	Phosphatase
EGX74_RS00335	COG1317	bacterial-type flagellum organization
EGX74_RS00345	COG4669	(LipO)protein
EGX74_RS00380	COG1450	Type ii and iii secretion system protein
EGX74_RS00395	COG2207	Transcriptional regulator
EGX74_RS00405	COG4792	protein secretion
EGX74_RS00410	COG4791	protein targeting
EGX74_RS00415	COG4794	Type iii secretion
EGX74_RS00420	COG4790	Type iii secretion
EGX74_RS00470	COG4789	Type iii secretion
EGX74_RS00485	COG1805	sodium ion transport
EGX74_RS00500	COG3034	peptidoglycan biosynthetic process
EGX74_RS00505	COG0121	glutamine amidotransferase
EGX74_RS00515	COG1960	acyl-CoA dehydrogenase activity
EGX74_RS00525	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
EGX74_RS00550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGX74_RS00560	COG0765	amino acid transport
EGX74_RS00600	COG2814	Major facilitator Superfamily
EGX74_RS00605	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGX74_RS00615	COG1846	Transcriptional regulator
EGX74_RS00620	COG1566	PFAM secretion protein HlyD family protein
EGX74_RS00625	COG2814	Major facilitator Superfamily
EGX74_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX74_RS00635	COG3118	belongs to the thioredoxin family
EGX74_RS00640	COG3148	PFAM DTW domain containing protein
EGX74_RS00645	COG1042	CoA-binding domain protein
EGX74_RS00645	COG0045	succinate-CoA ligase (ADP-forming) activity
EGX74_RS00645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX74_RS00650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX74_RS00655	COG5544	Lipoprotein
EGX74_RS00695	COG0542	response to heat
EGX74_RS00705	COG0564	pseudouridine synthase activity
EGX74_RS00715	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX74_RS00720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGX74_RS00730	COG0077	Prephenate dehydratase
EGX74_RS00730	COG1605	Chorismate mutase
EGX74_RS00750	COG1605	Chorismate mutase
EGX74_RS00750	COG0287	Prephenate dehydrogenase
EGX74_RS00755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX74_RS00760	COG3279	Response regulator of the LytR AlgR family
EGX74_RS00770	COG3137	Salt-induced outer membrane protein
EGX74_RS00800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX74_RS00805	COG4137	Cytochrome C assembly protein
EGX74_RS00810	COG4536	flavin adenine dinucleotide binding
EGX74_RS00825	COG2918	glutathione biosynthetic process
EGX74_RS00830	COG1238	metal cluster binding
EGX74_RS00835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX74_RS00870	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EGX74_RS00915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX74_RS00920	COG3958	Transketolase
EGX74_RS00925	COG3959	Transketolase, thiamine diphosphate binding domain
EGX74_RS00930	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS00935	COG1129	ABC transporter
EGX74_RS00945	COG1879	ABC-type sugar transport system periplasmic component
EGX74_RS00955	COG3783	Cytochrome b(562)
EGX74_RS00960	COG3038	cytochrome b561
EGX74_RS00965	COG3381	protein complex oligomerization
EGX74_RS00970	COG3302	dmso reductase anchor subunit
EGX74_RS00975	COG0437	4 iron, 4 sulfur cluster binding
EGX74_RS00980	COG0243	molybdopterin cofactor binding
EGX74_RS00985	COG0235	Class ii aldolase
EGX74_RS00990	COG1349	DNA-binding transcription factor activity
EGX74_RS01005	COG1129	ABC transporter
EGX74_RS01010	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS01015	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS01020	COG3623	hexulose-6-phosphate isomerase
EGX74_RS01025	COG1070	Carbohydrate kinase
EGX74_RS01030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX74_RS01030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX74_RS01040	COG0024	Methionine aminopeptidase
EGX74_RS01050	COG4771	TonB-dependent receptor
EGX74_RS01060	COG1858	cytochrome C peroxidase
EGX74_RS01065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX74_RS01085	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX74_RS01100	COG2376	Dihydroxyacetone kinase
EGX74_RS01105	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS01110	COG1063	alcohol dehydrogenase
EGX74_RS01115	COG0698	ribose 5-phosphate isomerase
EGX74_RS01125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX74_RS01150	COG1388	LysM domain
EGX74_RS01150	COG4942	peptidase
EGX74_RS01190	COG0529	Catalyzes the synthesis of activated sulfate
EGX74_RS01245	COG0720	synthase
EGX74_RS01250	COG0602	queuosine metabolic process
EGX74_RS01270	COG3956	TIGRFAM MazG family protein
EGX74_RS01275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX74_RS01280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGX74_RS01290	COG4999	Histidine kinase
EGX74_RS01290	COG3850	Histidine kinase
EGX74_RS01290	COG3437	response regulator, receiver
EGX74_RS01290	COG2205	protein histidine kinase activity
EGX74_RS01295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX74_RS01315	COG2860	membrane
EGX74_RS01335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX74_RS01340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX74_RS01345	COG1120	ATPase activity
EGX74_RS01350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX74_RS01355	COG1643	Atp-dependent helicase
EGX74_RS01360	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGX74_RS01385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX74_RS01390	COG0617	tRNA 3'-terminal CCA addition
EGX74_RS01395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX74_RS01420	COG0842	Transport permease protein
EGX74_RS01425	COG1131	(ABC) transporter
EGX74_RS01430	COG0288	reversible hydration of carbon dioxide
EGX74_RS01435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGX74_RS01440	COG2132	Multicopper oxidase
EGX74_RS01460	COG0697	spore germination
EGX74_RS01470	COG1049	propionate catabolic process, 2-methylcitrate cycle
EGX74_RS01485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX74_RS01490	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX74_RS01495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EGX74_RS01500	COG2186	Transcriptional regulator
EGX74_RS01510	COG1113	amino acid transport
EGX74_RS01515	COG3725	Membrane protein required for beta-lactamase induction
EGX74_RS01520	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX74_RS01530	COG4969	Belongs to the N-Me-Phe pilin family
EGX74_RS01535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX74_RS01540	COG1459	type II secretion system
EGX74_RS01595	COG0582	viral genome integration into host DNA
EGX74_RS01605	COG0795	lipopolysaccharide-transporting ATPase activity
EGX74_RS01610	COG0795	lipopolysaccharide-transporting ATPase activity
EGX74_RS01620	COG2927	DNA polymerase III (CHI subunit)
EGX74_RS01625	COG0525	valine-tRNA ligase activity
EGX74_RS01635	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EGX74_RS01645	COG2731	YhcH YjgK YiaL family protein
EGX74_RS01655	COG0601	transmembrane transport
EGX74_RS01660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX74_RS01665	COG0444	Belongs to the ABC transporter superfamily
EGX74_RS01670	COG4608	Belongs to the ABC transporter superfamily
EGX74_RS01685	COG2188	Transcriptional regulator
EGX74_RS01690	COG3624	Phosphonate C-P lyase system protein PhnG
EGX74_RS01695	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EGX74_RS01700	COG3626	phosphonate metabolism
EGX74_RS01705	COG3627	carbon phosphorus lyase activity
EGX74_RS01710	COG4107	phosphonate C-P lyase system protein PhnK
EGX74_RS01715	COG4778	phosphonate C-P lyase system protein PhnL
EGX74_RS01720	COG3454	Phosphonate metabolism
EGX74_RS01725	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EGX74_RS01730	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGX74_RS01735	COG0702	epimerase
EGX74_RS01750	COG3842	ATPase activity
EGX74_RS01755	COG0395	ABC-type sugar transport system, permease component
EGX74_RS01760	COG1175	transmembrane transport
EGX74_RS01765	COG1653	transport
EGX74_RS01785	COG3153	acetyltransferase
EGX74_RS01790	COG3154	lipid carrier protein
EGX74_RS01800	COG0826	peptidase U32
EGX74_RS01805	COG0826	peptidase U32
EGX74_RS01815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX74_RS01825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX74_RS01850	COG0513	Belongs to the DEAD box helicase family
EGX74_RS01880	COG3710	Transcriptional regulator
EGX74_RS01900	COG1256	bacterial-type flagellum assembly
EGX74_RS01910	COG1706	bacterial-type flagellum-dependent cell motility
EGX74_RS01920	COG4786	Flagellar basal body rod
EGX74_RS01925	COG4787	bacterial-type flagellum-dependent cell motility
EGX74_RS01930	COG1749	Flagellar hook protein flgE
EGX74_RS01935	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGX74_RS01940	COG1558	bacterial-type flagellum-dependent cell motility
EGX74_RS01945	COG1815	bacterial-type flagellum-dependent cell motility
EGX74_RS01950	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EGX74_RS01990	COG1677	Flagellar hook-basal body complex protein FliE
EGX74_RS02015	COG1987	bacterial-type flagellum assembly
EGX74_RS02020	COG1684	flagellar biosynthetic protein fliR
EGX74_RS02025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX74_RS02045	COG4592	Periplasmic binding protein
EGX74_RS02080	COG4964	Belongs to the GSP D family
EGX74_RS02085	COG4964	Belongs to the GSP D family
EGX74_RS02140	COG0848	biopolymer transport protein
EGX74_RS02145	COG0811	peptide transport
EGX74_RS02150	COG0626	cystathionine gamma-synthase activity
EGX74_RS02155	COG0586	Pfam SNARE associated Golgi protein
EGX74_RS02160	COG2207	Transcriptional regulator
EGX74_RS02165	COG1979	alcohol dehydrogenase
EGX74_RS02175	COG0656	L-ascorbic acid biosynthetic process
EGX74_RS02190	COG2132	Multicopper oxidase
EGX74_RS02205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX74_RS02215	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGX74_RS02220	COG0583	DNA-binding transcription factor activity
EGX74_RS02230	COG3150	esterase
EGX74_RS02235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGX74_RS02240	COG3151	Protein conserved in bacteria
EGX74_RS02245	COG0494	nUDIX hydrolase
EGX74_RS02250	COG1538	Outer membrane efflux protein
EGX74_RS02265	COG0754	glutathionylspermidine amidase activity
EGX74_RS02270	COG3384	dioxygenase
EGX74_RS02290	COG0531	amino acid
EGX74_RS02305	COG3025	triphosphatase activity
EGX74_RS02310	COG4991	sh3 domain protein
EGX74_RS02325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGX74_RS02345	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EGX74_RS02350	COG0358	DNA primase activity
EGX74_RS02425	COG0251	oxidation-reduction process
EGX74_RS02445	COG0436	Aminotransferase
EGX74_RS02470	COG1289	transmembrane transporter activity
EGX74_RS02490	COG0395	ABC-type sugar transport system, permease component
EGX74_RS02500	COG2182	Extracellular solute-binding protein
EGX74_RS02505	COG1609	Transcriptional regulator
EGX74_RS02510	COG3459	Glycosyltransferase 36 associated
EGX74_RS02515	COG3842	ATPase activity
EGX74_RS02535	COG3210	domain, Protein
EGX74_RS02540	COG3210	domain, Protein
EGX74_RS02565	COG3210	domain, Protein
EGX74_RS02570	COG2831	hemolysin activation secretion protein
EGX74_RS02575	COG4245	von Willebrand factor, type A
EGX74_RS02590	COG4245	von Willebrand factor, type A
EGX74_RS02610	COG3247	response to pH
EGX74_RS02615	COG1902	pentaerythritol trinitrate reductase activity
EGX74_RS02615	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX74_RS02630	COG1451	nucleotide metabolic process
EGX74_RS02635	COG0673	inositol 2-dehydrogenase activity
EGX74_RS02660	COG2721	sulfolactate sulfo-lyase activity
EGX74_RS02675	COG2271	Major facilitator Superfamily
EGX74_RS02690	COG0586	Pfam SNARE associated Golgi protein
EGX74_RS02710	COG4575	ribosome binding
EGX74_RS02715	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EGX74_RS02725	COG2259	Doxx family
EGX74_RS02730	COG0435	Glutathione S-transferase
EGX74_RS02750	COG0494	nUDIX hydrolase
EGX74_RS02780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGX74_RS02785	COG0849	cell division
EGX74_RS02790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX74_RS02810	COG0772	Belongs to the SEDS family
EGX74_RS02825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX74_RS02830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX74_RS02835	COG0768	penicillin binding
EGX74_RS02840	COG3116	cell division
EGX74_RS02865	COG1609	Transcriptional regulator
EGX74_RS02885	COG0028	Belongs to the TPP enzyme family
EGX74_RS02895	COG1022	Amp-dependent synthetase and ligase
EGX74_RS02925	COG0473	3-isopropylmalate dehydrogenase activity
EGX74_RS02940	COG2814	Major facilitator Superfamily
EGX74_RS02955	COG4143	(ABC) transporter
EGX74_RS02960	COG1178	ABC-type Fe3 transport system permease component
EGX74_RS02965	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EGX74_RS02970	COG0586	Pfam SNARE associated Golgi protein
EGX74_RS02975	COG0417	DNA replication proofreading
EGX74_RS02995	COG3047	cAMP biosynthetic process
EGX74_RS02995	COG2885	chlorophyll binding
EGX74_RS03080	COG0564	pseudouridine synthase activity
EGX74_RS03085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EGX74_RS03135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGX74_RS03145	COG2966	Psort location CytoplasmicMembrane, score
EGX74_RS03150	COG1280	lysine exporter protein (LysE YggA)
EGX74_RS03155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGX74_RS03185	COG1047	Peptidyl-prolyl cis-trans
EGX74_RS03200	COG0196	riboflavin kinase activity
EGX74_RS03220	COG0583	DNA-binding transcription factor activity
EGX74_RS03240	COG1584	GPR1 FUN34 yaaH family protein
EGX74_RS03255	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGX74_RS03300	COG0745	RESPONSE REGULATOR receiver
EGX74_RS03305	COG3045	CreA protein
EGX74_RS03315	COG2207	Transcriptional regulator
EGX74_RS03315	COG3708	Transcriptional regulator
EGX74_RS03330	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EGX74_RS03335	COG0741	lytic transglycosylase activity
EGX74_RS03350	COG2199	diguanylate cyclase activity
EGX74_RS03355	COG2885	chlorophyll binding
EGX74_RS03380	COG0560	Phosphoserine phosphatase
EGX74_RS03385	COG3726	membrane protein affecting hemolysin expression
EGX74_RS03415	COG0084	hydrolase, TatD family'
EGX74_RS03420	COG4667	esterase of the alpha-beta hydrolase superfamily
EGX74_RS03430	COG2823	Periplasmic or secreted lipoprotein
EGX74_RS03440	COG0456	acetyltransferase
EGX74_RS03445	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EGX74_RS03490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX74_RS03495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX74_RS03510	COG0859	PFAM glycosyl transferase family 9
EGX74_RS03515	COG1070	Carbohydrate kinase
EGX74_RS03565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX74_RS03565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX74_RS03565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX74_RS03570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX74_RS03575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX74_RS03580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX74_RS03585	COG2207	Transcriptional regulator
EGX74_RS03595	COG4269	membrane
EGX74_RS03655	COG1401	restriction endodeoxyribonuclease activity
EGX74_RS03685	COG1011	Hydrolase
EGX74_RS03695	COG0174	glutamine synthetase
EGX74_RS03705	COG3852	Histidine kinase
EGX74_RS03715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX74_RS03750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX74_RS03750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX74_RS03755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX74_RS03760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EGX74_RS03765	COG3084	Protein conserved in bacteria
EGX74_RS03775	COG1763	Mo-molybdopterin cofactor biosynthetic process
EGX74_RS03780	COG3328	transposase activity
EGX74_RS03835	COG0583	DNA-binding transcription factor activity
EGX74_RS03840	COG1741	Belongs to the pirin family
EGX74_RS03850	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGX74_RS03870	COG2823	Periplasmic or secreted lipoprotein
EGX74_RS03880	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EGX74_RS03890	COG2198	Histidine kinase
EGX74_RS03890	COG0784	Response regulator, receiver
EGX74_RS03890	COG5002	protein histidine kinase activity
EGX74_RS03900	COG1242	4 iron, 4 sulfur cluster binding
EGX74_RS03905	COG0070	glutamate synthase
EGX74_RS03905	COG0069	glutamate synthase activity
EGX74_RS03905	COG0067	glutamate synthase
EGX74_RS03910	COG0493	'glutamate synthase
EGX74_RS03920	COG2969	positive regulation of protein catabolic process
EGX74_RS03925	COG0625	glutathione transferase activity
EGX74_RS03945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGX74_RS03950	COG3105	Protein conserved in bacteria
EGX74_RS03955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX74_RS03965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX74_RS03975	COG5007	Belongs to the BolA IbaG family
EGX74_RS03980	COG3113	response to antibiotic
EGX74_RS03985	COG2854	intermembrane phospholipid transfer
EGX74_RS03990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX74_RS03995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGX74_RS04000	COG1127	ABC transporter
EGX74_RS04005	COG0530	calcium, potassium:sodium antiporter activity
EGX74_RS04010	COG0517	IMP dehydrogenase activity
EGX74_RS04010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGX74_RS04015	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGX74_RS04020	COG3117	lipopolysaccharide transmembrane transporter activity
EGX74_RS04025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGX74_RS04030	COG1137	ATPase activity
EGX74_RS04035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EGX74_RS04060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX74_RS04090	COG1609	Transcriptional regulator
EGX74_RS04095	COG1263	PTS System
EGX74_RS04095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX74_RS04100	COG0366	Alpha amylase catalytic
EGX74_RS04105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX74_RS04110	COG3783	Cytochrome b(562)
EGX74_RS04125	COG0312	modulator of DNA gyrase
EGX74_RS04135	COG2732	(Barnase) inhibitor
EGX74_RS04165	COG0583	DNA-binding transcription factor activity
EGX74_RS04215	COG0312	modulator of DNA gyrase
EGX74_RS04220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX74_RS04225	COG3164	Protein of unknown function
EGX74_RS04230	COG1530	ribonuclease E activity
EGX74_RS04235	COG0424	maF-like protein
EGX74_RS04240	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGX74_RS04245	COG1792	Involved in formation and maintenance of cell shape
EGX74_RS04250	COG1077	Cell shape determining protein MreB Mrl
EGX74_RS04255	COG2200	EAL domain
EGX74_RS04255	COG2199	diguanylate cyclase activity
EGX74_RS04260	COG0604	alcohol dehydrogenase
EGX74_RS04265	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGX74_RS04280	COG0511	ligase activity, forming carbon-carbon bonds
EGX74_RS04285	COG0439	Biotin carboxylase
EGX74_RS04290	COG3924	membrane
EGX74_RS04295	COG4145	pantothenate transmembrane transporter activity
EGX74_RS04305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX74_RS04310	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGX74_RS04340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX74_RS04350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX74_RS04355	COG3133	Outer membrane lipoprotein
EGX74_RS04365	COG1278	Cold shock
EGX74_RS04370	COG1278	Cold shock
EGX74_RS04390	COG0625	glutathione transferase activity
EGX74_RS04400	COG1069	ribulokinase activity
EGX74_RS04410	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS04415	COG1129	ABC transporter
EGX74_RS04425	COG1560	Kdo2-lipid A biosynthetic process
EGX74_RS04435	COG0025	NhaP-type Na H and K H
EGX74_RS04440	COG2252	PERMEase
EGX74_RS04445	COG3077	Addiction module antitoxin, RelB DinJ family
EGX74_RS04460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX74_RS04470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX74_RS04475	COG0431	NADPH-dependent FMN reductase
EGX74_RS04480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX74_RS04485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX74_RS04490	COG1869	D-ribose catabolic process
EGX74_RS04495	COG2207	Transcriptional regulator
EGX74_RS04495	COG1917	Cupin 2, conserved barrel domain protein
EGX74_RS04500	COG0673	inositol 2-dehydrogenase activity
EGX74_RS04520	COG3209	COG3209 Rhs family protein
EGX74_RS04535	COG3501	Rhs element vgr protein
EGX74_RS04580	COG3501	Rhs element vgr protein
EGX74_RS04680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX74_RS04685	COG0058	SHG alpha-glucan phosphorylase activity
EGX74_RS04710	COG3275	phosphorelay sensor kinase activity
EGX74_RS04740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX74_RS04745	COG2095	MarC family integral membrane protein
EGX74_RS04765	COG3265	gluconokinase activity
EGX74_RS04770	COG2610	gluconate transmembrane transporter activity
EGX74_RS04775	COG1609	Transcriptional regulator
EGX74_RS04780	COG1741	Belongs to the pirin family
EGX74_RS04805	COG0191	fructose-bisphosphate aldolase activity
EGX74_RS04820	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS04835	COG2081	HI0933 family
EGX74_RS04840	COG0306	phosphate transporter
EGX74_RS04855	COG0589	response to stress
EGX74_RS04875	COG0339	signal peptide processing
EGX74_RS04880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGX74_RS04885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX74_RS04890	COG3835	regulator
EGX74_RS04900	COG2610	gluconate transmembrane transporter activity
EGX74_RS04905	COG1929	Belongs to the glycerate kinase type-1 family
EGX74_RS04930	COG1295	ribonuclease BN
EGX74_RS04935	COG2134	cdp-diacylglycerol pyrophosphatase
EGX74_RS04940	COG2982	Protein involved in outer membrane biogenesis
EGX74_RS04945	COG2200	EAL domain
EGX74_RS04950	COG1942	4-Oxalocrotonate Tautomerase
EGX74_RS04955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX74_RS04960	COG0612	Peptidase, M16
EGX74_RS04980	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGX74_RS04985	COG2200	EAL domain
EGX74_RS04985	COG2199	diguanylate cyclase activity
EGX74_RS04990	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGX74_RS04995	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGX74_RS05000	COG4608	Belongs to the ABC transporter superfamily
EGX74_RS05005	COG0444	Belongs to the ABC transporter superfamily
EGX74_RS05010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX74_RS05015	COG0601	transmembrane transport
EGX74_RS05020	COG0747	negative chemotaxis
EGX74_RS05030	COG2831	hemolysin activation secretion protein
EGX74_RS05050	COG2271	Major facilitator Superfamily
EGX74_RS05080	COG2197	response regulator
EGX74_RS05085	COG2194	sulfuric ester hydrolase activity
EGX74_RS05100	COG2986	histidine ammonia-lyase
EGX74_RS05130	COG4607	ABC-type enterochelin transport system periplasmic component
EGX74_RS05140	COG4605	iron ion homeostasis
EGX74_RS05145	COG4604	ABC transporter, ATP-binding protein
EGX74_RS05195	COG0582	viral genome integration into host DNA
EGX74_RS05200	COG2207	Transcriptional regulator
EGX74_RS05200	COG1609	Transcriptional regulator
EGX74_RS05205	COG4214	carbohydrate transport
EGX74_RS05215	COG4213	ABC transporter substrate-binding protein
EGX74_RS05225	COG1070	Carbohydrate kinase
EGX74_RS05235	COG3121	Chaperone
EGX74_RS05250	COG3274	enterobacterial common antigen metabolic process
EGX74_RS05295	COG3276	selenocysteine insertion sequence binding
EGX74_RS05310	COG2864	formate dehydrogenase
EGX74_RS05315	COG0437	4 iron, 4 sulfur cluster binding
EGX74_RS05320	COG3383	formate dehydrogenase (NAD+) activity
EGX74_RS05320	COG0243	molybdopterin cofactor binding
EGX74_RS05325	COG3383	formate dehydrogenase (NAD+) activity
EGX74_RS05325	COG0243	molybdopterin cofactor binding
EGX74_RS05335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX74_RS05360	COG3722	fumarate hydratase activity
EGX74_RS05370	COG2213	PTS system mannitol-specific
EGX74_RS05370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX74_RS05395	COG2818	Glycosylase
EGX74_RS05405	COG2885	chlorophyll binding
EGX74_RS05425	COG0366	Alpha amylase catalytic
EGX74_RS05445	COG3977	Valine--pyruvate aminotransferase
EGX74_RS05465	COG5645	(Lipo)protein
EGX74_RS05480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX74_RS05485	COG2423	ornithine cyclodeaminase activity
EGX74_RS05505	COG0561	phosphatase activity
EGX74_RS05510	COG0187	DNA topoisomerase II activity
EGX74_RS05520	COG0592	DNA-directed DNA polymerase activity
EGX74_RS05540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EGX74_RS05555	COG0706	membrane insertase activity
EGX74_RS05585	COG2252	PERMEase
EGX74_RS05595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX74_RS05600	COG0765	amino acid transport
EGX74_RS05605	COG0765	amino acid transport
EGX74_RS05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX74_RS05620	COG0704	Plays a role in the regulation of phosphate uptake
EGX74_RS05630	COG0581	inorganic phosphate transmembrane transporter activity
EGX74_RS05635	COG0573	inorganic phosphate transmembrane transporter activity
EGX74_RS05640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGX74_RS05700	COG3312	ion transport
EGX74_RS05720	COG0716	FMN binding
EGX74_RS05725	COG1522	sequence-specific DNA binding
EGX74_RS05755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX74_RS05770	COG0477	Major facilitator Superfamily
EGX74_RS05775	COG2186	Transcriptional regulator
EGX74_RS05825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGX74_RS05830	COG2224	Isocitrate lyase
EGX74_RS05860	COG0527	aspartate kinase activity
EGX74_RS05875	COG3833	ABC-type maltose transport systems, permease component
EGX74_RS05880	COG1175	transmembrane transport
EGX74_RS05945	COG1349	DNA-binding transcription factor activity
EGX74_RS05965	COG0058	SHG alpha-glucan phosphorylase activity
EGX74_RS05970	COG0058	SHG alpha-glucan phosphorylase activity
EGX74_RS05975	COG1640	4-alpha-glucanotransferase
EGX74_RS06010	COG1918	ferrous iron import across plasma membrane
EGX74_RS06015	COG2183	response to ionizing radiation
EGX74_RS06020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX74_RS06045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX74_RS06050	COG1011	Hydrolase
EGX74_RS06060	COG0494	nUDIX hydrolase
EGX74_RS06065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EGX74_RS06095	COG4796	Type ii and iii secretion system protein
EGX74_RS06120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX74_RS06125	COG0546	phosphoglycolate phosphatase activity
EGX74_RS06130	COG0180	Tryptophanyl-tRNA synthetase
EGX74_RS06150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX74_RS06155	COG0402	S-adenosylhomocysteine deaminase activity
EGX74_RS06175	COG1486	melibiose metabolic process
EGX74_RS06180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX74_RS06185	COG0433	COG0433 Predicted ATPase
EGX74_RS06200	COG1289	transmembrane transporter activity
EGX74_RS06210	COG1765	OsmC-like protein
EGX74_RS06220	COG3954	Phosphoribulokinase
EGX74_RS06230	COG0429	hydrolase of the alpha beta-hydrolase fold
EGX74_RS06240	COG4521	taurine ABC transporter
EGX74_RS06250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX74_RS06255	COG2175	clavaminate synthase activity
EGX74_RS06265	COG1216	Glycosyl transferase, family 2
EGX74_RS06285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGX74_RS06290	COG1047	Peptidyl-prolyl cis-trans
EGX74_RS06305	COG0545	Peptidyl-prolyl cis-trans isomerase
EGX74_RS06310	COG2964	Protein conserved in bacteria
EGX74_RS06330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGX74_RS06335	COG0049	tRNA binding
EGX74_RS06375	COG0051	transcription antitermination factor activity, RNA binding
EGX74_RS06390	COG0089	rRNA binding
EGX74_RS06400	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGX74_RS06410	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGX74_RS06415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGX74_RS06425	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGX74_RS06430	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGX74_RS06470	COG1841	ribosomal large subunit assembly
EGX74_RS06480	COG0201	protein transport
EGX74_RS06485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX74_RS06500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGX74_RS06515	COG0789	Transcriptional regulator
EGX74_RS06520	COG3036	rescue of stalled ribosome
EGX74_RS06550	COG0758	DNA mediated transformation
EGX74_RS06560	COG0551	DNA topoisomerase type I activity
EGX74_RS06575	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGX74_RS06595	COG0456	acetyltransferase
EGX74_RS06600	COG2982	Protein involved in outer membrane biogenesis
EGX74_RS06605	COG2233	PERMEase
EGX74_RS06610	COG0786	glutamate:sodium symporter activity
EGX74_RS06620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX74_RS06625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX74_RS06630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX74_RS06650	COG2860	membrane
EGX74_RS06655	COG1561	YicC-like family, N-terminal region
EGX74_RS06680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX74_RS06725	COG1519	Transferase
EGX74_RS06730	COG0859	PFAM glycosyl transferase family 9
EGX74_RS06735	COG0859	PFAM glycosyl transferase family 9
EGX74_RS06745	COG0156	8-amino-7-oxononanoate synthase activity
EGX74_RS06760	COG4942	peptidase
EGX74_RS06770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX74_RS06775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX74_RS06795	COG1045	serine acetyltransferase
EGX74_RS06800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGX74_RS06805	COG2169	Transcriptional regulator
EGX74_RS06805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX74_RS06810	COG2205	protein histidine kinase activity
EGX74_RS06815	COG0745	RESPONSE REGULATOR receiver
EGX74_RS06820	COG3678	ATP-independent chaperone mediated protein folding
EGX74_RS06850	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGX74_RS06860	COG0471	metal ion transport
EGX74_RS06865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGX74_RS06870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGX74_RS06875	COG0583	DNA-binding transcription factor activity
EGX74_RS06890	COG3152	Membrane
EGX74_RS06900	COG1494	fructose-1,6-bisphosphatase
EGX74_RS06905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX74_RS06910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX74_RS06970	COG1575	Belongs to the MenA family. Type 1 subfamily
EGX74_RS06985	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX74_RS06990	COG1609	Transcriptional regulator
EGX74_RS07000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX74_RS07010	COG4682	membrane
EGX74_RS07025	COG0460	homoserine dehydrogenase
EGX74_RS07025	COG0527	aspartate kinase activity
EGX74_RS07065	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGX74_RS07080	COG1629	transport
EGX74_RS07105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX74_RS07110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX74_RS07110	COG0678	peroxiredoxin activity
EGX74_RS07190	COG1879	ABC-type sugar transport system periplasmic component
EGX74_RS07195	COG1129	ABC transporter
EGX74_RS07200	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS07205	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS07215	COG3085	chromosome segregation
EGX74_RS07240	COG3978	acetolactate synthase activity
EGX74_RS07245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX74_RS07290	COG0583	DNA-binding transcription factor activity
EGX74_RS07330	COG3121	Chaperone
EGX74_RS07345	COG3121	Chaperone
EGX74_RS07360	COG3328	transposase activity
EGX74_RS07370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX74_RS07395	COG3118	belongs to the thioredoxin family
EGX74_RS07400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGX74_RS07405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX74_RS07410	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGX74_RS07415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGX74_RS07420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGX74_RS07425	COG1088	dTDP-glucose 4,6-dehydratase activity
EGX74_RS07430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGX74_RS07435	COG0456	acetyltransferase
EGX74_RS07440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGX74_RS07445	COG2244	polysaccharide biosynthetic process
EGX74_RS07465	COG1113	amino acid transport
EGX74_RS07505	COG3071	HemY protein
EGX74_RS07510	COG2959	enzyme of heme biosynthesis
EGX74_RS07515	COG1587	Uroporphyrinogen-III synthase
EGX74_RS07530	COG3072	Adenylate cyclase
EGX74_RS07550	COG3159	Protein conserved in bacteria
EGX74_RS07555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGX74_RS07560	COG1011	Hydrolase
EGX74_RS07565	COG0210	DNA helicase
EGX74_RS07575	COG5441	Belongs to the UPF0261 family
EGX74_RS07580	COG5564	TIM-barrel signal transduction protein
EGX74_RS07595	COG2050	protein possibly involved in aromatic compounds catabolism
EGX74_RS07605	COG0514	ATP-dependent DNA helicase (RecQ)
EGX74_RS07610	COG1280	lysine exporter protein (LysE YggA)
EGX74_RS07615	COG1280	lysine exporter protein (LysE YggA)
EGX74_RS07620	COG2267	carboxylic ester hydrolase activity
EGX74_RS07625	COG0561	phosphatase activity
EGX74_RS07635	COG0584	glycerophosphoryl diester phosphodiesterase
EGX74_RS07650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX74_RS07660	COG0247	lactate metabolic process
EGX74_RS07670	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGX74_RS07685	COG3714	YhhN family
EGX74_RS07700	COG3776	membrane
EGX74_RS07705	COG0742	ribosomal rna small subunit methyltransferase
EGX74_RS07715	COG0552	protein localization to endoplasmic reticulum
EGX74_RS07715	COG0552	protein localization to endoplasmic reticulum
EGX74_RS07720	COG2884	Cell division ATP-binding protein ftsE
EGX74_RS07725	COG2177	Part of the ABC transporter FtsEX involved in
EGX74_RS07745	COG0683	leucine binding
EGX74_RS07755	COG4177	L-phenylalanine transmembrane transporter activity
EGX74_RS07765	COG0410	ABC transporter
EGX74_RS07825	COG0584	glycerophosphoryl diester phosphodiesterase
EGX74_RS07830	COG0679	Auxin Efflux Carrier
EGX74_RS07835	COG0697	spore germination
EGX74_RS07840	COG0583	DNA-binding transcription factor activity
EGX74_RS07850	COG0412	Dienelactone hydrolase
EGX74_RS07865	COG1966	Carbon starvation protein
EGX74_RS07870	COG0586	Pfam SNARE associated Golgi protein
EGX74_RS07875	COG1322	Protein conserved in bacteria
EGX74_RS07895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX74_RS07905	COG0805	protein transport
EGX74_RS07940	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EGX74_RS07965	COG1739	Uncharacterized protein family UPF0029
EGX74_RS07980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX74_RS07985	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EGX74_RS08020	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGX74_RS08085	COG0250	Participates in transcription elongation, termination and antitermination
EGX74_RS08145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX74_RS08180	COG1515	deoxyribonuclease V activity
EGX74_RS08200	COG0151	Belongs to the GarS family
EGX74_RS08270	COG4771	TonB-dependent receptor
EGX74_RS08275	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX74_RS08280	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EGX74_RS08335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX74_RS08345	COG5001	Diguanylate cyclase
EGX74_RS08375	COG0195	Participates in both transcription termination and antitermination
EGX74_RS08395	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX74_RS08405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGX74_RS08430	COG1534	Rna-binding protein
EGX74_RS08440	COG2027	D-alanyl-D-alanine carboxypeptidase
EGX74_RS08445	COG0745	RESPONSE REGULATOR receiver
EGX74_RS08450	COG0642	Histidine kinase
EGX74_RS08460	COG0697	spore germination
EGX74_RS08475	COG0142	geranyltranstransferase activity
EGX74_RS08485	COG3423	Transcriptional regulator
EGX74_RS08510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX74_RS08515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EGX74_RS08520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGX74_RS08525	COG2105	PFAM AIG2 family protein
EGX74_RS08530	COG2911	Protein conserved in bacteria
EGX74_RS08535	COG0729	surface antigen
EGX74_RS08545	COG1253	flavin adenine dinucleotide binding
EGX74_RS08555	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EGX74_RS08565	COG0737	Belongs to the 5'-nucleotidase family
EGX74_RS08575	COG0545	Peptidyl-prolyl cis-trans isomerase
EGX74_RS08580	COG3061	Opacity-associated protein A
EGX74_RS08600	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGX74_RS08610	COG0360	Binds together with S18 to 16S ribosomal RNA
EGX74_RS08620	COG1073	alpha beta
EGX74_RS08645	COG3650	response to hydrogen peroxide
EGX74_RS08650	COG1960	acyl-CoA dehydrogenase activity
EGX74_RS08655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX74_RS08660	COG0557	exoribonuclease II activity
EGX74_RS08675	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EGX74_RS08680	COG0330	HflC and HflK could
EGX74_RS08685	COG0330	HflC and HflK could
EGX74_RS08690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX74_RS08710	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX74_RS08715	COG0802	atpase or kinase
EGX74_RS08720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGX74_RS08720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX74_RS08725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX74_RS08745	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGX74_RS08765	COG1511	domain protein
EGX74_RS08765	COG3264	Mechanosensitive ion channel
EGX74_RS08780	COG1053	succinate dehydrogenase
EGX74_RS08785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGX74_RS08795	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EGX74_RS08845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGX74_RS08860	COG3383	formate dehydrogenase (NAD+) activity
EGX74_RS08865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX74_RS08870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX74_RS08870	COG0493	'glutamate synthase
EGX74_RS08880	COG1309	transcriptional regulator
EGX74_RS08950	COG1454	alcohol dehydrogenase
EGX74_RS08960	COG0629	single-stranded DNA binding
EGX74_RS08965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX74_RS08970	COG2315	Protein conserved in bacteria
EGX74_RS08975	COG1448	Aminotransferase
EGX74_RS09000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX74_RS09005	COG0735	belongs to the Fur family
EGX74_RS09015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGX74_RS09070	COG3121	Chaperone
EGX74_RS09130	COG1358	cellular component organization or biogenesis
EGX74_RS09155	COG3721	Heme iron utilization protein
EGX74_RS09160	COG0702	epimerase
EGX74_RS09170	COG4771	TonB-dependent receptor
EGX74_RS09175	COG3720	iron ion transport
EGX74_RS09180	COG4558	Periplasmic binding protein
EGX74_RS09185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX74_RS09195	COG0626	cystathionine gamma-synthase activity
EGX74_RS09200	COG0814	amino acid
EGX74_RS09205	COG0583	DNA-binding transcription factor activity
EGX74_RS09210	COG0425	Belongs to the sulfur carrier protein TusA family
EGX74_RS09215	COG2391	methyltransferase activity
EGX74_RS09335	COG3162	membrane
EGX74_RS09365	COG2226	methyltransferase
EGX74_RS09365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX74_RS09365	COG3433	isochorismatase activity
EGX74_RS09375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX74_RS09375	COG3433	isochorismatase activity
EGX74_RS09375	COG2226	methyltransferase
EGX74_RS09400	COG1132	(ABC) transporter
EGX74_RS09400	COG2375	cellular response to nickel ion
EGX74_RS09405	COG1132	(ABC) transporter
EGX74_RS09420	COG2610	gluconate transmembrane transporter activity
EGX74_RS09435	COG3501	Rhs element vgr protein
EGX74_RS09465	COG0471	metal ion transport
EGX74_RS09485	COG2211	Major facilitator Superfamily
EGX74_RS09535	COG2771	luxR family
EGX74_RS09540	COG3916	Acyl-homoserine-lactone synthase
EGX74_RS09670	COG1982	Orn Lys Arg decarboxylase major
EGX74_RS09675	COG1879	ABC-type sugar transport system periplasmic component
EGX74_RS09680	COG1129	ABC transporter
EGX74_RS09685	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS09690	COG4774	siderophore transport
EGX74_RS09715	COG1194	a g-specific adenine glycosylase
EGX74_RS09725	COG3171	Protein conserved in bacteria
EGX74_RS09740	COG3064	Membrane
EGX74_RS09740	COG1073	alpha beta
EGX74_RS09740	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EGX74_RS09745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX74_RS09750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGX74_RS09760	COG0762	integral membrane protein
EGX74_RS09770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGX74_RS09775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGX74_RS09780	COG2805	Type II/IV secretion system protein
EGX74_RS09790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX74_RS09805	COG0189	ligase activity
EGX74_RS09810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX74_RS09815	COG2356	endonuclease I
EGX74_RS09830	COG1166	arginine decarboxylase activity
EGX74_RS09845	COG0501	Belongs to the peptidase M48B family
EGX74_RS09855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGX74_RS09875	COG0191	fructose-bisphosphate aldolase activity
EGX74_RS09910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGX74_RS09915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGX74_RS09940	COG0006	proline dipeptidase activity
EGX74_RS09945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX74_RS09950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX74_RS09990	COG5295	Hep Hag repeat protein
EGX74_RS10000	COG1272	protein, Hemolysin III
EGX74_RS10025	COG0745	RESPONSE REGULATOR receiver
EGX74_RS10030	COG2205	protein histidine kinase activity
EGX74_RS10035	COG4452	Inner membrane protein CreD
EGX74_RS10040	COG0716	FMN binding
EGX74_RS10045	COG4974	Belongs to the 'phage' integrase family
EGX74_RS10050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX74_RS10055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX74_RS10075	COG0582	viral genome integration into host DNA
EGX74_RS10100	COG2944	sequence-specific DNA binding
EGX74_RS10190	COG1695	Transcriptional regulator
EGX74_RS10195	COG0791	NLP P60 protein
EGX74_RS10205	COG1879	ABC-type sugar transport system periplasmic component
EGX74_RS10210	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS10215	COG1129	ABC transporter
EGX74_RS10225	COG2182	Extracellular solute-binding protein
EGX74_RS10230	COG1175	transmembrane transport
EGX74_RS10235	COG3833	ABC-type maltose transport systems, permease component
EGX74_RS10240	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EGX74_RS10245	COG1874	Beta-galactosidase
EGX74_RS10250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX74_RS10250	COG1263	PTS System
EGX74_RS10270	COG2271	Major facilitator Superfamily
EGX74_RS10300	COG3119	arylsulfatase activity
EGX74_RS10305	COG0641	radical SAM
EGX74_RS10315	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS10325	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX74_RS10330	COG3716	PTS system mannose fructose sorbose family IID component
EGX74_RS10335	COG3715	PTS system
EGX74_RS10340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX74_RS10345	COG2222	sugar isomerase
EGX74_RS10355	COG1349	DNA-binding transcription factor activity
EGX74_RS10360	COG3119	arylsulfatase activity
EGX74_RS10410	COG0288	reversible hydration of carbon dioxide
EGX74_RS10435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX74_RS10460	COG2165	general secretion pathway protein
EGX74_RS10505	COG0840	transmembrane signaling receptor activity
EGX74_RS10520	COG0583	DNA-binding transcription factor activity
EGX74_RS10525	COG2814	Major facilitator Superfamily
EGX74_RS10530	COG0583	DNA-binding transcription factor activity
EGX74_RS10540	COG1609	Transcriptional regulator
EGX74_RS10570	COG0667	Aldo Keto reductase
EGX74_RS10640	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGX74_RS10650	COG1074	ATP-dependent DNA helicase activity
EGX74_RS10655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX74_RS10665	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX74_RS10680	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EGX74_RS10685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX74_RS10690	COG2166	iron-sulfur cluster assembly
EGX74_RS10695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGX74_RS10705	COG0583	DNA-binding transcription factor activity
EGX74_RS10710	COG2363	Small membrane protein
EGX74_RS10730	COG1611	Belongs to the LOG family
EGX74_RS10750	COG3098	single-species biofilm formation
EGX74_RS10755	COG0564	pseudouridine synthase activity
EGX74_RS10825	COG0575	Belongs to the CDS family
EGX74_RS10830	COG0750	zinc metalloprotease
EGX74_RS10845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGX74_RS10870	COG0587	DNA-directed DNA polymerase activity
EGX74_RS10880	COG0346	lactoylglutathione lyase activity
EGX74_RS10885	COG0037	tRNA processing
EGX74_RS10895	COG4568	rho-dependent transcription termination
EGX74_RS10905	COG4681	YaeQ
EGX74_RS10915	COG3015	lipoprotein NlpE involved in copper resistance
EGX74_RS10925	COG1720	tRNA m6t6A37 methyltransferase activity
EGX74_RS10935	COG1464	Belongs to the NlpA lipoprotein family
EGX74_RS10940	COG2011	ABC-type metal ion transport system permease component
EGX74_RS10950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGX74_RS10985	COG0656	L-ascorbic acid biosynthetic process
EGX74_RS11005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX74_RS11010	COG2226	methyltransferase
EGX74_RS11030	COG1953	Uracil, thiamine, allantoin
EGX74_RS11055	COG3657	addiction module killer protein
EGX74_RS11115	COG0582	viral genome integration into host DNA
EGX74_RS11145	COG2867	negative regulation of translational initiation
EGX74_RS11155	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX74_RS11160	COG0497	DNA recombination
EGX74_RS11165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGX74_RS11180	COG2009	succinate dehydrogenase
EGX74_RS11185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGX74_RS11190	COG1053	succinate dehydrogenase
EGX74_RS11200	COG0567	Dehydrogenase, E1 component
EGX74_RS11205	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX74_RS11215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGX74_RS11220	COG1271	oxidase subunit
EGX74_RS11225	COG1294	oxidase, subunit
EGX74_RS11230	COG4890	Cyd operon protein YbgT
EGX74_RS11235	COG3790	cyd operon protein YbgE
EGX74_RS11240	COG0824	Thioesterase
EGX74_RS11245	COG0811	peptide transport
EGX74_RS11250	COG0848	biopolymer transport protein
EGX74_RS11255	COG3064	Membrane
EGX74_RS11255	COG3064	Membrane
EGX74_RS11265	COG2885	chlorophyll binding
EGX74_RS11270	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EGX74_RS11300	COG1230	cation diffusion facilitator family transporter
EGX74_RS11305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX74_RS11320	COG2017	converts alpha-aldose to the beta-anomer
EGX74_RS11335	COG1085	galactose-1-phosphate uridylyltransferase
EGX74_RS11340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGX74_RS11350	COG1119	ATPase activity
EGX74_RS11360	COG2005	Transcriptional regulator
EGX74_RS11360	COG3585	molybdate ion transport
EGX74_RS11370	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGX74_RS11375	COG4149	molybdate abc transporter
EGX74_RS11385	COG0561	phosphatase activity
EGX74_RS11410	COG2226	methyltransferase
EGX74_RS11420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGX74_RS11430	COG4628	conserved protein (DUF2132)
EGX74_RS11435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EGX74_RS11440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGX74_RS11450	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EGX74_RS11455	COG0314	molybdopterin synthase activity
EGX74_RS11460	COG0670	Belongs to the BI1 family
EGX74_RS11485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX74_RS11490	COG0583	DNA-binding transcription factor activity
EGX74_RS11500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGX74_RS11505	COG2211	Major facilitator Superfamily
EGX74_RS11535	COG1902	pentaerythritol trinitrate reductase activity
EGX74_RS11555	COG0842	Transport permease protein
EGX74_RS11560	COG0842	Transport permease protein
EGX74_RS11565	COG1131	(ABC) transporter
EGX74_RS11575	COG1309	transcriptional regulator
EGX74_RS11580	COG0513	Belongs to the DEAD box helicase family
EGX74_RS11615	COG3328	transposase activity
EGX74_RS11640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX74_RS11650	COG1686	Belongs to the peptidase S11 family
EGX74_RS11655	COG0277	FAD linked oxidase domain protein
EGX74_RS11675	COG2261	transglycosylase associated protein
EGX74_RS11685	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EGX74_RS11700	COG4807	Protein conserved in bacteria
EGX74_RS11720	COG1122	ATPase activity
EGX74_RS11740	COG2897	thiosulfate sulfurtransferase activity
EGX74_RS11745	COG1732	Glycine betaine
EGX74_RS11750	COG1732	Glycine betaine
EGX74_RS11755	COG1174	glycine betaine transport
EGX74_RS11760	COG1125	glycine betaine transport
EGX74_RS11765	COG1174	glycine betaine transport
EGX74_RS11770	COG0531	amino acid
EGX74_RS11775	COG1982	Orn Lys Arg decarboxylase major
EGX74_RS11785	COG0697	spore germination
EGX74_RS11815	COG0814	amino acid
EGX74_RS11835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX74_RS11860	COG2205	protein histidine kinase activity
EGX74_RS11860	COG0784	Response regulator, receiver
EGX74_RS11870	COG2198	Histidine kinase
EGX74_RS11870	COG0642	Histidine kinase
EGX74_RS11875	COG2198	Histidine kinase
EGX74_RS11875	COG0642	Histidine kinase
EGX74_RS11880	COG2223	nitrite transmembrane transporter activity
EGX74_RS11915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGX74_RS11960	COG3395	kinase activity
EGX74_RS11965	COG0235	Class ii aldolase
EGX74_RS11970	COG1349	DNA-binding transcription factor activity
EGX74_RS11975	COG3622	Belongs to the hyi family
EGX74_RS11995	COG4386	tail sheath protein
EGX74_RS12035	COG3299	homolog of phage Mu protein gp47
EGX74_RS12055	COG1737	Transcriptional regulator
EGX74_RS12060	COG2723	6-phospho-beta-galactosidase activity
EGX74_RS12075	COG3157	Type VI secretion system effector, Hcp
EGX74_RS12095	COG3083	sulfuric ester hydrolase activity
EGX74_RS12100	COG3082	Protein of unknown function (DUF1414)
EGX74_RS12125	COG1061	Type III restriction enzyme res subunit
EGX74_RS12130	COG1187	pseudouridine synthase activity
EGX74_RS12135	COG2814	Major facilitator Superfamily
EGX74_RS12145	COG4172	Belongs to the ABC transporter superfamily
EGX74_RS12150	COG4239	(ABC) transporter, permease
EGX74_RS12155	COG4174	ABC transporter (Permease)
EGX74_RS12160	COG4166	transmembrane transport
EGX74_RS12165	COG2200	EAL domain
EGX74_RS12170	COG0791	NLP P60 protein
EGX74_RS12175	COG0671	phosphoesterase, PA-phosphatase related
EGX74_RS12180	COG0523	cobalamin synthesis protein
EGX74_RS12190	COG2186	Transcriptional regulator
EGX74_RS12195	COG0246	Mannitol dehydrogenase
EGX74_RS12220	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS12255	COG1129	ABC transporter
EGX74_RS12265	COG0494	nUDIX hydrolase
EGX74_RS12275	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX74_RS12280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX74_RS12280	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGX74_RS12280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX74_RS12285	COG3710	Transcriptional regulator
EGX74_RS12300	COG3121	Chaperone
EGX74_RS12305	COG3188	usher protein
EGX74_RS12315	COG2855	membrane
EGX74_RS12320	COG0583	DNA-binding transcription factor activity
EGX74_RS12325	COG0833	amino acid
EGX74_RS12335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX74_RS12345	COG4771	TonB-dependent receptor
EGX74_RS12355	COG0625	glutathione transferase activity
EGX74_RS12380	COG2011	ABC-type metal ion transport system permease component
EGX74_RS12385	COG1686	Belongs to the peptidase S11 family
EGX74_RS12390	COG0814	amino acid
EGX74_RS12395	COG1349	DNA-binding transcription factor activity
EGX74_RS12405	COG0671	phosphoesterase, PA-phosphatase related
EGX74_RS12440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGX74_RS12445	COG3842	ATPase activity
EGX74_RS12450	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX74_RS12455	COG1177	transmembrane transport
EGX74_RS12470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX74_RS12495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX74_RS12500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX74_RS12505	COG1120	ATPase activity
EGX74_RS12525	COG4160	amino acid transport
EGX74_RS12530	COG4215	(ABC) transporter
EGX74_RS12535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX74_RS12540	COG1126	abc transporter atp-binding protein
EGX74_RS12545	COG1605	Chorismate mutase
EGX74_RS12555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX74_RS12560	COG0702	epimerase
EGX74_RS12565	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EGX74_RS12575	COG0028	Belongs to the TPP enzyme family
EGX74_RS12580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX74_RS12590	COG2431	L-lysine efflux transmembrane transporter activity
EGX74_RS12595	COG3593	DNA synthesis involved in DNA repair
EGX74_RS12600	COG2990	Protein conserved in bacteria
EGX74_RS12605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX74_RS12625	COG1278	Cold shock
EGX74_RS12640	COG0542	response to heat
EGX74_RS12655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGX74_RS12665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGX74_RS12675	COG0492	ferredoxin-NADP+ reductase activity
EGX74_RS12685	COG1674	ftsk spoiiie
EGX74_RS12685	COG3107	peptidoglycan biosynthetic process
EGX74_RS12695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGX74_RS12725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGX74_RS12735	COG1882	Formate acetyltransferase
EGX74_RS12740	COG2116	formate transmembrane transporter activity
EGX74_RS12745	COG1944	ATP diphosphatase activity
EGX74_RS12750	COG0252	asparaginase activity
EGX74_RS12755	COG5295	Hep Hag repeat protein
EGX74_RS12755	COG5295	Hep Hag repeat protein
EGX74_RS12780	COG0539	negative regulation of cytoplasmic translation
EGX74_RS12795	COG0658	competence protein
EGX74_RS12795	COG2333	competence protein COMEC
EGX74_RS12810	COG5383	Protein conserved in bacteria
EGX74_RS12820	COG1278	Cold shock
EGX74_RS12840	COG3173	Aminoglycoside phosphotransferase
EGX74_RS12855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGX74_RS12885	COG2989	Protein conserved in bacteria
EGX74_RS12890	COG3108	Peptidase M15
EGX74_RS12895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX74_RS12905	COG1448	Aminotransferase
EGX74_RS12925	COG0308	aminopeptidase N
EGX74_RS12940	COG3217	Mosc domain protein beta barrel domain protein
EGX74_RS12940	COG0633	Ferredoxin
EGX74_RS12950	COG0488	(ABC) transporter
EGX74_RS12955	COG2995	paraquat-inducible protein a
EGX74_RS12960	COG3008	intermembrane lipid transfer
EGX74_RS12960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX74_RS12965	COG3009	Protein conserved in bacteria
EGX74_RS12975	COG3130	regulation of translation
EGX74_RS13005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX74_RS13020	COG1067	ATP-dependent peptidase activity
EGX74_RS13045	COG3070	regulator of competence-specific genes
EGX74_RS13050	COG1289	transmembrane transporter activity
EGX74_RS13055	COG3304	Inner membrane component domain
EGX74_RS13060	COG0210	DNA helicase
EGX74_RS13075	COG1832	CoA-binding protein
EGX74_RS13095	COG2920	part of a sulfur-relay system
EGX74_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS13130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGX74_RS13135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX74_RS13140	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS13145	COG3425	synthase
EGX74_RS13155	COG1024	Enoyl-CoA hydratase
EGX74_RS13160	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS13170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX74_RS13175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGX74_RS13305	COG0488	(ABC) transporter
EGX74_RS13315	COG3328	transposase activity
EGX74_RS13325	COG0303	'Molybdopterin
EGX74_RS13335	COG1136	(ABC) transporter
EGX74_RS13365	COG0583	DNA-binding transcription factor activity
EGX74_RS13370	COG0477	Major facilitator Superfamily
EGX74_RS13380	COG2311	Membrane
EGX74_RS13395	COG4211	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS13400	COG2949	membrane
EGX74_RS13415	COG1346	cytolysis
EGX74_RS13425	COG2814	Major facilitator Superfamily
EGX74_RS13460	COG0489	protein tyrosine kinase activity
EGX74_RS13475	COG2982	Protein involved in outer membrane biogenesis
EGX74_RS13480	COG1253	flavin adenine dinucleotide binding
EGX74_RS13485	COG4114	ferric iron reductase
EGX74_RS13490	COG0076	glutamate decarboxylase activity
EGX74_RS13495	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EGX74_RS13510	COG1120	ATPase activity
EGX74_RS13515	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX74_RS13520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX74_RS13525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX74_RS13540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX74_RS13545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX74_RS13555	COG0140	phosphoribosyl-ATP diphosphatase activity
EGX74_RS13555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGX74_RS13575	COG0131	Imidazoleglycerol-phosphate dehydratase
EGX74_RS13575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGX74_RS13585	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGX74_RS13600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX74_RS13605	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS13610	COG1129	ABC transporter
EGX74_RS13615	COG1129	ABC transporter
EGX74_RS13620	COG0371	Dehydrogenase
EGX74_RS13630	COG0531	amino acid
EGX74_RS13640	COG2925	Exonuclease
EGX74_RS13655	COG3328	transposase activity
EGX74_RS13660	COG1388	LysM domain
EGX74_RS13660	COG1470	cell adhesion involved in biofilm formation
EGX74_RS13665	COG2271	Major facilitator Superfamily
EGX74_RS13670	COG3011	Protein conserved in bacteria
EGX74_RS13675	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS13685	COG4948	Mandelate Racemase Muconate Lactonizing
EGX74_RS13705	COG0534	Mate efflux family protein
EGX74_RS13725	COG3122	Protein conserved in bacteria
EGX74_RS13750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGX74_RS13770	COG2223	nitrite transmembrane transporter activity
EGX74_RS13775	COG3328	transposase activity
EGX74_RS13830	COG1132	(ABC) transporter
EGX74_RS13845	COG2207	Transcriptional regulator
EGX74_RS13885	COG1113	amino acid transport
EGX74_RS13910	COG1496	oxidoreductase activity
EGX74_RS13915	COG2226	methyltransferase
EGX74_RS13945	COG3716	PTS system mannose fructose sorbose family IID component
EGX74_RS13950	COG3715	PTS system
EGX74_RS13955	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX74_RS13955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX74_RS13960	COG1253	flavin adenine dinucleotide binding
EGX74_RS13970	COG1846	Transcriptional regulator
EGX74_RS13985	COG1012	belongs to the aldehyde dehydrogenase family
EGX74_RS13990	COG3384	dioxygenase
EGX74_RS14000	COG3971	2-oxopent-4-enoate hydratase activity
EGX74_RS14015	COG2368	4-hydroxyphenylacetate
EGX74_RS14020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX74_RS14025	COG1760	l-serine dehydratase
EGX74_RS14050	COG0513	Belongs to the DEAD box helicase family
EGX74_RS14055	COG3141	response to X-ray
EGX74_RS14070	COG1770	oligopeptidase
EGX74_RS14085	COG1528	Iron-storage protein
EGX74_RS14090	COG2372	response to copper ion
EGX74_RS14125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX74_RS14130	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX74_RS14155	COG3418	PFAM FlgN family protein
EGX74_RS14160	COG2747	anti-sigma28 factor FlgM
EGX74_RS14170	COG1815	bacterial-type flagellum-dependent cell motility
EGX74_RS14175	COG1558	bacterial-type flagellum-dependent cell motility
EGX74_RS14215	COG1256	bacterial-type flagellum assembly
EGX74_RS14225	COG2390	Transcriptional regulator
EGX74_RS14230	COG3347	Dehydrogenase
EGX74_RS14230	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS14235	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS14245	COG1129	ABC transporter
EGX74_RS14250	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS14255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX74_RS14275	COG1987	bacterial-type flagellum assembly
EGX74_RS14300	COG1580	Controls the rotational direction of flagella during chemotaxis
EGX74_RS14315	COG1157	protein secretion by the type III secretion system
EGX74_RS14335	COG1677	Flagellar hook-basal body complex protein FliE
EGX74_RS14355	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EGX74_RS14360	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EGX74_RS14365	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EGX74_RS14400	COG1191	sigma factor activity
EGX74_RS14415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX74_RS14420	COG0765	amino acid transport
EGX74_RS14425	COG1126	abc transporter atp-binding protein
EGX74_RS14440	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX74_RS14440	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX74_RS14440	COG0506	proline dehydrogenase activity
EGX74_RS14455	COG0672	)-iron permease
EGX74_RS14460	COG2822	iron ion transport
EGX74_RS14480	COG1113	amino acid transport
EGX74_RS14505	COG3136	membrane protein required for alginate biosynthesis
EGX74_RS14515	COG2197	response regulator
EGX74_RS14660	COG2188	Transcriptional regulator
EGX74_RS14670	COG0673	inositol 2-dehydrogenase activity
EGX74_RS14680	COG1175	transmembrane transport
EGX74_RS14685	COG0395	ABC-type sugar transport system, permease component
EGX74_RS14690	COG3842	ATPase activity
EGX74_RS14765	COG4771	TonB-dependent receptor
EGX74_RS14770	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGX74_RS14790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX74_RS14790	COG3433	isochorismatase activity
EGX74_RS14790	COG2226	methyltransferase
EGX74_RS14805	COG1132	(ABC) transporter
EGX74_RS14810	COG2814	Major facilitator Superfamily
EGX74_RS14815	COG1169	isochorismate synthase
EGX74_RS14820	COG0582	viral genome integration into host DNA
EGX74_RS14830	COG3121	Chaperone
EGX74_RS14840	COG3188	usher protein
EGX74_RS14855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX74_RS14855	COG2205	protein histidine kinase activity
EGX74_RS14865	COG0427	acetyl-CoA hydrolase
EGX74_RS14870	COG2030	dehydratase
EGX74_RS14895	COG2814	Major facilitator Superfamily
EGX74_RS14910	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX74_RS14915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX74_RS14925	COG1349	DNA-binding transcription factor activity
EGX74_RS14935	COG2066	Belongs to the glutaminase family
EGX74_RS14945	COG0672	)-iron permease
EGX74_RS14970	COG0577	efflux transmembrane transporter activity
EGX74_RS14970	COG1136	(ABC) transporter
EGX74_RS14990	COG0006	proline dipeptidase activity
EGX74_RS14995	COG0457	Tetratricopeptide repeat
EGX74_RS15000	COG0726	polysaccharide deacetylase
EGX74_RS15000	COG1649	PFAM Uncharacterised BCR, COG1649
EGX74_RS15005	COG1215	transferase activity, transferring glycosyl groups
EGX74_RS15010	COG3658	cytochrome
EGX74_RS15025	COG1702	phosphate starvation-inducible protein PhoH
EGX74_RS15035	COG0387	Pfam Sodium calcium exchanger
EGX74_RS15040	COG3850	Histidine kinase
EGX74_RS15050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX74_RS15115	COG0402	S-adenosylhomocysteine deaminase activity
EGX74_RS15135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX74_RS15205	COG0500	methyltransferase
EGX74_RS15245	COG5002	protein histidine kinase activity
EGX74_RS15300	COG0012	GTP binding
EGX74_RS15315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX74_RS15340	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX74_RS15360	COG0659	secondary active sulfate transmembrane transporter activity
EGX74_RS15385	COG3833	ABC-type maltose transport systems, permease component
EGX74_RS15390	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX74_RS15410	COG0584	glycerophosphoryl diester phosphodiesterase
EGX74_RS15415	COG1940	carbohydrate kinase activity
EGX74_RS15430	COG3381	protein complex oligomerization
EGX74_RS15445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX74_RS15455	COG0728	peptidoglycan biosynthetic process
EGX74_RS15475	COG3102	Protein conserved in bacteria
EGX74_RS15495	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EGX74_RS15500	COG1801	Protein of unknown function DUF72
EGX74_RS15510	COG0494	nUDIX hydrolase
EGX74_RS15540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX74_RS15550	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EGX74_RS15555	COG0739	heme binding
EGX74_RS15560	COG1560	Kdo2-lipid A biosynthetic process
EGX74_RS15570	COG0469	pyruvate kinase activity
EGX74_RS15575	COG1737	Transcriptional regulator
EGX74_RS15580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX74_RS15590	COG0800	Aldolase
EGX74_RS15605	COG0251	oxidation-reduction process
EGX74_RS15610	COG1199	ATP-dependent helicase activity
EGX74_RS15620	COG3065	identical protein binding
EGX74_RS15630	COG0318	PFAM AMP-dependent synthetase and ligase
EGX74_RS15635	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EGX74_RS15640	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EGX74_RS15645	COG2894	cell division
EGX74_RS15660	COG2951	lytic endotransglycosylase activity
EGX74_RS15665	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX74_RS15675	COG0582	viral genome integration into host DNA
EGX74_RS15770	COG3328	transposase activity
EGX74_RS15935	COG3328	transposase activity
EGX74_RS15945	COG1104	cysteine desulfurase activity
EGX74_RS15980	COG2719	SpoVR family
EGX74_RS15990	COG2814	Major facilitator Superfamily
EGX74_RS16000	COG0583	DNA-binding transcription factor activity
EGX74_RS16015	COG2766	serine protein kinase
EGX74_RS16025	COG3713	MltA-interacting MipA family protein
EGX74_RS16045	COG3139	Protein of unknown function (DUF1315)
EGX74_RS16050	COG1335	isochorismatase
EGX74_RS16055	COG0252	asparaginase activity
EGX74_RS16060	COG0616	signal peptide processing
EGX74_RS16065	COG0778	Nitroreductase
EGX74_RS16070	COG0709	Synthesizes selenophosphate from selenide and ATP
EGX74_RS16075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX74_RS16085	COG0494	nUDIX hydrolase
EGX74_RS16090	COG0708	Exodeoxyribonuclease III
EGX74_RS16095	COG0583	DNA-binding transcription factor activity
EGX74_RS16115	COG3328	transposase activity
EGX74_RS16120	COG0788	formyltetrahydrofolate deformylase activity
EGX74_RS16130	COG0745	RESPONSE REGULATOR receiver
EGX74_RS16165	COG1454	alcohol dehydrogenase
EGX74_RS16165	COG1012	belongs to the aldehyde dehydrogenase family
EGX74_RS16175	COG2095	MarC family integral membrane protein
EGX74_RS16185	COG0601	transmembrane transport
EGX74_RS16190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX74_RS16195	COG0444	Belongs to the ABC transporter superfamily
EGX74_RS16200	COG4608	Belongs to the ABC transporter superfamily
EGX74_RS16240	COG2350	Protein conserved in bacteria
EGX74_RS16245	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EGX74_RS16250	COG3328	transposase activity
EGX74_RS16290	COG3047	cAMP biosynthetic process
EGX74_RS16310	COG0135	phosphoribosylanthranilate isomerase activity
EGX74_RS16310	COG0134	indole-3-glycerol-phosphate synthase activity
EGX74_RS16320	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX74_RS16345	COG0009	L-threonylcarbamoyladenylate synthase
EGX74_RS16350	COG1187	pseudouridine synthase activity
EGX74_RS16360	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS16365	COG0616	signal peptide processing
EGX74_RS16385	COG0583	DNA-binding transcription factor activity
EGX74_RS16395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGX74_RS16405	COG0671	phosphoesterase, PA-phosphatase related
EGX74_RS16410	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EGX74_RS16415	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EGX74_RS16430	COG0023	Translation Initiation Factor
EGX74_RS16450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX74_RS16455	COG2879	small protein
EGX74_RS16460	COG1966	Carbon starvation protein
EGX74_RS16470	COG2271	Major facilitator Superfamily
EGX74_RS16475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX74_RS16480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX74_RS16490	COG4659	FMN binding
EGX74_RS16495	COG4658	electron transport chain
EGX74_RS16500	COG2207	Transcriptional regulator
EGX74_RS16500	COG3708	Transcriptional regulator
EGX74_RS16535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX74_RS16540	COG2274	protein secretion by the type I secretion system
EGX74_RS16555	COG1879	ABC-type sugar transport system periplasmic component
EGX74_RS16560	COG1129	ABC transporter
EGX74_RS16565	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS16575	COG0673	inositol 2-dehydrogenase activity
EGX74_RS16580	COG0385	Bile acid
EGX74_RS16590	COG5339	Protein conserved in bacteria
EGX74_RS16600	COG0114	fumarate hydratase activity
EGX74_RS16610	COG2814	Major facilitator Superfamily
EGX74_RS16615	COG0583	DNA-binding transcription factor activity
EGX74_RS16620	COG1940	carbohydrate kinase activity
EGX74_RS16625	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGX74_RS16630	COG0038	chloride channel
EGX74_RS16640	COG1609	Transcriptional regulator
EGX74_RS16660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX74_RS16670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX74_RS16700	COG0028	Belongs to the TPP enzyme family
EGX74_RS16705	COG0440	acetolactate synthase activity
EGX74_RS16710	COG1011	Hydrolase
EGX74_RS16725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX74_RS16730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGX74_RS16735	COG0589	response to stress
EGX74_RS16740	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EGX74_RS16745	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EGX74_RS16760	COG0531	amino acid
EGX74_RS16770	COG0745	RESPONSE REGULATOR receiver
EGX74_RS16775	COG2205	protein histidine kinase activity
EGX74_RS16780	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EGX74_RS16820	COG3591	Belongs to the peptidase S1B family
EGX74_RS16835	COG1643	Atp-dependent helicase
EGX74_RS16845	COG2390	Transcriptional regulator
EGX74_RS16850	COG0246	Mannitol dehydrogenase
EGX74_RS16855	COG3784	Protein of unknown function (DUF1318)
EGX74_RS16865	COG2911	Protein conserved in bacteria
EGX74_RS16870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX74_RS16875	COG3187	Heat shock protein
EGX74_RS16880	COG3042	response to heat
EGX74_RS16885	COG1285	pathogenesis
EGX74_RS16895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX74_RS16895	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGX74_RS16895	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGX74_RS16895	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGX74_RS16905	COG0657	acetylesterase activity
EGX74_RS16925	COG4166	transmembrane transport
EGX74_RS16930	COG2866	Carboxypeptidase
EGX74_RS16935	COG4948	Mandelate Racemase Muconate Lactonizing
EGX74_RS16940	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGX74_RS16955	COG5642	Protein of unknown function (DUF2384)
EGX74_RS16960	COG5654	RES domain protein
EGX74_RS16970	COG3106	COG3106 Predicted ATPase
EGX74_RS16980	COG1983	PspC domain protein
EGX74_RS16990	COG1842	Phage shock protein A
EGX74_RS16995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EGX74_RS17015	COG4166	transmembrane transport
EGX74_RS17020	COG4168	peptide transport system, permease
EGX74_RS17025	COG4171	peptide transport system, permease
EGX74_RS17035	COG4172	Belongs to the ABC transporter superfamily
EGX74_RS17040	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX74_RS17040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX74_RS17045	COG3104	oligopeptide transport
EGX74_RS17060	COG0625	glutathione transferase activity
EGX74_RS17080	COG3895	Periplasmic Protein
EGX74_RS17090	COG3133	Outer membrane lipoprotein
EGX74_RS17105	COG2194	sulfuric ester hydrolase activity
EGX74_RS17110	COG1309	transcriptional regulator
EGX74_RS17115	COG1902	pentaerythritol trinitrate reductase activity
EGX74_RS17125	COG0346	lactoylglutathione lyase activity
EGX74_RS17130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX74_RS17140	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGX74_RS17150	COG0791	NLP P60 protein
EGX74_RS17170	COG0583	DNA-binding transcription factor activity
EGX74_RS17175	COG2814	Major facilitator Superfamily
EGX74_RS17180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGX74_RS17185	COG0307	riboflavin synthase, alpha
EGX74_RS17235	COG1388	LysM domain
EGX74_RS17235	COG1376	ErfK ybiS ycfS ynhG family protein
EGX74_RS17250	COG0719	Fe-S assembly protein
EGX74_RS17255	COG0396	ATPase activity
EGX74_RS17260	COG0719	Fe-S assembly protein
EGX74_RS17265	COG0316	Belongs to the HesB IscA family
EGX74_RS17275	COG2050	protein possibly involved in aromatic compounds catabolism
EGX74_RS17280	COG0277	FAD linked oxidase domain protein
EGX74_RS17280	COG0247	lactate metabolic process
EGX74_RS17285	COG0628	permease
EGX74_RS17295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX74_RS17295	COG0574	Belongs to the PEP-utilizing enzyme family
EGX74_RS17320	COG0791	NLP P60 protein
EGX74_RS17370	COG0386	Belongs to the glutathione peroxidase family
EGX74_RS17385	COG0776	regulation of translation
EGX74_RS17390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX74_RS17390	COG0072	phenylalanine-tRNA ligase activity
EGX74_RS17425	COG4249	Peptidase C14 caspase catalytic subunit p20
EGX74_RS17450	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX74_RS17455	COG1121	(ABC) transporter
EGX74_RS17460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX74_RS17465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX74_RS17475	COG3001	Fructosamine kinase
EGX74_RS17485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX74_RS17490	COG3328	transposase activity
EGX74_RS17495	COG1917	Cupin 2, conserved barrel domain protein
EGX74_RS17505	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS17515	COG1175	transmembrane transport
EGX74_RS17520	COG0395	ABC-type sugar transport system, permease component
EGX74_RS17525	COG3842	ATPase activity
EGX74_RS17530	COG1653	transport
EGX74_RS17535	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGX74_RS17540	COG1988	membrane-bound metal-dependent
EGX74_RS17545	COG1823	symporter activity
EGX74_RS17550	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX74_RS17560	COG0823	Involved in the tonB-independent uptake of proteins
EGX74_RS17565	COG2814	Major facilitator Superfamily
EGX74_RS17570	COG3121	Chaperone
EGX74_RS17585	COG3121	Chaperone
EGX74_RS17590	COG3539	Fimbrial protein
EGX74_RS17605	COG0793	Belongs to the peptidase S41A family
EGX74_RS17615	COG1956	GAF domain-containing protein
EGX74_RS17620	COG2995	paraquat-inducible protein a
EGX74_RS17625	COG3008	intermembrane lipid transfer
EGX74_RS17645	COG3121	Chaperone
EGX74_RS17705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX74_RS17715	COG5295	Hep Hag repeat protein
EGX74_RS17725	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX74_RS17735	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EGX74_RS17740	COG0745	RESPONSE REGULATOR receiver
EGX74_RS17750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGX74_RS17755	COG0840	transmembrane signaling receptor activity
EGX74_RS17760	COG0840	transmembrane signaling receptor activity
EGX74_RS17780	COG2964	Protein conserved in bacteria
EGX74_RS17790	COG0251	oxidation-reduction process
EGX74_RS17795	COG2271	Major facilitator Superfamily
EGX74_RS17800	COG0835	chemotaxis
EGX74_RS17805	COG2198	Histidine kinase
EGX74_RS17805	COG0643	Histidine kinase
EGX74_RS17810	COG1360	Flagellar Motor Protein
EGX74_RS17835	COG1285	pathogenesis
EGX74_RS17860	COG3321	synthase
EGX74_RS17860	COG0604	alcohol dehydrogenase
EGX74_RS17860	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS17870	COG1522	sequence-specific DNA binding
EGX74_RS17890	COG1733	regulation of RNA biosynthetic process
EGX74_RS17895	COG0702	epimerase
EGX74_RS17900	COG0840	transmembrane signaling receptor activity
EGX74_RS17915	COG0538	isocitrate dehydrogenase activity
EGX74_RS17920	COG1187	pseudouridine synthase activity
EGX74_RS17940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGX74_RS17950	COG0745	RESPONSE REGULATOR receiver
EGX74_RS17960	COG2850	peptidyl-arginine hydroxylation
EGX74_RS17985	COG1940	carbohydrate kinase activity
EGX74_RS17990	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX74_RS18000	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX74_RS18005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX74_RS18010	COG3134	Outer membrane lipoprotein
EGX74_RS18020	COG3328	transposase activity
EGX74_RS18040	COG1252	NADH dehydrogenase
EGX74_RS18050	COG1472	Belongs to the glycosyl hydrolase 3 family
EGX74_RS18065	COG5633	Lipoprotein
EGX74_RS18070	COG0537	adenosine 5'-monophosphoramidase activity
EGX74_RS18075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGX74_RS18090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX74_RS18090	COG1263	PTS System
EGX74_RS18095	COG0084	hydrolase, TatD family'
EGX74_RS18100	COG0470	DNA polymerase III
EGX74_RS18110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGX74_RS18115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX74_RS18125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX74_RS18155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGX74_RS18160	COG1399	metal-binding, possibly nucleic acid-binding protein
EGX74_RS18165	COG0424	maF-like protein
EGX74_RS18170	COG0564	pseudouridine synthase activity
EGX74_RS18180	COG1530	ribonuclease E activity
EGX74_RS18185	COG3328	transposase activity
EGX74_RS18200	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EGX74_RS18225	COG3328	transposase activity
EGX74_RS18245	COG0628	permease
EGX74_RS18265	COG3916	Acyl-homoserine-lactone synthase
EGX74_RS18270	COG2771	luxR family
EGX74_RS18275	COG0583	DNA-binding transcription factor activity
EGX74_RS18285	COG0477	Major facilitator Superfamily
EGX74_RS18295	COG0667	Aldo Keto reductase
EGX74_RS18320	COG1203	CRISPR-associated helicase, Cas3
EGX74_RS18325	COG1518	maintenance of DNA repeat elements
EGX74_RS18330	COG0668	transmembrane transport
EGX74_RS18350	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EGX74_RS18355	COG0395	ABC-type sugar transport system, permease component
EGX74_RS18370	COG1609	Transcriptional regulator
EGX74_RS18380	COG3842	ATPase activity
EGX74_RS18390	COG3210	domain, Protein
EGX74_RS18395	COG3210	domain, Protein
EGX74_RS18415	COG3210	domain, Protein
EGX74_RS18435	COG3210	domain, Protein
EGX74_RS18440	COG2831	hemolysin activation secretion protein
EGX74_RS18445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX74_RS18455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX74_RS18465	COG0473	3-isopropylmalate dehydrogenase activity
EGX74_RS18470	COG0583	DNA-binding transcription factor activity
EGX74_RS18475	COG1609	Transcriptional regulator
EGX74_RS18480	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS18485	COG1129	ABC transporter
EGX74_RS18490	COG1879	ABC-type sugar transport system periplasmic component
EGX74_RS18495	COG1063	alcohol dehydrogenase
EGX74_RS18515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGX74_RS18545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX74_RS18550	COG0765	amino acid transport
EGX74_RS18555	COG1126	abc transporter atp-binding protein
EGX74_RS18590	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX74_RS18595	COG1177	transmembrane transport
EGX74_RS18600	COG0443	Heat shock 70 kDa protein
EGX74_RS18605	COG2239	Acts as a magnesium transporter
EGX74_RS18620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGX74_RS18630	COG0581	inorganic phosphate transmembrane transporter activity
EGX74_RS18645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX74_RS18650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGX74_RS18675	COG1393	Belongs to the ArsC family
EGX74_RS18680	COG4783	chaperone-mediated protein folding
EGX74_RS18685	COG0628	permease
EGX74_RS18700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGX74_RS18705	COG2716	regulation of RNA biosynthetic process
EGX74_RS18715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EGX74_RS18735	COG2321	neutral zinc metallopeptidase
EGX74_RS18760	COG1876	peptidase activity
EGX74_RS18770	COG1393	Belongs to the ArsC family
EGX74_RS18785	COG1175	transmembrane transport
EGX74_RS18790	COG3842	ATPase activity
EGX74_RS18800	COG3119	arylsulfatase activity
EGX74_RS18805	COG0641	radical SAM
EGX74_RS18810	COG1988	membrane-bound metal-dependent
EGX74_RS18820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX74_RS18830	COG2197	response regulator
EGX74_RS18835	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX74_RS18835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX74_RS18840	COG3062	negative regulation of establishment of protein localization
EGX74_RS18850	COG3043	anaerobic respiration
EGX74_RS18855	COG3005	denitrification pathway
EGX74_RS18900	COG3111	PFAM Bacterial OB fold (BOF) protein
EGX74_RS18910	COG2837	iron assimilation
EGX74_RS18915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX74_RS18925	COG4886	Leucine-rich repeat (LRR) protein
EGX74_RS18935	COG2731	YhcH YjgK YiaL family protein
EGX74_RS18945	COG1737	Transcriptional regulator
EGX74_RS18955	COG4150	thiosulfate binding
EGX74_RS18960	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGX74_RS18965	COG4208	sulfate ABC transporter
EGX74_RS18970	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGX74_RS18985	COG0745	RESPONSE REGULATOR receiver
EGX74_RS18990	COG3850	Histidine kinase
EGX74_RS18990	COG5002	protein histidine kinase activity
EGX74_RS19000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGX74_RS19020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX74_RS19035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX74_RS19040	COG0745	RESPONSE REGULATOR receiver
EGX74_RS19045	COG2205	protein histidine kinase activity
EGX74_RS19085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX74_RS19095	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EGX74_RS19110	COG3530	Putative quorum-sensing-regulated virulence factor
EGX74_RS19185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX74_RS19200	COG0667	Aldo Keto reductase
EGX74_RS19225	COG0436	Aminotransferase
EGX74_RS19235	COG3038	cytochrome b561
EGX74_RS19265	COG3381	protein complex oligomerization
EGX74_RS19280	COG3302	dmso reductase anchor subunit
EGX74_RS19285	COG0437	4 iron, 4 sulfur cluster binding
EGX74_RS19290	COG0243	molybdopterin cofactor binding
EGX74_RS19325	COG2951	lytic endotransglycosylase activity
EGX74_RS19385	COG3121	Chaperone
EGX74_RS19390	COG3188	usher protein
EGX74_RS19400	COG3328	transposase activity
EGX74_RS19405	COG3188	usher protein
EGX74_RS19495	COG2824	Alkylphosphonate utilization operon protein PhnA
EGX74_RS19505	COG1704	LemA family
EGX74_RS19525	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX74_RS19530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX74_RS19535	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX74_RS19545	COG1138	Cytochrome C-type biogenesis protein
EGX74_RS19550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX74_RS19555	COG4235	cytochrome complex assembly
EGX74_RS19555	COG3088	subunit of a heme lyase
EGX74_RS19560	COG3088	subunit of a heme lyase
EGX74_RS19560	COG4235	cytochrome complex assembly
EGX74_RS19575	COG3691	Protein conserved in bacteria
EGX74_RS19590	COG2062	phosphohistidine phosphatase, SixA
EGX74_RS19600	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX74_RS19615	COG0730	response to heat
EGX74_RS19620	COG3101	peptidyl-lysine hydroxylation
EGX74_RS19635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX74_RS19640	COG1794	racemase activity, acting on amino acids and derivatives
EGX74_RS19655	COG0697	spore germination
EGX74_RS19670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX74_RS19680	COG0586	Pfam SNARE associated Golgi protein
EGX74_RS19690	COG0285	dihydrofolate synthase activity
EGX74_RS19695	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EGX74_RS19700	COG1286	toxin biosynthetic process
EGX74_RS19705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGX74_RS19715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX74_RS19720	COG4215	(ABC) transporter
EGX74_RS19725	COG4160	amino acid transport
EGX74_RS19730	COG4598	ABC transporter
EGX74_RS19735	COG1090	epimerase
EGX74_RS19750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EGX74_RS19755	COG3037	sugar-specific permease SgaT UlaA
EGX74_RS19760	COG3328	transposase activity
EGX74_RS19780	COG1609	Transcriptional regulator
EGX74_RS19785	COG0280	phosphate acetyltransferase
EGX74_RS19785	COG0857	belongs to the CobB CobQ family
EGX74_RS19805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX74_RS19810	COG0490	domain, Protein
EGX74_RS19810	COG0471	metal ion transport
EGX74_RS19825	COG0436	Aminotransferase
EGX74_RS19830	COG0583	DNA-binding transcription factor activity
EGX74_RS19840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX74_RS19860	COG1034	ATP synthesis coupled electron transport
EGX74_RS19875	COG0839	Belongs to the complex I subunit 6 family
EGX74_RS19885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX74_RS19890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX74_RS19905	COG2731	YhcH YjgK YiaL family protein
EGX74_RS19910	COG3265	gluconokinase activity
EGX74_RS19915	COG1028	Short-chain dehydrogenase reductase Sdr
EGX74_RS19920	COG1649	PFAM Uncharacterised BCR, COG1649
EGX74_RS19925	COG1609	Transcriptional regulator
EGX74_RS19930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX74_RS19945	COG0129	dihydroxy-acid dehydratase activity
EGX74_RS19960	COG4575	ribosome binding
EGX74_RS19970	COG1169	isochorismate synthase
EGX74_RS19985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EGX74_RS20000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX74_RS20050	COG3842	ATPase activity
EGX74_RS20080	COG0745	RESPONSE REGULATOR receiver
EGX74_RS20085	COG3422	double-strand break repair
EGX74_RS20090	COG0826	peptidase U32
EGX74_RS20115	COG0351	phosphomethylpyrimidine kinase
EGX74_RS20130	COG3328	transposase activity
EGX74_RS20180	COG0516	GMP reductase activity
EGX74_RS20180	COG0517	IMP dehydrogenase activity
EGX74_RS20195	COG1645	bacterial-type flagellum-dependent swarming motility
EGX74_RS20210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX74_RS20215	COG2976	Protein conserved in bacteria
EGX74_RS20260	COG3468	outer membrane autotransporter barrel domain protein
EGX74_RS20265	COG3468	outer membrane autotransporter barrel domain protein
EGX74_RS20290	COG2975	iron-sulfur cluster assembly
EGX74_RS20295	COG0633	Ferredoxin
EGX74_RS20300	COG0443	Heat shock 70 kDa protein
EGX74_RS20320	COG0822	iron-sulfur transferase activity
EGX74_RS20325	COG1104	cysteine desulfurase activity
EGX74_RS20345	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EGX74_RS20350	COG3683	transport system, periplasmic component
EGX74_RS20355	COG3711	transcriptional antiterminator
EGX74_RS20360	COG2814	Major facilitator Superfamily
EGX74_RS20380	COG1017	nitric oxide dioxygenase activity
EGX74_RS20380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX74_RS20390	COG0347	Belongs to the P(II) protein family
EGX74_RS20395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX74_RS20395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX74_RS20400	COG2204	response regulator
EGX74_RS20405	COG3170	Tfp pilus assembly protein FimV
EGX74_RS20410	COG2205	protein histidine kinase activity
EGX74_RS20460	COG0560	Phosphoserine phosphatase
EGX74_RS20470	COG1737	Transcriptional regulator
EGX74_RS20475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX74_RS20490	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGX74_RS20525	COG3086	response to oxidative stress
EGX74_RS20530	COG3026	antisigma factor binding
EGX74_RS20545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGX74_RS20555	COG0513	Belongs to the DEAD box helicase family
EGX74_RS20605	COG1984	allophanate hydrolase subunit 2
EGX74_RS20615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGX74_RS20620	COG5212	phosphodiesterase
EGX74_RS20630	COG3272	Protein of unknown function (DUF1722)
EGX74_RS20670	COG2205	protein histidine kinase activity
EGX74_RS20675	COG0745	RESPONSE REGULATOR receiver
EGX74_RS20690	COG0033	Phosphoglucomutase
EGX74_RS20695	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EGX74_RS20715	COG2169	Transcriptional regulator
EGX74_RS20715	COG1917	Cupin 2, conserved barrel domain protein
EGX74_RS20720	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGX74_RS20725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX74_RS20730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX74_RS20740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX74_RS20750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX74_RS20765	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EGX74_RS20770	COG4413	Urea transporter
EGX74_RS20780	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EGX74_RS20805	COG0831	urea catabolic process
EGX74_RS20810	COG1124	(ABC) transporter
EGX74_RS20815	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EGX74_RS20820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX74_RS20830	COG0747	negative chemotaxis
EGX74_RS20835	COG1278	Cold shock
EGX74_RS20875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX74_RS20880	COG4175	Glycine betaine
EGX74_RS20885	COG4176	ABC-type proline glycine betaine transport system permease component
EGX74_RS20890	COG2113	Glycine betaine
EGX74_RS20920	COG0582	viral genome integration into host DNA
EGX74_RS20930	COG0596	Alpha beta hydrolase
EGX74_RS20950	COG0735	belongs to the Fur family
EGX74_RS20985	COG2190	(PTS) system
EGX74_RS20985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX74_RS20985	COG1263	PTS System
EGX74_RS20995	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGX74_RS21000	COG1940	carbohydrate kinase activity
EGX74_RS21000	COG1846	Transcriptional regulator
EGX74_RS21005	COG0647	UMP catabolic process
EGX74_RS21010	COG0367	asparagine synthase
EGX74_RS21050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX74_RS21055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGX74_RS21060	COG1702	phosphate starvation-inducible protein PhoH
EGX74_RS21070	COG4535	Mg2 and Co2 transporter CorC
EGX74_RS21075	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGX74_RS21085	COG0765	amino acid transport
EGX74_RS21090	COG0765	amino acid transport
EGX74_RS21095	COG1126	abc transporter atp-binding protein
EGX74_RS21100	COG2888	peptidyl-tyrosine sulfation
EGX74_RS21115	COG1466	dna polymerase III delta subunit
EGX74_RS21125	COG0799	negative regulation of ribosome biogenesis
EGX74_RS21135	COG0768	penicillin binding
EGX74_RS21140	COG0772	Belongs to the SEDS family
EGX74_RS21145	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX74_RS21150	COG1686	Belongs to the peptidase S11 family
EGX74_RS21175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX74_RS21180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX74_RS21190	COG1278	Cold shock
EGX74_RS21195	COG2197	response regulator
EGX74_RS21220	COG5265	(ABC) transporter
EGX74_RS21230	COG3718	enzyme involved in inositol metabolism
EGX74_RS21240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX74_RS21245	COG0673	inositol 2-dehydrogenase activity
EGX74_RS21250	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX74_RS21255	COG1129	ABC transporter
EGX74_RS21270	COG3962	Belongs to the TPP enzyme family
EGX74_RS21290	COG2373	Large extracellular alpha-helical protein
EGX74_RS21305	COG4953	penicillin-binding protein 1C
EGX74_RS21310	COG3423	Transcriptional regulator
EGX74_RS21365	COG3328	transposase activity
EGX74_RS21380	COG1472	Belongs to the glycosyl hydrolase 3 family
EGX74_RS21390	COG0656	L-ascorbic acid biosynthetic process
EGX74_RS21395	COG0667	Aldo Keto reductase
EGX74_RS21435	COG0671	phosphoesterase, PA-phosphatase related
EGX74_RS21435	COG2453	phosphatase
EGX74_RS21440	COG2267	carboxylic ester hydrolase activity
EGX74_RS21450	COG4589	Belongs to the CDS family
EGX74_RS21455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGX74_RS21470	COG0582	viral genome integration into host DNA
EGX74_RS21505	COG2501	S4 domain
EGX74_RS21525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX74_RS21540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGX74_RS21545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGX74_RS21550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGX74_RS21555	COG4181	ATPase activity
EGX74_RS21560	COG2755	lipolytic protein G-D-S-L family
EGX74_RS21565	COG0300	oxidoreductase activity
EGX74_RS21570	COG3118	belongs to the thioredoxin family
EGX74_RS21575	COG0330	HflC and HflK could
EGX74_RS21580	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGX74_RS21585	COG0789	Transcriptional regulator
EGX74_RS21590	COG2217	Heavy metal translocating P-type atpase
EGX74_RS21595	COG3735	TraB family
EGX74_RS21600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGX74_RS21615	COG2223	nitrite transmembrane transporter activity
EGX74_RS21620	COG4651	solute:proton antiporter activity
EGX74_RS21620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX74_RS21625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX74_RS21630	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGX74_RS21650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX74_RS21700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX74_RS21725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX74_RS21725	COG0543	2 iron, 2 sulfur cluster binding
EGX74_RS21755	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX74_RS21765	COG2832	Protein of unknown function (DUF454)
EGX74_RS21780	COG3264	Mechanosensitive ion channel
EGX74_RS21780	COG1196	nuclear chromosome segregation
EGX74_RS21785	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EGX74_RS21790	COG1309	transcriptional regulator
EGX74_RS21795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX74_RS21800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX74_RS21810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX74_RS21835	COG3695	enzyme binding
EGX74_RS21840	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EGX74_RS21845	COG1946	Acyl-CoA thioesterase
EGX74_RS21850	COG0004	ammonium transporteR
EGX74_RS21855	COG0347	Belongs to the P(II) protein family
EGX74_RS21860	COG1132	(ABC) transporter
EGX74_RS21865	COG1132	(ABC) transporter
EGX74_RS21870	COG1522	sequence-specific DNA binding
EGX74_RS21910	COG0824	Thioesterase
EGX74_RS21915	COG1555	photosystem II stabilization
EGX74_RS21920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX74_RS21925	COG0776	regulation of translation
EGX74_RS21930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGX74_RS21955	COG0271	Belongs to the BolA IbaG family
EGX74_RS21960	COG3056	Lipoprotein
EGX74_RS21965	COG2223	nitrite transmembrane transporter activity
EGX74_RS21975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX74_RS21980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX74_RS21985	COG1845	cytochrome c oxidase, subunit III
EGX74_RS21990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX74_RS22000	COG2814	Major facilitator Superfamily
EGX74_RS22015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGX74_RS22020	COG0693	protein deglycase activity
EGX74_RS22035	COG0142	geranyltranstransferase activity
EGX74_RS22050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGX74_RS22055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGX74_RS22070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX74_RS22070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX74_RS22100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX74_RS22105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX74_RS22110	COG1862	Preprotein translocase
EGX74_RS22130	COG0450	alkyl hydroperoxide reductase
EGX74_RS22155	COG0366	Alpha amylase catalytic
EGX74_RS22175	COG5002	protein histidine kinase activity
EGX74_RS22180	COG0745	RESPONSE REGULATOR receiver
EGX74_RS22185	COG0420	3'-5' exonuclease activity
EGX74_RS22190	COG0419	ATPase involved in DNA repair
EGX74_RS22195	COG1940	carbohydrate kinase activity
EGX74_RS22225	COG2226	methyltransferase
EGX74_RS22285	COG0583	DNA-binding transcription factor activity
EGX74_RS22290	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX74_RS22310	COG1477	protein flavinylation
EGX74_RS22330	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX74_RS22360	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EGX74_RS22525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX74_RS22530	COG1475	DNA binding
EGX74_RS22685	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGX74_RS22695	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGX74_RS22775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX74_RS22875	COG1475	DNA binding
EGX74_RS23000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX74_RS23010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGX74_RS23055	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGX74_RS23095	COG3328	transposase activity
EGX74_RS23120	COG3344	reverse transcriptase
EGX74_RS23135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX74_RS23235	COG1475	DNA binding
EGX74_RS23360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX74_RS23370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGX74_RS23530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX74_RS23535	COG1475	DNA binding
EGX74_RS23670	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGX74_RS23670	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGX74_RS23680	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1