locus-tag	class	description
Y_RS00005	COG0716	FMN binding
Y_RS00010	COG1522	sequence-specific DNA binding
Y_RS00040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y_RS00050	COG0477	Major facilitator Superfamily
Y_RS00055	COG2186	Transcriptional regulator
Y_RS00105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Y_RS00110	COG2224	Isocitrate lyase
Y_RS00120	COG1414	Transcriptional regulator
Y_RS00125	COG1414	Transcriptional regulator
Y_RS00150	COG0527	aspartate kinase activity
Y_RS00165	COG3833	ABC-type maltose transport systems, permease component
Y_RS00170	COG1175	transmembrane transport
Y_RS00255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Y_RS00260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Y_RS00265	COG1494	fructose-1,6-bisphosphatase
Y_RS00275	COG3152	Membrane
Y_RS00290	COG0583	DNA-binding transcription factor activity
Y_RS00295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Y_RS00300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Y_RS00305	COG0471	metal ion transport
Y_RS00315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Y_RS00335	COG3678	ATP-independent chaperone mediated protein folding
Y_RS00340	COG0745	RESPONSE REGULATOR receiver
Y_RS00345	COG2205	protein histidine kinase activity
Y_RS00350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Y_RS00350	COG2169	Transcriptional regulator
Y_RS00355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Y_RS00360	COG1045	serine acetyltransferase
Y_RS00380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Y_RS00385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Y_RS00395	COG4942	peptidase
Y_RS00410	COG0156	8-amino-7-oxononanoate synthase activity
Y_RS00420	COG0859	PFAM glycosyl transferase family 9
Y_RS00425	COG0859	PFAM glycosyl transferase family 9
Y_RS00430	COG1519	Transferase
Y_RS00465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Y_RS00490	COG1561	YicC-like family, N-terminal region
Y_RS00495	COG2860	membrane
Y_RS00515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Y_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Y_RS00525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Y_RS00530	COG0786	glutamate:sodium symporter activity
Y_RS00535	COG2233	PERMEase
Y_RS00540	COG2982	Protein involved in outer membrane biogenesis
Y_RS00545	COG0456	acetyltransferase
Y_RS00560	COG0435	Glutathione S-transferase
Y_RS00565	COG0583	DNA-binding transcription factor activity
Y_RS00570	COG1741	Belongs to the pirin family
Y_RS00575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Y_RS00595	COG2823	Periplasmic or secreted lipoprotein
Y_RS00605	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Y_RS00615	COG2198	Histidine kinase
Y_RS00615	COG0784	Response regulator, receiver
Y_RS00615	COG5002	protein histidine kinase activity
Y_RS00625	COG1242	4 iron, 4 sulfur cluster binding
Y_RS00630	COG0067	glutamate synthase
Y_RS00630	COG0069	glutamate synthase activity
Y_RS00630	COG0070	glutamate synthase
Y_RS00635	COG0493	'glutamate synthase
Y_RS00645	COG2969	positive regulation of protein catabolic process
Y_RS00650	COG0625	glutathione transferase activity
Y_RS00670	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Y_RS00675	COG3105	Protein conserved in bacteria
Y_RS00680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Y_RS00690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Y_RS00700	COG5007	Belongs to the BolA IbaG family
Y_RS00705	COG3113	response to antibiotic
Y_RS00710	COG2854	intermembrane phospholipid transfer
Y_RS00715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Y_RS00720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Y_RS00725	COG1127	ABC transporter
Y_RS00730	COG0530	calcium, potassium:sodium antiporter activity
Y_RS00735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Y_RS00735	COG0517	IMP dehydrogenase activity
Y_RS00740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Y_RS00745	COG3117	lipopolysaccharide transmembrane transporter activity
Y_RS00750	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Y_RS00755	COG1137	ATPase activity
Y_RS00760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Y_RS00780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y_RS00805	COG1609	Transcriptional regulator
Y_RS00810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Y_RS00810	COG1263	PTS System
Y_RS00815	COG0366	Alpha amylase catalytic
Y_RS00820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Y_RS00825	COG3783	Cytochrome b(562)
Y_RS00835	COG0312	modulator of DNA gyrase
Y_RS00845	COG2732	(Barnase) inhibitor
Y_RS00860	COG1012	belongs to the aldehyde dehydrogenase family
Y_RS00880	COG0583	DNA-binding transcription factor activity
Y_RS00935	COG0312	modulator of DNA gyrase
Y_RS00940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Y_RS00945	COG3164	Protein of unknown function
Y_RS00950	COG1530	ribonuclease E activity
Y_RS00955	COG0424	maF-like protein
Y_RS00960	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Y_RS00965	COG1792	Involved in formation and maintenance of cell shape
Y_RS00970	COG1077	Cell shape determining protein MreB Mrl
Y_RS00975	COG2199	diguanylate cyclase activity
Y_RS00975	COG2200	EAL domain
Y_RS00980	COG0604	alcohol dehydrogenase
Y_RS00985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Y_RS01000	COG0511	ligase activity, forming carbon-carbon bonds
Y_RS01005	COG0439	Biotin carboxylase
Y_RS01010	COG3924	membrane
Y_RS01015	COG4145	pantothenate transmembrane transporter activity
Y_RS01025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Y_RS01030	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Y_RS01055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Y_RS01065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Y_RS01070	COG3133	Outer membrane lipoprotein
Y_RS01080	COG1278	Cold shock
Y_RS01085	COG1278	Cold shock
Y_RS01110	COG0625	glutathione transferase activity
Y_RS01120	COG1069	ribulokinase activity
Y_RS01130	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS01135	COG1129	ABC transporter
Y_RS01145	COG1560	Kdo2-lipid A biosynthetic process
Y_RS01155	COG0025	NhaP-type Na H and K H
Y_RS01160	COG2252	PERMEase
Y_RS01165	COG3077	Addiction module antitoxin, RelB DinJ family
Y_RS01175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y_RS01185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Y_RS01190	COG0431	NADPH-dependent FMN reductase
Y_RS01195	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Y_RS01200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y_RS01205	COG1869	D-ribose catabolic process
Y_RS01210	COG2207	Transcriptional regulator
Y_RS01210	COG1917	Cupin 2, conserved barrel domain protein
Y_RS01215	COG0673	inositol 2-dehydrogenase activity
Y_RS01230	COG3209	COG3209 Rhs family protein
Y_RS01240	COG3501	Rhs element vgr protein
Y_RS01285	COG3501	Rhs element vgr protein
Y_RS01360	COG2801	Transposase and inactivated derivatives
Y_RS01405	COG1575	Belongs to the MenA family. Type 1 subfamily
Y_RS01420	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Y_RS01425	COG1609	Transcriptional regulator
Y_RS01435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Y_RS01445	COG4682	membrane
Y_RS01465	COG0527	aspartate kinase activity
Y_RS01465	COG0460	homoserine dehydrogenase
Y_RS01475	COG2801	Transposase and inactivated derivatives
Y_RS01495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Y_RS01515	COG1629	transport
Y_RS01540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Y_RS01545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Y_RS01545	COG0678	peroxiredoxin activity
Y_RS01630	COG1879	ABC-type sugar transport system periplasmic component
Y_RS01635	COG1129	ABC transporter
Y_RS01640	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS01645	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS01655	COG3085	chromosome segregation
Y_RS01670	COG3978	acetolactate synthase activity
Y_RS01675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Y_RS01720	COG0583	DNA-binding transcription factor activity
Y_RS01760	COG3121	Chaperone
Y_RS01775	COG3121	Chaperone
Y_RS01790	COG3328	transposase activity
Y_RS01800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Y_RS01830	COG3118	belongs to the thioredoxin family
Y_RS01835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Y_RS01840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Y_RS01845	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
Y_RS01850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Y_RS01855	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Y_RS01860	COG1088	dTDP-glucose 4,6-dehydratase activity
Y_RS01865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Y_RS01870	COG0456	acetyltransferase
Y_RS01875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Y_RS01880	COG2244	polysaccharide biosynthetic process
Y_RS01900	COG1113	amino acid transport
Y_RS01930	COG3071	HemY protein
Y_RS01935	COG2959	enzyme of heme biosynthesis
Y_RS01940	COG1587	Uroporphyrinogen-III synthase
Y_RS01950	COG3072	Adenylate cyclase
Y_RS01970	COG3159	Protein conserved in bacteria
Y_RS01975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Y_RS01980	COG1011	Hydrolase
Y_RS01985	COG0210	DNA helicase
Y_RS01995	COG5441	Belongs to the UPF0261 family
Y_RS02000	COG5564	TIM-barrel signal transduction protein
Y_RS02015	COG2050	protein possibly involved in aromatic compounds catabolism
Y_RS02020	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
Y_RS02025	COG0514	ATP-dependent DNA helicase (RecQ)
Y_RS02030	COG1280	lysine exporter protein (LysE YggA)
Y_RS02035	COG1280	lysine exporter protein (LysE YggA)
Y_RS02040	COG2267	carboxylic ester hydrolase activity
Y_RS02045	COG0561	phosphatase activity
Y_RS02055	COG0584	glycerophosphoryl diester phosphodiesterase
Y_RS02065	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Y_RS02075	COG0247	lactate metabolic process
Y_RS02085	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Y_RS02100	COG3714	YhhN family
Y_RS02115	COG3776	membrane
Y_RS02120	COG0742	ribosomal rna small subunit methyltransferase
Y_RS02130	COG0552	protein localization to endoplasmic reticulum
Y_RS02130	COG0552	protein localization to endoplasmic reticulum
Y_RS02135	COG2884	Cell division ATP-binding protein ftsE
Y_RS02140	COG2177	Part of the ABC transporter FtsEX involved in
Y_RS02165	COG0683	leucine binding
Y_RS02175	COG4177	L-phenylalanine transmembrane transporter activity
Y_RS02185	COG0410	ABC transporter
Y_RS02245	COG0584	glycerophosphoryl diester phosphodiesterase
Y_RS02250	COG0679	Auxin Efflux Carrier
Y_RS02255	COG0697	spore germination
Y_RS02260	COG0583	DNA-binding transcription factor activity
Y_RS02270	COG0412	Dienelactone hydrolase
Y_RS02285	COG1966	Carbon starvation protein
Y_RS02290	COG0586	Pfam SNARE associated Golgi protein
Y_RS02295	COG1322	Protein conserved in bacteria
Y_RS02315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Y_RS02325	COG0805	protein transport
Y_RS02360	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Y_RS02385	COG1739	Uncharacterized protein family UPF0029
Y_RS02395	COG1739	Uncharacterized protein family UPF0029
Y_RS02400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Y_RS02405	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
Y_RS02440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Y_RS02500	COG0250	Participates in transcription elongation, termination and antitermination
Y_RS02565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Y_RS02605	COG1515	deoxyribonuclease V activity
Y_RS02625	COG0151	Belongs to the GarS family
Y_RS02665	COG2801	Transposase and inactivated derivatives
Y_RS02690	COG3162	membrane
Y_RS02700	COG1301	dicarboxylic acid transport
Y_RS02810	COG2391	methyltransferase activity
Y_RS02815	COG0425	Belongs to the sulfur carrier protein TusA family
Y_RS02820	COG0583	DNA-binding transcription factor activity
Y_RS02825	COG0814	amino acid
Y_RS02830	COG0626	cystathionine gamma-synthase activity
Y_RS02840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y_RS02845	COG4558	Periplasmic binding protein
Y_RS02850	COG3720	iron ion transport
Y_RS02855	COG4771	TonB-dependent receptor
Y_RS02860	COG0702	epimerase
Y_RS02865	COG3721	Heme iron utilization protein
Y_RS02890	COG1358	cellular component organization or biogenesis
Y_RS02950	COG3121	Chaperone
Y_RS02995	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Y_RS03005	COG0735	belongs to the Fur family
Y_RS03010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Y_RS03035	COG1448	Aminotransferase
Y_RS03040	COG2315	Protein conserved in bacteria
Y_RS03045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Y_RS03050	COG0629	single-stranded DNA binding
Y_RS03060	COG1454	alcohol dehydrogenase
Y_RS03130	COG1309	transcriptional regulator
Y_RS03135	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Y_RS03135	COG0493	'glutamate synthase
Y_RS03140	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Y_RS03145	COG3383	formate dehydrogenase (NAD+) activity
Y_RS03160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Y_RS03205	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Y_RS03215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Y_RS03220	COG1053	succinate dehydrogenase
Y_RS03235	COG3264	Mechanosensitive ion channel
Y_RS03235	COG1511	domain protein
Y_RS03255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Y_RS03275	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Y_RS03280	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Y_RS03280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Y_RS03285	COG0802	atpase or kinase
Y_RS03290	COG0860	N-Acetylmuramoyl-L-alanine amidase
Y_RS03310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Y_RS03315	COG0330	HflC and HflK could
Y_RS03320	COG0330	HflC and HflK could
Y_RS03325	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
Y_RS03340	COG0557	exoribonuclease II activity
Y_RS03345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Y_RS03350	COG1960	acyl-CoA dehydrogenase activity
Y_RS03355	COG3650	response to hydrogen peroxide
Y_RS03375	COG1073	alpha beta
Y_RS03385	COG0360	Binds together with S18 to 16S ribosomal RNA
Y_RS03395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Y_RS03420	COG3061	Opacity-associated protein A
Y_RS03425	COG0545	Peptidyl-prolyl cis-trans isomerase
Y_RS03435	COG0737	Belongs to the 5'-nucleotidase family
Y_RS03445	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
Y_RS03455	COG1253	flavin adenine dinucleotide binding
Y_RS03465	COG0729	surface antigen
Y_RS03470	COG2911	Protein conserved in bacteria
Y_RS03475	COG2105	PFAM AIG2 family protein
Y_RS03480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Y_RS03485	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Y_RS03490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Y_RS03515	COG3423	Transcriptional regulator
Y_RS03525	COG0142	geranyltranstransferase activity
Y_RS03540	COG0697	spore germination
Y_RS03550	COG0642	Histidine kinase
Y_RS03555	COG0745	RESPONSE REGULATOR receiver
Y_RS03560	COG2027	D-alanyl-D-alanine carboxypeptidase
Y_RS03570	COG1534	Rna-binding protein
Y_RS03585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Y_RS03595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Y_RS03615	COG0195	Participates in both transcription termination and antitermination
Y_RS03645	COG2801	Transposase and inactivated derivatives
Y_RS03660	COG0513	Belongs to the DEAD box helicase family
Y_RS03680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Y_RS03690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y_RS03700	COG0826	peptidase U32
Y_RS03705	COG0826	peptidase U32
Y_RS03715	COG3154	lipid carrier protein
Y_RS03720	COG3153	acetyltransferase
Y_RS03740	COG1653	transport
Y_RS03745	COG1175	transmembrane transport
Y_RS03750	COG0395	ABC-type sugar transport system, permease component
Y_RS03755	COG3842	ATPase activity
Y_RS03770	COG0702	epimerase
Y_RS03775	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Y_RS03780	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Y_RS03785	COG3454	Phosphonate metabolism
Y_RS03790	COG4778	phosphonate C-P lyase system protein PhnL
Y_RS03795	COG4107	phosphonate C-P lyase system protein PhnK
Y_RS03800	COG3627	carbon phosphorus lyase activity
Y_RS03805	COG3626	phosphonate metabolism
Y_RS03810	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
Y_RS03815	COG3624	Phosphonate C-P lyase system protein PhnG
Y_RS03820	COG2188	Transcriptional regulator
Y_RS03835	COG4608	Belongs to the ABC transporter superfamily
Y_RS03840	COG0444	Belongs to the ABC transporter superfamily
Y_RS03845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Y_RS03850	COG0601	transmembrane transport
Y_RS03860	COG2731	YhcH YjgK YiaL family protein
Y_RS03870	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
Y_RS03880	COG0525	valine-tRNA ligase activity
Y_RS03885	COG2927	DNA polymerase III (CHI subunit)
Y_RS03895	COG0795	lipopolysaccharide-transporting ATPase activity
Y_RS03900	COG0795	lipopolysaccharide-transporting ATPase activity
Y_RS03910	COG0582	viral genome integration into host DNA
Y_RS03965	COG1459	type II secretion system
Y_RS03970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Y_RS03975	COG4969	Belongs to the N-Me-Phe pilin family
Y_RS03985	COG3023	N-Acetylmuramoyl-L-alanine amidase
Y_RS03990	COG3725	Membrane protein required for beta-lactamase induction
Y_RS03995	COG1113	amino acid transport
Y_RS04000	COG2186	Transcriptional regulator
Y_RS04005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Y_RS04010	COG0508	dehydrogenase complex catalyzes the overall conversion of
Y_RS04015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Y_RS04030	COG1049	propionate catabolic process, 2-methylcitrate cycle
Y_RS04040	COG0697	spore germination
Y_RS04060	COG2132	Multicopper oxidase
Y_RS04065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Y_RS04070	COG0288	reversible hydration of carbon dioxide
Y_RS04075	COG1131	(ABC) transporter
Y_RS04080	COG0842	Transport permease protein
Y_RS04105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Y_RS04110	COG0617	tRNA 3'-terminal CCA addition
Y_RS04115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Y_RS04130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Y_RS04135	COG1643	Atp-dependent helicase
Y_RS04140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Y_RS04145	COG1120	ATPase activity
Y_RS04150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Y_RS04155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y_RS04175	COG2860	membrane
Y_RS04195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Y_RS04200	COG3850	Histidine kinase
Y_RS04200	COG3437	response regulator, receiver
Y_RS04200	COG2205	protein histidine kinase activity
Y_RS04200	COG4999	Histidine kinase
Y_RS04205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Y_RS04215	COG3956	TIGRFAM MazG family protein
Y_RS04235	COG0602	queuosine metabolic process
Y_RS04240	COG0720	synthase
Y_RS04290	COG0529	Catalyzes the synthesis of activated sulfate
Y_RS04330	COG4942	peptidase
Y_RS04330	COG1388	LysM domain
Y_RS04335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Y_RS04350	COG0698	ribose 5-phosphate isomerase
Y_RS04355	COG1063	alcohol dehydrogenase
Y_RS04360	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS04365	COG2376	Dihydroxyacetone kinase
Y_RS04380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Y_RS04400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y_RS04405	COG1858	cytochrome C peroxidase
Y_RS04415	COG4771	TonB-dependent receptor
Y_RS04430	COG0024	Methionine aminopeptidase
Y_RS04440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Y_RS04440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Y_RS04445	COG1070	Carbohydrate kinase
Y_RS04450	COG3623	hexulose-6-phosphate isomerase
Y_RS04455	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS04460	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS04465	COG1129	ABC transporter
Y_RS04480	COG1349	DNA-binding transcription factor activity
Y_RS04485	COG0235	Class ii aldolase
Y_RS04490	COG0243	molybdopterin cofactor binding
Y_RS04495	COG0437	4 iron, 4 sulfur cluster binding
Y_RS04500	COG3302	dmso reductase anchor subunit
Y_RS04505	COG3381	protein complex oligomerization
Y_RS04510	COG3038	cytochrome b561
Y_RS04515	COG3783	Cytochrome b(562)
Y_RS04525	COG1879	ABC-type sugar transport system periplasmic component
Y_RS04535	COG1129	ABC transporter
Y_RS04540	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS04545	COG3959	Transketolase, thiamine diphosphate binding domain
Y_RS04550	COG3958	Transketolase
Y_RS04555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Y_RS04595	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Y_RS04620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Y_RS04625	COG1238	metal cluster binding
Y_RS04630	COG2918	glutathione biosynthetic process
Y_RS04650	COG4536	flavin adenine dinucleotide binding
Y_RS04655	COG4137	Cytochrome C assembly protein
Y_RS04660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Y_RS04695	COG3137	Salt-induced outer membrane protein
Y_RS04700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Y_RS04705	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Y_RS04710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Y_RS04715	COG3279	Response regulator of the LytR AlgR family
Y_RS04720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Y_RS04725	COG0287	Prephenate dehydrogenase
Y_RS04725	COG1605	Chorismate mutase
Y_RS04730	COG1605	Chorismate mutase
Y_RS04730	COG0077	Prephenate dehydratase
Y_RS04745	COG1605	Chorismate mutase
Y_RS04745	COG0077	Prephenate dehydratase
Y_RS04755	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Y_RS04760	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Y_RS04765	COG0564	pseudouridine synthase activity
Y_RS04775	COG0542	response to heat
Y_RS04815	COG5544	Lipoprotein
Y_RS04820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Y_RS04825	COG1042	CoA-binding domain protein
Y_RS04825	COG0045	succinate-CoA ligase (ADP-forming) activity
Y_RS04825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Y_RS04830	COG3148	PFAM DTW domain containing protein
Y_RS04835	COG3118	belongs to the thioredoxin family
Y_RS04840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Y_RS04845	COG2814	Major facilitator Superfamily
Y_RS04850	COG1566	PFAM secretion protein HlyD family protein
Y_RS04855	COG1846	Transcriptional regulator
Y_RS04865	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Y_RS04870	COG2814	Major facilitator Superfamily
Y_RS04910	COG0765	amino acid transport
Y_RS04920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Y_RS04935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Y_RS04960	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
Y_RS04970	COG1960	acyl-CoA dehydrogenase activity
Y_RS04980	COG0121	glutamine amidotransferase
Y_RS04985	COG3034	peptidoglycan biosynthetic process
Y_RS04995	COG1805	sodium ion transport
Y_RS05000	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Y_RS05020	COG1477	protein flavinylation
Y_RS05040	COG2195	Cleaves the N-terminal amino acid of tripeptides
Y_RS05100	COG2226	methyltransferase
Y_RS05135	COG1940	carbohydrate kinase activity
Y_RS05140	COG0419	ATPase involved in DNA repair
Y_RS05145	COG0420	3'-5' exonuclease activity
Y_RS05155	COG0745	RESPONSE REGULATOR receiver
Y_RS05160	COG5002	protein histidine kinase activity
Y_RS05180	COG0366	Alpha amylase catalytic
Y_RS05205	COG0450	alkyl hydroperoxide reductase
Y_RS05225	COG1862	Preprotein translocase
Y_RS05230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Y_RS05235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Y_RS05260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Y_RS05260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Y_RS05275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Y_RS05280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Y_RS05310	COG0142	geranyltranstransferase activity
Y_RS05330	COG0693	protein deglycase activity
Y_RS05335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Y_RS05345	COG2814	Major facilitator Superfamily
Y_RS05355	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Y_RS05360	COG1845	cytochrome c oxidase, subunit III
Y_RS05365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Y_RS05370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Y_RS05380	COG2223	nitrite transmembrane transporter activity
Y_RS05385	COG3056	Lipoprotein
Y_RS05390	COG0271	Belongs to the BolA IbaG family
Y_RS05415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Y_RS05420	COG0776	regulation of translation
Y_RS05425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Y_RS05430	COG1555	photosystem II stabilization
Y_RS05435	COG0824	Thioesterase
Y_RS05445	COG4533	DNA binding
Y_RS05460	COG1522	sequence-specific DNA binding
Y_RS05465	COG1132	(ABC) transporter
Y_RS05470	COG1132	(ABC) transporter
Y_RS05475	COG0347	Belongs to the P(II) protein family
Y_RS05480	COG0004	ammonium transporteR
Y_RS05485	COG1946	Acyl-CoA thioesterase
Y_RS05490	COG3126	Type III secretion system lipoprotein chaperone (YscW)
Y_RS05495	COG3695	enzyme binding
Y_RS05515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Y_RS05525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y_RS05530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y_RS05535	COG1309	transcriptional regulator
Y_RS05540	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Y_RS05545	COG1196	nuclear chromosome segregation
Y_RS05545	COG3264	Mechanosensitive ion channel
Y_RS05570	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Y_RS05600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Y_RS05600	COG0543	2 iron, 2 sulfur cluster binding
Y_RS05625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y_RS05665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y_RS05685	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
Y_RS05690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y_RS05695	COG4651	solute:proton antiporter activity
Y_RS05695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Y_RS05700	COG2223	nitrite transmembrane transporter activity
Y_RS05705	COG0737	Belongs to the 5'-nucleotidase family
Y_RS05710	COG0737	Belongs to the 5'-nucleotidase family
Y_RS05715	COG0737	Belongs to the 5'-nucleotidase family
Y_RS05730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Y_RS05735	COG3735	TraB family
Y_RS05740	COG2217	Heavy metal translocating P-type atpase
Y_RS05745	COG0789	Transcriptional regulator
Y_RS05750	COG1585	Membrane protein implicated in regulation of membrane protease activity
Y_RS05755	COG0330	HflC and HflK could
Y_RS05760	COG3118	belongs to the thioredoxin family
Y_RS05765	COG0300	oxidoreductase activity
Y_RS05770	COG2755	lipolytic protein G-D-S-L family
Y_RS05775	COG4181	ATPase activity
Y_RS05780	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Y_RS05785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Y_RS05790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Y_RS05800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Y_RS05820	COG2501	S4 domain
Y_RS05870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Y_RS05875	COG4589	Belongs to the CDS family
Y_RS05885	COG2267	carboxylic ester hydrolase activity
Y_RS05890	COG2453	phosphatase
Y_RS05890	COG0671	phosphoesterase, PA-phosphatase related
Y_RS05920	COG0667	Aldo Keto reductase
Y_RS05925	COG0656	L-ascorbic acid biosynthetic process
Y_RS05945	COG1472	Belongs to the glycosyl hydrolase 3 family
Y_RS05960	COG3328	transposase activity
Y_RS05965	COG2850	peptidyl-arginine hydroxylation
Y_RS06015	COG3423	Transcriptional regulator
Y_RS06020	COG4953	penicillin-binding protein 1C
Y_RS06035	COG2373	Large extracellular alpha-helical protein
Y_RS06055	COG3962	Belongs to the TPP enzyme family
Y_RS06070	COG1129	ABC transporter
Y_RS06075	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS06080	COG0673	inositol 2-dehydrogenase activity
Y_RS06085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y_RS06095	COG3718	enzyme involved in inositol metabolism
Y_RS06105	COG5265	(ABC) transporter
Y_RS06130	COG2197	response regulator
Y_RS06135	COG1278	Cold shock
Y_RS06145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Y_RS06155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Y_RS06175	COG1686	Belongs to the peptidase S11 family
Y_RS06180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Y_RS06185	COG0772	Belongs to the SEDS family
Y_RS06190	COG0768	penicillin binding
Y_RS06200	COG0799	negative regulation of ribosome biogenesis
Y_RS06210	COG1466	dna polymerase III delta subunit
Y_RS06225	COG2888	peptidyl-tyrosine sulfation
Y_RS06230	COG1126	abc transporter atp-binding protein
Y_RS06235	COG0765	amino acid transport
Y_RS06240	COG0765	amino acid transport
Y_RS06250	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Y_RS06255	COG4535	Mg2 and Co2 transporter CorC
Y_RS06265	COG1702	phosphate starvation-inducible protein PhoH
Y_RS06270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Y_RS06275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Y_RS06315	COG0367	asparagine synthase
Y_RS06320	COG0647	UMP catabolic process
Y_RS06325	COG1940	carbohydrate kinase activity
Y_RS06325	COG1846	Transcriptional regulator
Y_RS06330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Y_RS06340	COG1263	PTS System
Y_RS06340	COG2190	(PTS) system
Y_RS06340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Y_RS06365	COG0735	belongs to the Fur family
Y_RS06385	COG0596	Alpha beta hydrolase
Y_RS06395	COG0582	viral genome integration into host DNA
Y_RS06400	COG2963	transposase activity
Y_RS06405	COG0582	viral genome integration into host DNA
Y_RS06425	COG2113	Glycine betaine
Y_RS06430	COG4176	ABC-type proline glycine betaine transport system permease component
Y_RS06435	COG4175	Glycine betaine
Y_RS06440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Y_RS06480	COG1278	Cold shock
Y_RS06485	COG0747	negative chemotaxis
Y_RS06495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Y_RS06500	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Y_RS06505	COG1124	(ABC) transporter
Y_RS06510	COG0831	urea catabolic process
Y_RS06535	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Y_RS06545	COG4413	Urea transporter
Y_RS06550	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Y_RS06565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Y_RS06575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Y_RS06585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Y_RS06590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Y_RS06595	COG1447	Phosphotransferase system cellobiose-specific component IIA
Y_RS06600	COG1917	Cupin 2, conserved barrel domain protein
Y_RS06600	COG2169	Transcriptional regulator
Y_RS06620	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
Y_RS06625	COG0033	Phosphoglucomutase
Y_RS06645	COG0745	RESPONSE REGULATOR receiver
Y_RS06650	COG2205	protein histidine kinase activity
Y_RS06685	COG3272	Protein of unknown function (DUF1722)
Y_RS06695	COG5212	phosphodiesterase
Y_RS06700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Y_RS06710	COG1984	allophanate hydrolase subunit 2
Y_RS06765	COG0513	Belongs to the DEAD box helicase family
Y_RS06775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Y_RS06790	COG3026	antisigma factor binding
Y_RS06795	COG3086	response to oxidative stress
Y_RS06830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Y_RS06850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Y_RS06855	COG1737	Transcriptional regulator
Y_RS06865	COG0560	Phosphoserine phosphatase
Y_RS06905	COG2205	protein histidine kinase activity
Y_RS06910	COG3170	Tfp pilus assembly protein FimV
Y_RS06915	COG2204	response regulator
Y_RS06920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Y_RS06920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Y_RS06925	COG0347	Belongs to the P(II) protein family
Y_RS06930	COG2188	Transcriptional regulator
Y_RS06935	COG2188	Transcriptional regulator
Y_RS06950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Y_RS06950	COG1017	nitric oxide dioxygenase activity
Y_RS06970	COG2814	Major facilitator Superfamily
Y_RS06975	COG3711	transcriptional antiterminator
Y_RS06980	COG3683	transport system, periplasmic component
Y_RS06985	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Y_RS07005	COG1104	cysteine desulfurase activity
Y_RS07010	COG0822	iron-sulfur transferase activity
Y_RS07030	COG0633	Ferredoxin
Y_RS07035	COG2975	iron-sulfur cluster assembly
Y_RS07055	COG3468	outer membrane autotransporter barrel domain protein
Y_RS07060	COG3468	outer membrane autotransporter barrel domain protein
Y_RS07105	COG2976	Protein conserved in bacteria
Y_RS07110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Y_RS07125	COG1645	bacterial-type flagellum-dependent swarming motility
Y_RS07135	COG0516	GMP reductase activity
Y_RS07135	COG0517	IMP dehydrogenase activity
Y_RS07190	COG3328	transposase activity
Y_RS07205	COG0351	phosphomethylpyrimidine kinase
Y_RS07225	COG0826	peptidase U32
Y_RS07230	COG3422	double-strand break repair
Y_RS07235	COG0745	RESPONSE REGULATOR receiver
Y_RS07240	COG2205	protein histidine kinase activity
Y_RS07245	COG2205	protein histidine kinase activity
Y_RS07270	COG3842	ATPase activity
Y_RS07280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Y_RS07290	COG1176	ABC-type spermidine putrescine transport system, permease component I
Y_RS07295	COG1177	transmembrane transport
Y_RS07300	COG0443	Heat shock 70 kDa protein
Y_RS07305	COG2239	Acts as a magnesium transporter
Y_RS07320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Y_RS07330	COG0581	inorganic phosphate transmembrane transporter activity
Y_RS07350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Y_RS07355	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Y_RS07380	COG1393	Belongs to the ArsC family
Y_RS07385	COG4783	chaperone-mediated protein folding
Y_RS07390	COG0628	permease
Y_RS07410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Y_RS07415	COG2716	regulation of RNA biosynthetic process
Y_RS07425	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Y_RS07445	COG2321	neutral zinc metallopeptidase
Y_RS07465	COG1876	peptidase activity
Y_RS07475	COG1393	Belongs to the ArsC family
Y_RS07490	COG1175	transmembrane transport
Y_RS07495	COG3842	ATPase activity
Y_RS07500	COG3119	arylsulfatase activity
Y_RS07505	COG0641	radical SAM
Y_RS07510	COG1988	membrane-bound metal-dependent
Y_RS07520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y_RS07530	COG2197	response regulator
Y_RS07535	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Y_RS07535	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
Y_RS07540	COG3062	negative regulation of establishment of protein localization
Y_RS07550	COG3043	anaerobic respiration
Y_RS07555	COG3005	denitrification pathway
Y_RS07600	COG3111	PFAM Bacterial OB fold (BOF) protein
Y_RS07610	COG2837	iron assimilation
Y_RS07615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Y_RS07625	COG4886	Leucine-rich repeat (LRR) protein
Y_RS07635	COG2731	YhcH YjgK YiaL family protein
Y_RS07645	COG1737	Transcriptional regulator
Y_RS07655	COG4150	thiosulfate binding
Y_RS07660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Y_RS07665	COG4208	sulfate ABC transporter
Y_RS07670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Y_RS07685	COG0745	RESPONSE REGULATOR receiver
Y_RS07690	COG5002	protein histidine kinase activity
Y_RS07690	COG3850	Histidine kinase
Y_RS07700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Y_RS07720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Y_RS07735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y_RS07740	COG0745	RESPONSE REGULATOR receiver
Y_RS07745	COG2205	protein histidine kinase activity
Y_RS07770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y_RS07780	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Y_RS07795	COG3530	Putative quorum-sensing-regulated virulence factor
Y_RS07850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Y_RS07865	COG0667	Aldo Keto reductase
Y_RS07890	COG0436	Aminotransferase
Y_RS07895	COG3038	cytochrome b561
Y_RS07925	COG3381	protein complex oligomerization
Y_RS07930	COG3302	dmso reductase anchor subunit
Y_RS07935	COG0437	4 iron, 4 sulfur cluster binding
Y_RS07940	COG0243	molybdopterin cofactor binding
Y_RS07975	COG2951	lytic endotransglycosylase activity
Y_RS08035	COG3121	Chaperone
Y_RS08040	COG3188	usher protein
Y_RS08045	COG3328	transposase activity
Y_RS08050	COG3188	usher protein
Y_RS08140	COG2824	Alkylphosphonate utilization operon protein PhnA
Y_RS08150	COG1704	LemA family
Y_RS08170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Y_RS08175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Y_RS08180	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Y_RS08190	COG1138	Cytochrome C-type biogenesis protein
Y_RS08195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Y_RS08200	COG3088	subunit of a heme lyase
Y_RS08200	COG4235	cytochrome complex assembly
Y_RS08205	COG4235	cytochrome complex assembly
Y_RS08205	COG3088	subunit of a heme lyase
Y_RS08220	COG3691	Protein conserved in bacteria
Y_RS08235	COG2062	phosphohistidine phosphatase, SixA
Y_RS08245	COG2890	protein-(glutamine-N5) methyltransferase activity
Y_RS08260	COG0730	response to heat
Y_RS08265	COG3101	peptidyl-lysine hydroxylation
Y_RS08280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Y_RS08285	COG1794	racemase activity, acting on amino acids and derivatives
Y_RS08300	COG0697	spore germination
Y_RS08320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Y_RS08330	COG0586	Pfam SNARE associated Golgi protein
Y_RS08340	COG0285	dihydrofolate synthase activity
Y_RS08345	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
Y_RS08350	COG1286	toxin biosynthetic process
Y_RS08355	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Y_RS08365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y_RS08370	COG4215	(ABC) transporter
Y_RS08375	COG4160	amino acid transport
Y_RS08380	COG4598	ABC transporter
Y_RS08385	COG1090	epimerase
Y_RS08395	COG0622	Phosphoesterase
Y_RS08400	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Y_RS08405	COG3037	sugar-specific permease SgaT UlaA
Y_RS08410	COG3328	transposase activity
Y_RS08425	COG1609	Transcriptional regulator
Y_RS08430	COG0280	phosphate acetyltransferase
Y_RS08430	COG0857	belongs to the CobB CobQ family
Y_RS08455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Y_RS08460	COG0471	metal ion transport
Y_RS08460	COG0490	domain, Protein
Y_RS08475	COG0436	Aminotransferase
Y_RS08485	COG0583	DNA-binding transcription factor activity
Y_RS08495	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Y_RS08515	COG1034	ATP synthesis coupled electron transport
Y_RS08530	COG0839	Belongs to the complex I subunit 6 family
Y_RS08540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Y_RS08545	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Y_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS08570	COG3265	gluconokinase activity
Y_RS08580	COG1649	PFAM Uncharacterised BCR, COG1649
Y_RS08585	COG1609	Transcriptional regulator
Y_RS08595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Y_RS08610	COG0129	dihydroxy-acid dehydratase activity
Y_RS08625	COG4575	ribosome binding
Y_RS08635	COG1169	isochorismate synthase
Y_RS08650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Y_RS08665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Y_RS08700	COG1126	abc transporter atp-binding protein
Y_RS08705	COG0765	amino acid transport
Y_RS08710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y_RS08740	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Y_RS08760	COG1063	alcohol dehydrogenase
Y_RS08765	COG1879	ABC-type sugar transport system periplasmic component
Y_RS08770	COG1129	ABC transporter
Y_RS08775	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS08780	COG1609	Transcriptional regulator
Y_RS08785	COG0583	DNA-binding transcription factor activity
Y_RS08790	COG0473	3-isopropylmalate dehydrogenase activity
Y_RS08800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Y_RS08810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Y_RS08815	COG2831	hemolysin activation secretion protein
Y_RS08820	COG3210	domain, Protein
Y_RS08840	COG3210	domain, Protein
Y_RS08860	COG3210	domain, Protein
Y_RS08870	COG3842	ATPase activity
Y_RS08880	COG1609	Transcriptional regulator
Y_RS08895	COG0395	ABC-type sugar transport system, permease component
Y_RS08900	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Y_RS08920	COG0668	transmembrane transport
Y_RS08925	COG1518	maintenance of DNA repeat elements
Y_RS08930	COG1203	CRISPR-associated helicase, Cas3
Y_RS08955	COG0667	Aldo Keto reductase
Y_RS08965	COG0477	Major facilitator Superfamily
Y_RS08975	COG0583	DNA-binding transcription factor activity
Y_RS08980	COG2771	luxR family
Y_RS08985	COG3916	Acyl-homoserine-lactone synthase
Y_RS09015	COG0628	permease
Y_RS09030	COG3328	transposase activity
Y_RS09035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Y_RS09060	COG3328	transposase activity
Y_RS09065	COG1530	ribonuclease E activity
Y_RS09070	COG0564	pseudouridine synthase activity
Y_RS09075	COG0424	maF-like protein
Y_RS09080	COG1399	metal-binding, possibly nucleic acid-binding protein
Y_RS09085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Y_RS09115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Y_RS09125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Y_RS09130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Y_RS09140	COG0470	DNA polymerase III
Y_RS09145	COG0084	hydrolase, TatD family'
Y_RS09150	COG1263	PTS System
Y_RS09150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Y_RS09160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Y_RS09165	COG0537	adenosine 5'-monophosphoramidase activity
Y_RS09170	COG5633	Lipoprotein
Y_RS09185	COG1472	Belongs to the glycosyl hydrolase 3 family
Y_RS09195	COG1252	NADH dehydrogenase
Y_RS09210	COG3328	transposase activity
Y_RS09215	COG3134	Outer membrane lipoprotein
Y_RS09220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Y_RS09225	COG4591	ABC-type transport system involved in lipoprotein release permease component
Y_RS09235	COG4591	ABC-type transport system involved in lipoprotein release permease component
Y_RS09240	COG1940	carbohydrate kinase activity
Y_RS09255	COG2850	peptidyl-arginine hydroxylation
Y_RS09265	COG0745	RESPONSE REGULATOR receiver
Y_RS09280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Y_RS09300	COG1187	pseudouridine synthase activity
Y_RS09305	COG0538	isocitrate dehydrogenase activity
Y_RS09320	COG0840	transmembrane signaling receptor activity
Y_RS09325	COG0702	epimerase
Y_RS09330	COG1733	regulation of RNA biosynthetic process
Y_RS09355	COG1522	sequence-specific DNA binding
Y_RS09365	COG0604	alcohol dehydrogenase
Y_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS09365	COG3321	synthase
Y_RS09395	COG1285	pathogenesis
Y_RS09420	COG1360	Flagellar Motor Protein
Y_RS09425	COG2198	Histidine kinase
Y_RS09425	COG0643	Histidine kinase
Y_RS09430	COG0835	chemotaxis
Y_RS09435	COG2271	Major facilitator Superfamily
Y_RS09440	COG0251	oxidation-reduction process
Y_RS09450	COG2964	Protein conserved in bacteria
Y_RS09470	COG0840	transmembrane signaling receptor activity
Y_RS09475	COG0840	transmembrane signaling receptor activity
Y_RS09480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Y_RS09490	COG0745	RESPONSE REGULATOR receiver
Y_RS09495	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Y_RS09505	COG3023	N-Acetylmuramoyl-L-alanine amidase
Y_RS09515	COG5295	Hep Hag repeat protein
Y_RS09525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Y_RS09580	COG3121	Chaperone
Y_RS09600	COG3008	intermembrane lipid transfer
Y_RS09605	COG2995	paraquat-inducible protein a
Y_RS09610	COG1956	GAF domain-containing protein
Y_RS09620	COG0793	Belongs to the peptidase S41A family
Y_RS09630	COG3539	Fimbrial protein
Y_RS09635	COG3121	Chaperone
Y_RS09650	COG3121	Chaperone
Y_RS09655	COG2814	Major facilitator Superfamily
Y_RS09660	COG0823	Involved in the tonB-independent uptake of proteins
Y_RS09670	COG3023	N-Acetylmuramoyl-L-alanine amidase
Y_RS09675	COG1823	symporter activity
Y_RS09680	COG1988	membrane-bound metal-dependent
Y_RS09685	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Y_RS09690	COG1653	transport
Y_RS09695	COG3842	ATPase activity
Y_RS09700	COG0395	ABC-type sugar transport system, permease component
Y_RS09705	COG1175	transmembrane transport
Y_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS09725	COG1917	Cupin 2, conserved barrel domain protein
Y_RS09730	COG3328	transposase activity
Y_RS09735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Y_RS09745	COG3001	Fructosamine kinase
Y_RS09755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Y_RS09760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Y_RS09765	COG1121	(ABC) transporter
Y_RS09770	COG0803	Belongs to the bacterial solute-binding protein 9 family
Y_RS09795	COG4249	Peptidase C14 caspase catalytic subunit p20
Y_RS09825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Y_RS09825	COG0072	phenylalanine-tRNA ligase activity
Y_RS09830	COG0776	regulation of translation
Y_RS09845	COG0386	Belongs to the glutathione peroxidase family
Y_RS09890	COG0791	NLP P60 protein
Y_RS09915	COG0574	Belongs to the PEP-utilizing enzyme family
Y_RS09915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Y_RS09920	COG0628	permease
Y_RS09925	COG0277	FAD linked oxidase domain protein
Y_RS09925	COG0247	lactate metabolic process
Y_RS09930	COG2050	protein possibly involved in aromatic compounds catabolism
Y_RS09940	COG0316	Belongs to the HesB IscA family
Y_RS09945	COG0719	Fe-S assembly protein
Y_RS09950	COG0396	ATPase activity
Y_RS09955	COG0719	Fe-S assembly protein
Y_RS09970	COG1388	LysM domain
Y_RS09970	COG1376	ErfK ybiS ycfS ynhG family protein
Y_RS10020	COG0307	riboflavin synthase, alpha
Y_RS10025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Y_RS10030	COG2814	Major facilitator Superfamily
Y_RS10035	COG0583	DNA-binding transcription factor activity
Y_RS10050	COG0791	NLP P60 protein
Y_RS10060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Y_RS10065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Y_RS10070	COG0346	lactoylglutathione lyase activity
Y_RS10075	COG1902	pentaerythritol trinitrate reductase activity
Y_RS10080	COG1309	transcriptional regulator
Y_RS10085	COG2194	sulfuric ester hydrolase activity
Y_RS10095	COG3133	Outer membrane lipoprotein
Y_RS10105	COG3895	Periplasmic Protein
Y_RS10125	COG0625	glutathione transferase activity
Y_RS10140	COG3104	oligopeptide transport
Y_RS10145	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Y_RS10145	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Y_RS10150	COG4172	Belongs to the ABC transporter superfamily
Y_RS10160	COG4171	peptide transport system, permease
Y_RS10165	COG4168	peptide transport system, permease
Y_RS10170	COG4166	transmembrane transport
Y_RS10190	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Y_RS10195	COG1842	Phage shock protein A
Y_RS10205	COG1983	PspC domain protein
Y_RS10215	COG3106	COG3106 Predicted ATPase
Y_RS10225	COG5654	RES domain protein
Y_RS10230	COG5642	Protein of unknown function (DUF2384)
Y_RS10245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Y_RS10250	COG4948	Mandelate Racemase Muconate Lactonizing
Y_RS10255	COG2866	Carboxypeptidase
Y_RS10260	COG4166	transmembrane transport
Y_RS10275	COG0657	acetylesterase activity
Y_RS10285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Y_RS10285	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Y_RS10285	COG1013	pyruvate-flavodoxin oxidoreductase activity
Y_RS10285	COG0674	pyruvate-flavodoxin oxidoreductase activity
Y_RS10295	COG1285	pathogenesis
Y_RS10300	COG3042	response to heat
Y_RS10305	COG3187	Heat shock protein
Y_RS10310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Y_RS10315	COG2911	Protein conserved in bacteria
Y_RS10325	COG3784	Protein of unknown function (DUF1318)
Y_RS10330	COG0246	Mannitol dehydrogenase
Y_RS10335	COG2390	Transcriptional regulator
Y_RS10345	COG1643	Atp-dependent helicase
Y_RS10360	COG3591	Belongs to the peptidase S1B family
Y_RS10410	COG1454	alcohol dehydrogenase
Y_RS10410	COG1012	belongs to the aldehyde dehydrogenase family
Y_RS10415	COG2095	MarC family integral membrane protein
Y_RS10425	COG0601	transmembrane transport
Y_RS10430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Y_RS10435	COG0444	Belongs to the ABC transporter superfamily
Y_RS10440	COG4608	Belongs to the ABC transporter superfamily
Y_RS10480	COG2350	Protein conserved in bacteria
Y_RS10485	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Y_RS10490	COG3328	transposase activity
Y_RS10525	COG3047	cAMP biosynthetic process
Y_RS10545	COG0134	indole-3-glycerol-phosphate synthase activity
Y_RS10545	COG0135	phosphoribosylanthranilate isomerase activity
Y_RS10555	COG0512	Glutamine amidotransferase of anthranilate synthase
Y_RS10580	COG0009	L-threonylcarbamoyladenylate synthase
Y_RS10585	COG1187	pseudouridine synthase activity
Y_RS10595	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS10600	COG0616	signal peptide processing
Y_RS10620	COG0583	DNA-binding transcription factor activity
Y_RS10630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Y_RS10640	COG0671	phosphoesterase, PA-phosphatase related
Y_RS10645	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
Y_RS10650	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Y_RS10665	COG0023	Translation Initiation Factor
Y_RS10685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Y_RS10690	COG2879	small protein
Y_RS10695	COG1966	Carbon starvation protein
Y_RS10705	COG2271	Major facilitator Superfamily
Y_RS10710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y_RS10715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Y_RS10725	COG4659	FMN binding
Y_RS10730	COG4658	electron transport chain
Y_RS10735	COG3708	Transcriptional regulator
Y_RS10735	COG2207	Transcriptional regulator
Y_RS10765	COG1132	(ABC) transporter
Y_RS10775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y_RS10780	COG2274	protein secretion by the type I secretion system
Y_RS10795	COG1879	ABC-type sugar transport system periplasmic component
Y_RS10800	COG1129	ABC transporter
Y_RS10805	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS10815	COG0673	inositol 2-dehydrogenase activity
Y_RS10820	COG0385	Bile acid
Y_RS10830	COG5339	Protein conserved in bacteria
Y_RS10840	COG0114	fumarate hydratase activity
Y_RS10855	COG0583	DNA-binding transcription factor activity
Y_RS10860	COG1940	carbohydrate kinase activity
Y_RS10865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Y_RS10870	COG0038	chloride channel
Y_RS10880	COG1609	Transcriptional regulator
Y_RS10900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y_RS10910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Y_RS10935	COG0028	Belongs to the TPP enzyme family
Y_RS10940	COG0440	acetolactate synthase activity
Y_RS10945	COG1011	Hydrolase
Y_RS10965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Y_RS10970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Y_RS10975	COG0589	response to stress
Y_RS10980	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Y_RS10985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Y_RS11000	COG0531	amino acid
Y_RS11010	COG0745	RESPONSE REGULATOR receiver
Y_RS11015	COG2205	protein histidine kinase activity
Y_RS11020	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Y_RS11055	COG0745	RESPONSE REGULATOR receiver
Y_RS11070	COG3328	transposase activity
Y_RS11080	COG0583	DNA-binding transcription factor activity
Y_RS11085	COG0708	Exodeoxyribonuclease III
Y_RS11090	COG0494	nUDIX hydrolase
Y_RS11100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Y_RS11105	COG0709	Synthesizes selenophosphate from selenide and ATP
Y_RS11110	COG0778	Nitroreductase
Y_RS11115	COG0616	signal peptide processing
Y_RS11120	COG0252	asparaginase activity
Y_RS11125	COG1335	isochorismatase
Y_RS11130	COG3139	Protein of unknown function (DUF1315)
Y_RS11150	COG3713	MltA-interacting MipA family protein
Y_RS11155	COG2766	serine protein kinase
Y_RS11170	COG0583	DNA-binding transcription factor activity
Y_RS11180	COG2814	Major facilitator Superfamily
Y_RS11190	COG2719	SpoVR family
Y_RS11220	COG1104	cysteine desulfurase activity
Y_RS11230	COG3328	transposase activity
Y_RS11395	COG3328	transposase activity
Y_RS11495	COG0582	viral genome integration into host DNA
Y_RS11505	COG0179	Fumarylacetoacetate (FAA) hydrolase
Y_RS11510	COG2951	lytic endotransglycosylase activity
Y_RS11525	COG2894	cell division
Y_RS11530	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Y_RS11535	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Y_RS11540	COG0318	PFAM AMP-dependent synthetase and ligase
Y_RS11545	COG3065	identical protein binding
Y_RS11555	COG1199	ATP-dependent helicase activity
Y_RS11560	COG0251	oxidation-reduction process
Y_RS11575	COG0800	Aldolase
Y_RS11580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Y_RS11585	COG1737	Transcriptional regulator
Y_RS11590	COG0469	pyruvate kinase activity
Y_RS11595	COG1560	Kdo2-lipid A biosynthetic process
Y_RS11600	COG0739	heme binding
Y_RS11605	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Y_RS11615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Y_RS11640	COG0494	nUDIX hydrolase
Y_RS11650	COG1801	Protein of unknown function DUF72
Y_RS11655	COG3788	relative of glutathione S-transferase, MAPEG superfamily
Y_RS11675	COG3102	Protein conserved in bacteria
Y_RS11695	COG0728	peptidoglycan biosynthetic process
Y_RS11700	COG0673	inositol 2-dehydrogenase activity
Y_RS11705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Y_RS11720	COG3381	protein complex oligomerization
Y_RS11735	COG1940	carbohydrate kinase activity
Y_RS11740	COG0584	glycerophosphoryl diester phosphodiesterase
Y_RS11745	COG3842	ATPase activity
Y_RS11760	COG1176	ABC-type spermidine putrescine transport system, permease component I
Y_RS11765	COG3833	ABC-type maltose transport systems, permease component
Y_RS11790	COG0659	secondary active sulfate transmembrane transporter activity
Y_RS11810	COG2890	protein-(glutamine-N5) methyltransferase activity
Y_RS11840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Y_RS11860	COG0012	GTP binding
Y_RS11915	COG5002	protein histidine kinase activity
Y_RS11955	COG0500	methyltransferase
Y_RS11980	COG3328	transposase activity
Y_RS12025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y_RS12030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Y_RS12035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Y_RS12050	COG0402	S-adenosylhomocysteine deaminase activity
Y_RS12115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Y_RS12120	COG3850	Histidine kinase
Y_RS12125	COG0387	Pfam Sodium calcium exchanger
Y_RS12130	COG1702	phosphate starvation-inducible protein PhoH
Y_RS12145	COG3658	cytochrome
Y_RS12150	COG1215	transferase activity, transferring glycosyl groups
Y_RS12155	COG0726	polysaccharide deacetylase
Y_RS12155	COG1649	PFAM Uncharacterised BCR, COG1649
Y_RS12160	COG0457	Tetratricopeptide repeat
Y_RS12165	COG0006	proline dipeptidase activity
Y_RS12185	COG0577	efflux transmembrane transporter activity
Y_RS12185	COG1136	(ABC) transporter
Y_RS12195	COG0577	efflux transmembrane transporter activity
Y_RS12195	COG1136	(ABC) transporter
Y_RS12210	COG0672	)-iron permease
Y_RS12220	COG2066	Belongs to the glutaminase family
Y_RS12225	COG1349	DNA-binding transcription factor activity
Y_RS12235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Y_RS12240	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Y_RS12255	COG2814	Major facilitator Superfamily
Y_RS12280	COG2030	dehydratase
Y_RS12285	COG0427	acetyl-CoA hydrolase
Y_RS12295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y_RS12295	COG2205	protein histidine kinase activity
Y_RS12310	COG3188	usher protein
Y_RS12320	COG3121	Chaperone
Y_RS12330	COG0582	viral genome integration into host DNA
Y_RS12335	COG1169	isochorismate synthase
Y_RS12340	COG2814	Major facilitator Superfamily
Y_RS12345	COG1132	(ABC) transporter
Y_RS12360	COG3433	isochorismatase activity
Y_RS12360	COG2226	methyltransferase
Y_RS12360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Y_RS12380	COG1021	2,3-dihydroxybenzoate-AMP ligase
Y_RS12385	COG4771	TonB-dependent receptor
Y_RS12460	COG3842	ATPase activity
Y_RS12465	COG0395	ABC-type sugar transport system, permease component
Y_RS12470	COG1175	transmembrane transport
Y_RS12480	COG0673	inositol 2-dehydrogenase activity
Y_RS12490	COG2188	Transcriptional regulator
Y_RS12635	COG2197	response regulator
Y_RS12645	COG3136	membrane protein required for alginate biosynthesis
Y_RS12665	COG1113	amino acid transport
Y_RS12685	COG2822	iron ion transport
Y_RS12690	COG0672	)-iron permease
Y_RS12705	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Y_RS12705	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Y_RS12705	COG0506	proline dehydrogenase activity
Y_RS12720	COG1126	abc transporter atp-binding protein
Y_RS12725	COG0765	amino acid transport
Y_RS12730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y_RS12745	COG1191	sigma factor activity
Y_RS12780	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Y_RS12785	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Y_RS12790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Y_RS12805	COG1677	Flagellar hook-basal body complex protein FliE
Y_RS12825	COG1157	protein secretion by the type III secretion system
Y_RS12840	COG1580	Controls the rotational direction of flagella during chemotaxis
Y_RS12865	COG1987	bacterial-type flagellum assembly
Y_RS12885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y_RS12890	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS12895	COG1129	ABC transporter
Y_RS12905	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS12910	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS12910	COG3347	Dehydrogenase
Y_RS12915	COG2390	Transcriptional regulator
Y_RS12925	COG1256	bacterial-type flagellum assembly
Y_RS12965	COG1558	bacterial-type flagellum-dependent cell motility
Y_RS12970	COG1815	bacterial-type flagellum-dependent cell motility
Y_RS12980	COG2747	anti-sigma28 factor FlgM
Y_RS12985	COG3418	PFAM FlgN family protein
Y_RS13010	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Y_RS13015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Y_RS13045	COG2372	response to copper ion
Y_RS13050	COG1528	Iron-storage protein
Y_RS13065	COG1770	oligopeptidase
Y_RS13080	COG3141	response to X-ray
Y_RS13085	COG0513	Belongs to the DEAD box helicase family
Y_RS13110	COG1760	l-serine dehydratase
Y_RS13115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Y_RS13120	COG2368	4-hydroxyphenylacetate
Y_RS13135	COG3971	2-oxopent-4-enoate hydratase activity
Y_RS13145	COG3384	dioxygenase
Y_RS13150	COG1012	belongs to the aldehyde dehydrogenase family
Y_RS13165	COG1846	Transcriptional regulator
Y_RS13170	COG1253	flavin adenine dinucleotide binding
Y_RS13175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y_RS13175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Y_RS13180	COG3715	PTS system
Y_RS13185	COG3716	PTS system mannose fructose sorbose family IID component
Y_RS13215	COG2226	methyltransferase
Y_RS13220	COG1496	oxidoreductase activity
Y_RS13245	COG1113	amino acid transport
Y_RS13280	COG2207	Transcriptional regulator
Y_RS13290	COG1132	(ABC) transporter
Y_RS13335	COG3328	transposase activity
Y_RS13340	COG2223	nitrite transmembrane transporter activity
Y_RS13360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Y_RS13385	COG3122	Protein conserved in bacteria
Y_RS13405	COG0534	Mate efflux family protein
Y_RS13420	COG4948	Mandelate Racemase Muconate Lactonizing
Y_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS13435	COG3011	Protein conserved in bacteria
Y_RS13440	COG2271	Major facilitator Superfamily
Y_RS13445	COG1470	cell adhesion involved in biofilm formation
Y_RS13445	COG1388	LysM domain
Y_RS13450	COG3328	transposase activity
Y_RS13465	COG2925	Exonuclease
Y_RS13470	COG0531	amino acid
Y_RS13480	COG0371	Dehydrogenase
Y_RS13485	COG1129	ABC transporter
Y_RS13490	COG1129	ABC transporter
Y_RS13495	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS13505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y_RS13515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Y_RS13525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Y_RS13525	COG0131	Imidazoleglycerol-phosphate dehydratase
Y_RS13545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Y_RS13545	COG0140	phosphoribosyl-ATP diphosphatase activity
Y_RS13555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Y_RS13560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Y_RS13575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Y_RS13580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y_RS13585	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y_RS13590	COG1120	ATPase activity
Y_RS13605	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Y_RS13610	COG0076	glutamate decarboxylase activity
Y_RS13615	COG4114	ferric iron reductase
Y_RS13620	COG1253	flavin adenine dinucleotide binding
Y_RS13625	COG2982	Protein involved in outer membrane biogenesis
Y_RS13640	COG0489	protein tyrosine kinase activity
Y_RS13675	COG2814	Major facilitator Superfamily
Y_RS13685	COG1346	cytolysis
Y_RS13700	COG2949	membrane
Y_RS13705	COG4211	Belongs to the binding-protein-dependent transport system permease family
Y_RS13720	COG2311	Membrane
Y_RS13730	COG0477	Major facilitator Superfamily
Y_RS13735	COG0583	DNA-binding transcription factor activity
Y_RS13770	COG1136	(ABC) transporter
Y_RS13780	COG0303	'Molybdopterin
Y_RS13790	COG3328	transposase activity
Y_RS13800	COG0488	(ABC) transporter
Y_RS13935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Y_RS13940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Y_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS13955	COG1024	Enoyl-CoA hydratase
Y_RS13965	COG3425	synthase
Y_RS13970	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS13975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Y_RS13980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Y_RS13990	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS14025	COG2920	part of a sulfur-relay system
Y_RS14045	COG1832	CoA-binding protein
Y_RS14060	COG0210	DNA helicase
Y_RS14065	COG3304	Inner membrane component domain
Y_RS14070	COG1289	transmembrane transporter activity
Y_RS14075	COG3070	regulator of competence-specific genes
Y_RS14105	COG1067	ATP-dependent peptidase activity
Y_RS14120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Y_RS14135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Y_RS14150	COG3130	regulation of translation
Y_RS14160	COG3009	Protein conserved in bacteria
Y_RS14165	COG3008	intermembrane lipid transfer
Y_RS14165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Y_RS14170	COG2995	paraquat-inducible protein a
Y_RS14175	COG0488	(ABC) transporter
Y_RS14185	COG3217	Mosc domain protein beta barrel domain protein
Y_RS14185	COG0633	Ferredoxin
Y_RS14200	COG0308	aminopeptidase N
Y_RS14220	COG1448	Aminotransferase
Y_RS14225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Y_RS14230	COG3108	Peptidase M15
Y_RS14235	COG2989	Protein conserved in bacteria
Y_RS14265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Y_RS14275	COG3173	Aminoglycoside phosphotransferase
Y_RS14290	COG1278	Cold shock
Y_RS14295	COG5383	Protein conserved in bacteria
Y_RS14310	COG0658	competence protein
Y_RS14310	COG2333	competence protein COMEC
Y_RS14320	COG0539	negative regulation of cytoplasmic translation
Y_RS14345	COG5295	Hep Hag repeat protein
Y_RS14345	COG5295	Hep Hag repeat protein
Y_RS14350	COG0252	asparaginase activity
Y_RS14355	COG1944	ATP diphosphatase activity
Y_RS14360	COG2116	formate transmembrane transporter activity
Y_RS14365	COG1882	Formate acetyltransferase
Y_RS14375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Y_RS14405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Y_RS14415	COG3107	peptidoglycan biosynthetic process
Y_RS14415	COG1674	ftsk spoiiie
Y_RS14425	COG0492	ferredoxin-NADP+ reductase activity
Y_RS14440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Y_RS14450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Y_RS14460	COG0542	response to heat
Y_RS14470	COG1278	Cold shock
Y_RS14480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y_RS14490	COG2990	Protein conserved in bacteria
Y_RS14495	COG3593	DNA synthesis involved in DNA repair
Y_RS14500	COG2431	L-lysine efflux transmembrane transporter activity
Y_RS14510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Y_RS14515	COG0028	Belongs to the TPP enzyme family
Y_RS14520	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Y_RS14525	COG0702	epimerase
Y_RS14530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Y_RS14540	COG1605	Chorismate mutase
Y_RS14545	COG1126	abc transporter atp-binding protein
Y_RS14550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y_RS14555	COG4215	(ABC) transporter
Y_RS14560	COG4160	amino acid transport
Y_RS14585	COG1120	ATPase activity
Y_RS14615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y_RS14630	COG1177	transmembrane transport
Y_RS14635	COG1176	ABC-type spermidine putrescine transport system, permease component I
Y_RS14640	COG3842	ATPase activity
Y_RS14645	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Y_RS14680	COG0671	phosphoesterase, PA-phosphatase related
Y_RS14690	COG1349	DNA-binding transcription factor activity
Y_RS14695	COG0814	amino acid
Y_RS14705	COG1686	Belongs to the peptidase S11 family
Y_RS14710	COG2011	ABC-type metal ion transport system permease component
Y_RS14735	COG0625	glutathione transferase activity
Y_RS14740	COG4771	TonB-dependent receptor
Y_RS14750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Y_RS14760	COG0833	amino acid
Y_RS14765	COG0583	DNA-binding transcription factor activity
Y_RS14770	COG2855	membrane
Y_RS14780	COG3188	usher protein
Y_RS14785	COG3121	Chaperone
Y_RS14800	COG3710	Transcriptional regulator
Y_RS14805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Y_RS14805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Y_RS14805	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Y_RS14810	COG1105	Belongs to the carbohydrate kinase PfkB family
Y_RS14820	COG0494	nUDIX hydrolase
Y_RS14830	COG1129	ABC transporter
Y_RS14865	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS14890	COG0246	Mannitol dehydrogenase
Y_RS14895	COG2186	Transcriptional regulator
Y_RS14905	COG0523	cobalamin synthesis protein
Y_RS14910	COG0671	phosphoesterase, PA-phosphatase related
Y_RS14915	COG0791	NLP P60 protein
Y_RS14920	COG2200	EAL domain
Y_RS14925	COG4166	transmembrane transport
Y_RS14930	COG4174	ABC transporter (Permease)
Y_RS14935	COG4239	(ABC) transporter, permease
Y_RS14940	COG4172	Belongs to the ABC transporter superfamily
Y_RS14950	COG2814	Major facilitator Superfamily
Y_RS14955	COG1187	pseudouridine synthase activity
Y_RS14960	COG1061	Type III restriction enzyme res subunit
Y_RS14980	COG3082	Protein of unknown function (DUF1414)
Y_RS14985	COG3083	sulfuric ester hydrolase activity
Y_RS15005	COG3157	Type VI secretion system effector, Hcp
Y_RS15025	COG2723	6-phospho-beta-galactosidase activity
Y_RS15030	COG1737	Transcriptional regulator
Y_RS15050	COG3299	homolog of phage Mu protein gp47
Y_RS15090	COG4386	tail sheath protein
Y_RS15110	COG3622	Belongs to the hyi family
Y_RS15115	COG1349	DNA-binding transcription factor activity
Y_RS15125	COG3395	kinase activity
Y_RS15170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Y_RS15200	COG2223	nitrite transmembrane transporter activity
Y_RS15205	COG2198	Histidine kinase
Y_RS15205	COG0642	Histidine kinase
Y_RS15210	COG2198	Histidine kinase
Y_RS15210	COG0642	Histidine kinase
Y_RS15220	COG0784	Response regulator, receiver
Y_RS15220	COG2205	protein histidine kinase activity
Y_RS15250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Y_RS15265	COG0814	amino acid
Y_RS15290	COG0697	spore germination
Y_RS15300	COG1982	Orn Lys Arg decarboxylase major
Y_RS15305	COG0531	amino acid
Y_RS15310	COG1174	glycine betaine transport
Y_RS15315	COG1125	glycine betaine transport
Y_RS15320	COG1174	glycine betaine transport
Y_RS15325	COG1732	Glycine betaine
Y_RS15330	COG1732	Glycine betaine
Y_RS15335	COG2897	thiosulfate sulfurtransferase activity
Y_RS15355	COG1122	ATPase activity
Y_RS15375	COG4807	Protein conserved in bacteria
Y_RS15390	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Y_RS15400	COG2261	transglycosylase associated protein
Y_RS15420	COG0277	FAD linked oxidase domain protein
Y_RS15425	COG1686	Belongs to the peptidase S11 family
Y_RS15435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Y_RS15455	COG0670	Belongs to the BI1 family
Y_RS15460	COG0314	molybdopterin synthase activity
Y_RS15465	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Y_RS15475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Y_RS15485	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Y_RS15490	COG4628	conserved protein (DUF2132)
Y_RS15500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Y_RS15510	COG2226	methyltransferase
Y_RS15535	COG0561	phosphatase activity
Y_RS15545	COG4149	molybdate abc transporter
Y_RS15550	COG0725	ABC transporter, periplasmic molybdate-binding protein
Y_RS15560	COG2005	Transcriptional regulator
Y_RS15560	COG3585	molybdate ion transport
Y_RS15565	COG1119	ATPase activity
Y_RS15580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Y_RS15585	COG1085	galactose-1-phosphate uridylyltransferase
Y_RS15600	COG2017	converts alpha-aldose to the beta-anomer
Y_RS15615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Y_RS15620	COG1230	cation diffusion facilitator family transporter
Y_RS15650	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Y_RS15655	COG2885	chlorophyll binding
Y_RS15665	COG3064	Membrane
Y_RS15665	COG3064	Membrane
Y_RS15670	COG0848	biopolymer transport protein
Y_RS15675	COG0811	peptide transport
Y_RS15680	COG0824	Thioesterase
Y_RS15685	COG3790	cyd operon protein YbgE
Y_RS15690	COG4890	Cyd operon protein YbgT
Y_RS15695	COG1294	oxidase, subunit
Y_RS15700	COG1271	oxidase subunit
Y_RS15705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Y_RS15715	COG0508	dehydrogenase complex catalyzes the overall conversion of
Y_RS15720	COG0567	Dehydrogenase, E1 component
Y_RS15730	COG1053	succinate dehydrogenase
Y_RS15735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Y_RS15740	COG2009	succinate dehydrogenase
Y_RS15755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Y_RS15760	COG0497	DNA recombination
Y_RS15765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Y_RS15775	COG2867	negative regulation of translational initiation
Y_RS15795	COG0582	viral genome integration into host DNA
Y_RS15855	COG3657	addiction module killer protein
Y_RS15885	COG1953	Uracil, thiamine, allantoin
Y_RS15905	COG2226	methyltransferase
Y_RS15910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Y_RS15915	COG1388	LysM domain
Y_RS15915	COG0741	lytic transglycosylase activity
Y_RS15930	COG0656	L-ascorbic acid biosynthetic process
Y_RS15965	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Y_RS15975	COG2011	ABC-type metal ion transport system permease component
Y_RS15980	COG1464	Belongs to the NlpA lipoprotein family
Y_RS15990	COG1720	tRNA m6t6A37 methyltransferase activity
Y_RS16000	COG3015	lipoprotein NlpE involved in copper resistance
Y_RS16010	COG4681	YaeQ
Y_RS16020	COG4568	rho-dependent transcription termination
Y_RS16030	COG0037	tRNA processing
Y_RS16035	COG0346	lactoylglutathione lyase activity
Y_RS16045	COG0587	DNA-directed DNA polymerase activity
Y_RS16070	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Y_RS16085	COG0750	zinc metalloprotease
Y_RS16090	COG0575	Belongs to the CDS family
Y_RS16150	COG0564	pseudouridine synthase activity
Y_RS16155	COG3098	single-species biofilm formation
Y_RS16175	COG1611	Belongs to the LOG family
Y_RS16200	COG2363	Small membrane protein
Y_RS16205	COG0583	DNA-binding transcription factor activity
Y_RS16210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Y_RS16215	COG2166	iron-sulfur cluster assembly
Y_RS16220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Y_RS16225	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Y_RS16240	COG0860	N-Acetylmuramoyl-L-alanine amidase
Y_RS16250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Y_RS16255	COG1074	ATP-dependent DNA helicase activity
Y_RS16265	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Y_RS16330	COG0667	Aldo Keto reductase
Y_RS16360	COG1609	Transcriptional regulator
Y_RS16370	COG0583	DNA-binding transcription factor activity
Y_RS16375	COG2814	Major facilitator Superfamily
Y_RS16380	COG0583	DNA-binding transcription factor activity
Y_RS16395	COG0840	transmembrane signaling receptor activity
Y_RS16465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Y_RS16485	COG0288	reversible hydration of carbon dioxide
Y_RS16530	COG3119	arylsulfatase activity
Y_RS16535	COG1349	DNA-binding transcription factor activity
Y_RS16545	COG2222	sugar isomerase
Y_RS16550	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Y_RS16555	COG3715	PTS system
Y_RS16565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y_RS16575	COG1028	Short-chain dehydrogenase reductase Sdr
Y_RS16585	COG0641	radical SAM
Y_RS16590	COG3119	arylsulfatase activity
Y_RS16620	COG2271	Major facilitator Superfamily
Y_RS16640	COG1263	PTS System
Y_RS16640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Y_RS16645	COG1874	Beta-galactosidase
Y_RS16650	COG3867	Arabinogalactan endo-beta-1,4-galactanase
Y_RS16655	COG3833	ABC-type maltose transport systems, permease component
Y_RS16660	COG1175	transmembrane transport
Y_RS16665	COG2182	Extracellular solute-binding protein
Y_RS16675	COG1129	ABC transporter
Y_RS16680	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS16685	COG1879	ABC-type sugar transport system periplasmic component
Y_RS16695	COG0791	NLP P60 protein
Y_RS16700	COG1695	Transcriptional regulator
Y_RS16795	COG2944	sequence-specific DNA binding
Y_RS16825	COG0582	viral genome integration into host DNA
Y_RS16845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Y_RS16850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Y_RS16855	COG4974	Belongs to the 'phage' integrase family
Y_RS16860	COG0716	FMN binding
Y_RS16865	COG4452	Inner membrane protein CreD
Y_RS16870	COG2205	protein histidine kinase activity
Y_RS16875	COG0745	RESPONSE REGULATOR receiver
Y_RS16900	COG1272	protein, Hemolysin III
Y_RS16910	COG5295	Hep Hag repeat protein
Y_RS16940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Y_RS16945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Y_RS16950	COG0006	proline dipeptidase activity
Y_RS16965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Y_RS16970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Y_RS17005	COG0191	fructose-bisphosphate aldolase activity
Y_RS17025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Y_RS17030	COG0501	Belongs to the peptidase M48B family
Y_RS17040	COG1166	arginine decarboxylase activity
Y_RS17055	COG2356	endonuclease I
Y_RS17060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Y_RS17065	COG0189	ligase activity
Y_RS17080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Y_RS17090	COG2805	Type II/IV secretion system protein
Y_RS17095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Y_RS17100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Y_RS17105	COG0762	integral membrane protein
Y_RS17115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Y_RS17120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Y_RS17125	COG1073	alpha beta
Y_RS17125	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Y_RS17125	COG3064	Membrane
Y_RS17145	COG3171	Protein conserved in bacteria
Y_RS17155	COG1194	a g-specific adenine glycosylase
Y_RS17175	COG4774	siderophore transport
Y_RS17180	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS17185	COG1129	ABC transporter
Y_RS17190	COG1879	ABC-type sugar transport system periplasmic component
Y_RS17195	COG1982	Orn Lys Arg decarboxylase major
Y_RS17330	COG3916	Acyl-homoserine-lactone synthase
Y_RS17335	COG2771	luxR family
Y_RS17385	COG2211	Major facilitator Superfamily
Y_RS17395	COG2801	Transposase and inactivated derivatives
Y_RS17400	COG5001	Diguanylate cyclase
Y_RS17410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y_RS17450	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Y_RS17455	COG2195	Cleaves the N-terminal amino acid of tripeptides
Y_RS17460	COG4771	TonB-dependent receptor
Y_RS17490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Y_RS17490	COG2226	methyltransferase
Y_RS17490	COG3433	isochorismatase activity
Y_RS17515	COG1132	(ABC) transporter
Y_RS17515	COG2375	cellular response to nickel ion
Y_RS17520	COG1132	(ABC) transporter
Y_RS17535	COG2610	gluconate transmembrane transporter activity
Y_RS17555	COG3501	Rhs element vgr protein
Y_RS17580	COG0471	metal ion transport
Y_RS17595	COG2801	Transposase and inactivated derivatives
Y_RS17610	COG3710	Transcriptional regulator
Y_RS17630	COG1256	bacterial-type flagellum assembly
Y_RS17640	COG1706	bacterial-type flagellum-dependent cell motility
Y_RS17650	COG4786	Flagellar basal body rod
Y_RS17655	COG4787	bacterial-type flagellum-dependent cell motility
Y_RS17660	COG1749	Flagellar hook protein flgE
Y_RS17665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Y_RS17670	COG1558	bacterial-type flagellum-dependent cell motility
Y_RS17675	COG1815	bacterial-type flagellum-dependent cell motility
Y_RS17680	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
Y_RS17720	COG1677	Flagellar hook-basal body complex protein FliE
Y_RS17745	COG1987	bacterial-type flagellum assembly
Y_RS17750	COG1684	flagellar biosynthetic protein fliR
Y_RS17755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Y_RS17775	COG4592	Periplasmic binding protein
Y_RS17810	COG4964	Belongs to the GSP D family
Y_RS17815	COG4964	Belongs to the GSP D family
Y_RS17865	COG0848	biopolymer transport protein
Y_RS17870	COG0811	peptide transport
Y_RS17875	COG0626	cystathionine gamma-synthase activity
Y_RS17880	COG0586	Pfam SNARE associated Golgi protein
Y_RS17885	COG2207	Transcriptional regulator
Y_RS17890	COG1979	alcohol dehydrogenase
Y_RS17900	COG0656	L-ascorbic acid biosynthetic process
Y_RS17910	COG2132	Multicopper oxidase
Y_RS17920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Y_RS17930	COG2249	NAD(P)H dehydrogenase (quinone) activity
Y_RS17935	COG0583	DNA-binding transcription factor activity
Y_RS17945	COG3150	esterase
Y_RS17950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Y_RS17955	COG3151	Protein conserved in bacteria
Y_RS17960	COG0494	nUDIX hydrolase
Y_RS17965	COG1538	Outer membrane efflux protein
Y_RS17980	COG0754	glutathionylspermidine amidase activity
Y_RS17985	COG3384	dioxygenase
Y_RS18005	COG0531	amino acid
Y_RS18020	COG3025	triphosphatase activity
Y_RS18025	COG4991	sh3 domain protein
Y_RS18040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Y_RS18055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Y_RS18060	COG0358	DNA primase activity
Y_RS18145	COG0251	oxidation-reduction process
Y_RS18165	COG0436	Aminotransferase
Y_RS18190	COG1289	transmembrane transporter activity
Y_RS18210	COG0395	ABC-type sugar transport system, permease component
Y_RS18220	COG2182	Extracellular solute-binding protein
Y_RS18225	COG1609	Transcriptional regulator
Y_RS18230	COG3459	Glycosyltransferase 36 associated
Y_RS18235	COG3842	ATPase activity
Y_RS18255	COG3210	domain, Protein
Y_RS18280	COG3210	domain, Protein
Y_RS18285	COG2831	hemolysin activation secretion protein
Y_RS18290	COG4245	von Willebrand factor, type A
Y_RS18305	COG4245	von Willebrand factor, type A
Y_RS18325	COG3247	response to pH
Y_RS18330	COG1902	pentaerythritol trinitrate reductase activity
Y_RS18330	COG0446	pyridine nucleotide-disulphide oxidoreductase
Y_RS18345	COG1451	nucleotide metabolic process
Y_RS18350	COG0673	inositol 2-dehydrogenase activity
Y_RS18370	COG2721	sulfolactate sulfo-lyase activity
Y_RS18390	COG2271	Major facilitator Superfamily
Y_RS18405	COG0586	Pfam SNARE associated Golgi protein
Y_RS18425	COG4575	ribosome binding
Y_RS18430	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
Y_RS18440	COG2259	Doxx family
Y_RS18445	COG0435	Glutathione S-transferase
Y_RS18460	COG0494	nUDIX hydrolase
Y_RS18485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Y_RS18490	COG0849	cell division
Y_RS18495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Y_RS18515	COG0772	Belongs to the SEDS family
Y_RS18530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Y_RS18535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Y_RS18540	COG0768	penicillin binding
Y_RS18545	COG3116	cell division
Y_RS18565	COG1609	Transcriptional regulator
Y_RS18585	COG0028	Belongs to the TPP enzyme family
Y_RS18595	COG1022	Amp-dependent synthetase and ligase
Y_RS18630	COG0473	3-isopropylmalate dehydrogenase activity
Y_RS18645	COG2814	Major facilitator Superfamily
Y_RS18665	COG4143	(ABC) transporter
Y_RS18670	COG1178	ABC-type Fe3 transport system permease component
Y_RS18675	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Y_RS18680	COG0586	Pfam SNARE associated Golgi protein
Y_RS18685	COG0417	DNA replication proofreading
Y_RS18705	COG3047	cAMP biosynthetic process
Y_RS18705	COG2885	chlorophyll binding
Y_RS18790	COG0564	pseudouridine synthase activity
Y_RS18795	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Y_RS18850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Y_RS18860	COG2966	Psort location CytoplasmicMembrane, score
Y_RS18865	COG1280	lysine exporter protein (LysE YggA)
Y_RS18870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Y_RS18905	COG1047	Peptidyl-prolyl cis-trans
Y_RS18920	COG0196	riboflavin kinase activity
Y_RS18935	COG0583	DNA-binding transcription factor activity
Y_RS18955	COG1584	GPR1 FUN34 yaaH family protein
Y_RS18970	COG0521	Mo-molybdopterin cofactor biosynthetic process
Y_RS19000	COG0745	RESPONSE REGULATOR receiver
Y_RS19005	COG3045	CreA protein
Y_RS19010	COG3708	Transcriptional regulator
Y_RS19010	COG2207	Transcriptional regulator
Y_RS19025	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
Y_RS19030	COG0741	lytic transglycosylase activity
Y_RS19045	COG2199	diguanylate cyclase activity
Y_RS19050	COG2885	chlorophyll binding
Y_RS19070	COG0488	(ABC) transporter
Y_RS19090	COG0560	Phosphoserine phosphatase
Y_RS19095	COG3726	membrane protein affecting hemolysin expression
Y_RS19125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Y_RS19130	COG0084	hydrolase, TatD family'
Y_RS19135	COG4667	esterase of the alpha-beta hydrolase superfamily
Y_RS19145	COG2823	Periplasmic or secreted lipoprotein
Y_RS19155	COG0456	acetyltransferase
Y_RS19160	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
Y_RS19205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Y_RS19210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Y_RS19230	COG0859	PFAM glycosyl transferase family 9
Y_RS19235	COG1070	Carbohydrate kinase
Y_RS19285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Y_RS19285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y_RS19285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y_RS19290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Y_RS19295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Y_RS19300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Y_RS19305	COG2207	Transcriptional regulator
Y_RS19315	COG4269	membrane
Y_RS19370	COG2963	transposase activity
Y_RS19385	COG1401	restriction endodeoxyribonuclease activity
Y_RS19410	COG1011	Hydrolase
Y_RS19425	COG0174	glutamine synthetase
Y_RS19430	COG3852	Histidine kinase
Y_RS19440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Y_RS19465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Y_RS19465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Y_RS19470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Y_RS19475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Y_RS19480	COG3084	Protein conserved in bacteria
Y_RS19490	COG1763	Mo-molybdopterin cofactor biosynthetic process
Y_RS19495	COG3328	transposase activity
Y_RS19540	COG2271	Major facilitator Superfamily
Y_RS19555	COG2831	hemolysin activation secretion protein
Y_RS19565	COG0747	negative chemotaxis
Y_RS19570	COG0601	transmembrane transport
Y_RS19575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Y_RS19580	COG0444	Belongs to the ABC transporter superfamily
Y_RS19585	COG4608	Belongs to the ABC transporter superfamily
Y_RS19590	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Y_RS19595	COG2199	diguanylate cyclase activity
Y_RS19595	COG2200	EAL domain
Y_RS19600	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Y_RS19620	COG0612	Peptidase, M16
Y_RS19625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Y_RS19630	COG1942	4-Oxalocrotonate Tautomerase
Y_RS19635	COG2200	EAL domain
Y_RS19640	COG2982	Protein involved in outer membrane biogenesis
Y_RS19645	COG2134	cdp-diacylglycerol pyrophosphatase
Y_RS19650	COG1295	ribonuclease BN
Y_RS19675	COG1929	Belongs to the glycerate kinase type-1 family
Y_RS19680	COG2610	gluconate transmembrane transporter activity
Y_RS19685	COG3835	regulator
Y_RS19690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Y_RS19695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Y_RS19700	COG0339	signal peptide processing
Y_RS19720	COG0589	response to stress
Y_RS19740	COG0306	phosphate transporter
Y_RS19745	COG2081	HI0933 family
Y_RS19760	COG1172	Belongs to the binding-protein-dependent transport system permease family
Y_RS19775	COG0191	fructose-bisphosphate aldolase activity
Y_RS19795	COG1741	Belongs to the pirin family
Y_RS19800	COG1609	Transcriptional regulator
Y_RS19805	COG2610	gluconate transmembrane transporter activity
Y_RS19810	COG3265	gluconokinase activity
Y_RS19830	COG2095	MarC family integral membrane protein
Y_RS19835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Y_RS19865	COG3275	phosphorelay sensor kinase activity
Y_RS19890	COG0058	SHG alpha-glucan phosphorylase activity
Y_RS19895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Y_RS19915	COG2801	Transposase and inactivated derivatives
Y_RS19925	COG1349	DNA-binding transcription factor activity
Y_RS19945	COG0058	SHG alpha-glucan phosphorylase activity
Y_RS19950	COG0058	SHG alpha-glucan phosphorylase activity
Y_RS19955	COG1640	4-alpha-glucanotransferase
Y_RS19990	COG1918	ferrous iron import across plasma membrane
Y_RS20000	COG2183	response to ionizing radiation
Y_RS20005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Y_RS20030	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Y_RS20035	COG1011	Hydrolase
Y_RS20050	COG0494	nUDIX hydrolase
Y_RS20055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Y_RS20085	COG4796	Type ii and iii secretion system protein
Y_RS20110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Y_RS20115	COG0546	phosphoglycolate phosphatase activity
Y_RS20120	COG0180	Tryptophanyl-tRNA synthetase
Y_RS20140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Y_RS20145	COG0402	S-adenosylhomocysteine deaminase activity
Y_RS20165	COG1486	melibiose metabolic process
Y_RS20170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Y_RS20175	COG0433	COG0433 Predicted ATPase
Y_RS20190	COG1289	transmembrane transporter activity
Y_RS20200	COG1765	OsmC-like protein
Y_RS20210	COG3954	Phosphoribulokinase
Y_RS20220	COG0429	hydrolase of the alpha beta-hydrolase fold
Y_RS20230	COG4521	taurine ABC transporter
Y_RS20240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Y_RS20245	COG2175	clavaminate synthase activity
Y_RS20255	COG1216	Glycosyl transferase, family 2
Y_RS20275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
Y_RS20280	COG1047	Peptidyl-prolyl cis-trans
Y_RS20290	COG0545	Peptidyl-prolyl cis-trans isomerase
Y_RS20295	COG2964	Protein conserved in bacteria
Y_RS20315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Y_RS20320	COG0049	tRNA binding
Y_RS20350	COG0051	transcription antitermination factor activity, RNA binding
Y_RS20365	COG0089	rRNA binding
Y_RS20375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Y_RS20385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Y_RS20390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Y_RS20400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Y_RS20405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Y_RS20445	COG1841	ribosomal large subunit assembly
Y_RS20455	COG0201	protein transport
Y_RS20460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Y_RS20475	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Y_RS20490	COG0789	Transcriptional regulator
Y_RS20495	COG3036	rescue of stalled ribosome
Y_RS20525	COG0758	DNA mediated transformation
Y_RS20535	COG0551	DNA topoisomerase type I activity
Y_RS20550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Y_RS20565	COG3851	Histidine kinase
Y_RS20570	COG2197	response regulator
Y_RS20575	COG2194	sulfuric ester hydrolase activity
Y_RS20595	COG2986	histidine ammonia-lyase
Y_RS20625	COG4607	ABC-type enterochelin transport system periplasmic component
Y_RS20635	COG4605	iron ion homeostasis
Y_RS20640	COG4604	ABC transporter, ATP-binding protein
Y_RS20680	COG0582	viral genome integration into host DNA
Y_RS20685	COG1609	Transcriptional regulator
Y_RS20685	COG2207	Transcriptional regulator
Y_RS20690	COG4214	carbohydrate transport
Y_RS20700	COG4213	ABC transporter substrate-binding protein
Y_RS20710	COG1070	Carbohydrate kinase
Y_RS20720	COG3121	Chaperone
Y_RS20740	COG3274	enterobacterial common antigen metabolic process
Y_RS20755	COG2801	Transposase and inactivated derivatives
Y_RS20790	COG3276	selenocysteine insertion sequence binding
Y_RS20805	COG2864	formate dehydrogenase
Y_RS20810	COG0437	4 iron, 4 sulfur cluster binding
Y_RS20815	COG3383	formate dehydrogenase (NAD+) activity
Y_RS20815	COG0243	molybdopterin cofactor binding
Y_RS20820	COG0243	molybdopterin cofactor binding
Y_RS20820	COG3383	formate dehydrogenase (NAD+) activity
Y_RS20830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Y_RS20855	COG3722	fumarate hydratase activity
Y_RS20865	COG2213	PTS system mannitol-specific
Y_RS20865	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y_RS20885	COG2818	Glycosylase
Y_RS20895	COG2885	chlorophyll binding
Y_RS20910	COG0366	Alpha amylase catalytic
Y_RS20920	COG3977	Valine--pyruvate aminotransferase
Y_RS20940	COG5645	(Lipo)protein
Y_RS20945	COG0823	Involved in the tonB-independent uptake of proteins
Y_RS20950	COG0823	Involved in the tonB-independent uptake of proteins
Y_RS20955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Y_RS20960	COG2423	ornithine cyclodeaminase activity
Y_RS20970	COG2801	Transposase and inactivated derivatives
Y_RS20975	COG0561	phosphatase activity
Y_RS20980	COG0187	DNA topoisomerase II activity
Y_RS20995	COG0592	DNA-directed DNA polymerase activity
Y_RS21005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Y_RS21015	COG0706	membrane insertase activity
Y_RS21040	COG2252	PERMEase
Y_RS21045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Y_RS21050	COG0765	amino acid transport
Y_RS21055	COG0765	amino acid transport
Y_RS21060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Y_RS21070	COG0704	Plays a role in the regulation of phosphate uptake
Y_RS21080	COG0581	inorganic phosphate transmembrane transporter activity
Y_RS21085	COG0573	inorganic phosphate transmembrane transporter activity
Y_RS21090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Y_RS21145	COG3312	ion transport
Y_RS21320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Y_RS21350	COG1410	methionine synthase
Y_RS21350	COG0646	methionine synthase
Y_RS21575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Y_RS21735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Y_RS21745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine