locus-tag	class	description
ISU62_RS00010	COG0592	DNA-directed DNA polymerase activity
ISU62_RS00025	COG0187	DNA topoisomerase II activity
ISU62_RS00030	COG0561	phosphatase activity
ISU62_RS00040	COG2423	ornithine cyclodeaminase activity
ISU62_RS00045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ISU62_RS00055	COG5645	(Lipo)protein
ISU62_RS00075	COG3977	Valine--pyruvate aminotransferase
ISU62_RS00085	COG0366	Alpha amylase catalytic
ISU62_RS00100	COG2885	chlorophyll binding
ISU62_RS00110	COG2818	Glycosylase
ISU62_RS00135	COG2213	PTS system mannitol-specific
ISU62_RS00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU62_RS00145	COG3722	fumarate hydratase activity
ISU62_RS00170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ISU62_RS00185	COG0437	4 iron, 4 sulfur cluster binding
ISU62_RS00190	COG2864	formate dehydrogenase
ISU62_RS00205	COG3276	selenocysteine insertion sequence binding
ISU62_RS00245	COG1349	DNA-binding transcription factor activity
ISU62_RS00265	COG0058	SHG alpha-glucan phosphorylase activity
ISU62_RS00270	COG0058	SHG alpha-glucan phosphorylase activity
ISU62_RS00275	COG1640	4-alpha-glucanotransferase
ISU62_RS00310	COG1918	ferrous iron import across plasma membrane
ISU62_RS00315	COG2183	response to ionizing radiation
ISU62_RS00320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU62_RS00345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ISU62_RS00350	COG1011	Hydrolase
ISU62_RS00360	COG0494	nUDIX hydrolase
ISU62_RS00365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ISU62_RS00390	COG4796	Type ii and iii secretion system protein
ISU62_RS00415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ISU62_RS00420	COG0546	phosphoglycolate phosphatase activity
ISU62_RS00425	COG0180	Tryptophanyl-tRNA synthetase
ISU62_RS00445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ISU62_RS00450	COG0402	S-adenosylhomocysteine deaminase activity
ISU62_RS00470	COG1486	melibiose metabolic process
ISU62_RS00475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU62_RS00480	COG0433	COG0433 Predicted ATPase
ISU62_RS00495	COG1289	transmembrane transporter activity
ISU62_RS00505	COG1765	OsmC-like protein
ISU62_RS00515	COG3954	Phosphoribulokinase
ISU62_RS00525	COG0429	hydrolase of the alpha beta-hydrolase fold
ISU62_RS00535	COG4521	taurine ABC transporter
ISU62_RS00545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU62_RS00550	COG2175	clavaminate synthase activity
ISU62_RS00560	COG1216	Glycosyl transferase, family 2
ISU62_RS00580	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ISU62_RS00585	COG1047	Peptidyl-prolyl cis-trans
ISU62_RS00595	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU62_RS00600	COG2964	Protein conserved in bacteria
ISU62_RS00620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ISU62_RS00625	COG0049	tRNA binding
ISU62_RS00665	COG0051	transcription antitermination factor activity, RNA binding
ISU62_RS00680	COG0089	rRNA binding
ISU62_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ISU62_RS00700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ISU62_RS00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ISU62_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ISU62_RS00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ISU62_RS00760	COG1841	ribosomal large subunit assembly
ISU62_RS00770	COG0201	protein transport
ISU62_RS00775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU62_RS00790	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ISU62_RS00805	COG0789	Transcriptional regulator
ISU62_RS00810	COG3036	rescue of stalled ribosome
ISU62_RS00840	COG0758	DNA mediated transformation
ISU62_RS00850	COG0551	DNA topoisomerase type I activity
ISU62_RS00865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISU62_RS00915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ISU62_RS00920	COG2224	Isocitrate lyase
ISU62_RS00950	COG0527	aspartate kinase activity
ISU62_RS00965	COG3833	ABC-type maltose transport systems, permease component
ISU62_RS00970	COG1175	transmembrane transport
ISU62_RS01100	COG3501	Rhs element vgr protein
ISU62_RS01145	COG3501	Rhs element vgr protein
ISU62_RS01175	COG0673	inositol 2-dehydrogenase activity
ISU62_RS01180	COG1917	Cupin 2, conserved barrel domain protein
ISU62_RS01180	COG2207	Transcriptional regulator
ISU62_RS01185	COG1869	D-ribose catabolic process
ISU62_RS01190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU62_RS01195	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ISU62_RS01200	COG0431	NADPH-dependent FMN reductase
ISU62_RS01205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISU62_RS01215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU62_RS01230	COG3077	Addiction module antitoxin, RelB DinJ family
ISU62_RS01235	COG2252	PERMEase
ISU62_RS01240	COG0025	NhaP-type Na H and K H
ISU62_RS01250	COG1560	Kdo2-lipid A biosynthetic process
ISU62_RS01260	COG1129	ABC transporter
ISU62_RS01265	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS01275	COG1069	ribulokinase activity
ISU62_RS01285	COG0625	glutathione transferase activity
ISU62_RS01305	COG1278	Cold shock
ISU62_RS01310	COG1278	Cold shock
ISU62_RS01315	COG3133	Outer membrane lipoprotein
ISU62_RS01320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU62_RS01330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU62_RS01360	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ISU62_RS01365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU62_RS01375	COG4145	pantothenate transmembrane transporter activity
ISU62_RS01380	COG3924	membrane
ISU62_RS01390	COG0439	Biotin carboxylase
ISU62_RS01395	COG0511	ligase activity, forming carbon-carbon bonds
ISU62_RS01410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ISU62_RS01415	COG0604	alcohol dehydrogenase
ISU62_RS01420	COG2200	EAL domain
ISU62_RS01420	COG2199	diguanylate cyclase activity
ISU62_RS01425	COG1077	Cell shape determining protein MreB Mrl
ISU62_RS01430	COG1792	Involved in formation and maintenance of cell shape
ISU62_RS01435	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ISU62_RS01440	COG0424	maF-like protein
ISU62_RS01445	COG1530	ribonuclease E activity
ISU62_RS01450	COG3164	Protein of unknown function
ISU62_RS01455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU62_RS01460	COG0312	modulator of DNA gyrase
ISU62_RS01510	COG0583	DNA-binding transcription factor activity
ISU62_RS01540	COG2732	(Barnase) inhibitor
ISU62_RS01550	COG0312	modulator of DNA gyrase
ISU62_RS01560	COG3783	Cytochrome b(562)
ISU62_RS01565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU62_RS01570	COG0366	Alpha amylase catalytic
ISU62_RS01575	COG1263	PTS System
ISU62_RS01575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU62_RS01580	COG1609	Transcriptional regulator
ISU62_RS01605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU62_RS01625	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ISU62_RS01630	COG1137	ATPase activity
ISU62_RS01635	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ISU62_RS01640	COG3117	lipopolysaccharide transmembrane transporter activity
ISU62_RS01645	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ISU62_RS01650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ISU62_RS01650	COG0517	IMP dehydrogenase activity
ISU62_RS01655	COG0530	calcium, potassium:sodium antiporter activity
ISU62_RS01660	COG1127	ABC transporter
ISU62_RS01665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ISU62_RS01670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU62_RS01675	COG2854	intermembrane phospholipid transfer
ISU62_RS01680	COG3113	response to antibiotic
ISU62_RS01685	COG5007	Belongs to the BolA IbaG family
ISU62_RS01695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU62_RS01705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU62_RS01710	COG3105	Protein conserved in bacteria
ISU62_RS01715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ISU62_RS01735	COG0625	glutathione transferase activity
ISU62_RS01740	COG2969	positive regulation of protein catabolic process
ISU62_RS01750	COG0493	'glutamate synthase
ISU62_RS01755	COG0070	glutamate synthase
ISU62_RS01755	COG0069	glutamate synthase activity
ISU62_RS01755	COG0067	glutamate synthase
ISU62_RS01760	COG1242	4 iron, 4 sulfur cluster binding
ISU62_RS01765	COG2198	Histidine kinase
ISU62_RS01765	COG5002	protein histidine kinase activity
ISU62_RS01765	COG0784	Response regulator, receiver
ISU62_RS01770	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ISU62_RS01780	COG2823	Periplasmic or secreted lipoprotein
ISU62_RS01800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ISU62_RS01810	COG1741	Belongs to the pirin family
ISU62_RS01815	COG0583	DNA-binding transcription factor activity
ISU62_RS01835	COG1401	restriction endodeoxyribonuclease activity
ISU62_RS01890	COG4269	membrane
ISU62_RS01900	COG2207	Transcriptional regulator
ISU62_RS01905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU62_RS01910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU62_RS01915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU62_RS01920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU62_RS01920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU62_RS01920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU62_RS01970	COG1070	Carbohydrate kinase
ISU62_RS01975	COG0859	PFAM glycosyl transferase family 9
ISU62_RS01990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU62_RS01995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU62_RS02035	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ISU62_RS02040	COG0456	acetyltransferase
ISU62_RS02050	COG2823	Periplasmic or secreted lipoprotein
ISU62_RS02060	COG4667	esterase of the alpha-beta hydrolase superfamily
ISU62_RS02065	COG0084	hydrolase, TatD family'
ISU62_RS02095	COG3726	membrane protein affecting hemolysin expression
ISU62_RS02100	COG0560	Phosphoserine phosphatase
ISU62_RS02125	COG2885	chlorophyll binding
ISU62_RS02130	COG2199	diguanylate cyclase activity
ISU62_RS02145	COG0741	lytic transglycosylase activity
ISU62_RS02150	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ISU62_RS02165	COG2207	Transcriptional regulator
ISU62_RS02165	COG3708	Transcriptional regulator
ISU62_RS02170	COG3045	CreA protein
ISU62_RS02175	COG0745	RESPONSE REGULATOR receiver
ISU62_RS02220	COG0521	Mo-molybdopterin cofactor biosynthetic process
ISU62_RS02235	COG1584	GPR1 FUN34 yaaH family protein
ISU62_RS02255	COG0583	DNA-binding transcription factor activity
ISU62_RS02265	COG0196	riboflavin kinase activity
ISU62_RS02280	COG1047	Peptidyl-prolyl cis-trans
ISU62_RS02305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISU62_RS02310	COG1280	lysine exporter protein (LysE YggA)
ISU62_RS02315	COG2966	Psort location CytoplasmicMembrane, score
ISU62_RS02325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ISU62_RS02375	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ISU62_RS02380	COG0564	pseudouridine synthase activity
ISU62_RS02475	COG3047	cAMP biosynthetic process
ISU62_RS02475	COG2885	chlorophyll binding
ISU62_RS02495	COG0417	DNA replication proofreading
ISU62_RS02500	COG0586	Pfam SNARE associated Golgi protein
ISU62_RS02505	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ISU62_RS02510	COG1178	ABC-type Fe3 transport system permease component
ISU62_RS02515	COG4143	(ABC) transporter
ISU62_RS02525	COG2814	Major facilitator Superfamily
ISU62_RS02540	COG0473	3-isopropylmalate dehydrogenase activity
ISU62_RS02565	COG1022	Amp-dependent synthetase and ligase
ISU62_RS02570	COG0028	Belongs to the TPP enzyme family
ISU62_RS02585	COG1609	Transcriptional regulator
ISU62_RS02610	COG3116	cell division
ISU62_RS02615	COG0768	penicillin binding
ISU62_RS02620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ISU62_RS02625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ISU62_RS02640	COG0772	Belongs to the SEDS family
ISU62_RS02660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ISU62_RS02665	COG0849	cell division
ISU62_RS02670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ISU62_RS02700	COG0494	nUDIX hydrolase
ISU62_RS02720	COG2259	Doxx family
ISU62_RS02730	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ISU62_RS02735	COG4575	ribosome binding
ISU62_RS02750	COG0586	Pfam SNARE associated Golgi protein
ISU62_RS02765	COG2271	Major facilitator Superfamily
ISU62_RS02785	COG2721	sulfolactate sulfo-lyase activity
ISU62_RS02805	COG0673	inositol 2-dehydrogenase activity
ISU62_RS02810	COG1451	nucleotide metabolic process
ISU62_RS02825	COG0446	pyridine nucleotide-disulphide oxidoreductase
ISU62_RS02825	COG1902	pentaerythritol trinitrate reductase activity
ISU62_RS02830	COG3247	response to pH
ISU62_RS02860	COG4245	von Willebrand factor, type A
ISU62_RS02865	COG2831	hemolysin activation secretion protein
ISU62_RS02870	COG3210	domain, Protein
ISU62_RS02900	COG3210	domain, Protein
ISU62_RS02905	COG3210	domain, Protein
ISU62_RS02925	COG3842	ATPase activity
ISU62_RS02930	COG3459	Glycosyltransferase 36 associated
ISU62_RS02935	COG1609	Transcriptional regulator
ISU62_RS02940	COG2182	Extracellular solute-binding protein
ISU62_RS02950	COG0395	ABC-type sugar transport system, permease component
ISU62_RS02970	COG1289	transmembrane transporter activity
ISU62_RS02990	COG0436	Aminotransferase
ISU62_RS03010	COG0251	oxidation-reduction process
ISU62_RS03080	COG0358	DNA primase activity
ISU62_RS03085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ISU62_RS03100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ISU62_RS03115	COG4991	sh3 domain protein
ISU62_RS03120	COG3025	triphosphatase activity
ISU62_RS03135	COG0531	amino acid
ISU62_RS03155	COG3384	dioxygenase
ISU62_RS03160	COG0754	glutathionylspermidine amidase activity
ISU62_RS03170	COG1538	Outer membrane efflux protein
ISU62_RS03175	COG0494	nUDIX hydrolase
ISU62_RS03180	COG3151	Protein conserved in bacteria
ISU62_RS03190	COG3150	esterase
ISU62_RS03200	COG0583	DNA-binding transcription factor activity
ISU62_RS03205	COG2249	NAD(P)H dehydrogenase (quinone) activity
ISU62_RS03215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ISU62_RS03225	COG2132	Multicopper oxidase
ISU62_RS03235	COG0656	L-ascorbic acid biosynthetic process
ISU62_RS03245	COG1979	alcohol dehydrogenase
ISU62_RS03250	COG2207	Transcriptional regulator
ISU62_RS03255	COG0586	Pfam SNARE associated Golgi protein
ISU62_RS03260	COG0626	cystathionine gamma-synthase activity
ISU62_RS03265	COG0811	peptide transport
ISU62_RS03270	COG0848	biopolymer transport protein
ISU62_RS03320	COG4964	Belongs to the GSP D family
ISU62_RS03325	COG4964	Belongs to the GSP D family
ISU62_RS03360	COG4592	Periplasmic binding protein
ISU62_RS03380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU62_RS03385	COG1684	flagellar biosynthetic protein fliR
ISU62_RS03390	COG1987	bacterial-type flagellum assembly
ISU62_RS03415	COG1677	Flagellar hook-basal body complex protein FliE
ISU62_RS03455	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ISU62_RS03460	COG1815	bacterial-type flagellum-dependent cell motility
ISU62_RS03465	COG1558	bacterial-type flagellum-dependent cell motility
ISU62_RS03470	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ISU62_RS03475	COG1749	Flagellar hook protein flgE
ISU62_RS03480	COG4787	bacterial-type flagellum-dependent cell motility
ISU62_RS03485	COG4786	Flagellar basal body rod
ISU62_RS03495	COG1706	bacterial-type flagellum-dependent cell motility
ISU62_RS03505	COG1256	bacterial-type flagellum assembly
ISU62_RS03525	COG3710	Transcriptional regulator
ISU62_RS03545	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ISU62_RS03570	COG1191	sigma factor activity
ISU62_RS03575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ISU62_RS03625	COG0471	metal ion transport
ISU62_RS03640	COG3209	COG3209 Rhs family protein
ISU62_RS03650	COG3501	Rhs element vgr protein
ISU62_RS03665	COG2610	gluconate transmembrane transporter activity
ISU62_RS03680	COG1132	(ABC) transporter
ISU62_RS03685	COG1132	(ABC) transporter
ISU62_RS03685	COG2375	cellular response to nickel ion
ISU62_RS03710	COG2226	methyltransferase
ISU62_RS03710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU62_RS03710	COG3433	isochorismatase activity
ISU62_RS03720	COG2226	methyltransferase
ISU62_RS03720	COG3433	isochorismatase activity
ISU62_RS03720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU62_RS03725	COG2226	methyltransferase
ISU62_RS03725	COG3433	isochorismatase activity
ISU62_RS03725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU62_RS03750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ISU62_RS03755	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU62_RS03760	COG0564	pseudouridine synthase activity
ISU62_RS03770	COG0542	response to heat
ISU62_RS03800	COG5544	Lipoprotein
ISU62_RS03805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ISU62_RS03810	COG0045	succinate-CoA ligase (ADP-forming) activity
ISU62_RS03810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU62_RS03810	COG1042	CoA-binding domain protein
ISU62_RS03815	COG3148	PFAM DTW domain containing protein
ISU62_RS03820	COG3118	belongs to the thioredoxin family
ISU62_RS03825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU62_RS03830	COG2814	Major facilitator Superfamily
ISU62_RS03835	COG1566	PFAM secretion protein HlyD family protein
ISU62_RS03840	COG1846	Transcriptional regulator
ISU62_RS03850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ISU62_RS03855	COG2814	Major facilitator Superfamily
ISU62_RS03890	COG0765	amino acid transport
ISU62_RS03900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU62_RS03915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU62_RS03940	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ISU62_RS03950	COG1960	acyl-CoA dehydrogenase activity
ISU62_RS03960	COG0121	glutamine amidotransferase
ISU62_RS03965	COG3034	peptidoglycan biosynthetic process
ISU62_RS03975	COG1805	sodium ion transport
ISU62_RS03980	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU62_RS04000	COG1477	protein flavinylation
ISU62_RS04020	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU62_RS04025	COG0583	DNA-binding transcription factor activity
ISU62_RS04075	COG2226	methyltransferase
ISU62_RS04100	COG1940	carbohydrate kinase activity
ISU62_RS04105	COG0419	ATPase involved in DNA repair
ISU62_RS04110	COG0420	3'-5' exonuclease activity
ISU62_RS04115	COG0745	RESPONSE REGULATOR receiver
ISU62_RS04120	COG5002	protein histidine kinase activity
ISU62_RS04140	COG0366	Alpha amylase catalytic
ISU62_RS04165	COG0450	alkyl hydroperoxide reductase
ISU62_RS04185	COG1862	Preprotein translocase
ISU62_RS04190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU62_RS04195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU62_RS04225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU62_RS04225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU62_RS04240	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ISU62_RS04245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ISU62_RS04260	COG0142	geranyltranstransferase activity
ISU62_RS04275	COG0693	protein deglycase activity
ISU62_RS04280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ISU62_RS04290	COG2814	Major facilitator Superfamily
ISU62_RS04300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ISU62_RS04305	COG1845	cytochrome c oxidase, subunit III
ISU62_RS04310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ISU62_RS04315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ISU62_RS04325	COG2223	nitrite transmembrane transporter activity
ISU62_RS04330	COG3056	Lipoprotein
ISU62_RS04335	COG0271	Belongs to the BolA IbaG family
ISU62_RS04355	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ISU62_RS04360	COG0776	regulation of translation
ISU62_RS04365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU62_RS04370	COG1555	photosystem II stabilization
ISU62_RS04375	COG0824	Thioesterase
ISU62_RS04385	COG4533	DNA binding
ISU62_RS04400	COG1522	sequence-specific DNA binding
ISU62_RS04405	COG1132	(ABC) transporter
ISU62_RS04410	COG1132	(ABC) transporter
ISU62_RS04415	COG0347	Belongs to the P(II) protein family
ISU62_RS04420	COG0004	ammonium transporteR
ISU62_RS04425	COG1946	Acyl-CoA thioesterase
ISU62_RS04430	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ISU62_RS04435	COG3695	enzyme binding
ISU62_RS04460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU62_RS04470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU62_RS04475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU62_RS04480	COG1309	transcriptional regulator
ISU62_RS04485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ISU62_RS04490	COG3264	Mechanosensitive ion channel
ISU62_RS04490	COG1196	nuclear chromosome segregation
ISU62_RS04505	COG2832	Protein of unknown function (DUF454)
ISU62_RS04515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ISU62_RS04545	COG0543	2 iron, 2 sulfur cluster binding
ISU62_RS04545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU62_RS04565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU62_RS04605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU62_RS04625	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU62_RS04630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU62_RS04635	COG4651	solute:proton antiporter activity
ISU62_RS04635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU62_RS04640	COG2223	nitrite transmembrane transporter activity
ISU62_RS04655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISU62_RS04660	COG3735	TraB family
ISU62_RS04665	COG2217	Heavy metal translocating P-type atpase
ISU62_RS04670	COG0789	Transcriptional regulator
ISU62_RS04675	COG1585	Membrane protein implicated in regulation of membrane protease activity
ISU62_RS04680	COG0330	HflC and HflK could
ISU62_RS04685	COG3118	belongs to the thioredoxin family
ISU62_RS04690	COG0300	oxidoreductase activity
ISU62_RS04695	COG2755	lipolytic protein G-D-S-L family
ISU62_RS04700	COG4181	ATPase activity
ISU62_RS04705	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ISU62_RS04710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ISU62_RS04715	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ISU62_RS04725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU62_RS04740	COG2501	S4 domain
ISU62_RS04775	COG0582	viral genome integration into host DNA
ISU62_RS04785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ISU62_RS04790	COG4589	Belongs to the CDS family
ISU62_RS04800	COG2267	carboxylic ester hydrolase activity
ISU62_RS04805	COG2453	phosphatase
ISU62_RS04805	COG0671	phosphoesterase, PA-phosphatase related
ISU62_RS04835	COG0667	Aldo Keto reductase
ISU62_RS04840	COG0656	L-ascorbic acid biosynthetic process
ISU62_RS04850	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU62_RS04865	COG3328	transposase activity
ISU62_RS04920	COG3423	Transcriptional regulator
ISU62_RS04925	COG4953	penicillin-binding protein 1C
ISU62_RS04935	COG2373	Large extracellular alpha-helical protein
ISU62_RS04955	COG3962	Belongs to the TPP enzyme family
ISU62_RS04970	COG1129	ABC transporter
ISU62_RS04975	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS04980	COG0673	inositol 2-dehydrogenase activity
ISU62_RS04985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU62_RS04995	COG3718	enzyme involved in inositol metabolism
ISU62_RS05005	COG5265	(ABC) transporter
ISU62_RS05030	COG2197	response regulator
ISU62_RS05035	COG1278	Cold shock
ISU62_RS05045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU62_RS05050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU62_RS05070	COG1686	Belongs to the peptidase S11 family
ISU62_RS05075	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU62_RS05080	COG0772	Belongs to the SEDS family
ISU62_RS05085	COG0768	penicillin binding
ISU62_RS05095	COG0799	negative regulation of ribosome biogenesis
ISU62_RS05105	COG1466	dna polymerase III delta subunit
ISU62_RS05120	COG2888	peptidyl-tyrosine sulfation
ISU62_RS05125	COG1126	abc transporter atp-binding protein
ISU62_RS05130	COG0765	amino acid transport
ISU62_RS05135	COG0765	amino acid transport
ISU62_RS05145	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ISU62_RS05150	COG4535	Mg2 and Co2 transporter CorC
ISU62_RS05160	COG1702	phosphate starvation-inducible protein PhoH
ISU62_RS05165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ISU62_RS05170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU62_RS05205	COG0367	asparagine synthase
ISU62_RS05210	COG0647	UMP catabolic process
ISU62_RS05215	COG1846	Transcriptional regulator
ISU62_RS05215	COG1940	carbohydrate kinase activity
ISU62_RS05220	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ISU62_RS05230	COG2190	(PTS) system
ISU62_RS05230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU62_RS05230	COG1263	PTS System
ISU62_RS05255	COG0735	belongs to the Fur family
ISU62_RS05270	COG0596	Alpha beta hydrolase
ISU62_RS05280	COG0582	viral genome integration into host DNA
ISU62_RS05315	COG2113	Glycine betaine
ISU62_RS05320	COG4176	ABC-type proline glycine betaine transport system permease component
ISU62_RS05325	COG4175	Glycine betaine
ISU62_RS05330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ISU62_RS05370	COG1278	Cold shock
ISU62_RS05375	COG0747	negative chemotaxis
ISU62_RS05385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU62_RS05390	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ISU62_RS05395	COG1124	(ABC) transporter
ISU62_RS05400	COG0831	urea catabolic process
ISU62_RS05425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ISU62_RS05435	COG4413	Urea transporter
ISU62_RS05440	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU62_RS05450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU62_RS05460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU62_RS05470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU62_RS05475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU62_RS05480	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISU62_RS05485	COG1917	Cupin 2, conserved barrel domain protein
ISU62_RS05485	COG2169	Transcriptional regulator
ISU62_RS05500	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ISU62_RS05505	COG0033	Phosphoglucomutase
ISU62_RS05520	COG0745	RESPONSE REGULATOR receiver
ISU62_RS05525	COG2205	protein histidine kinase activity
ISU62_RS05560	COG3272	Protein of unknown function (DUF1722)
ISU62_RS05570	COG5212	phosphodiesterase
ISU62_RS05575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ISU62_RS05590	COG1984	allophanate hydrolase subunit 2
ISU62_RS05635	COG0513	Belongs to the DEAD box helicase family
ISU62_RS05645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ISU62_RS05660	COG3026	antisigma factor binding
ISU62_RS05665	COG3086	response to oxidative stress
ISU62_RS05700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ISU62_RS05715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU62_RS05720	COG1737	Transcriptional regulator
ISU62_RS05730	COG0560	Phosphoserine phosphatase
ISU62_RS05775	COG2205	protein histidine kinase activity
ISU62_RS05780	COG3170	Tfp pilus assembly protein FimV
ISU62_RS05785	COG2204	response regulator
ISU62_RS05790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ISU62_RS05790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU62_RS05795	COG0347	Belongs to the P(II) protein family
ISU62_RS05805	COG1017	nitric oxide dioxygenase activity
ISU62_RS05805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU62_RS05820	COG2814	Major facilitator Superfamily
ISU62_RS05825	COG3711	transcriptional antiterminator
ISU62_RS05830	COG3683	transport system, periplasmic component
ISU62_RS05835	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU62_RS05855	COG1104	cysteine desulfurase activity
ISU62_RS05860	COG0822	iron-sulfur transferase activity
ISU62_RS05875	COG0443	Heat shock 70 kDa protein
ISU62_RS05880	COG0633	Ferredoxin
ISU62_RS05885	COG2975	iron-sulfur cluster assembly
ISU62_RS05910	COG3468	outer membrane autotransporter barrel domain protein
ISU62_RS05915	COG3468	outer membrane autotransporter barrel domain protein
ISU62_RS05955	COG2976	Protein conserved in bacteria
ISU62_RS05960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU62_RS05975	COG1645	bacterial-type flagellum-dependent swarming motility
ISU62_RS05985	COG0516	GMP reductase activity
ISU62_RS05985	COG0517	IMP dehydrogenase activity
ISU62_RS06030	COG3328	transposase activity
ISU62_RS06045	COG0351	phosphomethylpyrimidine kinase
ISU62_RS06070	COG0826	peptidase U32
ISU62_RS06075	COG3422	double-strand break repair
ISU62_RS06080	COG0745	RESPONSE REGULATOR receiver
ISU62_RS06110	COG3842	ATPase activity
ISU62_RS06120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISU62_RS06130	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU62_RS06135	COG1177	transmembrane transport
ISU62_RS06145	COG2239	Acts as a magnesium transporter
ISU62_RS06160	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ISU62_RS06170	COG0581	inorganic phosphate transmembrane transporter activity
ISU62_RS06185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU62_RS06190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ISU62_RS06215	COG1393	Belongs to the ArsC family
ISU62_RS06220	COG4783	chaperone-mediated protein folding
ISU62_RS06225	COG0628	permease
ISU62_RS06235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ISU62_RS06240	COG2716	regulation of RNA biosynthetic process
ISU62_RS06250	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ISU62_RS06265	COG2321	neutral zinc metallopeptidase
ISU62_RS06285	COG1876	peptidase activity
ISU62_RS06295	COG1393	Belongs to the ArsC family
ISU62_RS06310	COG1175	transmembrane transport
ISU62_RS06315	COG3842	ATPase activity
ISU62_RS06325	COG3119	arylsulfatase activity
ISU62_RS06330	COG0641	radical SAM
ISU62_RS06335	COG1988	membrane-bound metal-dependent
ISU62_RS06345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU62_RS06355	COG2197	response regulator
ISU62_RS06360	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU62_RS06360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU62_RS06365	COG3062	negative regulation of establishment of protein localization
ISU62_RS06375	COG3043	anaerobic respiration
ISU62_RS06380	COG3005	denitrification pathway
ISU62_RS06420	COG3111	PFAM Bacterial OB fold (BOF) protein
ISU62_RS06430	COG2837	iron assimilation
ISU62_RS06435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISU62_RS06445	COG4886	Leucine-rich repeat (LRR) protein
ISU62_RS06455	COG2731	YhcH YjgK YiaL family protein
ISU62_RS06460	COG1737	Transcriptional regulator
ISU62_RS06470	COG4150	thiosulfate binding
ISU62_RS06475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ISU62_RS06480	COG4208	sulfate ABC transporter
ISU62_RS06500	COG0745	RESPONSE REGULATOR receiver
ISU62_RS06505	COG5002	protein histidine kinase activity
ISU62_RS06505	COG3850	Histidine kinase
ISU62_RS06515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ISU62_RS06535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ISU62_RS06550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU62_RS06555	COG0745	RESPONSE REGULATOR receiver
ISU62_RS06560	COG2205	protein histidine kinase activity
ISU62_RS06580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU62_RS06590	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ISU62_RS06605	COG3530	Putative quorum-sensing-regulated virulence factor
ISU62_RS06670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU62_RS06685	COG0667	Aldo Keto reductase
ISU62_RS06710	COG0436	Aminotransferase
ISU62_RS06715	COG3038	cytochrome b561
ISU62_RS06745	COG3381	protein complex oligomerization
ISU62_RS06750	COG3302	dmso reductase anchor subunit
ISU62_RS06755	COG0437	4 iron, 4 sulfur cluster binding
ISU62_RS06760	COG0243	molybdopterin cofactor binding
ISU62_RS06795	COG2951	lytic endotransglycosylase activity
ISU62_RS06855	COG3121	Chaperone
ISU62_RS06860	COG3188	usher protein
ISU62_RS06865	COG3328	transposase activity
ISU62_RS06870	COG3188	usher protein
ISU62_RS06960	COG2824	Alkylphosphonate utilization operon protein PhnA
ISU62_RS06970	COG1704	LemA family
ISU62_RS06990	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU62_RS06995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU62_RS07000	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU62_RS07010	COG1138	Cytochrome C-type biogenesis protein
ISU62_RS07015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ISU62_RS07020	COG4235	cytochrome complex assembly
ISU62_RS07020	COG3088	subunit of a heme lyase
ISU62_RS07025	COG4235	cytochrome complex assembly
ISU62_RS07025	COG3088	subunit of a heme lyase
ISU62_RS07040	COG3691	Protein conserved in bacteria
ISU62_RS07055	COG2062	phosphohistidine phosphatase, SixA
ISU62_RS07070	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU62_RS07085	COG0730	response to heat
ISU62_RS07090	COG3101	peptidyl-lysine hydroxylation
ISU62_RS07105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU62_RS07125	COG0697	spore germination
ISU62_RS07140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU62_RS07150	COG0586	Pfam SNARE associated Golgi protein
ISU62_RS07160	COG0285	dihydrofolate synthase activity
ISU62_RS07165	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ISU62_RS07170	COG1286	toxin biosynthetic process
ISU62_RS07175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ISU62_RS07185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU62_RS07190	COG4215	(ABC) transporter
ISU62_RS07195	COG4160	amino acid transport
ISU62_RS07200	COG4598	ABC transporter
ISU62_RS07205	COG1090	epimerase
ISU62_RS07215	COG0622	Phosphoesterase
ISU62_RS07220	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ISU62_RS07235	COG3328	transposase activity
ISU62_RS07250	COG1609	Transcriptional regulator
ISU62_RS07255	COG0280	phosphate acetyltransferase
ISU62_RS07255	COG0857	belongs to the CobB CobQ family
ISU62_RS07275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU62_RS07280	COG0490	domain, Protein
ISU62_RS07280	COG0471	metal ion transport
ISU62_RS07290	COG0436	Aminotransferase
ISU62_RS07295	COG0583	DNA-binding transcription factor activity
ISU62_RS07305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU62_RS07325	COG1034	ATP synthesis coupled electron transport
ISU62_RS07340	COG0839	Belongs to the complex I subunit 6 family
ISU62_RS07350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ISU62_RS07355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU62_RS07370	COG2731	YhcH YjgK YiaL family protein
ISU62_RS07375	COG3265	gluconokinase activity
ISU62_RS07380	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS07385	COG1649	PFAM Uncharacterised BCR, COG1649
ISU62_RS07390	COG1609	Transcriptional regulator
ISU62_RS07395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU62_RS07410	COG0129	dihydroxy-acid dehydratase activity
ISU62_RS07415	COG4575	ribosome binding
ISU62_RS07425	COG1169	isochorismate synthase
ISU62_RS07440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ISU62_RS07455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ISU62_RS07490	COG1126	abc transporter atp-binding protein
ISU62_RS07495	COG0765	amino acid transport
ISU62_RS07500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU62_RS07530	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ISU62_RS07550	COG1063	alcohol dehydrogenase
ISU62_RS07555	COG1879	ABC-type sugar transport system periplasmic component
ISU62_RS07560	COG1129	ABC transporter
ISU62_RS07565	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS07570	COG1609	Transcriptional regulator
ISU62_RS07575	COG0583	DNA-binding transcription factor activity
ISU62_RS07580	COG0473	3-isopropylmalate dehydrogenase activity
ISU62_RS07590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU62_RS07595	COG4638	Rieske (2fe-2S)
ISU62_RS07600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU62_RS07605	COG2831	hemolysin activation secretion protein
ISU62_RS07610	COG3210	domain, Protein
ISU62_RS07650	COG3210	domain, Protein
ISU62_RS07660	COG3842	ATPase activity
ISU62_RS07670	COG1609	Transcriptional regulator
ISU62_RS07685	COG0395	ABC-type sugar transport system, permease component
ISU62_RS07690	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ISU62_RS07710	COG0668	transmembrane transport
ISU62_RS07715	COG1518	maintenance of DNA repeat elements
ISU62_RS07720	COG1203	CRISPR-associated helicase, Cas3
ISU62_RS07745	COG0667	Aldo Keto reductase
ISU62_RS07755	COG0477	Major facilitator Superfamily
ISU62_RS07765	COG0583	DNA-binding transcription factor activity
ISU62_RS07770	COG2771	luxR family
ISU62_RS07775	COG3916	Acyl-homoserine-lactone synthase
ISU62_RS07795	COG0628	permease
ISU62_RS07815	COG3328	transposase activity
ISU62_RS07835	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ISU62_RS07845	COG3328	transposase activity
ISU62_RS07855	COG0564	pseudouridine synthase activity
ISU62_RS07860	COG0424	maF-like protein
ISU62_RS07865	COG1399	metal-binding, possibly nucleic acid-binding protein
ISU62_RS07870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ISU62_RS07900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU62_RS07910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU62_RS07915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ISU62_RS07925	COG0470	DNA polymerase III
ISU62_RS07930	COG0084	hydrolase, TatD family'
ISU62_RS07935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU62_RS07935	COG1263	PTS System
ISU62_RS07945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISU62_RS07950	COG0537	adenosine 5'-monophosphoramidase activity
ISU62_RS07955	COG5633	Lipoprotein
ISU62_RS07970	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU62_RS07980	COG1252	NADH dehydrogenase
ISU62_RS07995	COG3328	transposase activity
ISU62_RS08000	COG3134	Outer membrane lipoprotein
ISU62_RS08005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ISU62_RS08010	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU62_RS08020	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU62_RS08025	COG1940	carbohydrate kinase activity
ISU62_RS08045	COG2850	peptidyl-arginine hydroxylation
ISU62_RS08055	COG0745	RESPONSE REGULATOR receiver
ISU62_RS08065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ISU62_RS08085	COG1187	pseudouridine synthase activity
ISU62_RS08090	COG0538	isocitrate dehydrogenase activity
ISU62_RS08105	COG0840	transmembrane signaling receptor activity
ISU62_RS08110	COG0702	epimerase
ISU62_RS08115	COG1733	regulation of RNA biosynthetic process
ISU62_RS08140	COG1522	sequence-specific DNA binding
ISU62_RS08150	COG3321	synthase
ISU62_RS08150	COG0604	alcohol dehydrogenase
ISU62_RS08150	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS08175	COG1285	pathogenesis
ISU62_RS08200	COG1360	Flagellar Motor Protein
ISU62_RS08205	COG2198	Histidine kinase
ISU62_RS08205	COG0643	Histidine kinase
ISU62_RS08210	COG0835	chemotaxis
ISU62_RS08215	COG2271	Major facilitator Superfamily
ISU62_RS08220	COG0251	oxidation-reduction process
ISU62_RS08230	COG2964	Protein conserved in bacteria
ISU62_RS08250	COG0840	transmembrane signaling receptor activity
ISU62_RS08255	COG0840	transmembrane signaling receptor activity
ISU62_RS08260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ISU62_RS08270	COG0745	RESPONSE REGULATOR receiver
ISU62_RS08275	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ISU62_RS08280	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU62_RS08285	COG5295	Hep Hag repeat protein
ISU62_RS08295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ISU62_RS08335	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU62_RS08340	COG1177	transmembrane transport
ISU62_RS08355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU62_RS08380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU62_RS08385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU62_RS08390	COG1120	ATPase activity
ISU62_RS08410	COG4160	amino acid transport
ISU62_RS08415	COG4215	(ABC) transporter
ISU62_RS08420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU62_RS08425	COG1126	abc transporter atp-binding protein
ISU62_RS08430	COG1605	Chorismate mutase
ISU62_RS08440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU62_RS08445	COG0702	epimerase
ISU62_RS08450	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ISU62_RS08460	COG0028	Belongs to the TPP enzyme family
ISU62_RS08465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU62_RS08475	COG2431	L-lysine efflux transmembrane transporter activity
ISU62_RS08480	COG3593	DNA synthesis involved in DNA repair
ISU62_RS08485	COG2990	Protein conserved in bacteria
ISU62_RS08490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU62_RS08500	COG1278	Cold shock
ISU62_RS08510	COG0542	response to heat
ISU62_RS08520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ISU62_RS08530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ISU62_RS08540	COG0492	ferredoxin-NADP+ reductase activity
ISU62_RS08550	COG3107	peptidoglycan biosynthetic process
ISU62_RS08550	COG1674	ftsk spoiiie
ISU62_RS08560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ISU62_RS08575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISU62_RS08585	COG1882	Formate acetyltransferase
ISU62_RS08590	COG2116	formate transmembrane transporter activity
ISU62_RS08595	COG1944	ATP diphosphatase activity
ISU62_RS08600	COG0252	asparaginase activity
ISU62_RS08605	COG5295	Hep Hag repeat protein
ISU62_RS08605	COG5295	Hep Hag repeat protein
ISU62_RS08630	COG0539	negative regulation of cytoplasmic translation
ISU62_RS08640	COG0658	competence protein
ISU62_RS08640	COG2333	competence protein COMEC
ISU62_RS08655	COG5383	Protein conserved in bacteria
ISU62_RS08660	COG1278	Cold shock
ISU62_RS08675	COG3173	Aminoglycoside phosphotransferase
ISU62_RS08680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ISU62_RS08705	COG2989	Protein conserved in bacteria
ISU62_RS08710	COG3108	Peptidase M15
ISU62_RS08715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU62_RS08725	COG1448	Aminotransferase
ISU62_RS08745	COG0308	aminopeptidase N
ISU62_RS08760	COG0633	Ferredoxin
ISU62_RS08760	COG3217	Mosc domain protein beta barrel domain protein
ISU62_RS08770	COG0488	(ABC) transporter
ISU62_RS08775	COG2995	paraquat-inducible protein a
ISU62_RS08780	COG3008	intermembrane lipid transfer
ISU62_RS08780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU62_RS08790	COG3009	Protein conserved in bacteria
ISU62_RS08795	COG3130	regulation of translation
ISU62_RS08835	COG1067	ATP-dependent peptidase activity
ISU62_RS08860	COG3070	regulator of competence-specific genes
ISU62_RS08865	COG1289	transmembrane transporter activity
ISU62_RS08870	COG3304	Inner membrane component domain
ISU62_RS08875	COG0210	DNA helicase
ISU62_RS08890	COG1832	CoA-binding protein
ISU62_RS08910	COG2920	part of a sulfur-relay system
ISU62_RS08935	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS08945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ISU62_RS08950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU62_RS08955	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS08960	COG3425	synthase
ISU62_RS08970	COG1024	Enoyl-CoA hydratase
ISU62_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS08985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ISU62_RS08990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ISU62_RS09120	COG0488	(ABC) transporter
ISU62_RS09130	COG3328	transposase activity
ISU62_RS09140	COG0303	'Molybdopterin
ISU62_RS09150	COG1136	(ABC) transporter
ISU62_RS09180	COG0583	DNA-binding transcription factor activity
ISU62_RS09185	COG0477	Major facilitator Superfamily
ISU62_RS09195	COG2311	Membrane
ISU62_RS09210	COG4211	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS09215	COG2949	membrane
ISU62_RS09230	COG1346	cytolysis
ISU62_RS09240	COG2814	Major facilitator Superfamily
ISU62_RS09270	COG0489	protein tyrosine kinase activity
ISU62_RS09285	COG2982	Protein involved in outer membrane biogenesis
ISU62_RS09290	COG1253	flavin adenine dinucleotide binding
ISU62_RS09295	COG4114	ferric iron reductase
ISU62_RS09300	COG0076	glutamate decarboxylase activity
ISU62_RS09305	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ISU62_RS09320	COG1120	ATPase activity
ISU62_RS09325	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU62_RS09330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU62_RS09335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU62_RS09350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU62_RS09355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU62_RS09365	COG0140	phosphoribosyl-ATP diphosphatase activity
ISU62_RS09365	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ISU62_RS09385	COG0131	Imidazoleglycerol-phosphate dehydratase
ISU62_RS09385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU62_RS09395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ISU62_RS09410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU62_RS09425	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS09430	COG1129	ABC transporter
ISU62_RS09435	COG1129	ABC transporter
ISU62_RS09440	COG0371	Dehydrogenase
ISU62_RS09445	COG0531	amino acid
ISU62_RS09455	COG2925	Exonuclease
ISU62_RS09470	COG3328	transposase activity
ISU62_RS09475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU62_RS09485	COG3001	Fructosamine kinase
ISU62_RS09495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU62_RS09500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU62_RS09505	COG1121	(ABC) transporter
ISU62_RS09510	COG0803	Belongs to the bacterial solute-binding protein 9 family
ISU62_RS09530	COG4249	Peptidase C14 caspase catalytic subunit p20
ISU62_RS09565	COG0072	phenylalanine-tRNA ligase activity
ISU62_RS09565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ISU62_RS09570	COG0776	regulation of translation
ISU62_RS09585	COG0386	Belongs to the glutathione peroxidase family
ISU62_RS09635	COG0791	NLP P60 protein
ISU62_RS09660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU62_RS09660	COG0574	Belongs to the PEP-utilizing enzyme family
ISU62_RS09670	COG0628	permease
ISU62_RS09675	COG0277	FAD linked oxidase domain protein
ISU62_RS09675	COG0247	lactate metabolic process
ISU62_RS09680	COG2050	protein possibly involved in aromatic compounds catabolism
ISU62_RS09685	COG0316	Belongs to the HesB IscA family
ISU62_RS09690	COG0719	Fe-S assembly protein
ISU62_RS09695	COG0396	ATPase activity
ISU62_RS09700	COG0719	Fe-S assembly protein
ISU62_RS09715	COG1388	LysM domain
ISU62_RS09715	COG1376	ErfK ybiS ycfS ynhG family protein
ISU62_RS09765	COG0307	riboflavin synthase, alpha
ISU62_RS09770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ISU62_RS09775	COG2814	Major facilitator Superfamily
ISU62_RS09780	COG0583	DNA-binding transcription factor activity
ISU62_RS09800	COG0791	NLP P60 protein
ISU62_RS09805	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ISU62_RS09815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISU62_RS09820	COG0346	lactoylglutathione lyase activity
ISU62_RS09830	COG1902	pentaerythritol trinitrate reductase activity
ISU62_RS09835	COG1309	transcriptional regulator
ISU62_RS09840	COG2194	sulfuric ester hydrolase activity
ISU62_RS09845	COG3313	Fe-S protein
ISU62_RS09850	COG4989	oxidoreductase activity
ISU62_RS09865	COG3133	Outer membrane lipoprotein
ISU62_RS09875	COG3895	Periplasmic Protein
ISU62_RS09895	COG0625	glutathione transferase activity
ISU62_RS09910	COG3104	oligopeptide transport
ISU62_RS09915	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU62_RS09915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU62_RS09920	COG4172	Belongs to the ABC transporter superfamily
ISU62_RS09930	COG4171	peptide transport system, permease
ISU62_RS09935	COG4168	peptide transport system, permease
ISU62_RS09940	COG4166	transmembrane transport
ISU62_RS09950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISU62_RS09955	COG1842	Phage shock protein A
ISU62_RS09965	COG1983	PspC domain protein
ISU62_RS09975	COG3106	COG3106 Predicted ATPase
ISU62_RS09985	COG5654	RES domain protein
ISU62_RS09990	COG5642	Protein of unknown function (DUF2384)
ISU62_RS10005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ISU62_RS10010	COG4948	Mandelate Racemase Muconate Lactonizing
ISU62_RS10015	COG2866	Carboxypeptidase
ISU62_RS10020	COG4166	transmembrane transport
ISU62_RS10035	COG0657	acetylesterase activity
ISU62_RS10045	COG1013	pyruvate-flavodoxin oxidoreductase activity
ISU62_RS10045	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ISU62_RS10045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU62_RS10045	COG0674	pyruvate-flavodoxin oxidoreductase activity
ISU62_RS10055	COG1285	pathogenesis
ISU62_RS10060	COG3042	response to heat
ISU62_RS10065	COG3187	Heat shock protein
ISU62_RS10070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU62_RS10075	COG2911	Protein conserved in bacteria
ISU62_RS10085	COG3784	Protein of unknown function (DUF1318)
ISU62_RS10090	COG0246	Mannitol dehydrogenase
ISU62_RS10095	COG2390	Transcriptional regulator
ISU62_RS10105	COG1643	Atp-dependent helicase
ISU62_RS10120	COG3591	Belongs to the peptidase S1B family
ISU62_RS10130	COG3038	cytochrome b561
ISU62_RS10155	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ISU62_RS10160	COG2205	protein histidine kinase activity
ISU62_RS10165	COG0745	RESPONSE REGULATOR receiver
ISU62_RS10175	COG0531	amino acid
ISU62_RS10185	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ISU62_RS10190	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ISU62_RS10195	COG0589	response to stress
ISU62_RS10200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISU62_RS10205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU62_RS10225	COG1011	Hydrolase
ISU62_RS10230	COG0440	acetolactate synthase activity
ISU62_RS10235	COG0028	Belongs to the TPP enzyme family
ISU62_RS10265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ISU62_RS10275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU62_RS10295	COG1609	Transcriptional regulator
ISU62_RS10300	COG0038	chloride channel
ISU62_RS10305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ISU62_RS10310	COG1940	carbohydrate kinase activity
ISU62_RS10315	COG0583	DNA-binding transcription factor activity
ISU62_RS10330	COG0114	fumarate hydratase activity
ISU62_RS10340	COG5339	Protein conserved in bacteria
ISU62_RS10350	COG0385	Bile acid
ISU62_RS10355	COG0673	inositol 2-dehydrogenase activity
ISU62_RS10365	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS10370	COG1129	ABC transporter
ISU62_RS10375	COG1879	ABC-type sugar transport system periplasmic component
ISU62_RS10390	COG2274	protein secretion by the type I secretion system
ISU62_RS10395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU62_RS10405	COG1132	(ABC) transporter
ISU62_RS10435	COG3708	Transcriptional regulator
ISU62_RS10435	COG2207	Transcriptional regulator
ISU62_RS10440	COG4658	electron transport chain
ISU62_RS10445	COG4659	FMN binding
ISU62_RS10455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ISU62_RS10460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU62_RS10465	COG2271	Major facilitator Superfamily
ISU62_RS10475	COG1966	Carbon starvation protein
ISU62_RS10480	COG2879	small protein
ISU62_RS10485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISU62_RS10505	COG0023	Translation Initiation Factor
ISU62_RS10520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ISU62_RS10525	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ISU62_RS10530	COG0671	phosphoesterase, PA-phosphatase related
ISU62_RS10540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ISU62_RS10550	COG0583	DNA-binding transcription factor activity
ISU62_RS10570	COG0616	signal peptide processing
ISU62_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS10585	COG1187	pseudouridine synthase activity
ISU62_RS10590	COG0009	L-threonylcarbamoyladenylate synthase
ISU62_RS10610	COG0512	Glutamine amidotransferase of anthranilate synthase
ISU62_RS10620	COG0135	phosphoribosylanthranilate isomerase activity
ISU62_RS10620	COG0134	indole-3-glycerol-phosphate synthase activity
ISU62_RS10640	COG3047	cAMP biosynthetic process
ISU62_RS10675	COG3328	transposase activity
ISU62_RS10680	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ISU62_RS10685	COG2350	Protein conserved in bacteria
ISU62_RS10730	COG4608	Belongs to the ABC transporter superfamily
ISU62_RS10735	COG0444	Belongs to the ABC transporter superfamily
ISU62_RS10740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU62_RS10745	COG0601	transmembrane transport
ISU62_RS10755	COG2095	MarC family integral membrane protein
ISU62_RS10760	COG1012	belongs to the aldehyde dehydrogenase family
ISU62_RS10760	COG1454	alcohol dehydrogenase
ISU62_RS10790	COG0745	RESPONSE REGULATOR receiver
ISU62_RS10800	COG0788	formyltetrahydrofolate deformylase activity
ISU62_RS10805	COG3328	transposase activity
ISU62_RS10825	COG3328	transposase activity
ISU62_RS10830	COG0583	DNA-binding transcription factor activity
ISU62_RS10835	COG0708	Exodeoxyribonuclease III
ISU62_RS10840	COG0494	nUDIX hydrolase
ISU62_RS10850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ISU62_RS10860	COG0778	Nitroreductase
ISU62_RS10865	COG0616	signal peptide processing
ISU62_RS10870	COG0252	asparaginase activity
ISU62_RS10875	COG1335	isochorismatase
ISU62_RS10880	COG3139	Protein of unknown function (DUF1315)
ISU62_RS10900	COG3713	MltA-interacting MipA family protein
ISU62_RS10905	COG2766	serine protein kinase
ISU62_RS10920	COG0583	DNA-binding transcription factor activity
ISU62_RS10930	COG2814	Major facilitator Superfamily
ISU62_RS10940	COG2719	SpoVR family
ISU62_RS10970	COG1104	cysteine desulfurase activity
ISU62_RS10980	COG3328	transposase activity
ISU62_RS11140	COG3328	transposase activity
ISU62_RS11240	COG0582	viral genome integration into host DNA
ISU62_RS11250	COG0179	Fumarylacetoacetate (FAA) hydrolase
ISU62_RS11255	COG2951	lytic endotransglycosylase activity
ISU62_RS11270	COG2894	cell division
ISU62_RS11275	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ISU62_RS11285	COG0318	PFAM AMP-dependent synthetase and ligase
ISU62_RS11295	COG3065	identical protein binding
ISU62_RS11305	COG1199	ATP-dependent helicase activity
ISU62_RS11310	COG0251	oxidation-reduction process
ISU62_RS11325	COG0800	Aldolase
ISU62_RS11330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ISU62_RS11335	COG1737	Transcriptional regulator
ISU62_RS11340	COG0469	pyruvate kinase activity
ISU62_RS11350	COG1560	Kdo2-lipid A biosynthetic process
ISU62_RS11355	COG0739	heme binding
ISU62_RS11360	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ISU62_RS11370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU62_RS11395	COG0494	nUDIX hydrolase
ISU62_RS11405	COG1801	Protein of unknown function DUF72
ISU62_RS11410	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ISU62_RS11430	COG3102	Protein conserved in bacteria
ISU62_RS11450	COG0728	peptidoglycan biosynthetic process
ISU62_RS11460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU62_RS11475	COG3381	protein complex oligomerization
ISU62_RS11490	COG1940	carbohydrate kinase activity
ISU62_RS11495	COG0584	glycerophosphoryl diester phosphodiesterase
ISU62_RS11520	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU62_RS11525	COG3833	ABC-type maltose transport systems, permease component
ISU62_RS11545	COG0659	secondary active sulfate transmembrane transporter activity
ISU62_RS11565	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU62_RS11590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ISU62_RS11605	COG0012	GTP binding
ISU62_RS11655	COG5002	protein histidine kinase activity
ISU62_RS11700	COG0500	methyltransferase
ISU62_RS11720	COG3328	transposase activity
ISU62_RS11765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU62_RS11770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU62_RS11775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU62_RS11790	COG0402	S-adenosylhomocysteine deaminase activity
ISU62_RS11855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU62_RS11865	COG3850	Histidine kinase
ISU62_RS11870	COG0387	Pfam Sodium calcium exchanger
ISU62_RS11875	COG1702	phosphate starvation-inducible protein PhoH
ISU62_RS11890	COG3658	cytochrome
ISU62_RS11895	COG1215	transferase activity, transferring glycosyl groups
ISU62_RS11900	COG0726	polysaccharide deacetylase
ISU62_RS11900	COG1649	PFAM Uncharacterised BCR, COG1649
ISU62_RS11905	COG0457	Tetratricopeptide repeat
ISU62_RS11910	COG0006	proline dipeptidase activity
ISU62_RS11930	COG0577	efflux transmembrane transporter activity
ISU62_RS11930	COG1136	(ABC) transporter
ISU62_RS11940	COG0577	efflux transmembrane transporter activity
ISU62_RS11940	COG1136	(ABC) transporter
ISU62_RS11955	COG0672	)-iron permease
ISU62_RS11970	COG2066	Belongs to the glutaminase family
ISU62_RS11980	COG1349	DNA-binding transcription factor activity
ISU62_RS11990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU62_RS11995	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU62_RS12010	COG2814	Major facilitator Superfamily
ISU62_RS12035	COG2030	dehydratase
ISU62_RS12040	COG0427	acetyl-CoA hydrolase
ISU62_RS12050	COG2205	protein histidine kinase activity
ISU62_RS12050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU62_RS12065	COG3188	usher protein
ISU62_RS12075	COG3121	Chaperone
ISU62_RS12085	COG0582	viral genome integration into host DNA
ISU62_RS12090	COG1169	isochorismate synthase
ISU62_RS12095	COG2814	Major facilitator Superfamily
ISU62_RS12100	COG1132	(ABC) transporter
ISU62_RS12115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU62_RS12115	COG2226	methyltransferase
ISU62_RS12115	COG3433	isochorismatase activity
ISU62_RS12135	COG1021	2,3-dihydroxybenzoate-AMP ligase
ISU62_RS12140	COG4771	TonB-dependent receptor
ISU62_RS12200	COG3842	ATPase activity
ISU62_RS12205	COG0395	ABC-type sugar transport system, permease component
ISU62_RS12210	COG1175	transmembrane transport
ISU62_RS12220	COG0673	inositol 2-dehydrogenase activity
ISU62_RS12225	COG2188	Transcriptional regulator
ISU62_RS12360	COG3136	membrane protein required for alginate biosynthesis
ISU62_RS12380	COG1113	amino acid transport
ISU62_RS12400	COG2822	iron ion transport
ISU62_RS12405	COG0672	)-iron permease
ISU62_RS12420	COG0506	proline dehydrogenase activity
ISU62_RS12420	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU62_RS12420	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU62_RS12435	COG1126	abc transporter atp-binding protein
ISU62_RS12440	COG0765	amino acid transport
ISU62_RS12445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU62_RS12460	COG1191	sigma factor activity
ISU62_RS12490	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ISU62_RS12495	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ISU62_RS12500	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ISU62_RS12520	COG1677	Flagellar hook-basal body complex protein FliE
ISU62_RS12540	COG1157	protein secretion by the type III secretion system
ISU62_RS12555	COG1580	Controls the rotational direction of flagella during chemotaxis
ISU62_RS12580	COG1987	bacterial-type flagellum assembly
ISU62_RS12600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU62_RS12605	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS12610	COG1129	ABC transporter
ISU62_RS12620	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS12625	COG3347	Dehydrogenase
ISU62_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS12630	COG2390	Transcriptional regulator
ISU62_RS12640	COG1256	bacterial-type flagellum assembly
ISU62_RS12680	COG1558	bacterial-type flagellum-dependent cell motility
ISU62_RS12685	COG1815	bacterial-type flagellum-dependent cell motility
ISU62_RS12695	COG2747	anti-sigma28 factor FlgM
ISU62_RS12700	COG3418	PFAM FlgN family protein
ISU62_RS12725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU62_RS12730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU62_RS12755	COG2372	response to copper ion
ISU62_RS12760	COG1528	Iron-storage protein
ISU62_RS12775	COG1770	oligopeptidase
ISU62_RS12790	COG3141	response to X-ray
ISU62_RS12795	COG0513	Belongs to the DEAD box helicase family
ISU62_RS12820	COG1760	l-serine dehydratase
ISU62_RS12825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISU62_RS12830	COG2368	4-hydroxyphenylacetate
ISU62_RS12845	COG3971	2-oxopent-4-enoate hydratase activity
ISU62_RS12855	COG3384	dioxygenase
ISU62_RS12860	COG1012	belongs to the aldehyde dehydrogenase family
ISU62_RS12875	COG1846	Transcriptional regulator
ISU62_RS12885	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU62_RS12885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU62_RS12890	COG3715	PTS system
ISU62_RS12895	COG3716	PTS system mannose fructose sorbose family IID component
ISU62_RS12915	COG5001	Diguanylate cyclase
ISU62_RS12915	COG5002	protein histidine kinase activity
ISU62_RS12915	COG3447	MASE1 domain protein
ISU62_RS12925	COG2226	methyltransferase
ISU62_RS12930	COG1496	oxidoreductase activity
ISU62_RS12950	COG1113	amino acid transport
ISU62_RS12985	COG2207	Transcriptional regulator
ISU62_RS12995	COG1132	(ABC) transporter
ISU62_RS13040	COG3328	transposase activity
ISU62_RS13045	COG2223	nitrite transmembrane transporter activity
ISU62_RS13065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ISU62_RS13090	COG3122	Protein conserved in bacteria
ISU62_RS13110	COG0534	Mate efflux family protein
ISU62_RS13125	COG4948	Mandelate Racemase Muconate Lactonizing
ISU62_RS13135	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS13140	COG3011	Protein conserved in bacteria
ISU62_RS13145	COG2271	Major facilitator Superfamily
ISU62_RS13155	COG1388	LysM domain
ISU62_RS13155	COG1470	cell adhesion involved in biofilm formation
ISU62_RS13160	COG3328	transposase activity
ISU62_RS13165	COG1917	Cupin 2, conserved barrel domain protein
ISU62_RS13175	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS13185	COG1175	transmembrane transport
ISU62_RS13190	COG0395	ABC-type sugar transport system, permease component
ISU62_RS13195	COG3842	ATPase activity
ISU62_RS13200	COG1653	transport
ISU62_RS13205	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU62_RS13210	COG1988	membrane-bound metal-dependent
ISU62_RS13215	COG1823	symporter activity
ISU62_RS13220	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU62_RS13230	COG0823	Involved in the tonB-independent uptake of proteins
ISU62_RS13235	COG2814	Major facilitator Superfamily
ISU62_RS13240	COG3121	Chaperone
ISU62_RS13255	COG3121	Chaperone
ISU62_RS13260	COG3539	Fimbrial protein
ISU62_RS13270	COG0793	Belongs to the peptidase S41A family
ISU62_RS13280	COG1956	GAF domain-containing protein
ISU62_RS13285	COG2995	paraquat-inducible protein a
ISU62_RS13290	COG3008	intermembrane lipid transfer
ISU62_RS13310	COG3121	Chaperone
ISU62_RS13350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ISU62_RS13380	COG0671	phosphoesterase, PA-phosphatase related
ISU62_RS13390	COG1349	DNA-binding transcription factor activity
ISU62_RS13395	COG0814	amino acid
ISU62_RS13400	COG1686	Belongs to the peptidase S11 family
ISU62_RS13405	COG2011	ABC-type metal ion transport system permease component
ISU62_RS13430	COG0625	glutathione transferase activity
ISU62_RS13435	COG4771	TonB-dependent receptor
ISU62_RS13445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU62_RS13455	COG0833	amino acid
ISU62_RS13460	COG0583	DNA-binding transcription factor activity
ISU62_RS13465	COG2855	membrane
ISU62_RS13475	COG3188	usher protein
ISU62_RS13480	COG3121	Chaperone
ISU62_RS13495	COG3710	Transcriptional regulator
ISU62_RS13500	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ISU62_RS13500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU62_RS13500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU62_RS13505	COG1105	Belongs to the carbohydrate kinase PfkB family
ISU62_RS13515	COG0494	nUDIX hydrolase
ISU62_RS13525	COG1129	ABC transporter
ISU62_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS13590	COG0246	Mannitol dehydrogenase
ISU62_RS13595	COG2186	Transcriptional regulator
ISU62_RS13600	COG0523	cobalamin synthesis protein
ISU62_RS13605	COG0671	phosphoesterase, PA-phosphatase related
ISU62_RS13610	COG0791	NLP P60 protein
ISU62_RS13615	COG2200	EAL domain
ISU62_RS13620	COG4166	transmembrane transport
ISU62_RS13625	COG4174	ABC transporter (Permease)
ISU62_RS13630	COG4239	(ABC) transporter, permease
ISU62_RS13635	COG4172	Belongs to the ABC transporter superfamily
ISU62_RS13645	COG2814	Major facilitator Superfamily
ISU62_RS13650	COG1187	pseudouridine synthase activity
ISU62_RS13655	COG1061	Type III restriction enzyme res subunit
ISU62_RS13675	COG3082	Protein of unknown function (DUF1414)
ISU62_RS13680	COG3083	sulfuric ester hydrolase activity
ISU62_RS13695	COG3157	Type VI secretion system effector, Hcp
ISU62_RS13715	COG2723	6-phospho-beta-galactosidase activity
ISU62_RS13720	COG1737	Transcriptional regulator
ISU62_RS13740	COG3299	homolog of phage Mu protein gp47
ISU62_RS13780	COG4386	tail sheath protein
ISU62_RS13800	COG3622	Belongs to the hyi family
ISU62_RS13805	COG1349	DNA-binding transcription factor activity
ISU62_RS13815	COG3395	kinase activity
ISU62_RS13855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ISU62_RS13880	COG2223	nitrite transmembrane transporter activity
ISU62_RS13885	COG2198	Histidine kinase
ISU62_RS13885	COG0642	Histidine kinase
ISU62_RS13890	COG0642	Histidine kinase
ISU62_RS13890	COG2198	Histidine kinase
ISU62_RS13900	COG2205	protein histidine kinase activity
ISU62_RS13900	COG0784	Response regulator, receiver
ISU62_RS13925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU62_RS13940	COG0814	amino acid
ISU62_RS13965	COG0697	spore germination
ISU62_RS13975	COG1982	Orn Lys Arg decarboxylase major
ISU62_RS13980	COG0531	amino acid
ISU62_RS13985	COG1174	glycine betaine transport
ISU62_RS13990	COG1125	glycine betaine transport
ISU62_RS13995	COG1174	glycine betaine transport
ISU62_RS14005	COG2897	thiosulfate sulfurtransferase activity
ISU62_RS14025	COG1122	ATPase activity
ISU62_RS14045	COG4807	Protein conserved in bacteria
ISU62_RS14060	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ISU62_RS14070	COG2261	transglycosylase associated protein
ISU62_RS14090	COG0277	FAD linked oxidase domain protein
ISU62_RS14095	COG1686	Belongs to the peptidase S11 family
ISU62_RS14105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU62_RS14130	COG3328	transposase activity
ISU62_RS14165	COG0513	Belongs to the DEAD box helicase family
ISU62_RS14170	COG1309	transcriptional regulator
ISU62_RS14180	COG1131	(ABC) transporter
ISU62_RS14185	COG0842	Transport permease protein
ISU62_RS14190	COG0842	Transport permease protein
ISU62_RS14210	COG1902	pentaerythritol trinitrate reductase activity
ISU62_RS14240	COG0670	Belongs to the BI1 family
ISU62_RS14245	COG0314	molybdopterin synthase activity
ISU62_RS14250	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ISU62_RS14260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ISU62_RS14265	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ISU62_RS14270	COG4628	conserved protein (DUF2132)
ISU62_RS14280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ISU62_RS14290	COG2226	methyltransferase
ISU62_RS14315	COG0561	phosphatase activity
ISU62_RS14325	COG4149	molybdate abc transporter
ISU62_RS14330	COG0725	ABC transporter, periplasmic molybdate-binding protein
ISU62_RS14340	COG2005	Transcriptional regulator
ISU62_RS14340	COG3585	molybdate ion transport
ISU62_RS14345	COG1119	ATPase activity
ISU62_RS14355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ISU62_RS14360	COG1085	galactose-1-phosphate uridylyltransferase
ISU62_RS14375	COG2017	converts alpha-aldose to the beta-anomer
ISU62_RS14390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU62_RS14395	COG1230	cation diffusion facilitator family transporter
ISU62_RS14425	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ISU62_RS14430	COG2885	chlorophyll binding
ISU62_RS14440	COG3064	Membrane
ISU62_RS14440	COG3064	Membrane
ISU62_RS14445	COG0848	biopolymer transport protein
ISU62_RS14450	COG0811	peptide transport
ISU62_RS14455	COG0824	Thioesterase
ISU62_RS14460	COG3790	cyd operon protein YbgE
ISU62_RS14465	COG4890	Cyd operon protein YbgT
ISU62_RS14470	COG1294	oxidase, subunit
ISU62_RS14475	COG1271	oxidase subunit
ISU62_RS14480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ISU62_RS14490	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU62_RS14505	COG1053	succinate dehydrogenase
ISU62_RS14510	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ISU62_RS14515	COG2009	succinate dehydrogenase
ISU62_RS14530	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ISU62_RS14535	COG0497	DNA recombination
ISU62_RS14540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU62_RS14550	COG2867	negative regulation of translational initiation
ISU62_RS14590	COG1953	Uracil, thiamine, allantoin
ISU62_RS14610	COG2226	methyltransferase
ISU62_RS14615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU62_RS14620	COG1388	LysM domain
ISU62_RS14620	COG0741	lytic transglycosylase activity
ISU62_RS14635	COG0656	L-ascorbic acid biosynthetic process
ISU62_RS14665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU62_RS14675	COG2011	ABC-type metal ion transport system permease component
ISU62_RS14680	COG1464	Belongs to the NlpA lipoprotein family
ISU62_RS14690	COG1720	tRNA m6t6A37 methyltransferase activity
ISU62_RS14700	COG3015	lipoprotein NlpE involved in copper resistance
ISU62_RS14710	COG4681	YaeQ
ISU62_RS14720	COG4568	rho-dependent transcription termination
ISU62_RS14730	COG0037	tRNA processing
ISU62_RS14735	COG0346	lactoylglutathione lyase activity
ISU62_RS14745	COG0587	DNA-directed DNA polymerase activity
ISU62_RS14770	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ISU62_RS14785	COG0750	zinc metalloprotease
ISU62_RS14790	COG0575	Belongs to the CDS family
ISU62_RS14850	COG0564	pseudouridine synthase activity
ISU62_RS14855	COG3098	single-species biofilm formation
ISU62_RS14880	COG1611	Belongs to the LOG family
ISU62_RS14895	COG2363	Small membrane protein
ISU62_RS14900	COG0583	DNA-binding transcription factor activity
ISU62_RS14910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ISU62_RS14915	COG2166	iron-sulfur cluster assembly
ISU62_RS14920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ISU62_RS14925	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ISU62_RS14940	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU62_RS14950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ISU62_RS14955	COG1074	ATP-dependent DNA helicase activity
ISU62_RS14965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ISU62_RS15015	COG0667	Aldo Keto reductase
ISU62_RS15045	COG1609	Transcriptional regulator
ISU62_RS15055	COG0583	DNA-binding transcription factor activity
ISU62_RS15060	COG2814	Major facilitator Superfamily
ISU62_RS15065	COG0583	DNA-binding transcription factor activity
ISU62_RS15080	COG0840	transmembrane signaling receptor activity
ISU62_RS15125	COG2165	general secretion pathway protein
ISU62_RS15145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU62_RS15165	COG0288	reversible hydration of carbon dioxide
ISU62_RS15205	COG3119	arylsulfatase activity
ISU62_RS15210	COG1349	DNA-binding transcription factor activity
ISU62_RS15220	COG2222	sugar isomerase
ISU62_RS15225	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU62_RS15230	COG3715	PTS system
ISU62_RS15235	COG3716	PTS system mannose fructose sorbose family IID component
ISU62_RS15240	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU62_RS15260	COG0641	radical SAM
ISU62_RS15265	COG3119	arylsulfatase activity
ISU62_RS15290	COG2271	Major facilitator Superfamily
ISU62_RS15310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU62_RS15310	COG1263	PTS System
ISU62_RS15315	COG1874	Beta-galactosidase
ISU62_RS15320	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ISU62_RS15325	COG3833	ABC-type maltose transport systems, permease component
ISU62_RS15330	COG1175	transmembrane transport
ISU62_RS15335	COG2182	Extracellular solute-binding protein
ISU62_RS15345	COG1129	ABC transporter
ISU62_RS15350	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS15355	COG1879	ABC-type sugar transport system periplasmic component
ISU62_RS15365	COG0791	NLP P60 protein
ISU62_RS15370	COG1695	Transcriptional regulator
ISU62_RS15460	COG2944	sequence-specific DNA binding
ISU62_RS15485	COG0582	viral genome integration into host DNA
ISU62_RS15505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ISU62_RS15510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU62_RS15515	COG4974	Belongs to the 'phage' integrase family
ISU62_RS15520	COG0716	FMN binding
ISU62_RS15525	COG4452	Inner membrane protein CreD
ISU62_RS15530	COG2205	protein histidine kinase activity
ISU62_RS15535	COG0745	RESPONSE REGULATOR receiver
ISU62_RS15560	COG1272	protein, Hemolysin III
ISU62_RS15605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU62_RS15610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU62_RS15615	COG0006	proline dipeptidase activity
ISU62_RS15635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ISU62_RS15645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISU62_RS15680	COG0191	fructose-bisphosphate aldolase activity
ISU62_RS15715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISU62_RS15720	COG0501	Belongs to the peptidase M48B family
ISU62_RS15735	COG1166	arginine decarboxylase activity
ISU62_RS15750	COG2356	endonuclease I
ISU62_RS15755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ISU62_RS15760	COG0189	ligase activity
ISU62_RS15775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU62_RS15785	COG2805	Type II/IV secretion system protein
ISU62_RS15790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ISU62_RS15795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ISU62_RS15800	COG0762	integral membrane protein
ISU62_RS15810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ISU62_RS15815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU62_RS15845	COG3171	Protein conserved in bacteria
ISU62_RS15855	COG1194	a g-specific adenine glycosylase
ISU62_RS15875	COG4774	siderophore transport
ISU62_RS15880	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS15885	COG1129	ABC transporter
ISU62_RS15890	COG1879	ABC-type sugar transport system periplasmic component
ISU62_RS15895	COG1982	Orn Lys Arg decarboxylase major
ISU62_RS16010	COG3916	Acyl-homoserine-lactone synthase
ISU62_RS16015	COG2771	luxR family
ISU62_RS16065	COG2211	Major facilitator Superfamily
ISU62_RS16075	COG5001	Diguanylate cyclase
ISU62_RS16085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU62_RS16130	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ISU62_RS16135	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU62_RS16140	COG4771	TonB-dependent receptor
ISU62_RS16165	COG1605	Chorismate mutase
ISU62_RS16165	COG0287	Prephenate dehydrogenase
ISU62_RS16170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU62_RS16175	COG3279	Response regulator of the LytR AlgR family
ISU62_RS16185	COG3137	Salt-induced outer membrane protein
ISU62_RS16215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ISU62_RS16220	COG4137	Cytochrome C assembly protein
ISU62_RS16225	COG4536	flavin adenine dinucleotide binding
ISU62_RS16240	COG2918	glutathione biosynthetic process
ISU62_RS16245	COG1238	metal cluster binding
ISU62_RS16250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU62_RS16280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ISU62_RS16320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU62_RS16325	COG3958	Transketolase
ISU62_RS16330	COG3959	Transketolase, thiamine diphosphate binding domain
ISU62_RS16335	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS16340	COG1129	ABC transporter
ISU62_RS16350	COG1879	ABC-type sugar transport system periplasmic component
ISU62_RS16360	COG3783	Cytochrome b(562)
ISU62_RS16365	COG3038	cytochrome b561
ISU62_RS16370	COG3381	protein complex oligomerization
ISU62_RS16375	COG3302	dmso reductase anchor subunit
ISU62_RS16380	COG0437	4 iron, 4 sulfur cluster binding
ISU62_RS16385	COG0243	molybdopterin cofactor binding
ISU62_RS16390	COG0235	Class ii aldolase
ISU62_RS16395	COG1349	DNA-binding transcription factor activity
ISU62_RS16410	COG1129	ABC transporter
ISU62_RS16415	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS16420	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS16425	COG3623	hexulose-6-phosphate isomerase
ISU62_RS16430	COG1070	Carbohydrate kinase
ISU62_RS16435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU62_RS16435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU62_RS16445	COG0024	Methionine aminopeptidase
ISU62_RS16455	COG4771	TonB-dependent receptor
ISU62_RS16465	COG1858	cytochrome C peroxidase
ISU62_RS16470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU62_RS16490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISU62_RS16505	COG2376	Dihydroxyacetone kinase
ISU62_RS16510	COG1028	Short-chain dehydrogenase reductase Sdr
ISU62_RS16515	COG1063	alcohol dehydrogenase
ISU62_RS16520	COG0698	ribose 5-phosphate isomerase
ISU62_RS16530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ISU62_RS16535	COG4942	peptidase
ISU62_RS16535	COG1388	LysM domain
ISU62_RS16575	COG0529	Catalyzes the synthesis of activated sulfate
ISU62_RS16630	COG0720	synthase
ISU62_RS16635	COG0602	queuosine metabolic process
ISU62_RS16655	COG3956	TIGRFAM MazG family protein
ISU62_RS16660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU62_RS16665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ISU62_RS16675	COG3850	Histidine kinase
ISU62_RS16675	COG3437	response regulator, receiver
ISU62_RS16675	COG2205	protein histidine kinase activity
ISU62_RS16675	COG4999	Histidine kinase
ISU62_RS16680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU62_RS16700	COG2860	membrane
ISU62_RS16720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU62_RS16725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU62_RS16730	COG1120	ATPase activity
ISU62_RS16735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ISU62_RS16740	COG1643	Atp-dependent helicase
ISU62_RS16745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ISU62_RS16760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ISU62_RS16765	COG0617	tRNA 3'-terminal CCA addition
ISU62_RS16770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ISU62_RS16795	COG0842	Transport permease protein
ISU62_RS16800	COG1131	(ABC) transporter
ISU62_RS16805	COG0288	reversible hydration of carbon dioxide
ISU62_RS16810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ISU62_RS16815	COG2132	Multicopper oxidase
ISU62_RS16835	COG0697	spore germination
ISU62_RS16845	COG1049	propionate catabolic process, 2-methylcitrate cycle
ISU62_RS16855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU62_RS16860	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU62_RS16865	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ISU62_RS16870	COG2186	Transcriptional regulator
ISU62_RS16875	COG1113	amino acid transport
ISU62_RS16880	COG3725	Membrane protein required for beta-lactamase induction
ISU62_RS16885	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU62_RS16895	COG4969	Belongs to the N-Me-Phe pilin family
ISU62_RS16900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU62_RS16905	COG1459	type II secretion system
ISU62_RS16955	COG0582	viral genome integration into host DNA
ISU62_RS16965	COG0795	lipopolysaccharide-transporting ATPase activity
ISU62_RS16970	COG0795	lipopolysaccharide-transporting ATPase activity
ISU62_RS16980	COG2927	DNA polymerase III (CHI subunit)
ISU62_RS16985	COG0525	valine-tRNA ligase activity
ISU62_RS16995	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ISU62_RS17005	COG2731	YhcH YjgK YiaL family protein
ISU62_RS17015	COG0601	transmembrane transport
ISU62_RS17020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU62_RS17025	COG0444	Belongs to the ABC transporter superfamily
ISU62_RS17030	COG4608	Belongs to the ABC transporter superfamily
ISU62_RS17045	COG2188	Transcriptional regulator
ISU62_RS17050	COG3624	Phosphonate C-P lyase system protein PhnG
ISU62_RS17055	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ISU62_RS17060	COG3626	phosphonate metabolism
ISU62_RS17065	COG3627	carbon phosphorus lyase activity
ISU62_RS17070	COG4107	phosphonate C-P lyase system protein PhnK
ISU62_RS17075	COG4778	phosphonate C-P lyase system protein PhnL
ISU62_RS17080	COG3454	Phosphonate metabolism
ISU62_RS17085	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ISU62_RS17095	COG0702	epimerase
ISU62_RS17110	COG3842	ATPase activity
ISU62_RS17115	COG0395	ABC-type sugar transport system, permease component
ISU62_RS17120	COG1175	transmembrane transport
ISU62_RS17125	COG1653	transport
ISU62_RS17145	COG3153	acetyltransferase
ISU62_RS17150	COG3154	lipid carrier protein
ISU62_RS17155	COG0826	peptidase U32
ISU62_RS17160	COG0826	peptidase U32
ISU62_RS17170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU62_RS17180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISU62_RS17200	COG0513	Belongs to the DEAD box helicase family
ISU62_RS17245	COG0195	Participates in both transcription termination and antitermination
ISU62_RS17265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ISU62_RS17275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ISU62_RS17290	COG1534	Rna-binding protein
ISU62_RS17300	COG2027	D-alanyl-D-alanine carboxypeptidase
ISU62_RS17305	COG0745	RESPONSE REGULATOR receiver
ISU62_RS17310	COG0642	Histidine kinase
ISU62_RS17320	COG0697	spore germination
ISU62_RS17335	COG0142	geranyltranstransferase activity
ISU62_RS17345	COG3423	Transcriptional regulator
ISU62_RS17365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ISU62_RS17370	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ISU62_RS17375	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ISU62_RS17380	COG2105	PFAM AIG2 family protein
ISU62_RS17390	COG0729	surface antigen
ISU62_RS17400	COG1253	flavin adenine dinucleotide binding
ISU62_RS17410	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ISU62_RS17420	COG0737	Belongs to the 5'-nucleotidase family
ISU62_RS17430	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU62_RS17435	COG3061	Opacity-associated protein A
ISU62_RS17455	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ISU62_RS17465	COG0360	Binds together with S18 to 16S ribosomal RNA
ISU62_RS17470	COG1073	alpha beta
ISU62_RS17490	COG3650	response to hydrogen peroxide
ISU62_RS17495	COG1960	acyl-CoA dehydrogenase activity
ISU62_RS17500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU62_RS17505	COG0557	exoribonuclease II activity
ISU62_RS17520	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ISU62_RS17525	COG0330	HflC and HflK could
ISU62_RS17530	COG0330	HflC and HflK could
ISU62_RS17535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ISU62_RS17555	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU62_RS17560	COG0802	atpase or kinase
ISU62_RS17565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ISU62_RS17565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ISU62_RS17570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ISU62_RS17585	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ISU62_RS17600	COG3264	Mechanosensitive ion channel
ISU62_RS17600	COG1511	domain protein
ISU62_RS17620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ISU62_RS17630	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ISU62_RS17675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ISU62_RS17690	COG3383	formate dehydrogenase (NAD+) activity
ISU62_RS17695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU62_RS17700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU62_RS17700	COG0493	'glutamate synthase
ISU62_RS17705	COG1309	transcriptional regulator
ISU62_RS17765	COG1454	alcohol dehydrogenase
ISU62_RS17775	COG0629	single-stranded DNA binding
ISU62_RS17780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ISU62_RS17785	COG2315	Protein conserved in bacteria
ISU62_RS17790	COG1448	Aminotransferase
ISU62_RS17815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU62_RS17820	COG0735	belongs to the Fur family
ISU62_RS17830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ISU62_RS17870	COG3121	Chaperone
ISU62_RS17930	COG1358	cellular component organization or biogenesis
ISU62_RS17955	COG3721	Heme iron utilization protein
ISU62_RS17960	COG0702	epimerase
ISU62_RS17970	COG4771	TonB-dependent receptor
ISU62_RS17975	COG3720	iron ion transport
ISU62_RS17980	COG4558	Periplasmic binding protein
ISU62_RS17985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU62_RS17995	COG0626	cystathionine gamma-synthase activity
ISU62_RS18000	COG0814	amino acid
ISU62_RS18005	COG0583	DNA-binding transcription factor activity
ISU62_RS18010	COG0425	Belongs to the sulfur carrier protein TusA family
ISU62_RS18125	COG1301	dicarboxylic acid transport
ISU62_RS18135	COG3162	membrane
ISU62_RS18195	COG0151	Belongs to the GarS family
ISU62_RS18215	COG1515	deoxyribonuclease V activity
ISU62_RS18250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ISU62_RS18305	COG0250	Participates in transcription elongation, termination and antitermination
ISU62_RS18365	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ISU62_RS18395	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ISU62_RS18400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ISU62_RS18415	COG1739	Uncharacterized protein family UPF0029
ISU62_RS18440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ISU62_RS18475	COG0805	protein transport
ISU62_RS18485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU62_RS18505	COG1322	Protein conserved in bacteria
ISU62_RS18510	COG0586	Pfam SNARE associated Golgi protein
ISU62_RS18515	COG1966	Carbon starvation protein
ISU62_RS18530	COG0412	Dienelactone hydrolase
ISU62_RS18540	COG0583	DNA-binding transcription factor activity
ISU62_RS18545	COG0697	spore germination
ISU62_RS18550	COG0679	Auxin Efflux Carrier
ISU62_RS18555	COG0584	glycerophosphoryl diester phosphodiesterase
ISU62_RS18615	COG0410	ABC transporter
ISU62_RS18625	COG4177	L-phenylalanine transmembrane transporter activity
ISU62_RS18635	COG0683	leucine binding
ISU62_RS18655	COG2177	Part of the ABC transporter FtsEX involved in
ISU62_RS18660	COG2884	Cell division ATP-binding protein ftsE
ISU62_RS18665	COG0552	protein localization to endoplasmic reticulum
ISU62_RS18665	COG0552	protein localization to endoplasmic reticulum
ISU62_RS18670	COG0742	ribosomal rna small subunit methyltransferase
ISU62_RS18675	COG3776	membrane
ISU62_RS18690	COG3714	YhhN family
ISU62_RS18705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ISU62_RS18715	COG0247	lactate metabolic process
ISU62_RS18725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU62_RS18730	COG0584	glycerophosphoryl diester phosphodiesterase
ISU62_RS18740	COG0561	phosphatase activity
ISU62_RS18745	COG2267	carboxylic ester hydrolase activity
ISU62_RS18750	COG1280	lysine exporter protein (LysE YggA)
ISU62_RS18755	COG1280	lysine exporter protein (LysE YggA)
ISU62_RS18760	COG0514	ATP-dependent DNA helicase (RecQ)
ISU62_RS18765	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ISU62_RS18770	COG2050	protein possibly involved in aromatic compounds catabolism
ISU62_RS18785	COG5564	TIM-barrel signal transduction protein
ISU62_RS18790	COG5441	Belongs to the UPF0261 family
ISU62_RS18800	COG0210	DNA helicase
ISU62_RS18805	COG1011	Hydrolase
ISU62_RS18810	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ISU62_RS18815	COG3159	Protein conserved in bacteria
ISU62_RS18835	COG3072	Adenylate cyclase
ISU62_RS18850	COG1587	Uroporphyrinogen-III synthase
ISU62_RS18855	COG2959	enzyme of heme biosynthesis
ISU62_RS18860	COG3071	HemY protein
ISU62_RS18890	COG1113	amino acid transport
ISU62_RS18910	COG2244	polysaccharide biosynthetic process
ISU62_RS18915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ISU62_RS18920	COG0456	acetyltransferase
ISU62_RS18925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ISU62_RS18930	COG1088	dTDP-glucose 4,6-dehydratase activity
ISU62_RS18935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ISU62_RS18940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ISU62_RS18945	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU62_RS18950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ISU62_RS18955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ISU62_RS18960	COG3118	belongs to the thioredoxin family
ISU62_RS18985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU62_RS18995	COG3328	transposase activity
ISU62_RS19005	COG3121	Chaperone
ISU62_RS19020	COG3121	Chaperone
ISU62_RS19055	COG0583	DNA-binding transcription factor activity
ISU62_RS19100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU62_RS19105	COG3978	acetolactate synthase activity
ISU62_RS19125	COG3085	chromosome segregation
ISU62_RS19135	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS19140	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS19145	COG1129	ABC transporter
ISU62_RS19150	COG1879	ABC-type sugar transport system periplasmic component
ISU62_RS19220	COG0678	peroxiredoxin activity
ISU62_RS19220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU62_RS19225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU62_RS19250	COG1629	transport
ISU62_RS19265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ISU62_RS19300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU62_RS19305	COG0058	SHG alpha-glucan phosphorylase activity
ISU62_RS19330	COG3275	phosphorelay sensor kinase activity
ISU62_RS19365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU62_RS19370	COG2095	MarC family integral membrane protein
ISU62_RS19385	COG3265	gluconokinase activity
ISU62_RS19390	COG2610	gluconate transmembrane transporter activity
ISU62_RS19395	COG1609	Transcriptional regulator
ISU62_RS19400	COG1741	Belongs to the pirin family
ISU62_RS19420	COG0191	fructose-bisphosphate aldolase activity
ISU62_RS19435	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU62_RS19450	COG2081	HI0933 family
ISU62_RS19455	COG0306	phosphate transporter
ISU62_RS19470	COG0589	response to stress
ISU62_RS19490	COG0339	signal peptide processing
ISU62_RS19495	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ISU62_RS19500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU62_RS19505	COG3835	regulator
ISU62_RS19515	COG2610	gluconate transmembrane transporter activity
ISU62_RS19520	COG1929	Belongs to the glycerate kinase type-1 family
ISU62_RS19545	COG1295	ribonuclease BN
ISU62_RS19550	COG2134	cdp-diacylglycerol pyrophosphatase
ISU62_RS19555	COG2982	Protein involved in outer membrane biogenesis
ISU62_RS19560	COG2200	EAL domain
ISU62_RS19565	COG1942	4-Oxalocrotonate Tautomerase
ISU62_RS19570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU62_RS19575	COG0612	Peptidase, M16
ISU62_RS19595	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU62_RS19600	COG2200	EAL domain
ISU62_RS19600	COG2199	diguanylate cyclase activity
ISU62_RS19605	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ISU62_RS19610	COG4608	Belongs to the ABC transporter superfamily
ISU62_RS19615	COG0444	Belongs to the ABC transporter superfamily
ISU62_RS19620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU62_RS19625	COG0601	transmembrane transport
ISU62_RS19630	COG0747	negative chemotaxis
ISU62_RS19635	COG2831	hemolysin activation secretion protein
ISU62_RS19650	COG2271	Major facilitator Superfamily
ISU62_RS19675	COG2197	response regulator
ISU62_RS19680	COG2194	sulfuric ester hydrolase activity
ISU62_RS19695	COG2986	histidine ammonia-lyase
ISU62_RS19725	COG4607	ABC-type enterochelin transport system periplasmic component
ISU62_RS19735	COG4605	iron ion homeostasis
ISU62_RS19740	COG4604	ABC transporter, ATP-binding protein
ISU62_RS19785	COG0582	viral genome integration into host DNA
ISU62_RS19795	COG1609	Transcriptional regulator
ISU62_RS19795	COG2207	Transcriptional regulator
ISU62_RS19800	COG4214	carbohydrate transport
ISU62_RS19810	COG4213	ABC transporter substrate-binding protein
ISU62_RS19820	COG1070	Carbohydrate kinase
ISU62_RS19830	COG3121	Chaperone
ISU62_RS19845	COG3274	enterobacterial common antigen metabolic process
ISU62_RS19865	COG0527	aspartate kinase activity
ISU62_RS19865	COG0460	homoserine dehydrogenase
ISU62_RS19880	COG4682	membrane
ISU62_RS19890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ISU62_RS19895	COG1609	Transcriptional regulator
ISU62_RS19900	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU62_RS19915	COG1575	Belongs to the MenA family. Type 1 subfamily
ISU62_RS19955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ISU62_RS19960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU62_RS19965	COG1494	fructose-1,6-bisphosphatase
ISU62_RS19975	COG3152	Membrane
ISU62_RS19990	COG0583	DNA-binding transcription factor activity
ISU62_RS19995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ISU62_RS20000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISU62_RS20005	COG0471	metal ion transport
ISU62_RS20015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ISU62_RS20040	COG3678	ATP-independent chaperone mediated protein folding
ISU62_RS20045	COG0745	RESPONSE REGULATOR receiver
ISU62_RS20050	COG2205	protein histidine kinase activity
ISU62_RS20055	COG2169	Transcriptional regulator
ISU62_RS20055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU62_RS20060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ISU62_RS20065	COG1045	serine acetyltransferase
ISU62_RS20080	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU62_RS20085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ISU62_RS20095	COG4942	peptidase
ISU62_RS20110	COG0156	8-amino-7-oxononanoate synthase activity
ISU62_RS20120	COG0859	PFAM glycosyl transferase family 9
ISU62_RS20125	COG0859	PFAM glycosyl transferase family 9
ISU62_RS20130	COG1519	Transferase
ISU62_RS20165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ISU62_RS20190	COG1561	YicC-like family, N-terminal region
ISU62_RS20195	COG2860	membrane
ISU62_RS20215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU62_RS20220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU62_RS20225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ISU62_RS20235	COG0786	glutamate:sodium symporter activity
ISU62_RS20240	COG2233	PERMEase
ISU62_RS20245	COG2982	Protein involved in outer membrane biogenesis
ISU62_RS20250	COG0456	acetyltransferase
ISU62_RS20275	COG1011	Hydrolase
ISU62_RS20285	COG0174	glutamine synthetase
ISU62_RS20290	COG3852	Histidine kinase
ISU62_RS20300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU62_RS20320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU62_RS20320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU62_RS20325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU62_RS20330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ISU62_RS20335	COG3084	Protein conserved in bacteria
ISU62_RS20345	COG1763	Mo-molybdopterin cofactor biosynthetic process
ISU62_RS20350	COG3328	transposase activity
ISU62_RS20375	COG2186	Transcriptional regulator
ISU62_RS20380	COG0477	Major facilitator Superfamily
ISU62_RS20395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU62_RS20425	COG1522	sequence-specific DNA binding
ISU62_RS20430	COG0716	FMN binding
ISU62_RS20445	COG3312	ion transport
ISU62_RS20500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ISU62_RS20505	COG0573	inorganic phosphate transmembrane transporter activity
ISU62_RS20510	COG0581	inorganic phosphate transmembrane transporter activity
ISU62_RS20520	COG0704	Plays a role in the regulation of phosphate uptake
ISU62_RS20530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU62_RS20535	COG0765	amino acid transport
ISU62_RS20540	COG0765	amino acid transport
ISU62_RS20545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU62_RS20555	COG2252	PERMEase
ISU62_RS20585	COG0706	membrane insertase activity
ISU62_RS20600	COG0230	Belongs to the bacterial ribosomal protein bL34 family