locus-tag	class	description
CH63_RS00205	COG0582	viral genome integration into host DNA
CH63_RS00550	COG2766	serine protein kinase
CH63_RS00590	COG0616	signal peptide processing
CH63_RS00685	COG1737	Transcriptional regulator
CH63_RS00885	COG3328	transposase activity
CH63_RS01075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH63_RS01085	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH63_RS01090	COG0739	heme binding
CH63_RS01095	COG1560	Kdo2-lipid A biosynthetic process
CH63_RS01100	COG0469	pyruvate kinase activity
CH63_RS01105	COG1737	Transcriptional regulator
CH63_RS01110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH63_RS01115	COG0800	Aldolase
CH63_RS01130	COG0251	oxidation-reduction process
CH63_RS01135	COG1199	ATP-dependent helicase activity
CH63_RS01145	COG3065	identical protein binding
CH63_RS01150	COG0318	PFAM AMP-dependent synthetase and ligase
CH63_RS01155	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH63_RS01160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH63_RS01165	COG2894	cell division
CH63_RS01180	COG2951	lytic endotransglycosylase activity
CH63_RS01185	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH63_RS01290	COG3328	transposase activity
CH63_RS01455	COG3328	transposase activity
CH63_RS01465	COG1104	cysteine desulfurase activity
CH63_RS01495	COG2719	SpoVR family
CH63_RS01505	COG2814	Major facilitator Superfamily
CH63_RS01515	COG0583	DNA-binding transcription factor activity
CH63_RS01530	COG2766	serine protein kinase
CH63_RS01535	COG3713	MltA-interacting MipA family protein
CH63_RS01555	COG3139	Protein of unknown function (DUF1315)
CH63_RS01560	COG1335	isochorismatase
CH63_RS01565	COG0252	asparaginase activity
CH63_RS01570	COG0616	signal peptide processing
CH63_RS01575	COG0778	Nitroreductase
CH63_RS01580	COG0709	Synthesizes selenophosphate from selenide and ATP
CH63_RS01585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH63_RS01595	COG0494	nUDIX hydrolase
CH63_RS01600	COG0708	Exodeoxyribonuclease III
CH63_RS01605	COG0583	DNA-binding transcription factor activity
CH63_RS01615	COG3328	transposase activity
CH63_RS01620	COG0788	formyltetrahydrofolate deformylase activity
CH63_RS01630	COG0745	RESPONSE REGULATOR receiver
CH63_RS01680	COG3121	Chaperone
CH63_RS01705	COG2995	paraquat-inducible protein a
CH63_RS01710	COG1956	GAF domain-containing protein
CH63_RS01720	COG0793	Belongs to the peptidase S41A family
CH63_RS01730	COG3539	Fimbrial protein
CH63_RS01735	COG3121	Chaperone
CH63_RS01750	COG3121	Chaperone
CH63_RS01755	COG2814	Major facilitator Superfamily
CH63_RS01760	COG0823	Involved in the tonB-independent uptake of proteins
CH63_RS01770	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH63_RS01775	COG1823	symporter activity
CH63_RS01780	COG1988	membrane-bound metal-dependent
CH63_RS01785	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH63_RS01790	COG1653	transport
CH63_RS01795	COG3842	ATPase activity
CH63_RS01800	COG0395	ABC-type sugar transport system, permease component
CH63_RS01805	COG1175	transmembrane transport
CH63_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS01825	COG1917	Cupin 2, conserved barrel domain protein
CH63_RS01830	COG3328	transposase activity
CH63_RS01835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH63_RS01845	COG3001	Fructosamine kinase
CH63_RS01855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH63_RS01860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH63_RS01865	COG1121	(ABC) transporter
CH63_RS01870	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH63_RS01895	COG4249	Peptidase C14 caspase catalytic subunit p20
CH63_RS01925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH63_RS01925	COG0072	phenylalanine-tRNA ligase activity
CH63_RS01930	COG0776	regulation of translation
CH63_RS01945	COG0386	Belongs to the glutathione peroxidase family
CH63_RS01990	COG0791	NLP P60 protein
CH63_RS02015	COG0574	Belongs to the PEP-utilizing enzyme family
CH63_RS02015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH63_RS02020	COG0628	permease
CH63_RS02025	COG0247	lactate metabolic process
CH63_RS02025	COG0277	FAD linked oxidase domain protein
CH63_RS02030	COG2050	protein possibly involved in aromatic compounds catabolism
CH63_RS02040	COG0316	Belongs to the HesB IscA family
CH63_RS02045	COG0719	Fe-S assembly protein
CH63_RS02050	COG0396	ATPase activity
CH63_RS02055	COG0719	Fe-S assembly protein
CH63_RS02070	COG1388	LysM domain
CH63_RS02070	COG1376	ErfK ybiS ycfS ynhG family protein
CH63_RS02120	COG0307	riboflavin synthase, alpha
CH63_RS02125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH63_RS02130	COG2814	Major facilitator Superfamily
CH63_RS02135	COG0583	DNA-binding transcription factor activity
CH63_RS02145	COG0791	NLP P60 protein
CH63_RS02155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH63_RS02160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH63_RS02165	COG0346	lactoylglutathione lyase activity
CH63_RS02175	COG1902	pentaerythritol trinitrate reductase activity
CH63_RS02180	COG1309	transcriptional regulator
CH63_RS02185	COG2194	sulfuric ester hydrolase activity
CH63_RS02195	COG3133	Outer membrane lipoprotein
CH63_RS02205	COG3895	Periplasmic Protein
CH63_RS02225	COG0625	glutathione transferase activity
CH63_RS02240	COG3104	oligopeptide transport
CH63_RS02245	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH63_RS02245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH63_RS02250	COG4172	Belongs to the ABC transporter superfamily
CH63_RS02260	COG4171	peptide transport system, permease
CH63_RS02265	COG4168	peptide transport system, permease
CH63_RS02270	COG4166	transmembrane transport
CH63_RS02290	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH63_RS02295	COG1842	Phage shock protein A
CH63_RS02305	COG1983	PspC domain protein
CH63_RS02315	COG3106	COG3106 Predicted ATPase
CH63_RS02325	COG5654	RES domain protein
CH63_RS02330	COG5642	Protein of unknown function (DUF2384)
CH63_RS02345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH63_RS02350	COG4948	Mandelate Racemase Muconate Lactonizing
CH63_RS02355	COG2866	Carboxypeptidase
CH63_RS02360	COG4166	transmembrane transport
CH63_RS02375	COG0657	acetylesterase activity
CH63_RS02385	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH63_RS02385	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH63_RS02385	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH63_RS02385	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH63_RS02395	COG1285	pathogenesis
CH63_RS02400	COG3042	response to heat
CH63_RS02405	COG3187	Heat shock protein
CH63_RS02410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH63_RS02415	COG2911	Protein conserved in bacteria
CH63_RS02425	COG3784	Protein of unknown function (DUF1318)
CH63_RS02430	COG0246	Mannitol dehydrogenase
CH63_RS02435	COG2390	Transcriptional regulator
CH63_RS02445	COG1643	Atp-dependent helicase
CH63_RS02460	COG3591	Belongs to the peptidase S1B family
CH63_RS02505	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH63_RS02510	COG2205	protein histidine kinase activity
CH63_RS02515	COG0745	RESPONSE REGULATOR receiver
CH63_RS02525	COG0531	amino acid
CH63_RS02540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH63_RS02545	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH63_RS02550	COG0589	response to stress
CH63_RS02555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH63_RS02560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH63_RS02580	COG1011	Hydrolase
CH63_RS02585	COG0440	acetolactate synthase activity
CH63_RS02615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH63_RS02625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH63_RS02645	COG1609	Transcriptional regulator
CH63_RS02655	COG0038	chloride channel
CH63_RS02660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH63_RS02665	COG1940	carbohydrate kinase activity
CH63_RS02670	COG0583	DNA-binding transcription factor activity
CH63_RS02685	COG0114	fumarate hydratase activity
CH63_RS02695	COG5339	Protein conserved in bacteria
CH63_RS02705	COG0385	Bile acid
CH63_RS02710	COG0673	inositol 2-dehydrogenase activity
CH63_RS02720	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS02725	COG1129	ABC transporter
CH63_RS02730	COG1879	ABC-type sugar transport system periplasmic component
CH63_RS02745	COG2274	protein secretion by the type I secretion system
CH63_RS02750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_RS02760	COG1132	(ABC) transporter
CH63_RS02790	COG3708	Transcriptional regulator
CH63_RS02790	COG2207	Transcriptional regulator
CH63_RS02795	COG4658	electron transport chain
CH63_RS02800	COG4659	FMN binding
CH63_RS02810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH63_RS02815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_RS02820	COG2271	Major facilitator Superfamily
CH63_RS02830	COG1966	Carbon starvation protein
CH63_RS02835	COG2879	small protein
CH63_RS02840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH63_RS02860	COG0023	Translation Initiation Factor
CH63_RS02875	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH63_RS02880	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH63_RS02885	COG0671	phosphoesterase, PA-phosphatase related
CH63_RS02895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH63_RS02905	COG0583	DNA-binding transcription factor activity
CH63_RS02925	COG0616	signal peptide processing
CH63_RS02930	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS02940	COG1187	pseudouridine synthase activity
CH63_RS02945	COG0009	L-threonylcarbamoyladenylate synthase
CH63_RS02970	COG0512	Glutamine amidotransferase of anthranilate synthase
CH63_RS02980	COG0134	indole-3-glycerol-phosphate synthase activity
CH63_RS02980	COG0135	phosphoribosylanthranilate isomerase activity
CH63_RS03000	COG3047	cAMP biosynthetic process
CH63_RS03040	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH63_RS03045	COG2350	Protein conserved in bacteria
CH63_RS03080	COG4608	Belongs to the ABC transporter superfamily
CH63_RS03085	COG0444	Belongs to the ABC transporter superfamily
CH63_RS03090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH63_RS03095	COG0601	transmembrane transport
CH63_RS03105	COG2095	MarC family integral membrane protein
CH63_RS03110	COG1012	belongs to the aldehyde dehydrogenase family
CH63_RS03110	COG1454	alcohol dehydrogenase
CH63_RS03150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH63_RS03160	COG5295	Hep Hag repeat protein
CH63_RS03170	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH63_RS03180	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH63_RS03185	COG0745	RESPONSE REGULATOR receiver
CH63_RS03195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH63_RS03200	COG0840	transmembrane signaling receptor activity
CH63_RS03205	COG0840	transmembrane signaling receptor activity
CH63_RS03225	COG2964	Protein conserved in bacteria
CH63_RS03235	COG0251	oxidation-reduction process
CH63_RS03240	COG2271	Major facilitator Superfamily
CH63_RS03245	COG0835	chemotaxis
CH63_RS03250	COG2198	Histidine kinase
CH63_RS03250	COG0643	Histidine kinase
CH63_RS03255	COG1360	Flagellar Motor Protein
CH63_RS03280	COG1285	pathogenesis
CH63_RS03310	COG0604	alcohol dehydrogenase
CH63_RS03310	COG3321	synthase
CH63_RS03310	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS03320	COG1522	sequence-specific DNA binding
CH63_RS03345	COG1733	regulation of RNA biosynthetic process
CH63_RS03350	COG0702	epimerase
CH63_RS03355	COG0840	transmembrane signaling receptor activity
CH63_RS03370	COG0538	isocitrate dehydrogenase activity
CH63_RS03375	COG1187	pseudouridine synthase activity
CH63_RS03395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH63_RS03405	COG0745	RESPONSE REGULATOR receiver
CH63_RS03415	COG2850	peptidyl-arginine hydroxylation
CH63_RS03430	COG1940	carbohydrate kinase activity
CH63_RS03435	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH63_RS03445	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH63_RS03450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH63_RS03455	COG3134	Outer membrane lipoprotein
CH63_RS03460	COG3328	transposase activity
CH63_RS03475	COG1252	NADH dehydrogenase
CH63_RS03485	COG1472	Belongs to the glycosyl hydrolase 3 family
CH63_RS03500	COG5633	Lipoprotein
CH63_RS03505	COG0537	adenosine 5'-monophosphoramidase activity
CH63_RS03510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH63_RS03520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_RS03520	COG1263	PTS System
CH63_RS03525	COG0084	hydrolase, TatD family'
CH63_RS03530	COG0470	DNA polymerase III
CH63_RS03540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH63_RS03545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH63_RS03555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_RS03585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH63_RS03590	COG1399	metal-binding, possibly nucleic acid-binding protein
CH63_RS03595	COG0424	maF-like protein
CH63_RS03600	COG0564	pseudouridine synthase activity
CH63_RS03605	COG1530	ribonuclease E activity
CH63_RS03610	COG3328	transposase activity
CH63_RS03615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH63_RS03640	COG3328	transposase activity
CH63_RS03655	COG0628	permease
CH63_RS03685	COG3916	Acyl-homoserine-lactone synthase
CH63_RS03690	COG2771	luxR family
CH63_RS03695	COG0583	DNA-binding transcription factor activity
CH63_RS03705	COG0477	Major facilitator Superfamily
CH63_RS03740	COG1203	CRISPR-associated helicase, Cas3
CH63_RS03745	COG1518	maintenance of DNA repeat elements
CH63_RS03755	COG0668	transmembrane transport
CH63_RS03775	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH63_RS03780	COG0395	ABC-type sugar transport system, permease component
CH63_RS03795	COG1609	Transcriptional regulator
CH63_RS03805	COG3842	ATPase activity
CH63_RS03815	COG3210	domain, Protein
CH63_RS03835	COG3210	domain, Protein
CH63_RS03860	COG2831	hemolysin activation secretion protein
CH63_RS03865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_RS03875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH63_RS03885	COG0473	3-isopropylmalate dehydrogenase activity
CH63_RS03890	COG0583	DNA-binding transcription factor activity
CH63_RS03895	COG1609	Transcriptional regulator
CH63_RS03900	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS03905	COG1129	ABC transporter
CH63_RS03910	COG1879	ABC-type sugar transport system periplasmic component
CH63_RS03915	COG1063	alcohol dehydrogenase
CH63_RS03935	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH63_RS03965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_RS03970	COG0765	amino acid transport
CH63_RS03975	COG1126	abc transporter atp-binding protein
CH63_RS04005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH63_RS04020	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH63_RS04035	COG1169	isochorismate synthase
CH63_RS04045	COG4575	ribosome binding
CH63_RS04060	COG0129	dihydroxy-acid dehydratase activity
CH63_RS04075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH63_RS04085	COG1609	Transcriptional regulator
CH63_RS04090	COG1649	PFAM Uncharacterised BCR, COG1649
CH63_RS04095	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS04100	COG3265	gluconokinase activity
CH63_RS04105	COG2731	YhcH YjgK YiaL family protein
CH63_RS04120	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH63_RS04125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH63_RS04135	COG0839	Belongs to the complex I subunit 6 family
CH63_RS04150	COG1034	ATP synthesis coupled electron transport
CH63_RS04170	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH63_RS04180	COG0583	DNA-binding transcription factor activity
CH63_RS04190	COG0436	Aminotransferase
CH63_RS04205	COG0490	domain, Protein
CH63_RS04205	COG0471	metal ion transport
CH63_RS04210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH63_RS04235	COG0280	phosphate acetyltransferase
CH63_RS04235	COG0857	belongs to the CobB CobQ family
CH63_RS04240	COG1609	Transcriptional regulator
CH63_RS04255	COG3328	transposase activity
CH63_RS04260	COG3037	sugar-specific permease SgaT UlaA
CH63_RS04265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH63_RS04270	COG0622	Phosphoesterase
CH63_RS04280	COG1090	epimerase
CH63_RS04285	COG4598	ABC transporter
CH63_RS04290	COG4160	amino acid transport
CH63_RS04295	COG4215	(ABC) transporter
CH63_RS04300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_RS04310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH63_RS04315	COG1286	toxin biosynthetic process
CH63_RS04320	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH63_RS04325	COG0285	dihydrofolate synthase activity
CH63_RS04335	COG0586	Pfam SNARE associated Golgi protein
CH63_RS04345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH63_RS04365	COG0697	spore germination
CH63_RS04380	COG1794	racemase activity, acting on amino acids and derivatives
CH63_RS04385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_RS04400	COG3101	peptidyl-lysine hydroxylation
CH63_RS04405	COG0730	response to heat
CH63_RS04420	COG2890	protein-(glutamine-N5) methyltransferase activity
CH63_RS04435	COG2062	phosphohistidine phosphatase, SixA
CH63_RS04450	COG3691	Protein conserved in bacteria
CH63_RS04465	COG3088	subunit of a heme lyase
CH63_RS04465	COG4235	cytochrome complex assembly
CH63_RS04470	COG3088	subunit of a heme lyase
CH63_RS04470	COG4235	cytochrome complex assembly
CH63_RS04475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH63_RS04480	COG1138	Cytochrome C-type biogenesis protein
CH63_RS04490	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH63_RS04495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH63_RS04500	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH63_RS04520	COG1704	LemA family
CH63_RS04530	COG2824	Alkylphosphonate utilization operon protein PhnA
CH63_RS04620	COG3188	usher protein
CH63_RS04625	COG3328	transposase activity
CH63_RS04630	COG3188	usher protein
CH63_RS04635	COG3121	Chaperone
CH63_RS04695	COG2951	lytic endotransglycosylase activity
CH63_RS04730	COG0243	molybdopterin cofactor binding
CH63_RS04735	COG0437	4 iron, 4 sulfur cluster binding
CH63_RS04740	COG3302	dmso reductase anchor subunit
CH63_RS04745	COG3381	protein complex oligomerization
CH63_RS04775	COG3038	cytochrome b561
CH63_RS04780	COG0436	Aminotransferase
CH63_RS04805	COG0667	Aldo Keto reductase
CH63_RS04820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH63_RS04870	COG3530	Putative quorum-sensing-regulated virulence factor
CH63_RS04885	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH63_RS04895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_RS04935	COG2205	protein histidine kinase activity
CH63_RS04940	COG0745	RESPONSE REGULATOR receiver
CH63_RS04945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_RS04960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH63_RS04980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH63_RS04990	COG5002	protein histidine kinase activity
CH63_RS04990	COG3850	Histidine kinase
CH63_RS04995	COG0745	RESPONSE REGULATOR receiver
CH63_RS05010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH63_RS05015	COG4208	sulfate ABC transporter
CH63_RS05020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH63_RS05035	COG1737	Transcriptional regulator
CH63_RS05045	COG2731	YhcH YjgK YiaL family protein
CH63_RS05055	COG4886	Leucine-rich repeat (LRR) protein
CH63_RS05065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH63_RS05070	COG2837	iron assimilation
CH63_RS05080	COG3111	PFAM Bacterial OB fold (BOF) protein
CH63_RS05125	COG3005	denitrification pathway
CH63_RS05130	COG3043	anaerobic respiration
CH63_RS05140	COG3062	negative regulation of establishment of protein localization
CH63_RS05145	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_RS05145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_RS05150	COG2197	response regulator
CH63_RS05170	COG1988	membrane-bound metal-dependent
CH63_RS05175	COG0641	radical SAM
CH63_RS05180	COG3119	arylsulfatase activity
CH63_RS05185	COG3842	ATPase activity
CH63_RS05190	COG1175	transmembrane transport
CH63_RS05205	COG1393	Belongs to the ArsC family
CH63_RS05215	COG1876	peptidase activity
CH63_RS05235	COG2321	neutral zinc metallopeptidase
CH63_RS05255	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH63_RS05265	COG2716	regulation of RNA biosynthetic process
CH63_RS05270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH63_RS05290	COG0628	permease
CH63_RS05295	COG4783	chaperone-mediated protein folding
CH63_RS05300	COG1393	Belongs to the ArsC family
CH63_RS05325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH63_RS05330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH63_RS05350	COG0581	inorganic phosphate transmembrane transporter activity
CH63_RS05360	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH63_RS05375	COG2239	Acts as a magnesium transporter
CH63_RS05380	COG0443	Heat shock 70 kDa protein
CH63_RS05385	COG1177	transmembrane transport
CH63_RS05390	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH63_RS05400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH63_RS05410	COG3842	ATPase activity
CH63_RS05435	COG2205	protein histidine kinase activity
CH63_RS05440	COG2205	protein histidine kinase activity
CH63_RS05445	COG0745	RESPONSE REGULATOR receiver
CH63_RS05450	COG3422	double-strand break repair
CH63_RS05455	COG0826	peptidase U32
CH63_RS05475	COG0351	phosphomethylpyrimidine kinase
CH63_RS05490	COG3328	transposase activity
CH63_RS05525	COG0513	Belongs to the DEAD box helicase family
CH63_RS05530	COG1309	transcriptional regulator
CH63_RS05540	COG1131	(ABC) transporter
CH63_RS05545	COG0842	Transport permease protein
CH63_RS05550	COG0842	Transport permease protein
CH63_RS05570	COG1902	pentaerythritol trinitrate reductase activity
CH63_RS05590	COG2211	Major facilitator Superfamily
CH63_RS05600	COG2211	Major facilitator Superfamily
CH63_RS05605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH63_RS05615	COG0583	DNA-binding transcription factor activity
CH63_RS05620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH63_RS05650	COG0670	Belongs to the BI1 family
CH63_RS05655	COG0314	molybdopterin synthase activity
CH63_RS05660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH63_RS05670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH63_RS05680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH63_RS05685	COG4628	conserved protein (DUF2132)
CH63_RS05695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CH63_RS05705	COG2226	methyltransferase
CH63_RS05730	COG0561	phosphatase activity
CH63_RS05740	COG4149	molybdate abc transporter
CH63_RS05745	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH63_RS05755	COG2005	Transcriptional regulator
CH63_RS05755	COG3585	molybdate ion transport
CH63_RS05760	COG1119	ATPase activity
CH63_RS05775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH63_RS05780	COG1085	galactose-1-phosphate uridylyltransferase
CH63_RS05795	COG2017	converts alpha-aldose to the beta-anomer
CH63_RS05810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH63_RS05815	COG1230	cation diffusion facilitator family transporter
CH63_RS05845	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH63_RS05850	COG2885	chlorophyll binding
CH63_RS05860	COG3064	Membrane
CH63_RS05860	COG3064	Membrane
CH63_RS05865	COG0848	biopolymer transport protein
CH63_RS05870	COG0811	peptide transport
CH63_RS05875	COG0824	Thioesterase
CH63_RS05880	COG3790	cyd operon protein YbgE
CH63_RS05885	COG4890	Cyd operon protein YbgT
CH63_RS05890	COG1294	oxidase, subunit
CH63_RS05895	COG1271	oxidase subunit
CH63_RS05900	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH63_RS05910	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH63_RS05915	COG0567	Dehydrogenase, E1 component
CH63_RS05925	COG1053	succinate dehydrogenase
CH63_RS05930	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH63_RS05935	COG2009	succinate dehydrogenase
CH63_RS05950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH63_RS05955	COG0497	DNA recombination
CH63_RS05960	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH63_RS05970	COG2867	negative regulation of translational initiation
CH63_RS05990	COG0582	viral genome integration into host DNA
CH63_RS06050	COG3657	addiction module killer protein
CH63_RS06080	COG1953	Uracil, thiamine, allantoin
CH63_RS06100	COG2226	methyltransferase
CH63_RS06105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH63_RS06110	COG0741	lytic transglycosylase activity
CH63_RS06110	COG1388	LysM domain
CH63_RS06125	COG0656	L-ascorbic acid biosynthetic process
CH63_RS06160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH63_RS06170	COG2011	ABC-type metal ion transport system permease component
CH63_RS06175	COG1464	Belongs to the NlpA lipoprotein family
CH63_RS06185	COG1720	tRNA m6t6A37 methyltransferase activity
CH63_RS06195	COG3015	lipoprotein NlpE involved in copper resistance
CH63_RS06205	COG4681	YaeQ
CH63_RS06215	COG4568	rho-dependent transcription termination
CH63_RS06225	COG0037	tRNA processing
CH63_RS06230	COG0346	lactoylglutathione lyase activity
CH63_RS06240	COG0587	DNA-directed DNA polymerase activity
CH63_RS06265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH63_RS06280	COG0750	zinc metalloprotease
CH63_RS06285	COG0575	Belongs to the CDS family
CH63_RS06350	COG0564	pseudouridine synthase activity
CH63_RS06355	COG3098	single-species biofilm formation
CH63_RS06375	COG1611	Belongs to the LOG family
CH63_RS06390	COG2363	Small membrane protein
CH63_RS06395	COG0583	DNA-binding transcription factor activity
CH63_RS06400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH63_RS06405	COG2166	iron-sulfur cluster assembly
CH63_RS06410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH63_RS06415	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH63_RS06430	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH63_RS06440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH63_RS06445	COG1074	ATP-dependent DNA helicase activity
CH63_RS06455	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH63_RS06520	COG0667	Aldo Keto reductase
CH63_RS06555	COG1609	Transcriptional regulator
CH63_RS06565	COG0583	DNA-binding transcription factor activity
CH63_RS06575	COG0583	DNA-binding transcription factor activity
CH63_RS06660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH63_RS06680	COG0288	reversible hydration of carbon dioxide
CH63_RS06725	COG3119	arylsulfatase activity
CH63_RS06730	COG1349	DNA-binding transcription factor activity
CH63_RS06740	COG2222	sugar isomerase
CH63_RS06745	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_RS06750	COG3715	PTS system
CH63_RS06755	COG3716	PTS system mannose fructose sorbose family IID component
CH63_RS06760	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_RS06780	COG0641	radical SAM
CH63_RS06785	COG3119	arylsulfatase activity
CH63_RS06815	COG2271	Major facilitator Superfamily
CH63_RS06835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_RS06835	COG1263	PTS System
CH63_RS06840	COG1874	Beta-galactosidase
CH63_RS06845	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH63_RS06850	COG3833	ABC-type maltose transport systems, permease component
CH63_RS06855	COG1175	transmembrane transport
CH63_RS06860	COG2182	Extracellular solute-binding protein
CH63_RS06870	COG1129	ABC transporter
CH63_RS06875	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS06880	COG1879	ABC-type sugar transport system periplasmic component
CH63_RS06890	COG0791	NLP P60 protein
CH63_RS06895	COG1695	Transcriptional regulator
CH63_RS06990	COG2944	sequence-specific DNA binding
CH63_RS07020	COG0582	viral genome integration into host DNA
CH63_RS07040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH63_RS07045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH63_RS07050	COG4974	Belongs to the 'phage' integrase family
CH63_RS07055	COG0716	FMN binding
CH63_RS07060	COG4452	Inner membrane protein CreD
CH63_RS07065	COG2205	protein histidine kinase activity
CH63_RS07070	COG0745	RESPONSE REGULATOR receiver
CH63_RS07095	COG1272	protein, Hemolysin III
CH63_RS07105	COG5295	Hep Hag repeat protein
CH63_RS07135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH63_RS07140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH63_RS07145	COG0006	proline dipeptidase activity
CH63_RS07160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH63_RS07165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH63_RS07200	COG0191	fructose-bisphosphate aldolase activity
CH63_RS07220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH63_RS07225	COG0501	Belongs to the peptidase M48B family
CH63_RS07235	COG1166	arginine decarboxylase activity
CH63_RS07250	COG2356	endonuclease I
CH63_RS07255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH63_RS07260	COG0189	ligase activity
CH63_RS07275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH63_RS07285	COG2805	Type II/IV secretion system protein
CH63_RS07290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH63_RS07295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH63_RS07300	COG0762	integral membrane protein
CH63_RS07310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH63_RS07315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH63_RS07320	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH63_RS07320	COG3064	Membrane
CH63_RS07320	COG1073	alpha beta
CH63_RS07340	COG3171	Protein conserved in bacteria
CH63_RS07350	COG1194	a g-specific adenine glycosylase
CH63_RS07370	COG4774	siderophore transport
CH63_RS07375	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS07380	COG1129	ABC transporter
CH63_RS07385	COG1879	ABC-type sugar transport system periplasmic component
CH63_RS07390	COG1982	Orn Lys Arg decarboxylase major
CH63_RS07525	COG3916	Acyl-homoserine-lactone synthase
CH63_RS07530	COG2771	luxR family
CH63_RS07580	COG2211	Major facilitator Superfamily
CH63_RS07590	COG2801	Transposase and inactivated derivatives
CH63_RS07605	COG0471	metal ion transport
CH63_RS07630	COG3501	Rhs element vgr protein
CH63_RS07655	COG2610	gluconate transmembrane transporter activity
CH63_RS07670	COG1132	(ABC) transporter
CH63_RS07675	COG2375	cellular response to nickel ion
CH63_RS07675	COG1132	(ABC) transporter
CH63_RS07715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH63_RS07715	COG2226	methyltransferase
CH63_RS07715	COG3433	isochorismatase activity
CH63_RS07740	COG3162	membrane
CH63_RS07750	COG1301	dicarboxylic acid transport
CH63_RS07860	COG2391	methyltransferase activity
CH63_RS07865	COG0425	Belongs to the sulfur carrier protein TusA family
CH63_RS07870	COG0583	DNA-binding transcription factor activity
CH63_RS07875	COG0814	amino acid
CH63_RS07880	COG0626	cystathionine gamma-synthase activity
CH63_RS07890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_RS07895	COG4558	Periplasmic binding protein
CH63_RS07900	COG3720	iron ion transport
CH63_RS07905	COG4771	TonB-dependent receptor
CH63_RS07910	COG0702	epimerase
CH63_RS07915	COG3721	Heme iron utilization protein
CH63_RS07940	COG1358	cellular component organization or biogenesis
CH63_RS08000	COG3121	Chaperone
CH63_RS08045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH63_RS08055	COG0735	belongs to the Fur family
CH63_RS08060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH63_RS08085	COG1448	Aminotransferase
CH63_RS08090	COG2315	Protein conserved in bacteria
CH63_RS08095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH63_RS08100	COG0629	single-stranded DNA binding
CH63_RS08110	COG1454	alcohol dehydrogenase
CH63_RS08180	COG1309	transcriptional regulator
CH63_RS08185	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_RS08185	COG0493	'glutamate synthase
CH63_RS08190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_RS08210	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH63_RS08255	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH63_RS08265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH63_RS08270	COG1053	succinate dehydrogenase
CH63_RS08285	COG3264	Mechanosensitive ion channel
CH63_RS08285	COG1511	domain protein
CH63_RS08305	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH63_RS08325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH63_RS08330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH63_RS08330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH63_RS08335	COG0802	atpase or kinase
CH63_RS08340	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH63_RS08360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH63_RS08365	COG0330	HflC and HflK could
CH63_RS08370	COG0330	HflC and HflK could
CH63_RS08375	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH63_RS08390	COG0557	exoribonuclease II activity
CH63_RS08395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH63_RS08400	COG1960	acyl-CoA dehydrogenase activity
CH63_RS08405	COG3650	response to hydrogen peroxide
CH63_RS08430	COG1073	alpha beta
CH63_RS08440	COG0360	Binds together with S18 to 16S ribosomal RNA
CH63_RS08450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH63_RS08475	COG3061	Opacity-associated protein A
CH63_RS08480	COG0545	Peptidyl-prolyl cis-trans isomerase
CH63_RS08490	COG0737	Belongs to the 5'-nucleotidase family
CH63_RS08500	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH63_RS08510	COG1253	flavin adenine dinucleotide binding
CH63_RS08520	COG0729	surface antigen
CH63_RS08530	COG2105	PFAM AIG2 family protein
CH63_RS08535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH63_RS08540	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH63_RS08545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH63_RS08570	COG3423	Transcriptional regulator
CH63_RS08580	COG0142	geranyltranstransferase activity
CH63_RS08595	COG0697	spore germination
CH63_RS08605	COG0642	Histidine kinase
CH63_RS08610	COG0745	RESPONSE REGULATOR receiver
CH63_RS08615	COG2027	D-alanyl-D-alanine carboxypeptidase
CH63_RS08625	COG1534	Rna-binding protein
CH63_RS08640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH63_RS08650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH63_RS08670	COG0195	Participates in both transcription termination and antitermination
CH63_RS08700	COG2801	Transposase and inactivated derivatives
CH63_RS08705	COG5001	Diguanylate cyclase
CH63_RS08715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_RS08755	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH63_RS08760	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH63_RS08765	COG4771	TonB-dependent receptor
CH63_RS08785	COG2801	Transposase and inactivated derivatives
CH63_RS08830	COG0151	Belongs to the GarS family
CH63_RS08850	COG1515	deoxyribonuclease V activity
CH63_RS08890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH63_RS08955	COG0250	Participates in transcription elongation, termination and antitermination
CH63_RS09015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH63_RS09050	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH63_RS09055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH63_RS09060	COG1739	Uncharacterized protein family UPF0029
CH63_RS09070	COG1739	Uncharacterized protein family UPF0029
CH63_RS09095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH63_RS09130	COG0805	protein transport
CH63_RS09140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH63_RS09160	COG1322	Protein conserved in bacteria
CH63_RS09165	COG0586	Pfam SNARE associated Golgi protein
CH63_RS09170	COG1966	Carbon starvation protein
CH63_RS09185	COG0412	Dienelactone hydrolase
CH63_RS09195	COG0583	DNA-binding transcription factor activity
CH63_RS09200	COG0697	spore germination
CH63_RS09205	COG0679	Auxin Efflux Carrier
CH63_RS09210	COG0584	glycerophosphoryl diester phosphodiesterase
CH63_RS09270	COG0410	ABC transporter
CH63_RS09280	COG4177	L-phenylalanine transmembrane transporter activity
CH63_RS09290	COG0683	leucine binding
CH63_RS09315	COG2177	Part of the ABC transporter FtsEX involved in
CH63_RS09320	COG2884	Cell division ATP-binding protein ftsE
CH63_RS09325	COG0552	protein localization to endoplasmic reticulum
CH63_RS09325	COG0552	protein localization to endoplasmic reticulum
CH63_RS09335	COG0742	ribosomal rna small subunit methyltransferase
CH63_RS09340	COG3776	membrane
CH63_RS09355	COG3714	YhhN family
CH63_RS09370	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH63_RS09380	COG0247	lactate metabolic process
CH63_RS09390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH63_RS09400	COG0584	glycerophosphoryl diester phosphodiesterase
CH63_RS09410	COG0561	phosphatase activity
CH63_RS09415	COG2267	carboxylic ester hydrolase activity
CH63_RS09420	COG1280	lysine exporter protein (LysE YggA)
CH63_RS09425	COG1280	lysine exporter protein (LysE YggA)
CH63_RS09430	COG0514	ATP-dependent DNA helicase (RecQ)
CH63_RS09440	COG2050	protein possibly involved in aromatic compounds catabolism
CH63_RS09455	COG5564	TIM-barrel signal transduction protein
CH63_RS09460	COG5441	Belongs to the UPF0261 family
CH63_RS09470	COG0210	DNA helicase
CH63_RS09475	COG1011	Hydrolase
CH63_RS09480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH63_RS09485	COG3159	Protein conserved in bacteria
CH63_RS09505	COG3072	Adenylate cyclase
CH63_RS09520	COG1587	Uroporphyrinogen-III synthase
CH63_RS09525	COG2959	enzyme of heme biosynthesis
CH63_RS09530	COG3071	HemY protein
CH63_RS09560	COG1113	amino acid transport
CH63_RS09580	COG2244	polysaccharide biosynthetic process
CH63_RS09585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH63_RS09590	COG0456	acetyltransferase
CH63_RS09595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH63_RS09600	COG1088	dTDP-glucose 4,6-dehydratase activity
CH63_RS09605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH63_RS09610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH63_RS09615	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH63_RS09620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH63_RS09625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH63_RS09630	COG3118	belongs to the thioredoxin family
CH63_RS09660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH63_RS09670	COG3328	transposase activity
CH63_RS09685	COG3121	Chaperone
CH63_RS09700	COG3121	Chaperone
CH63_RS09740	COG0583	DNA-binding transcription factor activity
CH63_RS09780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH63_RS09785	COG3978	acetolactate synthase activity
CH63_RS09800	COG3085	chromosome segregation
CH63_RS09810	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS09815	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS09820	COG1129	ABC transporter
CH63_RS09825	COG1879	ABC-type sugar transport system periplasmic component
CH63_RS09905	COG0678	peroxiredoxin activity
CH63_RS09905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH63_RS09910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH63_RS09955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH63_RS09975	COG2801	Transposase and inactivated derivatives
CH63_RS09985	COG0527	aspartate kinase activity
CH63_RS09985	COG0460	homoserine dehydrogenase
CH63_RS10005	COG4682	membrane
CH63_RS10015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH63_RS10025	COG1609	Transcriptional regulator
CH63_RS10030	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH63_RS10045	COG1575	Belongs to the MenA family. Type 1 subfamily
CH63_RS10100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH63_RS10105	COG1494	fructose-1,6-bisphosphatase
CH63_RS10115	COG3152	Membrane
CH63_RS10130	COG0583	DNA-binding transcription factor activity
CH63_RS10135	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH63_RS10140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH63_RS10145	COG0471	metal ion transport
CH63_RS10155	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH63_RS10175	COG3678	ATP-independent chaperone mediated protein folding
CH63_RS10180	COG0745	RESPONSE REGULATOR receiver
CH63_RS10185	COG2205	protein histidine kinase activity
CH63_RS10190	COG2169	Transcriptional regulator
CH63_RS10190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH63_RS10195	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH63_RS10200	COG1045	serine acetyltransferase
CH63_RS10220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH63_RS10225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH63_RS10235	COG4942	peptidase
CH63_RS10250	COG0156	8-amino-7-oxononanoate synthase activity
CH63_RS10260	COG0859	PFAM glycosyl transferase family 9
CH63_RS10265	COG0859	PFAM glycosyl transferase family 9
CH63_RS10270	COG1519	Transferase
CH63_RS10305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH63_RS10330	COG1561	YicC-like family, N-terminal region
CH63_RS10335	COG2860	membrane
CH63_RS10355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH63_RS10360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH63_RS10365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH63_RS10370	COG0786	glutamate:sodium symporter activity
CH63_RS10375	COG2233	PERMEase
CH63_RS10380	COG2982	Protein involved in outer membrane biogenesis
CH63_RS10385	COG0456	acetyltransferase
CH63_RS10405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH63_RS10420	COG0551	DNA topoisomerase type I activity
CH63_RS10430	COG0758	DNA mediated transformation
CH63_RS10460	COG3036	rescue of stalled ribosome
CH63_RS10465	COG0789	Transcriptional regulator
CH63_RS10480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH63_RS10495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH63_RS10500	COG0201	protein transport
CH63_RS10510	COG1841	ribosomal large subunit assembly
CH63_RS10550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH63_RS10555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH63_RS10565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH63_RS10570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH63_RS10580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH63_RS10590	COG0089	rRNA binding
CH63_RS10605	COG0051	transcription antitermination factor activity, RNA binding
CH63_RS10635	COG0049	tRNA binding
CH63_RS10640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH63_RS10660	COG2964	Protein conserved in bacteria
CH63_RS10665	COG0545	Peptidyl-prolyl cis-trans isomerase
CH63_RS10675	COG1047	Peptidyl-prolyl cis-trans
CH63_RS10680	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH63_RS10700	COG1216	Glycosyl transferase, family 2
CH63_RS10710	COG2175	clavaminate synthase activity
CH63_RS10715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH63_RS10725	COG4521	taurine ABC transporter
CH63_RS10735	COG0429	hydrolase of the alpha beta-hydrolase fold
CH63_RS10745	COG3954	Phosphoribulokinase
CH63_RS10755	COG1765	OsmC-like protein
CH63_RS10765	COG1289	transmembrane transporter activity
CH63_RS10780	COG0433	COG0433 Predicted ATPase
CH63_RS10785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH63_RS10790	COG1486	melibiose metabolic process
CH63_RS10810	COG0402	S-adenosylhomocysteine deaminase activity
CH63_RS10815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH63_RS10835	COG0180	Tryptophanyl-tRNA synthetase
CH63_RS10840	COG0546	phosphoglycolate phosphatase activity
CH63_RS10845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH63_RS10870	COG4796	Type ii and iii secretion system protein
CH63_RS10900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH63_RS10905	COG0494	nUDIX hydrolase
CH63_RS10920	COG1011	Hydrolase
CH63_RS10925	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH63_RS10950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH63_RS10955	COG2183	response to ionizing radiation
CH63_RS10965	COG1918	ferrous iron import across plasma membrane
CH63_RS11000	COG1640	4-alpha-glucanotransferase
CH63_RS11005	COG0058	SHG alpha-glucan phosphorylase activity
CH63_RS11010	COG0058	SHG alpha-glucan phosphorylase activity
CH63_RS11030	COG1349	DNA-binding transcription factor activity
CH63_RS11040	COG2801	Transposase and inactivated derivatives
CH63_RS11115	COG1175	transmembrane transport
CH63_RS11120	COG3833	ABC-type maltose transport systems, permease component
CH63_RS11135	COG0527	aspartate kinase activity
CH63_RS11160	COG1414	Transcriptional regulator
CH63_RS11165	COG1414	Transcriptional regulator
CH63_RS11175	COG2224	Isocitrate lyase
CH63_RS11180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH63_RS11230	COG2186	Transcriptional regulator
CH63_RS11235	COG0477	Major facilitator Superfamily
CH63_RS11245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_RS11275	COG1522	sequence-specific DNA binding
CH63_RS11280	COG0716	FMN binding
CH63_RS11295	COG3312	ion transport
CH63_RS11350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH63_RS11355	COG0573	inorganic phosphate transmembrane transporter activity
CH63_RS11360	COG0581	inorganic phosphate transmembrane transporter activity
CH63_RS11370	COG0704	Plays a role in the regulation of phosphate uptake
CH63_RS11380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_RS11385	COG0765	amino acid transport
CH63_RS11390	COG0765	amino acid transport
CH63_RS11395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH63_RS11400	COG2252	PERMEase
CH63_RS11425	COG0706	membrane insertase activity
CH63_RS11435	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH63_RS11445	COG0592	DNA-directed DNA polymerase activity
CH63_RS11460	COG0187	DNA topoisomerase II activity
CH63_RS11465	COG0561	phosphatase activity
CH63_RS11470	COG2801	Transposase and inactivated derivatives
CH63_RS11480	COG2423	ornithine cyclodeaminase activity
CH63_RS11485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH63_RS11490	COG0823	Involved in the tonB-independent uptake of proteins
CH63_RS11495	COG0823	Involved in the tonB-independent uptake of proteins
CH63_RS11500	COG5645	(Lipo)protein
CH63_RS11520	COG3977	Valine--pyruvate aminotransferase
CH63_RS11530	COG0366	Alpha amylase catalytic
CH63_RS11545	COG2885	chlorophyll binding
CH63_RS11555	COG2818	Glycosylase
CH63_RS11575	COG2213	PTS system mannitol-specific
CH63_RS11575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_RS11585	COG3722	fumarate hydratase activity
CH63_RS11610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH63_RS11620	COG0243	molybdopterin cofactor binding
CH63_RS11620	COG3383	formate dehydrogenase (NAD+) activity
CH63_RS11625	COG0243	molybdopterin cofactor binding
CH63_RS11625	COG3383	formate dehydrogenase (NAD+) activity
CH63_RS11630	COG0437	4 iron, 4 sulfur cluster binding
CH63_RS11635	COG2864	formate dehydrogenase
CH63_RS11650	COG3276	selenocysteine insertion sequence binding
CH63_RS11655	COG3276	selenocysteine insertion sequence binding
CH63_RS11690	COG2801	Transposase and inactivated derivatives
CH63_RS11705	COG3274	enterobacterial common antigen metabolic process
CH63_RS11725	COG3121	Chaperone
CH63_RS11735	COG1070	Carbohydrate kinase
CH63_RS11745	COG4213	ABC transporter substrate-binding protein
CH63_RS11755	COG4214	carbohydrate transport
CH63_RS11760	COG1609	Transcriptional regulator
CH63_RS11760	COG2207	Transcriptional regulator
CH63_RS11765	COG0582	viral genome integration into host DNA
CH63_RS11805	COG4604	ABC transporter, ATP-binding protein
CH63_RS11810	COG4605	iron ion homeostasis
CH63_RS11820	COG4607	ABC-type enterochelin transport system periplasmic component
CH63_RS11850	COG2986	histidine ammonia-lyase
CH63_RS11865	COG2194	sulfuric ester hydrolase activity
CH63_RS11870	COG2197	response regulator
CH63_RS11885	COG2271	Major facilitator Superfamily
CH63_RS11910	COG2831	hemolysin activation secretion protein
CH63_RS11920	COG0747	negative chemotaxis
CH63_RS11925	COG0601	transmembrane transport
CH63_RS11930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH63_RS11935	COG0444	Belongs to the ABC transporter superfamily
CH63_RS11940	COG4608	Belongs to the ABC transporter superfamily
CH63_RS11945	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH63_RS11950	COG2199	diguanylate cyclase activity
CH63_RS11950	COG2200	EAL domain
CH63_RS11955	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH63_RS11975	COG0612	Peptidase, M16
CH63_RS11980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_RS11985	COG1942	4-Oxalocrotonate Tautomerase
CH63_RS11990	COG2200	EAL domain
CH63_RS12000	COG2134	cdp-diacylglycerol pyrophosphatase
CH63_RS12005	COG1295	ribonuclease BN
CH63_RS12030	COG1929	Belongs to the glycerate kinase type-1 family
CH63_RS12035	COG2610	gluconate transmembrane transporter activity
CH63_RS12040	COG3835	regulator
CH63_RS12045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH63_RS12050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH63_RS12055	COG0339	signal peptide processing
CH63_RS12075	COG0589	response to stress
CH63_RS12095	COG0306	phosphate transporter
CH63_RS12100	COG2081	HI0933 family
CH63_RS12115	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS12130	COG0191	fructose-bisphosphate aldolase activity
CH63_RS12150	COG1741	Belongs to the pirin family
CH63_RS12155	COG1609	Transcriptional regulator
CH63_RS12160	COG2610	gluconate transmembrane transporter activity
CH63_RS12165	COG3265	gluconokinase activity
CH63_RS12185	COG2095	MarC family integral membrane protein
CH63_RS12190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH63_RS12220	COG3275	phosphorelay sensor kinase activity
CH63_RS12245	COG0058	SHG alpha-glucan phosphorylase activity
CH63_RS12250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH63_RS12270	COG2801	Transposase and inactivated derivatives
CH63_RS12345	COG3501	Rhs element vgr protein
CH63_RS12355	COG3209	COG3209 Rhs family protein
CH63_RS12375	COG0673	inositol 2-dehydrogenase activity
CH63_RS12380	COG2207	Transcriptional regulator
CH63_RS12380	COG1917	Cupin 2, conserved barrel domain protein
CH63_RS12385	COG1869	D-ribose catabolic process
CH63_RS12390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_RS12395	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH63_RS12400	COG0431	NADPH-dependent FMN reductase
CH63_RS12405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH63_RS12415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH63_RS12425	COG3077	Addiction module antitoxin, RelB DinJ family
CH63_RS12430	COG2252	PERMEase
CH63_RS12435	COG0025	NhaP-type Na H and K H
CH63_RS12445	COG1560	Kdo2-lipid A biosynthetic process
CH63_RS12455	COG1129	ABC transporter
CH63_RS12460	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS12470	COG1069	ribulokinase activity
CH63_RS12480	COG0625	glutathione transferase activity
CH63_RS12505	COG1278	Cold shock
CH63_RS12510	COG1278	Cold shock
CH63_RS12520	COG3133	Outer membrane lipoprotein
CH63_RS12525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH63_RS12535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH63_RS12555	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH63_RS12560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH63_RS12570	COG4145	pantothenate transmembrane transporter activity
CH63_RS12575	COG3924	membrane
CH63_RS12580	COG0439	Biotin carboxylase
CH63_RS12585	COG0511	ligase activity, forming carbon-carbon bonds
CH63_RS12600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH63_RS12605	COG0604	alcohol dehydrogenase
CH63_RS12610	COG2199	diguanylate cyclase activity
CH63_RS12610	COG2200	EAL domain
CH63_RS12615	COG1077	Cell shape determining protein MreB Mrl
CH63_RS12620	COG1792	Involved in formation and maintenance of cell shape
CH63_RS12625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH63_RS12630	COG0424	maF-like protein
CH63_RS12635	COG1530	ribonuclease E activity
CH63_RS12640	COG3164	Protein of unknown function
CH63_RS12645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH63_RS12650	COG0312	modulator of DNA gyrase
CH63_RS12705	COG0583	DNA-binding transcription factor activity
CH63_RS12725	COG1012	belongs to the aldehyde dehydrogenase family
CH63_RS12740	COG2732	(Barnase) inhibitor
CH63_RS12750	COG0312	modulator of DNA gyrase
CH63_RS12760	COG3783	Cytochrome b(562)
CH63_RS12765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH63_RS12770	COG0366	Alpha amylase catalytic
CH63_RS12775	COG1263	PTS System
CH63_RS12775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_RS12780	COG1609	Transcriptional regulator
CH63_RS12805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_RS12825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH63_RS12830	COG1137	ATPase activity
CH63_RS12835	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH63_RS12840	COG3117	lipopolysaccharide transmembrane transporter activity
CH63_RS12845	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH63_RS12850	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH63_RS12850	COG0517	IMP dehydrogenase activity
CH63_RS12855	COG0530	calcium, potassium:sodium antiporter activity
CH63_RS12860	COG1127	ABC transporter
CH63_RS12865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH63_RS12870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH63_RS12875	COG2854	intermembrane phospholipid transfer
CH63_RS12880	COG3113	response to antibiotic
CH63_RS12885	COG5007	Belongs to the BolA IbaG family
CH63_RS12895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH63_RS12905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH63_RS12910	COG3105	Protein conserved in bacteria
CH63_RS12915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH63_RS12935	COG0625	glutathione transferase activity
CH63_RS12940	COG2969	positive regulation of protein catabolic process
CH63_RS12950	COG0493	'glutamate synthase
CH63_RS12955	COG0070	glutamate synthase
CH63_RS12955	COG0069	glutamate synthase activity
CH63_RS12955	COG0067	glutamate synthase
CH63_RS12960	COG1242	4 iron, 4 sulfur cluster binding
CH63_RS12970	COG0784	Response regulator, receiver
CH63_RS12970	COG5002	protein histidine kinase activity
CH63_RS12970	COG2198	Histidine kinase
CH63_RS12980	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH63_RS12990	COG2823	Periplasmic or secreted lipoprotein
CH63_RS13010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH63_RS13015	COG1741	Belongs to the pirin family
CH63_RS13020	COG0583	DNA-binding transcription factor activity
CH63_RS13025	COG0435	Glutathione S-transferase
CH63_RS13070	COG3328	transposase activity
CH63_RS13075	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH63_RS13085	COG3084	Protein conserved in bacteria
CH63_RS13090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH63_RS13095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH63_RS13100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH63_RS13100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH63_RS13135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH63_RS13145	COG3852	Histidine kinase
CH63_RS13150	COG0174	glutamine synthetase
CH63_RS13165	COG1011	Hydrolase
CH63_RS13190	COG1401	restriction endodeoxyribonuclease activity
CH63_RS13205	COG2963	transposase activity
CH63_RS13260	COG4269	membrane
CH63_RS13270	COG2207	Transcriptional regulator
CH63_RS13275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH63_RS13280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH63_RS13285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH63_RS13290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_RS13290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH63_RS13290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_RS13340	COG1070	Carbohydrate kinase
CH63_RS13345	COG0859	PFAM glycosyl transferase family 9
CH63_RS13365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_RS13370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_RS13415	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH63_RS13420	COG0456	acetyltransferase
CH63_RS13430	COG2823	Periplasmic or secreted lipoprotein
CH63_RS13450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH63_RS13480	COG3726	membrane protein affecting hemolysin expression
CH63_RS13485	COG0560	Phosphoserine phosphatase
CH63_RS13510	COG2885	chlorophyll binding
CH63_RS13515	COG2199	diguanylate cyclase activity
CH63_RS13530	COG0741	lytic transglycosylase activity
CH63_RS13535	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH63_RS13550	COG2207	Transcriptional regulator
CH63_RS13550	COG3708	Transcriptional regulator
CH63_RS13555	COG3045	CreA protein
CH63_RS13560	COG0745	RESPONSE REGULATOR receiver
CH63_RS13590	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH63_RS13605	COG1584	GPR1 FUN34 yaaH family protein
CH63_RS13625	COG0583	DNA-binding transcription factor activity
CH63_RS13640	COG0196	riboflavin kinase activity
CH63_RS13655	COG1047	Peptidyl-prolyl cis-trans
CH63_RS13690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH63_RS13695	COG1280	lysine exporter protein (LysE YggA)
CH63_RS13700	COG2966	Psort location CytoplasmicMembrane, score
CH63_RS13710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH63_RS13730	COG2721	sulfolactate sulfo-lyase activity
CH63_RS13750	COG2271	Major facilitator Superfamily
CH63_RS13765	COG0586	Pfam SNARE associated Golgi protein
CH63_RS13785	COG4575	ribosome binding
CH63_RS13790	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH63_RS13800	COG2259	Doxx family
CH63_RS13805	COG0435	Glutathione S-transferase
CH63_RS13820	COG0494	nUDIX hydrolase
CH63_RS13845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH63_RS13850	COG0849	cell division
CH63_RS13855	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH63_RS13875	COG0772	Belongs to the SEDS family
CH63_RS13890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH63_RS13895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH63_RS13900	COG0768	penicillin binding
CH63_RS13905	COG3116	cell division
CH63_RS13925	COG1609	Transcriptional regulator
CH63_RS13945	COG0028	Belongs to the TPP enzyme family
CH63_RS13955	COG1022	Amp-dependent synthetase and ligase
CH63_RS13985	COG0473	3-isopropylmalate dehydrogenase activity
CH63_RS14000	COG2814	Major facilitator Superfamily
CH63_RS14020	COG4143	(ABC) transporter
CH63_RS14025	COG1178	ABC-type Fe3 transport system permease component
CH63_RS14030	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CH63_RS14035	COG0586	Pfam SNARE associated Golgi protein
CH63_RS14040	COG0417	DNA replication proofreading
CH63_RS14145	COG0564	pseudouridine synthase activity
CH63_RS14150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH63_RS14210	COG0673	inositol 2-dehydrogenase activity
CH63_RS14215	COG1451	nucleotide metabolic process
CH63_RS14230	COG1902	pentaerythritol trinitrate reductase activity
CH63_RS14230	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH63_RS14235	COG3247	response to pH
CH63_RS14255	COG4245	von Willebrand factor, type A
CH63_RS14270	COG4245	von Willebrand factor, type A
CH63_RS14275	COG2831	hemolysin activation secretion protein
CH63_RS14305	COG3210	domain, Protein
CH63_RS14310	COG3210	domain, Protein
CH63_RS14330	COG3842	ATPase activity
CH63_RS14335	COG3459	Glycosyltransferase 36 associated
CH63_RS14340	COG1609	Transcriptional regulator
CH63_RS14345	COG2182	Extracellular solute-binding protein
CH63_RS14355	COG0395	ABC-type sugar transport system, permease component
CH63_RS14375	COG1289	transmembrane transporter activity
CH63_RS14400	COG0436	Aminotransferase
CH63_RS14420	COG0251	oxidation-reduction process
CH63_RS14505	COG0358	DNA primase activity
CH63_RS14510	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CH63_RS14525	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH63_RS14540	COG4991	sh3 domain protein
CH63_RS14545	COG3025	triphosphatase activity
CH63_RS14560	COG0531	amino acid
CH63_RS14580	COG3384	dioxygenase
CH63_RS14585	COG0754	glutathionylspermidine amidase activity
CH63_RS14600	COG1538	Outer membrane efflux protein
CH63_RS14605	COG0494	nUDIX hydrolase
CH63_RS14610	COG3151	Protein conserved in bacteria
CH63_RS14615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH63_RS14620	COG3150	esterase
CH63_RS14630	COG0583	DNA-binding transcription factor activity
CH63_RS14635	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH63_RS14640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH63_RS14650	COG2132	Multicopper oxidase
CH63_RS14660	COG0656	L-ascorbic acid biosynthetic process
CH63_RS14670	COG1979	alcohol dehydrogenase
CH63_RS14675	COG2207	Transcriptional regulator
CH63_RS14680	COG0586	Pfam SNARE associated Golgi protein
CH63_RS14685	COG0626	cystathionine gamma-synthase activity
CH63_RS14690	COG0811	peptide transport
CH63_RS14695	COG0848	biopolymer transport protein
CH63_RS14745	COG4964	Belongs to the GSP D family
CH63_RS14750	COG4964	Belongs to the GSP D family
CH63_RS14785	COG4592	Periplasmic binding protein
CH63_RS14805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH63_RS14810	COG1684	flagellar biosynthetic protein fliR
CH63_RS14815	COG1987	bacterial-type flagellum assembly
CH63_RS14840	COG1677	Flagellar hook-basal body complex protein FliE
CH63_RS14880	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH63_RS14885	COG1815	bacterial-type flagellum-dependent cell motility
CH63_RS14890	COG1558	bacterial-type flagellum-dependent cell motility
CH63_RS14895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH63_RS14900	COG1749	Flagellar hook protein flgE
CH63_RS14905	COG4787	bacterial-type flagellum-dependent cell motility
CH63_RS14910	COG4786	Flagellar basal body rod
CH63_RS14920	COG1706	bacterial-type flagellum-dependent cell motility
CH63_RS14930	COG1256	bacterial-type flagellum assembly
CH63_RS14950	COG3710	Transcriptional regulator
CH63_RS14965	COG2801	Transposase and inactivated derivatives
CH63_RS14980	COG0513	Belongs to the DEAD box helicase family
CH63_RS15000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH63_RS15010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_RS15020	COG0826	peptidase U32
CH63_RS15025	COG0826	peptidase U32
CH63_RS15035	COG3154	lipid carrier protein
CH63_RS15040	COG3153	acetyltransferase
CH63_RS15060	COG1653	transport
CH63_RS15065	COG1175	transmembrane transport
CH63_RS15070	COG0395	ABC-type sugar transport system, permease component
CH63_RS15075	COG3842	ATPase activity
CH63_RS15090	COG0702	epimerase
CH63_RS15095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH63_RS15100	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH63_RS15105	COG3454	Phosphonate metabolism
CH63_RS15110	COG4778	phosphonate C-P lyase system protein PhnL
CH63_RS15115	COG4107	phosphonate C-P lyase system protein PhnK
CH63_RS15120	COG3627	carbon phosphorus lyase activity
CH63_RS15125	COG3626	phosphonate metabolism
CH63_RS15135	COG3624	Phosphonate C-P lyase system protein PhnG
CH63_RS15140	COG2188	Transcriptional regulator
CH63_RS15155	COG4608	Belongs to the ABC transporter superfamily
CH63_RS15160	COG0444	Belongs to the ABC transporter superfamily
CH63_RS15165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH63_RS15170	COG0601	transmembrane transport
CH63_RS15180	COG2731	YhcH YjgK YiaL family protein
CH63_RS15190	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH63_RS15200	COG0525	valine-tRNA ligase activity
CH63_RS15205	COG2927	DNA polymerase III (CHI subunit)
CH63_RS15215	COG0795	lipopolysaccharide-transporting ATPase activity
CH63_RS15220	COG0795	lipopolysaccharide-transporting ATPase activity
CH63_RS15230	COG0582	viral genome integration into host DNA
CH63_RS15285	COG1459	type II secretion system
CH63_RS15290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH63_RS15295	COG4969	Belongs to the N-Me-Phe pilin family
CH63_RS15305	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH63_RS15315	COG1113	amino acid transport
CH63_RS15320	COG2186	Transcriptional regulator
CH63_RS15325	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH63_RS15330	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH63_RS15335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH63_RS15350	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH63_RS15380	COG2132	Multicopper oxidase
CH63_RS15385	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH63_RS15390	COG0288	reversible hydration of carbon dioxide
CH63_RS15395	COG1131	(ABC) transporter
CH63_RS15400	COG0842	Transport permease protein
CH63_RS15425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH63_RS15430	COG0617	tRNA 3'-terminal CCA addition
CH63_RS15435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH63_RS15450	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH63_RS15455	COG1643	Atp-dependent helicase
CH63_RS15460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH63_RS15465	COG1120	ATPase activity
CH63_RS15470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH63_RS15475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_RS15495	COG2860	membrane
CH63_RS15515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH63_RS15520	COG2205	protein histidine kinase activity
CH63_RS15520	COG3437	response regulator, receiver
CH63_RS15520	COG3850	Histidine kinase
CH63_RS15520	COG4999	Histidine kinase
CH63_RS15525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH63_RS15535	COG3956	TIGRFAM MazG family protein
CH63_RS15555	COG0602	queuosine metabolic process
CH63_RS15560	COG0720	synthase
CH63_RS15610	COG0529	Catalyzes the synthesis of activated sulfate
CH63_RS15650	COG1388	LysM domain
CH63_RS15650	COG4942	peptidase
CH63_RS15655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH63_RS15670	COG0698	ribose 5-phosphate isomerase
CH63_RS15675	COG1063	alcohol dehydrogenase
CH63_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS15685	COG2376	Dihydroxyacetone kinase
CH63_RS15700	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH63_RS15720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_RS15725	COG1858	cytochrome C peroxidase
CH63_RS15730	COG4771	TonB-dependent receptor
CH63_RS15745	COG0024	Methionine aminopeptidase
CH63_RS15755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH63_RS15755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH63_RS15760	COG1070	Carbohydrate kinase
CH63_RS15765	COG3623	hexulose-6-phosphate isomerase
CH63_RS15770	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS15775	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS15780	COG1129	ABC transporter
CH63_RS15795	COG1349	DNA-binding transcription factor activity
CH63_RS15800	COG0235	Class ii aldolase
CH63_RS15805	COG0243	molybdopterin cofactor binding
CH63_RS15810	COG0437	4 iron, 4 sulfur cluster binding
CH63_RS15815	COG3302	dmso reductase anchor subunit
CH63_RS15820	COG3381	protein complex oligomerization
CH63_RS15825	COG3038	cytochrome b561
CH63_RS15830	COG3783	Cytochrome b(562)
CH63_RS15840	COG1879	ABC-type sugar transport system periplasmic component
CH63_RS15850	COG1129	ABC transporter
CH63_RS15855	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS15860	COG3959	Transketolase, thiamine diphosphate binding domain
CH63_RS15865	COG3958	Transketolase
CH63_RS15870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH63_RS15910	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH63_RS15935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH63_RS15940	COG1238	metal cluster binding
CH63_RS15945	COG2918	glutathione biosynthetic process
CH63_RS15965	COG4536	flavin adenine dinucleotide binding
CH63_RS15970	COG4137	Cytochrome C assembly protein
CH63_RS15975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH63_RS16010	COG3137	Salt-induced outer membrane protein
CH63_RS16015	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH63_RS16020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH63_RS16025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH63_RS16030	COG3279	Response regulator of the LytR AlgR family
CH63_RS16035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH63_RS16040	COG0287	Prephenate dehydrogenase
CH63_RS16040	COG1605	Chorismate mutase
CH63_RS16045	COG1605	Chorismate mutase
CH63_RS16045	COG0077	Prephenate dehydratase
CH63_RS16060	COG0077	Prephenate dehydratase
CH63_RS16060	COG1605	Chorismate mutase
CH63_RS16075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH63_RS16080	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH63_RS16085	COG0564	pseudouridine synthase activity
CH63_RS16095	COG0542	response to heat
CH63_RS16135	COG5544	Lipoprotein
CH63_RS16140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH63_RS16145	COG0045	succinate-CoA ligase (ADP-forming) activity
CH63_RS16145	COG1042	CoA-binding domain protein
CH63_RS16145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH63_RS16150	COG3148	PFAM DTW domain containing protein
CH63_RS16155	COG3118	belongs to the thioredoxin family
CH63_RS16160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH63_RS16165	COG2814	Major facilitator Superfamily
CH63_RS16170	COG1566	PFAM secretion protein HlyD family protein
CH63_RS16175	COG1846	Transcriptional regulator
CH63_RS16185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH63_RS16190	COG2814	Major facilitator Superfamily
CH63_RS16230	COG0765	amino acid transport
CH63_RS16240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH63_RS16265	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH63_RS16275	COG1960	acyl-CoA dehydrogenase activity
CH63_RS16285	COG0121	glutamine amidotransferase
CH63_RS16290	COG3034	peptidoglycan biosynthetic process
CH63_RS16300	COG1805	sodium ion transport
CH63_RS16305	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH63_RS16325	COG1477	protein flavinylation
CH63_RS16345	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH63_RS16415	COG2226	methyltransferase
CH63_RS16465	COG1940	carbohydrate kinase activity
CH63_RS16470	COG0419	ATPase involved in DNA repair
CH63_RS16475	COG0420	3'-5' exonuclease activity
CH63_RS16485	COG0745	RESPONSE REGULATOR receiver
CH63_RS16490	COG5002	protein histidine kinase activity
CH63_RS16510	COG0366	Alpha amylase catalytic
CH63_RS16535	COG0450	alkyl hydroperoxide reductase
CH63_RS16555	COG1862	Preprotein translocase
CH63_RS16560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH63_RS16565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH63_RS16590	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH63_RS16590	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH63_RS16605	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH63_RS16610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH63_RS16630	COG0142	geranyltranstransferase activity
CH63_RS16650	COG0693	protein deglycase activity
CH63_RS16655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH63_RS16665	COG2814	Major facilitator Superfamily
CH63_RS16675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH63_RS16680	COG1845	cytochrome c oxidase, subunit III
CH63_RS16685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH63_RS16690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH63_RS16700	COG2223	nitrite transmembrane transporter activity
CH63_RS16705	COG3056	Lipoprotein
CH63_RS16710	COG0271	Belongs to the BolA IbaG family
CH63_RS16735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH63_RS16740	COG0776	regulation of translation
CH63_RS16745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH63_RS16750	COG1555	photosystem II stabilization
CH63_RS16755	COG0824	Thioesterase
CH63_RS16765	COG4533	DNA binding
CH63_RS16780	COG1522	sequence-specific DNA binding
CH63_RS16785	COG1132	(ABC) transporter
CH63_RS16790	COG1132	(ABC) transporter
CH63_RS16795	COG0347	Belongs to the P(II) protein family
CH63_RS16800	COG0004	ammonium transporteR
CH63_RS16805	COG1946	Acyl-CoA thioesterase
CH63_RS16810	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH63_RS16815	COG3695	enzyme binding
CH63_RS16835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH63_RS16845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH63_RS16850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_RS16855	COG1309	transcriptional regulator
CH63_RS16860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH63_RS16865	COG3264	Mechanosensitive ion channel
CH63_RS16865	COG1196	nuclear chromosome segregation
CH63_RS16890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH63_RS16940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_RS16980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_RS17000	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH63_RS17005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_RS17010	COG4651	solute:proton antiporter activity
CH63_RS17010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH63_RS17015	COG2223	nitrite transmembrane transporter activity
CH63_RS17020	COG0737	Belongs to the 5'-nucleotidase family
CH63_RS17030	COG0737	Belongs to the 5'-nucleotidase family
CH63_RS17045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH63_RS17050	COG3735	TraB family
CH63_RS17055	COG2217	Heavy metal translocating P-type atpase
CH63_RS17060	COG0789	Transcriptional regulator
CH63_RS17065	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH63_RS17070	COG0330	HflC and HflK could
CH63_RS17075	COG3118	belongs to the thioredoxin family
CH63_RS17080	COG0300	oxidoreductase activity
CH63_RS17085	COG2755	lipolytic protein G-D-S-L family
CH63_RS17090	COG4181	ATPase activity
CH63_RS17095	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH63_RS17100	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH63_RS17105	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH63_RS17115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH63_RS17135	COG2501	S4 domain
CH63_RS17185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH63_RS17190	COG4589	Belongs to the CDS family
CH63_RS17200	COG2267	carboxylic ester hydrolase activity
CH63_RS17205	COG2453	phosphatase
CH63_RS17205	COG0671	phosphoesterase, PA-phosphatase related
CH63_RS17240	COG0667	Aldo Keto reductase
CH63_RS17245	COG0656	L-ascorbic acid biosynthetic process
CH63_RS17265	COG1472	Belongs to the glycosyl hydrolase 3 family
CH63_RS17280	COG3328	transposase activity
CH63_RS17285	COG2850	peptidyl-arginine hydroxylation
CH63_RS17335	COG3423	Transcriptional regulator
CH63_RS17340	COG4953	penicillin-binding protein 1C
CH63_RS17355	COG2373	Large extracellular alpha-helical protein
CH63_RS17375	COG3962	Belongs to the TPP enzyme family
CH63_RS17390	COG1129	ABC transporter
CH63_RS17395	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS17400	COG0673	inositol 2-dehydrogenase activity
CH63_RS17405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_RS17415	COG3718	enzyme involved in inositol metabolism
CH63_RS17425	COG5265	(ABC) transporter
CH63_RS17450	COG2197	response regulator
CH63_RS17455	COG1278	Cold shock
CH63_RS17465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH63_RS17475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH63_RS17495	COG1686	Belongs to the peptidase S11 family
CH63_RS17500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH63_RS17505	COG0772	Belongs to the SEDS family
CH63_RS17510	COG0768	penicillin binding
CH63_RS17520	COG0799	negative regulation of ribosome biogenesis
CH63_RS17530	COG1466	dna polymerase III delta subunit
CH63_RS17545	COG2888	peptidyl-tyrosine sulfation
CH63_RS17550	COG1126	abc transporter atp-binding protein
CH63_RS17555	COG0765	amino acid transport
CH63_RS17560	COG0765	amino acid transport
CH63_RS17570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH63_RS17575	COG4535	Mg2 and Co2 transporter CorC
CH63_RS17585	COG1702	phosphate starvation-inducible protein PhoH
CH63_RS17590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH63_RS17595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH63_RS17635	COG0367	asparagine synthase
CH63_RS17640	COG0647	UMP catabolic process
CH63_RS17645	COG1940	carbohydrate kinase activity
CH63_RS17645	COG1846	Transcriptional regulator
CH63_RS17650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH63_RS17660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_RS17660	COG2190	(PTS) system
CH63_RS17660	COG1263	PTS System
CH63_RS17685	COG0735	belongs to the Fur family
CH63_RS17705	COG0596	Alpha beta hydrolase
CH63_RS17715	COG0582	viral genome integration into host DNA
CH63_RS17720	COG2963	transposase activity
CH63_RS17725	COG0582	viral genome integration into host DNA
CH63_RS17745	COG2113	Glycine betaine
CH63_RS17750	COG4176	ABC-type proline glycine betaine transport system permease component
CH63_RS17755	COG4175	Glycine betaine
CH63_RS17760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH63_RS17800	COG1278	Cold shock
CH63_RS17805	COG0747	negative chemotaxis
CH63_RS17815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH63_RS17820	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH63_RS17825	COG1124	(ABC) transporter
CH63_RS17830	COG0831	urea catabolic process
CH63_RS17855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH63_RS17865	COG4413	Urea transporter
CH63_RS17870	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH63_RS17885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH63_RS17895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH63_RS17905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH63_RS17910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH63_RS17915	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH63_RS17920	COG1917	Cupin 2, conserved barrel domain protein
CH63_RS17920	COG2169	Transcriptional regulator
CH63_RS17940	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH63_RS17945	COG0033	Phosphoglucomutase
CH63_RS17965	COG0745	RESPONSE REGULATOR receiver
CH63_RS17970	COG2205	protein histidine kinase activity
CH63_RS18005	COG3272	Protein of unknown function (DUF1722)
CH63_RS18015	COG5212	phosphodiesterase
CH63_RS18020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH63_RS18030	COG1984	allophanate hydrolase subunit 2
CH63_RS18080	COG0513	Belongs to the DEAD box helicase family
CH63_RS18090	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH63_RS18105	COG3026	antisigma factor binding
CH63_RS18110	COG3086	response to oxidative stress
CH63_RS18145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH63_RS18165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH63_RS18170	COG1737	Transcriptional regulator
CH63_RS18180	COG0560	Phosphoserine phosphatase
CH63_RS18220	COG2205	protein histidine kinase activity
CH63_RS18225	COG3170	Tfp pilus assembly protein FimV
CH63_RS18230	COG2204	response regulator
CH63_RS18235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH63_RS18235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH63_RS18240	COG0347	Belongs to the P(II) protein family
CH63_RS18245	COG2188	Transcriptional regulator
CH63_RS18250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_RS18250	COG1017	nitric oxide dioxygenase activity
CH63_RS18270	COG2814	Major facilitator Superfamily
CH63_RS18275	COG3711	transcriptional antiterminator
CH63_RS18280	COG3683	transport system, periplasmic component
CH63_RS18285	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH63_RS18310	COG1104	cysteine desulfurase activity
CH63_RS18315	COG0822	iron-sulfur transferase activity
CH63_RS18330	COG0443	Heat shock 70 kDa protein
CH63_RS18335	COG0633	Ferredoxin
CH63_RS18340	COG2975	iron-sulfur cluster assembly
CH63_RS18360	COG3468	outer membrane autotransporter barrel domain protein
CH63_RS18410	COG2976	Protein conserved in bacteria
CH63_RS18415	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH63_RS18430	COG1645	bacterial-type flagellum-dependent swarming motility
CH63_RS18440	COG0517	IMP dehydrogenase activity
CH63_RS18440	COG0516	GMP reductase activity
CH63_RS18495	COG3328	transposase activity
CH63_RS18505	COG0513	Belongs to the DEAD box helicase family
CH63_RS18525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH63_RS18535	COG1686	Belongs to the peptidase S11 family
CH63_RS18540	COG0277	FAD linked oxidase domain protein
CH63_RS18560	COG2261	transglycosylase associated protein
CH63_RS18570	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH63_RS18585	COG4807	Protein conserved in bacteria
CH63_RS18605	COG1122	ATPase activity
CH63_RS18625	COG2897	thiosulfate sulfurtransferase activity
CH63_RS18630	COG1732	Glycine betaine
CH63_RS18635	COG1732	Glycine betaine
CH63_RS18640	COG1174	glycine betaine transport
CH63_RS18645	COG1125	glycine betaine transport
CH63_RS18650	COG1174	glycine betaine transport
CH63_RS18655	COG0531	amino acid
CH63_RS18660	COG1982	Orn Lys Arg decarboxylase major
CH63_RS18670	COG0697	spore germination
CH63_RS18680	COG1199	ATP-dependent helicase activity
CH63_RS18695	COG0814	amino acid
CH63_RS18710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_RS18740	COG0784	Response regulator, receiver
CH63_RS18740	COG2205	protein histidine kinase activity
CH63_RS18750	COG2198	Histidine kinase
CH63_RS18750	COG0642	Histidine kinase
CH63_RS18755	COG2198	Histidine kinase
CH63_RS18755	COG0642	Histidine kinase
CH63_RS18760	COG2223	nitrite transmembrane transporter activity
CH63_RS18790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH63_RS18835	COG3395	kinase activity
CH63_RS18845	COG1349	DNA-binding transcription factor activity
CH63_RS18850	COG3622	Belongs to the hyi family
CH63_RS18910	COG3299	homolog of phage Mu protein gp47
CH63_RS18930	COG1737	Transcriptional regulator
CH63_RS18935	COG2723	6-phospho-beta-galactosidase activity
CH63_RS18955	COG3157	Type VI secretion system effector, Hcp
CH63_RS18970	COG3083	sulfuric ester hydrolase activity
CH63_RS18975	COG3082	Protein of unknown function (DUF1414)
CH63_RS19000	COG1061	Type III restriction enzyme res subunit
CH63_RS19005	COG1187	pseudouridine synthase activity
CH63_RS19010	COG2814	Major facilitator Superfamily
CH63_RS19020	COG4172	Belongs to the ABC transporter superfamily
CH63_RS19025	COG4239	(ABC) transporter, permease
CH63_RS19030	COG4174	ABC transporter (Permease)
CH63_RS19035	COG4166	transmembrane transport
CH63_RS19040	COG2200	EAL domain
CH63_RS19045	COG0791	NLP P60 protein
CH63_RS19050	COG0671	phosphoesterase, PA-phosphatase related
CH63_RS19055	COG0523	cobalamin synthesis protein
CH63_RS19065	COG2186	Transcriptional regulator
CH63_RS19070	COG0246	Mannitol dehydrogenase
CH63_RS19095	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS19130	COG1129	ABC transporter
CH63_RS19140	COG0494	nUDIX hydrolase
CH63_RS19150	COG1105	Belongs to the carbohydrate kinase PfkB family
CH63_RS19160	COG3710	Transcriptional regulator
CH63_RS19175	COG3121	Chaperone
CH63_RS19180	COG3188	usher protein
CH63_RS19190	COG2855	membrane
CH63_RS19195	COG0583	DNA-binding transcription factor activity
CH63_RS19210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_RS19220	COG4771	TonB-dependent receptor
CH63_RS19225	COG0625	glutathione transferase activity
CH63_RS19250	COG2011	ABC-type metal ion transport system permease component
CH63_RS19255	COG1686	Belongs to the peptidase S11 family
CH63_RS19270	COG1349	DNA-binding transcription factor activity
CH63_RS19280	COG0671	phosphoesterase, PA-phosphatase related
CH63_RS19315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH63_RS19320	COG3842	ATPase activity
CH63_RS19325	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH63_RS19330	COG1177	transmembrane transport
CH63_RS19345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_RS19375	COG1120	ATPase activity
CH63_RS19400	COG4160	amino acid transport
CH63_RS19405	COG4215	(ABC) transporter
CH63_RS19410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_RS19415	COG1126	abc transporter atp-binding protein
CH63_RS19420	COG1605	Chorismate mutase
CH63_RS19430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_RS19435	COG0702	epimerase
CH63_RS19440	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH63_RS19445	COG0028	Belongs to the TPP enzyme family
CH63_RS19450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH63_RS19460	COG2431	L-lysine efflux transmembrane transporter activity
CH63_RS19465	COG3593	DNA synthesis involved in DNA repair
CH63_RS19470	COG2990	Protein conserved in bacteria
CH63_RS19475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH63_RS19485	COG1278	Cold shock
CH63_RS19495	COG0542	response to heat
CH63_RS19505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH63_RS19515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH63_RS19530	COG0492	ferredoxin-NADP+ reductase activity
CH63_RS19540	COG1674	ftsk spoiiie
CH63_RS19540	COG3107	peptidoglycan biosynthetic process
CH63_RS19550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH63_RS19590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH63_RS19600	COG1882	Formate acetyltransferase
CH63_RS19605	COG2116	formate transmembrane transporter activity
CH63_RS19610	COG1944	ATP diphosphatase activity
CH63_RS19615	COG0252	asparaginase activity
CH63_RS19620	COG5295	Hep Hag repeat protein
CH63_RS19620	COG5295	Hep Hag repeat protein
CH63_RS19645	COG0539	negative regulation of cytoplasmic translation
CH63_RS19675	COG5383	Protein conserved in bacteria
CH63_RS19680	COG1278	Cold shock
CH63_RS19695	COG3173	Aminoglycoside phosphotransferase
CH63_RS19705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH63_RS19735	COG2989	Protein conserved in bacteria
CH63_RS19740	COG3108	Peptidase M15
CH63_RS19745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH63_RS19750	COG1448	Aminotransferase
CH63_RS19770	COG0308	aminopeptidase N
CH63_RS19785	COG0633	Ferredoxin
CH63_RS19785	COG3217	Mosc domain protein beta barrel domain protein
CH63_RS19795	COG0488	(ABC) transporter
CH63_RS19800	COG2995	paraquat-inducible protein a
CH63_RS19805	COG3008	intermembrane lipid transfer
CH63_RS19805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH63_RS19810	COG3009	Protein conserved in bacteria
CH63_RS19820	COG3130	regulation of translation
CH63_RS19835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_RS19850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_RS19865	COG1067	ATP-dependent peptidase activity
CH63_RS19895	COG3070	regulator of competence-specific genes
CH63_RS19900	COG1289	transmembrane transporter activity
CH63_RS19905	COG3304	Inner membrane component domain
CH63_RS19910	COG0210	DNA helicase
CH63_RS19925	COG1832	CoA-binding protein
CH63_RS19945	COG2920	part of a sulfur-relay system
CH63_RS19980	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS19990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH63_RS19995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH63_RS20000	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS20005	COG3425	synthase
CH63_RS20015	COG1024	Enoyl-CoA hydratase
CH63_RS20020	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS20030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH63_RS20035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH63_RS20170	COG0488	(ABC) transporter
CH63_RS20180	COG3328	transposase activity
CH63_RS20190	COG0303	'Molybdopterin
CH63_RS20200	COG1136	(ABC) transporter
CH63_RS20235	COG0583	DNA-binding transcription factor activity
CH63_RS20240	COG0477	Major facilitator Superfamily
CH63_RS20250	COG2311	Membrane
CH63_RS20265	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH63_RS20270	COG2949	membrane
CH63_RS20285	COG1346	cytolysis
CH63_RS20295	COG2814	Major facilitator Superfamily
CH63_RS20330	COG0489	protein tyrosine kinase activity
CH63_RS20345	COG2982	Protein involved in outer membrane biogenesis
CH63_RS20350	COG1253	flavin adenine dinucleotide binding
CH63_RS20355	COG4114	ferric iron reductase
CH63_RS20360	COG0076	glutamate decarboxylase activity
CH63_RS20365	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH63_RS20380	COG1120	ATPase activity
CH63_RS20385	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_RS20390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH63_RS20395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH63_RS20410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH63_RS20415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH63_RS20425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH63_RS20425	COG0140	phosphoribosyl-ATP diphosphatase activity
CH63_RS20445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH63_RS20445	COG0131	Imidazoleglycerol-phosphate dehydratase
CH63_RS20455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH63_RS20465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_RS20475	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS20480	COG1129	ABC transporter
CH63_RS20485	COG1129	ABC transporter
CH63_RS20490	COG0371	Dehydrogenase
CH63_RS20500	COG0531	amino acid
CH63_RS20505	COG2925	Exonuclease
CH63_RS20520	COG3328	transposase activity
CH63_RS20525	COG1388	LysM domain
CH63_RS20525	COG1470	cell adhesion involved in biofilm formation
CH63_RS20530	COG2271	Major facilitator Superfamily
CH63_RS20535	COG3011	Protein conserved in bacteria
CH63_RS20540	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS20550	COG4948	Mandelate Racemase Muconate Lactonizing
CH63_RS20565	COG0534	Mate efflux family protein
CH63_RS20585	COG3122	Protein conserved in bacteria
CH63_RS20610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH63_RS20630	COG2223	nitrite transmembrane transporter activity
CH63_RS20635	COG3328	transposase activity
CH63_RS20685	COG1132	(ABC) transporter
CH63_RS20695	COG2207	Transcriptional regulator
CH63_RS20730	COG1113	amino acid transport
CH63_RS20755	COG1496	oxidoreductase activity
CH63_RS20760	COG2226	methyltransferase
CH63_RS20790	COG3716	PTS system mannose fructose sorbose family IID component
CH63_RS20795	COG3715	PTS system
CH63_RS20800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH63_RS20800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH63_RS20805	COG1253	flavin adenine dinucleotide binding
CH63_RS20810	COG1846	Transcriptional regulator
CH63_RS20825	COG1012	belongs to the aldehyde dehydrogenase family
CH63_RS20830	COG3384	dioxygenase
CH63_RS20840	COG3971	2-oxopent-4-enoate hydratase activity
CH63_RS20855	COG2368	4-hydroxyphenylacetate
CH63_RS20860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH63_RS20865	COG1760	l-serine dehydratase
CH63_RS20890	COG0513	Belongs to the DEAD box helicase family
CH63_RS20895	COG3141	response to X-ray
CH63_RS20910	COG1770	oligopeptidase
CH63_RS20925	COG1528	Iron-storage protein
CH63_RS20930	COG2372	response to copper ion
CH63_RS20960	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH63_RS20965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH63_RS20990	COG3418	PFAM FlgN family protein
CH63_RS20995	COG2747	anti-sigma28 factor FlgM
CH63_RS21005	COG1815	bacterial-type flagellum-dependent cell motility
CH63_RS21010	COG1558	bacterial-type flagellum-dependent cell motility
CH63_RS21050	COG1256	bacterial-type flagellum assembly
CH63_RS21060	COG2390	Transcriptional regulator
CH63_RS21065	COG1028	Short-chain dehydrogenase reductase Sdr
CH63_RS21065	COG3347	Dehydrogenase
CH63_RS21070	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH63_RS21080	COG1129	ABC transporter
CH63_RS21090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH63_RS21110	COG1987	bacterial-type flagellum assembly
CH63_RS21135	COG1580	Controls the rotational direction of flagella during chemotaxis
CH63_RS21150	COG1157	protein secretion by the type III secretion system
CH63_RS21170	COG1677	Flagellar hook-basal body complex protein FliE
CH63_RS21185	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH63_RS21190	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH63_RS21230	COG1191	sigma factor activity
CH63_RS21245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH63_RS21250	COG0765	amino acid transport
CH63_RS21255	COG1126	abc transporter atp-binding protein
CH63_RS21270	COG0506	proline dehydrogenase activity
CH63_RS21270	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH63_RS21270	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH63_RS21285	COG0672	)-iron permease
CH63_RS21290	COG2822	iron ion transport
CH63_RS21310	COG1113	amino acid transport
CH63_RS21330	COG3136	membrane protein required for alginate biosynthesis
CH63_RS21340	COG2197	response regulator
CH63_RS21480	COG2188	Transcriptional regulator
CH63_RS21490	COG0673	inositol 2-dehydrogenase activity
CH63_RS21500	COG1175	transmembrane transport
CH63_RS21505	COG0395	ABC-type sugar transport system, permease component
CH63_RS21510	COG3842	ATPase activity
CH63_RS21565	COG0402	S-adenosylhomocysteine deaminase activity
CH63_RS21580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH63_RS21585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH63_RS21590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH63_RS21635	COG3328	transposase activity
CH63_RS21660	COG0500	methyltransferase
CH63_RS21700	COG5002	protein histidine kinase activity
CH63_RS21755	COG0012	GTP binding
CH63_RS21775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH63_RS21805	COG2890	protein-(glutamine-N5) methyltransferase activity
CH63_RS21825	COG0659	secondary active sulfate transmembrane transporter activity
CH63_RS21850	COG3833	ABC-type maltose transport systems, permease component
CH63_RS21855	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH63_RS21865	COG0584	glycerophosphoryl diester phosphodiesterase
CH63_RS21870	COG1940	carbohydrate kinase activity
CH63_RS21885	COG3381	protein complex oligomerization
CH63_RS21900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH63_RS21915	COG0728	peptidoglycan biosynthetic process
CH63_RS21935	COG3102	Protein conserved in bacteria
CH63_RS21955	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH63_RS21960	COG1801	Protein of unknown function DUF72
CH63_RS21970	COG0494	nUDIX hydrolase