locus-tag	class	description
YPDSF_RS00010	COG0592	DNA-directed DNA polymerase activity
YPDSF_RS00025	COG0187	DNA topoisomerase II activity
YPDSF_RS00030	COG0561	phosphatase activity
YPDSF_RS00035	COG2801	Transposase and inactivated derivatives
YPDSF_RS00045	COG2423	ornithine cyclodeaminase activity
YPDSF_RS00050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPDSF_RS00055	COG0823	Involved in the tonB-independent uptake of proteins
YPDSF_RS00060	COG0823	Involved in the tonB-independent uptake of proteins
YPDSF_RS00065	COG5645	(Lipo)protein
YPDSF_RS00085	COG3977	Valine--pyruvate aminotransferase
YPDSF_RS00095	COG0366	Alpha amylase catalytic
YPDSF_RS00110	COG2885	chlorophyll binding
YPDSF_RS00120	COG2818	Glycosylase
YPDSF_RS00140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_RS00140	COG2213	PTS system mannitol-specific
YPDSF_RS00150	COG3722	fumarate hydratase activity
YPDSF_RS00175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPDSF_RS00185	COG0243	molybdopterin cofactor binding
YPDSF_RS00185	COG3383	formate dehydrogenase (NAD+) activity
YPDSF_RS00190	COG3383	formate dehydrogenase (NAD+) activity
YPDSF_RS00190	COG0243	molybdopterin cofactor binding
YPDSF_RS00195	COG0437	4 iron, 4 sulfur cluster binding
YPDSF_RS00200	COG2864	formate dehydrogenase
YPDSF_RS00215	COG3276	selenocysteine insertion sequence binding
YPDSF_RS00230	COG3328	transposase activity
YPDSF_RS00260	COG2801	Transposase and inactivated derivatives
YPDSF_RS00270	COG1349	DNA-binding transcription factor activity
YPDSF_RS00290	COG0058	SHG alpha-glucan phosphorylase activity
YPDSF_RS00295	COG1640	4-alpha-glucanotransferase
YPDSF_RS00330	COG1918	ferrous iron import across plasma membrane
YPDSF_RS00340	COG2183	response to ionizing radiation
YPDSF_RS00345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPDSF_RS00370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPDSF_RS00375	COG1011	Hydrolase
YPDSF_RS00390	COG0494	nUDIX hydrolase
YPDSF_RS00395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPDSF_RS00425	COG4796	Type ii and iii secretion system protein
YPDSF_RS00450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPDSF_RS00455	COG0546	phosphoglycolate phosphatase activity
YPDSF_RS00460	COG0180	Tryptophanyl-tRNA synthetase
YPDSF_RS00480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPDSF_RS00485	COG0402	S-adenosylhomocysteine deaminase activity
YPDSF_RS00510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPDSF_RS00515	COG0433	COG0433 Predicted ATPase
YPDSF_RS00530	COG1289	transmembrane transporter activity
YPDSF_RS00540	COG1765	OsmC-like protein
YPDSF_RS00550	COG3954	Phosphoribulokinase
YPDSF_RS00560	COG0429	hydrolase of the alpha beta-hydrolase fold
YPDSF_RS00570	COG4521	taurine ABC transporter
YPDSF_RS00580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPDSF_RS00585	COG2175	clavaminate synthase activity
YPDSF_RS00595	COG1216	Glycosyl transferase, family 2
YPDSF_RS00600	COG0488	(ABC) transporter
YPDSF_RS00615	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPDSF_RS00620	COG1047	Peptidyl-prolyl cis-trans
YPDSF_RS00630	COG0545	Peptidyl-prolyl cis-trans isomerase
YPDSF_RS00635	COG2964	Protein conserved in bacteria
YPDSF_RS00660	COG0049	tRNA binding
YPDSF_RS00690	COG0051	transcription antitermination factor activity, RNA binding
YPDSF_RS00705	COG0089	rRNA binding
YPDSF_RS00715	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPDSF_RS00725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPDSF_RS00730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPDSF_RS00740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPDSF_RS00745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPDSF_RS00785	COG1841	ribosomal large subunit assembly
YPDSF_RS00795	COG0201	protein transport
YPDSF_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPDSF_RS00815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPDSF_RS00830	COG0789	Transcriptional regulator
YPDSF_RS00835	COG3036	rescue of stalled ribosome
YPDSF_RS00865	COG0758	DNA mediated transformation
YPDSF_RS00875	COG0551	DNA topoisomerase type I activity
YPDSF_RS00890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPDSF_RS00945	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPDSF_RS00950	COG2224	Isocitrate lyase
YPDSF_RS00960	COG1414	Transcriptional regulator
YPDSF_RS00980	COG0527	aspartate kinase activity
YPDSF_RS00995	COG3833	ABC-type maltose transport systems, permease component
YPDSF_RS01000	COG1175	transmembrane transport
YPDSF_RS01060	COG2801	Transposase and inactivated derivatives
YPDSF_RS01135	COG3501	Rhs element vgr protein
YPDSF_RS01180	COG3501	Rhs element vgr protein
YPDSF_RS01190	COG3209	COG3209 Rhs family protein
YPDSF_RS01205	COG0673	inositol 2-dehydrogenase activity
YPDSF_RS01210	COG1917	Cupin 2, conserved barrel domain protein
YPDSF_RS01210	COG2207	Transcriptional regulator
YPDSF_RS01215	COG1869	D-ribose catabolic process
YPDSF_RS01220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_RS01225	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPDSF_RS01230	COG0431	NADPH-dependent FMN reductase
YPDSF_RS01235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPDSF_RS01245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPDSF_RS01255	COG3077	Addiction module antitoxin, RelB DinJ family
YPDSF_RS01260	COG2252	PERMEase
YPDSF_RS01265	COG0025	NhaP-type Na H and K H
YPDSF_RS01275	COG1560	Kdo2-lipid A biosynthetic process
YPDSF_RS01285	COG1129	ABC transporter
YPDSF_RS01290	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS01300	COG1069	ribulokinase activity
YPDSF_RS01310	COG0625	glutathione transferase activity
YPDSF_RS01335	COG1278	Cold shock
YPDSF_RS01340	COG1278	Cold shock
YPDSF_RS01350	COG3133	Outer membrane lipoprotein
YPDSF_RS01355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPDSF_RS01365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPDSF_RS01390	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPDSF_RS01395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPDSF_RS01405	COG4145	pantothenate transmembrane transporter activity
YPDSF_RS01410	COG3924	membrane
YPDSF_RS01415	COG0439	Biotin carboxylase
YPDSF_RS01420	COG0511	ligase activity, forming carbon-carbon bonds
YPDSF_RS01435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YPDSF_RS01440	COG0604	alcohol dehydrogenase
YPDSF_RS01445	COG2200	EAL domain
YPDSF_RS01445	COG2199	diguanylate cyclase activity
YPDSF_RS01450	COG1077	Cell shape determining protein MreB Mrl
YPDSF_RS01455	COG1792	Involved in formation and maintenance of cell shape
YPDSF_RS01460	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPDSF_RS01465	COG0424	maF-like protein
YPDSF_RS01470	COG1530	ribonuclease E activity
YPDSF_RS01475	COG3164	Protein of unknown function
YPDSF_RS01480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPDSF_RS01485	COG0312	modulator of DNA gyrase
YPDSF_RS01540	COG0583	DNA-binding transcription factor activity
YPDSF_RS01560	COG1012	belongs to the aldehyde dehydrogenase family
YPDSF_RS01575	COG2732	(Barnase) inhibitor
YPDSF_RS01585	COG0312	modulator of DNA gyrase
YPDSF_RS01595	COG3783	Cytochrome b(562)
YPDSF_RS01600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPDSF_RS01605	COG0366	Alpha amylase catalytic
YPDSF_RS01610	COG1263	PTS System
YPDSF_RS01610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_RS01615	COG1609	Transcriptional regulator
YPDSF_RS01640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_RS01660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPDSF_RS01665	COG1137	ATPase activity
YPDSF_RS01670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPDSF_RS01675	COG3117	lipopolysaccharide transmembrane transporter activity
YPDSF_RS01680	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPDSF_RS01685	COG0517	IMP dehydrogenase activity
YPDSF_RS01685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPDSF_RS01690	COG0530	calcium, potassium:sodium antiporter activity
YPDSF_RS01695	COG1127	ABC transporter
YPDSF_RS01700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPDSF_RS01705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPDSF_RS01710	COG2854	intermembrane phospholipid transfer
YPDSF_RS01715	COG3113	response to antibiotic
YPDSF_RS01720	COG5007	Belongs to the BolA IbaG family
YPDSF_RS01730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPDSF_RS01740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPDSF_RS01745	COG3105	Protein conserved in bacteria
YPDSF_RS01750	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPDSF_RS01770	COG0625	glutathione transferase activity
YPDSF_RS01775	COG2969	positive regulation of protein catabolic process
YPDSF_RS01785	COG0493	'glutamate synthase
YPDSF_RS01790	COG0070	glutamate synthase
YPDSF_RS01790	COG0067	glutamate synthase
YPDSF_RS01790	COG0069	glutamate synthase activity
YPDSF_RS01795	COG1242	4 iron, 4 sulfur cluster binding
YPDSF_RS01805	COG0784	Response regulator, receiver
YPDSF_RS01805	COG2198	Histidine kinase
YPDSF_RS01805	COG5002	protein histidine kinase activity
YPDSF_RS01825	COG2823	Periplasmic or secreted lipoprotein
YPDSF_RS01845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPDSF_RS01850	COG1741	Belongs to the pirin family
YPDSF_RS01855	COG0583	DNA-binding transcription factor activity
YPDSF_RS01860	COG0435	Glutathione S-transferase
YPDSF_RS01865	COG2259	Doxx family
YPDSF_RS01875	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPDSF_RS01880	COG4575	ribosome binding
YPDSF_RS01900	COG0586	Pfam SNARE associated Golgi protein
YPDSF_RS01935	COG2721	sulfolactate sulfo-lyase activity
YPDSF_RS01955	COG0673	inositol 2-dehydrogenase activity
YPDSF_RS01960	COG1451	nucleotide metabolic process
YPDSF_RS01975	COG1902	pentaerythritol trinitrate reductase activity
YPDSF_RS01975	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPDSF_RS01980	COG3247	response to pH
YPDSF_RS02015	COG4245	von Willebrand factor, type A
YPDSF_RS02020	COG2831	hemolysin activation secretion protein
YPDSF_RS02025	COG3210	domain, Protein
YPDSF_RS02050	COG3210	domain, Protein
YPDSF_RS02055	COG3210	domain, Protein
YPDSF_RS02075	COG3842	ATPase activity
YPDSF_RS02080	COG3459	Glycosyltransferase 36 associated
YPDSF_RS02085	COG1609	Transcriptional regulator
YPDSF_RS02090	COG2182	Extracellular solute-binding protein
YPDSF_RS02100	COG0395	ABC-type sugar transport system, permease component
YPDSF_RS02120	COG1289	transmembrane transporter activity
YPDSF_RS02145	COG0436	Aminotransferase
YPDSF_RS02165	COG0251	oxidation-reduction process
YPDSF_RS02260	COG0358	DNA primase activity
YPDSF_RS02265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YPDSF_RS02280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPDSF_RS02295	COG4991	sh3 domain protein
YPDSF_RS02300	COG3025	triphosphatase activity
YPDSF_RS02315	COG0531	amino acid
YPDSF_RS02335	COG3384	dioxygenase
YPDSF_RS02340	COG0754	glutathionylspermidine amidase activity
YPDSF_RS02355	COG1538	Outer membrane efflux protein
YPDSF_RS02360	COG0494	nUDIX hydrolase
YPDSF_RS02365	COG3151	Protein conserved in bacteria
YPDSF_RS02370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPDSF_RS02375	COG3150	esterase
YPDSF_RS02385	COG0583	DNA-binding transcription factor activity
YPDSF_RS02390	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPDSF_RS02395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPDSF_RS02405	COG2132	Multicopper oxidase
YPDSF_RS02415	COG0656	L-ascorbic acid biosynthetic process
YPDSF_RS02425	COG1979	alcohol dehydrogenase
YPDSF_RS02430	COG2207	Transcriptional regulator
YPDSF_RS02435	COG0586	Pfam SNARE associated Golgi protein
YPDSF_RS02440	COG0626	cystathionine gamma-synthase activity
YPDSF_RS02445	COG0811	peptide transport
YPDSF_RS02450	COG0848	biopolymer transport protein
YPDSF_RS02500	COG4964	Belongs to the GSP D family
YPDSF_RS02505	COG4964	Belongs to the GSP D family
YPDSF_RS02540	COG4592	Periplasmic binding protein
YPDSF_RS02560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPDSF_RS02565	COG1684	flagellar biosynthetic protein fliR
YPDSF_RS02570	COG1987	bacterial-type flagellum assembly
YPDSF_RS02595	COG1677	Flagellar hook-basal body complex protein FliE
YPDSF_RS02635	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPDSF_RS02640	COG1815	bacterial-type flagellum-dependent cell motility
YPDSF_RS02645	COG1558	bacterial-type flagellum-dependent cell motility
YPDSF_RS02650	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPDSF_RS02655	COG1749	Flagellar hook protein flgE
YPDSF_RS02660	COG4787	bacterial-type flagellum-dependent cell motility
YPDSF_RS02665	COG4786	Flagellar basal body rod
YPDSF_RS02675	COG1706	bacterial-type flagellum-dependent cell motility
YPDSF_RS02685	COG1256	bacterial-type flagellum assembly
YPDSF_RS02705	COG3710	Transcriptional regulator
YPDSF_RS02725	COG2801	Transposase and inactivated derivatives
YPDSF_RS02730	COG2211	Major facilitator Superfamily
YPDSF_RS02780	COG2771	luxR family
YPDSF_RS02785	COG3916	Acyl-homoserine-lactone synthase
YPDSF_RS02890	COG1982	Orn Lys Arg decarboxylase major
YPDSF_RS02895	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_RS02900	COG1129	ABC transporter
YPDSF_RS02905	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS02910	COG4774	siderophore transport
YPDSF_RS02930	COG1194	a g-specific adenine glycosylase
YPDSF_RS02940	COG3171	Protein conserved in bacteria
YPDSF_RS02960	COG3064	Membrane
YPDSF_RS02960	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPDSF_RS02960	COG1073	alpha beta
YPDSF_RS02965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPDSF_RS02970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPDSF_RS02980	COG0762	integral membrane protein
YPDSF_RS02985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPDSF_RS02990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPDSF_RS02995	COG2805	Type II/IV secretion system protein
YPDSF_RS03005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPDSF_RS03020	COG0189	ligase activity
YPDSF_RS03025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPDSF_RS03030	COG2356	endonuclease I
YPDSF_RS03045	COG1166	arginine decarboxylase activity
YPDSF_RS03055	COG0501	Belongs to the peptidase M48B family
YPDSF_RS03060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPDSF_RS03080	COG0191	fructose-bisphosphate aldolase activity
YPDSF_RS03115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPDSF_RS03130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPDSF_RS03145	COG0006	proline dipeptidase activity
YPDSF_RS03150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPDSF_RS03155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPDSF_RS03185	COG5295	Hep Hag repeat protein
YPDSF_RS03195	COG1272	protein, Hemolysin III
YPDSF_RS03220	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS03225	COG2205	protein histidine kinase activity
YPDSF_RS03230	COG4452	Inner membrane protein CreD
YPDSF_RS03235	COG0716	FMN binding
YPDSF_RS03240	COG4974	Belongs to the 'phage' integrase family
YPDSF_RS03245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPDSF_RS03250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPDSF_RS03270	COG0582	viral genome integration into host DNA
YPDSF_RS03300	COG2944	sequence-specific DNA binding
YPDSF_RS03395	COG1695	Transcriptional regulator
YPDSF_RS03400	COG0791	NLP P60 protein
YPDSF_RS03410	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_RS03415	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS03420	COG1129	ABC transporter
YPDSF_RS03430	COG2182	Extracellular solute-binding protein
YPDSF_RS03440	COG3833	ABC-type maltose transport systems, permease component
YPDSF_RS03445	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPDSF_RS03455	COG1263	PTS System
YPDSF_RS03455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_RS03475	COG2271	Major facilitator Superfamily
YPDSF_RS03505	COG3119	arylsulfatase activity
YPDSF_RS03510	COG0641	radical SAM
YPDSF_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS03530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_RS03535	COG3716	PTS system mannose fructose sorbose family IID component
YPDSF_RS03540	COG3715	PTS system
YPDSF_RS03545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_RS03550	COG2222	sugar isomerase
YPDSF_RS03560	COG1349	DNA-binding transcription factor activity
YPDSF_RS03565	COG3119	arylsulfatase activity
YPDSF_RS03610	COG0288	reversible hydration of carbon dioxide
YPDSF_RS03630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPDSF_RS03695	COG3328	transposase activity
YPDSF_RS03700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPDSF_RS03710	COG3001	Fructosamine kinase
YPDSF_RS03720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPDSF_RS03725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPDSF_RS03730	COG1121	(ABC) transporter
YPDSF_RS03735	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPDSF_RS03760	COG4249	Peptidase C14 caspase catalytic subunit p20
YPDSF_RS03790	COG0072	phenylalanine-tRNA ligase activity
YPDSF_RS03790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YPDSF_RS03795	COG0776	regulation of translation
YPDSF_RS03810	COG0386	Belongs to the glutathione peroxidase family
YPDSF_RS03855	COG0791	NLP P60 protein
YPDSF_RS03880	COG0574	Belongs to the PEP-utilizing enzyme family
YPDSF_RS03880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPDSF_RS03885	COG0628	permease
YPDSF_RS03890	COG0247	lactate metabolic process
YPDSF_RS03890	COG0277	FAD linked oxidase domain protein
YPDSF_RS03895	COG2050	protein possibly involved in aromatic compounds catabolism
YPDSF_RS03905	COG0316	Belongs to the HesB IscA family
YPDSF_RS03910	COG0719	Fe-S assembly protein
YPDSF_RS03915	COG0396	ATPase activity
YPDSF_RS03920	COG0719	Fe-S assembly protein
YPDSF_RS03935	COG1376	ErfK ybiS ycfS ynhG family protein
YPDSF_RS03935	COG1388	LysM domain
YPDSF_RS03985	COG0307	riboflavin synthase, alpha
YPDSF_RS03990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPDSF_RS03995	COG2814	Major facilitator Superfamily
YPDSF_RS04000	COG0583	DNA-binding transcription factor activity
YPDSF_RS04015	COG0791	NLP P60 protein
YPDSF_RS04025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPDSF_RS04035	COG0346	lactoylglutathione lyase activity
YPDSF_RS04045	COG1902	pentaerythritol trinitrate reductase activity
YPDSF_RS04050	COG1309	transcriptional regulator
YPDSF_RS04055	COG2194	sulfuric ester hydrolase activity
YPDSF_RS04060	COG3313	Fe-S protein
YPDSF_RS04065	COG4989	oxidoreductase activity
YPDSF_RS04075	COG3133	Outer membrane lipoprotein
YPDSF_RS04085	COG3895	Periplasmic Protein
YPDSF_RS04105	COG0625	glutathione transferase activity
YPDSF_RS04120	COG3104	oligopeptide transport
YPDSF_RS04125	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPDSF_RS04125	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPDSF_RS04130	COG4172	Belongs to the ABC transporter superfamily
YPDSF_RS04140	COG4171	peptide transport system, permease
YPDSF_RS04145	COG4168	peptide transport system, permease
YPDSF_RS04150	COG4166	transmembrane transport
YPDSF_RS04170	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPDSF_RS04175	COG1842	Phage shock protein A
YPDSF_RS04185	COG1983	PspC domain protein
YPDSF_RS04195	COG3106	COG3106 Predicted ATPase
YPDSF_RS04205	COG5654	RES domain protein
YPDSF_RS04210	COG5642	Protein of unknown function (DUF2384)
YPDSF_RS04235	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPDSF_RS04240	COG4948	Mandelate Racemase Muconate Lactonizing
YPDSF_RS04245	COG2866	Carboxypeptidase
YPDSF_RS04250	COG4166	transmembrane transport
YPDSF_RS04265	COG0657	acetylesterase activity
YPDSF_RS04275	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPDSF_RS04275	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPDSF_RS04275	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPDSF_RS04275	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPDSF_RS04285	COG1285	pathogenesis
YPDSF_RS04290	COG3042	response to heat
YPDSF_RS04295	COG3187	Heat shock protein
YPDSF_RS04300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPDSF_RS04305	COG2911	Protein conserved in bacteria
YPDSF_RS04315	COG3784	Protein of unknown function (DUF1318)
YPDSF_RS04320	COG0246	Mannitol dehydrogenase
YPDSF_RS04325	COG2390	Transcriptional regulator
YPDSF_RS04335	COG1643	Atp-dependent helicase
YPDSF_RS04350	COG3591	Belongs to the peptidase S1B family
YPDSF_RS04365	COG3038	cytochrome b561
YPDSF_RS04400	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPDSF_RS04405	COG2205	protein histidine kinase activity
YPDSF_RS04410	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS04420	COG0531	amino acid
YPDSF_RS04435	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPDSF_RS04440	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPDSF_RS04445	COG0589	response to stress
YPDSF_RS04450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPDSF_RS04455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPDSF_RS04475	COG1011	Hydrolase
YPDSF_RS04480	COG0440	acetolactate synthase activity
YPDSF_RS04485	COG0028	Belongs to the TPP enzyme family
YPDSF_RS04510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPDSF_RS04520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPDSF_RS04540	COG1609	Transcriptional regulator
YPDSF_RS04555	COG0038	chloride channel
YPDSF_RS04560	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPDSF_RS04565	COG1940	carbohydrate kinase activity
YPDSF_RS04570	COG0583	DNA-binding transcription factor activity
YPDSF_RS04585	COG0114	fumarate hydratase activity
YPDSF_RS04595	COG5339	Protein conserved in bacteria
YPDSF_RS04605	COG0385	Bile acid
YPDSF_RS04610	COG0673	inositol 2-dehydrogenase activity
YPDSF_RS04625	COG1129	ABC transporter
YPDSF_RS04630	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_RS04645	COG2274	protein secretion by the type I secretion system
YPDSF_RS04650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_RS04660	COG1132	(ABC) transporter
YPDSF_RS04690	COG3708	Transcriptional regulator
YPDSF_RS04690	COG2207	Transcriptional regulator
YPDSF_RS04695	COG4658	electron transport chain
YPDSF_RS04700	COG4659	FMN binding
YPDSF_RS04710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPDSF_RS04715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_RS04720	COG2271	Major facilitator Superfamily
YPDSF_RS04730	COG1966	Carbon starvation protein
YPDSF_RS04735	COG2879	small protein
YPDSF_RS04740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPDSF_RS04760	COG0023	Translation Initiation Factor
YPDSF_RS04775	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPDSF_RS04780	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPDSF_RS04785	COG0671	phosphoesterase, PA-phosphatase related
YPDSF_RS04795	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPDSF_RS04805	COG0583	DNA-binding transcription factor activity
YPDSF_RS04835	COG0616	signal peptide processing
YPDSF_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS04850	COG1187	pseudouridine synthase activity
YPDSF_RS04855	COG0009	L-threonylcarbamoyladenylate synthase
YPDSF_RS04880	COG0512	Glutamine amidotransferase of anthranilate synthase
YPDSF_RS04890	COG0134	indole-3-glycerol-phosphate synthase activity
YPDSF_RS04890	COG0135	phosphoribosylanthranilate isomerase activity
YPDSF_RS04910	COG3047	cAMP biosynthetic process
YPDSF_RS04945	COG3328	transposase activity
YPDSF_RS04950	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPDSF_RS04955	COG2350	Protein conserved in bacteria
YPDSF_RS04995	COG4608	Belongs to the ABC transporter superfamily
YPDSF_RS05000	COG0444	Belongs to the ABC transporter superfamily
YPDSF_RS05005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPDSF_RS05010	COG0601	transmembrane transport
YPDSF_RS05020	COG2095	MarC family integral membrane protein
YPDSF_RS05025	COG1454	alcohol dehydrogenase
YPDSF_RS05025	COG1012	belongs to the aldehyde dehydrogenase family
YPDSF_RS05040	COG3328	transposase activity
YPDSF_RS05050	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS05060	COG0788	formyltetrahydrofolate deformylase activity
YPDSF_RS05070	COG3328	transposase activity
YPDSF_RS05075	COG0583	DNA-binding transcription factor activity
YPDSF_RS05080	COG0708	Exodeoxyribonuclease III
YPDSF_RS05085	COG0494	nUDIX hydrolase
YPDSF_RS05095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPDSF_RS05100	COG0709	Synthesizes selenophosphate from selenide and ATP
YPDSF_RS05105	COG0778	Nitroreductase
YPDSF_RS05110	COG0616	signal peptide processing
YPDSF_RS05115	COG0252	asparaginase activity
YPDSF_RS05120	COG1335	isochorismatase
YPDSF_RS05125	COG3139	Protein of unknown function (DUF1315)
YPDSF_RS05145	COG3713	MltA-interacting MipA family protein
YPDSF_RS05150	COG2766	serine protein kinase
YPDSF_RS05165	COG0583	DNA-binding transcription factor activity
YPDSF_RS05175	COG2814	Major facilitator Superfamily
YPDSF_RS05185	COG2719	SpoVR family
YPDSF_RS05215	COG1104	cysteine desulfurase activity
YPDSF_RS05495	COG0582	viral genome integration into host DNA
YPDSF_RS05505	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPDSF_RS05510	COG2951	lytic endotransglycosylase activity
YPDSF_RS05525	COG2894	cell division
YPDSF_RS05530	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPDSF_RS05535	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPDSF_RS05540	COG0318	PFAM AMP-dependent synthetase and ligase
YPDSF_RS05555	COG1199	ATP-dependent helicase activity
YPDSF_RS05560	COG0251	oxidation-reduction process
YPDSF_RS05575	COG0800	Aldolase
YPDSF_RS05580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPDSF_RS05585	COG1737	Transcriptional regulator
YPDSF_RS05590	COG0469	pyruvate kinase activity
YPDSF_RS05595	COG1560	Kdo2-lipid A biosynthetic process
YPDSF_RS05600	COG0739	heme binding
YPDSF_RS05605	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPDSF_RS05615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPDSF_RS05640	COG0494	nUDIX hydrolase
YPDSF_RS05650	COG1801	Protein of unknown function DUF72
YPDSF_RS05655	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPDSF_RS05675	COG3102	Protein conserved in bacteria
YPDSF_RS05695	COG0728	peptidoglycan biosynthetic process
YPDSF_RS05700	COG0673	inositol 2-dehydrogenase activity
YPDSF_RS05705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPDSF_RS05720	COG3381	protein complex oligomerization
YPDSF_RS05735	COG1940	carbohydrate kinase activity
YPDSF_RS05740	COG0584	glycerophosphoryl diester phosphodiesterase
YPDSF_RS05745	COG3842	ATPase activity
YPDSF_RS05760	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPDSF_RS05765	COG3833	ABC-type maltose transport systems, permease component
YPDSF_RS05790	COG0659	secondary active sulfate transmembrane transporter activity
YPDSF_RS05810	COG2890	protein-(glutamine-N5) methyltransferase activity
YPDSF_RS05840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPDSF_RS05860	COG0012	GTP binding
YPDSF_RS05910	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS05930	COG5002	protein histidine kinase activity
YPDSF_RS05970	COG0500	methyltransferase
YPDSF_RS05995	COG3328	transposase activity
YPDSF_RS06040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_RS06045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPDSF_RS06050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPDSF_RS06065	COG0402	S-adenosylhomocysteine deaminase activity
YPDSF_RS06095	COG3328	transposase activity
YPDSF_RS06135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPDSF_RS06140	COG3850	Histidine kinase
YPDSF_RS06145	COG0387	Pfam Sodium calcium exchanger
YPDSF_RS06150	COG1702	phosphate starvation-inducible protein PhoH
YPDSF_RS06165	COG3658	cytochrome
YPDSF_RS06170	COG1215	transferase activity, transferring glycosyl groups
YPDSF_RS06175	COG0726	polysaccharide deacetylase
YPDSF_RS06175	COG1649	PFAM Uncharacterised BCR, COG1649
YPDSF_RS06180	COG0457	Tetratricopeptide repeat
YPDSF_RS06185	COG0006	proline dipeptidase activity
YPDSF_RS06205	COG1136	(ABC) transporter
YPDSF_RS06205	COG0577	efflux transmembrane transporter activity
YPDSF_RS06215	COG1136	(ABC) transporter
YPDSF_RS06215	COG0577	efflux transmembrane transporter activity
YPDSF_RS06240	COG2066	Belongs to the glutaminase family
YPDSF_RS06245	COG1349	DNA-binding transcription factor activity
YPDSF_RS06255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPDSF_RS06260	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPDSF_RS06275	COG2814	Major facilitator Superfamily
YPDSF_RS06300	COG2030	dehydratase
YPDSF_RS06305	COG0427	acetyl-CoA hydrolase
YPDSF_RS06315	COG2205	protein histidine kinase activity
YPDSF_RS06315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_RS06330	COG3188	usher protein
YPDSF_RS06340	COG3121	Chaperone
YPDSF_RS06345	COG3328	transposase activity
YPDSF_RS06360	COG0582	viral genome integration into host DNA
YPDSF_RS06365	COG1169	isochorismate synthase
YPDSF_RS06370	COG2814	Major facilitator Superfamily
YPDSF_RS06375	COG1132	(ABC) transporter
YPDSF_RS06390	COG3433	isochorismatase activity
YPDSF_RS06390	COG2226	methyltransferase
YPDSF_RS06390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPDSF_RS06410	COG1021	2,3-dihydroxybenzoate-AMP ligase
YPDSF_RS06415	COG4771	TonB-dependent receptor
YPDSF_RS06490	COG3842	ATPase activity
YPDSF_RS06495	COG0395	ABC-type sugar transport system, permease component
YPDSF_RS06500	COG1175	transmembrane transport
YPDSF_RS06510	COG0673	inositol 2-dehydrogenase activity
YPDSF_RS06520	COG2188	Transcriptional regulator
YPDSF_RS06660	COG2197	response regulator
YPDSF_RS06670	COG3136	membrane protein required for alginate biosynthesis
YPDSF_RS06690	COG1113	amino acid transport
YPDSF_RS06710	COG2822	iron ion transport
YPDSF_RS06715	COG0672	)-iron permease
YPDSF_RS06730	COG0506	proline dehydrogenase activity
YPDSF_RS06730	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPDSF_RS06730	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPDSF_RS06745	COG1126	abc transporter atp-binding protein
YPDSF_RS06750	COG0765	amino acid transport
YPDSF_RS06770	COG1191	sigma factor activity
YPDSF_RS06805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPDSF_RS06810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPDSF_RS06825	COG1677	Flagellar hook-basal body complex protein FliE
YPDSF_RS06845	COG1157	protein secretion by the type III secretion system
YPDSF_RS06860	COG1580	Controls the rotational direction of flagella during chemotaxis
YPDSF_RS06885	COG1987	bacterial-type flagellum assembly
YPDSF_RS06905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_RS06910	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS06915	COG1129	ABC transporter
YPDSF_RS06925	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS06930	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS06930	COG3347	Dehydrogenase
YPDSF_RS06935	COG2390	Transcriptional regulator
YPDSF_RS06945	COG1256	bacterial-type flagellum assembly
YPDSF_RS06985	COG1558	bacterial-type flagellum-dependent cell motility
YPDSF_RS06990	COG1815	bacterial-type flagellum-dependent cell motility
YPDSF_RS07000	COG2747	anti-sigma28 factor FlgM
YPDSF_RS07005	COG3418	PFAM FlgN family protein
YPDSF_RS07030	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPDSF_RS07035	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPDSF_RS07065	COG2372	response to copper ion
YPDSF_RS07070	COG1528	Iron-storage protein
YPDSF_RS07085	COG1770	oligopeptidase
YPDSF_RS07100	COG3141	response to X-ray
YPDSF_RS07105	COG0513	Belongs to the DEAD box helicase family
YPDSF_RS07130	COG1760	l-serine dehydratase
YPDSF_RS07135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPDSF_RS07140	COG2368	4-hydroxyphenylacetate
YPDSF_RS07155	COG3971	2-oxopent-4-enoate hydratase activity
YPDSF_RS07165	COG3384	dioxygenase
YPDSF_RS07170	COG1012	belongs to the aldehyde dehydrogenase family
YPDSF_RS07185	COG1846	Transcriptional regulator
YPDSF_RS07195	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_RS07195	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_RS07200	COG3715	PTS system
YPDSF_RS07205	COG3716	PTS system mannose fructose sorbose family IID component
YPDSF_RS07225	COG5001	Diguanylate cyclase
YPDSF_RS07225	COG5002	protein histidine kinase activity
YPDSF_RS07225	COG3447	MASE1 domain protein
YPDSF_RS07235	COG2226	methyltransferase
YPDSF_RS07240	COG1496	oxidoreductase activity
YPDSF_RS07265	COG1113	amino acid transport
YPDSF_RS07300	COG2207	Transcriptional regulator
YPDSF_RS07310	COG1132	(ABC) transporter
YPDSF_RS07350	COG2223	nitrite transmembrane transporter activity
YPDSF_RS07370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPDSF_RS07395	COG3122	Protein conserved in bacteria
YPDSF_RS07415	COG0534	Mate efflux family protein
YPDSF_RS07430	COG4948	Mandelate Racemase Muconate Lactonizing
YPDSF_RS07440	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS07445	COG3011	Protein conserved in bacteria
YPDSF_RS07450	COG2271	Major facilitator Superfamily
YPDSF_RS07455	COG1470	cell adhesion involved in biofilm formation
YPDSF_RS07455	COG1388	LysM domain
YPDSF_RS07460	COG3328	transposase activity
YPDSF_RS07475	COG2925	Exonuclease
YPDSF_RS07480	COG0531	amino acid
YPDSF_RS07490	COG0371	Dehydrogenase
YPDSF_RS07500	COG1129	ABC transporter
YPDSF_RS07505	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS07515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_RS07525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPDSF_RS07535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPDSF_RS07535	COG0131	Imidazoleglycerol-phosphate dehydratase
YPDSF_RS07555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPDSF_RS07555	COG0140	phosphoribosyl-ATP diphosphatase activity
YPDSF_RS07565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPDSF_RS07570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPDSF_RS07585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPDSF_RS07590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_RS07595	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_RS07600	COG1120	ATPase activity
YPDSF_RS07615	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPDSF_RS07620	COG0076	glutamate decarboxylase activity
YPDSF_RS07625	COG4114	ferric iron reductase
YPDSF_RS07630	COG1253	flavin adenine dinucleotide binding
YPDSF_RS07635	COG2982	Protein involved in outer membrane biogenesis
YPDSF_RS07650	COG0489	protein tyrosine kinase activity
YPDSF_RS07685	COG2814	Major facilitator Superfamily
YPDSF_RS07695	COG1346	cytolysis
YPDSF_RS07710	COG2949	membrane
YPDSF_RS07730	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS07745	COG2311	Membrane
YPDSF_RS07755	COG0477	Major facilitator Superfamily
YPDSF_RS07760	COG0583	DNA-binding transcription factor activity
YPDSF_RS07790	COG1136	(ABC) transporter
YPDSF_RS07800	COG0303	'Molybdopterin
YPDSF_RS07815	COG0488	(ABC) transporter
YPDSF_RS07950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPDSF_RS07955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPDSF_RS07965	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS07970	COG1024	Enoyl-CoA hydratase
YPDSF_RS07980	COG3425	synthase
YPDSF_RS07985	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS07990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_RS07995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPDSF_RS08005	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS08040	COG2920	part of a sulfur-relay system
YPDSF_RS08060	COG1832	CoA-binding protein
YPDSF_RS08075	COG0210	DNA helicase
YPDSF_RS08080	COG3304	Inner membrane component domain
YPDSF_RS08085	COG1289	transmembrane transporter activity
YPDSF_RS08090	COG3070	regulator of competence-specific genes
YPDSF_RS08120	COG1067	ATP-dependent peptidase activity
YPDSF_RS08135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_RS08150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_RS08170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YPDSF_RS08205	COG3086	response to oxidative stress
YPDSF_RS08210	COG3026	antisigma factor binding
YPDSF_RS08225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPDSF_RS08235	COG0513	Belongs to the DEAD box helicase family
YPDSF_RS08285	COG1984	allophanate hydrolase subunit 2
YPDSF_RS08295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPDSF_RS08300	COG5212	phosphodiesterase
YPDSF_RS08310	COG3272	Protein of unknown function (DUF1722)
YPDSF_RS08350	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS08370	COG0033	Phosphoglucomutase
YPDSF_RS08375	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPDSF_RS08395	COG2169	Transcriptional regulator
YPDSF_RS08395	COG1917	Cupin 2, conserved barrel domain protein
YPDSF_RS08400	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPDSF_RS08405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPDSF_RS08410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPDSF_RS08420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPDSF_RS08430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPDSF_RS08445	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPDSF_RS08450	COG4413	Urea transporter
YPDSF_RS08460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPDSF_RS08485	COG0831	urea catabolic process
YPDSF_RS08490	COG1124	(ABC) transporter
YPDSF_RS08495	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPDSF_RS08500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPDSF_RS08510	COG0747	negative chemotaxis
YPDSF_RS08515	COG1278	Cold shock
YPDSF_RS08555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPDSF_RS08560	COG4175	Glycine betaine
YPDSF_RS08565	COG4176	ABC-type proline glycine betaine transport system permease component
YPDSF_RS08570	COG2113	Glycine betaine
YPDSF_RS08585	COG1953	Uracil, thiamine, allantoin
YPDSF_RS08605	COG2226	methyltransferase
YPDSF_RS08615	COG1388	LysM domain
YPDSF_RS08615	COG0741	lytic transglycosylase activity
YPDSF_RS08630	COG0656	L-ascorbic acid biosynthetic process
YPDSF_RS08665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPDSF_RS08675	COG2011	ABC-type metal ion transport system permease component
YPDSF_RS08680	COG1464	Belongs to the NlpA lipoprotein family
YPDSF_RS08690	COG1720	tRNA m6t6A37 methyltransferase activity
YPDSF_RS08700	COG3015	lipoprotein NlpE involved in copper resistance
YPDSF_RS08710	COG4681	YaeQ
YPDSF_RS08720	COG4568	rho-dependent transcription termination
YPDSF_RS08730	COG0037	tRNA processing
YPDSF_RS08735	COG0346	lactoylglutathione lyase activity
YPDSF_RS08745	COG0587	DNA-directed DNA polymerase activity
YPDSF_RS08770	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPDSF_RS08785	COG0750	zinc metalloprotease
YPDSF_RS08790	COG0575	Belongs to the CDS family
YPDSF_RS08850	COG0564	pseudouridine synthase activity
YPDSF_RS08855	COG3098	single-species biofilm formation
YPDSF_RS08875	COG1611	Belongs to the LOG family
YPDSF_RS08890	COG2363	Small membrane protein
YPDSF_RS08895	COG0583	DNA-binding transcription factor activity
YPDSF_RS08900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPDSF_RS08905	COG2166	iron-sulfur cluster assembly
YPDSF_RS08910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPDSF_RS08915	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPDSF_RS08935	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPDSF_RS08940	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YPDSF_RS08940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YPDSF_RS08960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPDSF_RS08965	COG1074	ATP-dependent DNA helicase activity
YPDSF_RS08975	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPDSF_RS09040	COG0667	Aldo Keto reductase
YPDSF_RS09070	COG1609	Transcriptional regulator
YPDSF_RS09080	COG0583	DNA-binding transcription factor activity
YPDSF_RS09085	COG2814	Major facilitator Superfamily
YPDSF_RS09090	COG0583	DNA-binding transcription factor activity
YPDSF_RS09105	COG0840	transmembrane signaling receptor activity
YPDSF_RS09120	COG3328	transposase activity
YPDSF_RS09125	COG1917	Cupin 2, conserved barrel domain protein
YPDSF_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS09145	COG1175	transmembrane transport
YPDSF_RS09150	COG0395	ABC-type sugar transport system, permease component
YPDSF_RS09155	COG3842	ATPase activity
YPDSF_RS09160	COG1653	transport
YPDSF_RS09165	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPDSF_RS09170	COG1988	membrane-bound metal-dependent
YPDSF_RS09175	COG1823	symporter activity
YPDSF_RS09180	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPDSF_RS09190	COG0823	Involved in the tonB-independent uptake of proteins
YPDSF_RS09195	COG2814	Major facilitator Superfamily
YPDSF_RS09200	COG3121	Chaperone
YPDSF_RS09215	COG3121	Chaperone
YPDSF_RS09220	COG3539	Fimbrial protein
YPDSF_RS09230	COG0793	Belongs to the peptidase S41A family
YPDSF_RS09240	COG1956	GAF domain-containing protein
YPDSF_RS09245	COG2995	paraquat-inducible protein a
YPDSF_RS09250	COG3008	intermembrane lipid transfer
YPDSF_RS09270	COG3121	Chaperone
YPDSF_RS09325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPDSF_RS09335	COG5295	Hep Hag repeat protein
YPDSF_RS09345	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPDSF_RS09355	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPDSF_RS09360	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS09370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPDSF_RS09375	COG0840	transmembrane signaling receptor activity
YPDSF_RS09380	COG0840	transmembrane signaling receptor activity
YPDSF_RS09400	COG2964	Protein conserved in bacteria
YPDSF_RS09410	COG0251	oxidation-reduction process
YPDSF_RS09415	COG2271	Major facilitator Superfamily
YPDSF_RS09420	COG0835	chemotaxis
YPDSF_RS09425	COG2198	Histidine kinase
YPDSF_RS09425	COG0643	Histidine kinase
YPDSF_RS09430	COG1360	Flagellar Motor Protein
YPDSF_RS09455	COG1285	pathogenesis
YPDSF_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS09485	COG0604	alcohol dehydrogenase
YPDSF_RS09485	COG3321	synthase
YPDSF_RS09495	COG1522	sequence-specific DNA binding
YPDSF_RS09520	COG1733	regulation of RNA biosynthetic process
YPDSF_RS09525	COG0702	epimerase
YPDSF_RS09530	COG0840	transmembrane signaling receptor activity
YPDSF_RS09545	COG0538	isocitrate dehydrogenase activity
YPDSF_RS09550	COG1187	pseudouridine synthase activity
YPDSF_RS09570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPDSF_RS09580	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS09590	COG2850	peptidyl-arginine hydroxylation
YPDSF_RS09605	COG1940	carbohydrate kinase activity
YPDSF_RS09610	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPDSF_RS09620	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPDSF_RS09625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPDSF_RS09630	COG3134	Outer membrane lipoprotein
YPDSF_RS09635	COG3328	transposase activity
YPDSF_RS09650	COG1252	NADH dehydrogenase
YPDSF_RS09660	COG1472	Belongs to the glycosyl hydrolase 3 family
YPDSF_RS09675	COG5633	Lipoprotein
YPDSF_RS09680	COG0537	adenosine 5'-monophosphoramidase activity
YPDSF_RS09685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPDSF_RS09695	COG1263	PTS System
YPDSF_RS09695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_RS09700	COG0084	hydrolase, TatD family'
YPDSF_RS09705	COG0470	DNA polymerase III
YPDSF_RS09715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPDSF_RS09720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPDSF_RS09730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_RS09760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPDSF_RS09765	COG1399	metal-binding, possibly nucleic acid-binding protein
YPDSF_RS09770	COG0424	maF-like protein
YPDSF_RS09775	COG0564	pseudouridine synthase activity
YPDSF_RS09780	COG1530	ribonuclease E activity
YPDSF_RS09785	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPDSF_RS09810	COG3328	transposase activity
YPDSF_RS09825	COG0628	permease
YPDSF_RS09855	COG3916	Acyl-homoserine-lactone synthase
YPDSF_RS09860	COG2771	luxR family
YPDSF_RS09865	COG0583	DNA-binding transcription factor activity
YPDSF_RS09875	COG0477	Major facilitator Superfamily
YPDSF_RS09885	COG0667	Aldo Keto reductase
YPDSF_RS09910	COG1203	CRISPR-associated helicase, Cas3
YPDSF_RS09915	COG1518	maintenance of DNA repeat elements
YPDSF_RS09920	COG0668	transmembrane transport
YPDSF_RS09940	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPDSF_RS09945	COG0395	ABC-type sugar transport system, permease component
YPDSF_RS09960	COG1609	Transcriptional regulator
YPDSF_RS09970	COG3842	ATPase activity
YPDSF_RS09980	COG3210	domain, Protein
YPDSF_RS10000	COG3210	domain, Protein
YPDSF_RS10020	COG3210	domain, Protein
YPDSF_RS10025	COG2831	hemolysin activation secretion protein
YPDSF_RS10030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_RS10035	COG4638	Rieske (2fe-2S)
YPDSF_RS10040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPDSF_RS10050	COG0473	3-isopropylmalate dehydrogenase activity
YPDSF_RS10055	COG0583	DNA-binding transcription factor activity
YPDSF_RS10060	COG1609	Transcriptional regulator
YPDSF_RS10065	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS10075	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_RS10080	COG1063	alcohol dehydrogenase
YPDSF_RS10100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPDSF_RS10130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_RS10135	COG0765	amino acid transport
YPDSF_RS10140	COG1126	abc transporter atp-binding protein
YPDSF_RS10160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPDSF_RS10175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPDSF_RS10190	COG1169	isochorismate synthase
YPDSF_RS10200	COG4575	ribosome binding
YPDSF_RS10215	COG0129	dihydroxy-acid dehydratase activity
YPDSF_RS10230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPDSF_RS10240	COG1609	Transcriptional regulator
YPDSF_RS10245	COG1649	PFAM Uncharacterised BCR, COG1649
YPDSF_RS10250	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS10255	COG3265	gluconokinase activity
YPDSF_RS10260	COG2731	YhcH YjgK YiaL family protein
YPDSF_RS10275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPDSF_RS10280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPDSF_RS10290	COG0839	Belongs to the complex I subunit 6 family
YPDSF_RS10305	COG1034	ATP synthesis coupled electron transport
YPDSF_RS10325	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPDSF_RS10335	COG0583	DNA-binding transcription factor activity
YPDSF_RS10345	COG0436	Aminotransferase
YPDSF_RS10360	COG0490	domain, Protein
YPDSF_RS10360	COG0471	metal ion transport
YPDSF_RS10365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPDSF_RS10390	COG0857	belongs to the CobB CobQ family
YPDSF_RS10390	COG0280	phosphate acetyltransferase
YPDSF_RS10395	COG1609	Transcriptional regulator
YPDSF_RS10410	COG3037	sugar-specific permease SgaT UlaA
YPDSF_RS10415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPDSF_RS10430	COG1090	epimerase
YPDSF_RS10435	COG4598	ABC transporter
YPDSF_RS10440	COG4160	amino acid transport
YPDSF_RS10445	COG4215	(ABC) transporter
YPDSF_RS10450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_RS10460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPDSF_RS10465	COG1286	toxin biosynthetic process
YPDSF_RS10470	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPDSF_RS10475	COG0285	dihydrofolate synthase activity
YPDSF_RS10485	COG0586	Pfam SNARE associated Golgi protein
YPDSF_RS10495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPDSF_RS10515	COG0697	spore germination
YPDSF_RS10530	COG1794	racemase activity, acting on amino acids and derivatives
YPDSF_RS10535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPDSF_RS10550	COG3101	peptidyl-lysine hydroxylation
YPDSF_RS10555	COG0730	response to heat
YPDSF_RS10570	COG2890	protein-(glutamine-N5) methyltransferase activity
YPDSF_RS10580	COG2062	phosphohistidine phosphatase, SixA
YPDSF_RS10595	COG3691	Protein conserved in bacteria
YPDSF_RS10610	COG3088	subunit of a heme lyase
YPDSF_RS10610	COG4235	cytochrome complex assembly
YPDSF_RS10615	COG4235	cytochrome complex assembly
YPDSF_RS10615	COG3088	subunit of a heme lyase
YPDSF_RS10620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPDSF_RS10625	COG1138	Cytochrome C-type biogenesis protein
YPDSF_RS10635	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPDSF_RS10640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPDSF_RS10645	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPDSF_RS10665	COG1704	LemA family
YPDSF_RS10675	COG2824	Alkylphosphonate utilization operon protein PhnA
YPDSF_RS10765	COG3188	usher protein
YPDSF_RS10770	COG3328	transposase activity
YPDSF_RS10775	COG3188	usher protein
YPDSF_RS10780	COG3121	Chaperone
YPDSF_RS10840	COG2951	lytic endotransglycosylase activity
YPDSF_RS10875	COG0243	molybdopterin cofactor binding
YPDSF_RS10880	COG0437	4 iron, 4 sulfur cluster binding
YPDSF_RS10885	COG3302	dmso reductase anchor subunit
YPDSF_RS10890	COG3381	protein complex oligomerization
YPDSF_RS10920	COG3038	cytochrome b561
YPDSF_RS10925	COG0436	Aminotransferase
YPDSF_RS10950	COG0667	Aldo Keto reductase
YPDSF_RS11015	COG3530	Putative quorum-sensing-regulated virulence factor
YPDSF_RS11030	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPDSF_RS11040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_RS11065	COG2205	protein histidine kinase activity
YPDSF_RS11070	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS11075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_RS11090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPDSF_RS11110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPDSF_RS11120	COG3850	Histidine kinase
YPDSF_RS11120	COG5002	protein histidine kinase activity
YPDSF_RS11125	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS11140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YPDSF_RS11145	COG4208	sulfate ABC transporter
YPDSF_RS11150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPDSF_RS11155	COG4150	thiosulfate binding
YPDSF_RS11165	COG1737	Transcriptional regulator
YPDSF_RS11175	COG2731	YhcH YjgK YiaL family protein
YPDSF_RS11185	COG4886	Leucine-rich repeat (LRR) protein
YPDSF_RS11195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPDSF_RS11200	COG2837	iron assimilation
YPDSF_RS11210	COG3111	PFAM Bacterial OB fold (BOF) protein
YPDSF_RS11255	COG3005	denitrification pathway
YPDSF_RS11260	COG3043	anaerobic respiration
YPDSF_RS11270	COG3062	negative regulation of establishment of protein localization
YPDSF_RS11275	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_RS11275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_RS11280	COG2197	response regulator
YPDSF_RS11290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPDSF_RS11300	COG1988	membrane-bound metal-dependent
YPDSF_RS11305	COG0641	radical SAM
YPDSF_RS11310	COG3119	arylsulfatase activity
YPDSF_RS11315	COG3842	ATPase activity
YPDSF_RS11320	COG1175	transmembrane transport
YPDSF_RS11335	COG1393	Belongs to the ArsC family
YPDSF_RS11345	COG1876	peptidase activity
YPDSF_RS11365	COG2321	neutral zinc metallopeptidase
YPDSF_RS11385	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPDSF_RS11395	COG2716	regulation of RNA biosynthetic process
YPDSF_RS11400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPDSF_RS11420	COG0628	permease
YPDSF_RS11425	COG4783	chaperone-mediated protein folding
YPDSF_RS11430	COG1393	Belongs to the ArsC family
YPDSF_RS11455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPDSF_RS11460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPDSF_RS11480	COG0581	inorganic phosphate transmembrane transporter activity
YPDSF_RS11490	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPDSF_RS11505	COG2239	Acts as a magnesium transporter
YPDSF_RS11510	COG0443	Heat shock 70 kDa protein
YPDSF_RS11515	COG1177	transmembrane transport
YPDSF_RS11520	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPDSF_RS11530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPDSF_RS11540	COG3842	ATPase activity
YPDSF_RS11565	COG2205	protein histidine kinase activity
YPDSF_RS11570	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS11575	COG3422	double-strand break repair
YPDSF_RS11580	COG0826	peptidase U32
YPDSF_RS11600	COG0351	phosphomethylpyrimidine kinase
YPDSF_RS11615	COG3328	transposase activity
YPDSF_RS11670	COG0517	IMP dehydrogenase activity
YPDSF_RS11670	COG0516	GMP reductase activity
YPDSF_RS11680	COG1645	bacterial-type flagellum-dependent swarming motility
YPDSF_RS11695	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPDSF_RS11700	COG2976	Protein conserved in bacteria
YPDSF_RS11745	COG3468	outer membrane autotransporter barrel domain protein
YPDSF_RS11750	COG3468	outer membrane autotransporter barrel domain protein
YPDSF_RS11770	COG2975	iron-sulfur cluster assembly
YPDSF_RS11775	COG0633	Ferredoxin
YPDSF_RS11780	COG0443	Heat shock 70 kDa protein
YPDSF_RS11795	COG0822	iron-sulfur transferase activity
YPDSF_RS11800	COG1104	cysteine desulfurase activity
YPDSF_RS11820	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPDSF_RS11825	COG3683	transport system, periplasmic component
YPDSF_RS11830	COG3711	transcriptional antiterminator
YPDSF_RS11835	COG2814	Major facilitator Superfamily
YPDSF_RS11855	COG1017	nitric oxide dioxygenase activity
YPDSF_RS11855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_RS11870	COG2188	Transcriptional regulator
YPDSF_RS11875	COG0347	Belongs to the P(II) protein family
YPDSF_RS11880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPDSF_RS11880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPDSF_RS11885	COG2204	response regulator
YPDSF_RS11890	COG3170	Tfp pilus assembly protein FimV
YPDSF_RS11895	COG2205	protein histidine kinase activity
YPDSF_RS11935	COG0560	Phosphoserine phosphatase
YPDSF_RS11945	COG1737	Transcriptional regulator
YPDSF_RS11950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_RS11965	COG3130	regulation of translation
YPDSF_RS11975	COG3009	Protein conserved in bacteria
YPDSF_RS11980	COG3008	intermembrane lipid transfer
YPDSF_RS11980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPDSF_RS11985	COG2995	paraquat-inducible protein a
YPDSF_RS11990	COG0488	(ABC) transporter
YPDSF_RS12000	COG0633	Ferredoxin
YPDSF_RS12000	COG3217	Mosc domain protein beta barrel domain protein
YPDSF_RS12015	COG0308	aminopeptidase N
YPDSF_RS12035	COG1448	Aminotransferase
YPDSF_RS12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPDSF_RS12045	COG3108	Peptidase M15
YPDSF_RS12050	COG2989	Protein conserved in bacteria
YPDSF_RS12080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPDSF_RS12090	COG3173	Aminoglycoside phosphotransferase
YPDSF_RS12105	COG1278	Cold shock
YPDSF_RS12115	COG5383	Protein conserved in bacteria
YPDSF_RS12130	COG0658	competence protein
YPDSF_RS12130	COG2333	competence protein COMEC
YPDSF_RS12145	COG0539	negative regulation of cytoplasmic translation
YPDSF_RS12170	COG5295	Hep Hag repeat protein
YPDSF_RS12170	COG5295	Hep Hag repeat protein
YPDSF_RS12175	COG0252	asparaginase activity
YPDSF_RS12180	COG1944	ATP diphosphatase activity
YPDSF_RS12185	COG2116	formate transmembrane transporter activity
YPDSF_RS12190	COG1882	Formate acetyltransferase
YPDSF_RS12200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPDSF_RS12215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPDSF_RS12225	COG3107	peptidoglycan biosynthetic process
YPDSF_RS12225	COG1674	ftsk spoiiie
YPDSF_RS12235	COG0492	ferredoxin-NADP+ reductase activity
YPDSF_RS12250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPDSF_RS12260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPDSF_RS12270	COG0542	response to heat
YPDSF_RS12280	COG1278	Cold shock
YPDSF_RS12290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_RS12295	COG2990	Protein conserved in bacteria
YPDSF_RS12300	COG3593	DNA synthesis involved in DNA repair
YPDSF_RS12305	COG2431	L-lysine efflux transmembrane transporter activity
YPDSF_RS12315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_RS12320	COG0028	Belongs to the TPP enzyme family
YPDSF_RS12325	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPDSF_RS12330	COG0702	epimerase
YPDSF_RS12335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_RS12345	COG1605	Chorismate mutase
YPDSF_RS12350	COG1126	abc transporter atp-binding protein
YPDSF_RS12355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_RS12360	COG4215	(ABC) transporter
YPDSF_RS12365	COG4160	amino acid transport
YPDSF_RS12390	COG1120	ATPase activity
YPDSF_RS12420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_RS12435	COG1177	transmembrane transport
YPDSF_RS12440	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPDSF_RS12445	COG3842	ATPase activity
YPDSF_RS12450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPDSF_RS12485	COG0671	phosphoesterase, PA-phosphatase related
YPDSF_RS12495	COG1349	DNA-binding transcription factor activity
YPDSF_RS12500	COG0814	amino acid
YPDSF_RS12510	COG1686	Belongs to the peptidase S11 family
YPDSF_RS12515	COG2011	ABC-type metal ion transport system permease component
YPDSF_RS12540	COG0625	glutathione transferase activity
YPDSF_RS12545	COG4771	TonB-dependent receptor
YPDSF_RS12555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_RS12570	COG0833	amino acid
YPDSF_RS12575	COG0583	DNA-binding transcription factor activity
YPDSF_RS12580	COG2855	membrane
YPDSF_RS12590	COG3188	usher protein
YPDSF_RS12595	COG3121	Chaperone
YPDSF_RS12610	COG3710	Transcriptional regulator
YPDSF_RS12615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_RS12615	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPDSF_RS12615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_RS12620	COG1105	Belongs to the carbohydrate kinase PfkB family
YPDSF_RS12630	COG0494	nUDIX hydrolase
YPDSF_RS12640	COG1129	ABC transporter
YPDSF_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS12700	COG0246	Mannitol dehydrogenase
YPDSF_RS12715	COG0523	cobalamin synthesis protein
YPDSF_RS12720	COG0671	phosphoesterase, PA-phosphatase related
YPDSF_RS12725	COG0791	NLP P60 protein
YPDSF_RS12730	COG2200	EAL domain
YPDSF_RS12735	COG4166	transmembrane transport
YPDSF_RS12740	COG4174	ABC transporter (Permease)
YPDSF_RS12745	COG4239	(ABC) transporter, permease
YPDSF_RS12750	COG4172	Belongs to the ABC transporter superfamily
YPDSF_RS12760	COG2814	Major facilitator Superfamily
YPDSF_RS12765	COG1187	pseudouridine synthase activity
YPDSF_RS12770	COG1061	Type III restriction enzyme res subunit
YPDSF_RS12790	COG3082	Protein of unknown function (DUF1414)
YPDSF_RS12795	COG3083	sulfuric ester hydrolase activity
YPDSF_RS12810	COG3157	Type VI secretion system effector, Hcp
YPDSF_RS12830	COG2723	6-phospho-beta-galactosidase activity
YPDSF_RS12835	COG1737	Transcriptional regulator
YPDSF_RS12855	COG3299	homolog of phage Mu protein gp47
YPDSF_RS12895	COG4386	tail sheath protein
YPDSF_RS12915	COG3622	Belongs to the hyi family
YPDSF_RS12920	COG1349	DNA-binding transcription factor activity
YPDSF_RS12925	COG0235	Class ii aldolase
YPDSF_RS12930	COG3395	kinase activity
YPDSF_RS12975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPDSF_RS13005	COG2198	Histidine kinase
YPDSF_RS13005	COG0642	Histidine kinase
YPDSF_RS13010	COG2198	Histidine kinase
YPDSF_RS13010	COG0642	Histidine kinase
YPDSF_RS13020	COG2205	protein histidine kinase activity
YPDSF_RS13020	COG0784	Response regulator, receiver
YPDSF_RS13050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_RS13065	COG0814	amino acid
YPDSF_RS13090	COG0697	spore germination
YPDSF_RS13100	COG1982	Orn Lys Arg decarboxylase major
YPDSF_RS13105	COG3328	transposase activity
YPDSF_RS13110	COG1982	Orn Lys Arg decarboxylase major
YPDSF_RS13115	COG0531	amino acid
YPDSF_RS13120	COG1174	glycine betaine transport
YPDSF_RS13125	COG1125	glycine betaine transport
YPDSF_RS13130	COG1174	glycine betaine transport
YPDSF_RS13135	COG1732	Glycine betaine
YPDSF_RS13140	COG2897	thiosulfate sulfurtransferase activity
YPDSF_RS13160	COG1122	ATPase activity
YPDSF_RS13180	COG4807	Protein conserved in bacteria
YPDSF_RS13195	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPDSF_RS13205	COG2261	transglycosylase associated protein
YPDSF_RS13225	COG0277	FAD linked oxidase domain protein
YPDSF_RS13230	COG1686	Belongs to the peptidase S11 family
YPDSF_RS13240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPDSF_RS13255	COG2211	Major facilitator Superfamily
YPDSF_RS13260	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPDSF_RS13270	COG0583	DNA-binding transcription factor activity
YPDSF_RS13275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPDSF_RS13305	COG0670	Belongs to the BI1 family
YPDSF_RS13310	COG0314	molybdopterin synthase activity
YPDSF_RS13315	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPDSF_RS13325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPDSF_RS13335	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPDSF_RS13340	COG4628	conserved protein (DUF2132)
YPDSF_RS13350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YPDSF_RS13360	COG2226	methyltransferase
YPDSF_RS13385	COG0561	phosphatase activity
YPDSF_RS13395	COG4149	molybdate abc transporter
YPDSF_RS13400	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPDSF_RS13410	COG3585	molybdate ion transport
YPDSF_RS13410	COG2005	Transcriptional regulator
YPDSF_RS13415	COG1119	ATPase activity
YPDSF_RS13430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPDSF_RS13435	COG1085	galactose-1-phosphate uridylyltransferase
YPDSF_RS13450	COG2017	converts alpha-aldose to the beta-anomer
YPDSF_RS13470	COG1230	cation diffusion facilitator family transporter
YPDSF_RS13505	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPDSF_RS13510	COG2885	chlorophyll binding
YPDSF_RS13520	COG3064	Membrane
YPDSF_RS13520	COG3064	Membrane
YPDSF_RS13525	COG0848	biopolymer transport protein
YPDSF_RS13530	COG0811	peptide transport
YPDSF_RS13535	COG0824	Thioesterase
YPDSF_RS13540	COG3790	cyd operon protein YbgE
YPDSF_RS13545	COG4890	Cyd operon protein YbgT
YPDSF_RS13550	COG1294	oxidase, subunit
YPDSF_RS13555	COG1271	oxidase subunit
YPDSF_RS13565	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPDSF_RS13575	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPDSF_RS13580	COG0567	Dehydrogenase, E1 component
YPDSF_RS13590	COG1053	succinate dehydrogenase
YPDSF_RS13595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPDSF_RS13600	COG2009	succinate dehydrogenase
YPDSF_RS13615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YPDSF_RS13620	COG0497	DNA recombination
YPDSF_RS13625	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPDSF_RS13635	COG2867	negative regulation of translational initiation
YPDSF_RS13655	COG0582	viral genome integration into host DNA
YPDSF_RS13715	COG3657	addiction module killer protein
YPDSF_RS13735	COG0582	viral genome integration into host DNA
YPDSF_RS13740	COG2963	transposase activity
YPDSF_RS13745	COG0582	viral genome integration into host DNA
YPDSF_RS13755	COG0596	Alpha beta hydrolase
YPDSF_RS13775	COG0735	belongs to the Fur family
YPDSF_RS13795	COG1263	PTS System
YPDSF_RS13795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPDSF_RS13795	COG2190	(PTS) system
YPDSF_RS13805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPDSF_RS13810	COG1846	Transcriptional regulator
YPDSF_RS13810	COG1940	carbohydrate kinase activity
YPDSF_RS13815	COG0647	UMP catabolic process
YPDSF_RS13820	COG0367	asparagine synthase
YPDSF_RS13860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPDSF_RS13870	COG1702	phosphate starvation-inducible protein PhoH
YPDSF_RS13880	COG4535	Mg2 and Co2 transporter CorC
YPDSF_RS13885	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPDSF_RS13895	COG0765	amino acid transport
YPDSF_RS13900	COG0765	amino acid transport
YPDSF_RS13905	COG1126	abc transporter atp-binding protein
YPDSF_RS13910	COG2888	peptidyl-tyrosine sulfation
YPDSF_RS13925	COG1466	dna polymerase III delta subunit
YPDSF_RS13935	COG0799	negative regulation of ribosome biogenesis
YPDSF_RS13945	COG0768	penicillin binding
YPDSF_RS13950	COG0772	Belongs to the SEDS family
YPDSF_RS13955	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPDSF_RS13960	COG1686	Belongs to the peptidase S11 family
YPDSF_RS13980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPDSF_RS13990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPDSF_RS14000	COG1278	Cold shock
YPDSF_RS14005	COG2197	response regulator
YPDSF_RS14030	COG5265	(ABC) transporter
YPDSF_RS14040	COG3718	enzyme involved in inositol metabolism
YPDSF_RS14050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_RS14055	COG0673	inositol 2-dehydrogenase activity
YPDSF_RS14060	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS14065	COG1129	ABC transporter
YPDSF_RS14100	COG2373	Large extracellular alpha-helical protein
YPDSF_RS14105	COG4953	penicillin-binding protein 1C
YPDSF_RS14110	COG3423	Transcriptional regulator
YPDSF_RS14160	COG2850	peptidyl-arginine hydroxylation
YPDSF_RS14165	COG3328	transposase activity
YPDSF_RS14180	COG1472	Belongs to the glycosyl hydrolase 3 family
YPDSF_RS14200	COG0656	L-ascorbic acid biosynthetic process
YPDSF_RS14205	COG0667	Aldo Keto reductase
YPDSF_RS14235	COG0671	phosphoesterase, PA-phosphatase related
YPDSF_RS14235	COG2453	phosphatase
YPDSF_RS14240	COG2267	carboxylic ester hydrolase activity
YPDSF_RS14250	COG4589	Belongs to the CDS family
YPDSF_RS14255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPDSF_RS14300	COG2501	S4 domain
YPDSF_RS14320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPDSF_RS14330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPDSF_RS14335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPDSF_RS14340	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPDSF_RS14345	COG4181	ATPase activity
YPDSF_RS14350	COG2755	lipolytic protein G-D-S-L family
YPDSF_RS14355	COG0300	oxidoreductase activity
YPDSF_RS14360	COG3118	belongs to the thioredoxin family
YPDSF_RS14365	COG0330	HflC and HflK could
YPDSF_RS14370	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPDSF_RS14375	COG0789	Transcriptional regulator
YPDSF_RS14380	COG2217	Heavy metal translocating P-type atpase
YPDSF_RS14385	COG3735	TraB family
YPDSF_RS14390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPDSF_RS14405	COG0737	Belongs to the 5'-nucleotidase family
YPDSF_RS14410	COG0737	Belongs to the 5'-nucleotidase family
YPDSF_RS14415	COG0737	Belongs to the 5'-nucleotidase family
YPDSF_RS14425	COG4651	solute:proton antiporter activity
YPDSF_RS14425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPDSF_RS14430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_RS14435	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPDSF_RS14455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_RS14495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPDSF_RS14515	COG0543	2 iron, 2 sulfur cluster binding
YPDSF_RS14515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPDSF_RS14545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPDSF_RS14570	COG1196	nuclear chromosome segregation
YPDSF_RS14570	COG3264	Mechanosensitive ion channel
YPDSF_RS14575	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPDSF_RS14580	COG1309	transcriptional regulator
YPDSF_RS14585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_RS14590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPDSF_RS14600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPDSF_RS14620	COG3695	enzyme binding
YPDSF_RS14625	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPDSF_RS14630	COG1946	Acyl-CoA thioesterase
YPDSF_RS14635	COG0004	ammonium transporteR
YPDSF_RS14640	COG0347	Belongs to the P(II) protein family
YPDSF_RS14645	COG1132	(ABC) transporter
YPDSF_RS14650	COG1132	(ABC) transporter
YPDSF_RS14655	COG1522	sequence-specific DNA binding
YPDSF_RS14670	COG4533	DNA binding
YPDSF_RS14680	COG0824	Thioesterase
YPDSF_RS14685	COG1555	photosystem II stabilization
YPDSF_RS14690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPDSF_RS14705	COG0776	regulation of translation
YPDSF_RS14710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPDSF_RS14735	COG0271	Belongs to the BolA IbaG family
YPDSF_RS14740	COG3056	Lipoprotein
YPDSF_RS14745	COG2223	nitrite transmembrane transporter activity
YPDSF_RS14755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPDSF_RS14760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPDSF_RS14765	COG1845	cytochrome c oxidase, subunit III
YPDSF_RS14770	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPDSF_RS14780	COG2814	Major facilitator Superfamily
YPDSF_RS14790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPDSF_RS14795	COG0693	protein deglycase activity
YPDSF_RS14815	COG0142	geranyltranstransferase activity
YPDSF_RS14830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPDSF_RS14835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPDSF_RS14850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPDSF_RS14850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPDSF_RS14875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPDSF_RS14880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPDSF_RS14885	COG1862	Preprotein translocase
YPDSF_RS14905	COG0450	alkyl hydroperoxide reductase
YPDSF_RS14925	COG0366	Alpha amylase catalytic
YPDSF_RS14945	COG5002	protein histidine kinase activity
YPDSF_RS14950	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS14960	COG0420	3'-5' exonuclease activity
YPDSF_RS14965	COG0419	ATPase involved in DNA repair
YPDSF_RS14970	COG1940	carbohydrate kinase activity
YPDSF_RS15005	COG2226	methyltransferase
YPDSF_RS15065	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPDSF_RS15085	COG1477	protein flavinylation
YPDSF_RS15105	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPDSF_RS15110	COG1805	sodium ion transport
YPDSF_RS15120	COG3034	peptidoglycan biosynthetic process
YPDSF_RS15125	COG0121	glutamine amidotransferase
YPDSF_RS15135	COG1960	acyl-CoA dehydrogenase activity
YPDSF_RS15150	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPDSF_RS15190	COG0436	Aminotransferase
YPDSF_RS15205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPDSF_RS15220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPDSF_RS15230	COG0765	amino acid transport
YPDSF_RS15270	COG2814	Major facilitator Superfamily
YPDSF_RS15275	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPDSF_RS15285	COG1846	Transcriptional regulator
YPDSF_RS15290	COG1566	PFAM secretion protein HlyD family protein
YPDSF_RS15295	COG2814	Major facilitator Superfamily
YPDSF_RS15300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPDSF_RS15305	COG3118	belongs to the thioredoxin family
YPDSF_RS15310	COG3148	PFAM DTW domain containing protein
YPDSF_RS15315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPDSF_RS15315	COG1042	CoA-binding domain protein
YPDSF_RS15315	COG0045	succinate-CoA ligase (ADP-forming) activity
YPDSF_RS15320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPDSF_RS15325	COG5544	Lipoprotein
YPDSF_RS15360	COG0542	response to heat
YPDSF_RS15370	COG0564	pseudouridine synthase activity
YPDSF_RS15375	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPDSF_RS15380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPDSF_RS15395	COG1605	Chorismate mutase
YPDSF_RS15395	COG0077	Prephenate dehydratase
YPDSF_RS15400	COG1605	Chorismate mutase
YPDSF_RS15400	COG0287	Prephenate dehydrogenase
YPDSF_RS15405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPDSF_RS15450	COG1459	type II secretion system
YPDSF_RS15455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPDSF_RS15460	COG4969	Belongs to the N-Me-Phe pilin family
YPDSF_RS15470	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPDSF_RS15475	COG3725	Membrane protein required for beta-lactamase induction
YPDSF_RS15480	COG1113	amino acid transport
YPDSF_RS15485	COG2186	Transcriptional regulator
YPDSF_RS15490	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPDSF_RS15495	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPDSF_RS15500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPDSF_RS15515	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPDSF_RS15525	COG0697	spore germination
YPDSF_RS15545	COG2132	Multicopper oxidase
YPDSF_RS15550	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPDSF_RS15555	COG0288	reversible hydration of carbon dioxide
YPDSF_RS15560	COG1131	(ABC) transporter
YPDSF_RS15565	COG0842	Transport permease protein
YPDSF_RS15590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPDSF_RS15595	COG0617	tRNA 3'-terminal CCA addition
YPDSF_RS15600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YPDSF_RS15615	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPDSF_RS15620	COG1643	Atp-dependent helicase
YPDSF_RS15625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPDSF_RS15635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPDSF_RS15640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_RS15660	COG2860	membrane
YPDSF_RS15680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPDSF_RS15685	COG2205	protein histidine kinase activity
YPDSF_RS15685	COG3437	response regulator, receiver
YPDSF_RS15685	COG3850	Histidine kinase
YPDSF_RS15685	COG4999	Histidine kinase
YPDSF_RS15690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPDSF_RS15700	COG3956	TIGRFAM MazG family protein
YPDSF_RS15720	COG0602	queuosine metabolic process
YPDSF_RS15725	COG0720	synthase
YPDSF_RS15775	COG0529	Catalyzes the synthesis of activated sulfate
YPDSF_RS15815	COG1388	LysM domain
YPDSF_RS15815	COG4942	peptidase
YPDSF_RS15820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPDSF_RS15835	COG0698	ribose 5-phosphate isomerase
YPDSF_RS15840	COG1063	alcohol dehydrogenase
YPDSF_RS15845	COG1028	Short-chain dehydrogenase reductase Sdr
YPDSF_RS15850	COG2376	Dihydroxyacetone kinase
YPDSF_RS15865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPDSF_RS15885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_RS15890	COG1858	cytochrome C peroxidase
YPDSF_RS15900	COG4771	TonB-dependent receptor
YPDSF_RS15925	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPDSF_RS15925	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPDSF_RS15930	COG1070	Carbohydrate kinase
YPDSF_RS15935	COG3623	hexulose-6-phosphate isomerase
YPDSF_RS15940	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS15945	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS15950	COG1129	ABC transporter
YPDSF_RS15960	COG1349	DNA-binding transcription factor activity
YPDSF_RS15965	COG0235	Class ii aldolase
YPDSF_RS15970	COG0243	molybdopterin cofactor binding
YPDSF_RS15975	COG0437	4 iron, 4 sulfur cluster binding
YPDSF_RS15980	COG3302	dmso reductase anchor subunit
YPDSF_RS15985	COG3381	protein complex oligomerization
YPDSF_RS15990	COG3038	cytochrome b561
YPDSF_RS15995	COG3783	Cytochrome b(562)
YPDSF_RS16005	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_RS16015	COG1129	ABC transporter
YPDSF_RS16020	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS16025	COG3959	Transketolase, thiamine diphosphate binding domain
YPDSF_RS16030	COG3958	Transketolase
YPDSF_RS16035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPDSF_RS16075	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPDSF_RS16095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPDSF_RS16100	COG1238	metal cluster binding
YPDSF_RS16105	COG2918	glutathione biosynthetic process
YPDSF_RS16115	COG4536	flavin adenine dinucleotide binding
YPDSF_RS16120	COG4137	Cytochrome C assembly protein
YPDSF_RS16125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPDSF_RS16150	COG3137	Salt-induced outer membrane protein
YPDSF_RS16160	COG3279	Response regulator of the LytR AlgR family
YPDSF_RS16165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPDSF_RS16180	COG0494	nUDIX hydrolase
YPDSF_RS16205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPDSF_RS16210	COG0849	cell division
YPDSF_RS16215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPDSF_RS16235	COG0772	Belongs to the SEDS family
YPDSF_RS16250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPDSF_RS16255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPDSF_RS16260	COG0768	penicillin binding
YPDSF_RS16265	COG3116	cell division
YPDSF_RS16290	COG1609	Transcriptional regulator
YPDSF_RS16310	COG0028	Belongs to the TPP enzyme family
YPDSF_RS16320	COG3328	transposase activity
YPDSF_RS16325	COG1022	Amp-dependent synthetase and ligase
YPDSF_RS16345	COG0473	3-isopropylmalate dehydrogenase activity
YPDSF_RS16360	COG2814	Major facilitator Superfamily
YPDSF_RS16380	COG4143	(ABC) transporter
YPDSF_RS16385	COG1178	ABC-type Fe3 transport system permease component
YPDSF_RS16390	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
YPDSF_RS16395	COG0586	Pfam SNARE associated Golgi protein
YPDSF_RS16400	COG0417	DNA replication proofreading
YPDSF_RS16420	COG2885	chlorophyll binding
YPDSF_RS16420	COG3047	cAMP biosynthetic process
YPDSF_RS16505	COG0564	pseudouridine synthase activity
YPDSF_RS16510	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YPDSF_RS16560	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPDSF_RS16570	COG2966	Psort location CytoplasmicMembrane, score
YPDSF_RS16575	COG1280	lysine exporter protein (LysE YggA)
YPDSF_RS16580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPDSF_RS16605	COG1047	Peptidyl-prolyl cis-trans
YPDSF_RS16620	COG0196	riboflavin kinase activity
YPDSF_RS16635	COG0583	DNA-binding transcription factor activity
YPDSF_RS16655	COG1584	GPR1 FUN34 yaaH family protein
YPDSF_RS16670	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPDSF_RS16700	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS16705	COG3045	CreA protein
YPDSF_RS16710	COG3708	Transcriptional regulator
YPDSF_RS16710	COG2207	Transcriptional regulator
YPDSF_RS16725	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPDSF_RS16730	COG0741	lytic transglycosylase activity
YPDSF_RS16745	COG2199	diguanylate cyclase activity
YPDSF_RS16750	COG2885	chlorophyll binding
YPDSF_RS16755	COG0488	(ABC) transporter
YPDSF_RS16775	COG0560	Phosphoserine phosphatase
YPDSF_RS16780	COG3726	membrane protein affecting hemolysin expression
YPDSF_RS16810	COG0084	hydrolase, TatD family'
YPDSF_RS16815	COG4667	esterase of the alpha-beta hydrolase superfamily
YPDSF_RS16825	COG2823	Periplasmic or secreted lipoprotein
YPDSF_RS16835	COG0456	acetyltransferase
YPDSF_RS16840	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPDSF_RS16885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPDSF_RS16890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPDSF_RS16910	COG0859	PFAM glycosyl transferase family 9
YPDSF_RS16920	COG2390	Transcriptional regulator
YPDSF_RS16965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPDSF_RS16965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_RS16965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPDSF_RS16970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_RS16975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_RS16980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPDSF_RS16985	COG2207	Transcriptional regulator
YPDSF_RS16995	COG4269	membrane
YPDSF_RS17050	COG2963	transposase activity
YPDSF_RS17065	COG1401	restriction endodeoxyribonuclease activity
YPDSF_RS17090	COG0582	viral genome integration into host DNA
YPDSF_RS17100	COG0795	lipopolysaccharide-transporting ATPase activity
YPDSF_RS17105	COG0795	lipopolysaccharide-transporting ATPase activity
YPDSF_RS17115	COG2927	DNA polymerase III (CHI subunit)
YPDSF_RS17120	COG0525	valine-tRNA ligase activity
YPDSF_RS17130	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPDSF_RS17140	COG2731	YhcH YjgK YiaL family protein
YPDSF_RS17150	COG0601	transmembrane transport
YPDSF_RS17155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPDSF_RS17160	COG0444	Belongs to the ABC transporter superfamily
YPDSF_RS17165	COG4608	Belongs to the ABC transporter superfamily
YPDSF_RS17180	COG2188	Transcriptional regulator
YPDSF_RS17185	COG3624	Phosphonate C-P lyase system protein PhnG
YPDSF_RS17190	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPDSF_RS17195	COG3626	phosphonate metabolism
YPDSF_RS17200	COG3627	carbon phosphorus lyase activity
YPDSF_RS17205	COG4107	phosphonate C-P lyase system protein PhnK
YPDSF_RS17210	COG4778	phosphonate C-P lyase system protein PhnL
YPDSF_RS17215	COG3454	Phosphonate metabolism
YPDSF_RS17220	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPDSF_RS17225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPDSF_RS17230	COG0702	epimerase
YPDSF_RS17245	COG3842	ATPase activity
YPDSF_RS17250	COG0395	ABC-type sugar transport system, permease component
YPDSF_RS17255	COG1175	transmembrane transport
YPDSF_RS17260	COG1653	transport
YPDSF_RS17280	COG3153	acetyltransferase
YPDSF_RS17285	COG3154	lipid carrier protein
YPDSF_RS17295	COG0826	peptidase U32
YPDSF_RS17300	COG0826	peptidase U32
YPDSF_RS17310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPDSF_RS17320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPDSF_RS17340	COG0513	Belongs to the DEAD box helicase family
YPDSF_RS17360	COG2801	Transposase and inactivated derivatives
YPDSF_RS17380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPDSF_RS17385	COG0058	SHG alpha-glucan phosphorylase activity
YPDSF_RS17410	COG3275	phosphorelay sensor kinase activity
YPDSF_RS17440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPDSF_RS17445	COG2095	MarC family integral membrane protein
YPDSF_RS17465	COG3265	gluconokinase activity
YPDSF_RS17470	COG2610	gluconate transmembrane transporter activity
YPDSF_RS17475	COG1609	Transcriptional regulator
YPDSF_RS17480	COG1741	Belongs to the pirin family
YPDSF_RS17500	COG0191	fructose-bisphosphate aldolase activity
YPDSF_RS17515	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS17530	COG2081	HI0933 family
YPDSF_RS17535	COG0306	phosphate transporter
YPDSF_RS17555	COG0589	response to stress
YPDSF_RS17575	COG0339	signal peptide processing
YPDSF_RS17580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPDSF_RS17585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPDSF_RS17590	COG3835	regulator
YPDSF_RS17595	COG2610	gluconate transmembrane transporter activity
YPDSF_RS17600	COG1929	Belongs to the glycerate kinase type-1 family
YPDSF_RS17625	COG1295	ribonuclease BN
YPDSF_RS17630	COG2134	cdp-diacylglycerol pyrophosphatase
YPDSF_RS17635	COG2982	Protein involved in outer membrane biogenesis
YPDSF_RS17640	COG2200	EAL domain
YPDSF_RS17645	COG1942	4-Oxalocrotonate Tautomerase
YPDSF_RS17650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPDSF_RS17655	COG0612	Peptidase, M16
YPDSF_RS17675	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPDSF_RS17680	COG2199	diguanylate cyclase activity
YPDSF_RS17680	COG2200	EAL domain
YPDSF_RS17685	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPDSF_RS17690	COG4608	Belongs to the ABC transporter superfamily
YPDSF_RS17695	COG0444	Belongs to the ABC transporter superfamily
YPDSF_RS17705	COG0601	transmembrane transport
YPDSF_RS17710	COG0747	negative chemotaxis
YPDSF_RS17720	COG2831	hemolysin activation secretion protein
YPDSF_RS17735	COG2271	Major facilitator Superfamily
YPDSF_RS17740	COG3851	Histidine kinase
YPDSF_RS17745	COG2197	response regulator
YPDSF_RS17750	COG2194	sulfuric ester hydrolase activity
YPDSF_RS17780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YPDSF_RS17815	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPDSF_RS17820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPDSF_RS17825	COG1739	Uncharacterized protein family UPF0029
YPDSF_RS17850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YPDSF_RS17870	COG0805	protein transport
YPDSF_RS17880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPDSF_RS17900	COG1322	Protein conserved in bacteria
YPDSF_RS17905	COG0586	Pfam SNARE associated Golgi protein
YPDSF_RS17910	COG1966	Carbon starvation protein
YPDSF_RS17925	COG0412	Dienelactone hydrolase
YPDSF_RS17935	COG0583	DNA-binding transcription factor activity
YPDSF_RS17940	COG0697	spore germination
YPDSF_RS17945	COG0679	Auxin Efflux Carrier
YPDSF_RS17950	COG0584	glycerophosphoryl diester phosphodiesterase
YPDSF_RS18010	COG0410	ABC transporter
YPDSF_RS18020	COG4177	L-phenylalanine transmembrane transporter activity
YPDSF_RS18030	COG0683	leucine binding
YPDSF_RS18055	COG2177	Part of the ABC transporter FtsEX involved in
YPDSF_RS18060	COG2884	Cell division ATP-binding protein ftsE
YPDSF_RS18065	COG0552	protein localization to endoplasmic reticulum
YPDSF_RS18065	COG0552	protein localization to endoplasmic reticulum
YPDSF_RS18075	COG0742	ribosomal rna small subunit methyltransferase
YPDSF_RS18080	COG3776	membrane
YPDSF_RS18095	COG3714	YhhN family
YPDSF_RS18110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPDSF_RS18120	COG0247	lactate metabolic process
YPDSF_RS18130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPDSF_RS18140	COG0584	glycerophosphoryl diester phosphodiesterase
YPDSF_RS18150	COG0561	phosphatase activity
YPDSF_RS18155	COG2267	carboxylic ester hydrolase activity
YPDSF_RS18160	COG1280	lysine exporter protein (LysE YggA)
YPDSF_RS18165	COG1280	lysine exporter protein (LysE YggA)
YPDSF_RS18170	COG0514	ATP-dependent DNA helicase (RecQ)
YPDSF_RS18175	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPDSF_RS18180	COG2050	protein possibly involved in aromatic compounds catabolism
YPDSF_RS18195	COG5564	TIM-barrel signal transduction protein
YPDSF_RS18200	COG5441	Belongs to the UPF0261 family
YPDSF_RS18210	COG0210	DNA helicase
YPDSF_RS18215	COG1011	Hydrolase
YPDSF_RS18220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPDSF_RS18225	COG3159	Protein conserved in bacteria
YPDSF_RS18245	COG3072	Adenylate cyclase
YPDSF_RS18255	COG1587	Uroporphyrinogen-III synthase
YPDSF_RS18260	COG2959	enzyme of heme biosynthesis
YPDSF_RS18265	COG3071	HemY protein
YPDSF_RS18295	COG1113	amino acid transport
YPDSF_RS18315	COG2244	polysaccharide biosynthetic process
YPDSF_RS18320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPDSF_RS18325	COG0456	acetyltransferase
YPDSF_RS18330	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPDSF_RS18335	COG1088	dTDP-glucose 4,6-dehydratase activity
YPDSF_RS18340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPDSF_RS18345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPDSF_RS18350	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPDSF_RS18355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPDSF_RS18360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPDSF_RS18365	COG3118	belongs to the thioredoxin family
YPDSF_RS18390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPDSF_RS18410	COG3121	Chaperone
YPDSF_RS18425	COG3121	Chaperone
YPDSF_RS18465	COG0583	DNA-binding transcription factor activity
YPDSF_RS18510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPDSF_RS18515	COG3978	acetolactate synthase activity
YPDSF_RS18530	COG3085	chromosome segregation
YPDSF_RS18540	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS18545	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPDSF_RS18550	COG1129	ABC transporter
YPDSF_RS18555	COG1879	ABC-type sugar transport system periplasmic component
YPDSF_RS18635	COG0678	peroxiredoxin activity
YPDSF_RS18635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPDSF_RS18640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPDSF_RS18665	COG1629	transport
YPDSF_RS18685	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YPDSF_RS18705	COG2801	Transposase and inactivated derivatives
YPDSF_RS18730	COG0195	Participates in both transcription termination and antitermination
YPDSF_RS18750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPDSF_RS18760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPDSF_RS18775	COG1534	Rna-binding protein
YPDSF_RS18785	COG2027	D-alanyl-D-alanine carboxypeptidase
YPDSF_RS18790	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS18795	COG0642	Histidine kinase
YPDSF_RS18805	COG0697	spore germination
YPDSF_RS18820	COG0142	geranyltranstransferase activity
YPDSF_RS18830	COG3423	Transcriptional regulator
YPDSF_RS18855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPDSF_RS18865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPDSF_RS18870	COG2105	PFAM AIG2 family protein
YPDSF_RS18875	COG2911	Protein conserved in bacteria
YPDSF_RS18880	COG0729	surface antigen
YPDSF_RS18890	COG1253	flavin adenine dinucleotide binding
YPDSF_RS18900	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPDSF_RS18910	COG0737	Belongs to the 5'-nucleotidase family
YPDSF_RS18920	COG0545	Peptidyl-prolyl cis-trans isomerase
YPDSF_RS18925	COG3061	Opacity-associated protein A
YPDSF_RS18950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPDSF_RS18970	COG1073	alpha beta
YPDSF_RS18985	COG3650	response to hydrogen peroxide
YPDSF_RS18990	COG1960	acyl-CoA dehydrogenase activity
YPDSF_RS18995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPDSF_RS19015	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPDSF_RS19020	COG0330	HflC and HflK could
YPDSF_RS19025	COG0330	HflC and HflK could
YPDSF_RS19030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPDSF_RS19050	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPDSF_RS19055	COG0802	atpase or kinase
YPDSF_RS19060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPDSF_RS19060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPDSF_RS19065	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPDSF_RS19080	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YPDSF_RS19100	COG3264	Mechanosensitive ion channel
YPDSF_RS19100	COG1511	domain protein
YPDSF_RS19115	COG1053	succinate dehydrogenase
YPDSF_RS19120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPDSF_RS19130	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPDSF_RS19175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPDSF_RS19190	COG3383	formate dehydrogenase (NAD+) activity
YPDSF_RS19195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_RS19200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPDSF_RS19200	COG0493	'glutamate synthase
YPDSF_RS19205	COG1309	transcriptional regulator
YPDSF_RS19275	COG1454	alcohol dehydrogenase
YPDSF_RS19285	COG0629	single-stranded DNA binding
YPDSF_RS19290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPDSF_RS19295	COG2315	Protein conserved in bacteria
YPDSF_RS19300	COG1448	Aminotransferase
YPDSF_RS19325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPDSF_RS19330	COG0735	belongs to the Fur family
YPDSF_RS19340	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPDSF_RS19385	COG3121	Chaperone
YPDSF_RS19445	COG1358	cellular component organization or biogenesis
YPDSF_RS19470	COG3721	Heme iron utilization protein
YPDSF_RS19475	COG0702	epimerase
YPDSF_RS19485	COG4771	TonB-dependent receptor
YPDSF_RS19490	COG3720	iron ion transport
YPDSF_RS19495	COG4558	Periplasmic binding protein
YPDSF_RS19500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPDSF_RS19510	COG0626	cystathionine gamma-synthase activity
YPDSF_RS19515	COG0814	amino acid
YPDSF_RS19520	COG0583	DNA-binding transcription factor activity
YPDSF_RS19525	COG0425	Belongs to the sulfur carrier protein TusA family
YPDSF_RS19530	COG2391	methyltransferase activity
YPDSF_RS19640	COG1301	dicarboxylic acid transport
YPDSF_RS19650	COG3162	membrane
YPDSF_RS19675	COG2801	Transposase and inactivated derivatives
YPDSF_RS19715	COG0151	Belongs to the GarS family
YPDSF_RS19735	COG1515	deoxyribonuclease V activity
YPDSF_RS19775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPDSF_RS19830	COG0250	Participates in transcription elongation, termination and antitermination
YPDSF_RS19890	COG2986	histidine ammonia-lyase
YPDSF_RS19920	COG4607	ABC-type enterochelin transport system periplasmic component
YPDSF_RS19930	COG4605	iron ion homeostasis
YPDSF_RS19935	COG4604	ABC transporter, ATP-binding protein
YPDSF_RS19975	COG0582	viral genome integration into host DNA
YPDSF_RS19980	COG1609	Transcriptional regulator
YPDSF_RS19980	COG2207	Transcriptional regulator
YPDSF_RS19985	COG4214	carbohydrate transport
YPDSF_RS19995	COG4213	ABC transporter substrate-binding protein
YPDSF_RS20005	COG1070	Carbohydrate kinase
YPDSF_RS20015	COG3121	Chaperone
YPDSF_RS20035	COG3274	enterobacterial common antigen metabolic process
YPDSF_RS20050	COG2801	Transposase and inactivated derivatives
YPDSF_RS20060	COG0527	aspartate kinase activity
YPDSF_RS20060	COG0460	homoserine dehydrogenase
YPDSF_RS20065	COG0626	cystathionine gamma-synthase activity
YPDSF_RS20080	COG4682	membrane
YPDSF_RS20090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPDSF_RS20100	COG1609	Transcriptional regulator
YPDSF_RS20105	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPDSF_RS20120	COG1575	Belongs to the MenA family. Type 1 subfamily
YPDSF_RS20170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPDSF_RS20175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPDSF_RS20180	COG1494	fructose-1,6-bisphosphatase
YPDSF_RS20190	COG3152	Membrane
YPDSF_RS20205	COG0583	DNA-binding transcription factor activity
YPDSF_RS20210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPDSF_RS20215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPDSF_RS20230	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPDSF_RS20250	COG3678	ATP-independent chaperone mediated protein folding
YPDSF_RS20255	COG0745	RESPONSE REGULATOR receiver
YPDSF_RS20260	COG2205	protein histidine kinase activity
YPDSF_RS20265	COG2169	Transcriptional regulator
YPDSF_RS20265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPDSF_RS20270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPDSF_RS20275	COG1045	serine acetyltransferase
YPDSF_RS20295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPDSF_RS20300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPDSF_RS20310	COG4942	peptidase
YPDSF_RS20325	COG0156	8-amino-7-oxononanoate synthase activity
YPDSF_RS20335	COG0859	PFAM glycosyl transferase family 9
YPDSF_RS20340	COG0859	PFAM glycosyl transferase family 9
YPDSF_RS20345	COG1519	Transferase
YPDSF_RS20380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPDSF_RS20405	COG1561	YicC-like family, N-terminal region
YPDSF_RS20410	COG2860	membrane
YPDSF_RS20430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPDSF_RS20435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPDSF_RS20440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPDSF_RS20445	COG0786	glutamate:sodium symporter activity
YPDSF_RS20450	COG2233	PERMEase
YPDSF_RS20455	COG2982	Protein involved in outer membrane biogenesis
YPDSF_RS20460	COG0456	acetyltransferase
YPDSF_RS20485	COG1011	Hydrolase
YPDSF_RS20500	COG0174	glutamine synthetase
YPDSF_RS20505	COG3852	Histidine kinase
YPDSF_RS20515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPDSF_RS20530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPDSF_RS20530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPDSF_RS20535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPDSF_RS20540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPDSF_RS20545	COG3084	Protein conserved in bacteria
YPDSF_RS20555	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPDSF_RS20560	COG3328	transposase activity
YPDSF_RS20590	COG2186	Transcriptional regulator
YPDSF_RS20595	COG0477	Major facilitator Superfamily
YPDSF_RS20635	COG1522	sequence-specific DNA binding
YPDSF_RS20640	COG0716	FMN binding
YPDSF_RS20655	COG3312	ion transport
YPDSF_RS20710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPDSF_RS20715	COG0573	inorganic phosphate transmembrane transporter activity
YPDSF_RS20720	COG0581	inorganic phosphate transmembrane transporter activity
YPDSF_RS20730	COG0704	Plays a role in the regulation of phosphate uptake
YPDSF_RS20740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPDSF_RS20745	COG0765	amino acid transport
YPDSF_RS20750	COG0765	amino acid transport
YPDSF_RS20755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPDSF_RS20760	COG2252	PERMEase
YPDSF_RS20785	COG0706	membrane insertase activity
YPDSF_RS20795	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPDSF_RS20905	COG2423	ornithine cyclodeaminase activity
YPDSF_RS21390	COG0366	Alpha amylase catalytic
YPDSF_RS21885	COG2116	formate transmembrane transporter activity
YPDSF_RS21985	COG0429	hydrolase of the alpha beta-hydrolase fold