locus-tag	class	description
GCK71_RS00010	COG0592	DNA-directed DNA polymerase activity
GCK71_RS00020	COG0187	DNA topoisomerase II activity
GCK71_RS00025	COG0561	phosphatase activity
GCK71_RS00045	COG2423	ornithine cyclodeaminase activity
GCK71_RS00050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCK71_RS00065	COG5645	(Lipo)protein
GCK71_RS00085	COG3977	Valine--pyruvate aminotransferase
GCK71_RS00105	COG0366	Alpha amylase catalytic
GCK71_RS00125	COG2885	chlorophyll binding
GCK71_RS00135	COG2818	Glycosylase
GCK71_RS00160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK71_RS00160	COG2213	PTS system mannitol-specific
GCK71_RS00170	COG3722	fumarate hydratase activity
GCK71_RS00195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCK71_RS00210	COG0437	4 iron, 4 sulfur cluster binding
GCK71_RS00215	COG2864	formate dehydrogenase
GCK71_RS00230	COG3276	selenocysteine insertion sequence binding
GCK71_RS00270	COG1349	DNA-binding transcription factor activity
GCK71_RS00290	COG0058	SHG alpha-glucan phosphorylase activity
GCK71_RS00295	COG0058	SHG alpha-glucan phosphorylase activity
GCK71_RS00300	COG1640	4-alpha-glucanotransferase
GCK71_RS00335	COG1918	ferrous iron import across plasma membrane
GCK71_RS00340	COG2183	response to ionizing radiation
GCK71_RS00345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK71_RS00370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GCK71_RS00375	COG1011	Hydrolase
GCK71_RS00385	COG0494	nUDIX hydrolase
GCK71_RS00390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GCK71_RS00420	COG4796	Type ii and iii secretion system protein
GCK71_RS00445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GCK71_RS00450	COG0546	phosphoglycolate phosphatase activity
GCK71_RS00455	COG0180	Tryptophanyl-tRNA synthetase
GCK71_RS00475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCK71_RS00480	COG0402	S-adenosylhomocysteine deaminase activity
GCK71_RS00500	COG1486	melibiose metabolic process
GCK71_RS00505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK71_RS00510	COG0433	COG0433 Predicted ATPase
GCK71_RS00525	COG1289	transmembrane transporter activity
GCK71_RS00535	COG1765	OsmC-like protein
GCK71_RS00545	COG3954	Phosphoribulokinase
GCK71_RS00555	COG0429	hydrolase of the alpha beta-hydrolase fold
GCK71_RS00565	COG4521	taurine ABC transporter
GCK71_RS00575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK71_RS00580	COG2175	clavaminate synthase activity
GCK71_RS00590	COG1216	Glycosyl transferase, family 2
GCK71_RS00610	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GCK71_RS00615	COG1047	Peptidyl-prolyl cis-trans
GCK71_RS00630	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK71_RS00635	COG2964	Protein conserved in bacteria
GCK71_RS00655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GCK71_RS00660	COG0049	tRNA binding
GCK71_RS00695	COG0051	transcription antitermination factor activity, RNA binding
GCK71_RS00710	COG0089	rRNA binding
GCK71_RS00720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GCK71_RS00730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GCK71_RS00735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GCK71_RS00745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GCK71_RS00750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GCK71_RS00790	COG1841	ribosomal large subunit assembly
GCK71_RS00800	COG0201	protein transport
GCK71_RS00805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK71_RS00820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GCK71_RS00835	COG0789	Transcriptional regulator
GCK71_RS00840	COG3036	rescue of stalled ribosome
GCK71_RS00870	COG0758	DNA mediated transformation
GCK71_RS00880	COG0551	DNA topoisomerase type I activity
GCK71_RS00895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GCK71_RS00910	COG0456	acetyltransferase
GCK71_RS00915	COG2982	Protein involved in outer membrane biogenesis
GCK71_RS00920	COG2233	PERMEase
GCK71_RS00925	COG0786	glutamate:sodium symporter activity
GCK71_RS00935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK71_RS00940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK71_RS00945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK71_RS00965	COG2860	membrane
GCK71_RS00970	COG1561	YicC-like family, N-terminal region
GCK71_RS00995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCK71_RS01035	COG1519	Transferase
GCK71_RS01040	COG0859	PFAM glycosyl transferase family 9
GCK71_RS01045	COG0859	PFAM glycosyl transferase family 9
GCK71_RS01055	COG0156	8-amino-7-oxononanoate synthase activity
GCK71_RS01070	COG4942	peptidase
GCK71_RS01080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCK71_RS01085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK71_RS01105	COG1045	serine acetyltransferase
GCK71_RS01110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GCK71_RS01115	COG2169	Transcriptional regulator
GCK71_RS01115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK71_RS01120	COG2205	protein histidine kinase activity
GCK71_RS01125	COG0745	RESPONSE REGULATOR receiver
GCK71_RS01130	COG3678	ATP-independent chaperone mediated protein folding
GCK71_RS01160	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GCK71_RS01170	COG0471	metal ion transport
GCK71_RS01175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCK71_RS01180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCK71_RS01185	COG0583	DNA-binding transcription factor activity
GCK71_RS01200	COG3152	Membrane
GCK71_RS01210	COG1494	fructose-1,6-bisphosphatase
GCK71_RS01215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK71_RS01220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GCK71_RS01280	COG1575	Belongs to the MenA family. Type 1 subfamily
GCK71_RS01295	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK71_RS01310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCK71_RS01320	COG4682	membrane
GCK71_RS01335	COG0527	aspartate kinase activity
GCK71_RS01335	COG0460	homoserine dehydrogenase
GCK71_RS01375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCK71_RS01390	COG1629	transport
GCK71_RS01415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK71_RS01420	COG0678	peroxiredoxin activity
GCK71_RS01420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK71_RS01500	COG1879	ABC-type sugar transport system periplasmic component
GCK71_RS01505	COG1129	ABC transporter
GCK71_RS01510	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS01515	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS01525	COG3085	chromosome segregation
GCK71_RS01550	COG3978	acetolactate synthase activity
GCK71_RS01555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK71_RS01595	COG0583	DNA-binding transcription factor activity
GCK71_RS01635	COG3121	Chaperone
GCK71_RS01650	COG3121	Chaperone
GCK71_RS01665	COG3328	transposase activity
GCK71_RS01675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK71_RS01700	COG3118	belongs to the thioredoxin family
GCK71_RS01705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GCK71_RS01710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCK71_RS01715	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK71_RS01720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GCK71_RS01725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GCK71_RS01730	COG1088	dTDP-glucose 4,6-dehydratase activity
GCK71_RS01735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GCK71_RS01740	COG0456	acetyltransferase
GCK71_RS01745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GCK71_RS01750	COG2244	polysaccharide biosynthetic process
GCK71_RS01770	COG1113	amino acid transport
GCK71_RS01805	COG3071	HemY protein
GCK71_RS01810	COG2959	enzyme of heme biosynthesis
GCK71_RS01815	COG1587	Uroporphyrinogen-III synthase
GCK71_RS01830	COG3072	Adenylate cyclase
GCK71_RS01850	COG3159	Protein conserved in bacteria
GCK71_RS01855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GCK71_RS01860	COG1011	Hydrolase
GCK71_RS01865	COG0210	DNA helicase
GCK71_RS01875	COG5441	Belongs to the UPF0261 family
GCK71_RS01880	COG5564	TIM-barrel signal transduction protein
GCK71_RS01895	COG2050	protein possibly involved in aromatic compounds catabolism
GCK71_RS01900	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GCK71_RS01905	COG0514	ATP-dependent DNA helicase (RecQ)
GCK71_RS01910	COG1280	lysine exporter protein (LysE YggA)
GCK71_RS01915	COG1280	lysine exporter protein (LysE YggA)
GCK71_RS01920	COG2267	carboxylic ester hydrolase activity
GCK71_RS01925	COG0561	phosphatase activity
GCK71_RS01935	COG0584	glycerophosphoryl diester phosphodiesterase
GCK71_RS01950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK71_RS01960	COG0247	lactate metabolic process
GCK71_RS01970	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GCK71_RS01985	COG3714	YhhN family
GCK71_RS02000	COG3776	membrane
GCK71_RS02005	COG0742	ribosomal rna small subunit methyltransferase
GCK71_RS02015	COG0552	protein localization to endoplasmic reticulum
GCK71_RS02015	COG0552	protein localization to endoplasmic reticulum
GCK71_RS02020	COG2884	Cell division ATP-binding protein ftsE
GCK71_RS02025	COG2177	Part of the ABC transporter FtsEX involved in
GCK71_RS02045	COG0683	leucine binding
GCK71_RS02055	COG4177	L-phenylalanine transmembrane transporter activity
GCK71_RS02065	COG0410	ABC transporter
GCK71_RS02125	COG0584	glycerophosphoryl diester phosphodiesterase
GCK71_RS02130	COG0679	Auxin Efflux Carrier
GCK71_RS02135	COG0697	spore germination
GCK71_RS02140	COG0583	DNA-binding transcription factor activity
GCK71_RS02150	COG0412	Dienelactone hydrolase
GCK71_RS02165	COG1966	Carbon starvation protein
GCK71_RS02170	COG0586	Pfam SNARE associated Golgi protein
GCK71_RS02175	COG1322	Protein conserved in bacteria
GCK71_RS02195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK71_RS02205	COG0805	protein transport
GCK71_RS02240	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GCK71_RS02265	COG1739	Uncharacterized protein family UPF0029
GCK71_RS02280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GCK71_RS02285	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GCK71_RS02320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GCK71_RS02380	COG0250	Participates in transcription elongation, termination and antitermination
GCK71_RS02440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCK71_RS02475	COG1515	deoxyribonuclease V activity
GCK71_RS02495	COG0151	Belongs to the GarS family
GCK71_RS02545	COG3328	transposase activity
GCK71_RS02550	COG1763	Mo-molybdopterin cofactor biosynthetic process
GCK71_RS02560	COG3084	Protein conserved in bacteria
GCK71_RS02565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCK71_RS02570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK71_RS02575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK71_RS02575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK71_RS02610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK71_RS02620	COG3852	Histidine kinase
GCK71_RS02625	COG0174	glutamine synthetase
GCK71_RS02635	COG1011	Hydrolase
GCK71_RS02660	COG1401	restriction endodeoxyribonuclease activity
GCK71_RS02720	COG4269	membrane
GCK71_RS02730	COG2207	Transcriptional regulator
GCK71_RS02735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK71_RS02740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK71_RS02745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK71_RS02750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK71_RS02750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK71_RS02750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK71_RS02800	COG1070	Carbohydrate kinase
GCK71_RS02805	COG0859	PFAM glycosyl transferase family 9
GCK71_RS02820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK71_RS02825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK71_RS02870	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GCK71_RS02875	COG0456	acetyltransferase
GCK71_RS02885	COG2823	Periplasmic or secreted lipoprotein
GCK71_RS02895	COG4667	esterase of the alpha-beta hydrolase superfamily
GCK71_RS02900	COG0084	hydrolase, TatD family'
GCK71_RS02905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK71_RS02930	COG3726	membrane protein affecting hemolysin expression
GCK71_RS02935	COG0560	Phosphoserine phosphatase
GCK71_RS02960	COG2885	chlorophyll binding
GCK71_RS02965	COG2199	diguanylate cyclase activity
GCK71_RS02980	COG0741	lytic transglycosylase activity
GCK71_RS02985	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GCK71_RS03000	COG2207	Transcriptional regulator
GCK71_RS03000	COG3708	Transcriptional regulator
GCK71_RS03010	COG3045	CreA protein
GCK71_RS03015	COG0745	RESPONSE REGULATOR receiver
GCK71_RS03055	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCK71_RS03070	COG1584	GPR1 FUN34 yaaH family protein
GCK71_RS03090	COG0583	DNA-binding transcription factor activity
GCK71_RS03110	COG0196	riboflavin kinase activity
GCK71_RS03125	COG1047	Peptidyl-prolyl cis-trans
GCK71_RS03145	COG0473	3-isopropylmalate dehydrogenase activity
GCK71_RS03160	COG2814	Major facilitator Superfamily
GCK71_RS03175	COG4143	(ABC) transporter
GCK71_RS03180	COG1178	ABC-type Fe3 transport system permease component
GCK71_RS03185	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GCK71_RS03190	COG0586	Pfam SNARE associated Golgi protein
GCK71_RS03195	COG0417	DNA replication proofreading
GCK71_RS03215	COG2885	chlorophyll binding
GCK71_RS03215	COG3047	cAMP biosynthetic process
GCK71_RS03300	COG0564	pseudouridine synthase activity
GCK71_RS03305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GCK71_RS03355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCK71_RS03365	COG2966	Psort location CytoplasmicMembrane, score
GCK71_RS03370	COG1280	lysine exporter protein (LysE YggA)
GCK71_RS03375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GCK71_RS03410	COG1022	Amp-dependent synthetase and ligase
GCK71_RS03420	COG0028	Belongs to the TPP enzyme family
GCK71_RS03440	COG1609	Transcriptional regulator
GCK71_RS03465	COG3116	cell division
GCK71_RS03470	COG0768	penicillin binding
GCK71_RS03475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GCK71_RS03480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GCK71_RS03495	COG0772	Belongs to the SEDS family
GCK71_RS03515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GCK71_RS03520	COG0849	cell division
GCK71_RS03525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GCK71_RS03555	COG0494	nUDIX hydrolase
GCK71_RS03575	COG2259	Doxx family
GCK71_RS03585	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GCK71_RS03590	COG4575	ribosome binding
GCK71_RS03610	COG0586	Pfam SNARE associated Golgi protein
GCK71_RS03625	COG2271	Major facilitator Superfamily
GCK71_RS03640	COG2721	sulfolactate sulfo-lyase activity
GCK71_RS03660	COG0673	inositol 2-dehydrogenase activity
GCK71_RS03665	COG1451	nucleotide metabolic process
GCK71_RS03680	COG0446	pyridine nucleotide-disulphide oxidoreductase
GCK71_RS03680	COG1902	pentaerythritol trinitrate reductase activity
GCK71_RS03685	COG3247	response to pH
GCK71_RS03705	COG4245	von Willebrand factor, type A
GCK71_RS03720	COG4245	von Willebrand factor, type A
GCK71_RS03725	COG2831	hemolysin activation secretion protein
GCK71_RS03730	COG3210	domain, Protein
GCK71_RS03755	COG3210	domain, Protein
GCK71_RS03760	COG3210	domain, Protein
GCK71_RS03780	COG3842	ATPase activity
GCK71_RS03785	COG3459	Glycosyltransferase 36 associated
GCK71_RS03790	COG1609	Transcriptional regulator
GCK71_RS03795	COG2182	Extracellular solute-binding protein
GCK71_RS03805	COG0395	ABC-type sugar transport system, permease component
GCK71_RS03825	COG1289	transmembrane transporter activity
GCK71_RS03850	COG0436	Aminotransferase
GCK71_RS03870	COG0251	oxidation-reduction process
GCK71_RS03945	COG0358	DNA primase activity
GCK71_RS03950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GCK71_RS03970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GCK71_RS03985	COG4991	sh3 domain protein
GCK71_RS03990	COG3025	triphosphatase activity
GCK71_RS04005	COG0531	amino acid
GCK71_RS04025	COG3384	dioxygenase
GCK71_RS04030	COG0754	glutathionylspermidine amidase activity
GCK71_RS04045	COG1538	Outer membrane efflux protein
GCK71_RS04050	COG0494	nUDIX hydrolase
GCK71_RS04055	COG3151	Protein conserved in bacteria
GCK71_RS04060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCK71_RS04065	COG3150	esterase
GCK71_RS04075	COG0583	DNA-binding transcription factor activity
GCK71_RS04080	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCK71_RS04090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GCK71_RS04105	COG2132	Multicopper oxidase
GCK71_RS04120	COG0656	L-ascorbic acid biosynthetic process
GCK71_RS04130	COG1979	alcohol dehydrogenase
GCK71_RS04135	COG2207	Transcriptional regulator
GCK71_RS04140	COG0586	Pfam SNARE associated Golgi protein
GCK71_RS04145	COG0626	cystathionine gamma-synthase activity
GCK71_RS04150	COG0811	peptide transport
GCK71_RS04155	COG0848	biopolymer transport protein
GCK71_RS04210	COG4964	Belongs to the GSP D family
GCK71_RS04215	COG4964	Belongs to the GSP D family
GCK71_RS04250	COG4592	Periplasmic binding protein
GCK71_RS04270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK71_RS04275	COG1684	flagellar biosynthetic protein fliR
GCK71_RS04280	COG1987	bacterial-type flagellum assembly
GCK71_RS04305	COG1677	Flagellar hook-basal body complex protein FliE
GCK71_RS04345	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GCK71_RS04350	COG1815	bacterial-type flagellum-dependent cell motility
GCK71_RS04355	COG1558	bacterial-type flagellum-dependent cell motility
GCK71_RS04360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCK71_RS04365	COG1749	Flagellar hook protein flgE
GCK71_RS04370	COG4787	bacterial-type flagellum-dependent cell motility
GCK71_RS04375	COG4786	Flagellar basal body rod
GCK71_RS04385	COG1706	bacterial-type flagellum-dependent cell motility
GCK71_RS04395	COG1256	bacterial-type flagellum assembly
GCK71_RS04415	COG3710	Transcriptional regulator
GCK71_RS04445	COG0513	Belongs to the DEAD box helicase family
GCK71_RS04470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCK71_RS04480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK71_RS04490	COG0826	peptidase U32
GCK71_RS04495	COG0826	peptidase U32
GCK71_RS04505	COG3154	lipid carrier protein
GCK71_RS04510	COG3153	acetyltransferase
GCK71_RS04530	COG1653	transport
GCK71_RS04535	COG1175	transmembrane transport
GCK71_RS04540	COG0395	ABC-type sugar transport system, permease component
GCK71_RS04545	COG3842	ATPase activity
GCK71_RS04560	COG0702	epimerase
GCK71_RS04565	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCK71_RS04570	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GCK71_RS04575	COG3454	Phosphonate metabolism
GCK71_RS04580	COG4778	phosphonate C-P lyase system protein PhnL
GCK71_RS04585	COG4107	phosphonate C-P lyase system protein PhnK
GCK71_RS04590	COG3627	carbon phosphorus lyase activity
GCK71_RS04595	COG3626	phosphonate metabolism
GCK71_RS04600	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GCK71_RS04605	COG3624	Phosphonate C-P lyase system protein PhnG
GCK71_RS04610	COG2188	Transcriptional regulator
GCK71_RS04625	COG4608	Belongs to the ABC transporter superfamily
GCK71_RS04630	COG0444	Belongs to the ABC transporter superfamily
GCK71_RS04635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK71_RS04640	COG0601	transmembrane transport
GCK71_RS04650	COG2731	YhcH YjgK YiaL family protein
GCK71_RS04660	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GCK71_RS04670	COG0525	valine-tRNA ligase activity
GCK71_RS04675	COG2927	DNA polymerase III (CHI subunit)
GCK71_RS04685	COG0795	lipopolysaccharide-transporting ATPase activity
GCK71_RS04690	COG0795	lipopolysaccharide-transporting ATPase activity
GCK71_RS04700	COG0582	viral genome integration into host DNA
GCK71_RS04755	COG1459	type II secretion system
GCK71_RS04760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCK71_RS04765	COG4969	Belongs to the N-Me-Phe pilin family
GCK71_RS04775	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK71_RS04780	COG3725	Membrane protein required for beta-lactamase induction
GCK71_RS04785	COG1113	amino acid transport
GCK71_RS04795	COG2186	Transcriptional regulator
GCK71_RS04800	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GCK71_RS04805	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK71_RS04810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK71_RS04820	COG1049	propionate catabolic process, 2-methylcitrate cycle
GCK71_RS04830	COG0697	spore germination
GCK71_RS04850	COG2132	Multicopper oxidase
GCK71_RS04855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GCK71_RS04860	COG0288	reversible hydration of carbon dioxide
GCK71_RS04865	COG1131	(ABC) transporter
GCK71_RS04870	COG0842	Transport permease protein
GCK71_RS04895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GCK71_RS04900	COG0617	tRNA 3'-terminal CCA addition
GCK71_RS04905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCK71_RS04925	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GCK71_RS04930	COG1643	Atp-dependent helicase
GCK71_RS04935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCK71_RS04940	COG1120	ATPase activity
GCK71_RS04945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK71_RS04950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK71_RS04970	COG2860	membrane
GCK71_RS04990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK71_RS04995	COG3850	Histidine kinase
GCK71_RS04995	COG3437	response regulator, receiver
GCK71_RS04995	COG4999	Histidine kinase
GCK71_RS04995	COG2205	protein histidine kinase activity
GCK71_RS05005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCK71_RS05010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK71_RS05015	COG3956	TIGRFAM MazG family protein
GCK71_RS05035	COG0602	queuosine metabolic process
GCK71_RS05040	COG0720	synthase
GCK71_RS05095	COG0529	Catalyzes the synthesis of activated sulfate
GCK71_RS05135	COG4942	peptidase
GCK71_RS05135	COG1388	LysM domain
GCK71_RS05140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCK71_RS05150	COG0698	ribose 5-phosphate isomerase
GCK71_RS05155	COG1063	alcohol dehydrogenase
GCK71_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS05165	COG2376	Dihydroxyacetone kinase
GCK71_RS05180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GCK71_RS05200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK71_RS05205	COG1858	cytochrome C peroxidase
GCK71_RS05215	COG4771	TonB-dependent receptor
GCK71_RS05225	COG0024	Methionine aminopeptidase
GCK71_RS05235	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK71_RS05235	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK71_RS05240	COG1070	Carbohydrate kinase
GCK71_RS05245	COG3623	hexulose-6-phosphate isomerase
GCK71_RS05250	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS05255	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS05260	COG1129	ABC transporter
GCK71_RS05275	COG1349	DNA-binding transcription factor activity
GCK71_RS05280	COG0235	Class ii aldolase
GCK71_RS05285	COG0243	molybdopterin cofactor binding
GCK71_RS05290	COG0437	4 iron, 4 sulfur cluster binding
GCK71_RS05295	COG3302	dmso reductase anchor subunit
GCK71_RS05300	COG3381	protein complex oligomerization
GCK71_RS05305	COG3038	cytochrome b561
GCK71_RS05310	COG3783	Cytochrome b(562)
GCK71_RS05320	COG1879	ABC-type sugar transport system periplasmic component
GCK71_RS05330	COG1129	ABC transporter
GCK71_RS05335	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS05340	COG3959	Transketolase, thiamine diphosphate binding domain
GCK71_RS05345	COG3958	Transketolase
GCK71_RS05350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK71_RS05395	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GCK71_RS05430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK71_RS05435	COG1238	metal cluster binding
GCK71_RS05440	COG2918	glutathione biosynthetic process
GCK71_RS05455	COG4536	flavin adenine dinucleotide binding
GCK71_RS05460	COG4137	Cytochrome C assembly protein
GCK71_RS05465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GCK71_RS05495	COG3137	Salt-induced outer membrane protein
GCK71_RS05505	COG3279	Response regulator of the LytR AlgR family
GCK71_RS05510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK71_RS05515	COG0287	Prephenate dehydrogenase
GCK71_RS05515	COG1605	Chorismate mutase
GCK71_RS05545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCK71_RS05550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK71_RS05560	COG0564	pseudouridine synthase activity
GCK71_RS05570	COG0542	response to heat
GCK71_RS05610	COG5544	Lipoprotein
GCK71_RS05615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK71_RS05620	COG0045	succinate-CoA ligase (ADP-forming) activity
GCK71_RS05620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK71_RS05620	COG1042	CoA-binding domain protein
GCK71_RS05625	COG3148	PFAM DTW domain containing protein
GCK71_RS05630	COG3118	belongs to the thioredoxin family
GCK71_RS05635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK71_RS05640	COG2814	Major facilitator Superfamily
GCK71_RS05645	COG1566	PFAM secretion protein HlyD family protein
GCK71_RS05650	COG1846	Transcriptional regulator
GCK71_RS05660	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GCK71_RS05665	COG2814	Major facilitator Superfamily
GCK71_RS05705	COG0765	amino acid transport
GCK71_RS05715	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK71_RS05740	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
GCK71_RS05750	COG1960	acyl-CoA dehydrogenase activity
GCK71_RS05760	COG0121	glutamine amidotransferase
GCK71_RS05765	COG3034	peptidoglycan biosynthetic process
GCK71_RS05780	COG1805	sodium ion transport
GCK71_RS05785	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK71_RS05805	COG1477	protein flavinylation
GCK71_RS05825	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK71_RS05830	COG0583	DNA-binding transcription factor activity
GCK71_RS05890	COG2226	methyltransferase
GCK71_RS05930	COG1940	carbohydrate kinase activity
GCK71_RS05935	COG0419	ATPase involved in DNA repair
GCK71_RS05940	COG0420	3'-5' exonuclease activity
GCK71_RS05945	COG0745	RESPONSE REGULATOR receiver
GCK71_RS05950	COG5002	protein histidine kinase activity
GCK71_RS05975	COG0366	Alpha amylase catalytic
GCK71_RS06000	COG0450	alkyl hydroperoxide reductase
GCK71_RS06020	COG1862	Preprotein translocase
GCK71_RS06025	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK71_RS06030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK71_RS06060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK71_RS06060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK71_RS06075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GCK71_RS06080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCK71_RS06095	COG0142	geranyltranstransferase activity
GCK71_RS06110	COG0693	protein deglycase activity
GCK71_RS06115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCK71_RS06130	COG2814	Major facilitator Superfamily
GCK71_RS06140	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCK71_RS06145	COG1845	cytochrome c oxidase, subunit III
GCK71_RS06150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCK71_RS06155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCK71_RS06165	COG2223	nitrite transmembrane transporter activity
GCK71_RS06170	COG3056	Lipoprotein
GCK71_RS06175	COG0271	Belongs to the BolA IbaG family
GCK71_RS06200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GCK71_RS06205	COG0776	regulation of translation
GCK71_RS06210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK71_RS06215	COG1555	photosystem II stabilization
GCK71_RS06220	COG0824	Thioesterase
GCK71_RS06230	COG4533	DNA binding
GCK71_RS06245	COG1522	sequence-specific DNA binding
GCK71_RS06250	COG1132	(ABC) transporter
GCK71_RS06255	COG1132	(ABC) transporter
GCK71_RS06260	COG0347	Belongs to the P(II) protein family
GCK71_RS06265	COG0004	ammonium transporteR
GCK71_RS06270	COG1946	Acyl-CoA thioesterase
GCK71_RS06275	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GCK71_RS06280	COG3695	enzyme binding
GCK71_RS06305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK71_RS06315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK71_RS06320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK71_RS06325	COG1309	transcriptional regulator
GCK71_RS06330	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GCK71_RS06335	COG3264	Mechanosensitive ion channel
GCK71_RS06335	COG1196	nuclear chromosome segregation
GCK71_RS06350	COG2832	Protein of unknown function (DUF454)
GCK71_RS06360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GCK71_RS06390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK71_RS06390	COG0543	2 iron, 2 sulfur cluster binding
GCK71_RS06415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK71_RS06460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK71_RS06480	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK71_RS06485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK71_RS06490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK71_RS06490	COG4651	solute:proton antiporter activity
GCK71_RS06495	COG2223	nitrite transmembrane transporter activity
GCK71_RS06510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCK71_RS06515	COG3735	TraB family
GCK71_RS06520	COG2217	Heavy metal translocating P-type atpase
GCK71_RS06525	COG0789	Transcriptional regulator
GCK71_RS06530	COG1585	Membrane protein implicated in regulation of membrane protease activity
GCK71_RS06535	COG0330	HflC and HflK could
GCK71_RS06540	COG3118	belongs to the thioredoxin family
GCK71_RS06545	COG0300	oxidoreductase activity
GCK71_RS06550	COG2755	lipolytic protein G-D-S-L family
GCK71_RS06555	COG4181	ATPase activity
GCK71_RS06560	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GCK71_RS06565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GCK71_RS06570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GCK71_RS06585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK71_RS06600	COG2501	S4 domain
GCK71_RS06635	COG0582	viral genome integration into host DNA
GCK71_RS06650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GCK71_RS06655	COG4589	Belongs to the CDS family
GCK71_RS06665	COG2267	carboxylic ester hydrolase activity
GCK71_RS06670	COG0671	phosphoesterase, PA-phosphatase related
GCK71_RS06670	COG2453	phosphatase
GCK71_RS06705	COG0667	Aldo Keto reductase
GCK71_RS06710	COG0656	L-ascorbic acid biosynthetic process
GCK71_RS06720	COG1472	Belongs to the glycosyl hydrolase 3 family
GCK71_RS06735	COG3328	transposase activity
GCK71_RS06790	COG3423	Transcriptional regulator
GCK71_RS06795	COG4953	penicillin-binding protein 1C
GCK71_RS06805	COG2373	Large extracellular alpha-helical protein
GCK71_RS06825	COG3962	Belongs to the TPP enzyme family
GCK71_RS06840	COG1129	ABC transporter
GCK71_RS06845	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS06850	COG0673	inositol 2-dehydrogenase activity
GCK71_RS06855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK71_RS06865	COG3718	enzyme involved in inositol metabolism
GCK71_RS06875	COG5265	(ABC) transporter
GCK71_RS06900	COG2197	response regulator
GCK71_RS06905	COG1278	Cold shock
GCK71_RS06915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK71_RS06920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK71_RS06945	COG1686	Belongs to the peptidase S11 family
GCK71_RS06950	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK71_RS06955	COG0772	Belongs to the SEDS family
GCK71_RS06960	COG0768	penicillin binding
GCK71_RS06970	COG0799	negative regulation of ribosome biogenesis
GCK71_RS06980	COG1466	dna polymerase III delta subunit
GCK71_RS06995	COG2888	peptidyl-tyrosine sulfation
GCK71_RS07000	COG1126	abc transporter atp-binding protein
GCK71_RS07005	COG0765	amino acid transport
GCK71_RS07010	COG0765	amino acid transport
GCK71_RS07020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GCK71_RS07025	COG4535	Mg2 and Co2 transporter CorC
GCK71_RS07035	COG1702	phosphate starvation-inducible protein PhoH
GCK71_RS07040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GCK71_RS07045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK71_RS07085	COG0367	asparagine synthase
GCK71_RS07090	COG0647	UMP catabolic process
GCK71_RS07095	COG1940	carbohydrate kinase activity
GCK71_RS07095	COG1846	Transcriptional regulator
GCK71_RS07100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GCK71_RS07110	COG2190	(PTS) system
GCK71_RS07110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK71_RS07110	COG1263	PTS System
GCK71_RS07140	COG0735	belongs to the Fur family
GCK71_RS07160	COG0596	Alpha beta hydrolase
GCK71_RS07170	COG0582	viral genome integration into host DNA
GCK71_RS07200	COG2113	Glycine betaine
GCK71_RS07205	COG4176	ABC-type proline glycine betaine transport system permease component
GCK71_RS07210	COG4175	Glycine betaine
GCK71_RS07215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCK71_RS07255	COG1278	Cold shock
GCK71_RS07265	COG0747	negative chemotaxis
GCK71_RS07275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK71_RS07280	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GCK71_RS07285	COG1124	(ABC) transporter
GCK71_RS07290	COG0831	urea catabolic process
GCK71_RS07315	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GCK71_RS07325	COG4413	Urea transporter
GCK71_RS07330	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK71_RS07340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK71_RS07350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK71_RS07360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK71_RS07365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK71_RS07370	COG1447	Phosphotransferase system cellobiose-specific component IIA
GCK71_RS07375	COG2169	Transcriptional regulator
GCK71_RS07375	COG1917	Cupin 2, conserved barrel domain protein
GCK71_RS07395	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GCK71_RS07400	COG0033	Phosphoglucomutase
GCK71_RS07415	COG0745	RESPONSE REGULATOR receiver
GCK71_RS07420	COG2205	protein histidine kinase activity
GCK71_RS07460	COG3272	Protein of unknown function (DUF1722)
GCK71_RS07470	COG5212	phosphodiesterase
GCK71_RS07475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GCK71_RS07485	COG1984	allophanate hydrolase subunit 2
GCK71_RS07535	COG0513	Belongs to the DEAD box helicase family
GCK71_RS07545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GCK71_RS07560	COG3026	antisigma factor binding
GCK71_RS07565	COG3086	response to oxidative stress
GCK71_RS07600	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GCK71_RS07615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK71_RS07620	COG1737	Transcriptional regulator
GCK71_RS07630	COG0560	Phosphoserine phosphatase
GCK71_RS07680	COG2205	protein histidine kinase activity
GCK71_RS07685	COG3170	Tfp pilus assembly protein FimV
GCK71_RS07690	COG2204	response regulator
GCK71_RS07695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK71_RS07695	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GCK71_RS07700	COG0347	Belongs to the P(II) protein family
GCK71_RS07710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK71_RS07710	COG1017	nitric oxide dioxygenase activity
GCK71_RS07730	COG2814	Major facilitator Superfamily
GCK71_RS07735	COG3711	transcriptional antiterminator
GCK71_RS07740	COG3683	transport system, periplasmic component
GCK71_RS07745	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK71_RS07770	COG1104	cysteine desulfurase activity
GCK71_RS07775	COG0822	iron-sulfur transferase activity
GCK71_RS07795	COG0443	Heat shock 70 kDa protein
GCK71_RS07800	COG0633	Ferredoxin
GCK71_RS07805	COG2975	iron-sulfur cluster assembly
GCK71_RS07830	COG3468	outer membrane autotransporter barrel domain protein
GCK71_RS07835	COG3468	outer membrane autotransporter barrel domain protein
GCK71_RS07880	COG2976	Protein conserved in bacteria
GCK71_RS07885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK71_RS07900	COG1645	bacterial-type flagellum-dependent swarming motility
GCK71_RS07915	COG0516	GMP reductase activity
GCK71_RS07915	COG0517	IMP dehydrogenase activity
GCK71_RS07970	COG3328	transposase activity
GCK71_RS07995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK71_RS08005	COG1686	Belongs to the peptidase S11 family
GCK71_RS08010	COG0277	FAD linked oxidase domain protein
GCK71_RS08030	COG2261	transglycosylase associated protein
GCK71_RS08040	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GCK71_RS08055	COG4807	Protein conserved in bacteria
GCK71_RS08075	COG1122	ATPase activity
GCK71_RS08095	COG2897	thiosulfate sulfurtransferase activity
GCK71_RS08100	COG1732	Glycine betaine
GCK71_RS08105	COG1732	Glycine betaine
GCK71_RS08110	COG1174	glycine betaine transport
GCK71_RS08115	COG1125	glycine betaine transport
GCK71_RS08120	COG1174	glycine betaine transport
GCK71_RS08125	COG0531	amino acid
GCK71_RS08130	COG1982	Orn Lys Arg decarboxylase major
GCK71_RS08140	COG0697	spore germination
GCK71_RS08170	COG0814	amino acid
GCK71_RS08185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK71_RS08210	COG2205	protein histidine kinase activity
GCK71_RS08210	COG0784	Response regulator, receiver
GCK71_RS08220	COG2198	Histidine kinase
GCK71_RS08220	COG0642	Histidine kinase
GCK71_RS08225	COG2198	Histidine kinase
GCK71_RS08225	COG0642	Histidine kinase
GCK71_RS08230	COG2223	nitrite transmembrane transporter activity
GCK71_RS08260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCK71_RS08305	COG3395	kinase activity
GCK71_RS08310	COG0235	Class ii aldolase
GCK71_RS08315	COG1349	DNA-binding transcription factor activity
GCK71_RS08320	COG3622	Belongs to the hyi family
GCK71_RS08340	COG4386	tail sheath protein
GCK71_RS08380	COG3299	homolog of phage Mu protein gp47
GCK71_RS08400	COG1737	Transcriptional regulator
GCK71_RS08405	COG2723	6-phospho-beta-galactosidase activity
GCK71_RS08420	COG3157	Type VI secretion system effector, Hcp
GCK71_RS08440	COG3083	sulfuric ester hydrolase activity
GCK71_RS08445	COG3082	Protein of unknown function (DUF1414)
GCK71_RS08470	COG1061	Type III restriction enzyme res subunit
GCK71_RS08475	COG1187	pseudouridine synthase activity
GCK71_RS08480	COG2814	Major facilitator Superfamily
GCK71_RS08490	COG4172	Belongs to the ABC transporter superfamily
GCK71_RS08495	COG4239	(ABC) transporter, permease
GCK71_RS08500	COG4174	ABC transporter (Permease)
GCK71_RS08505	COG4166	transmembrane transport
GCK71_RS08510	COG2200	EAL domain
GCK71_RS08515	COG0791	NLP P60 protein
GCK71_RS08520	COG0671	phosphoesterase, PA-phosphatase related
GCK71_RS08525	COG0523	cobalamin synthesis protein
GCK71_RS08535	COG2186	Transcriptional regulator
GCK71_RS08540	COG0246	Mannitol dehydrogenase
GCK71_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS08600	COG1129	ABC transporter
GCK71_RS08610	COG0494	nUDIX hydrolase
GCK71_RS08620	COG1105	Belongs to the carbohydrate kinase PfkB family
GCK71_RS08625	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GCK71_RS08625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK71_RS08625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK71_RS08630	COG3710	Transcriptional regulator
GCK71_RS08645	COG3121	Chaperone
GCK71_RS08650	COG3188	usher protein
GCK71_RS08660	COG2855	membrane
GCK71_RS08665	COG0583	DNA-binding transcription factor activity
GCK71_RS08670	COG0833	amino acid
GCK71_RS08680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK71_RS08690	COG4771	TonB-dependent receptor
GCK71_RS08700	COG0625	glutathione transferase activity
GCK71_RS08725	COG2011	ABC-type metal ion transport system permease component
GCK71_RS08730	COG1686	Belongs to the peptidase S11 family
GCK71_RS08735	COG0814	amino acid
GCK71_RS08740	COG1349	DNA-binding transcription factor activity
GCK71_RS08750	COG0671	phosphoesterase, PA-phosphatase related
GCK71_RS08785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCK71_RS08790	COG3842	ATPase activity
GCK71_RS08795	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK71_RS08800	COG1177	transmembrane transport
GCK71_RS08815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK71_RS08840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK71_RS08845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK71_RS08850	COG1120	ATPase activity
GCK71_RS08870	COG4160	amino acid transport
GCK71_RS08875	COG4215	(ABC) transporter
GCK71_RS08880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK71_RS08885	COG1126	abc transporter atp-binding protein
GCK71_RS08890	COG1605	Chorismate mutase
GCK71_RS08900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK71_RS08905	COG0702	epimerase
GCK71_RS08910	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GCK71_RS08920	COG0028	Belongs to the TPP enzyme family
GCK71_RS08925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK71_RS08935	COG2431	L-lysine efflux transmembrane transporter activity
GCK71_RS08940	COG3593	DNA synthesis involved in DNA repair
GCK71_RS08945	COG2990	Protein conserved in bacteria
GCK71_RS08950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK71_RS08960	COG1278	Cold shock
GCK71_RS08975	COG0542	response to heat
GCK71_RS08990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GCK71_RS09000	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCK71_RS09010	COG0492	ferredoxin-NADP+ reductase activity
GCK71_RS09020	COG1674	ftsk spoiiie
GCK71_RS09020	COG3107	peptidoglycan biosynthetic process
GCK71_RS09030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GCK71_RS09060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCK71_RS09070	COG1882	Formate acetyltransferase
GCK71_RS09075	COG2116	formate transmembrane transporter activity
GCK71_RS09080	COG1944	ATP diphosphatase activity
GCK71_RS09085	COG0252	asparaginase activity
GCK71_RS09090	COG5295	Hep Hag repeat protein
GCK71_RS09090	COG5295	Hep Hag repeat protein
GCK71_RS09115	COG0539	negative regulation of cytoplasmic translation
GCK71_RS09130	COG2333	competence protein COMEC
GCK71_RS09130	COG0658	competence protein
GCK71_RS09145	COG5383	Protein conserved in bacteria
GCK71_RS09155	COG1278	Cold shock
GCK71_RS09175	COG3173	Aminoglycoside phosphotransferase
GCK71_RS09190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCK71_RS09215	COG2989	Protein conserved in bacteria
GCK71_RS09220	COG3108	Peptidase M15
GCK71_RS09225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK71_RS09235	COG1448	Aminotransferase
GCK71_RS09255	COG0308	aminopeptidase N
GCK71_RS09270	COG3217	Mosc domain protein beta barrel domain protein
GCK71_RS09270	COG0633	Ferredoxin
GCK71_RS09280	COG0488	(ABC) transporter
GCK71_RS09285	COG2995	paraquat-inducible protein a
GCK71_RS09290	COG3008	intermembrane lipid transfer
GCK71_RS09290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK71_RS09295	COG3009	Protein conserved in bacteria
GCK71_RS09305	COG3130	regulation of translation
GCK71_RS09345	COG1067	ATP-dependent peptidase activity
GCK71_RS09370	COG3070	regulator of competence-specific genes
GCK71_RS09375	COG1289	transmembrane transporter activity
GCK71_RS09380	COG3304	Inner membrane component domain
GCK71_RS09385	COG0210	DNA helicase
GCK71_RS09400	COG1832	CoA-binding protein
GCK71_RS09420	COG2920	part of a sulfur-relay system
GCK71_RS09445	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS09455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCK71_RS09460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK71_RS09465	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS09470	COG3425	synthase
GCK71_RS09480	COG1024	Enoyl-CoA hydratase
GCK71_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS09495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCK71_RS09500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCK71_RS09630	COG0488	(ABC) transporter
GCK71_RS09640	COG3328	transposase activity
GCK71_RS09650	COG0303	'Molybdopterin
GCK71_RS09660	COG1136	(ABC) transporter
GCK71_RS09690	COG0583	DNA-binding transcription factor activity
GCK71_RS09695	COG0477	Major facilitator Superfamily
GCK71_RS09705	COG2311	Membrane
GCK71_RS09720	COG4211	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS09725	COG2949	membrane
GCK71_RS09740	COG1346	cytolysis
GCK71_RS09750	COG2814	Major facilitator Superfamily
GCK71_RS09780	COG0489	protein tyrosine kinase activity
GCK71_RS09795	COG2982	Protein involved in outer membrane biogenesis
GCK71_RS09800	COG1253	flavin adenine dinucleotide binding
GCK71_RS09805	COG4114	ferric iron reductase
GCK71_RS09810	COG0076	glutamate decarboxylase activity
GCK71_RS09815	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GCK71_RS09830	COG1120	ATPase activity
GCK71_RS09835	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK71_RS09840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK71_RS09845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK71_RS09860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK71_RS09865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK71_RS09875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GCK71_RS09875	COG0140	phosphoribosyl-ATP diphosphatase activity
GCK71_RS09895	COG0131	Imidazoleglycerol-phosphate dehydratase
GCK71_RS09895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK71_RS09905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GCK71_RS09920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK71_RS09925	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS09930	COG1129	ABC transporter
GCK71_RS09935	COG1129	ABC transporter
GCK71_RS09940	COG0371	Dehydrogenase
GCK71_RS09960	COG0531	amino acid
GCK71_RS09970	COG2925	Exonuclease
GCK71_RS09985	COG3328	transposase activity
GCK71_RS09990	COG1470	cell adhesion involved in biofilm formation
GCK71_RS09990	COG1388	LysM domain
GCK71_RS09995	COG2271	Major facilitator Superfamily
GCK71_RS10000	COG3011	Protein conserved in bacteria
GCK71_RS10005	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS10015	COG4948	Mandelate Racemase Muconate Lactonizing
GCK71_RS10035	COG0534	Mate efflux family protein
GCK71_RS10055	COG3122	Protein conserved in bacteria
GCK71_RS10080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCK71_RS10100	COG2223	nitrite transmembrane transporter activity
GCK71_RS10105	COG3328	transposase activity
GCK71_RS10160	COG1132	(ABC) transporter
GCK71_RS10175	COG2207	Transcriptional regulator
GCK71_RS10215	COG1113	amino acid transport
GCK71_RS10240	COG1496	oxidoreductase activity
GCK71_RS10245	COG2226	methyltransferase
GCK71_RS10275	COG3716	PTS system mannose fructose sorbose family IID component
GCK71_RS10280	COG3715	PTS system
GCK71_RS10285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK71_RS10285	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK71_RS10290	COG1253	flavin adenine dinucleotide binding
GCK71_RS10300	COG1846	Transcriptional regulator
GCK71_RS10315	COG1012	belongs to the aldehyde dehydrogenase family
GCK71_RS10320	COG3384	dioxygenase
GCK71_RS10330	COG3971	2-oxopent-4-enoate hydratase activity
GCK71_RS10345	COG2368	4-hydroxyphenylacetate
GCK71_RS10350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCK71_RS10355	COG1760	l-serine dehydratase
GCK71_RS10380	COG0513	Belongs to the DEAD box helicase family
GCK71_RS10385	COG3141	response to X-ray
GCK71_RS10400	COG1770	oligopeptidase
GCK71_RS10415	COG1528	Iron-storage protein
GCK71_RS10420	COG2372	response to copper ion
GCK71_RS10450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK71_RS10455	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK71_RS10480	COG3418	PFAM FlgN family protein
GCK71_RS10485	COG2747	anti-sigma28 factor FlgM
GCK71_RS10495	COG1815	bacterial-type flagellum-dependent cell motility
GCK71_RS10500	COG1558	bacterial-type flagellum-dependent cell motility
GCK71_RS10540	COG1256	bacterial-type flagellum assembly
GCK71_RS10550	COG2390	Transcriptional regulator
GCK71_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS10555	COG3347	Dehydrogenase
GCK71_RS10560	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS10570	COG1129	ABC transporter
GCK71_RS10575	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS10580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK71_RS10600	COG1987	bacterial-type flagellum assembly
GCK71_RS10625	COG1580	Controls the rotational direction of flagella during chemotaxis
GCK71_RS10640	COG1157	protein secretion by the type III secretion system
GCK71_RS10660	COG1677	Flagellar hook-basal body complex protein FliE
GCK71_RS10680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GCK71_RS10685	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GCK71_RS10690	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GCK71_RS10725	COG1191	sigma factor activity
GCK71_RS10740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK71_RS10745	COG0765	amino acid transport
GCK71_RS10750	COG1126	abc transporter atp-binding protein
GCK71_RS10765	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK71_RS10765	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK71_RS10765	COG0506	proline dehydrogenase activity
GCK71_RS10780	COG0672	)-iron permease
GCK71_RS10785	COG2822	iron ion transport
GCK71_RS10805	COG1113	amino acid transport
GCK71_RS10830	COG3136	membrane protein required for alginate biosynthesis
GCK71_RS10840	COG2197	response regulator
GCK71_RS10985	COG2188	Transcriptional regulator
GCK71_RS10995	COG0673	inositol 2-dehydrogenase activity
GCK71_RS11005	COG1175	transmembrane transport
GCK71_RS11010	COG0395	ABC-type sugar transport system, permease component
GCK71_RS11015	COG3842	ATPase activity
GCK71_RS11090	COG4771	TonB-dependent receptor
GCK71_RS11095	COG1021	2,3-dihydroxybenzoate-AMP ligase
GCK71_RS11115	COG2226	methyltransferase
GCK71_RS11115	COG3433	isochorismatase activity
GCK71_RS11115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK71_RS11130	COG1132	(ABC) transporter
GCK71_RS11135	COG2814	Major facilitator Superfamily
GCK71_RS11140	COG1169	isochorismate synthase
GCK71_RS11145	COG0582	viral genome integration into host DNA
GCK71_RS11155	COG3121	Chaperone
GCK71_RS11165	COG3188	usher protein
GCK71_RS11180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK71_RS11180	COG2205	protein histidine kinase activity
GCK71_RS11190	COG0427	acetyl-CoA hydrolase
GCK71_RS11195	COG2030	dehydratase
GCK71_RS11220	COG2814	Major facilitator Superfamily
GCK71_RS11235	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK71_RS11240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCK71_RS11250	COG1349	DNA-binding transcription factor activity
GCK71_RS11260	COG2066	Belongs to the glutaminase family
GCK71_RS11270	COG0672	)-iron permease
GCK71_RS11285	COG1136	(ABC) transporter
GCK71_RS11285	COG0577	efflux transmembrane transporter activity
GCK71_RS11295	COG1136	(ABC) transporter
GCK71_RS11295	COG0577	efflux transmembrane transporter activity
GCK71_RS11315	COG0006	proline dipeptidase activity
GCK71_RS11320	COG0457	Tetratricopeptide repeat
GCK71_RS11325	COG1649	PFAM Uncharacterised BCR, COG1649
GCK71_RS11325	COG0726	polysaccharide deacetylase
GCK71_RS11330	COG1215	transferase activity, transferring glycosyl groups
GCK71_RS11335	COG3658	cytochrome
GCK71_RS11350	COG1702	phosphate starvation-inducible protein PhoH
GCK71_RS11355	COG0387	Pfam Sodium calcium exchanger
GCK71_RS11360	COG3850	Histidine kinase
GCK71_RS11370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GCK71_RS11435	COG0402	S-adenosylhomocysteine deaminase activity
GCK71_RS11455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK71_RS11500	COG3328	transposase activity
GCK71_RS11525	COG0500	methyltransferase
GCK71_RS11565	COG5002	protein histidine kinase activity
GCK71_RS11620	COG0012	GTP binding
GCK71_RS11635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GCK71_RS11660	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK71_RS11680	COG0659	secondary active sulfate transmembrane transporter activity
GCK71_RS11705	COG3833	ABC-type maltose transport systems, permease component
GCK71_RS11710	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK71_RS11730	COG0584	glycerophosphoryl diester phosphodiesterase
GCK71_RS11735	COG1940	carbohydrate kinase activity
GCK71_RS11750	COG3381	protein complex oligomerization
GCK71_RS11765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK71_RS11775	COG0728	peptidoglycan biosynthetic process
GCK71_RS11795	COG3102	Protein conserved in bacteria
GCK71_RS11815	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GCK71_RS11820	COG1801	Protein of unknown function DUF72
GCK71_RS11830	COG0494	nUDIX hydrolase
GCK71_RS11860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK71_RS11870	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GCK71_RS11875	COG0739	heme binding
GCK71_RS11880	COG1560	Kdo2-lipid A biosynthetic process
GCK71_RS11890	COG0469	pyruvate kinase activity
GCK71_RS11895	COG1737	Transcriptional regulator
GCK71_RS11900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCK71_RS11910	COG0800	Aldolase
GCK71_RS11925	COG0251	oxidation-reduction process
GCK71_RS11930	COG1199	ATP-dependent helicase activity
GCK71_RS11940	COG3065	identical protein binding
GCK71_RS11950	COG0318	PFAM AMP-dependent synthetase and ligase
GCK71_RS11955	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GCK71_RS11960	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GCK71_RS11965	COG2894	cell division
GCK71_RS11980	COG2951	lytic endotransglycosylase activity
GCK71_RS11985	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCK71_RS11995	COG0582	viral genome integration into host DNA
GCK71_RS12090	COG3328	transposase activity
GCK71_RS12255	COG3328	transposase activity
GCK71_RS12265	COG1104	cysteine desulfurase activity
GCK71_RS12300	COG2719	SpoVR family
GCK71_RS12310	COG2814	Major facilitator Superfamily
GCK71_RS12320	COG0583	DNA-binding transcription factor activity
GCK71_RS12335	COG2766	serine protein kinase
GCK71_RS12345	COG3713	MltA-interacting MipA family protein
GCK71_RS12365	COG3139	Protein of unknown function (DUF1315)
GCK71_RS12370	COG1335	isochorismatase
GCK71_RS12375	COG0252	asparaginase activity
GCK71_RS12380	COG0616	signal peptide processing
GCK71_RS12385	COG0778	Nitroreductase
GCK71_RS12390	COG0709	Synthesizes selenophosphate from selenide and ATP
GCK71_RS12395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCK71_RS12405	COG0494	nUDIX hydrolase
GCK71_RS12425	COG0494	nUDIX hydrolase
GCK71_RS12430	COG0708	Exodeoxyribonuclease III
GCK71_RS12435	COG0583	DNA-binding transcription factor activity
GCK71_RS12455	COG3328	transposase activity
GCK71_RS12460	COG0788	formyltetrahydrofolate deformylase activity
GCK71_RS12470	COG0745	RESPONSE REGULATOR receiver
GCK71_RS12505	COG1012	belongs to the aldehyde dehydrogenase family
GCK71_RS12505	COG1454	alcohol dehydrogenase
GCK71_RS12515	COG2095	MarC family integral membrane protein
GCK71_RS12525	COG0601	transmembrane transport
GCK71_RS12530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK71_RS12535	COG0444	Belongs to the ABC transporter superfamily
GCK71_RS12540	COG4608	Belongs to the ABC transporter superfamily
GCK71_RS12580	COG2350	Protein conserved in bacteria
GCK71_RS12585	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GCK71_RS12590	COG3328	transposase activity
GCK71_RS12630	COG3047	cAMP biosynthetic process
GCK71_RS12650	COG0134	indole-3-glycerol-phosphate synthase activity
GCK71_RS12650	COG0135	phosphoribosylanthranilate isomerase activity
GCK71_RS12660	COG0512	Glutamine amidotransferase of anthranilate synthase
GCK71_RS12685	COG0009	L-threonylcarbamoyladenylate synthase
GCK71_RS12690	COG1187	pseudouridine synthase activity
GCK71_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS12705	COG0616	signal peptide processing
GCK71_RS12725	COG0583	DNA-binding transcription factor activity
GCK71_RS12735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GCK71_RS12745	COG0671	phosphoesterase, PA-phosphatase related
GCK71_RS12750	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GCK71_RS12755	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GCK71_RS12770	COG0023	Translation Initiation Factor
GCK71_RS12790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCK71_RS12795	COG2879	small protein
GCK71_RS12800	COG1966	Carbon starvation protein
GCK71_RS12810	COG2271	Major facilitator Superfamily
GCK71_RS12815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK71_RS12820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GCK71_RS12830	COG4659	FMN binding
GCK71_RS12835	COG4658	electron transport chain
GCK71_RS12840	COG2207	Transcriptional regulator
GCK71_RS12840	COG3708	Transcriptional regulator
GCK71_RS12875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK71_RS12880	COG2274	protein secretion by the type I secretion system
GCK71_RS12895	COG1879	ABC-type sugar transport system periplasmic component
GCK71_RS12900	COG1129	ABC transporter
GCK71_RS12905	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS12915	COG0673	inositol 2-dehydrogenase activity
GCK71_RS12920	COG0385	Bile acid
GCK71_RS12930	COG5339	Protein conserved in bacteria
GCK71_RS12940	COG0114	fumarate hydratase activity
GCK71_RS12950	COG2814	Major facilitator Superfamily
GCK71_RS12955	COG0583	DNA-binding transcription factor activity
GCK71_RS12960	COG1940	carbohydrate kinase activity
GCK71_RS12965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCK71_RS12970	COG0038	chloride channel
GCK71_RS12980	COG1609	Transcriptional regulator
GCK71_RS13000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK71_RS13010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCK71_RS13040	COG0028	Belongs to the TPP enzyme family
GCK71_RS13045	COG0440	acetolactate synthase activity
GCK71_RS13050	COG1011	Hydrolase
GCK71_RS13065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK71_RS13070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCK71_RS13075	COG0589	response to stress
GCK71_RS13080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GCK71_RS13085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GCK71_RS13100	COG0531	amino acid
GCK71_RS13110	COG0745	RESPONSE REGULATOR receiver
GCK71_RS13115	COG2205	protein histidine kinase activity
GCK71_RS13120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GCK71_RS13155	COG3591	Belongs to the peptidase S1B family
GCK71_RS13170	COG1643	Atp-dependent helicase
GCK71_RS13180	COG2390	Transcriptional regulator
GCK71_RS13185	COG0246	Mannitol dehydrogenase
GCK71_RS13190	COG3784	Protein of unknown function (DUF1318)
GCK71_RS13200	COG2911	Protein conserved in bacteria
GCK71_RS13205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK71_RS13210	COG3187	Heat shock protein
GCK71_RS13215	COG3042	response to heat
GCK71_RS13220	COG1285	pathogenesis
GCK71_RS13230	COG0674	pyruvate-flavodoxin oxidoreductase activity
GCK71_RS13230	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GCK71_RS13230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK71_RS13230	COG1013	pyruvate-flavodoxin oxidoreductase activity
GCK71_RS13240	COG0657	acetylesterase activity
GCK71_RS13260	COG4166	transmembrane transport
GCK71_RS13265	COG2866	Carboxypeptidase
GCK71_RS13270	COG4948	Mandelate Racemase Muconate Lactonizing
GCK71_RS13275	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GCK71_RS13290	COG5642	Protein of unknown function (DUF2384)
GCK71_RS13295	COG5654	RES domain protein
GCK71_RS13305	COG3106	COG3106 Predicted ATPase
GCK71_RS13315	COG1983	PspC domain protein
GCK71_RS13325	COG1842	Phage shock protein A
GCK71_RS13330	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GCK71_RS13345	COG4166	transmembrane transport
GCK71_RS13350	COG4168	peptide transport system, permease
GCK71_RS13355	COG4171	peptide transport system, permease
GCK71_RS13365	COG4172	Belongs to the ABC transporter superfamily
GCK71_RS13370	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK71_RS13370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK71_RS13375	COG3104	oligopeptide transport
GCK71_RS13390	COG0625	glutathione transferase activity
GCK71_RS13410	COG3895	Periplasmic Protein
GCK71_RS13420	COG3133	Outer membrane lipoprotein
GCK71_RS13435	COG2194	sulfuric ester hydrolase activity
GCK71_RS13440	COG1309	transcriptional regulator
GCK71_RS13445	COG1902	pentaerythritol trinitrate reductase activity
GCK71_RS13455	COG0346	lactoylglutathione lyase activity
GCK71_RS13460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCK71_RS13470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GCK71_RS13480	COG0791	NLP P60 protein
GCK71_RS13500	COG0583	DNA-binding transcription factor activity
GCK71_RS13505	COG2814	Major facilitator Superfamily
GCK71_RS13510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCK71_RS13515	COG0307	riboflavin synthase, alpha
GCK71_RS13565	COG1376	ErfK ybiS ycfS ynhG family protein
GCK71_RS13565	COG1388	LysM domain
GCK71_RS13580	COG0719	Fe-S assembly protein
GCK71_RS13585	COG0396	ATPase activity
GCK71_RS13590	COG0719	Fe-S assembly protein
GCK71_RS13595	COG0316	Belongs to the HesB IscA family
GCK71_RS13605	COG2050	protein possibly involved in aromatic compounds catabolism
GCK71_RS13610	COG0247	lactate metabolic process
GCK71_RS13610	COG0277	FAD linked oxidase domain protein
GCK71_RS13615	COG0628	permease
GCK71_RS13625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK71_RS13625	COG0574	Belongs to the PEP-utilizing enzyme family
GCK71_RS13650	COG0791	NLP P60 protein
GCK71_RS13700	COG0386	Belongs to the glutathione peroxidase family
GCK71_RS13715	COG0776	regulation of translation
GCK71_RS13720	COG0072	phenylalanine-tRNA ligase activity
GCK71_RS13720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCK71_RS13755	COG4249	Peptidase C14 caspase catalytic subunit p20
GCK71_RS13780	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCK71_RS13785	COG1121	(ABC) transporter
GCK71_RS13790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK71_RS13795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK71_RS13805	COG3001	Fructosamine kinase
GCK71_RS13815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK71_RS13820	COG3328	transposase activity
GCK71_RS13825	COG1917	Cupin 2, conserved barrel domain protein
GCK71_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS13845	COG1175	transmembrane transport
GCK71_RS13850	COG0395	ABC-type sugar transport system, permease component
GCK71_RS13855	COG3842	ATPase activity
GCK71_RS13860	COG1653	transport
GCK71_RS13865	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK71_RS13870	COG1988	membrane-bound metal-dependent
GCK71_RS13875	COG1823	symporter activity
GCK71_RS13880	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK71_RS13890	COG0823	Involved in the tonB-independent uptake of proteins
GCK71_RS13895	COG2814	Major facilitator Superfamily
GCK71_RS13900	COG3121	Chaperone
GCK71_RS13915	COG3121	Chaperone
GCK71_RS13920	COG3539	Fimbrial protein
GCK71_RS13935	COG0793	Belongs to the peptidase S41A family
GCK71_RS13945	COG1956	GAF domain-containing protein
GCK71_RS13950	COG2995	paraquat-inducible protein a
GCK71_RS13955	COG3008	intermembrane lipid transfer
GCK71_RS13975	COG3121	Chaperone
GCK71_RS14030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCK71_RS14040	COG5295	Hep Hag repeat protein
GCK71_RS14050	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK71_RS14060	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GCK71_RS14065	COG0745	RESPONSE REGULATOR receiver
GCK71_RS14075	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCK71_RS14080	COG0840	transmembrane signaling receptor activity
GCK71_RS14085	COG0840	transmembrane signaling receptor activity
GCK71_RS14105	COG2964	Protein conserved in bacteria
GCK71_RS14115	COG0251	oxidation-reduction process
GCK71_RS14120	COG2271	Major facilitator Superfamily
GCK71_RS14125	COG0835	chemotaxis
GCK71_RS14130	COG2198	Histidine kinase
GCK71_RS14130	COG0643	Histidine kinase
GCK71_RS14135	COG1360	Flagellar Motor Protein
GCK71_RS14160	COG1285	pathogenesis
GCK71_RS14185	COG0604	alcohol dehydrogenase
GCK71_RS14185	COG3321	synthase
GCK71_RS14185	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS14195	COG1522	sequence-specific DNA binding
GCK71_RS14215	COG1733	regulation of RNA biosynthetic process
GCK71_RS14220	COG0702	epimerase
GCK71_RS14225	COG0840	transmembrane signaling receptor activity
GCK71_RS14240	COG0538	isocitrate dehydrogenase activity
GCK71_RS14245	COG1187	pseudouridine synthase activity
GCK71_RS14265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GCK71_RS14275	COG0745	RESPONSE REGULATOR receiver
GCK71_RS14285	COG2850	peptidyl-arginine hydroxylation
GCK71_RS14310	COG1940	carbohydrate kinase activity
GCK71_RS14315	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK71_RS14325	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK71_RS14330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GCK71_RS14335	COG3134	Outer membrane lipoprotein
GCK71_RS14345	COG3328	transposase activity
GCK71_RS14365	COG1252	NADH dehydrogenase
GCK71_RS14375	COG1472	Belongs to the glycosyl hydrolase 3 family
GCK71_RS14390	COG5633	Lipoprotein
GCK71_RS14395	COG0537	adenosine 5'-monophosphoramidase activity
GCK71_RS14400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCK71_RS14410	COG1263	PTS System
GCK71_RS14410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK71_RS14415	COG0084	hydrolase, TatD family'
GCK71_RS14420	COG0470	DNA polymerase III
GCK71_RS14430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GCK71_RS14435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK71_RS14445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK71_RS14475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GCK71_RS14480	COG1399	metal-binding, possibly nucleic acid-binding protein
GCK71_RS14485	COG0424	maF-like protein
GCK71_RS14490	COG0564	pseudouridine synthase activity
GCK71_RS14495	COG1530	ribonuclease E activity
GCK71_RS14510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GCK71_RS14535	COG3328	transposase activity
GCK71_RS14555	COG0628	permease
GCK71_RS14575	COG3916	Acyl-homoserine-lactone synthase
GCK71_RS14580	COG2771	luxR family
GCK71_RS14585	COG0583	DNA-binding transcription factor activity
GCK71_RS14595	COG0477	Major facilitator Superfamily
GCK71_RS14605	COG0667	Aldo Keto reductase
GCK71_RS14630	COG1203	CRISPR-associated helicase, Cas3
GCK71_RS14635	COG1518	maintenance of DNA repeat elements
GCK71_RS14640	COG0668	transmembrane transport
GCK71_RS14660	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCK71_RS14665	COG0395	ABC-type sugar transport system, permease component
GCK71_RS14680	COG1609	Transcriptional regulator
GCK71_RS14690	COG3842	ATPase activity
GCK71_RS14700	COG3210	domain, Protein
GCK71_RS14705	COG3210	domain, Protein
GCK71_RS14725	COG3210	domain, Protein
GCK71_RS14745	COG3210	domain, Protein
GCK71_RS14750	COG2831	hemolysin activation secretion protein
GCK71_RS14755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK71_RS14765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK71_RS14775	COG0473	3-isopropylmalate dehydrogenase activity
GCK71_RS14780	COG0583	DNA-binding transcription factor activity
GCK71_RS14785	COG1609	Transcriptional regulator
GCK71_RS14790	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS14795	COG1129	ABC transporter
GCK71_RS14800	COG1879	ABC-type sugar transport system periplasmic component
GCK71_RS14805	COG1063	alcohol dehydrogenase
GCK71_RS14825	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCK71_RS14855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK71_RS14860	COG0765	amino acid transport
GCK71_RS14865	COG1126	abc transporter atp-binding protein
GCK71_RS14910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCK71_RS14925	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GCK71_RS14940	COG1169	isochorismate synthase
GCK71_RS14950	COG4575	ribosome binding
GCK71_RS14965	COG0129	dihydroxy-acid dehydratase activity
GCK71_RS14980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK71_RS14985	COG1609	Transcriptional regulator
GCK71_RS14990	COG1649	PFAM Uncharacterised BCR, COG1649
GCK71_RS14995	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS15000	COG3265	gluconokinase activity
GCK71_RS15005	COG2731	YhcH YjgK YiaL family protein
GCK71_RS15020	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK71_RS15025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GCK71_RS15035	COG0839	Belongs to the complex I subunit 6 family
GCK71_RS15050	COG1034	ATP synthesis coupled electron transport
GCK71_RS15070	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK71_RS15080	COG0583	DNA-binding transcription factor activity
GCK71_RS15085	COG0436	Aminotransferase
GCK71_RS15100	COG0471	metal ion transport
GCK71_RS15100	COG0490	domain, Protein
GCK71_RS15105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK71_RS15125	COG0857	belongs to the CobB CobQ family
GCK71_RS15125	COG0280	phosphate acetyltransferase
GCK71_RS15130	COG1609	Transcriptional regulator
GCK71_RS15150	COG3328	transposase activity
GCK71_RS15155	COG3037	sugar-specific permease SgaT UlaA
GCK71_RS15160	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GCK71_RS15175	COG1090	epimerase
GCK71_RS15180	COG4598	ABC transporter
GCK71_RS15185	COG4160	amino acid transport
GCK71_RS15190	COG4215	(ABC) transporter
GCK71_RS15195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK71_RS15205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GCK71_RS15210	COG1286	toxin biosynthetic process
GCK71_RS15215	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GCK71_RS15220	COG0285	dihydrofolate synthase activity
GCK71_RS15230	COG0586	Pfam SNARE associated Golgi protein
GCK71_RS15240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK71_RS15255	COG0697	spore germination
GCK71_RS15270	COG1794	racemase activity, acting on amino acids and derivatives
GCK71_RS15275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK71_RS15290	COG3101	peptidyl-lysine hydroxylation
GCK71_RS15295	COG0730	response to heat
GCK71_RS15310	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK71_RS15320	COG2062	phosphohistidine phosphatase, SixA
GCK71_RS15335	COG3691	Protein conserved in bacteria
GCK71_RS15350	COG3088	subunit of a heme lyase
GCK71_RS15350	COG4235	cytochrome complex assembly
GCK71_RS15355	COG3088	subunit of a heme lyase
GCK71_RS15355	COG4235	cytochrome complex assembly
GCK71_RS15360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCK71_RS15365	COG1138	Cytochrome C-type biogenesis protein
GCK71_RS15375	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK71_RS15380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK71_RS15385	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK71_RS15405	COG1704	LemA family
GCK71_RS15415	COG2824	Alkylphosphonate utilization operon protein PhnA
GCK71_RS15425	COG3328	transposase activity
GCK71_RS15510	COG3188	usher protein
GCK71_RS15515	COG3328	transposase activity
GCK71_RS15525	COG3188	usher protein
GCK71_RS15530	COG3121	Chaperone
GCK71_RS15590	COG2951	lytic endotransglycosylase activity
GCK71_RS15625	COG0243	molybdopterin cofactor binding
GCK71_RS15630	COG0437	4 iron, 4 sulfur cluster binding
GCK71_RS15635	COG3302	dmso reductase anchor subunit
GCK71_RS15640	COG3381	protein complex oligomerization
GCK71_RS15670	COG3038	cytochrome b561
GCK71_RS15680	COG0436	Aminotransferase
GCK71_RS15705	COG0667	Aldo Keto reductase
GCK71_RS15720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK71_RS15790	COG3530	Putative quorum-sensing-regulated virulence factor
GCK71_RS15805	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GCK71_RS15815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK71_RS15845	COG2205	protein histidine kinase activity
GCK71_RS15850	COG0745	RESPONSE REGULATOR receiver
GCK71_RS15855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK71_RS15870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GCK71_RS15890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GCK71_RS15900	COG3850	Histidine kinase
GCK71_RS15900	COG5002	protein histidine kinase activity
GCK71_RS15905	COG0745	RESPONSE REGULATOR receiver
GCK71_RS15920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GCK71_RS15925	COG4208	sulfate ABC transporter
GCK71_RS15930	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GCK71_RS15935	COG4150	thiosulfate binding
GCK71_RS15945	COG1737	Transcriptional regulator
GCK71_RS15955	COG2731	YhcH YjgK YiaL family protein
GCK71_RS15965	COG4886	Leucine-rich repeat (LRR) protein
GCK71_RS15975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCK71_RS15980	COG2837	iron assimilation
GCK71_RS15990	COG3111	PFAM Bacterial OB fold (BOF) protein
GCK71_RS16035	COG3005	denitrification pathway
GCK71_RS16040	COG3043	anaerobic respiration
GCK71_RS16050	COG3062	negative regulation of establishment of protein localization
GCK71_RS16055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK71_RS16055	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK71_RS16060	COG2197	response regulator
GCK71_RS16070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK71_RS16080	COG1988	membrane-bound metal-dependent
GCK71_RS16085	COG0641	radical SAM
GCK71_RS16090	COG3119	arylsulfatase activity
GCK71_RS16100	COG3842	ATPase activity
GCK71_RS16105	COG1175	transmembrane transport
GCK71_RS16120	COG1393	Belongs to the ArsC family
GCK71_RS16130	COG1876	peptidase activity
GCK71_RS16155	COG2321	neutral zinc metallopeptidase
GCK71_RS16175	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GCK71_RS16185	COG2716	regulation of RNA biosynthetic process
GCK71_RS16190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCK71_RS16205	COG0628	permease
GCK71_RS16210	COG4783	chaperone-mediated protein folding
GCK71_RS16215	COG1393	Belongs to the ArsC family
GCK71_RS16240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GCK71_RS16245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK71_RS16260	COG0581	inorganic phosphate transmembrane transporter activity
GCK71_RS16270	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GCK71_RS16285	COG2239	Acts as a magnesium transporter
GCK71_RS16290	COG0443	Heat shock 70 kDa protein
GCK71_RS16295	COG1177	transmembrane transport
GCK71_RS16300	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK71_RS16310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCK71_RS16320	COG3842	ATPase activity
GCK71_RS16350	COG0745	RESPONSE REGULATOR receiver
GCK71_RS16355	COG3422	double-strand break repair
GCK71_RS16360	COG0826	peptidase U32
GCK71_RS16385	COG0351	phosphomethylpyrimidine kinase
GCK71_RS16400	COG3328	transposase activity
GCK71_RS16435	COG0513	Belongs to the DEAD box helicase family
GCK71_RS16440	COG1309	transcriptional regulator
GCK71_RS16450	COG1131	(ABC) transporter
GCK71_RS16455	COG0842	Transport permease protein
GCK71_RS16460	COG0842	Transport permease protein
GCK71_RS16480	COG1902	pentaerythritol trinitrate reductase activity
GCK71_RS16515	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GCK71_RS16525	COG0583	DNA-binding transcription factor activity
GCK71_RS16530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK71_RS16555	COG0670	Belongs to the BI1 family
GCK71_RS16560	COG0314	molybdopterin synthase activity
GCK71_RS16565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GCK71_RS16575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GCK71_RS16580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GCK71_RS16585	COG4628	conserved protein (DUF2132)
GCK71_RS16595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GCK71_RS16605	COG2226	methyltransferase
GCK71_RS16630	COG0561	phosphatase activity
GCK71_RS16640	COG4149	molybdate abc transporter
GCK71_RS16645	COG0725	ABC transporter, periplasmic molybdate-binding protein
GCK71_RS16655	COG3585	molybdate ion transport
GCK71_RS16655	COG2005	Transcriptional regulator
GCK71_RS16665	COG1119	ATPase activity
GCK71_RS16675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCK71_RS16680	COG1085	galactose-1-phosphate uridylyltransferase
GCK71_RS16695	COG2017	converts alpha-aldose to the beta-anomer
GCK71_RS16710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK71_RS16715	COG1230	cation diffusion facilitator family transporter
GCK71_RS16745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GCK71_RS16750	COG2885	chlorophyll binding
GCK71_RS16760	COG3064	Membrane
GCK71_RS16760	COG3064	Membrane
GCK71_RS16765	COG0848	biopolymer transport protein
GCK71_RS16770	COG0811	peptide transport
GCK71_RS16775	COG0824	Thioesterase
GCK71_RS16780	COG3790	cyd operon protein YbgE
GCK71_RS16785	COG4890	Cyd operon protein YbgT
GCK71_RS16790	COG1294	oxidase, subunit
GCK71_RS16795	COG1271	oxidase subunit
GCK71_RS16800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GCK71_RS16810	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK71_RS16815	COG0567	Dehydrogenase, E1 component
GCK71_RS16825	COG1053	succinate dehydrogenase
GCK71_RS16830	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GCK71_RS16835	COG2009	succinate dehydrogenase
GCK71_RS16850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GCK71_RS16855	COG0497	DNA recombination
GCK71_RS16860	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK71_RS16870	COG2867	negative regulation of translational initiation
GCK71_RS16895	COG0582	viral genome integration into host DNA
GCK71_RS16955	COG3657	addiction module killer protein
GCK71_RS16980	COG1953	Uracil, thiamine, allantoin
GCK71_RS17000	COG2226	methyltransferase
GCK71_RS17005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK71_RS17010	COG0741	lytic transglycosylase activity
GCK71_RS17010	COG1388	LysM domain
GCK71_RS17025	COG0656	L-ascorbic acid biosynthetic process
GCK71_RS17060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK71_RS17070	COG2011	ABC-type metal ion transport system permease component
GCK71_RS17075	COG1464	Belongs to the NlpA lipoprotein family
GCK71_RS17085	COG1720	tRNA m6t6A37 methyltransferase activity
GCK71_RS17095	COG3015	lipoprotein NlpE involved in copper resistance
GCK71_RS17105	COG4681	YaeQ
GCK71_RS17115	COG4568	rho-dependent transcription termination
GCK71_RS17125	COG0037	tRNA processing
GCK71_RS17130	COG0346	lactoylglutathione lyase activity
GCK71_RS17140	COG0587	DNA-directed DNA polymerase activity
GCK71_RS17165	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GCK71_RS17180	COG0750	zinc metalloprotease
GCK71_RS17185	COG0575	Belongs to the CDS family
GCK71_RS17255	COG0564	pseudouridine synthase activity
GCK71_RS17260	COG3098	single-species biofilm formation
GCK71_RS17280	COG1611	Belongs to the LOG family
GCK71_RS17300	COG2363	Small membrane protein
GCK71_RS17305	COG0583	DNA-binding transcription factor activity
GCK71_RS17315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCK71_RS17320	COG2166	iron-sulfur cluster assembly
GCK71_RS17325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GCK71_RS17330	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GCK71_RS17345	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK71_RS17355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GCK71_RS17360	COG1074	ATP-dependent DNA helicase activity
GCK71_RS17370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GCK71_RS17440	COG0667	Aldo Keto reductase
GCK71_RS17470	COG1609	Transcriptional regulator
GCK71_RS17480	COG0583	DNA-binding transcription factor activity
GCK71_RS17485	COG2814	Major facilitator Superfamily
GCK71_RS17490	COG0583	DNA-binding transcription factor activity
GCK71_RS17505	COG0840	transmembrane signaling receptor activity
GCK71_RS17550	COG2165	general secretion pathway protein
GCK71_RS17575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCK71_RS17595	COG0288	reversible hydration of carbon dioxide
GCK71_RS17640	COG3119	arylsulfatase activity
GCK71_RS17645	COG1349	DNA-binding transcription factor activity
GCK71_RS17655	COG2222	sugar isomerase
GCK71_RS17660	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK71_RS17665	COG3715	PTS system
GCK71_RS17670	COG3716	PTS system mannose fructose sorbose family IID component
GCK71_RS17675	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK71_RS17685	COG1028	Short-chain dehydrogenase reductase Sdr
GCK71_RS17695	COG0641	radical SAM
GCK71_RS17700	COG3119	arylsulfatase activity
GCK71_RS17730	COG2271	Major facilitator Superfamily
GCK71_RS17750	COG1263	PTS System
GCK71_RS17750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK71_RS17755	COG1874	Beta-galactosidase
GCK71_RS17760	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GCK71_RS17765	COG3833	ABC-type maltose transport systems, permease component
GCK71_RS17770	COG1175	transmembrane transport
GCK71_RS17775	COG2182	Extracellular solute-binding protein
GCK71_RS17785	COG1129	ABC transporter
GCK71_RS17790	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS17795	COG1879	ABC-type sugar transport system periplasmic component
GCK71_RS17805	COG0791	NLP P60 protein
GCK71_RS17810	COG1695	Transcriptional regulator
GCK71_RS17900	COG2944	sequence-specific DNA binding
GCK71_RS17925	COG0582	viral genome integration into host DNA
GCK71_RS17945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GCK71_RS17950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK71_RS17955	COG4974	Belongs to the 'phage' integrase family
GCK71_RS17960	COG0716	FMN binding
GCK71_RS17965	COG4452	Inner membrane protein CreD
GCK71_RS17970	COG2205	protein histidine kinase activity
GCK71_RS17975	COG0745	RESPONSE REGULATOR receiver
GCK71_RS18000	COG1272	protein, Hemolysin III
GCK71_RS18045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK71_RS18050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK71_RS18055	COG0006	proline dipeptidase activity
GCK71_RS18075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GCK71_RS18080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCK71_RS18115	COG0191	fructose-bisphosphate aldolase activity
GCK71_RS18135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GCK71_RS18140	COG0501	Belongs to the peptidase M48B family
GCK71_RS18155	COG1166	arginine decarboxylase activity
GCK71_RS18170	COG2356	endonuclease I
GCK71_RS18175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GCK71_RS18180	COG0189	ligase activity
GCK71_RS18195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK71_RS18205	COG2805	Type II/IV secretion system protein
GCK71_RS18210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GCK71_RS18215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCK71_RS18225	COG0762	integral membrane protein
GCK71_RS18235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GCK71_RS18240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK71_RS18245	COG3064	Membrane
GCK71_RS18245	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GCK71_RS18245	COG1073	alpha beta
GCK71_RS18265	COG3171	Protein conserved in bacteria
GCK71_RS18275	COG1194	a g-specific adenine glycosylase
GCK71_RS18295	COG4774	siderophore transport
GCK71_RS18300	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS18305	COG1129	ABC transporter
GCK71_RS18310	COG1879	ABC-type sugar transport system periplasmic component
GCK71_RS18315	COG1982	Orn Lys Arg decarboxylase major
GCK71_RS18445	COG3916	Acyl-homoserine-lactone synthase
GCK71_RS18450	COG2771	luxR family
GCK71_RS18500	COG2211	Major facilitator Superfamily
GCK71_RS18520	COG0471	metal ion transport
GCK71_RS18550	COG3501	Rhs element vgr protein
GCK71_RS18565	COG2610	gluconate transmembrane transporter activity
GCK71_RS18580	COG1132	(ABC) transporter
GCK71_RS18585	COG1132	(ABC) transporter
GCK71_RS18585	COG2375	cellular response to nickel ion
GCK71_RS18610	COG3433	isochorismatase activity
GCK71_RS18610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK71_RS18610	COG2226	methyltransferase
GCK71_RS18620	COG3433	isochorismatase activity
GCK71_RS18620	COG2226	methyltransferase
GCK71_RS18620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK71_RS18645	COG3162	membrane
GCK71_RS18655	COG1301	dicarboxylic acid transport
GCK71_RS18765	COG2391	methyltransferase activity
GCK71_RS18770	COG0425	Belongs to the sulfur carrier protein TusA family
GCK71_RS18775	COG0583	DNA-binding transcription factor activity
GCK71_RS18780	COG0814	amino acid
GCK71_RS18785	COG0626	cystathionine gamma-synthase activity
GCK71_RS18795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK71_RS18800	COG4558	Periplasmic binding protein
GCK71_RS18805	COG3720	iron ion transport
GCK71_RS18810	COG4771	TonB-dependent receptor
GCK71_RS18820	COG0702	epimerase
GCK71_RS18825	COG3721	Heme iron utilization protein
GCK71_RS18850	COG1358	cellular component organization or biogenesis
GCK71_RS18910	COG3121	Chaperone
GCK71_RS18965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GCK71_RS18975	COG0735	belongs to the Fur family
GCK71_RS18980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK71_RS19005	COG1448	Aminotransferase
GCK71_RS19010	COG2315	Protein conserved in bacteria
GCK71_RS19015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCK71_RS19020	COG0629	single-stranded DNA binding
GCK71_RS19030	COG1454	alcohol dehydrogenase
GCK71_RS19100	COG1309	transcriptional regulator
GCK71_RS19110	COG0493	'glutamate synthase
GCK71_RS19110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK71_RS19115	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK71_RS19120	COG3383	formate dehydrogenase (NAD+) activity
GCK71_RS19135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GCK71_RS19185	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GCK71_RS19195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCK71_RS19200	COG1053	succinate dehydrogenase
GCK71_RS19215	COG1511	domain protein
GCK71_RS19215	COG3264	Mechanosensitive ion channel
GCK71_RS19235	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GCK71_RS19255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GCK71_RS19260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GCK71_RS19260	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GCK71_RS19265	COG0802	atpase or kinase
GCK71_RS19270	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK71_RS19290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCK71_RS19295	COG0330	HflC and HflK could
GCK71_RS19300	COG0330	HflC and HflK could
GCK71_RS19305	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GCK71_RS19320	COG0557	exoribonuclease II activity
GCK71_RS19325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK71_RS19330	COG1960	acyl-CoA dehydrogenase activity
GCK71_RS19335	COG3650	response to hydrogen peroxide
GCK71_RS19355	COG1073	alpha beta
GCK71_RS19365	COG0360	Binds together with S18 to 16S ribosomal RNA
GCK71_RS19375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GCK71_RS19395	COG3061	Opacity-associated protein A
GCK71_RS19400	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK71_RS19410	COG0737	Belongs to the 5'-nucleotidase family
GCK71_RS19420	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GCK71_RS19430	COG1253	flavin adenine dinucleotide binding
GCK71_RS19440	COG0729	surface antigen
GCK71_RS19445	COG2911	Protein conserved in bacteria
GCK71_RS19450	COG2105	PFAM AIG2 family protein
GCK71_RS19455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GCK71_RS19460	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GCK71_RS19465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCK71_RS19490	COG3423	Transcriptional regulator
GCK71_RS19500	COG0142	geranyltranstransferase activity
GCK71_RS19515	COG0697	spore germination
GCK71_RS19525	COG0642	Histidine kinase
GCK71_RS19530	COG0745	RESPONSE REGULATOR receiver
GCK71_RS19535	COG2027	D-alanyl-D-alanine carboxypeptidase
GCK71_RS19545	COG1534	Rna-binding protein
GCK71_RS19560	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GCK71_RS19570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCK71_RS19590	COG0195	Participates in both transcription termination and antitermination
GCK71_RS19630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK71_RS19685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GCK71_RS19690	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK71_RS19695	COG4771	TonB-dependent receptor
GCK71_RS19720	COG0583	DNA-binding transcription factor activity
GCK71_RS19725	COG1741	Belongs to the pirin family
GCK71_RS19735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GCK71_RS19755	COG2823	Periplasmic or secreted lipoprotein
GCK71_RS19765	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GCK71_RS19775	COG0784	Response regulator, receiver
GCK71_RS19775	COG2198	Histidine kinase
GCK71_RS19775	COG5002	protein histidine kinase activity
GCK71_RS19785	COG1242	4 iron, 4 sulfur cluster binding
GCK71_RS19790	COG0070	glutamate synthase
GCK71_RS19790	COG0067	glutamate synthase
GCK71_RS19790	COG0069	glutamate synthase activity
GCK71_RS19795	COG0493	'glutamate synthase
GCK71_RS19805	COG2969	positive regulation of protein catabolic process
GCK71_RS19810	COG0625	glutathione transferase activity
GCK71_RS19830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GCK71_RS19835	COG3105	Protein conserved in bacteria
GCK71_RS19840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK71_RS19850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK71_RS19860	COG5007	Belongs to the BolA IbaG family
GCK71_RS19865	COG3113	response to antibiotic
GCK71_RS19870	COG2854	intermembrane phospholipid transfer
GCK71_RS19875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK71_RS19880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GCK71_RS19885	COG1127	ABC transporter
GCK71_RS19890	COG0530	calcium, potassium:sodium antiporter activity
GCK71_RS19895	COG0517	IMP dehydrogenase activity
GCK71_RS19895	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GCK71_RS19900	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GCK71_RS19905	COG3117	lipopolysaccharide transmembrane transporter activity
GCK71_RS19910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GCK71_RS19915	COG1137	ATPase activity
GCK71_RS19920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GCK71_RS19945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK71_RS19975	COG1609	Transcriptional regulator
GCK71_RS19980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK71_RS19980	COG1263	PTS System
GCK71_RS19985	COG0366	Alpha amylase catalytic
GCK71_RS19990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK71_RS19995	COG3783	Cytochrome b(562)
GCK71_RS20005	COG0312	modulator of DNA gyrase
GCK71_RS20015	COG2732	(Barnase) inhibitor
GCK71_RS20045	COG0583	DNA-binding transcription factor activity
GCK71_RS20095	COG0312	modulator of DNA gyrase
GCK71_RS20100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK71_RS20105	COG3164	Protein of unknown function
GCK71_RS20110	COG1530	ribonuclease E activity
GCK71_RS20115	COG0424	maF-like protein
GCK71_RS20120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GCK71_RS20125	COG1792	Involved in formation and maintenance of cell shape
GCK71_RS20130	COG1077	Cell shape determining protein MreB Mrl
GCK71_RS20135	COG2199	diguanylate cyclase activity
GCK71_RS20135	COG2200	EAL domain
GCK71_RS20140	COG0604	alcohol dehydrogenase
GCK71_RS20145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GCK71_RS20160	COG0511	ligase activity, forming carbon-carbon bonds
GCK71_RS20165	COG0439	Biotin carboxylase
GCK71_RS20170	COG3924	membrane
GCK71_RS20175	COG4145	pantothenate transmembrane transporter activity
GCK71_RS20185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK71_RS20190	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GCK71_RS20220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK71_RS20230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK71_RS20235	COG3133	Outer membrane lipoprotein
GCK71_RS20245	COG1278	Cold shock
GCK71_RS20250	COG1278	Cold shock
GCK71_RS20270	COG0625	glutathione transferase activity
GCK71_RS20280	COG1069	ribulokinase activity
GCK71_RS20290	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS20295	COG1129	ABC transporter
GCK71_RS20305	COG1560	Kdo2-lipid A biosynthetic process
GCK71_RS20315	COG0025	NhaP-type Na H and K H
GCK71_RS20320	COG2252	PERMEase
GCK71_RS20325	COG3077	Addiction module antitoxin, RelB DinJ family
GCK71_RS20340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK71_RS20350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK71_RS20355	COG0431	NADPH-dependent FMN reductase
GCK71_RS20360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCK71_RS20365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK71_RS20370	COG1869	D-ribose catabolic process
GCK71_RS20375	COG2207	Transcriptional regulator
GCK71_RS20375	COG1917	Cupin 2, conserved barrel domain protein
GCK71_RS20380	COG0673	inositol 2-dehydrogenase activity
GCK71_RS20400	COG3209	COG3209 Rhs family protein
GCK71_RS20415	COG3501	Rhs element vgr protein
GCK71_RS20460	COG3501	Rhs element vgr protein
GCK71_RS20560	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK71_RS20565	COG0058	SHG alpha-glucan phosphorylase activity
GCK71_RS20590	COG3275	phosphorelay sensor kinase activity
GCK71_RS20620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK71_RS20625	COG2095	MarC family integral membrane protein
GCK71_RS20645	COG3265	gluconokinase activity
GCK71_RS20650	COG2610	gluconate transmembrane transporter activity
GCK71_RS20655	COG1609	Transcriptional regulator
GCK71_RS20660	COG1741	Belongs to the pirin family
GCK71_RS20685	COG0191	fructose-bisphosphate aldolase activity
GCK71_RS20700	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK71_RS20715	COG2081	HI0933 family
GCK71_RS20720	COG0306	phosphate transporter
GCK71_RS20735	COG0589	response to stress
GCK71_RS20755	COG0339	signal peptide processing
GCK71_RS20760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GCK71_RS20765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK71_RS20770	COG3835	regulator
GCK71_RS20780	COG2610	gluconate transmembrane transporter activity
GCK71_RS20785	COG1929	Belongs to the glycerate kinase type-1 family
GCK71_RS20810	COG1295	ribonuclease BN
GCK71_RS20815	COG2134	cdp-diacylglycerol pyrophosphatase
GCK71_RS20820	COG2982	Protein involved in outer membrane biogenesis
GCK71_RS20825	COG2200	EAL domain
GCK71_RS20830	COG1942	4-Oxalocrotonate Tautomerase
GCK71_RS20835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK71_RS20840	COG0612	Peptidase, M16
GCK71_RS20860	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK71_RS20865	COG2200	EAL domain
GCK71_RS20865	COG2199	diguanylate cyclase activity
GCK71_RS20870	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK71_RS20875	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK71_RS20880	COG4608	Belongs to the ABC transporter superfamily
GCK71_RS20885	COG0444	Belongs to the ABC transporter superfamily
GCK71_RS20890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK71_RS20895	COG0601	transmembrane transport
GCK71_RS20900	COG0747	negative chemotaxis
GCK71_RS20910	COG2831	hemolysin activation secretion protein
GCK71_RS20930	COG2271	Major facilitator Superfamily
GCK71_RS20955	COG2197	response regulator
GCK71_RS20960	COG2194	sulfuric ester hydrolase activity
GCK71_RS20975	COG2986	histidine ammonia-lyase
GCK71_RS21005	COG4607	ABC-type enterochelin transport system periplasmic component
GCK71_RS21015	COG4605	iron ion homeostasis
GCK71_RS21020	COG4604	ABC transporter, ATP-binding protein
GCK71_RS21070	COG0582	viral genome integration into host DNA
GCK71_RS21080	COG1609	Transcriptional regulator
GCK71_RS21080	COG2207	Transcriptional regulator
GCK71_RS21085	COG4214	carbohydrate transport
GCK71_RS21095	COG4213	ABC transporter substrate-binding protein
GCK71_RS21105	COG1070	Carbohydrate kinase
GCK71_RS21115	COG3121	Chaperone
GCK71_RS21130	COG3274	enterobacterial common antigen metabolic process
GCK71_RS21200	COG1175	transmembrane transport
GCK71_RS21205	COG3833	ABC-type maltose transport systems, permease component
GCK71_RS21220	COG0527	aspartate kinase activity
GCK71_RS21250	COG2224	Isocitrate lyase
GCK71_RS21255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GCK71_RS21305	COG2186	Transcriptional regulator
GCK71_RS21310	COG0477	Major facilitator Superfamily
GCK71_RS21325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK71_RS21355	COG1522	sequence-specific DNA binding
GCK71_RS21360	COG0716	FMN binding
GCK71_RS21380	COG3312	ion transport
GCK71_RS21440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCK71_RS21445	COG0573	inorganic phosphate transmembrane transporter activity
GCK71_RS21450	COG0581	inorganic phosphate transmembrane transporter activity
GCK71_RS21460	COG0704	Plays a role in the regulation of phosphate uptake
GCK71_RS21470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK71_RS21475	COG0765	amino acid transport
GCK71_RS21480	COG0765	amino acid transport
GCK71_RS21485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK71_RS21495	COG2252	PERMEase
GCK71_RS21525	COG0706	membrane insertase activity
GCK71_RS21540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GCK71_RS21605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GCK71_RS21615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK71_RS21765	COG3328	transposase activity
GCK71_RS21790	COG3344	reverse transcriptase
GCK71_RS21800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK71_RS21900	COG1475	DNA binding
GCK71_RS21915	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GCK71_RS21925	COG5301	cellulose 1,4-beta-cellobiosidase activity
GCK71_RS21925	COG5301	cellulose 1,4-beta-cellobiosidase activity
GCK71_RS21960	COG3941	tape measure
GCK71_RS22055	COG1475	DNA binding
GCK71_RS22060	COG1475	DNA binding
GCK71_RS22065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK71_RS22140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK71_RS22190	COG0515	serine threonine protein kinase
GCK71_RS22230	COG5599	Phosphatase
GCK71_RS22235	COG1317	bacterial-type flagellum organization
GCK71_RS22245	COG4669	(LipO)protein
GCK71_RS22280	COG1450	Type ii and iii secretion system protein
GCK71_RS22295	COG2207	Transcriptional regulator
GCK71_RS22305	COG4792	protein secretion
GCK71_RS22310	COG4791	protein targeting
GCK71_RS22315	COG4794	Type iii secretion
GCK71_RS22320	COG4790	Type iii secretion
GCK71_RS22370	COG4789	Type iii secretion
GCK71_RS22390	COG0457	Tetratricopeptide repeat
GCK71_RS22420	COG4886	Leucine-rich repeat (LRR) protein
GCK71_RS22430	COG3328	transposase activity
GCK71_RS22455	COG3177	Filamentation induced by cAMP protein fic
GCK71_RS22510	COG3609	addiction module antidote protein, CC2985 family
GCK71_RS22645	COG4683	PFAM Phage derived protein Gp49-like (DUF891)