locus-tag	class	description
GCK70_RS00010	COG0592	DNA-directed DNA polymerase activity
GCK70_RS00020	COG0187	DNA topoisomerase II activity
GCK70_RS00025	COG0561	phosphatase activity
GCK70_RS00045	COG2423	ornithine cyclodeaminase activity
GCK70_RS00050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GCK70_RS00065	COG5645	(Lipo)protein
GCK70_RS00085	COG3977	Valine--pyruvate aminotransferase
GCK70_RS00105	COG0366	Alpha amylase catalytic
GCK70_RS00125	COG2885	chlorophyll binding
GCK70_RS00135	COG2818	Glycosylase
GCK70_RS00160	COG2213	PTS system mannitol-specific
GCK70_RS00160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_RS00170	COG3722	fumarate hydratase activity
GCK70_RS00195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GCK70_RS00210	COG0437	4 iron, 4 sulfur cluster binding
GCK70_RS00215	COG2864	formate dehydrogenase
GCK70_RS00230	COG3276	selenocysteine insertion sequence binding
GCK70_RS00290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GCK70_RS00305	COG1629	transport
GCK70_RS00330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK70_RS00335	COG0678	peroxiredoxin activity
GCK70_RS00335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK70_RS00415	COG1879	ABC-type sugar transport system periplasmic component
GCK70_RS00420	COG1129	ABC transporter
GCK70_RS00425	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS00430	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS00440	COG3085	chromosome segregation
GCK70_RS00465	COG3978	acetolactate synthase activity
GCK70_RS00470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK70_RS00515	COG0583	DNA-binding transcription factor activity
GCK70_RS00555	COG3121	Chaperone
GCK70_RS00570	COG3121	Chaperone
GCK70_RS00585	COG3328	transposase activity
GCK70_RS00595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK70_RS00620	COG3118	belongs to the thioredoxin family
GCK70_RS00625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GCK70_RS00630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GCK70_RS00635	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK70_RS00640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GCK70_RS00645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GCK70_RS00650	COG1088	dTDP-glucose 4,6-dehydratase activity
GCK70_RS00655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GCK70_RS00660	COG0456	acetyltransferase
GCK70_RS00665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GCK70_RS00670	COG2244	polysaccharide biosynthetic process
GCK70_RS00690	COG1113	amino acid transport
GCK70_RS00725	COG3071	HemY protein
GCK70_RS00730	COG2959	enzyme of heme biosynthesis
GCK70_RS00735	COG1587	Uroporphyrinogen-III synthase
GCK70_RS00750	COG3072	Adenylate cyclase
GCK70_RS00770	COG3159	Protein conserved in bacteria
GCK70_RS00775	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GCK70_RS00780	COG1011	Hydrolase
GCK70_RS00785	COG0210	DNA helicase
GCK70_RS00795	COG5441	Belongs to the UPF0261 family
GCK70_RS00800	COG5564	TIM-barrel signal transduction protein
GCK70_RS00815	COG2050	protein possibly involved in aromatic compounds catabolism
GCK70_RS00820	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GCK70_RS00825	COG0514	ATP-dependent DNA helicase (RecQ)
GCK70_RS00830	COG1280	lysine exporter protein (LysE YggA)
GCK70_RS00835	COG1280	lysine exporter protein (LysE YggA)
GCK70_RS00840	COG2267	carboxylic ester hydrolase activity
GCK70_RS00845	COG0561	phosphatase activity
GCK70_RS00855	COG0584	glycerophosphoryl diester phosphodiesterase
GCK70_RS00870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK70_RS00880	COG0247	lactate metabolic process
GCK70_RS00890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GCK70_RS00905	COG3714	YhhN family
GCK70_RS00920	COG3776	membrane
GCK70_RS00925	COG0742	ribosomal rna small subunit methyltransferase
GCK70_RS00935	COG0552	protein localization to endoplasmic reticulum
GCK70_RS00935	COG0552	protein localization to endoplasmic reticulum
GCK70_RS00940	COG2884	Cell division ATP-binding protein ftsE
GCK70_RS00945	COG2177	Part of the ABC transporter FtsEX involved in
GCK70_RS00965	COG0683	leucine binding
GCK70_RS00975	COG4177	L-phenylalanine transmembrane transporter activity
GCK70_RS00985	COG0410	ABC transporter
GCK70_RS01000	COG3328	transposase activity
GCK70_RS01050	COG0584	glycerophosphoryl diester phosphodiesterase
GCK70_RS01055	COG0679	Auxin Efflux Carrier
GCK70_RS01060	COG0697	spore germination
GCK70_RS01065	COG0583	DNA-binding transcription factor activity
GCK70_RS01075	COG0412	Dienelactone hydrolase
GCK70_RS01090	COG1966	Carbon starvation protein
GCK70_RS01095	COG0586	Pfam SNARE associated Golgi protein
GCK70_RS01100	COG1322	Protein conserved in bacteria
GCK70_RS01120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK70_RS01130	COG0805	protein transport
GCK70_RS01165	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GCK70_RS01190	COG1739	Uncharacterized protein family UPF0029
GCK70_RS01205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GCK70_RS01210	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GCK70_RS01245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GCK70_RS01305	COG0250	Participates in transcription elongation, termination and antitermination
GCK70_RS01365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GCK70_RS01400	COG1515	deoxyribonuclease V activity
GCK70_RS01420	COG0151	Belongs to the GarS family
GCK70_RS01495	COG3162	membrane
GCK70_RS01505	COG1301	dicarboxylic acid transport
GCK70_RS01615	COG2391	methyltransferase activity
GCK70_RS01620	COG0425	Belongs to the sulfur carrier protein TusA family
GCK70_RS01625	COG0583	DNA-binding transcription factor activity
GCK70_RS01630	COG0814	amino acid
GCK70_RS01635	COG0626	cystathionine gamma-synthase activity
GCK70_RS01645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_RS01650	COG4558	Periplasmic binding protein
GCK70_RS01655	COG3720	iron ion transport
GCK70_RS01670	COG0702	epimerase
GCK70_RS01675	COG3721	Heme iron utilization protein
GCK70_RS01700	COG1358	cellular component organization or biogenesis
GCK70_RS01760	COG3121	Chaperone
GCK70_RS01815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GCK70_RS01825	COG0735	belongs to the Fur family
GCK70_RS01830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK70_RS01855	COG1448	Aminotransferase
GCK70_RS01860	COG2315	Protein conserved in bacteria
GCK70_RS01865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GCK70_RS01870	COG0629	single-stranded DNA binding
GCK70_RS01880	COG1454	alcohol dehydrogenase
GCK70_RS01950	COG1309	transcriptional regulator
GCK70_RS01960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_RS01960	COG0493	'glutamate synthase
GCK70_RS01965	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_RS01970	COG3383	formate dehydrogenase (NAD+) activity
GCK70_RS01985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GCK70_RS02035	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GCK70_RS02045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GCK70_RS02050	COG1053	succinate dehydrogenase
GCK70_RS02065	COG3264	Mechanosensitive ion channel
GCK70_RS02065	COG1511	domain protein
GCK70_RS02085	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GCK70_RS02105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GCK70_RS02110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GCK70_RS02110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GCK70_RS02115	COG0802	atpase or kinase
GCK70_RS02120	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK70_RS02140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GCK70_RS02145	COG0330	HflC and HflK could
GCK70_RS02150	COG0330	HflC and HflK could
GCK70_RS02155	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GCK70_RS02170	COG0557	exoribonuclease II activity
GCK70_RS02175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK70_RS02180	COG1960	acyl-CoA dehydrogenase activity
GCK70_RS02185	COG3650	response to hydrogen peroxide
GCK70_RS02205	COG1073	alpha beta
GCK70_RS02215	COG0360	Binds together with S18 to 16S ribosomal RNA
GCK70_RS02225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GCK70_RS02245	COG3061	Opacity-associated protein A
GCK70_RS02250	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK70_RS02260	COG0737	Belongs to the 5'-nucleotidase family
GCK70_RS02270	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GCK70_RS02280	COG1253	flavin adenine dinucleotide binding
GCK70_RS02290	COG0729	surface antigen
GCK70_RS02295	COG2911	Protein conserved in bacteria
GCK70_RS02300	COG2105	PFAM AIG2 family protein
GCK70_RS02305	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GCK70_RS02310	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GCK70_RS02315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GCK70_RS02340	COG3423	Transcriptional regulator
GCK70_RS02350	COG0142	geranyltranstransferase activity
GCK70_RS02365	COG0697	spore germination
GCK70_RS02375	COG0642	Histidine kinase
GCK70_RS02380	COG0745	RESPONSE REGULATOR receiver
GCK70_RS02385	COG2027	D-alanyl-D-alanine carboxypeptidase
GCK70_RS02395	COG1534	Rna-binding protein
GCK70_RS02410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GCK70_RS02420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GCK70_RS02440	COG0195	Participates in both transcription termination and antitermination
GCK70_RS02485	COG0513	Belongs to the DEAD box helicase family
GCK70_RS02510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GCK70_RS02520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK70_RS02530	COG0826	peptidase U32
GCK70_RS02535	COG0826	peptidase U32
GCK70_RS02545	COG3154	lipid carrier protein
GCK70_RS02550	COG3153	acetyltransferase
GCK70_RS02570	COG1653	transport
GCK70_RS02575	COG1175	transmembrane transport
GCK70_RS02580	COG0395	ABC-type sugar transport system, permease component
GCK70_RS02585	COG3842	ATPase activity
GCK70_RS02600	COG0702	epimerase
GCK70_RS02605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GCK70_RS02610	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GCK70_RS02615	COG3454	Phosphonate metabolism
GCK70_RS02620	COG4778	phosphonate C-P lyase system protein PhnL
GCK70_RS02625	COG4107	phosphonate C-P lyase system protein PhnK
GCK70_RS02630	COG3627	carbon phosphorus lyase activity
GCK70_RS02635	COG3626	phosphonate metabolism
GCK70_RS02640	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GCK70_RS02645	COG3624	Phosphonate C-P lyase system protein PhnG
GCK70_RS02650	COG2188	Transcriptional regulator
GCK70_RS02665	COG4608	Belongs to the ABC transporter superfamily
GCK70_RS02670	COG0444	Belongs to the ABC transporter superfamily
GCK70_RS02675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK70_RS02680	COG0601	transmembrane transport
GCK70_RS02690	COG2731	YhcH YjgK YiaL family protein
GCK70_RS02700	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GCK70_RS02710	COG0525	valine-tRNA ligase activity
GCK70_RS02715	COG2927	DNA polymerase III (CHI subunit)
GCK70_RS02725	COG0795	lipopolysaccharide-transporting ATPase activity
GCK70_RS02730	COG0795	lipopolysaccharide-transporting ATPase activity
GCK70_RS02740	COG0582	viral genome integration into host DNA
GCK70_RS02795	COG1459	type II secretion system
GCK70_RS02800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCK70_RS02805	COG4969	Belongs to the N-Me-Phe pilin family
GCK70_RS02815	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK70_RS02820	COG3725	Membrane protein required for beta-lactamase induction
GCK70_RS02825	COG1113	amino acid transport
GCK70_RS02835	COG2186	Transcriptional regulator
GCK70_RS02840	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GCK70_RS02845	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK70_RS02850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK70_RS02860	COG1049	propionate catabolic process, 2-methylcitrate cycle
GCK70_RS02870	COG0697	spore germination
GCK70_RS02890	COG2132	Multicopper oxidase
GCK70_RS02895	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GCK70_RS02900	COG0288	reversible hydration of carbon dioxide
GCK70_RS02905	COG1131	(ABC) transporter
GCK70_RS02910	COG0842	Transport permease protein
GCK70_RS02935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GCK70_RS02940	COG0617	tRNA 3'-terminal CCA addition
GCK70_RS02945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GCK70_RS02965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GCK70_RS02970	COG1643	Atp-dependent helicase
GCK70_RS02975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GCK70_RS02980	COG1120	ATPase activity
GCK70_RS02985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK70_RS02990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_RS03010	COG2860	membrane
GCK70_RS03030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK70_RS03035	COG2205	protein histidine kinase activity
GCK70_RS03035	COG4999	Histidine kinase
GCK70_RS03035	COG3850	Histidine kinase
GCK70_RS03035	COG3437	response regulator, receiver
GCK70_RS03045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GCK70_RS03050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK70_RS03055	COG3956	TIGRFAM MazG family protein
GCK70_RS03075	COG0602	queuosine metabolic process
GCK70_RS03080	COG0720	synthase
GCK70_RS03135	COG0529	Catalyzes the synthesis of activated sulfate
GCK70_RS03175	COG4942	peptidase
GCK70_RS03175	COG1388	LysM domain
GCK70_RS03180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GCK70_RS03190	COG0698	ribose 5-phosphate isomerase
GCK70_RS03195	COG1063	alcohol dehydrogenase
GCK70_RS03200	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS03205	COG2376	Dihydroxyacetone kinase
GCK70_RS03220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GCK70_RS03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_RS03245	COG1858	cytochrome C peroxidase
GCK70_RS03255	COG4771	TonB-dependent receptor
GCK70_RS03265	COG0024	Methionine aminopeptidase
GCK70_RS03275	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK70_RS03275	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GCK70_RS03280	COG1070	Carbohydrate kinase
GCK70_RS03285	COG3623	hexulose-6-phosphate isomerase
GCK70_RS03290	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS03295	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS03300	COG1129	ABC transporter
GCK70_RS03315	COG1349	DNA-binding transcription factor activity
GCK70_RS03320	COG0235	Class ii aldolase
GCK70_RS03325	COG0243	molybdopterin cofactor binding
GCK70_RS03330	COG0437	4 iron, 4 sulfur cluster binding
GCK70_RS03335	COG3302	dmso reductase anchor subunit
GCK70_RS03340	COG3381	protein complex oligomerization
GCK70_RS03345	COG3038	cytochrome b561
GCK70_RS03350	COG3783	Cytochrome b(562)
GCK70_RS03360	COG1879	ABC-type sugar transport system periplasmic component
GCK70_RS03370	COG1129	ABC transporter
GCK70_RS03375	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS03380	COG3959	Transketolase, thiamine diphosphate binding domain
GCK70_RS03385	COG3958	Transketolase
GCK70_RS03390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK70_RS03435	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GCK70_RS03465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK70_RS03470	COG1238	metal cluster binding
GCK70_RS03475	COG2918	glutathione biosynthetic process
GCK70_RS03490	COG4536	flavin adenine dinucleotide binding
GCK70_RS03495	COG4137	Cytochrome C assembly protein
GCK70_RS03500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GCK70_RS03530	COG3137	Salt-induced outer membrane protein
GCK70_RS03540	COG3279	Response regulator of the LytR AlgR family
GCK70_RS03545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK70_RS03550	COG1605	Chorismate mutase
GCK70_RS03550	COG0287	Prephenate dehydrogenase
GCK70_RS03580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GCK70_RS03585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK70_RS03595	COG0564	pseudouridine synthase activity
GCK70_RS03605	COG0542	response to heat
GCK70_RS03645	COG5544	Lipoprotein
GCK70_RS03650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK70_RS03655	COG1042	CoA-binding domain protein
GCK70_RS03655	COG0045	succinate-CoA ligase (ADP-forming) activity
GCK70_RS03655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK70_RS03660	COG3148	PFAM DTW domain containing protein
GCK70_RS03665	COG3118	belongs to the thioredoxin family
GCK70_RS03670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK70_RS03675	COG2814	Major facilitator Superfamily
GCK70_RS03680	COG1566	PFAM secretion protein HlyD family protein
GCK70_RS03685	COG1846	Transcriptional regulator
GCK70_RS03695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GCK70_RS03700	COG2814	Major facilitator Superfamily
GCK70_RS03740	COG0765	amino acid transport
GCK70_RS03750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK70_RS03765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GCK70_RS03790	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
GCK70_RS03800	COG1960	acyl-CoA dehydrogenase activity
GCK70_RS03810	COG0121	glutamine amidotransferase
GCK70_RS03815	COG3034	peptidoglycan biosynthetic process
GCK70_RS03830	COG1805	sodium ion transport
GCK70_RS03835	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GCK70_RS03855	COG1477	protein flavinylation
GCK70_RS03875	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK70_RS03880	COG0583	DNA-binding transcription factor activity
GCK70_RS03930	COG2226	methyltransferase
GCK70_RS03960	COG1940	carbohydrate kinase activity
GCK70_RS03965	COG0419	ATPase involved in DNA repair
GCK70_RS03970	COG0420	3'-5' exonuclease activity
GCK70_RS03975	COG0745	RESPONSE REGULATOR receiver
GCK70_RS03980	COG5002	protein histidine kinase activity
GCK70_RS04000	COG0366	Alpha amylase catalytic
GCK70_RS04030	COG0450	alkyl hydroperoxide reductase
GCK70_RS04050	COG1862	Preprotein translocase
GCK70_RS04055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK70_RS04060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GCK70_RS04095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK70_RS04095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GCK70_RS04110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GCK70_RS04115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GCK70_RS04130	COG0142	geranyltranstransferase activity
GCK70_RS04145	COG0693	protein deglycase activity
GCK70_RS04150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GCK70_RS04165	COG2814	Major facilitator Superfamily
GCK70_RS04175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GCK70_RS04180	COG1845	cytochrome c oxidase, subunit III
GCK70_RS04185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GCK70_RS04190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GCK70_RS04200	COG2223	nitrite transmembrane transporter activity
GCK70_RS04205	COG3056	Lipoprotein
GCK70_RS04210	COG0271	Belongs to the BolA IbaG family
GCK70_RS04235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GCK70_RS04240	COG0776	regulation of translation
GCK70_RS04245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GCK70_RS04250	COG1555	photosystem II stabilization
GCK70_RS04255	COG0824	Thioesterase
GCK70_RS04265	COG4533	DNA binding
GCK70_RS04280	COG1522	sequence-specific DNA binding
GCK70_RS04285	COG1132	(ABC) transporter
GCK70_RS04290	COG1132	(ABC) transporter
GCK70_RS04295	COG0347	Belongs to the P(II) protein family
GCK70_RS04300	COG0004	ammonium transporteR
GCK70_RS04305	COG1946	Acyl-CoA thioesterase
GCK70_RS04310	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GCK70_RS04315	COG3695	enzyme binding
GCK70_RS04340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK70_RS04350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK70_RS04355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_RS04360	COG1309	transcriptional regulator
GCK70_RS04365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GCK70_RS04370	COG3264	Mechanosensitive ion channel
GCK70_RS04370	COG1196	nuclear chromosome segregation
GCK70_RS04385	COG2832	Protein of unknown function (DUF454)
GCK70_RS04395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GCK70_RS04425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_RS04425	COG0543	2 iron, 2 sulfur cluster binding
GCK70_RS04450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_RS04495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_RS04515	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GCK70_RS04520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_RS04525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK70_RS04525	COG4651	solute:proton antiporter activity
GCK70_RS04530	COG2223	nitrite transmembrane transporter activity
GCK70_RS04545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GCK70_RS04550	COG3735	TraB family
GCK70_RS04555	COG2217	Heavy metal translocating P-type atpase
GCK70_RS04560	COG0789	Transcriptional regulator
GCK70_RS04565	COG1585	Membrane protein implicated in regulation of membrane protease activity
GCK70_RS04570	COG0330	HflC and HflK could
GCK70_RS04575	COG3118	belongs to the thioredoxin family
GCK70_RS04580	COG0300	oxidoreductase activity
GCK70_RS04585	COG2755	lipolytic protein G-D-S-L family
GCK70_RS04590	COG4181	ATPase activity
GCK70_RS04595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GCK70_RS04600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GCK70_RS04605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GCK70_RS04620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK70_RS04635	COG2501	S4 domain
GCK70_RS04670	COG0582	viral genome integration into host DNA
GCK70_RS04685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GCK70_RS04690	COG4589	Belongs to the CDS family
GCK70_RS04700	COG2267	carboxylic ester hydrolase activity
GCK70_RS04705	COG2453	phosphatase
GCK70_RS04705	COG0671	phosphoesterase, PA-phosphatase related
GCK70_RS04740	COG0667	Aldo Keto reductase
GCK70_RS04745	COG0656	L-ascorbic acid biosynthetic process
GCK70_RS04755	COG1472	Belongs to the glycosyl hydrolase 3 family
GCK70_RS04770	COG3328	transposase activity
GCK70_RS04825	COG3423	Transcriptional regulator
GCK70_RS04830	COG4953	penicillin-binding protein 1C
GCK70_RS04840	COG2373	Large extracellular alpha-helical protein
GCK70_RS04860	COG3962	Belongs to the TPP enzyme family
GCK70_RS04875	COG1129	ABC transporter
GCK70_RS04880	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS04885	COG0673	inositol 2-dehydrogenase activity
GCK70_RS04890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_RS04900	COG3718	enzyme involved in inositol metabolism
GCK70_RS04910	COG5265	(ABC) transporter
GCK70_RS04935	COG2197	response regulator
GCK70_RS04940	COG1278	Cold shock
GCK70_RS04950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK70_RS04955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GCK70_RS04980	COG1686	Belongs to the peptidase S11 family
GCK70_RS04985	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK70_RS04990	COG0772	Belongs to the SEDS family
GCK70_RS04995	COG0768	penicillin binding
GCK70_RS05005	COG0799	negative regulation of ribosome biogenesis
GCK70_RS05015	COG1466	dna polymerase III delta subunit
GCK70_RS05030	COG2888	peptidyl-tyrosine sulfation
GCK70_RS05035	COG1126	abc transporter atp-binding protein
GCK70_RS05040	COG0765	amino acid transport
GCK70_RS05045	COG0765	amino acid transport
GCK70_RS05055	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GCK70_RS05060	COG4535	Mg2 and Co2 transporter CorC
GCK70_RS05070	COG1702	phosphate starvation-inducible protein PhoH
GCK70_RS05075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GCK70_RS05080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK70_RS05120	COG0367	asparagine synthase
GCK70_RS05125	COG0647	UMP catabolic process
GCK70_RS05130	COG1846	Transcriptional regulator
GCK70_RS05130	COG1940	carbohydrate kinase activity
GCK70_RS05135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GCK70_RS05145	COG1263	PTS System
GCK70_RS05145	COG2190	(PTS) system
GCK70_RS05145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_RS05175	COG0735	belongs to the Fur family
GCK70_RS05195	COG0596	Alpha beta hydrolase
GCK70_RS05205	COG0582	viral genome integration into host DNA
GCK70_RS05235	COG2113	Glycine betaine
GCK70_RS05240	COG4176	ABC-type proline glycine betaine transport system permease component
GCK70_RS05245	COG4175	Glycine betaine
GCK70_RS05250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GCK70_RS05290	COG1278	Cold shock
GCK70_RS05295	COG0747	negative chemotaxis
GCK70_RS05305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK70_RS05310	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GCK70_RS05315	COG1124	(ABC) transporter
GCK70_RS05320	COG0831	urea catabolic process
GCK70_RS05345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GCK70_RS05355	COG4413	Urea transporter
GCK70_RS05360	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK70_RS05370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GCK70_RS05380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GCK70_RS05390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK70_RS05395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GCK70_RS05400	COG1447	Phosphotransferase system cellobiose-specific component IIA
GCK70_RS05405	COG1917	Cupin 2, conserved barrel domain protein
GCK70_RS05405	COG2169	Transcriptional regulator
GCK70_RS05425	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GCK70_RS05430	COG0033	Phosphoglucomutase
GCK70_RS05445	COG0745	RESPONSE REGULATOR receiver
GCK70_RS05450	COG2205	protein histidine kinase activity
GCK70_RS05490	COG3272	Protein of unknown function (DUF1722)
GCK70_RS05500	COG5212	phosphodiesterase
GCK70_RS05505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GCK70_RS05515	COG1984	allophanate hydrolase subunit 2
GCK70_RS05565	COG0513	Belongs to the DEAD box helicase family
GCK70_RS05575	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GCK70_RS05590	COG3026	antisigma factor binding
GCK70_RS05595	COG3086	response to oxidative stress
GCK70_RS05630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GCK70_RS05645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_RS05650	COG1737	Transcriptional regulator
GCK70_RS05660	COG0560	Phosphoserine phosphatase
GCK70_RS05710	COG2205	protein histidine kinase activity
GCK70_RS05715	COG3170	Tfp pilus assembly protein FimV
GCK70_RS05720	COG2204	response regulator
GCK70_RS05725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GCK70_RS05725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK70_RS05730	COG0347	Belongs to the P(II) protein family
GCK70_RS05740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_RS05740	COG1017	nitric oxide dioxygenase activity
GCK70_RS05760	COG2814	Major facilitator Superfamily
GCK70_RS05765	COG3711	transcriptional antiterminator
GCK70_RS05770	COG3683	transport system, periplasmic component
GCK70_RS05775	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GCK70_RS05795	COG1104	cysteine desulfurase activity
GCK70_RS05800	COG0822	iron-sulfur transferase activity
GCK70_RS05820	COG0443	Heat shock 70 kDa protein
GCK70_RS05825	COG0633	Ferredoxin
GCK70_RS05830	COG2975	iron-sulfur cluster assembly
GCK70_RS05855	COG3468	outer membrane autotransporter barrel domain protein
GCK70_RS05860	COG3468	outer membrane autotransporter barrel domain protein
GCK70_RS05905	COG2976	Protein conserved in bacteria
GCK70_RS05910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK70_RS05925	COG1645	bacterial-type flagellum-dependent swarming motility
GCK70_RS05935	COG0516	GMP reductase activity
GCK70_RS05935	COG0517	IMP dehydrogenase activity
GCK70_RS05985	COG3328	transposase activity
GCK70_RS06000	COG0351	phosphomethylpyrimidine kinase
GCK70_RS06025	COG0826	peptidase U32
GCK70_RS06030	COG3422	double-strand break repair
GCK70_RS06035	COG0745	RESPONSE REGULATOR receiver
GCK70_RS06065	COG3842	ATPase activity
GCK70_RS06075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GCK70_RS06085	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK70_RS06090	COG1177	transmembrane transport
GCK70_RS06095	COG0443	Heat shock 70 kDa protein
GCK70_RS06100	COG2239	Acts as a magnesium transporter
GCK70_RS06115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GCK70_RS06125	COG0581	inorganic phosphate transmembrane transporter activity
GCK70_RS06140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK70_RS06145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GCK70_RS06170	COG1393	Belongs to the ArsC family
GCK70_RS06175	COG4783	chaperone-mediated protein folding
GCK70_RS06180	COG0628	permease
GCK70_RS06195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GCK70_RS06200	COG2716	regulation of RNA biosynthetic process
GCK70_RS06210	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GCK70_RS06230	COG2321	neutral zinc metallopeptidase
GCK70_RS06255	COG1876	peptidase activity
GCK70_RS06265	COG1393	Belongs to the ArsC family
GCK70_RS06280	COG1175	transmembrane transport
GCK70_RS06295	COG3119	arylsulfatase activity
GCK70_RS06300	COG0641	radical SAM
GCK70_RS06305	COG1988	membrane-bound metal-dependent
GCK70_RS06315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK70_RS06325	COG2197	response regulator
GCK70_RS06330	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_RS06330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GCK70_RS06335	COG3062	negative regulation of establishment of protein localization
GCK70_RS06345	COG3043	anaerobic respiration
GCK70_RS06350	COG3005	denitrification pathway
GCK70_RS06395	COG3111	PFAM Bacterial OB fold (BOF) protein
GCK70_RS06405	COG2837	iron assimilation
GCK70_RS06410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GCK70_RS06420	COG4886	Leucine-rich repeat (LRR) protein
GCK70_RS06430	COG2731	YhcH YjgK YiaL family protein
GCK70_RS06440	COG1737	Transcriptional regulator
GCK70_RS06450	COG4150	thiosulfate binding
GCK70_RS06455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GCK70_RS06460	COG4208	sulfate ABC transporter
GCK70_RS06465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GCK70_RS06480	COG0745	RESPONSE REGULATOR receiver
GCK70_RS06485	COG5002	protein histidine kinase activity
GCK70_RS06485	COG3850	Histidine kinase
GCK70_RS06495	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GCK70_RS06515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GCK70_RS06530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_RS06535	COG0745	RESPONSE REGULATOR receiver
GCK70_RS06540	COG2205	protein histidine kinase activity
GCK70_RS06560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_RS06570	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GCK70_RS06585	COG3530	Putative quorum-sensing-regulated virulence factor
GCK70_RS06650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK70_RS06665	COG0667	Aldo Keto reductase
GCK70_RS06690	COG0436	Aminotransferase
GCK70_RS06700	COG3038	cytochrome b561
GCK70_RS06730	COG3381	protein complex oligomerization
GCK70_RS06735	COG3302	dmso reductase anchor subunit
GCK70_RS06740	COG0437	4 iron, 4 sulfur cluster binding
GCK70_RS06745	COG0243	molybdopterin cofactor binding
GCK70_RS06780	COG2951	lytic endotransglycosylase activity
GCK70_RS06840	COG3121	Chaperone
GCK70_RS06845	COG3188	usher protein
GCK70_RS06855	COG3328	transposase activity
GCK70_RS06860	COG3188	usher protein
GCK70_RS06950	COG2824	Alkylphosphonate utilization operon protein PhnA
GCK70_RS06960	COG1704	LemA family
GCK70_RS06980	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK70_RS06985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK70_RS06990	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GCK70_RS07000	COG1138	Cytochrome C-type biogenesis protein
GCK70_RS07005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GCK70_RS07010	COG4235	cytochrome complex assembly
GCK70_RS07010	COG3088	subunit of a heme lyase
GCK70_RS07015	COG3088	subunit of a heme lyase
GCK70_RS07015	COG4235	cytochrome complex assembly
GCK70_RS07030	COG3691	Protein conserved in bacteria
GCK70_RS07045	COG2062	phosphohistidine phosphatase, SixA
GCK70_RS07055	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK70_RS07070	COG0730	response to heat
GCK70_RS07075	COG3101	peptidyl-lysine hydroxylation
GCK70_RS07090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK70_RS07095	COG1794	racemase activity, acting on amino acids and derivatives
GCK70_RS07110	COG0697	spore germination
GCK70_RS07125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK70_RS07135	COG0586	Pfam SNARE associated Golgi protein
GCK70_RS07145	COG0285	dihydrofolate synthase activity
GCK70_RS07150	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GCK70_RS07155	COG1286	toxin biosynthetic process
GCK70_RS07160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GCK70_RS07170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_RS07175	COG4215	(ABC) transporter
GCK70_RS07180	COG4160	amino acid transport
GCK70_RS07185	COG4598	ABC transporter
GCK70_RS07190	COG1090	epimerase
GCK70_RS07205	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GCK70_RS07210	COG3037	sugar-specific permease SgaT UlaA
GCK70_RS07215	COG3328	transposase activity
GCK70_RS07235	COG1609	Transcriptional regulator
GCK70_RS07240	COG0857	belongs to the CobB CobQ family
GCK70_RS07240	COG0280	phosphate acetyltransferase
GCK70_RS07260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK70_RS07265	COG0471	metal ion transport
GCK70_RS07265	COG0490	domain, Protein
GCK70_RS07280	COG0436	Aminotransferase
GCK70_RS07285	COG0583	DNA-binding transcription factor activity
GCK70_RS07295	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK70_RS07315	COG1034	ATP synthesis coupled electron transport
GCK70_RS07330	COG0839	Belongs to the complex I subunit 6 family
GCK70_RS07340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GCK70_RS07345	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK70_RS07360	COG2731	YhcH YjgK YiaL family protein
GCK70_RS07365	COG3265	gluconokinase activity
GCK70_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS07375	COG1649	PFAM Uncharacterised BCR, COG1649
GCK70_RS07380	COG1609	Transcriptional regulator
GCK70_RS07385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK70_RS07400	COG0129	dihydroxy-acid dehydratase activity
GCK70_RS07415	COG4575	ribosome binding
GCK70_RS07425	COG1169	isochorismate synthase
GCK70_RS07440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GCK70_RS07455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GCK70_RS07500	COG1126	abc transporter atp-binding protein
GCK70_RS07505	COG0765	amino acid transport
GCK70_RS07510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_RS07540	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GCK70_RS07560	COG1063	alcohol dehydrogenase
GCK70_RS07565	COG1879	ABC-type sugar transport system periplasmic component
GCK70_RS07570	COG1129	ABC transporter
GCK70_RS07575	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS07580	COG1609	Transcriptional regulator
GCK70_RS07585	COG0583	DNA-binding transcription factor activity
GCK70_RS07590	COG0473	3-isopropylmalate dehydrogenase activity
GCK70_RS07600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK70_RS07605	COG4638	Rieske (2fe-2S)
GCK70_RS07610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_RS07615	COG2831	hemolysin activation secretion protein
GCK70_RS07620	COG3210	domain, Protein
GCK70_RS07640	COG3210	domain, Protein
GCK70_RS07660	COG3210	domain, Protein
GCK70_RS07665	COG3210	domain, Protein
GCK70_RS07675	COG3842	ATPase activity
GCK70_RS07685	COG1609	Transcriptional regulator
GCK70_RS07700	COG0395	ABC-type sugar transport system, permease component
GCK70_RS07705	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GCK70_RS07725	COG0668	transmembrane transport
GCK70_RS07730	COG1518	maintenance of DNA repeat elements
GCK70_RS07735	COG1203	CRISPR-associated helicase, Cas3
GCK70_RS07760	COG0667	Aldo Keto reductase
GCK70_RS07770	COG0477	Major facilitator Superfamily
GCK70_RS07780	COG0583	DNA-binding transcription factor activity
GCK70_RS07785	COG2771	luxR family
GCK70_RS07790	COG3916	Acyl-homoserine-lactone synthase
GCK70_RS07810	COG0628	permease
GCK70_RS07830	COG3328	transposase activity
GCK70_RS07855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GCK70_RS07870	COG3328	transposase activity
GCK70_RS07875	COG1530	ribonuclease E activity
GCK70_RS07880	COG0564	pseudouridine synthase activity
GCK70_RS07885	COG0424	maF-like protein
GCK70_RS07890	COG1399	metal-binding, possibly nucleic acid-binding protein
GCK70_RS07895	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GCK70_RS07925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK70_RS07935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GCK70_RS07940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GCK70_RS07950	COG0470	DNA polymerase III
GCK70_RS07955	COG0084	hydrolase, TatD family'
GCK70_RS07960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_RS07960	COG1263	PTS System
GCK70_RS07970	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GCK70_RS07975	COG0537	adenosine 5'-monophosphoramidase activity
GCK70_RS07980	COG5633	Lipoprotein
GCK70_RS07995	COG1472	Belongs to the glycosyl hydrolase 3 family
GCK70_RS08005	COG1252	NADH dehydrogenase
GCK70_RS08025	COG3328	transposase activity
GCK70_RS08035	COG3134	Outer membrane lipoprotein
GCK70_RS08040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GCK70_RS08045	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK70_RS08055	COG4591	ABC-type transport system involved in lipoprotein release permease component
GCK70_RS08060	COG1940	carbohydrate kinase activity
GCK70_RS08085	COG2850	peptidyl-arginine hydroxylation
GCK70_RS08095	COG0745	RESPONSE REGULATOR receiver
GCK70_RS08105	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GCK70_RS08125	COG1187	pseudouridine synthase activity
GCK70_RS08130	COG0538	isocitrate dehydrogenase activity
GCK70_RS08145	COG0840	transmembrane signaling receptor activity
GCK70_RS08150	COG0702	epimerase
GCK70_RS08155	COG1733	regulation of RNA biosynthetic process
GCK70_RS08175	COG1522	sequence-specific DNA binding
GCK70_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS08185	COG3321	synthase
GCK70_RS08185	COG0604	alcohol dehydrogenase
GCK70_RS08210	COG1285	pathogenesis
GCK70_RS08235	COG1360	Flagellar Motor Protein
GCK70_RS08240	COG0643	Histidine kinase
GCK70_RS08240	COG2198	Histidine kinase
GCK70_RS08245	COG0835	chemotaxis
GCK70_RS08250	COG2271	Major facilitator Superfamily
GCK70_RS08255	COG0251	oxidation-reduction process
GCK70_RS08265	COG2964	Protein conserved in bacteria
GCK70_RS08285	COG0840	transmembrane signaling receptor activity
GCK70_RS08290	COG0840	transmembrane signaling receptor activity
GCK70_RS08295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GCK70_RS08305	COG0745	RESPONSE REGULATOR receiver
GCK70_RS08310	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GCK70_RS08320	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK70_RS08330	COG5295	Hep Hag repeat protein
GCK70_RS08340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GCK70_RS08395	COG3121	Chaperone
GCK70_RS08415	COG3008	intermembrane lipid transfer
GCK70_RS08420	COG2995	paraquat-inducible protein a
GCK70_RS08425	COG1956	GAF domain-containing protein
GCK70_RS08435	COG0793	Belongs to the peptidase S41A family
GCK70_RS08450	COG3539	Fimbrial protein
GCK70_RS08455	COG3121	Chaperone
GCK70_RS08470	COG3121	Chaperone
GCK70_RS08475	COG2814	Major facilitator Superfamily
GCK70_RS08480	COG0823	Involved in the tonB-independent uptake of proteins
GCK70_RS08490	COG3023	N-Acetylmuramoyl-L-alanine amidase
GCK70_RS08495	COG1823	symporter activity
GCK70_RS08500	COG1988	membrane-bound metal-dependent
GCK70_RS08505	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK70_RS08510	COG1653	transport
GCK70_RS08515	COG3842	ATPase activity
GCK70_RS08520	COG0395	ABC-type sugar transport system, permease component
GCK70_RS08525	COG1175	transmembrane transport
GCK70_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS08545	COG1917	Cupin 2, conserved barrel domain protein
GCK70_RS08550	COG3328	transposase activity
GCK70_RS08555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK70_RS08565	COG3001	Fructosamine kinase
GCK70_RS08575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK70_RS08580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK70_RS08585	COG1121	(ABC) transporter
GCK70_RS08590	COG0803	Belongs to the bacterial solute-binding protein 9 family
GCK70_RS08615	COG4249	Peptidase C14 caspase catalytic subunit p20
GCK70_RS08650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GCK70_RS08650	COG0072	phenylalanine-tRNA ligase activity
GCK70_RS08655	COG0776	regulation of translation
GCK70_RS08670	COG0386	Belongs to the glutathione peroxidase family
GCK70_RS08720	COG0791	NLP P60 protein
GCK70_RS08745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK70_RS08745	COG0574	Belongs to the PEP-utilizing enzyme family
GCK70_RS08755	COG0628	permease
GCK70_RS08760	COG0277	FAD linked oxidase domain protein
GCK70_RS08760	COG0247	lactate metabolic process
GCK70_RS08765	COG2050	protein possibly involved in aromatic compounds catabolism
GCK70_RS08775	COG0316	Belongs to the HesB IscA family
GCK70_RS08780	COG0719	Fe-S assembly protein
GCK70_RS08785	COG0396	ATPase activity
GCK70_RS08790	COG0719	Fe-S assembly protein
GCK70_RS08805	COG1376	ErfK ybiS ycfS ynhG family protein
GCK70_RS08805	COG1388	LysM domain
GCK70_RS08855	COG0307	riboflavin synthase, alpha
GCK70_RS08860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GCK70_RS08865	COG2814	Major facilitator Superfamily
GCK70_RS08870	COG0583	DNA-binding transcription factor activity
GCK70_RS08890	COG0791	NLP P60 protein
GCK70_RS08900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GCK70_RS08910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GCK70_RS08915	COG0346	lactoylglutathione lyase activity
GCK70_RS08925	COG1902	pentaerythritol trinitrate reductase activity
GCK70_RS08930	COG1309	transcriptional regulator
GCK70_RS08935	COG2194	sulfuric ester hydrolase activity
GCK70_RS08940	COG3313	Fe-S protein
GCK70_RS08945	COG4989	oxidoreductase activity
GCK70_RS08960	COG3133	Outer membrane lipoprotein
GCK70_RS08970	COG3895	Periplasmic Protein
GCK70_RS08990	COG0625	glutathione transferase activity
GCK70_RS09005	COG3104	oligopeptide transport
GCK70_RS09010	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK70_RS09010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK70_RS09015	COG4172	Belongs to the ABC transporter superfamily
GCK70_RS09025	COG4171	peptide transport system, permease
GCK70_RS09030	COG4168	peptide transport system, permease
GCK70_RS09035	COG4166	transmembrane transport
GCK70_RS09050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GCK70_RS09055	COG1842	Phage shock protein A
GCK70_RS09065	COG1983	PspC domain protein
GCK70_RS09075	COG3106	COG3106 Predicted ATPase
GCK70_RS09085	COG5654	RES domain protein
GCK70_RS09090	COG5642	Protein of unknown function (DUF2384)
GCK70_RS09105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GCK70_RS09110	COG4948	Mandelate Racemase Muconate Lactonizing
GCK70_RS09115	COG2866	Carboxypeptidase
GCK70_RS09120	COG4166	transmembrane transport
GCK70_RS09140	COG0657	acetylesterase activity
GCK70_RS09150	COG0674	pyruvate-flavodoxin oxidoreductase activity
GCK70_RS09150	COG1013	pyruvate-flavodoxin oxidoreductase activity
GCK70_RS09150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GCK70_RS09150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GCK70_RS09160	COG1285	pathogenesis
GCK70_RS09165	COG3042	response to heat
GCK70_RS09170	COG3187	Heat shock protein
GCK70_RS09175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GCK70_RS09180	COG2911	Protein conserved in bacteria
GCK70_RS09190	COG3784	Protein of unknown function (DUF1318)
GCK70_RS09195	COG0246	Mannitol dehydrogenase
GCK70_RS09200	COG2390	Transcriptional regulator
GCK70_RS09210	COG1643	Atp-dependent helicase
GCK70_RS09225	COG3591	Belongs to the peptidase S1B family
GCK70_RS09240	COG3038	cytochrome b561
GCK70_RS09265	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GCK70_RS09270	COG2205	protein histidine kinase activity
GCK70_RS09275	COG0745	RESPONSE REGULATOR receiver
GCK70_RS09285	COG0531	amino acid
GCK70_RS09300	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GCK70_RS09305	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GCK70_RS09310	COG0589	response to stress
GCK70_RS09315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GCK70_RS09320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK70_RS09335	COG1011	Hydrolase
GCK70_RS09340	COG0440	acetolactate synthase activity
GCK70_RS09345	COG0028	Belongs to the TPP enzyme family
GCK70_RS09375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GCK70_RS09385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK70_RS09405	COG1609	Transcriptional regulator
GCK70_RS09415	COG0038	chloride channel
GCK70_RS09420	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GCK70_RS09425	COG1940	carbohydrate kinase activity
GCK70_RS09430	COG0583	DNA-binding transcription factor activity
GCK70_RS09435	COG2814	Major facilitator Superfamily
GCK70_RS09445	COG0114	fumarate hydratase activity
GCK70_RS09455	COG5339	Protein conserved in bacteria
GCK70_RS09465	COG0385	Bile acid
GCK70_RS09470	COG0673	inositol 2-dehydrogenase activity
GCK70_RS09480	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS09485	COG1129	ABC transporter
GCK70_RS09490	COG1879	ABC-type sugar transport system periplasmic component
GCK70_RS09505	COG2274	protein secretion by the type I secretion system
GCK70_RS09510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_RS09545	COG2207	Transcriptional regulator
GCK70_RS09545	COG3708	Transcriptional regulator
GCK70_RS09550	COG4658	electron transport chain
GCK70_RS09555	COG4659	FMN binding
GCK70_RS09565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GCK70_RS09570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_RS09575	COG2271	Major facilitator Superfamily
GCK70_RS09585	COG1966	Carbon starvation protein
GCK70_RS09590	COG2879	small protein
GCK70_RS09595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GCK70_RS09615	COG0023	Translation Initiation Factor
GCK70_RS09630	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GCK70_RS09635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GCK70_RS09640	COG0671	phosphoesterase, PA-phosphatase related
GCK70_RS09650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GCK70_RS09660	COG0583	DNA-binding transcription factor activity
GCK70_RS09680	COG0616	signal peptide processing
GCK70_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS09695	COG1187	pseudouridine synthase activity
GCK70_RS09700	COG0009	L-threonylcarbamoyladenylate synthase
GCK70_RS09725	COG0512	Glutamine amidotransferase of anthranilate synthase
GCK70_RS09735	COG0134	indole-3-glycerol-phosphate synthase activity
GCK70_RS09735	COG0135	phosphoribosylanthranilate isomerase activity
GCK70_RS09755	COG3047	cAMP biosynthetic process
GCK70_RS09795	COG3328	transposase activity
GCK70_RS09800	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GCK70_RS09805	COG2350	Protein conserved in bacteria
GCK70_RS09845	COG4608	Belongs to the ABC transporter superfamily
GCK70_RS09850	COG0444	Belongs to the ABC transporter superfamily
GCK70_RS09855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK70_RS09860	COG0601	transmembrane transport
GCK70_RS09870	COG2095	MarC family integral membrane protein
GCK70_RS09880	COG1454	alcohol dehydrogenase
GCK70_RS09880	COG1012	belongs to the aldehyde dehydrogenase family
GCK70_RS09915	COG0745	RESPONSE REGULATOR receiver
GCK70_RS09925	COG0788	formyltetrahydrofolate deformylase activity
GCK70_RS09930	COG3328	transposase activity
GCK70_RS09950	COG3328	transposase activity
GCK70_RS09955	COG0583	DNA-binding transcription factor activity
GCK70_RS09960	COG0708	Exodeoxyribonuclease III
GCK70_RS09965	COG0494	nUDIX hydrolase
GCK70_RS09975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GCK70_RS09980	COG0709	Synthesizes selenophosphate from selenide and ATP
GCK70_RS09985	COG0778	Nitroreductase
GCK70_RS09990	COG0616	signal peptide processing
GCK70_RS09995	COG0252	asparaginase activity
GCK70_RS10000	COG1335	isochorismatase
GCK70_RS10005	COG3139	Protein of unknown function (DUF1315)
GCK70_RS10025	COG3713	MltA-interacting MipA family protein
GCK70_RS10035	COG2766	serine protein kinase
GCK70_RS10050	COG0583	DNA-binding transcription factor activity
GCK70_RS10060	COG2814	Major facilitator Superfamily
GCK70_RS10070	COG2719	SpoVR family
GCK70_RS10105	COG1104	cysteine desulfurase activity
GCK70_RS10115	COG3328	transposase activity
GCK70_RS10285	COG3328	transposase activity
GCK70_RS10380	COG0582	viral genome integration into host DNA
GCK70_RS10390	COG0179	Fumarylacetoacetate (FAA) hydrolase
GCK70_RS10395	COG2951	lytic endotransglycosylase activity
GCK70_RS10410	COG2894	cell division
GCK70_RS10415	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GCK70_RS10420	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GCK70_RS10425	COG0318	PFAM AMP-dependent synthetase and ligase
GCK70_RS10435	COG3065	identical protein binding
GCK70_RS10445	COG1199	ATP-dependent helicase activity
GCK70_RS10450	COG0251	oxidation-reduction process
GCK70_RS10465	COG0800	Aldolase
GCK70_RS10475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GCK70_RS10480	COG1737	Transcriptional regulator
GCK70_RS10485	COG0469	pyruvate kinase activity
GCK70_RS10495	COG1560	Kdo2-lipid A biosynthetic process
GCK70_RS10500	COG0739	heme binding
GCK70_RS10505	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GCK70_RS10515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GCK70_RS10545	COG0494	nUDIX hydrolase
GCK70_RS10555	COG1801	Protein of unknown function DUF72
GCK70_RS10560	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GCK70_RS10580	COG3102	Protein conserved in bacteria
GCK70_RS10600	COG0728	peptidoglycan biosynthetic process
GCK70_RS10610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GCK70_RS10625	COG3381	protein complex oligomerization
GCK70_RS10640	COG1940	carbohydrate kinase activity
GCK70_RS10645	COG0584	glycerophosphoryl diester phosphodiesterase
GCK70_RS10675	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK70_RS10680	COG3833	ABC-type maltose transport systems, permease component
GCK70_RS10705	COG0659	secondary active sulfate transmembrane transporter activity
GCK70_RS10725	COG2890	protein-(glutamine-N5) methyltransferase activity
GCK70_RS10750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GCK70_RS10765	COG0012	GTP binding
GCK70_RS10820	COG5002	protein histidine kinase activity
GCK70_RS10860	COG0500	methyltransferase
GCK70_RS10885	COG3328	transposase activity
GCK70_RS10930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_RS10950	COG0402	S-adenosylhomocysteine deaminase activity
GCK70_RS11005	COG3842	ATPase activity
GCK70_RS11010	COG0395	ABC-type sugar transport system, permease component
GCK70_RS11015	COG1175	transmembrane transport
GCK70_RS11025	COG0673	inositol 2-dehydrogenase activity
GCK70_RS11035	COG2188	Transcriptional regulator
GCK70_RS11180	COG2197	response regulator
GCK70_RS11190	COG3136	membrane protein required for alginate biosynthesis
GCK70_RS11215	COG1113	amino acid transport
GCK70_RS11235	COG2822	iron ion transport
GCK70_RS11240	COG0672	)-iron permease
GCK70_RS11255	COG0506	proline dehydrogenase activity
GCK70_RS11255	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK70_RS11255	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GCK70_RS11270	COG1126	abc transporter atp-binding protein
GCK70_RS11275	COG0765	amino acid transport
GCK70_RS11280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_RS11295	COG1191	sigma factor activity
GCK70_RS11330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GCK70_RS11335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GCK70_RS11340	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GCK70_RS11360	COG1677	Flagellar hook-basal body complex protein FliE
GCK70_RS11380	COG1157	protein secretion by the type III secretion system
GCK70_RS11395	COG1580	Controls the rotational direction of flagella during chemotaxis
GCK70_RS11420	COG1987	bacterial-type flagellum assembly
GCK70_RS11440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_RS11445	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS11450	COG1129	ABC transporter
GCK70_RS11460	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS11465	COG3347	Dehydrogenase
GCK70_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS11470	COG2390	Transcriptional regulator
GCK70_RS11480	COG1256	bacterial-type flagellum assembly
GCK70_RS11520	COG1558	bacterial-type flagellum-dependent cell motility
GCK70_RS11525	COG1815	bacterial-type flagellum-dependent cell motility
GCK70_RS11535	COG2747	anti-sigma28 factor FlgM
GCK70_RS11540	COG3418	PFAM FlgN family protein
GCK70_RS11565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK70_RS11570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK70_RS11600	COG2372	response to copper ion
GCK70_RS11605	COG1528	Iron-storage protein
GCK70_RS11620	COG1770	oligopeptidase
GCK70_RS11635	COG3141	response to X-ray
GCK70_RS11640	COG0513	Belongs to the DEAD box helicase family
GCK70_RS11665	COG1760	l-serine dehydratase
GCK70_RS11670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GCK70_RS11675	COG2368	4-hydroxyphenylacetate
GCK70_RS11690	COG3971	2-oxopent-4-enoate hydratase activity
GCK70_RS11700	COG3384	dioxygenase
GCK70_RS11705	COG1012	belongs to the aldehyde dehydrogenase family
GCK70_RS11720	COG1846	Transcriptional regulator
GCK70_RS11730	COG1253	flavin adenine dinucleotide binding
GCK70_RS11735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_RS11735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_RS11740	COG3715	PTS system
GCK70_RS11745	COG3716	PTS system mannose fructose sorbose family IID component
GCK70_RS11765	COG5002	protein histidine kinase activity
GCK70_RS11765	COG3447	MASE1 domain protein
GCK70_RS11765	COG5001	Diguanylate cyclase
GCK70_RS11775	COG2226	methyltransferase
GCK70_RS11780	COG1496	oxidoreductase activity
GCK70_RS11805	COG1113	amino acid transport
GCK70_RS11845	COG2207	Transcriptional regulator
GCK70_RS11860	COG1132	(ABC) transporter
GCK70_RS11915	COG3328	transposase activity
GCK70_RS11920	COG2223	nitrite transmembrane transporter activity
GCK70_RS11945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GCK70_RS11970	COG3122	Protein conserved in bacteria
GCK70_RS11990	COG0534	Mate efflux family protein
GCK70_RS12010	COG4948	Mandelate Racemase Muconate Lactonizing
GCK70_RS12020	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS12025	COG3011	Protein conserved in bacteria
GCK70_RS12030	COG2271	Major facilitator Superfamily
GCK70_RS12035	COG1470	cell adhesion involved in biofilm formation
GCK70_RS12035	COG1388	LysM domain
GCK70_RS12040	COG3328	transposase activity
GCK70_RS12055	COG2925	Exonuclease
GCK70_RS12065	COG0531	amino acid
GCK70_RS12075	COG0371	Dehydrogenase
GCK70_RS12080	COG1129	ABC transporter
GCK70_RS12085	COG1129	ABC transporter
GCK70_RS12090	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS12095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_RS12110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GCK70_RS12120	COG0131	Imidazoleglycerol-phosphate dehydratase
GCK70_RS12120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK70_RS12140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GCK70_RS12140	COG0140	phosphoribosyl-ATP diphosphatase activity
GCK70_RS12150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK70_RS12155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GCK70_RS12170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GCK70_RS12175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_RS12180	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_RS12185	COG1120	ATPase activity
GCK70_RS12200	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GCK70_RS12205	COG0076	glutamate decarboxylase activity
GCK70_RS12210	COG4114	ferric iron reductase
GCK70_RS12215	COG1253	flavin adenine dinucleotide binding
GCK70_RS12220	COG2982	Protein involved in outer membrane biogenesis
GCK70_RS12235	COG0489	protein tyrosine kinase activity
GCK70_RS12265	COG2814	Major facilitator Superfamily
GCK70_RS12275	COG1346	cytolysis
GCK70_RS12290	COG2949	membrane
GCK70_RS12295	COG4211	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS12310	COG2311	Membrane
GCK70_RS12320	COG0477	Major facilitator Superfamily
GCK70_RS12325	COG0583	DNA-binding transcription factor activity
GCK70_RS12355	COG1136	(ABC) transporter
GCK70_RS12365	COG0303	'Molybdopterin
GCK70_RS12375	COG3328	transposase activity
GCK70_RS12385	COG0488	(ABC) transporter
GCK70_RS12515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GCK70_RS12520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GCK70_RS12530	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS12535	COG1024	Enoyl-CoA hydratase
GCK70_RS12545	COG3425	synthase
GCK70_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS12555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GCK70_RS12560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GCK70_RS12570	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS12595	COG2920	part of a sulfur-relay system
GCK70_RS12615	COG1832	CoA-binding protein
GCK70_RS12630	COG0210	DNA helicase
GCK70_RS12635	COG3304	Inner membrane component domain
GCK70_RS12640	COG1289	transmembrane transporter activity
GCK70_RS12645	COG3070	regulator of competence-specific genes
GCK70_RS12670	COG1067	ATP-dependent peptidase activity
GCK70_RS12715	COG3130	regulation of translation
GCK70_RS12725	COG3009	Protein conserved in bacteria
GCK70_RS12735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK70_RS12735	COG3008	intermembrane lipid transfer
GCK70_RS12740	COG2995	paraquat-inducible protein a
GCK70_RS12755	COG3217	Mosc domain protein beta barrel domain protein
GCK70_RS12755	COG0633	Ferredoxin
GCK70_RS12770	COG0308	aminopeptidase N
GCK70_RS12790	COG1448	Aminotransferase
GCK70_RS12800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK70_RS12805	COG3108	Peptidase M15
GCK70_RS12810	COG2989	Protein conserved in bacteria
GCK70_RS12835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GCK70_RS12850	COG3173	Aminoglycoside phosphotransferase
GCK70_RS12870	COG1278	Cold shock
GCK70_RS12880	COG5383	Protein conserved in bacteria
GCK70_RS12895	COG2333	competence protein COMEC
GCK70_RS12895	COG0658	competence protein
GCK70_RS12910	COG0539	negative regulation of cytoplasmic translation
GCK70_RS12935	COG5295	Hep Hag repeat protein
GCK70_RS12935	COG5295	Hep Hag repeat protein
GCK70_RS12940	COG0252	asparaginase activity
GCK70_RS12945	COG1944	ATP diphosphatase activity
GCK70_RS12950	COG2116	formate transmembrane transporter activity
GCK70_RS12955	COG1882	Formate acetyltransferase
GCK70_RS12965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GCK70_RS12980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GCK70_RS12990	COG1674	ftsk spoiiie
GCK70_RS12990	COG3107	peptidoglycan biosynthetic process
GCK70_RS13000	COG0492	ferredoxin-NADP+ reductase activity
GCK70_RS13010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GCK70_RS13020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GCK70_RS13035	COG0542	response to heat
GCK70_RS13050	COG1278	Cold shock
GCK70_RS13060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_RS13065	COG2990	Protein conserved in bacteria
GCK70_RS13070	COG3593	DNA synthesis involved in DNA repair
GCK70_RS13075	COG2431	L-lysine efflux transmembrane transporter activity
GCK70_RS13085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_RS13090	COG0028	Belongs to the TPP enzyme family
GCK70_RS13100	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GCK70_RS13105	COG0702	epimerase
GCK70_RS13110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GCK70_RS13120	COG1605	Chorismate mutase
GCK70_RS13125	COG1126	abc transporter atp-binding protein
GCK70_RS13130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_RS13135	COG4215	(ABC) transporter
GCK70_RS13140	COG4160	amino acid transport
GCK70_RS13160	COG1120	ATPase activity
GCK70_RS13165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_RS13170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_RS13195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_RS13210	COG1177	transmembrane transport
GCK70_RS13215	COG1176	ABC-type spermidine putrescine transport system, permease component I
GCK70_RS13220	COG3842	ATPase activity
GCK70_RS13225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GCK70_RS13260	COG0671	phosphoesterase, PA-phosphatase related
GCK70_RS13270	COG1349	DNA-binding transcription factor activity
GCK70_RS13275	COG0814	amino acid
GCK70_RS13280	COG1686	Belongs to the peptidase S11 family
GCK70_RS13285	COG2011	ABC-type metal ion transport system permease component
GCK70_RS13310	COG0625	glutathione transferase activity
GCK70_RS13320	COG4771	TonB-dependent receptor
GCK70_RS13330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GCK70_RS13340	COG0833	amino acid
GCK70_RS13345	COG0583	DNA-binding transcription factor activity
GCK70_RS13350	COG2855	membrane
GCK70_RS13360	COG3188	usher protein
GCK70_RS13365	COG3121	Chaperone
GCK70_RS13380	COG3710	Transcriptional regulator
GCK70_RS13385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_RS13385	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GCK70_RS13385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_RS13390	COG1105	Belongs to the carbohydrate kinase PfkB family
GCK70_RS13400	COG0494	nUDIX hydrolase
GCK70_RS13410	COG1129	ABC transporter
GCK70_RS13445	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS13470	COG0246	Mannitol dehydrogenase
GCK70_RS13475	COG2186	Transcriptional regulator
GCK70_RS13485	COG0523	cobalamin synthesis protein
GCK70_RS13490	COG0671	phosphoesterase, PA-phosphatase related
GCK70_RS13495	COG0791	NLP P60 protein
GCK70_RS13500	COG2200	EAL domain
GCK70_RS13505	COG4166	transmembrane transport
GCK70_RS13510	COG4174	ABC transporter (Permease)
GCK70_RS13515	COG4239	(ABC) transporter, permease
GCK70_RS13520	COG4172	Belongs to the ABC transporter superfamily
GCK70_RS13530	COG2814	Major facilitator Superfamily
GCK70_RS13535	COG1187	pseudouridine synthase activity
GCK70_RS13540	COG1061	Type III restriction enzyme res subunit
GCK70_RS13565	COG3082	Protein of unknown function (DUF1414)
GCK70_RS13570	COG3083	sulfuric ester hydrolase activity
GCK70_RS13590	COG3157	Type VI secretion system effector, Hcp
GCK70_RS13605	COG2723	6-phospho-beta-galactosidase activity
GCK70_RS13610	COG1737	Transcriptional regulator
GCK70_RS13630	COG3299	homolog of phage Mu protein gp47
GCK70_RS13670	COG4386	tail sheath protein
GCK70_RS13690	COG3622	Belongs to the hyi family
GCK70_RS13695	COG1349	DNA-binding transcription factor activity
GCK70_RS13700	COG0235	Class ii aldolase
GCK70_RS13705	COG3395	kinase activity
GCK70_RS13750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GCK70_RS13780	COG2223	nitrite transmembrane transporter activity
GCK70_RS13785	COG0642	Histidine kinase
GCK70_RS13785	COG2198	Histidine kinase
GCK70_RS13790	COG0642	Histidine kinase
GCK70_RS13790	COG2198	Histidine kinase
GCK70_RS13800	COG2205	protein histidine kinase activity
GCK70_RS13800	COG0784	Response regulator, receiver
GCK70_RS13825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GCK70_RS13840	COG0814	amino acid
GCK70_RS13870	COG0697	spore germination
GCK70_RS13880	COG1982	Orn Lys Arg decarboxylase major
GCK70_RS13885	COG0531	amino acid
GCK70_RS13890	COG1174	glycine betaine transport
GCK70_RS13895	COG1125	glycine betaine transport
GCK70_RS13900	COG1174	glycine betaine transport
GCK70_RS13910	COG2897	thiosulfate sulfurtransferase activity
GCK70_RS13930	COG1122	ATPase activity
GCK70_RS13950	COG4807	Protein conserved in bacteria
GCK70_RS13965	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GCK70_RS13975	COG2261	transglycosylase associated protein
GCK70_RS13995	COG0277	FAD linked oxidase domain protein
GCK70_RS14000	COG1686	Belongs to the peptidase S11 family
GCK70_RS14010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK70_RS14035	COG3328	transposase activity
GCK70_RS14070	COG0513	Belongs to the DEAD box helicase family
GCK70_RS14075	COG1309	transcriptional regulator
GCK70_RS14085	COG1131	(ABC) transporter
GCK70_RS14090	COG0842	Transport permease protein
GCK70_RS14095	COG0842	Transport permease protein
GCK70_RS14115	COG1902	pentaerythritol trinitrate reductase activity
GCK70_RS14150	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GCK70_RS14160	COG0583	DNA-binding transcription factor activity
GCK70_RS14165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GCK70_RS14190	COG0670	Belongs to the BI1 family
GCK70_RS14195	COG0314	molybdopterin synthase activity
GCK70_RS14200	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GCK70_RS14210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GCK70_RS14215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GCK70_RS14220	COG4628	conserved protein (DUF2132)
GCK70_RS14230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GCK70_RS14240	COG2226	methyltransferase
GCK70_RS14265	COG0561	phosphatase activity
GCK70_RS14275	COG4149	molybdate abc transporter
GCK70_RS14280	COG0725	ABC transporter, periplasmic molybdate-binding protein
GCK70_RS14290	COG3585	molybdate ion transport
GCK70_RS14290	COG2005	Transcriptional regulator
GCK70_RS14300	COG1119	ATPase activity
GCK70_RS14310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GCK70_RS14315	COG1085	galactose-1-phosphate uridylyltransferase
GCK70_RS14330	COG2017	converts alpha-aldose to the beta-anomer
GCK70_RS14345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GCK70_RS14350	COG1230	cation diffusion facilitator family transporter
GCK70_RS14380	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GCK70_RS14385	COG2885	chlorophyll binding
GCK70_RS14395	COG3064	Membrane
GCK70_RS14395	COG3064	Membrane
GCK70_RS14400	COG0848	biopolymer transport protein
GCK70_RS14405	COG0811	peptide transport
GCK70_RS14410	COG0824	Thioesterase
GCK70_RS14415	COG3790	cyd operon protein YbgE
GCK70_RS14420	COG4890	Cyd operon protein YbgT
GCK70_RS14425	COG1294	oxidase, subunit
GCK70_RS14430	COG1271	oxidase subunit
GCK70_RS14435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GCK70_RS14445	COG0508	dehydrogenase complex catalyzes the overall conversion of
GCK70_RS14450	COG0567	Dehydrogenase, E1 component
GCK70_RS14460	COG1053	succinate dehydrogenase
GCK70_RS14465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GCK70_RS14470	COG2009	succinate dehydrogenase
GCK70_RS14485	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GCK70_RS14490	COG0497	DNA recombination
GCK70_RS14495	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GCK70_RS14505	COG2867	negative regulation of translational initiation
GCK70_RS14530	COG0582	viral genome integration into host DNA
GCK70_RS14590	COG3657	addiction module killer protein
GCK70_RS14615	COG1953	Uracil, thiamine, allantoin
GCK70_RS14635	COG2226	methyltransferase
GCK70_RS14640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK70_RS14645	COG0741	lytic transglycosylase activity
GCK70_RS14645	COG1388	LysM domain
GCK70_RS14660	COG0656	L-ascorbic acid biosynthetic process
GCK70_RS14695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GCK70_RS14705	COG2011	ABC-type metal ion transport system permease component
GCK70_RS14710	COG1464	Belongs to the NlpA lipoprotein family
GCK70_RS14720	COG1720	tRNA m6t6A37 methyltransferase activity
GCK70_RS14730	COG3015	lipoprotein NlpE involved in copper resistance
GCK70_RS14740	COG4681	YaeQ
GCK70_RS14750	COG4568	rho-dependent transcription termination
GCK70_RS14760	COG0037	tRNA processing
GCK70_RS14765	COG0346	lactoylglutathione lyase activity
GCK70_RS14775	COG0587	DNA-directed DNA polymerase activity
GCK70_RS14800	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GCK70_RS14815	COG0750	zinc metalloprotease
GCK70_RS14820	COG0575	Belongs to the CDS family
GCK70_RS14885	COG0564	pseudouridine synthase activity
GCK70_RS14890	COG3098	single-species biofilm formation
GCK70_RS14910	COG1611	Belongs to the LOG family
GCK70_RS14930	COG2363	Small membrane protein
GCK70_RS14935	COG0583	DNA-binding transcription factor activity
GCK70_RS14945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GCK70_RS14950	COG2166	iron-sulfur cluster assembly
GCK70_RS14955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GCK70_RS14960	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GCK70_RS14975	COG0860	N-Acetylmuramoyl-L-alanine amidase
GCK70_RS14985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GCK70_RS14990	COG1074	ATP-dependent DNA helicase activity
GCK70_RS15000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GCK70_RS15070	COG0667	Aldo Keto reductase
GCK70_RS15100	COG1609	Transcriptional regulator
GCK70_RS15110	COG0583	DNA-binding transcription factor activity
GCK70_RS15115	COG2814	Major facilitator Superfamily
GCK70_RS15120	COG0583	DNA-binding transcription factor activity
GCK70_RS15135	COG0840	transmembrane signaling receptor activity
GCK70_RS15180	COG2165	general secretion pathway protein
GCK70_RS15205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GCK70_RS15230	COG0288	reversible hydration of carbon dioxide
GCK70_RS15275	COG3119	arylsulfatase activity
GCK70_RS15280	COG1349	DNA-binding transcription factor activity
GCK70_RS15290	COG2222	sugar isomerase
GCK70_RS15295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_RS15300	COG3715	PTS system
GCK70_RS15305	COG3716	PTS system mannose fructose sorbose family IID component
GCK70_RS15310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
GCK70_RS15330	COG0641	radical SAM
GCK70_RS15335	COG3119	arylsulfatase activity
GCK70_RS15365	COG2271	Major facilitator Superfamily
GCK70_RS15385	COG1263	PTS System
GCK70_RS15385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_RS15390	COG1874	Beta-galactosidase
GCK70_RS15395	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GCK70_RS15400	COG3833	ABC-type maltose transport systems, permease component
GCK70_RS15405	COG1175	transmembrane transport
GCK70_RS15410	COG2182	Extracellular solute-binding protein
GCK70_RS15420	COG1129	ABC transporter
GCK70_RS15425	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS15430	COG1879	ABC-type sugar transport system periplasmic component
GCK70_RS15440	COG0791	NLP P60 protein
GCK70_RS15445	COG1695	Transcriptional regulator
GCK70_RS15535	COG2944	sequence-specific DNA binding
GCK70_RS15560	COG0582	viral genome integration into host DNA
GCK70_RS15580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GCK70_RS15585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK70_RS15590	COG4974	Belongs to the 'phage' integrase family
GCK70_RS15595	COG0716	FMN binding
GCK70_RS15600	COG4452	Inner membrane protein CreD
GCK70_RS15605	COG2205	protein histidine kinase activity
GCK70_RS15610	COG0745	RESPONSE REGULATOR receiver
GCK70_RS15635	COG1272	protein, Hemolysin III
GCK70_RS15680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK70_RS15685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GCK70_RS15690	COG0006	proline dipeptidase activity
GCK70_RS15710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GCK70_RS15715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GCK70_RS15750	COG0191	fructose-bisphosphate aldolase activity
GCK70_RS15785	COG2259	Doxx family
GCK70_RS15795	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
GCK70_RS15800	COG4575	ribosome binding
GCK70_RS15820	COG0586	Pfam SNARE associated Golgi protein
GCK70_RS15835	COG2271	Major facilitator Superfamily
GCK70_RS15850	COG2721	sulfolactate sulfo-lyase activity
GCK70_RS15870	COG0673	inositol 2-dehydrogenase activity
GCK70_RS15875	COG1451	nucleotide metabolic process
GCK70_RS15890	COG1902	pentaerythritol trinitrate reductase activity
GCK70_RS15890	COG0446	pyridine nucleotide-disulphide oxidoreductase
GCK70_RS15895	COG3247	response to pH
GCK70_RS15915	COG4245	von Willebrand factor, type A
GCK70_RS15930	COG4245	von Willebrand factor, type A
GCK70_RS15935	COG2831	hemolysin activation secretion protein
GCK70_RS15940	COG3210	domain, Protein
GCK70_RS15965	COG3210	domain, Protein
GCK70_RS15970	COG3210	domain, Protein
GCK70_RS15990	COG3842	ATPase activity
GCK70_RS15995	COG3459	Glycosyltransferase 36 associated
GCK70_RS16000	COG1609	Transcriptional regulator
GCK70_RS16005	COG2182	Extracellular solute-binding protein
GCK70_RS16015	COG0395	ABC-type sugar transport system, permease component
GCK70_RS16035	COG1289	transmembrane transporter activity
GCK70_RS16060	COG0436	Aminotransferase
GCK70_RS16080	COG0251	oxidation-reduction process
GCK70_RS16155	COG0358	DNA primase activity
GCK70_RS16160	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GCK70_RS16180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GCK70_RS16195	COG4991	sh3 domain protein
GCK70_RS16200	COG3025	triphosphatase activity
GCK70_RS16215	COG0531	amino acid
GCK70_RS16235	COG3384	dioxygenase
GCK70_RS16240	COG0754	glutathionylspermidine amidase activity
GCK70_RS16255	COG1538	Outer membrane efflux protein
GCK70_RS16260	COG0494	nUDIX hydrolase
GCK70_RS16265	COG3151	Protein conserved in bacteria
GCK70_RS16270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GCK70_RS16275	COG3150	esterase
GCK70_RS16285	COG0583	DNA-binding transcription factor activity
GCK70_RS16290	COG2249	NAD(P)H dehydrogenase (quinone) activity
GCK70_RS16300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GCK70_RS16315	COG2132	Multicopper oxidase
GCK70_RS16330	COG0656	L-ascorbic acid biosynthetic process
GCK70_RS16340	COG1979	alcohol dehydrogenase
GCK70_RS16345	COG2207	Transcriptional regulator
GCK70_RS16350	COG0586	Pfam SNARE associated Golgi protein
GCK70_RS16355	COG0626	cystathionine gamma-synthase activity
GCK70_RS16360	COG0811	peptide transport
GCK70_RS16365	COG0848	biopolymer transport protein
GCK70_RS16420	COG4964	Belongs to the GSP D family
GCK70_RS16425	COG4964	Belongs to the GSP D family
GCK70_RS16460	COG4592	Periplasmic binding protein
GCK70_RS16480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GCK70_RS16485	COG1684	flagellar biosynthetic protein fliR
GCK70_RS16490	COG1987	bacterial-type flagellum assembly
GCK70_RS16515	COG1677	Flagellar hook-basal body complex protein FliE
GCK70_RS16555	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GCK70_RS16560	COG1815	bacterial-type flagellum-dependent cell motility
GCK70_RS16565	COG1558	bacterial-type flagellum-dependent cell motility
GCK70_RS16570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GCK70_RS16575	COG1749	Flagellar hook protein flgE
GCK70_RS16580	COG4787	bacterial-type flagellum-dependent cell motility
GCK70_RS16585	COG4786	Flagellar basal body rod
GCK70_RS16595	COG1706	bacterial-type flagellum-dependent cell motility
GCK70_RS16605	COG1256	bacterial-type flagellum assembly
GCK70_RS16625	COG3710	Transcriptional regulator
GCK70_RS16645	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GCK70_RS16670	COG1191	sigma factor activity
GCK70_RS16675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GCK70_RS16745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_RS16800	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GCK70_RS16805	COG2195	Cleaves the N-terminal amino acid of tripeptides
GCK70_RS16810	COG4771	TonB-dependent receptor
GCK70_RS16830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GCK70_RS16830	COG2226	methyltransferase
GCK70_RS16830	COG3433	isochorismatase activity
GCK70_RS16865	COG2375	cellular response to nickel ion
GCK70_RS16865	COG1132	(ABC) transporter
GCK70_RS16870	COG1132	(ABC) transporter
GCK70_RS16885	COG2610	gluconate transmembrane transporter activity
GCK70_RS16895	COG3501	Rhs element vgr protein
GCK70_RS16905	COG3209	COG3209 Rhs family protein
GCK70_RS16925	COG0471	metal ion transport
GCK70_RS16945	COG2211	Major facilitator Superfamily
GCK70_RS16995	COG2771	luxR family
GCK70_RS17000	COG3916	Acyl-homoserine-lactone synthase
GCK70_RS17130	COG1982	Orn Lys Arg decarboxylase major
GCK70_RS17135	COG1879	ABC-type sugar transport system periplasmic component
GCK70_RS17140	COG1129	ABC transporter
GCK70_RS17145	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS17150	COG4774	siderophore transport
GCK70_RS17170	COG1194	a g-specific adenine glycosylase
GCK70_RS17180	COG3171	Protein conserved in bacteria
GCK70_RS17195	COG1073	alpha beta
GCK70_RS17195	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GCK70_RS17195	COG3064	Membrane
GCK70_RS17200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK70_RS17205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GCK70_RS17215	COG0762	integral membrane protein
GCK70_RS17225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GCK70_RS17230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GCK70_RS17235	COG2805	Type II/IV secretion system protein
GCK70_RS17245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK70_RS17260	COG0189	ligase activity
GCK70_RS17265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GCK70_RS17270	COG2356	endonuclease I
GCK70_RS17285	COG1166	arginine decarboxylase activity
GCK70_RS17300	COG0501	Belongs to the peptidase M48B family
GCK70_RS17305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GCK70_RS17325	COG0494	nUDIX hydrolase
GCK70_RS17355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GCK70_RS17360	COG0849	cell division
GCK70_RS17365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GCK70_RS17385	COG0772	Belongs to the SEDS family
GCK70_RS17400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GCK70_RS17405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GCK70_RS17410	COG0768	penicillin binding
GCK70_RS17415	COG3116	cell division
GCK70_RS17440	COG1609	Transcriptional regulator
GCK70_RS17460	COG0028	Belongs to the TPP enzyme family
GCK70_RS17470	COG1022	Amp-dependent synthetase and ligase
GCK70_RS17500	COG0473	3-isopropylmalate dehydrogenase activity
GCK70_RS17515	COG2814	Major facilitator Superfamily
GCK70_RS17530	COG4143	(ABC) transporter
GCK70_RS17535	COG1178	ABC-type Fe3 transport system permease component
GCK70_RS17540	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GCK70_RS17545	COG0586	Pfam SNARE associated Golgi protein
GCK70_RS17550	COG0417	DNA replication proofreading
GCK70_RS17570	COG3047	cAMP biosynthetic process
GCK70_RS17570	COG2885	chlorophyll binding
GCK70_RS17655	COG0564	pseudouridine synthase activity
GCK70_RS17660	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GCK70_RS17710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GCK70_RS17720	COG2966	Psort location CytoplasmicMembrane, score
GCK70_RS17725	COG1280	lysine exporter protein (LysE YggA)
GCK70_RS17730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GCK70_RS17755	COG1047	Peptidyl-prolyl cis-trans
GCK70_RS17770	COG0196	riboflavin kinase activity
GCK70_RS17790	COG0583	DNA-binding transcription factor activity
GCK70_RS17810	COG1584	GPR1 FUN34 yaaH family protein
GCK70_RS17825	COG0521	Mo-molybdopterin cofactor biosynthetic process
GCK70_RS17865	COG0745	RESPONSE REGULATOR receiver
GCK70_RS17870	COG3045	CreA protein
GCK70_RS17880	COG3708	Transcriptional regulator
GCK70_RS17880	COG2207	Transcriptional regulator
GCK70_RS17895	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GCK70_RS17900	COG0741	lytic transglycosylase activity
GCK70_RS17915	COG2199	diguanylate cyclase activity
GCK70_RS17920	COG2885	chlorophyll binding
GCK70_RS17945	COG0560	Phosphoserine phosphatase
GCK70_RS17950	COG3726	membrane protein affecting hemolysin expression
GCK70_RS17975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GCK70_RS17980	COG0084	hydrolase, TatD family'
GCK70_RS17985	COG4667	esterase of the alpha-beta hydrolase superfamily
GCK70_RS17995	COG2823	Periplasmic or secreted lipoprotein
GCK70_RS18005	COG0456	acetyltransferase
GCK70_RS18010	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GCK70_RS18055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GCK70_RS18060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GCK70_RS18075	COG0859	PFAM glycosyl transferase family 9
GCK70_RS18080	COG1070	Carbohydrate kinase
GCK70_RS18130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_RS18130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GCK70_RS18130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_RS18135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_RS18140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_RS18145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GCK70_RS18150	COG2207	Transcriptional regulator
GCK70_RS18160	COG4269	membrane
GCK70_RS18220	COG1401	restriction endodeoxyribonuclease activity
GCK70_RS18240	COG0583	DNA-binding transcription factor activity
GCK70_RS18245	COG1741	Belongs to the pirin family
GCK70_RS18255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GCK70_RS18275	COG2823	Periplasmic or secreted lipoprotein
GCK70_RS18285	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GCK70_RS18295	COG2198	Histidine kinase
GCK70_RS18295	COG0784	Response regulator, receiver
GCK70_RS18295	COG5002	protein histidine kinase activity
GCK70_RS18305	COG1242	4 iron, 4 sulfur cluster binding
GCK70_RS18310	COG0069	glutamate synthase activity
GCK70_RS18310	COG0067	glutamate synthase
GCK70_RS18310	COG0070	glutamate synthase
GCK70_RS18315	COG0493	'glutamate synthase
GCK70_RS18325	COG2969	positive regulation of protein catabolic process
GCK70_RS18330	COG0625	glutathione transferase activity
GCK70_RS18350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GCK70_RS18355	COG3105	Protein conserved in bacteria
GCK70_RS18360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK70_RS18370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GCK70_RS18380	COG5007	Belongs to the BolA IbaG family
GCK70_RS18385	COG3113	response to antibiotic
GCK70_RS18390	COG2854	intermembrane phospholipid transfer
GCK70_RS18395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GCK70_RS18400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GCK70_RS18405	COG1127	ABC transporter
GCK70_RS18410	COG0530	calcium, potassium:sodium antiporter activity
GCK70_RS18415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GCK70_RS18415	COG0517	IMP dehydrogenase activity
GCK70_RS18420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GCK70_RS18425	COG3117	lipopolysaccharide transmembrane transporter activity
GCK70_RS18430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GCK70_RS18435	COG1137	ATPase activity
GCK70_RS18440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GCK70_RS18465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GCK70_RS18495	COG1609	Transcriptional regulator
GCK70_RS18500	COG1263	PTS System
GCK70_RS18500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GCK70_RS18505	COG0366	Alpha amylase catalytic
GCK70_RS18510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK70_RS18515	COG3783	Cytochrome b(562)
GCK70_RS18525	COG0312	modulator of DNA gyrase
GCK70_RS18535	COG2732	(Barnase) inhibitor
GCK70_RS18565	COG0583	DNA-binding transcription factor activity
GCK70_RS18615	COG0312	modulator of DNA gyrase
GCK70_RS18620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GCK70_RS18625	COG3164	Protein of unknown function
GCK70_RS18630	COG1530	ribonuclease E activity
GCK70_RS18635	COG0424	maF-like protein
GCK70_RS18640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GCK70_RS18645	COG1792	Involved in formation and maintenance of cell shape
GCK70_RS18650	COG1077	Cell shape determining protein MreB Mrl
GCK70_RS18655	COG2200	EAL domain
GCK70_RS18655	COG2199	diguanylate cyclase activity
GCK70_RS18660	COG0604	alcohol dehydrogenase
GCK70_RS18665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GCK70_RS18680	COG0511	ligase activity, forming carbon-carbon bonds
GCK70_RS18685	COG0439	Biotin carboxylase
GCK70_RS18690	COG3924	membrane
GCK70_RS18695	COG4145	pantothenate transmembrane transporter activity
GCK70_RS18705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GCK70_RS18710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GCK70_RS18740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GCK70_RS18750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GCK70_RS18755	COG3133	Outer membrane lipoprotein
GCK70_RS18765	COG1278	Cold shock
GCK70_RS18770	COG1278	Cold shock
GCK70_RS18790	COG0625	glutathione transferase activity
GCK70_RS18800	COG1069	ribulokinase activity
GCK70_RS18810	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS18815	COG1129	ABC transporter
GCK70_RS18825	COG1560	Kdo2-lipid A biosynthetic process
GCK70_RS18835	COG0025	NhaP-type Na H and K H
GCK70_RS18840	COG2252	PERMEase
GCK70_RS18845	COG3077	Addiction module antitoxin, RelB DinJ family
GCK70_RS18860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK70_RS18870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK70_RS18875	COG0431	NADPH-dependent FMN reductase
GCK70_RS18880	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GCK70_RS18885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_RS18890	COG1869	D-ribose catabolic process
GCK70_RS18895	COG1917	Cupin 2, conserved barrel domain protein
GCK70_RS18895	COG2207	Transcriptional regulator
GCK70_RS18900	COG0673	inositol 2-dehydrogenase activity
GCK70_RS18920	COG3209	COG3209 Rhs family protein
GCK70_RS18935	COG3501	Rhs element vgr protein
GCK70_RS19080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GCK70_RS19085	COG0058	SHG alpha-glucan phosphorylase activity
GCK70_RS19110	COG3275	phosphorelay sensor kinase activity
GCK70_RS19140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GCK70_RS19145	COG2095	MarC family integral membrane protein
GCK70_RS19165	COG3265	gluconokinase activity
GCK70_RS19170	COG2610	gluconate transmembrane transporter activity
GCK70_RS19175	COG1609	Transcriptional regulator
GCK70_RS19180	COG1741	Belongs to the pirin family
GCK70_RS19205	COG0191	fructose-bisphosphate aldolase activity
GCK70_RS19220	COG1172	Belongs to the binding-protein-dependent transport system permease family
GCK70_RS19235	COG2081	HI0933 family
GCK70_RS19240	COG0306	phosphate transporter
GCK70_RS19255	COG0589	response to stress
GCK70_RS19275	COG0339	signal peptide processing
GCK70_RS19280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GCK70_RS19285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GCK70_RS19290	COG3835	regulator
GCK70_RS19300	COG2610	gluconate transmembrane transporter activity
GCK70_RS19305	COG1929	Belongs to the glycerate kinase type-1 family
GCK70_RS19330	COG1295	ribonuclease BN
GCK70_RS19335	COG2134	cdp-diacylglycerol pyrophosphatase
GCK70_RS19340	COG2982	Protein involved in outer membrane biogenesis
GCK70_RS19345	COG2200	EAL domain
GCK70_RS19350	COG1942	4-Oxalocrotonate Tautomerase
GCK70_RS19355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_RS19360	COG0612	Peptidase, M16
GCK70_RS19380	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GCK70_RS19385	COG2200	EAL domain
GCK70_RS19385	COG2199	diguanylate cyclase activity
GCK70_RS19390	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK70_RS19395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GCK70_RS19400	COG4608	Belongs to the ABC transporter superfamily
GCK70_RS19405	COG0444	Belongs to the ABC transporter superfamily
GCK70_RS19410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GCK70_RS19415	COG0601	transmembrane transport
GCK70_RS19420	COG0747	negative chemotaxis
GCK70_RS19430	COG2831	hemolysin activation secretion protein
GCK70_RS19445	COG2271	Major facilitator Superfamily
GCK70_RS19470	COG2197	response regulator
GCK70_RS19475	COG2194	sulfuric ester hydrolase activity
GCK70_RS19490	COG2986	histidine ammonia-lyase
GCK70_RS19520	COG4607	ABC-type enterochelin transport system periplasmic component
GCK70_RS19530	COG4605	iron ion homeostasis
GCK70_RS19535	COG4604	ABC transporter, ATP-binding protein
GCK70_RS19585	COG0582	viral genome integration into host DNA
GCK70_RS19595	COG1609	Transcriptional regulator
GCK70_RS19595	COG2207	Transcriptional regulator
GCK70_RS19600	COG4214	carbohydrate transport
GCK70_RS19610	COG4213	ABC transporter substrate-binding protein
GCK70_RS19620	COG1070	Carbohydrate kinase
GCK70_RS19630	COG3121	Chaperone
GCK70_RS19645	COG3274	enterobacterial common antigen metabolic process
GCK70_RS19715	COG1175	transmembrane transport
GCK70_RS19720	COG3833	ABC-type maltose transport systems, permease component
GCK70_RS19735	COG0527	aspartate kinase activity
GCK70_RS19765	COG2224	Isocitrate lyase
GCK70_RS19770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GCK70_RS19830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GCK70_RS19845	COG0551	DNA topoisomerase type I activity
GCK70_RS19855	COG0758	DNA mediated transformation
GCK70_RS19885	COG3036	rescue of stalled ribosome
GCK70_RS19890	COG0789	Transcriptional regulator
GCK70_RS19905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GCK70_RS19920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GCK70_RS19925	COG0201	protein transport
GCK70_RS19935	COG1841	ribosomal large subunit assembly
GCK70_RS19975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GCK70_RS19980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GCK70_RS19990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GCK70_RS19995	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GCK70_RS20005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GCK70_RS20015	COG0089	rRNA binding
GCK70_RS20030	COG0051	transcription antitermination factor activity, RNA binding
GCK70_RS20065	COG0049	tRNA binding
GCK70_RS20070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GCK70_RS20090	COG2964	Protein conserved in bacteria
GCK70_RS20095	COG0545	Peptidyl-prolyl cis-trans isomerase
GCK70_RS20110	COG1047	Peptidyl-prolyl cis-trans
GCK70_RS20115	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GCK70_RS20135	COG1216	Glycosyl transferase, family 2
GCK70_RS20145	COG2175	clavaminate synthase activity
GCK70_RS20150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GCK70_RS20160	COG4521	taurine ABC transporter
GCK70_RS20170	COG0429	hydrolase of the alpha beta-hydrolase fold
GCK70_RS20180	COG3954	Phosphoribulokinase
GCK70_RS20190	COG1765	OsmC-like protein
GCK70_RS20200	COG1289	transmembrane transporter activity
GCK70_RS20215	COG0433	COG0433 Predicted ATPase
GCK70_RS20220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GCK70_RS20225	COG1486	melibiose metabolic process
GCK70_RS20245	COG0402	S-adenosylhomocysteine deaminase activity
GCK70_RS20250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GCK70_RS20270	COG0180	Tryptophanyl-tRNA synthetase
GCK70_RS20275	COG0546	phosphoglycolate phosphatase activity
GCK70_RS20280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GCK70_RS20305	COG4796	Type ii and iii secretion system protein
GCK70_RS20335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GCK70_RS20340	COG0494	nUDIX hydrolase
GCK70_RS20350	COG1011	Hydrolase
GCK70_RS20355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GCK70_RS20380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GCK70_RS20385	COG2183	response to ionizing radiation
GCK70_RS20390	COG1918	ferrous iron import across plasma membrane
GCK70_RS20425	COG1640	4-alpha-glucanotransferase
GCK70_RS20430	COG0058	SHG alpha-glucan phosphorylase activity
GCK70_RS20435	COG0058	SHG alpha-glucan phosphorylase activity
GCK70_RS20455	COG1349	DNA-binding transcription factor activity
GCK70_RS20475	COG0460	homoserine dehydrogenase
GCK70_RS20475	COG0527	aspartate kinase activity
GCK70_RS20490	COG4682	membrane
GCK70_RS20500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GCK70_RS20510	COG1609	Transcriptional regulator
GCK70_RS20515	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GCK70_RS20530	COG1575	Belongs to the MenA family. Type 1 subfamily
GCK70_RS20590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GCK70_RS20595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GCK70_RS20600	COG1494	fructose-1,6-bisphosphatase
GCK70_RS20610	COG3152	Membrane
GCK70_RS20625	COG0583	DNA-binding transcription factor activity
GCK70_RS20630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GCK70_RS20635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GCK70_RS20640	COG0471	metal ion transport
GCK70_RS20650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GCK70_RS20680	COG3678	ATP-independent chaperone mediated protein folding
GCK70_RS20685	COG0745	RESPONSE REGULATOR receiver
GCK70_RS20690	COG2205	protein histidine kinase activity
GCK70_RS20695	COG2169	Transcriptional regulator
GCK70_RS20695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GCK70_RS20700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GCK70_RS20705	COG1045	serine acetyltransferase
GCK70_RS20725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GCK70_RS20730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GCK70_RS20740	COG4942	peptidase
GCK70_RS20755	COG0156	8-amino-7-oxononanoate synthase activity
GCK70_RS20765	COG0859	PFAM glycosyl transferase family 9
GCK70_RS20770	COG0859	PFAM glycosyl transferase family 9
GCK70_RS20775	COG1519	Transferase
GCK70_RS20815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GCK70_RS20840	COG1561	YicC-like family, N-terminal region
GCK70_RS20845	COG2860	membrane
GCK70_RS20865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GCK70_RS20870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GCK70_RS20875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK70_RS20885	COG0786	glutamate:sodium symporter activity
GCK70_RS20890	COG2233	PERMEase
GCK70_RS20895	COG2982	Protein involved in outer membrane biogenesis
GCK70_RS20900	COG0456	acetyltransferase
GCK70_RS20925	COG1011	Hydrolase
GCK70_RS20935	COG0174	glutamine synthetase
GCK70_RS20940	COG3852	Histidine kinase
GCK70_RS20950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GCK70_RS20980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK70_RS20980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK70_RS20985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GCK70_RS20990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GCK70_RS20995	COG3084	Protein conserved in bacteria
GCK70_RS21005	COG1763	Mo-molybdopterin cofactor biosynthetic process
GCK70_RS21010	COG3328	transposase activity
GCK70_RS21040	COG2186	Transcriptional regulator
GCK70_RS21045	COG0477	Major facilitator Superfamily
GCK70_RS21060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GCK70_RS21090	COG1522	sequence-specific DNA binding
GCK70_RS21095	COG0716	FMN binding
GCK70_RS21115	COG3312	ion transport
GCK70_RS21175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GCK70_RS21180	COG0573	inorganic phosphate transmembrane transporter activity
GCK70_RS21185	COG0581	inorganic phosphate transmembrane transporter activity
GCK70_RS21195	COG0704	Plays a role in the regulation of phosphate uptake
GCK70_RS21205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GCK70_RS21210	COG0765	amino acid transport
GCK70_RS21215	COG0765	amino acid transport
GCK70_RS21220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GCK70_RS21230	COG2252	PERMEase
GCK70_RS21260	COG0706	membrane insertase activity
GCK70_RS21275	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GCK70_RS21340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GCK70_RS21350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GCK70_RS21470	COG1475	DNA binding
GCK70_RS21570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GCK70_RS21580	COG3344	reverse transcriptase
GCK70_RS21605	COG3328	transposase activity
GCK70_RS21645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GCK70_RS21690	COG3941	tape measure
GCK70_RS21785	COG1475	DNA binding
GCK70_RS21790	COG1475	DNA binding
GCK70_RS21795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GCK70_RS21885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GCK70_RS21935	COG0515	serine threonine protein kinase
GCK70_RS21975	COG5599	Phosphatase
GCK70_RS21980	COG1317	bacterial-type flagellum organization
GCK70_RS21990	COG4669	(LipO)protein
GCK70_RS22025	COG1450	Type ii and iii secretion system protein
GCK70_RS22040	COG2207	Transcriptional regulator
GCK70_RS22050	COG4792	protein secretion
GCK70_RS22055	COG4791	protein targeting
GCK70_RS22060	COG4794	Type iii secretion
GCK70_RS22065	COG4790	Type iii secretion
GCK70_RS22115	COG4789	Type iii secretion
GCK70_RS22135	COG0457	Tetratricopeptide repeat
GCK70_RS22160	COG4886	Leucine-rich repeat (LRR) protein
GCK70_RS22170	COG3328	transposase activity
GCK70_RS22195	COG3177	Filamentation induced by cAMP protein fic
GCK70_RS22250	COG3609	addiction module antidote protein, CC2985 family
GCK70_RS22470	COG5301	cellulose 1,4-beta-cellobiosidase activity
GCK70_RS22480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GCK70_RS22530	COG2161	toxin-antitoxin pair type II binding
GCK70_RS22535	COG4115	mRNA cleavage
GCK70_RS22600	COG3567	Phage-associated protein, HI1409 family
GCK70_RS22645	COG4683	PFAM Phage derived protein Gp49-like (DUF891)