locus-tag	class	description
YPZ3_RS00005	COG0716	FMN binding
YPZ3_RS00010	COG1522	sequence-specific DNA binding
YPZ3_RS00040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_RS00050	COG0477	Major facilitator Superfamily
YPZ3_RS00055	COG2186	Transcriptional regulator
YPZ3_RS00085	COG3328	transposase activity
YPZ3_RS00090	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPZ3_RS00100	COG3084	Protein conserved in bacteria
YPZ3_RS00105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPZ3_RS00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPZ3_RS00115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPZ3_RS00115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPZ3_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPZ3_RS00150	COG3852	Histidine kinase
YPZ3_RS00155	COG0174	glutamine synthetase
YPZ3_RS00170	COG1011	Hydrolase
YPZ3_RS00195	COG0456	acetyltransferase
YPZ3_RS00200	COG2982	Protein involved in outer membrane biogenesis
YPZ3_RS00205	COG2233	PERMEase
YPZ3_RS00210	COG0786	glutamate:sodium symporter activity
YPZ3_RS00215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPZ3_RS00220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPZ3_RS00225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPZ3_RS00245	COG2860	membrane
YPZ3_RS00250	COG1561	YicC-like family, N-terminal region
YPZ3_RS00275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPZ3_RS00310	COG1519	Transferase
YPZ3_RS00315	COG0859	PFAM glycosyl transferase family 9
YPZ3_RS00320	COG0859	PFAM glycosyl transferase family 9
YPZ3_RS00330	COG0156	8-amino-7-oxononanoate synthase activity
YPZ3_RS00345	COG4942	peptidase
YPZ3_RS00355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPZ3_RS00360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPZ3_RS00380	COG1045	serine acetyltransferase
YPZ3_RS00385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPZ3_RS00390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPZ3_RS00390	COG2169	Transcriptional regulator
YPZ3_RS00395	COG2205	protein histidine kinase activity
YPZ3_RS00400	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS00405	COG3678	ATP-independent chaperone mediated protein folding
YPZ3_RS00425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPZ3_RS00435	COG0471	metal ion transport
YPZ3_RS00440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPZ3_RS00445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPZ3_RS00450	COG0583	DNA-binding transcription factor activity
YPZ3_RS00465	COG3152	Membrane
YPZ3_RS00475	COG1494	fructose-1,6-bisphosphatase
YPZ3_RS00480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPZ3_RS00485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPZ3_RS00535	COG1575	Belongs to the MenA family. Type 1 subfamily
YPZ3_RS00550	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPZ3_RS00555	COG1609	Transcriptional regulator
YPZ3_RS00565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPZ3_RS00575	COG4682	membrane
YPZ3_RS00595	COG0527	aspartate kinase activity
YPZ3_RS00595	COG0460	homoserine dehydrogenase
YPZ3_RS00605	COG2801	Transposase and inactivated derivatives
YPZ3_RS00615	COG1349	DNA-binding transcription factor activity
YPZ3_RS00625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPZ3_RS00635	COG0058	SHG alpha-glucan phosphorylase activity
YPZ3_RS00640	COG0058	SHG alpha-glucan phosphorylase activity
YPZ3_RS00645	COG1640	4-alpha-glucanotransferase
YPZ3_RS00680	COG1918	ferrous iron import across plasma membrane
YPZ3_RS00690	COG2183	response to ionizing radiation
YPZ3_RS00695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPZ3_RS00720	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPZ3_RS00725	COG1011	Hydrolase
YPZ3_RS00740	COG0494	nUDIX hydrolase
YPZ3_RS00745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPZ3_RS00775	COG4796	Type ii and iii secretion system protein
YPZ3_RS00800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPZ3_RS00805	COG0546	phosphoglycolate phosphatase activity
YPZ3_RS00810	COG0180	Tryptophanyl-tRNA synthetase
YPZ3_RS00830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPZ3_RS00835	COG0402	S-adenosylhomocysteine deaminase activity
YPZ3_RS00855	COG1486	melibiose metabolic process
YPZ3_RS00860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPZ3_RS00865	COG0433	COG0433 Predicted ATPase
YPZ3_RS00880	COG1289	transmembrane transporter activity
YPZ3_RS00890	COG1765	OsmC-like protein
YPZ3_RS00900	COG3954	Phosphoribulokinase
YPZ3_RS00910	COG0429	hydrolase of the alpha beta-hydrolase fold
YPZ3_RS00920	COG4521	taurine ABC transporter
YPZ3_RS00930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPZ3_RS00935	COG2175	clavaminate synthase activity
YPZ3_RS00945	COG1216	Glycosyl transferase, family 2
YPZ3_RS00965	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPZ3_RS00970	COG1047	Peptidyl-prolyl cis-trans
YPZ3_RS00980	COG0545	Peptidyl-prolyl cis-trans isomerase
YPZ3_RS00985	COG2964	Protein conserved in bacteria
YPZ3_RS01005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPZ3_RS01010	COG0049	tRNA binding
YPZ3_RS01040	COG0051	transcription antitermination factor activity, RNA binding
YPZ3_RS01055	COG0089	rRNA binding
YPZ3_RS01065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPZ3_RS01075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPZ3_RS01080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPZ3_RS01090	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPZ3_RS01095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPZ3_RS01135	COG1841	ribosomal large subunit assembly
YPZ3_RS01145	COG0201	protein transport
YPZ3_RS01150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPZ3_RS01165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPZ3_RS01180	COG0789	Transcriptional regulator
YPZ3_RS01185	COG3036	rescue of stalled ribosome
YPZ3_RS01215	COG0758	DNA mediated transformation
YPZ3_RS01225	COG0551	DNA topoisomerase type I activity
YPZ3_RS01240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPZ3_RS01265	COG3162	membrane
YPZ3_RS01275	COG1301	dicarboxylic acid transport
YPZ3_RS01385	COG2391	methyltransferase activity
YPZ3_RS01390	COG0425	Belongs to the sulfur carrier protein TusA family
YPZ3_RS01395	COG0583	DNA-binding transcription factor activity
YPZ3_RS01400	COG0814	amino acid
YPZ3_RS01405	COG0626	cystathionine gamma-synthase activity
YPZ3_RS01415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_RS01420	COG4558	Periplasmic binding protein
YPZ3_RS01425	COG3720	iron ion transport
YPZ3_RS01430	COG4771	TonB-dependent receptor
YPZ3_RS01435	COG0702	epimerase
YPZ3_RS01440	COG3721	Heme iron utilization protein
YPZ3_RS01465	COG1358	cellular component organization or biogenesis
YPZ3_RS01525	COG3121	Chaperone
YPZ3_RS01570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPZ3_RS01580	COG0735	belongs to the Fur family
YPZ3_RS01585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPZ3_RS01610	COG1448	Aminotransferase
YPZ3_RS01615	COG2315	Protein conserved in bacteria
YPZ3_RS01620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPZ3_RS01625	COG0629	single-stranded DNA binding
YPZ3_RS01635	COG1454	alcohol dehydrogenase
YPZ3_RS01705	COG0305	Participates in initiation and elongation during chromosome replication
YPZ3_RS01745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPZ3_RS01970	COG3436	PFAM IS66 Orf2 family protein
YPZ3_RS01975	COG4372	Transposase
YPZ3_RS01990	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS02020	COG1309	transcriptional regulator
YPZ3_RS02025	COG0493	'glutamate synthase
YPZ3_RS02025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_RS02030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_RS02035	COG3383	formate dehydrogenase (NAD+) activity
YPZ3_RS02050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPZ3_RS02095	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPZ3_RS02105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPZ3_RS02110	COG1053	succinate dehydrogenase
YPZ3_RS02125	COG3264	Mechanosensitive ion channel
YPZ3_RS02125	COG1511	domain protein
YPZ3_RS02145	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YPZ3_RS02160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPZ3_RS02165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPZ3_RS02165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPZ3_RS02170	COG0802	atpase or kinase
YPZ3_RS02175	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPZ3_RS02195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPZ3_RS02200	COG0330	HflC and HflK could
YPZ3_RS02205	COG0330	HflC and HflK could
YPZ3_RS02210	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPZ3_RS02225	COG0557	exoribonuclease II activity
YPZ3_RS02230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPZ3_RS02235	COG1960	acyl-CoA dehydrogenase activity
YPZ3_RS02240	COG3650	response to hydrogen peroxide
YPZ3_RS02260	COG1401	restriction endodeoxyribonuclease activity
YPZ3_RS02275	COG2963	transposase activity
YPZ3_RS02330	COG4269	membrane
YPZ3_RS02340	COG2207	Transcriptional regulator
YPZ3_RS02345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_RS02350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_RS02355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_RS02360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_RS02360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_RS02360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPZ3_RS02410	COG1070	Carbohydrate kinase
YPZ3_RS02415	COG0859	PFAM glycosyl transferase family 9
YPZ3_RS02435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_RS02440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPZ3_RS02485	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPZ3_RS02490	COG0456	acetyltransferase
YPZ3_RS02500	COG2823	Periplasmic or secreted lipoprotein
YPZ3_RS02510	COG4667	esterase of the alpha-beta hydrolase superfamily
YPZ3_RS02515	COG0084	hydrolase, TatD family'
YPZ3_RS02520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPZ3_RS02550	COG3726	membrane protein affecting hemolysin expression
YPZ3_RS02555	COG0560	Phosphoserine phosphatase
YPZ3_RS02580	COG2885	chlorophyll binding
YPZ3_RS02585	COG2199	diguanylate cyclase activity
YPZ3_RS02600	COG0741	lytic transglycosylase activity
YPZ3_RS02605	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPZ3_RS02620	COG3708	Transcriptional regulator
YPZ3_RS02620	COG2207	Transcriptional regulator
YPZ3_RS02625	COG3045	CreA protein
YPZ3_RS02630	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS02660	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPZ3_RS02675	COG1584	GPR1 FUN34 yaaH family protein
YPZ3_RS02695	COG0583	DNA-binding transcription factor activity
YPZ3_RS02725	COG1047	Peptidyl-prolyl cis-trans
YPZ3_RS02760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPZ3_RS02765	COG1280	lysine exporter protein (LysE YggA)
YPZ3_RS02770	COG2966	Psort location CytoplasmicMembrane, score
YPZ3_RS02780	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPZ3_RS02830	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YPZ3_RS02835	COG0564	pseudouridine synthase activity
YPZ3_RS02925	COG2885	chlorophyll binding
YPZ3_RS02925	COG3047	cAMP biosynthetic process
YPZ3_RS02945	COG0417	DNA replication proofreading
YPZ3_RS02950	COG0586	Pfam SNARE associated Golgi protein
YPZ3_RS02955	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
YPZ3_RS02960	COG1178	ABC-type Fe3 transport system permease component
YPZ3_RS02965	COG4143	(ABC) transporter
YPZ3_RS02985	COG2814	Major facilitator Superfamily
YPZ3_RS03000	COG2814	Major facilitator Superfamily
YPZ3_RS03015	COG0473	3-isopropylmalate dehydrogenase activity
YPZ3_RS03045	COG1022	Amp-dependent synthetase and ligase
YPZ3_RS03055	COG0028	Belongs to the TPP enzyme family
YPZ3_RS03075	COG1609	Transcriptional regulator
YPZ3_RS03095	COG3116	cell division
YPZ3_RS03100	COG0768	penicillin binding
YPZ3_RS03105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPZ3_RS03110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPZ3_RS03125	COG0772	Belongs to the SEDS family
YPZ3_RS03145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPZ3_RS03150	COG0849	cell division
YPZ3_RS03155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPZ3_RS03180	COG0494	nUDIX hydrolase
YPZ3_RS03195	COG0435	Glutathione S-transferase
YPZ3_RS03200	COG2259	Doxx family
YPZ3_RS03210	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPZ3_RS03215	COG4575	ribosome binding
YPZ3_RS03235	COG0586	Pfam SNARE associated Golgi protein
YPZ3_RS03250	COG2271	Major facilitator Superfamily
YPZ3_RS03270	COG2721	sulfolactate sulfo-lyase activity
YPZ3_RS03290	COG0673	inositol 2-dehydrogenase activity
YPZ3_RS03295	COG1451	nucleotide metabolic process
YPZ3_RS03310	COG1902	pentaerythritol trinitrate reductase activity
YPZ3_RS03310	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPZ3_RS03315	COG3247	response to pH
YPZ3_RS03335	COG4245	von Willebrand factor, type A
YPZ3_RS03350	COG4245	von Willebrand factor, type A
YPZ3_RS03355	COG2831	hemolysin activation secretion protein
YPZ3_RS03360	COG3210	domain, Protein
YPZ3_RS03385	COG3210	domain, Protein
YPZ3_RS03390	COG3210	domain, Protein
YPZ3_RS03410	COG3842	ATPase activity
YPZ3_RS03415	COG3459	Glycosyltransferase 36 associated
YPZ3_RS03420	COG1609	Transcriptional regulator
YPZ3_RS03425	COG2182	Extracellular solute-binding protein
YPZ3_RS03435	COG0395	ABC-type sugar transport system, permease component
YPZ3_RS03455	COG1289	transmembrane transporter activity
YPZ3_RS03500	COG0251	oxidation-reduction process
YPZ3_RS03585	COG0358	DNA primase activity
YPZ3_RS03590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YPZ3_RS03605	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPZ3_RS03620	COG4991	sh3 domain protein
YPZ3_RS03625	COG3025	triphosphatase activity
YPZ3_RS03640	COG0531	amino acid
YPZ3_RS03660	COG3384	dioxygenase
YPZ3_RS03665	COG0754	glutathionylspermidine amidase activity
YPZ3_RS03680	COG1538	Outer membrane efflux protein
YPZ3_RS03685	COG0494	nUDIX hydrolase
YPZ3_RS03690	COG3151	Protein conserved in bacteria
YPZ3_RS03695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPZ3_RS03700	COG3150	esterase
YPZ3_RS03710	COG0583	DNA-binding transcription factor activity
YPZ3_RS03715	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPZ3_RS03720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPZ3_RS03730	COG2132	Multicopper oxidase
YPZ3_RS03740	COG0656	L-ascorbic acid biosynthetic process
YPZ3_RS03750	COG1979	alcohol dehydrogenase
YPZ3_RS03755	COG2207	Transcriptional regulator
YPZ3_RS03760	COG0586	Pfam SNARE associated Golgi protein
YPZ3_RS03765	COG0626	cystathionine gamma-synthase activity
YPZ3_RS03770	COG0811	peptide transport
YPZ3_RS03775	COG0848	biopolymer transport protein
YPZ3_RS03825	COG4964	Belongs to the GSP D family
YPZ3_RS03830	COG4964	Belongs to the GSP D family
YPZ3_RS03875	COG4592	Periplasmic binding protein
YPZ3_RS03895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPZ3_RS03900	COG1684	flagellar biosynthetic protein fliR
YPZ3_RS03905	COG1987	bacterial-type flagellum assembly
YPZ3_RS03930	COG1677	Flagellar hook-basal body complex protein FliE
YPZ3_RS03970	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPZ3_RS03975	COG1815	bacterial-type flagellum-dependent cell motility
YPZ3_RS03980	COG1558	bacterial-type flagellum-dependent cell motility
YPZ3_RS03985	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPZ3_RS03990	COG1749	Flagellar hook protein flgE
YPZ3_RS04015	COG4786	Flagellar basal body rod
YPZ3_RS04035	COG1256	bacterial-type flagellum assembly
YPZ3_RS04055	COG3710	Transcriptional regulator
YPZ3_RS04075	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YPZ3_RS04100	COG1191	sigma factor activity
YPZ3_RS04105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YPZ3_RS04150	COG2801	Transposase and inactivated derivatives
YPZ3_RS04155	COG5001	Diguanylate cyclase
YPZ3_RS04165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_RS04205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPZ3_RS04210	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPZ3_RS04215	COG4771	TonB-dependent receptor
YPZ3_RS04235	COG2226	methyltransferase
YPZ3_RS04235	COG3433	isochorismatase activity
YPZ3_RS04235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPZ3_RS04245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPZ3_RS04245	COG2226	methyltransferase
YPZ3_RS04245	COG3433	isochorismatase activity
YPZ3_RS04270	COG2375	cellular response to nickel ion
YPZ3_RS04270	COG1132	(ABC) transporter
YPZ3_RS04275	COG1132	(ABC) transporter
YPZ3_RS04290	COG2610	gluconate transmembrane transporter activity
YPZ3_RS04310	COG3501	Rhs element vgr protein
YPZ3_RS04320	COG3209	COG3209 Rhs family protein
YPZ3_RS04335	COG0471	metal ion transport
YPZ3_RS04350	COG2801	Transposase and inactivated derivatives
YPZ3_RS04360	COG2211	Major facilitator Superfamily
YPZ3_RS04410	COG2771	luxR family
YPZ3_RS04415	COG3916	Acyl-homoserine-lactone synthase
YPZ3_RS04520	COG1982	Orn Lys Arg decarboxylase major
YPZ3_RS04525	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_RS04530	COG1129	ABC transporter
YPZ3_RS04535	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS04540	COG4774	siderophore transport
YPZ3_RS04560	COG1194	a g-specific adenine glycosylase
YPZ3_RS04570	COG3171	Protein conserved in bacteria
YPZ3_RS04590	COG3064	Membrane
YPZ3_RS04590	COG1073	alpha beta
YPZ3_RS04590	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPZ3_RS04595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPZ3_RS04600	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPZ3_RS04610	COG0762	integral membrane protein
YPZ3_RS04615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPZ3_RS04620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPZ3_RS04625	COG2805	Type II/IV secretion system protein
YPZ3_RS04635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPZ3_RS04650	COG0189	ligase activity
YPZ3_RS04655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPZ3_RS04660	COG2356	endonuclease I
YPZ3_RS04675	COG1166	arginine decarboxylase activity
YPZ3_RS04685	COG0501	Belongs to the peptidase M48B family
YPZ3_RS04690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPZ3_RS04710	COG0191	fructose-bisphosphate aldolase activity
YPZ3_RS04745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPZ3_RS04750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPZ3_RS04765	COG0006	proline dipeptidase activity
YPZ3_RS04770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPZ3_RS04775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPZ3_RS04805	COG5295	Hep Hag repeat protein
YPZ3_RS04815	COG1272	protein, Hemolysin III
YPZ3_RS04840	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS04845	COG2205	protein histidine kinase activity
YPZ3_RS04850	COG4452	Inner membrane protein CreD
YPZ3_RS04855	COG0716	FMN binding
YPZ3_RS04860	COG4974	Belongs to the 'phage' integrase family
YPZ3_RS04865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPZ3_RS04870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPZ3_RS04890	COG0582	viral genome integration into host DNA
YPZ3_RS04920	COG2944	sequence-specific DNA binding
YPZ3_RS05015	COG1695	Transcriptional regulator
YPZ3_RS05020	COG0791	NLP P60 protein
YPZ3_RS05030	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_RS05035	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS05040	COG1129	ABC transporter
YPZ3_RS05050	COG2182	Extracellular solute-binding protein
YPZ3_RS05055	COG1175	transmembrane transport
YPZ3_RS05060	COG3833	ABC-type maltose transport systems, permease component
YPZ3_RS05065	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPZ3_RS05070	COG1874	Beta-galactosidase
YPZ3_RS05075	COG1263	PTS System
YPZ3_RS05075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_RS05095	COG2271	Major facilitator Superfamily
YPZ3_RS05125	COG3119	arylsulfatase activity
YPZ3_RS05130	COG0641	radical SAM
YPZ3_RS05140	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS05150	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_RS05155	COG3716	PTS system mannose fructose sorbose family IID component
YPZ3_RS05160	COG3715	PTS system
YPZ3_RS05165	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_RS05170	COG2222	sugar isomerase
YPZ3_RS05180	COG1349	DNA-binding transcription factor activity
YPZ3_RS05185	COG3119	arylsulfatase activity
YPZ3_RS05230	COG0288	reversible hydration of carbon dioxide
YPZ3_RS05250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPZ3_RS05320	COG0840	transmembrane signaling receptor activity
YPZ3_RS05335	COG0583	DNA-binding transcription factor activity
YPZ3_RS05340	COG2814	Major facilitator Superfamily
YPZ3_RS05345	COG0583	DNA-binding transcription factor activity
YPZ3_RS05355	COG1609	Transcriptional regulator
YPZ3_RS05385	COG0667	Aldo Keto reductase
YPZ3_RS05465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPZ3_RS05475	COG1074	ATP-dependent DNA helicase activity
YPZ3_RS05480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPZ3_RS05490	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPZ3_RS05505	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPZ3_RS05510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPZ3_RS05515	COG2166	iron-sulfur cluster assembly
YPZ3_RS05520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPZ3_RS05525	COG0583	DNA-binding transcription factor activity
YPZ3_RS05530	COG2363	Small membrane protein
YPZ3_RS05545	COG1611	Belongs to the LOG family
YPZ3_RS05565	COG3098	single-species biofilm formation
YPZ3_RS05570	COG0564	pseudouridine synthase activity
YPZ3_RS05630	COG0575	Belongs to the CDS family
YPZ3_RS05635	COG0750	zinc metalloprotease
YPZ3_RS05650	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPZ3_RS05675	COG0587	DNA-directed DNA polymerase activity
YPZ3_RS05685	COG0346	lactoylglutathione lyase activity
YPZ3_RS05690	COG0037	tRNA processing
YPZ3_RS05700	COG4568	rho-dependent transcription termination
YPZ3_RS05710	COG4681	YaeQ
YPZ3_RS05720	COG3015	lipoprotein NlpE involved in copper resistance
YPZ3_RS05730	COG1720	tRNA m6t6A37 methyltransferase activity
YPZ3_RS05740	COG1464	Belongs to the NlpA lipoprotein family
YPZ3_RS05745	COG2011	ABC-type metal ion transport system permease component
YPZ3_RS05755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPZ3_RS05790	COG0656	L-ascorbic acid biosynthetic process
YPZ3_RS05805	COG0741	lytic transglycosylase activity
YPZ3_RS05805	COG1388	LysM domain
YPZ3_RS05810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPZ3_RS05835	COG1953	Uracil, thiamine, allantoin
YPZ3_RS05865	COG3657	addiction module killer protein
YPZ3_RS05925	COG0582	viral genome integration into host DNA
YPZ3_RS05945	COG2867	negative regulation of translational initiation
YPZ3_RS05955	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPZ3_RS05960	COG0497	DNA recombination
YPZ3_RS05965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YPZ3_RS05980	COG2009	succinate dehydrogenase
YPZ3_RS05985	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPZ3_RS05990	COG1053	succinate dehydrogenase
YPZ3_RS06000	COG0567	Dehydrogenase, E1 component
YPZ3_RS06005	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPZ3_RS06015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPZ3_RS06020	COG1271	oxidase subunit
YPZ3_RS06025	COG1294	oxidase, subunit
YPZ3_RS06030	COG4890	Cyd operon protein YbgT
YPZ3_RS06035	COG3790	cyd operon protein YbgE
YPZ3_RS06040	COG0824	Thioesterase
YPZ3_RS06045	COG0811	peptide transport
YPZ3_RS06050	COG0848	biopolymer transport protein
YPZ3_RS06055	COG3064	Membrane
YPZ3_RS06055	COG3064	Membrane
YPZ3_RS06065	COG2885	chlorophyll binding
YPZ3_RS06070	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPZ3_RS06100	COG1230	cation diffusion facilitator family transporter
YPZ3_RS06105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPZ3_RS06120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPZ3_RS06135	COG2017	converts alpha-aldose to the beta-anomer
YPZ3_RS06150	COG1085	galactose-1-phosphate uridylyltransferase
YPZ3_RS06155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPZ3_RS06170	COG1119	ATPase activity
YPZ3_RS06175	COG3585	molybdate ion transport
YPZ3_RS06175	COG2005	Transcriptional regulator
YPZ3_RS06185	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPZ3_RS06190	COG4149	molybdate abc transporter
YPZ3_RS06200	COG0561	phosphatase activity
YPZ3_RS06225	COG2226	methyltransferase
YPZ3_RS06235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YPZ3_RS06245	COG4628	conserved protein (DUF2132)
YPZ3_RS06250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPZ3_RS06260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPZ3_RS06270	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPZ3_RS06275	COG0314	molybdopterin synthase activity
YPZ3_RS06280	COG0670	Belongs to the BI1 family
YPZ3_RS06310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPZ3_RS06315	COG0583	DNA-binding transcription factor activity
YPZ3_RS06325	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPZ3_RS06330	COG2211	Major facilitator Superfamily
YPZ3_RS06340	COG2211	Major facilitator Superfamily
YPZ3_RS06360	COG1902	pentaerythritol trinitrate reductase activity
YPZ3_RS06380	COG0842	Transport permease protein
YPZ3_RS06385	COG0842	Transport permease protein
YPZ3_RS06390	COG1131	(ABC) transporter
YPZ3_RS06400	COG1309	transcriptional regulator
YPZ3_RS06405	COG0513	Belongs to the DEAD box helicase family
YPZ3_RS06430	COG3328	transposase activity
YPZ3_RS06440	COG0513	Belongs to the DEAD box helicase family
YPZ3_RS06460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPZ3_RS06470	COG1686	Belongs to the peptidase S11 family
YPZ3_RS06475	COG0277	FAD linked oxidase domain protein
YPZ3_RS06495	COG2261	transglycosylase associated protein
YPZ3_RS06505	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPZ3_RS06520	COG4807	Protein conserved in bacteria
YPZ3_RS06540	COG1122	ATPase activity
YPZ3_RS06560	COG2897	thiosulfate sulfurtransferase activity
YPZ3_RS06565	COG1732	Glycine betaine
YPZ3_RS06570	COG1732	Glycine betaine
YPZ3_RS06575	COG1174	glycine betaine transport
YPZ3_RS06580	COG1125	glycine betaine transport
YPZ3_RS06585	COG1174	glycine betaine transport
YPZ3_RS06590	COG0531	amino acid
YPZ3_RS06595	COG1982	Orn Lys Arg decarboxylase major
YPZ3_RS06605	COG0697	spore germination
YPZ3_RS06630	COG0814	amino acid
YPZ3_RS06645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_RS06675	COG0784	Response regulator, receiver
YPZ3_RS06675	COG2205	protein histidine kinase activity
YPZ3_RS06685	COG0642	Histidine kinase
YPZ3_RS06685	COG2198	Histidine kinase
YPZ3_RS06690	COG2198	Histidine kinase
YPZ3_RS06690	COG0642	Histidine kinase
YPZ3_RS06695	COG2223	nitrite transmembrane transporter activity
YPZ3_RS06725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPZ3_RS06770	COG3395	kinase activity
YPZ3_RS06780	COG1349	DNA-binding transcription factor activity
YPZ3_RS06785	COG3622	Belongs to the hyi family
YPZ3_RS06805	COG4386	tail sheath protein
YPZ3_RS06845	COG3299	homolog of phage Mu protein gp47
YPZ3_RS06865	COG1737	Transcriptional regulator
YPZ3_RS06870	COG2723	6-phospho-beta-galactosidase activity
YPZ3_RS06890	COG3157	Type VI secretion system effector, Hcp
YPZ3_RS06905	COG3083	sulfuric ester hydrolase activity
YPZ3_RS06910	COG3082	Protein of unknown function (DUF1414)
YPZ3_RS06935	COG1061	Type III restriction enzyme res subunit
YPZ3_RS06940	COG1187	pseudouridine synthase activity
YPZ3_RS06945	COG2814	Major facilitator Superfamily
YPZ3_RS06955	COG4172	Belongs to the ABC transporter superfamily
YPZ3_RS06960	COG4239	(ABC) transporter, permease
YPZ3_RS06965	COG4174	ABC transporter (Permease)
YPZ3_RS06970	COG4166	transmembrane transport
YPZ3_RS06975	COG2200	EAL domain
YPZ3_RS06980	COG0791	NLP P60 protein
YPZ3_RS06985	COG0671	phosphoesterase, PA-phosphatase related
YPZ3_RS06990	COG0523	cobalamin synthesis protein
YPZ3_RS07000	COG2186	Transcriptional regulator
YPZ3_RS07005	COG0246	Mannitol dehydrogenase
YPZ3_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS07065	COG1129	ABC transporter
YPZ3_RS07075	COG0494	nUDIX hydrolase
YPZ3_RS07085	COG1105	Belongs to the carbohydrate kinase PfkB family
YPZ3_RS07090	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPZ3_RS07090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_RS07090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPZ3_RS07095	COG3710	Transcriptional regulator
YPZ3_RS07110	COG3121	Chaperone
YPZ3_RS07115	COG3188	usher protein
YPZ3_RS07125	COG2855	membrane
YPZ3_RS07130	COG0583	DNA-binding transcription factor activity
YPZ3_RS07135	COG0833	amino acid
YPZ3_RS07145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_RS07155	COG4771	TonB-dependent receptor
YPZ3_RS07160	COG0625	glutathione transferase activity
YPZ3_RS07185	COG2011	ABC-type metal ion transport system permease component
YPZ3_RS07190	COG1686	Belongs to the peptidase S11 family
YPZ3_RS07200	COG0814	amino acid
YPZ3_RS07205	COG1349	DNA-binding transcription factor activity
YPZ3_RS07215	COG0671	phosphoesterase, PA-phosphatase related
YPZ3_RS07250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPZ3_RS07255	COG3842	ATPase activity
YPZ3_RS07260	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPZ3_RS07265	COG1177	transmembrane transport
YPZ3_RS07280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_RS07310	COG1120	ATPase activity
YPZ3_RS07335	COG4160	amino acid transport
YPZ3_RS07340	COG4215	(ABC) transporter
YPZ3_RS07345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_RS07350	COG1126	abc transporter atp-binding protein
YPZ3_RS07355	COG1605	Chorismate mutase
YPZ3_RS07365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_RS07370	COG0702	epimerase
YPZ3_RS07375	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPZ3_RS07380	COG0028	Belongs to the TPP enzyme family
YPZ3_RS07385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_RS07395	COG2431	L-lysine efflux transmembrane transporter activity
YPZ3_RS07400	COG3593	DNA synthesis involved in DNA repair
YPZ3_RS07405	COG2990	Protein conserved in bacteria
YPZ3_RS07410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_RS07420	COG1278	Cold shock
YPZ3_RS07430	COG0542	response to heat
YPZ3_RS07440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPZ3_RS07450	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPZ3_RS07465	COG0492	ferredoxin-NADP+ reductase activity
YPZ3_RS07475	COG3107	peptidoglycan biosynthetic process
YPZ3_RS07475	COG1674	ftsk spoiiie
YPZ3_RS07485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPZ3_RS07500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPZ3_RS07510	COG1882	Formate acetyltransferase
YPZ3_RS07515	COG2116	formate transmembrane transporter activity
YPZ3_RS07520	COG1944	ATP diphosphatase activity
YPZ3_RS07525	COG0252	asparaginase activity
YPZ3_RS07530	COG5295	Hep Hag repeat protein
YPZ3_RS07530	COG5295	Hep Hag repeat protein
YPZ3_RS07555	COG0539	negative regulation of cytoplasmic translation
YPZ3_RS07570	COG0658	competence protein
YPZ3_RS07570	COG2333	competence protein COMEC
YPZ3_RS07585	COG5383	Protein conserved in bacteria
YPZ3_RS07595	COG1278	Cold shock
YPZ3_RS07610	COG3173	Aminoglycoside phosphotransferase
YPZ3_RS07620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPZ3_RS07650	COG2989	Protein conserved in bacteria
YPZ3_RS07655	COG3108	Peptidase M15
YPZ3_RS07660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPZ3_RS07665	COG1448	Aminotransferase
YPZ3_RS07685	COG0308	aminopeptidase N
YPZ3_RS07700	COG0633	Ferredoxin
YPZ3_RS07700	COG3217	Mosc domain protein beta barrel domain protein
YPZ3_RS07710	COG0488	(ABC) transporter
YPZ3_RS07715	COG2995	paraquat-inducible protein a
YPZ3_RS07720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPZ3_RS07720	COG3008	intermembrane lipid transfer
YPZ3_RS07725	COG3009	Protein conserved in bacteria
YPZ3_RS07735	COG3130	regulation of translation
YPZ3_RS07750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_RS07765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_RS07780	COG1067	ATP-dependent peptidase activity
YPZ3_RS07810	COG3070	regulator of competence-specific genes
YPZ3_RS07815	COG1289	transmembrane transporter activity
YPZ3_RS07820	COG3304	Inner membrane component domain
YPZ3_RS07825	COG0210	DNA helicase
YPZ3_RS07840	COG1832	CoA-binding protein
YPZ3_RS07860	COG2920	part of a sulfur-relay system
YPZ3_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS07905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPZ3_RS07910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_RS07915	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS07920	COG3425	synthase
YPZ3_RS07930	COG1024	Enoyl-CoA hydratase
YPZ3_RS07935	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS07945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPZ3_RS07950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPZ3_RS08115	COG0488	(ABC) transporter
YPZ3_RS08125	COG3328	transposase activity
YPZ3_RS08135	COG0303	'Molybdopterin
YPZ3_RS08145	COG1136	(ABC) transporter
YPZ3_RS08180	COG0583	DNA-binding transcription factor activity
YPZ3_RS08185	COG0477	Major facilitator Superfamily
YPZ3_RS08195	COG2311	Membrane
YPZ3_RS08210	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS08215	COG2949	membrane
YPZ3_RS08230	COG1346	cytolysis
YPZ3_RS08240	COG2814	Major facilitator Superfamily
YPZ3_RS08275	COG0489	protein tyrosine kinase activity
YPZ3_RS08290	COG2982	Protein involved in outer membrane biogenesis
YPZ3_RS08295	COG1253	flavin adenine dinucleotide binding
YPZ3_RS08300	COG4114	ferric iron reductase
YPZ3_RS08305	COG0076	glutamate decarboxylase activity
YPZ3_RS08310	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPZ3_RS08325	COG1120	ATPase activity
YPZ3_RS08330	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_RS08335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_RS08340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPZ3_RS08355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPZ3_RS08360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPZ3_RS08370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPZ3_RS08370	COG0140	phosphoribosyl-ATP diphosphatase activity
YPZ3_RS08390	COG0131	Imidazoleglycerol-phosphate dehydratase
YPZ3_RS08390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPZ3_RS08400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPZ3_RS08410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_RS08420	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS08425	COG1129	ABC transporter
YPZ3_RS08430	COG1129	ABC transporter
YPZ3_RS08435	COG0371	Dehydrogenase
YPZ3_RS08445	COG0531	amino acid
YPZ3_RS08450	COG2925	Exonuclease
YPZ3_RS08465	COG3328	transposase activity
YPZ3_RS08470	COG1388	LysM domain
YPZ3_RS08470	COG1470	cell adhesion involved in biofilm formation
YPZ3_RS08475	COG2271	Major facilitator Superfamily
YPZ3_RS08480	COG3011	Protein conserved in bacteria
YPZ3_RS08485	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS08495	COG4948	Mandelate Racemase Muconate Lactonizing
YPZ3_RS08510	COG0534	Mate efflux family protein
YPZ3_RS08530	COG3122	Protein conserved in bacteria
YPZ3_RS08555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPZ3_RS08575	COG2223	nitrite transmembrane transporter activity
YPZ3_RS08580	COG3328	transposase activity
YPZ3_RS08585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPZ3_RS08595	COG3001	Fructosamine kinase
YPZ3_RS08605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPZ3_RS08610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPZ3_RS08615	COG1121	(ABC) transporter
YPZ3_RS08620	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPZ3_RS08645	COG4249	Peptidase C14 caspase catalytic subunit p20
YPZ3_RS08675	COG0072	phenylalanine-tRNA ligase activity
YPZ3_RS08675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YPZ3_RS08680	COG0776	regulation of translation
YPZ3_RS08695	COG0386	Belongs to the glutathione peroxidase family
YPZ3_RS08740	COG0791	NLP P60 protein
YPZ3_RS08765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPZ3_RS08765	COG0574	Belongs to the PEP-utilizing enzyme family
YPZ3_RS08770	COG0628	permease
YPZ3_RS08775	COG0277	FAD linked oxidase domain protein
YPZ3_RS08775	COG0247	lactate metabolic process
YPZ3_RS08780	COG2050	protein possibly involved in aromatic compounds catabolism
YPZ3_RS08790	COG0316	Belongs to the HesB IscA family
YPZ3_RS08795	COG0719	Fe-S assembly protein
YPZ3_RS08800	COG0396	ATPase activity
YPZ3_RS08805	COG0719	Fe-S assembly protein
YPZ3_RS08820	COG1376	ErfK ybiS ycfS ynhG family protein
YPZ3_RS08820	COG1388	LysM domain
YPZ3_RS08870	COG0307	riboflavin synthase, alpha
YPZ3_RS08875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPZ3_RS08880	COG2814	Major facilitator Superfamily
YPZ3_RS08885	COG0583	DNA-binding transcription factor activity
YPZ3_RS08900	COG0791	NLP P60 protein
YPZ3_RS08910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPZ3_RS08915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPZ3_RS08920	COG0346	lactoylglutathione lyase activity
YPZ3_RS08930	COG1902	pentaerythritol trinitrate reductase activity
YPZ3_RS08935	COG1309	transcriptional regulator
YPZ3_RS08940	COG2194	sulfuric ester hydrolase activity
YPZ3_RS08945	COG3313	Fe-S protein
YPZ3_RS08950	COG4989	oxidoreductase activity
YPZ3_RS08960	COG3133	Outer membrane lipoprotein
YPZ3_RS08970	COG3895	Periplasmic Protein
YPZ3_RS08990	COG0625	glutathione transferase activity
YPZ3_RS09005	COG3104	oligopeptide transport
YPZ3_RS09010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPZ3_RS09010	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPZ3_RS09015	COG4172	Belongs to the ABC transporter superfamily
YPZ3_RS09025	COG4171	peptide transport system, permease
YPZ3_RS09030	COG4168	peptide transport system, permease
YPZ3_RS09035	COG4166	transmembrane transport
YPZ3_RS09055	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPZ3_RS09060	COG1842	Phage shock protein A
YPZ3_RS09070	COG1983	PspC domain protein
YPZ3_RS09080	COG3106	COG3106 Predicted ATPase
YPZ3_RS09090	COG5654	RES domain protein
YPZ3_RS09095	COG5642	Protein of unknown function (DUF2384)
YPZ3_RS09110	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPZ3_RS09115	COG4948	Mandelate Racemase Muconate Lactonizing
YPZ3_RS09120	COG2866	Carboxypeptidase
YPZ3_RS09125	COG4166	transmembrane transport
YPZ3_RS09140	COG0657	acetylesterase activity
YPZ3_RS09150	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPZ3_RS09150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPZ3_RS09150	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPZ3_RS09150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPZ3_RS09160	COG1285	pathogenesis
YPZ3_RS09165	COG3042	response to heat
YPZ3_RS09170	COG3187	Heat shock protein
YPZ3_RS09175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPZ3_RS09180	COG2911	Protein conserved in bacteria
YPZ3_RS09190	COG3784	Protein of unknown function (DUF1318)
YPZ3_RS09195	COG0246	Mannitol dehydrogenase
YPZ3_RS09200	COG2390	Transcriptional regulator
YPZ3_RS09210	COG1643	Atp-dependent helicase
YPZ3_RS09225	COG3591	Belongs to the peptidase S1B family
YPZ3_RS09240	COG3038	cytochrome b561
YPZ3_RS09275	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPZ3_RS09280	COG2205	protein histidine kinase activity
YPZ3_RS09285	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS09295	COG0531	amino acid
YPZ3_RS09310	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPZ3_RS09315	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPZ3_RS09320	COG0589	response to stress
YPZ3_RS09325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPZ3_RS09330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPZ3_RS09350	COG1011	Hydrolase
YPZ3_RS09355	COG0440	acetolactate synthase activity
YPZ3_RS09360	COG0028	Belongs to the TPP enzyme family
YPZ3_RS09385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPZ3_RS09400	COG1609	Transcriptional regulator
YPZ3_RS09410	COG0038	chloride channel
YPZ3_RS09415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPZ3_RS09420	COG1940	carbohydrate kinase activity
YPZ3_RS09425	COG0583	DNA-binding transcription factor activity
YPZ3_RS09440	COG0114	fumarate hydratase activity
YPZ3_RS09450	COG5339	Protein conserved in bacteria
YPZ3_RS09460	COG0385	Bile acid
YPZ3_RS09465	COG0673	inositol 2-dehydrogenase activity
YPZ3_RS09475	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS09480	COG1129	ABC transporter
YPZ3_RS09485	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_RS09500	COG2274	protein secretion by the type I secretion system
YPZ3_RS09505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_RS09515	COG1132	(ABC) transporter
YPZ3_RS09545	COG3708	Transcriptional regulator
YPZ3_RS09545	COG2207	Transcriptional regulator
YPZ3_RS09550	COG4658	electron transport chain
YPZ3_RS09555	COG4659	FMN binding
YPZ3_RS09565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPZ3_RS09570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_RS09575	COG2271	Major facilitator Superfamily
YPZ3_RS09585	COG1966	Carbon starvation protein
YPZ3_RS09590	COG2879	small protein
YPZ3_RS09595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPZ3_RS09615	COG0023	Translation Initiation Factor
YPZ3_RS09630	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPZ3_RS09635	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPZ3_RS09640	COG0671	phosphoesterase, PA-phosphatase related
YPZ3_RS09650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPZ3_RS09660	COG0583	DNA-binding transcription factor activity
YPZ3_RS09680	COG0616	signal peptide processing
YPZ3_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS09695	COG1187	pseudouridine synthase activity
YPZ3_RS09700	COG0009	L-threonylcarbamoyladenylate synthase
YPZ3_RS09725	COG0512	Glutamine amidotransferase of anthranilate synthase
YPZ3_RS09735	COG0134	indole-3-glycerol-phosphate synthase activity
YPZ3_RS09735	COG0135	phosphoribosylanthranilate isomerase activity
YPZ3_RS09755	COG3047	cAMP biosynthetic process
YPZ3_RS09790	COG3328	transposase activity
YPZ3_RS09795	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPZ3_RS09800	COG2350	Protein conserved in bacteria
YPZ3_RS09840	COG4608	Belongs to the ABC transporter superfamily
YPZ3_RS09845	COG0444	Belongs to the ABC transporter superfamily
YPZ3_RS09850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPZ3_RS09855	COG0601	transmembrane transport
YPZ3_RS09865	COG2095	MarC family integral membrane protein
YPZ3_RS09870	COG1454	alcohol dehydrogenase
YPZ3_RS09870	COG1012	belongs to the aldehyde dehydrogenase family
YPZ3_RS09900	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS09910	COG0788	formyltetrahydrofolate deformylase activity
YPZ3_RS09915	COG3328	transposase activity
YPZ3_RS09925	COG0583	DNA-binding transcription factor activity
YPZ3_RS09930	COG0708	Exodeoxyribonuclease III
YPZ3_RS09935	COG0494	nUDIX hydrolase
YPZ3_RS09945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPZ3_RS09950	COG0709	Synthesizes selenophosphate from selenide and ATP
YPZ3_RS09955	COG0778	Nitroreductase
YPZ3_RS09960	COG0616	signal peptide processing
YPZ3_RS09965	COG0252	asparaginase activity
YPZ3_RS09970	COG1335	isochorismatase
YPZ3_RS09975	COG3139	Protein of unknown function (DUF1315)
YPZ3_RS09995	COG3713	MltA-interacting MipA family protein
YPZ3_RS10000	COG2766	serine protein kinase
YPZ3_RS10015	COG0583	DNA-binding transcription factor activity
YPZ3_RS10025	COG2814	Major facilitator Superfamily
YPZ3_RS10035	COG2719	SpoVR family
YPZ3_RS10065	COG1104	cysteine desulfurase activity
YPZ3_RS10075	COG3328	transposase activity
YPZ3_RS10250	COG3328	transposase activity
YPZ3_RS10350	COG0582	viral genome integration into host DNA
YPZ3_RS10360	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPZ3_RS10365	COG2951	lytic endotransglycosylase activity
YPZ3_RS10380	COG2894	cell division
YPZ3_RS10385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPZ3_RS10390	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPZ3_RS10395	COG0318	PFAM AMP-dependent synthetase and ligase
YPZ3_RS10400	COG3065	identical protein binding
YPZ3_RS10410	COG1199	ATP-dependent helicase activity
YPZ3_RS10415	COG0251	oxidation-reduction process
YPZ3_RS10430	COG0800	Aldolase
YPZ3_RS10435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPZ3_RS10440	COG1737	Transcriptional regulator
YPZ3_RS10445	COG0469	pyruvate kinase activity
YPZ3_RS10450	COG1560	Kdo2-lipid A biosynthetic process
YPZ3_RS10455	COG0739	heme binding
YPZ3_RS10460	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPZ3_RS10470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPZ3_RS10495	COG0494	nUDIX hydrolase
YPZ3_RS10505	COG1801	Protein of unknown function DUF72
YPZ3_RS10510	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPZ3_RS10530	COG3102	Protein conserved in bacteria
YPZ3_RS10550	COG0728	peptidoglycan biosynthetic process
YPZ3_RS10555	COG0673	inositol 2-dehydrogenase activity
YPZ3_RS10560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPZ3_RS10575	COG3381	protein complex oligomerization
YPZ3_RS10590	COG1940	carbohydrate kinase activity
YPZ3_RS10595	COG0584	glycerophosphoryl diester phosphodiesterase
YPZ3_RS10600	COG3842	ATPase activity
YPZ3_RS10615	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPZ3_RS10620	COG3833	ABC-type maltose transport systems, permease component
YPZ3_RS10645	COG0659	secondary active sulfate transmembrane transporter activity
YPZ3_RS10665	COG2890	protein-(glutamine-N5) methyltransferase activity
YPZ3_RS10695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPZ3_RS10715	COG0012	GTP binding
YPZ3_RS10770	COG5002	protein histidine kinase activity
YPZ3_RS10810	COG0500	methyltransferase
YPZ3_RS10835	COG3328	transposase activity
YPZ3_RS10880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_RS10885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPZ3_RS10890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPZ3_RS10905	COG0402	S-adenosylhomocysteine deaminase activity
YPZ3_RS10960	COG3842	ATPase activity
YPZ3_RS10965	COG0395	ABC-type sugar transport system, permease component
YPZ3_RS10970	COG1175	transmembrane transport
YPZ3_RS10980	COG0673	inositol 2-dehydrogenase activity
YPZ3_RS10990	COG2188	Transcriptional regulator
YPZ3_RS11130	COG2197	response regulator
YPZ3_RS11140	COG3136	membrane protein required for alginate biosynthesis
YPZ3_RS11160	COG1113	amino acid transport
YPZ3_RS11180	COG2822	iron ion transport
YPZ3_RS11185	COG0672	)-iron permease
YPZ3_RS11200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPZ3_RS11200	COG0506	proline dehydrogenase activity
YPZ3_RS11200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPZ3_RS11215	COG1126	abc transporter atp-binding protein
YPZ3_RS11220	COG0765	amino acid transport
YPZ3_RS11225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_RS11240	COG1191	sigma factor activity
YPZ3_RS11275	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YPZ3_RS11280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPZ3_RS11285	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPZ3_RS11300	COG1677	Flagellar hook-basal body complex protein FliE
YPZ3_RS11320	COG1157	protein secretion by the type III secretion system
YPZ3_RS11335	COG1580	Controls the rotational direction of flagella during chemotaxis
YPZ3_RS11380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_RS11385	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS11390	COG1129	ABC transporter
YPZ3_RS11400	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS11405	COG3347	Dehydrogenase
YPZ3_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS11410	COG2390	Transcriptional regulator
YPZ3_RS11420	COG1256	bacterial-type flagellum assembly
YPZ3_RS11460	COG1558	bacterial-type flagellum-dependent cell motility
YPZ3_RS11465	COG1815	bacterial-type flagellum-dependent cell motility
YPZ3_RS11475	COG2747	anti-sigma28 factor FlgM
YPZ3_RS11480	COG3418	PFAM FlgN family protein
YPZ3_RS11505	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPZ3_RS11510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPZ3_RS11540	COG2372	response to copper ion
YPZ3_RS11545	COG1528	Iron-storage protein
YPZ3_RS11560	COG1770	oligopeptidase
YPZ3_RS11575	COG3141	response to X-ray
YPZ3_RS11580	COG0513	Belongs to the DEAD box helicase family
YPZ3_RS11605	COG1760	l-serine dehydratase
YPZ3_RS11610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPZ3_RS11615	COG2368	4-hydroxyphenylacetate
YPZ3_RS11630	COG3971	2-oxopent-4-enoate hydratase activity
YPZ3_RS11640	COG3384	dioxygenase
YPZ3_RS11645	COG1012	belongs to the aldehyde dehydrogenase family
YPZ3_RS11660	COG1846	Transcriptional regulator
YPZ3_RS11665	COG1253	flavin adenine dinucleotide binding
YPZ3_RS11670	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_RS11670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_RS11675	COG3715	PTS system
YPZ3_RS11680	COG3716	PTS system mannose fructose sorbose family IID component
YPZ3_RS11700	COG5001	Diguanylate cyclase
YPZ3_RS11700	COG5002	protein histidine kinase activity
YPZ3_RS11700	COG3447	MASE1 domain protein
YPZ3_RS11710	COG2226	methyltransferase
YPZ3_RS11715	COG1496	oxidoreductase activity
YPZ3_RS11740	COG1113	amino acid transport
YPZ3_RS11775	COG2207	Transcriptional regulator
YPZ3_RS11785	COG1132	(ABC) transporter
YPZ3_RS11830	COG3328	transposase activity
YPZ3_RS11835	COG1917	Cupin 2, conserved barrel domain protein
YPZ3_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS11855	COG1175	transmembrane transport
YPZ3_RS11860	COG0395	ABC-type sugar transport system, permease component
YPZ3_RS11865	COG3842	ATPase activity
YPZ3_RS11870	COG1653	transport
YPZ3_RS11875	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPZ3_RS11880	COG1988	membrane-bound metal-dependent
YPZ3_RS11885	COG1823	symporter activity
YPZ3_RS11890	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPZ3_RS11900	COG0823	Involved in the tonB-independent uptake of proteins
YPZ3_RS11905	COG2814	Major facilitator Superfamily
YPZ3_RS11910	COG3121	Chaperone
YPZ3_RS11925	COG3121	Chaperone
YPZ3_RS11930	COG3539	Fimbrial protein
YPZ3_RS11940	COG0793	Belongs to the peptidase S41A family
YPZ3_RS11950	COG1956	GAF domain-containing protein
YPZ3_RS11955	COG2995	paraquat-inducible protein a
YPZ3_RS11960	COG3008	intermembrane lipid transfer
YPZ3_RS11980	COG3121	Chaperone
YPZ3_RS12035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPZ3_RS12045	COG5295	Hep Hag repeat protein
YPZ3_RS12055	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPZ3_RS12065	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPZ3_RS12070	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS12080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPZ3_RS12085	COG0840	transmembrane signaling receptor activity
YPZ3_RS12090	COG0840	transmembrane signaling receptor activity
YPZ3_RS12110	COG2964	Protein conserved in bacteria
YPZ3_RS12120	COG0251	oxidation-reduction process
YPZ3_RS12125	COG2271	Major facilitator Superfamily
YPZ3_RS12130	COG0835	chemotaxis
YPZ3_RS12135	COG2198	Histidine kinase
YPZ3_RS12135	COG0643	Histidine kinase
YPZ3_RS12140	COG1360	Flagellar Motor Protein
YPZ3_RS12165	COG1285	pathogenesis
YPZ3_RS12195	COG3321	synthase
YPZ3_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS12195	COG0604	alcohol dehydrogenase
YPZ3_RS12205	COG1522	sequence-specific DNA binding
YPZ3_RS12230	COG1733	regulation of RNA biosynthetic process
YPZ3_RS12235	COG0702	epimerase
YPZ3_RS12240	COG0840	transmembrane signaling receptor activity
YPZ3_RS12255	COG0538	isocitrate dehydrogenase activity
YPZ3_RS12260	COG1187	pseudouridine synthase activity
YPZ3_RS12280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPZ3_RS12290	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS12300	COG2850	peptidyl-arginine hydroxylation
YPZ3_RS12315	COG1940	carbohydrate kinase activity
YPZ3_RS12320	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPZ3_RS12330	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPZ3_RS12335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPZ3_RS12340	COG3134	Outer membrane lipoprotein
YPZ3_RS12345	COG3328	transposase activity
YPZ3_RS12360	COG1252	NADH dehydrogenase
YPZ3_RS12370	COG1472	Belongs to the glycosyl hydrolase 3 family
YPZ3_RS12385	COG5633	Lipoprotein
YPZ3_RS12390	COG0537	adenosine 5'-monophosphoramidase activity
YPZ3_RS12395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPZ3_RS12405	COG1263	PTS System
YPZ3_RS12405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_RS12410	COG0084	hydrolase, TatD family'
YPZ3_RS12415	COG0470	DNA polymerase III
YPZ3_RS12425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPZ3_RS12430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPZ3_RS12440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_RS12470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPZ3_RS12475	COG1399	metal-binding, possibly nucleic acid-binding protein
YPZ3_RS12480	COG0424	maF-like protein
YPZ3_RS12495	COG0564	pseudouridine synthase activity
YPZ3_RS12500	COG1530	ribonuclease E activity
YPZ3_RS12505	COG3328	transposase activity
YPZ3_RS12510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPZ3_RS12535	COG3328	transposase activity
YPZ3_RS12550	COG0628	permease
YPZ3_RS12580	COG3916	Acyl-homoserine-lactone synthase
YPZ3_RS12585	COG2771	luxR family
YPZ3_RS12590	COG0583	DNA-binding transcription factor activity
YPZ3_RS12600	COG0477	Major facilitator Superfamily
YPZ3_RS12610	COG0667	Aldo Keto reductase
YPZ3_RS12635	COG1203	CRISPR-associated helicase, Cas3
YPZ3_RS12640	COG1518	maintenance of DNA repeat elements
YPZ3_RS12645	COG0668	transmembrane transport
YPZ3_RS12665	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPZ3_RS12670	COG0395	ABC-type sugar transport system, permease component
YPZ3_RS12685	COG1609	Transcriptional regulator
YPZ3_RS12695	COG3842	ATPase activity
YPZ3_RS12705	COG3210	domain, Protein
YPZ3_RS12725	COG3210	domain, Protein
YPZ3_RS12745	COG3210	domain, Protein
YPZ3_RS12750	COG2831	hemolysin activation secretion protein
YPZ3_RS12755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_RS12760	COG4638	Rieske (2fe-2S)
YPZ3_RS12765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPZ3_RS12775	COG0473	3-isopropylmalate dehydrogenase activity
YPZ3_RS12780	COG0583	DNA-binding transcription factor activity
YPZ3_RS12785	COG1609	Transcriptional regulator
YPZ3_RS12790	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS12795	COG1129	ABC transporter
YPZ3_RS12800	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_RS12805	COG1063	alcohol dehydrogenase
YPZ3_RS12825	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPZ3_RS12855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_RS12860	COG0765	amino acid transport
YPZ3_RS12865	COG1126	abc transporter atp-binding protein
YPZ3_RS12890	COG2271	Major facilitator Superfamily
YPZ3_RS12905	COG2831	hemolysin activation secretion protein
YPZ3_RS12915	COG0747	negative chemotaxis
YPZ3_RS12920	COG0601	transmembrane transport
YPZ3_RS12925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPZ3_RS12930	COG0444	Belongs to the ABC transporter superfamily
YPZ3_RS12935	COG4608	Belongs to the ABC transporter superfamily
YPZ3_RS12940	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPZ3_RS12945	COG2199	diguanylate cyclase activity
YPZ3_RS12945	COG2200	EAL domain
YPZ3_RS12950	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPZ3_RS12970	COG0612	Peptidase, M16
YPZ3_RS12975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_RS12980	COG1942	4-Oxalocrotonate Tautomerase
YPZ3_RS12985	COG2200	EAL domain
YPZ3_RS12990	COG2982	Protein involved in outer membrane biogenesis
YPZ3_RS12995	COG2134	cdp-diacylglycerol pyrophosphatase
YPZ3_RS13000	COG1295	ribonuclease BN
YPZ3_RS13025	COG1929	Belongs to the glycerate kinase type-1 family
YPZ3_RS13030	COG2610	gluconate transmembrane transporter activity
YPZ3_RS13035	COG3835	regulator
YPZ3_RS13040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPZ3_RS13045	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPZ3_RS13050	COG0339	signal peptide processing
YPZ3_RS13070	COG0589	response to stress
YPZ3_RS13090	COG0306	phosphate transporter
YPZ3_RS13095	COG2081	HI0933 family
YPZ3_RS13110	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS13125	COG0191	fructose-bisphosphate aldolase activity
YPZ3_RS13145	COG1741	Belongs to the pirin family
YPZ3_RS13150	COG1609	Transcriptional regulator
YPZ3_RS13155	COG2610	gluconate transmembrane transporter activity
YPZ3_RS13160	COG3265	gluconokinase activity
YPZ3_RS13180	COG2095	MarC family integral membrane protein
YPZ3_RS13185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPZ3_RS13215	COG3275	phosphorelay sensor kinase activity
YPZ3_RS13240	COG0058	SHG alpha-glucan phosphorylase activity
YPZ3_RS13245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPZ3_RS13265	COG2801	Transposase and inactivated derivatives
YPZ3_RS13295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPZ3_RS13310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPZ3_RS13325	COG1169	isochorismate synthase
YPZ3_RS13335	COG4575	ribosome binding
YPZ3_RS13350	COG0129	dihydroxy-acid dehydratase activity
YPZ3_RS13365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPZ3_RS13375	COG1609	Transcriptional regulator
YPZ3_RS13380	COG1649	PFAM Uncharacterised BCR, COG1649
YPZ3_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS13390	COG3265	gluconokinase activity
YPZ3_RS13395	COG2731	YhcH YjgK YiaL family protein
YPZ3_RS13410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPZ3_RS13415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPZ3_RS13425	COG0839	Belongs to the complex I subunit 6 family
YPZ3_RS13440	COG1034	ATP synthesis coupled electron transport
YPZ3_RS13460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPZ3_RS13470	COG0583	DNA-binding transcription factor activity
YPZ3_RS13480	COG0436	Aminotransferase
YPZ3_RS13495	COG0490	domain, Protein
YPZ3_RS13495	COG0471	metal ion transport
YPZ3_RS13500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPZ3_RS13525	COG0280	phosphate acetyltransferase
YPZ3_RS13525	COG0857	belongs to the CobB CobQ family
YPZ3_RS13530	COG1609	Transcriptional regulator
YPZ3_RS13545	COG3328	transposase activity
YPZ3_RS13550	COG4953	penicillin-binding protein 1C
YPZ3_RS13555	COG2373	Large extracellular alpha-helical protein
YPZ3_RS13575	COG3962	Belongs to the TPP enzyme family
YPZ3_RS13590	COG1129	ABC transporter
YPZ3_RS13595	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS13600	COG0673	inositol 2-dehydrogenase activity
YPZ3_RS13605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_RS13615	COG3718	enzyme involved in inositol metabolism
YPZ3_RS13625	COG5265	(ABC) transporter
YPZ3_RS13650	COG2197	response regulator
YPZ3_RS13665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPZ3_RS13675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPZ3_RS13695	COG1686	Belongs to the peptidase S11 family
YPZ3_RS13705	COG0772	Belongs to the SEDS family
YPZ3_RS13710	COG0768	penicillin binding
YPZ3_RS13720	COG0799	negative regulation of ribosome biogenesis
YPZ3_RS13730	COG1466	dna polymerase III delta subunit
YPZ3_RS13745	COG2888	peptidyl-tyrosine sulfation
YPZ3_RS13750	COG1126	abc transporter atp-binding protein
YPZ3_RS13755	COG0765	amino acid transport
YPZ3_RS13760	COG0765	amino acid transport
YPZ3_RS13770	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPZ3_RS13775	COG4535	Mg2 and Co2 transporter CorC
YPZ3_RS13785	COG1702	phosphate starvation-inducible protein PhoH
YPZ3_RS13790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YPZ3_RS13795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPZ3_RS13830	COG0367	asparagine synthase
YPZ3_RS13835	COG0647	UMP catabolic process
YPZ3_RS13840	COG1940	carbohydrate kinase activity
YPZ3_RS13840	COG1846	Transcriptional regulator
YPZ3_RS13845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPZ3_RS13880	COG0735	belongs to the Fur family
YPZ3_RS13900	COG0596	Alpha beta hydrolase
YPZ3_RS13910	COG0582	viral genome integration into host DNA
YPZ3_RS13915	COG2963	transposase activity
YPZ3_RS13920	COG0582	viral genome integration into host DNA
YPZ3_RS13940	COG2113	Glycine betaine
YPZ3_RS13945	COG4176	ABC-type proline glycine betaine transport system permease component
YPZ3_RS13950	COG4175	Glycine betaine
YPZ3_RS13955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPZ3_RS13995	COG1278	Cold shock
YPZ3_RS14000	COG0747	negative chemotaxis
YPZ3_RS14010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPZ3_RS14015	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPZ3_RS14020	COG1124	(ABC) transporter
YPZ3_RS14025	COG0831	urea catabolic process
YPZ3_RS14050	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPZ3_RS14060	COG4413	Urea transporter
YPZ3_RS14065	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPZ3_RS14080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPZ3_RS14090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPZ3_RS14100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPZ3_RS14105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPZ3_RS14110	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPZ3_RS14115	COG1917	Cupin 2, conserved barrel domain protein
YPZ3_RS14115	COG2169	Transcriptional regulator
YPZ3_RS14135	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPZ3_RS14140	COG0033	Phosphoglucomutase
YPZ3_RS14160	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS14165	COG2205	protein histidine kinase activity
YPZ3_RS14200	COG3272	Protein of unknown function (DUF1722)
YPZ3_RS14210	COG5212	phosphodiesterase
YPZ3_RS14215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPZ3_RS14225	COG1984	allophanate hydrolase subunit 2
YPZ3_RS14275	COG0513	Belongs to the DEAD box helicase family
YPZ3_RS14285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPZ3_RS14300	COG3026	antisigma factor binding
YPZ3_RS14305	COG3086	response to oxidative stress
YPZ3_RS14350	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YPZ3_RS14370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_RS14375	COG1737	Transcriptional regulator
YPZ3_RS14425	COG2205	protein histidine kinase activity
YPZ3_RS14430	COG3170	Tfp pilus assembly protein FimV
YPZ3_RS14435	COG2204	response regulator
YPZ3_RS14440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPZ3_RS14440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPZ3_RS14445	COG0347	Belongs to the P(II) protein family
YPZ3_RS14450	COG2188	Transcriptional regulator
YPZ3_RS14455	COG2188	Transcriptional regulator
YPZ3_RS14460	COG1017	nitric oxide dioxygenase activity
YPZ3_RS14460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_RS14480	COG2814	Major facilitator Superfamily
YPZ3_RS14485	COG3711	transcriptional antiterminator
YPZ3_RS14490	COG3683	transport system, periplasmic component
YPZ3_RS14495	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPZ3_RS14520	COG1104	cysteine desulfurase activity
YPZ3_RS14525	COG0822	iron-sulfur transferase activity
YPZ3_RS14540	COG0443	Heat shock 70 kDa protein
YPZ3_RS14545	COG0633	Ferredoxin
YPZ3_RS14550	COG2975	iron-sulfur cluster assembly
YPZ3_RS14570	COG3468	outer membrane autotransporter barrel domain protein
YPZ3_RS14575	COG3468	outer membrane autotransporter barrel domain protein
YPZ3_RS14620	COG2976	Protein conserved in bacteria
YPZ3_RS14625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPZ3_RS14640	COG1645	bacterial-type flagellum-dependent swarming motility
YPZ3_RS14650	COG0517	IMP dehydrogenase activity
YPZ3_RS14650	COG0516	GMP reductase activity
YPZ3_RS14705	COG3328	transposase activity
YPZ3_RS14720	COG0351	phosphomethylpyrimidine kinase
YPZ3_RS14740	COG0826	peptidase U32
YPZ3_RS14745	COG3422	double-strand break repair
YPZ3_RS14750	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS14755	COG2205	protein histidine kinase activity
YPZ3_RS14760	COG2205	protein histidine kinase activity
YPZ3_RS14785	COG3842	ATPase activity
YPZ3_RS14795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPZ3_RS14805	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPZ3_RS14810	COG1177	transmembrane transport
YPZ3_RS14815	COG0443	Heat shock 70 kDa protein
YPZ3_RS14820	COG2239	Acts as a magnesium transporter
YPZ3_RS14835	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPZ3_RS14845	COG0581	inorganic phosphate transmembrane transporter activity
YPZ3_RS14865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPZ3_RS14870	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPZ3_RS14890	COG2501	S4 domain
YPZ3_RS14940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPZ3_RS14945	COG4589	Belongs to the CDS family
YPZ3_RS14955	COG2267	carboxylic ester hydrolase activity
YPZ3_RS14960	COG2453	phosphatase
YPZ3_RS14960	COG0671	phosphoesterase, PA-phosphatase related
YPZ3_RS14990	COG0667	Aldo Keto reductase
YPZ3_RS14995	COG0656	L-ascorbic acid biosynthetic process
YPZ3_RS15015	COG1472	Belongs to the glycosyl hydrolase 3 family
YPZ3_RS15030	COG3328	transposase activity
YPZ3_RS15035	COG2850	peptidyl-arginine hydroxylation
YPZ3_RS15080	COG3423	Transcriptional regulator
YPZ3_RS15085	COG4953	penicillin-binding protein 1C
YPZ3_RS15090	COG3328	transposase activity
YPZ3_RS15100	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPZ3_RS15105	COG0622	Phosphoesterase
YPZ3_RS15115	COG1090	epimerase
YPZ3_RS15120	COG4598	ABC transporter
YPZ3_RS15125	COG4160	amino acid transport
YPZ3_RS15130	COG4215	(ABC) transporter
YPZ3_RS15135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_RS15145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPZ3_RS15150	COG1286	toxin biosynthetic process
YPZ3_RS15155	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPZ3_RS15160	COG0285	dihydrofolate synthase activity
YPZ3_RS15170	COG0586	Pfam SNARE associated Golgi protein
YPZ3_RS15180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPZ3_RS15200	COG0697	spore germination
YPZ3_RS15215	COG1794	racemase activity, acting on amino acids and derivatives
YPZ3_RS15220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPZ3_RS15235	COG3101	peptidyl-lysine hydroxylation
YPZ3_RS15240	COG0730	response to heat
YPZ3_RS15255	COG2890	protein-(glutamine-N5) methyltransferase activity
YPZ3_RS15265	COG2062	phosphohistidine phosphatase, SixA
YPZ3_RS15280	COG3691	Protein conserved in bacteria
YPZ3_RS15295	COG3088	subunit of a heme lyase
YPZ3_RS15295	COG4235	cytochrome complex assembly
YPZ3_RS15300	COG3088	subunit of a heme lyase
YPZ3_RS15300	COG4235	cytochrome complex assembly
YPZ3_RS15305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPZ3_RS15310	COG1138	Cytochrome C-type biogenesis protein
YPZ3_RS15320	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPZ3_RS15325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPZ3_RS15330	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPZ3_RS15350	COG1704	LemA family
YPZ3_RS15360	COG2824	Alkylphosphonate utilization operon protein PhnA
YPZ3_RS15450	COG3188	usher protein
YPZ3_RS15455	COG3328	transposase activity
YPZ3_RS15460	COG3188	usher protein
YPZ3_RS15465	COG3121	Chaperone
YPZ3_RS15525	COG2951	lytic endotransglycosylase activity
YPZ3_RS15560	COG0243	molybdopterin cofactor binding
YPZ3_RS15565	COG0437	4 iron, 4 sulfur cluster binding
YPZ3_RS15570	COG3302	dmso reductase anchor subunit
YPZ3_RS15575	COG3381	protein complex oligomerization
YPZ3_RS15605	COG3038	cytochrome b561
YPZ3_RS15610	COG0436	Aminotransferase
YPZ3_RS15635	COG0667	Aldo Keto reductase
YPZ3_RS15650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPZ3_RS15705	COG3530	Putative quorum-sensing-regulated virulence factor
YPZ3_RS15720	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPZ3_RS15730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_RS15755	COG2205	protein histidine kinase activity
YPZ3_RS15760	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS15765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_RS15780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPZ3_RS15800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPZ3_RS15810	COG3850	Histidine kinase
YPZ3_RS15810	COG5002	protein histidine kinase activity
YPZ3_RS15815	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS15830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YPZ3_RS15835	COG4208	sulfate ABC transporter
YPZ3_RS15840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPZ3_RS15845	COG4150	thiosulfate binding
YPZ3_RS15855	COG1737	Transcriptional regulator
YPZ3_RS15865	COG2731	YhcH YjgK YiaL family protein
YPZ3_RS15875	COG4886	Leucine-rich repeat (LRR) protein
YPZ3_RS15885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPZ3_RS15890	COG2837	iron assimilation
YPZ3_RS15900	COG3111	PFAM Bacterial OB fold (BOF) protein
YPZ3_RS15945	COG3005	denitrification pathway
YPZ3_RS15950	COG3043	anaerobic respiration
YPZ3_RS15960	COG3062	negative regulation of establishment of protein localization
YPZ3_RS15965	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_RS15965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPZ3_RS15970	COG2197	response regulator
YPZ3_RS15980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPZ3_RS15990	COG1988	membrane-bound metal-dependent
YPZ3_RS15995	COG0641	radical SAM
YPZ3_RS16000	COG3119	arylsulfatase activity
YPZ3_RS16005	COG3842	ATPase activity
YPZ3_RS16010	COG1175	transmembrane transport
YPZ3_RS16025	COG1393	Belongs to the ArsC family
YPZ3_RS16035	COG1876	peptidase activity
YPZ3_RS16055	COG2321	neutral zinc metallopeptidase
YPZ3_RS16075	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPZ3_RS16085	COG2716	regulation of RNA biosynthetic process
YPZ3_RS16090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPZ3_RS16110	COG0628	permease
YPZ3_RS16115	COG4783	chaperone-mediated protein folding
YPZ3_RS16120	COG1393	Belongs to the ArsC family
YPZ3_RS16145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPZ3_RS16155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPZ3_RS16160	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPZ3_RS16165	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPZ3_RS16170	COG4181	ATPase activity
YPZ3_RS16175	COG2755	lipolytic protein G-D-S-L family
YPZ3_RS16180	COG0300	oxidoreductase activity
YPZ3_RS16185	COG3118	belongs to the thioredoxin family
YPZ3_RS16190	COG0330	HflC and HflK could
YPZ3_RS16195	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPZ3_RS16200	COG0789	Transcriptional regulator
YPZ3_RS16205	COG2217	Heavy metal translocating P-type atpase
YPZ3_RS16210	COG3735	TraB family
YPZ3_RS16215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPZ3_RS16230	COG0737	Belongs to the 5'-nucleotidase family
YPZ3_RS16235	COG0737	Belongs to the 5'-nucleotidase family
YPZ3_RS16240	COG0737	Belongs to the 5'-nucleotidase family
YPZ3_RS16245	COG2223	nitrite transmembrane transporter activity
YPZ3_RS16250	COG4651	solute:proton antiporter activity
YPZ3_RS16250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPZ3_RS16255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_RS16260	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPZ3_RS16280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_RS16320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPZ3_RS16345	COG0543	2 iron, 2 sulfur cluster binding
YPZ3_RS16345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPZ3_RS16375	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPZ3_RS16400	COG3264	Mechanosensitive ion channel
YPZ3_RS16400	COG1196	nuclear chromosome segregation
YPZ3_RS16405	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPZ3_RS16410	COG1309	transcriptional regulator
YPZ3_RS16415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPZ3_RS16420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPZ3_RS16430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPZ3_RS16450	COG3695	enzyme binding
YPZ3_RS16455	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPZ3_RS16460	COG1946	Acyl-CoA thioesterase
YPZ3_RS16465	COG0004	ammonium transporteR
YPZ3_RS16470	COG0347	Belongs to the P(II) protein family
YPZ3_RS16475	COG1132	(ABC) transporter
YPZ3_RS16480	COG1132	(ABC) transporter
YPZ3_RS16485	COG1522	sequence-specific DNA binding
YPZ3_RS16500	COG4533	DNA binding
YPZ3_RS16510	COG0824	Thioesterase
YPZ3_RS16515	COG1555	photosystem II stabilization
YPZ3_RS16520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPZ3_RS16525	COG0776	regulation of translation
YPZ3_RS16530	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPZ3_RS16555	COG0271	Belongs to the BolA IbaG family
YPZ3_RS16560	COG3056	Lipoprotein
YPZ3_RS16565	COG2223	nitrite transmembrane transporter activity
YPZ3_RS16575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPZ3_RS16580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPZ3_RS16585	COG1845	cytochrome c oxidase, subunit III
YPZ3_RS16590	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPZ3_RS16600	COG2814	Major facilitator Superfamily
YPZ3_RS16610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPZ3_RS16615	COG0693	protein deglycase activity
YPZ3_RS16635	COG0142	geranyltranstransferase activity
YPZ3_RS16655	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPZ3_RS16660	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPZ3_RS16675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPZ3_RS16675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPZ3_RS16700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPZ3_RS16705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPZ3_RS16710	COG1862	Preprotein translocase
YPZ3_RS16730	COG0450	alkyl hydroperoxide reductase
YPZ3_RS16760	COG0366	Alpha amylase catalytic
YPZ3_RS16780	COG5002	protein histidine kinase activity
YPZ3_RS16785	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS16795	COG0420	3'-5' exonuclease activity
YPZ3_RS16800	COG0419	ATPase involved in DNA repair
YPZ3_RS16805	COG1940	carbohydrate kinase activity
YPZ3_RS16840	COG2226	methyltransferase
YPZ3_RS16900	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPZ3_RS16920	COG1477	protein flavinylation
YPZ3_RS16940	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPZ3_RS16945	COG1805	sodium ion transport
YPZ3_RS16955	COG3034	peptidoglycan biosynthetic process
YPZ3_RS16960	COG0121	glutamine amidotransferase
YPZ3_RS16970	COG1960	acyl-CoA dehydrogenase activity
YPZ3_RS16980	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPZ3_RS17000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPZ3_RS17015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPZ3_RS17025	COG0765	amino acid transport
YPZ3_RS17065	COG2814	Major facilitator Superfamily
YPZ3_RS17070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPZ3_RS17080	COG1846	Transcriptional regulator
YPZ3_RS17085	COG1566	PFAM secretion protein HlyD family protein
YPZ3_RS17090	COG2814	Major facilitator Superfamily
YPZ3_RS17095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPZ3_RS17100	COG3118	belongs to the thioredoxin family
YPZ3_RS17105	COG3148	PFAM DTW domain containing protein
YPZ3_RS17110	COG1042	CoA-binding domain protein
YPZ3_RS17110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPZ3_RS17110	COG0045	succinate-CoA ligase (ADP-forming) activity
YPZ3_RS17115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPZ3_RS17120	COG5544	Lipoprotein
YPZ3_RS17155	COG0542	response to heat
YPZ3_RS17165	COG0564	pseudouridine synthase activity
YPZ3_RS17170	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPZ3_RS17175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPZ3_RS17190	COG1605	Chorismate mutase
YPZ3_RS17190	COG0077	Prephenate dehydratase
YPZ3_RS17205	COG0077	Prephenate dehydratase
YPZ3_RS17205	COG1605	Chorismate mutase
YPZ3_RS17210	COG0287	Prephenate dehydrogenase
YPZ3_RS17210	COG1605	Chorismate mutase
YPZ3_RS17215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPZ3_RS17220	COG3279	Response regulator of the LytR AlgR family
YPZ3_RS17225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPZ3_RS17230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPZ3_RS17235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPZ3_RS17240	COG3137	Salt-induced outer membrane protein
YPZ3_RS17275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPZ3_RS17280	COG4137	Cytochrome C assembly protein
YPZ3_RS17285	COG4536	flavin adenine dinucleotide binding
YPZ3_RS17305	COG2918	glutathione biosynthetic process
YPZ3_RS17310	COG1238	metal cluster binding
YPZ3_RS17315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPZ3_RS17340	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPZ3_RS17380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPZ3_RS17385	COG3958	Transketolase
YPZ3_RS17390	COG3959	Transketolase, thiamine diphosphate binding domain
YPZ3_RS17395	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS17400	COG1129	ABC transporter
YPZ3_RS17410	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_RS17420	COG3783	Cytochrome b(562)
YPZ3_RS17425	COG3038	cytochrome b561
YPZ3_RS17430	COG3381	protein complex oligomerization
YPZ3_RS17435	COG3302	dmso reductase anchor subunit
YPZ3_RS17440	COG0437	4 iron, 4 sulfur cluster binding
YPZ3_RS17445	COG0243	molybdopterin cofactor binding
YPZ3_RS17450	COG0235	Class ii aldolase
YPZ3_RS17455	COG1349	DNA-binding transcription factor activity
YPZ3_RS17470	COG1129	ABC transporter
YPZ3_RS17475	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS17480	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS17485	COG3623	hexulose-6-phosphate isomerase
YPZ3_RS17490	COG1070	Carbohydrate kinase
YPZ3_RS17495	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPZ3_RS17495	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPZ3_RS17505	COG0024	Methionine aminopeptidase
YPZ3_RS17525	COG4771	TonB-dependent receptor
YPZ3_RS17535	COG1858	cytochrome C peroxidase
YPZ3_RS17540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_RS17560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPZ3_RS17575	COG2376	Dihydroxyacetone kinase
YPZ3_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
YPZ3_RS17585	COG1063	alcohol dehydrogenase
YPZ3_RS17590	COG0698	ribose 5-phosphate isomerase
YPZ3_RS17605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPZ3_RS17610	COG1388	LysM domain
YPZ3_RS17610	COG4942	peptidase
YPZ3_RS17650	COG0529	Catalyzes the synthesis of activated sulfate
YPZ3_RS17700	COG0720	synthase
YPZ3_RS17705	COG0602	queuosine metabolic process
YPZ3_RS17725	COG3956	TIGRFAM MazG family protein
YPZ3_RS17735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPZ3_RS17740	COG2205	protein histidine kinase activity
YPZ3_RS17740	COG4999	Histidine kinase
YPZ3_RS17740	COG3850	Histidine kinase
YPZ3_RS17740	COG3437	response regulator, receiver
YPZ3_RS17745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPZ3_RS17765	COG2860	membrane
YPZ3_RS17785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPZ3_RS17790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPZ3_RS17800	COG1120	ATPase activity
YPZ3_RS17805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPZ3_RS17810	COG1643	Atp-dependent helicase
YPZ3_RS17815	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPZ3_RS17830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YPZ3_RS17835	COG0617	tRNA 3'-terminal CCA addition
YPZ3_RS17840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPZ3_RS17865	COG0842	Transport permease protein
YPZ3_RS17870	COG1131	(ABC) transporter
YPZ3_RS17875	COG0288	reversible hydration of carbon dioxide
YPZ3_RS17880	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPZ3_RS17885	COG2132	Multicopper oxidase
YPZ3_RS17905	COG0697	spore germination
YPZ3_RS17915	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPZ3_RS17930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPZ3_RS17935	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPZ3_RS17940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPZ3_RS17945	COG2186	Transcriptional regulator
YPZ3_RS17950	COG1113	amino acid transport
YPZ3_RS17955	COG3725	Membrane protein required for beta-lactamase induction
YPZ3_RS17960	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPZ3_RS17970	COG4969	Belongs to the N-Me-Phe pilin family
YPZ3_RS17975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPZ3_RS17980	COG1459	type II secretion system
YPZ3_RS18035	COG0582	viral genome integration into host DNA
YPZ3_RS18045	COG0795	lipopolysaccharide-transporting ATPase activity
YPZ3_RS18050	COG0795	lipopolysaccharide-transporting ATPase activity
YPZ3_RS18060	COG2927	DNA polymerase III (CHI subunit)
YPZ3_RS18065	COG0525	valine-tRNA ligase activity
YPZ3_RS18075	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPZ3_RS18085	COG2731	YhcH YjgK YiaL family protein
YPZ3_RS18095	COG0601	transmembrane transport
YPZ3_RS18100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPZ3_RS18105	COG0444	Belongs to the ABC transporter superfamily
YPZ3_RS18110	COG4608	Belongs to the ABC transporter superfamily
YPZ3_RS18125	COG2188	Transcriptional regulator
YPZ3_RS18130	COG3624	Phosphonate C-P lyase system protein PhnG
YPZ3_RS18135	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPZ3_RS18140	COG3626	phosphonate metabolism
YPZ3_RS18145	COG3627	carbon phosphorus lyase activity
YPZ3_RS18150	COG4107	phosphonate C-P lyase system protein PhnK
YPZ3_RS18155	COG4778	phosphonate C-P lyase system protein PhnL
YPZ3_RS18160	COG3454	Phosphonate metabolism
YPZ3_RS18165	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPZ3_RS18170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPZ3_RS18175	COG0702	epimerase
YPZ3_RS18190	COG3842	ATPase activity
YPZ3_RS18195	COG0395	ABC-type sugar transport system, permease component
YPZ3_RS18200	COG1175	transmembrane transport
YPZ3_RS18205	COG1653	transport
YPZ3_RS18225	COG3153	acetyltransferase
YPZ3_RS18230	COG3154	lipid carrier protein
YPZ3_RS18240	COG0826	peptidase U32
YPZ3_RS18245	COG0826	peptidase U32
YPZ3_RS18255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPZ3_RS18265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPZ3_RS18285	COG0513	Belongs to the DEAD box helicase family
YPZ3_RS18300	COG2801	Transposase and inactivated derivatives
YPZ3_RS18375	COG3501	Rhs element vgr protein
YPZ3_RS18420	COG3501	Rhs element vgr protein
YPZ3_RS18430	COG3209	COG3209 Rhs family protein
YPZ3_RS18445	COG0673	inositol 2-dehydrogenase activity
YPZ3_RS18450	COG1917	Cupin 2, conserved barrel domain protein
YPZ3_RS18450	COG2207	Transcriptional regulator
YPZ3_RS18455	COG1869	D-ribose catabolic process
YPZ3_RS18460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPZ3_RS18465	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPZ3_RS18470	COG0431	NADPH-dependent FMN reductase
YPZ3_RS18475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPZ3_RS18485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPZ3_RS18495	COG3077	Addiction module antitoxin, RelB DinJ family
YPZ3_RS18500	COG2252	PERMEase
YPZ3_RS18505	COG0025	NhaP-type Na H and K H
YPZ3_RS18515	COG1560	Kdo2-lipid A biosynthetic process
YPZ3_RS18525	COG1129	ABC transporter
YPZ3_RS18530	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS18540	COG1069	ribulokinase activity
YPZ3_RS18550	COG0625	glutathione transferase activity
YPZ3_RS18575	COG1278	Cold shock
YPZ3_RS18580	COG1278	Cold shock
YPZ3_RS18590	COG3133	Outer membrane lipoprotein
YPZ3_RS18595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPZ3_RS18605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPZ3_RS18625	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPZ3_RS18630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPZ3_RS18640	COG4145	pantothenate transmembrane transporter activity
YPZ3_RS18645	COG3924	membrane
YPZ3_RS18650	COG0439	Biotin carboxylase
YPZ3_RS18655	COG0511	ligase activity, forming carbon-carbon bonds
YPZ3_RS18670	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YPZ3_RS18675	COG0604	alcohol dehydrogenase
YPZ3_RS18680	COG2200	EAL domain
YPZ3_RS18680	COG2199	diguanylate cyclase activity
YPZ3_RS18685	COG1077	Cell shape determining protein MreB Mrl
YPZ3_RS18690	COG1792	Involved in formation and maintenance of cell shape
YPZ3_RS18695	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPZ3_RS18700	COG0424	maF-like protein
YPZ3_RS18705	COG1530	ribonuclease E activity
YPZ3_RS18710	COG3164	Protein of unknown function
YPZ3_RS18715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPZ3_RS18720	COG0312	modulator of DNA gyrase
YPZ3_RS18780	COG0583	DNA-binding transcription factor activity
YPZ3_RS18800	COG1012	belongs to the aldehyde dehydrogenase family
YPZ3_RS18815	COG2732	(Barnase) inhibitor
YPZ3_RS18825	COG0312	modulator of DNA gyrase
YPZ3_RS18835	COG3783	Cytochrome b(562)
YPZ3_RS18840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPZ3_RS18845	COG0366	Alpha amylase catalytic
YPZ3_RS18850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPZ3_RS18850	COG1263	PTS System
YPZ3_RS18855	COG1609	Transcriptional regulator
YPZ3_RS18880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_RS18900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPZ3_RS18905	COG1137	ATPase activity
YPZ3_RS18910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPZ3_RS18915	COG3117	lipopolysaccharide transmembrane transporter activity
YPZ3_RS18920	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPZ3_RS18925	COG0517	IMP dehydrogenase activity
YPZ3_RS18925	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPZ3_RS18930	COG0530	calcium, potassium:sodium antiporter activity
YPZ3_RS18935	COG1127	ABC transporter
YPZ3_RS18940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPZ3_RS18945	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPZ3_RS18950	COG2854	intermembrane phospholipid transfer
YPZ3_RS18955	COG3113	response to antibiotic
YPZ3_RS18960	COG5007	Belongs to the BolA IbaG family
YPZ3_RS18970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPZ3_RS18980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPZ3_RS18985	COG3105	Protein conserved in bacteria
YPZ3_RS18990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPZ3_RS19010	COG0625	glutathione transferase activity
YPZ3_RS19015	COG2969	positive regulation of protein catabolic process
YPZ3_RS19025	COG0493	'glutamate synthase
YPZ3_RS19030	COG0070	glutamate synthase
YPZ3_RS19030	COG0069	glutamate synthase activity
YPZ3_RS19030	COG0067	glutamate synthase
YPZ3_RS19035	COG1242	4 iron, 4 sulfur cluster binding
YPZ3_RS19045	COG5002	protein histidine kinase activity
YPZ3_RS19045	COG2198	Histidine kinase
YPZ3_RS19045	COG0784	Response regulator, receiver
YPZ3_RS19055	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPZ3_RS19065	COG2823	Periplasmic or secreted lipoprotein
YPZ3_RS19085	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPZ3_RS19090	COG1741	Belongs to the pirin family
YPZ3_RS19095	COG0583	DNA-binding transcription factor activity
YPZ3_RS19100	COG0435	Glutathione S-transferase
YPZ3_RS19115	COG1073	alpha beta
YPZ3_RS19125	COG0360	Binds together with S18 to 16S ribosomal RNA
YPZ3_RS19135	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPZ3_RS19160	COG3061	Opacity-associated protein A
YPZ3_RS19165	COG0545	Peptidyl-prolyl cis-trans isomerase
YPZ3_RS19175	COG0737	Belongs to the 5'-nucleotidase family
YPZ3_RS19185	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPZ3_RS19195	COG1253	flavin adenine dinucleotide binding
YPZ3_RS19205	COG0729	surface antigen
YPZ3_RS19210	COG2911	Protein conserved in bacteria
YPZ3_RS19215	COG2105	PFAM AIG2 family protein
YPZ3_RS19220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPZ3_RS19225	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YPZ3_RS19230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPZ3_RS19255	COG3423	Transcriptional regulator
YPZ3_RS19265	COG0142	geranyltranstransferase activity
YPZ3_RS19280	COG0697	spore germination
YPZ3_RS19290	COG0642	Histidine kinase
YPZ3_RS19295	COG0745	RESPONSE REGULATOR receiver
YPZ3_RS19300	COG2027	D-alanyl-D-alanine carboxypeptidase
YPZ3_RS19310	COG1534	Rna-binding protein
YPZ3_RS19325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPZ3_RS19335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPZ3_RS19355	COG0195	Participates in both transcription termination and antitermination
YPZ3_RS19385	COG2801	Transposase and inactivated derivatives
YPZ3_RS19445	COG1175	transmembrane transport
YPZ3_RS19450	COG3833	ABC-type maltose transport systems, permease component
YPZ3_RS19465	COG0527	aspartate kinase activity
YPZ3_RS19490	COG1414	Transcriptional regulator
YPZ3_RS19495	COG1414	Transcriptional regulator
YPZ3_RS19505	COG2224	Isocitrate lyase
YPZ3_RS19510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPZ3_RS19570	COG0151	Belongs to the GarS family
YPZ3_RS19630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPZ3_RS19695	COG0250	Participates in transcription elongation, termination and antitermination
YPZ3_RS19755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YPZ3_RS19790	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPZ3_RS19795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPZ3_RS19800	COG1739	Uncharacterized protein family UPF0029
YPZ3_RS19810	COG1739	Uncharacterized protein family UPF0029
YPZ3_RS19835	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YPZ3_RS19870	COG0805	protein transport
YPZ3_RS19880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPZ3_RS19900	COG1322	Protein conserved in bacteria
YPZ3_RS19905	COG0586	Pfam SNARE associated Golgi protein
YPZ3_RS19910	COG1966	Carbon starvation protein
YPZ3_RS19925	COG0412	Dienelactone hydrolase
YPZ3_RS19935	COG0583	DNA-binding transcription factor activity
YPZ3_RS19940	COG0697	spore germination
YPZ3_RS19945	COG0679	Auxin Efflux Carrier
YPZ3_RS19950	COG0584	glycerophosphoryl diester phosphodiesterase
YPZ3_RS20010	COG0410	ABC transporter
YPZ3_RS20020	COG4177	L-phenylalanine transmembrane transporter activity
YPZ3_RS20030	COG0683	leucine binding
YPZ3_RS20055	COG2177	Part of the ABC transporter FtsEX involved in
YPZ3_RS20060	COG2884	Cell division ATP-binding protein ftsE
YPZ3_RS20065	COG0552	protein localization to endoplasmic reticulum
YPZ3_RS20065	COG0552	protein localization to endoplasmic reticulum
YPZ3_RS20075	COG0742	ribosomal rna small subunit methyltransferase
YPZ3_RS20080	COG3776	membrane
YPZ3_RS20095	COG3714	YhhN family
YPZ3_RS20110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPZ3_RS20120	COG0247	lactate metabolic process
YPZ3_RS20130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPZ3_RS20140	COG0584	glycerophosphoryl diester phosphodiesterase
YPZ3_RS20150	COG0561	phosphatase activity
YPZ3_RS20155	COG2267	carboxylic ester hydrolase activity
YPZ3_RS20160	COG1280	lysine exporter protein (LysE YggA)
YPZ3_RS20165	COG1280	lysine exporter protein (LysE YggA)
YPZ3_RS20170	COG0514	ATP-dependent DNA helicase (RecQ)
YPZ3_RS20175	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPZ3_RS20180	COG2050	protein possibly involved in aromatic compounds catabolism
YPZ3_RS20195	COG5564	TIM-barrel signal transduction protein
YPZ3_RS20200	COG5441	Belongs to the UPF0261 family
YPZ3_RS20210	COG0210	DNA helicase
YPZ3_RS20215	COG1011	Hydrolase
YPZ3_RS20220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPZ3_RS20225	COG3159	Protein conserved in bacteria
YPZ3_RS20245	COG3072	Adenylate cyclase
YPZ3_RS20255	COG1587	Uroporphyrinogen-III synthase
YPZ3_RS20260	COG2959	enzyme of heme biosynthesis
YPZ3_RS20265	COG3071	HemY protein
YPZ3_RS20295	COG1113	amino acid transport
YPZ3_RS20315	COG2244	polysaccharide biosynthetic process
YPZ3_RS20320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPZ3_RS20325	COG0456	acetyltransferase
YPZ3_RS20330	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPZ3_RS20335	COG1088	dTDP-glucose 4,6-dehydratase activity
YPZ3_RS20340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPZ3_RS20345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPZ3_RS20350	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPZ3_RS20355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPZ3_RS20360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPZ3_RS20365	COG3118	belongs to the thioredoxin family
YPZ3_RS20395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPZ3_RS20405	COG3328	transposase activity
YPZ3_RS20420	COG3121	Chaperone
YPZ3_RS20435	COG3121	Chaperone
YPZ3_RS20475	COG0583	DNA-binding transcription factor activity
YPZ3_RS20515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPZ3_RS20520	COG3978	acetolactate synthase activity
YPZ3_RS20535	COG3085	chromosome segregation
YPZ3_RS20545	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS20550	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPZ3_RS20555	COG1129	ABC transporter
YPZ3_RS20560	COG1879	ABC-type sugar transport system periplasmic component
YPZ3_RS20640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPZ3_RS20640	COG0678	peroxiredoxin activity
YPZ3_RS20645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPZ3_RS20670	COG1629	transport
YPZ3_RS20690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YPZ3_RS20710	COG2801	Transposase and inactivated derivatives
YPZ3_RS20745	COG3276	selenocysteine insertion sequence binding
YPZ3_RS20760	COG2864	formate dehydrogenase
YPZ3_RS20765	COG0437	4 iron, 4 sulfur cluster binding
YPZ3_RS20770	COG3383	formate dehydrogenase (NAD+) activity
YPZ3_RS20770	COG0243	molybdopterin cofactor binding
YPZ3_RS20775	COG0243	molybdopterin cofactor binding
YPZ3_RS20775	COG3383	formate dehydrogenase (NAD+) activity
YPZ3_RS20785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPZ3_RS20810	COG3722	fumarate hydratase activity
YPZ3_RS20820	COG2213	PTS system mannitol-specific
YPZ3_RS20820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPZ3_RS20840	COG2818	Glycosylase
YPZ3_RS20850	COG2885	chlorophyll binding
YPZ3_RS20865	COG0366	Alpha amylase catalytic
YPZ3_RS20875	COG3977	Valine--pyruvate aminotransferase
YPZ3_RS20895	COG5645	(Lipo)protein
YPZ3_RS20900	COG0823	Involved in the tonB-independent uptake of proteins
YPZ3_RS20905	COG0823	Involved in the tonB-independent uptake of proteins
YPZ3_RS20910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPZ3_RS20915	COG2423	ornithine cyclodeaminase activity
YPZ3_RS20925	COG2801	Transposase and inactivated derivatives
YPZ3_RS20930	COG0561	phosphatase activity
YPZ3_RS20935	COG0187	DNA topoisomerase II activity
YPZ3_RS20950	COG0592	DNA-directed DNA polymerase activity
YPZ3_RS20960	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPZ3_RS20970	COG0706	membrane insertase activity
YPZ3_RS20995	COG2252	PERMEase
YPZ3_RS21000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPZ3_RS21005	COG0765	amino acid transport
YPZ3_RS21010	COG0765	amino acid transport
YPZ3_RS21015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPZ3_RS21025	COG0704	Plays a role in the regulation of phosphate uptake
YPZ3_RS21035	COG0581	inorganic phosphate transmembrane transporter activity
YPZ3_RS21040	COG0573	inorganic phosphate transmembrane transporter activity
YPZ3_RS21045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPZ3_RS21100	COG3312	ion transport
YPZ3_RS21190	COG0477	Major facilitator Superfamily
YPZ3_RS21435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPZ3_RS21550	COG0859	PFAM glycosyl transferase family 9
YPZ3_RS21830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPZ3_RS21940	COG0859	PFAM glycosyl transferase family 9
YPZ3_RS22025	COG2205	protein histidine kinase activity