locus-tag	class	description
YP_RS00005	COG0716	FMN binding
YP_RS00010	COG1522	sequence-specific DNA binding
YP_RS00040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YP_RS00050	COG0477	Major facilitator Superfamily
YP_RS00055	COG2186	Transcriptional regulator
YP_RS00085	COG3328	transposase activity
YP_RS00090	COG1763	Mo-molybdopterin cofactor biosynthetic process
YP_RS00100	COG3084	Protein conserved in bacteria
YP_RS00105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YP_RS00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YP_RS00115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YP_RS00115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YP_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YP_RS00150	COG3852	Histidine kinase
YP_RS00155	COG0174	glutamine synthetase
YP_RS00170	COG1011	Hydrolase
YP_RS00195	COG0456	acetyltransferase
YP_RS00200	COG2982	Protein involved in outer membrane biogenesis
YP_RS00205	COG2233	PERMEase
YP_RS00210	COG0786	glutamate:sodium symporter activity
YP_RS00215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YP_RS00220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YP_RS00225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YP_RS00245	COG2860	membrane
YP_RS00250	COG1561	YicC-like family, N-terminal region
YP_RS00275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YP_RS00310	COG1519	Transferase
YP_RS00315	COG0859	PFAM glycosyl transferase family 9
YP_RS00320	COG0859	PFAM glycosyl transferase family 9
YP_RS00330	COG0156	8-amino-7-oxononanoate synthase activity
YP_RS00345	COG4942	peptidase
YP_RS00355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YP_RS00360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YP_RS00380	COG1045	serine acetyltransferase
YP_RS00385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YP_RS00390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YP_RS00390	COG2169	Transcriptional regulator
YP_RS00395	COG2205	protein histidine kinase activity
YP_RS00400	COG0745	RESPONSE REGULATOR receiver
YP_RS00405	COG3678	ATP-independent chaperone mediated protein folding
YP_RS00425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YP_RS00435	COG0471	metal ion transport
YP_RS00440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YP_RS00455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YP_RS00460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YP_RS00465	COG0583	DNA-binding transcription factor activity
YP_RS00480	COG3152	Membrane
YP_RS00490	COG1494	fructose-1,6-bisphosphatase
YP_RS00495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YP_RS00500	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YP_RS00555	COG1575	Belongs to the MenA family. Type 1 subfamily
YP_RS00570	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YP_RS00575	COG1609	Transcriptional regulator
YP_RS00585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YP_RS00595	COG4682	membrane
YP_RS00610	COG0626	cystathionine gamma-synthase activity
YP_RS00615	COG0460	homoserine dehydrogenase
YP_RS00615	COG0527	aspartate kinase activity
YP_RS00625	COG2801	Transposase and inactivated derivatives
YP_RS00635	COG1349	DNA-binding transcription factor activity
YP_RS00655	COG0058	SHG alpha-glucan phosphorylase activity
YP_RS00660	COG0058	SHG alpha-glucan phosphorylase activity
YP_RS00665	COG1640	4-alpha-glucanotransferase
YP_RS00700	COG1918	ferrous iron import across plasma membrane
YP_RS00710	COG2183	response to ionizing radiation
YP_RS00715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_RS00740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YP_RS00745	COG1011	Hydrolase
YP_RS00760	COG0494	nUDIX hydrolase
YP_RS00765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YP_RS00795	COG4796	Type ii and iii secretion system protein
YP_RS00820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YP_RS00825	COG0546	phosphoglycolate phosphatase activity
YP_RS00830	COG0180	Tryptophanyl-tRNA synthetase
YP_RS00850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YP_RS00855	COG0402	S-adenosylhomocysteine deaminase activity
YP_RS00880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YP_RS00885	COG0433	COG0433 Predicted ATPase
YP_RS00900	COG1289	transmembrane transporter activity
YP_RS00910	COG1765	OsmC-like protein
YP_RS00920	COG3954	Phosphoribulokinase
YP_RS00930	COG0429	hydrolase of the alpha beta-hydrolase fold
YP_RS00940	COG4521	taurine ABC transporter
YP_RS00950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YP_RS00955	COG2175	clavaminate synthase activity
YP_RS00965	COG1216	Glycosyl transferase, family 2
YP_RS00970	COG0488	(ABC) transporter
YP_RS00985	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YP_RS00990	COG1047	Peptidyl-prolyl cis-trans
YP_RS01000	COG0545	Peptidyl-prolyl cis-trans isomerase
YP_RS01005	COG2964	Protein conserved in bacteria
YP_RS01025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YP_RS01030	COG0049	tRNA binding
YP_RS01060	COG0051	transcription antitermination factor activity, RNA binding
YP_RS01075	COG0089	rRNA binding
YP_RS01085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_RS01095	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YP_RS01100	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YP_RS01110	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YP_RS01115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YP_RS01155	COG1841	ribosomal large subunit assembly
YP_RS01165	COG0201	protein transport
YP_RS01170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YP_RS01185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YP_RS01200	COG0789	Transcriptional regulator
YP_RS01205	COG3036	rescue of stalled ribosome
YP_RS01235	COG0758	DNA mediated transformation
YP_RS01245	COG0551	DNA topoisomerase type I activity
YP_RS01260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YP_RS01300	COG2801	Transposase and inactivated derivatives
YP_RS01350	COG1459	type II secretion system
YP_RS01355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YP_RS01360	COG4969	Belongs to the N-Me-Phe pilin family
YP_RS01370	COG3023	N-Acetylmuramoyl-L-alanine amidase
YP_RS01375	COG3725	Membrane protein required for beta-lactamase induction
YP_RS01380	COG1113	amino acid transport
YP_RS01385	COG2186	Transcriptional regulator
YP_RS01390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YP_RS01395	COG0508	dehydrogenase complex catalyzes the overall conversion of
YP_RS01400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YP_RS01415	COG1049	propionate catabolic process, 2-methylcitrate cycle
YP_RS01425	COG0697	spore germination
YP_RS01445	COG2132	Multicopper oxidase
YP_RS01450	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YP_RS01455	COG0288	reversible hydration of carbon dioxide
YP_RS01460	COG1131	(ABC) transporter
YP_RS01465	COG0842	Transport permease protein
YP_RS01490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YP_RS01495	COG0617	tRNA 3'-terminal CCA addition
YP_RS01500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YP_RS01515	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YP_RS01520	COG1643	Atp-dependent helicase
YP_RS01525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YP_RS01530	COG1120	ATPase activity
YP_RS01535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YP_RS01540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YP_RS01560	COG2860	membrane
YP_RS01580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YP_RS01585	COG3850	Histidine kinase
YP_RS01585	COG2205	protein histidine kinase activity
YP_RS01585	COG3437	response regulator, receiver
YP_RS01585	COG4999	Histidine kinase
YP_RS01590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YP_RS01600	COG3956	TIGRFAM MazG family protein
YP_RS01620	COG0602	queuosine metabolic process
YP_RS01625	COG0720	synthase
YP_RS01675	COG0529	Catalyzes the synthesis of activated sulfate
YP_RS01715	COG4942	peptidase
YP_RS01715	COG1388	LysM domain
YP_RS01720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YP_RS01735	COG0698	ribose 5-phosphate isomerase
YP_RS01740	COG1063	alcohol dehydrogenase
YP_RS01745	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS01750	COG2376	Dihydroxyacetone kinase
YP_RS01765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YP_RS01785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YP_RS01790	COG1858	cytochrome C peroxidase
YP_RS01800	COG4771	TonB-dependent receptor
YP_RS01815	COG0024	Methionine aminopeptidase
YP_RS01825	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YP_RS01825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YP_RS01830	COG1070	Carbohydrate kinase
YP_RS01835	COG3623	hexulose-6-phosphate isomerase
YP_RS01845	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS01850	COG1129	ABC transporter
YP_RS01860	COG1349	DNA-binding transcription factor activity
YP_RS01865	COG0235	Class ii aldolase
YP_RS01870	COG0243	molybdopterin cofactor binding
YP_RS01875	COG0437	4 iron, 4 sulfur cluster binding
YP_RS01880	COG3302	dmso reductase anchor subunit
YP_RS01885	COG3381	protein complex oligomerization
YP_RS01890	COG3038	cytochrome b561
YP_RS01895	COG3783	Cytochrome b(562)
YP_RS01905	COG1879	ABC-type sugar transport system periplasmic component
YP_RS01915	COG1129	ABC transporter
YP_RS01920	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS01925	COG3959	Transketolase, thiamine diphosphate binding domain
YP_RS01930	COG3958	Transketolase
YP_RS01935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YP_RS01975	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YP_RS01995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YP_RS02000	COG1238	metal cluster binding
YP_RS02005	COG2918	glutathione biosynthetic process
YP_RS02015	COG4536	flavin adenine dinucleotide binding
YP_RS02020	COG4137	Cytochrome C assembly protein
YP_RS02025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YP_RS02050	COG3137	Salt-induced outer membrane protein
YP_RS02060	COG3279	Response regulator of the LytR AlgR family
YP_RS02065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YP_RS02070	COG1605	Chorismate mutase
YP_RS02070	COG0287	Prephenate dehydrogenase
YP_RS02075	COG0077	Prephenate dehydratase
YP_RS02075	COG1605	Chorismate mutase
YP_RS02100	COG3162	membrane
YP_RS02110	COG1301	dicarboxylic acid transport
YP_RS02220	COG2391	methyltransferase activity
YP_RS02225	COG0425	Belongs to the sulfur carrier protein TusA family
YP_RS02230	COG0583	DNA-binding transcription factor activity
YP_RS02235	COG0814	amino acid
YP_RS02240	COG0626	cystathionine gamma-synthase activity
YP_RS02250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YP_RS02255	COG4558	Periplasmic binding protein
YP_RS02260	COG3720	iron ion transport
YP_RS02265	COG4771	TonB-dependent receptor
YP_RS02275	COG0702	epimerase
YP_RS02280	COG3721	Heme iron utilization protein
YP_RS02320	COG1358	cellular component organization or biogenesis
YP_RS02380	COG3121	Chaperone
YP_RS02425	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YP_RS02435	COG0735	belongs to the Fur family
YP_RS02440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YP_RS02465	COG1448	Aminotransferase
YP_RS02470	COG2315	Protein conserved in bacteria
YP_RS02475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_RS02480	COG0629	single-stranded DNA binding
YP_RS02490	COG1454	alcohol dehydrogenase
YP_RS02560	COG1309	transcriptional regulator
YP_RS02565	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YP_RS02565	COG0493	'glutamate synthase
YP_RS02570	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YP_RS02575	COG3383	formate dehydrogenase (NAD+) activity
YP_RS02590	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YP_RS02635	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YP_RS02645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YP_RS02650	COG1053	succinate dehydrogenase
YP_RS02665	COG3264	Mechanosensitive ion channel
YP_RS02665	COG1511	domain protein
YP_RS02685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YP_RS02700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YP_RS02705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YP_RS02705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YP_RS02710	COG0802	atpase or kinase
YP_RS02715	COG0860	N-Acetylmuramoyl-L-alanine amidase
YP_RS02735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YP_RS02740	COG0330	HflC and HflK could
YP_RS02745	COG0330	HflC and HflK could
YP_RS02750	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YP_RS02765	COG0557	exoribonuclease II activity
YP_RS02770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YP_RS02775	COG1960	acyl-CoA dehydrogenase activity
YP_RS02780	COG3650	response to hydrogen peroxide
YP_RS02785	COG1073	alpha beta
YP_RS02795	COG0360	Binds together with S18 to 16S ribosomal RNA
YP_RS02805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YP_RS02840	COG3061	Opacity-associated protein A
YP_RS02845	COG0545	Peptidyl-prolyl cis-trans isomerase
YP_RS02855	COG0737	Belongs to the 5'-nucleotidase family
YP_RS02865	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YP_RS02875	COG1253	flavin adenine dinucleotide binding
YP_RS02885	COG0729	surface antigen
YP_RS02890	COG2911	Protein conserved in bacteria
YP_RS02895	COG2105	PFAM AIG2 family protein
YP_RS02900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YP_RS02905	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YP_RS02910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YP_RS02935	COG3423	Transcriptional regulator
YP_RS02945	COG0142	geranyltranstransferase activity
YP_RS02960	COG0697	spore germination
YP_RS02970	COG0642	Histidine kinase
YP_RS02975	COG0745	RESPONSE REGULATOR receiver
YP_RS02980	COG2027	D-alanyl-D-alanine carboxypeptidase
YP_RS02990	COG1534	Rna-binding protein
YP_RS03005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YP_RS03015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YP_RS03035	COG0195	Participates in both transcription termination and antitermination
YP_RS03065	COG2801	Transposase and inactivated derivatives
YP_RS03080	COG0513	Belongs to the DEAD box helicase family
YP_RS03100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YP_RS03110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YP_RS03120	COG0826	peptidase U32
YP_RS03125	COG0826	peptidase U32
YP_RS03135	COG3154	lipid carrier protein
YP_RS03140	COG3153	acetyltransferase
YP_RS03160	COG1653	transport
YP_RS03165	COG1175	transmembrane transport
YP_RS03170	COG0395	ABC-type sugar transport system, permease component
YP_RS03190	COG0702	epimerase
YP_RS03195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YP_RS03200	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YP_RS03205	COG3454	Phosphonate metabolism
YP_RS03210	COG4778	phosphonate C-P lyase system protein PhnL
YP_RS03215	COG4107	phosphonate C-P lyase system protein PhnK
YP_RS03220	COG3627	carbon phosphorus lyase activity
YP_RS03225	COG3626	phosphonate metabolism
YP_RS03230	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YP_RS03235	COG3624	Phosphonate C-P lyase system protein PhnG
YP_RS03240	COG2188	Transcriptional regulator
YP_RS03255	COG4608	Belongs to the ABC transporter superfamily
YP_RS03260	COG0444	Belongs to the ABC transporter superfamily
YP_RS03265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YP_RS03270	COG0601	transmembrane transport
YP_RS03280	COG2731	YhcH YjgK YiaL family protein
YP_RS03290	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YP_RS03300	COG0525	valine-tRNA ligase activity
YP_RS03305	COG2927	DNA polymerase III (CHI subunit)
YP_RS03315	COG0795	lipopolysaccharide-transporting ATPase activity
YP_RS03320	COG0795	lipopolysaccharide-transporting ATPase activity
YP_RS03330	COG0582	viral genome integration into host DNA
YP_RS03360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YP_RS03365	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YP_RS03370	COG0564	pseudouridine synthase activity
YP_RS03380	COG0542	response to heat
YP_RS03420	COG5544	Lipoprotein
YP_RS03425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YP_RS03430	COG0045	succinate-CoA ligase (ADP-forming) activity
YP_RS03430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YP_RS03430	COG1042	CoA-binding domain protein
YP_RS03435	COG3148	PFAM DTW domain containing protein
YP_RS03440	COG3118	belongs to the thioredoxin family
YP_RS03445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YP_RS03450	COG2814	Major facilitator Superfamily
YP_RS03455	COG1566	PFAM secretion protein HlyD family protein
YP_RS03460	COG1846	Transcriptional regulator
YP_RS03470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YP_RS03475	COG2814	Major facilitator Superfamily
YP_RS03515	COG0765	amino acid transport
YP_RS03525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YP_RS03540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YP_RS03560	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YP_RS03570	COG1960	acyl-CoA dehydrogenase activity
YP_RS03580	COG0121	glutamine amidotransferase
YP_RS03585	COG3034	peptidoglycan biosynthetic process
YP_RS03595	COG1805	sodium ion transport
YP_RS03600	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YP_RS03620	COG1477	protein flavinylation
YP_RS03640	COG2195	Cleaves the N-terminal amino acid of tripeptides
YP_RS03700	COG2226	methyltransferase
YP_RS03735	COG1940	carbohydrate kinase activity
YP_RS03740	COG0419	ATPase involved in DNA repair
YP_RS03745	COG0420	3'-5' exonuclease activity
YP_RS03755	COG0745	RESPONSE REGULATOR receiver
YP_RS03760	COG5002	protein histidine kinase activity
YP_RS03780	COG0366	Alpha amylase catalytic
YP_RS03805	COG0450	alkyl hydroperoxide reductase
YP_RS03825	COG1862	Preprotein translocase
YP_RS03830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YP_RS03835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YP_RS03860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YP_RS03860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YP_RS03875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YP_RS03880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YP_RS03900	COG0142	geranyltranstransferase activity
YP_RS03920	COG0693	protein deglycase activity
YP_RS03925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YP_RS03935	COG2814	Major facilitator Superfamily
YP_RS03945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YP_RS03950	COG1845	cytochrome c oxidase, subunit III
YP_RS03955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YP_RS03960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YP_RS03970	COG2223	nitrite transmembrane transporter activity
YP_RS03975	COG3056	Lipoprotein
YP_RS03980	COG0271	Belongs to the BolA IbaG family
YP_RS04005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YP_RS04010	COG0776	regulation of translation
YP_RS04015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YP_RS04020	COG1555	photosystem II stabilization
YP_RS04025	COG0824	Thioesterase
YP_RS04035	COG4533	DNA binding
YP_RS04050	COG1522	sequence-specific DNA binding
YP_RS04055	COG1132	(ABC) transporter
YP_RS04060	COG1132	(ABC) transporter
YP_RS04065	COG0347	Belongs to the P(II) protein family
YP_RS04070	COG0004	ammonium transporteR
YP_RS04075	COG1946	Acyl-CoA thioesterase
YP_RS04080	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YP_RS04085	COG3695	enzyme binding
YP_RS04105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YP_RS04115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YP_RS04120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YP_RS04125	COG1309	transcriptional regulator
YP_RS04130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YP_RS04135	COG3264	Mechanosensitive ion channel
YP_RS04135	COG1196	nuclear chromosome segregation
YP_RS04160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YP_RS04190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YP_RS04190	COG0543	2 iron, 2 sulfur cluster binding
YP_RS04210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YP_RS04250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YP_RS04270	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YP_RS04275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YP_RS04280	COG4651	solute:proton antiporter activity
YP_RS04280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YP_RS04285	COG2223	nitrite transmembrane transporter activity
YP_RS04290	COG0737	Belongs to the 5'-nucleotidase family
YP_RS04295	COG0737	Belongs to the 5'-nucleotidase family
YP_RS04300	COG0737	Belongs to the 5'-nucleotidase family
YP_RS04315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YP_RS04320	COG3735	TraB family
YP_RS04325	COG2217	Heavy metal translocating P-type atpase
YP_RS04330	COG0789	Transcriptional regulator
YP_RS04335	COG1585	Membrane protein implicated in regulation of membrane protease activity
YP_RS04340	COG0330	HflC and HflK could
YP_RS04345	COG3118	belongs to the thioredoxin family
YP_RS04350	COG0300	oxidoreductase activity
YP_RS04355	COG2755	lipolytic protein G-D-S-L family
YP_RS04360	COG4181	ATPase activity
YP_RS04365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YP_RS04370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YP_RS04375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YP_RS04385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YP_RS04405	COG2501	S4 domain
YP_RS04450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YP_RS04455	COG4589	Belongs to the CDS family
YP_RS04465	COG2267	carboxylic ester hydrolase activity
YP_RS04470	COG2453	phosphatase
YP_RS04470	COG0671	phosphoesterase, PA-phosphatase related
YP_RS04495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YP_RS04510	COG1067	ATP-dependent peptidase activity
YP_RS04530	COG3082	Protein of unknown function (DUF1414)
YP_RS04535	COG3083	sulfuric ester hydrolase activity
YP_RS04550	COG3157	Type VI secretion system effector, Hcp
YP_RS04570	COG2723	6-phospho-beta-galactosidase activity
YP_RS04575	COG1737	Transcriptional regulator
YP_RS04595	COG3299	homolog of phage Mu protein gp47
YP_RS04635	COG4386	tail sheath protein
YP_RS04655	COG3622	Belongs to the hyi family
YP_RS04660	COG1349	DNA-binding transcription factor activity
YP_RS04670	COG3395	kinase activity
YP_RS04715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YP_RS04740	COG2223	nitrite transmembrane transporter activity
YP_RS04745	COG2198	Histidine kinase
YP_RS04745	COG0642	Histidine kinase
YP_RS04750	COG2198	Histidine kinase
YP_RS04750	COG0642	Histidine kinase
YP_RS04760	COG2205	protein histidine kinase activity
YP_RS04760	COG0784	Response regulator, receiver
YP_RS04790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YP_RS04805	COG0814	amino acid
YP_RS04830	COG0697	spore germination
YP_RS04840	COG1982	Orn Lys Arg decarboxylase major
YP_RS04845	COG0531	amino acid
YP_RS04850	COG1174	glycine betaine transport
YP_RS04855	COG1125	glycine betaine transport
YP_RS04860	COG1174	glycine betaine transport
YP_RS04865	COG1732	Glycine betaine
YP_RS04870	COG1732	Glycine betaine
YP_RS04875	COG2897	thiosulfate sulfurtransferase activity
YP_RS04895	COG1122	ATPase activity
YP_RS04915	COG4807	Protein conserved in bacteria
YP_RS04930	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YP_RS04940	COG2261	transglycosylase associated protein
YP_RS04960	COG0277	FAD linked oxidase domain protein
YP_RS04965	COG1686	Belongs to the peptidase S11 family
YP_RS04975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YP_RS04995	COG0513	Belongs to the DEAD box helicase family
YP_RS05005	COG3328	transposase activity
YP_RS05030	COG0513	Belongs to the DEAD box helicase family
YP_RS05035	COG1309	transcriptional regulator
YP_RS05045	COG1131	(ABC) transporter
YP_RS05050	COG0842	Transport permease protein
YP_RS05055	COG0842	Transport permease protein
YP_RS05075	COG1902	pentaerythritol trinitrate reductase activity
YP_RS05095	COG2211	Major facilitator Superfamily
YP_RS05105	COG2211	Major facilitator Superfamily
YP_RS05110	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YP_RS05120	COG0583	DNA-binding transcription factor activity
YP_RS05125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YP_RS05155	COG0670	Belongs to the BI1 family
YP_RS05160	COG0314	molybdopterin synthase activity
YP_RS05165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YP_RS05175	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YP_RS05185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YP_RS05190	COG4628	conserved protein (DUF2132)
YP_RS05200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YP_RS05210	COG2226	methyltransferase
YP_RS05235	COG0561	phosphatase activity
YP_RS05245	COG4149	molybdate abc transporter
YP_RS05250	COG0725	ABC transporter, periplasmic molybdate-binding protein
YP_RS05260	COG3585	molybdate ion transport
YP_RS05260	COG2005	Transcriptional regulator
YP_RS05265	COG1119	ATPase activity
YP_RS05280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YP_RS05285	COG1085	galactose-1-phosphate uridylyltransferase
YP_RS05300	COG2017	converts alpha-aldose to the beta-anomer
YP_RS05315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YP_RS05320	COG1230	cation diffusion facilitator family transporter
YP_RS05355	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YP_RS05360	COG2885	chlorophyll binding
YP_RS05370	COG3064	Membrane
YP_RS05370	COG3064	Membrane
YP_RS05375	COG0848	biopolymer transport protein
YP_RS05380	COG0811	peptide transport
YP_RS05385	COG0824	Thioesterase
YP_RS05390	COG3790	cyd operon protein YbgE
YP_RS05395	COG4890	Cyd operon protein YbgT
YP_RS05400	COG1294	oxidase, subunit
YP_RS05405	COG1271	oxidase subunit
YP_RS05410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YP_RS05420	COG0508	dehydrogenase complex catalyzes the overall conversion of
YP_RS05425	COG0567	Dehydrogenase, E1 component
YP_RS05435	COG1053	succinate dehydrogenase
YP_RS05440	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YP_RS05445	COG2009	succinate dehydrogenase
YP_RS05460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YP_RS05465	COG0497	DNA recombination
YP_RS05470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YP_RS05480	COG2867	negative regulation of translational initiation
YP_RS05500	COG0582	viral genome integration into host DNA
YP_RS05560	COG3657	addiction module killer protein
YP_RS05580	COG0582	viral genome integration into host DNA
YP_RS05585	COG2963	transposase activity
YP_RS05590	COG0582	viral genome integration into host DNA
YP_RS05600	COG0596	Alpha beta hydrolase
YP_RS05620	COG0735	belongs to the Fur family
YP_RS05640	COG2190	(PTS) system
YP_RS05640	COG1263	PTS System
YP_RS05640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YP_RS05650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YP_RS05655	COG1940	carbohydrate kinase activity
YP_RS05655	COG1846	Transcriptional regulator
YP_RS05665	COG0367	asparagine synthase
YP_RS05705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YP_RS05715	COG1702	phosphate starvation-inducible protein PhoH
YP_RS05725	COG4535	Mg2 and Co2 transporter CorC
YP_RS05730	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YP_RS05740	COG0765	amino acid transport
YP_RS05745	COG0765	amino acid transport
YP_RS05750	COG1126	abc transporter atp-binding protein
YP_RS05755	COG2888	peptidyl-tyrosine sulfation
YP_RS05770	COG1466	dna polymerase III delta subunit
YP_RS05780	COG0799	negative regulation of ribosome biogenesis
YP_RS05790	COG0768	penicillin binding
YP_RS05795	COG0772	Belongs to the SEDS family
YP_RS05800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YP_RS05805	COG1686	Belongs to the peptidase S11 family
YP_RS05825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YP_RS05835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YP_RS05845	COG1278	Cold shock
YP_RS05850	COG2197	response regulator
YP_RS05875	COG5265	(ABC) transporter
YP_RS05885	COG3718	enzyme involved in inositol metabolism
YP_RS05895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YP_RS05900	COG0673	inositol 2-dehydrogenase activity
YP_RS05905	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS05910	COG1129	ABC transporter
YP_RS05925	COG3962	Belongs to the TPP enzyme family
YP_RS05945	COG2373	Large extracellular alpha-helical protein
YP_RS05950	COG4953	penicillin-binding protein 1C
YP_RS05955	COG3423	Transcriptional regulator
YP_RS06005	COG2850	peptidyl-arginine hydroxylation
YP_RS06010	COG3328	transposase activity
YP_RS06025	COG1472	Belongs to the glycosyl hydrolase 3 family
YP_RS06045	COG0656	L-ascorbic acid biosynthetic process
YP_RS06050	COG0667	Aldo Keto reductase
YP_RS06070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YP_RS06085	COG3130	regulation of translation
YP_RS06095	COG3009	Protein conserved in bacteria
YP_RS06100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YP_RS06100	COG3008	intermembrane lipid transfer
YP_RS06105	COG2995	paraquat-inducible protein a
YP_RS06110	COG0488	(ABC) transporter
YP_RS06120	COG0633	Ferredoxin
YP_RS06120	COG3217	Mosc domain protein beta barrel domain protein
YP_RS06135	COG0308	aminopeptidase N
YP_RS06155	COG1448	Aminotransferase
YP_RS06160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YP_RS06165	COG3108	Peptidase M15
YP_RS06170	COG2989	Protein conserved in bacteria
YP_RS06200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YP_RS06210	COG3173	Aminoglycoside phosphotransferase
YP_RS06225	COG1278	Cold shock
YP_RS06235	COG5383	Protein conserved in bacteria
YP_RS06250	COG0658	competence protein
YP_RS06250	COG2333	competence protein COMEC
YP_RS06265	COG0539	negative regulation of cytoplasmic translation
YP_RS06290	COG5295	Hep Hag repeat protein
YP_RS06290	COG5295	Hep Hag repeat protein
YP_RS06295	COG0252	asparaginase activity
YP_RS06300	COG1944	ATP diphosphatase activity
YP_RS06305	COG2116	formate transmembrane transporter activity
YP_RS06310	COG1882	Formate acetyltransferase
YP_RS06320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YP_RS06335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YP_RS06345	COG3107	peptidoglycan biosynthetic process
YP_RS06345	COG1674	ftsk spoiiie
YP_RS06355	COG0492	ferredoxin-NADP+ reductase activity
YP_RS06370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YP_RS06380	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YP_RS06390	COG0542	response to heat
YP_RS06400	COG1278	Cold shock
YP_RS06410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YP_RS06415	COG2990	Protein conserved in bacteria
YP_RS06420	COG3593	DNA synthesis involved in DNA repair
YP_RS06425	COG2431	L-lysine efflux transmembrane transporter activity
YP_RS06435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YP_RS06440	COG0028	Belongs to the TPP enzyme family
YP_RS06445	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YP_RS06450	COG0702	epimerase
YP_RS06455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YP_RS06465	COG1605	Chorismate mutase
YP_RS06470	COG1126	abc transporter atp-binding protein
YP_RS06475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YP_RS06480	COG4215	(ABC) transporter
YP_RS06485	COG4160	amino acid transport
YP_RS06510	COG1120	ATPase activity
YP_RS06540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YP_RS06555	COG1177	transmembrane transport
YP_RS06560	COG1176	ABC-type spermidine putrescine transport system, permease component I
YP_RS06565	COG3842	ATPase activity
YP_RS06570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YP_RS06605	COG0671	phosphoesterase, PA-phosphatase related
YP_RS06615	COG1349	DNA-binding transcription factor activity
YP_RS06620	COG0814	amino acid
YP_RS06630	COG1686	Belongs to the peptidase S11 family
YP_RS06635	COG2011	ABC-type metal ion transport system permease component
YP_RS06660	COG0625	glutathione transferase activity
YP_RS06665	COG4771	TonB-dependent receptor
YP_RS06675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YP_RS06685	COG0833	amino acid
YP_RS06690	COG0583	DNA-binding transcription factor activity
YP_RS06695	COG2855	membrane
YP_RS06705	COG3188	usher protein
YP_RS06710	COG3121	Chaperone
YP_RS06725	COG3710	Transcriptional regulator
YP_RS06730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YP_RS06730	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YP_RS06730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YP_RS06735	COG1105	Belongs to the carbohydrate kinase PfkB family
YP_RS06745	COG0494	nUDIX hydrolase
YP_RS06755	COG1129	ABC transporter
YP_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS06815	COG0246	Mannitol dehydrogenase
YP_RS06820	COG2186	Transcriptional regulator
YP_RS06830	COG0523	cobalamin synthesis protein
YP_RS06835	COG0671	phosphoesterase, PA-phosphatase related
YP_RS06840	COG0791	NLP P60 protein
YP_RS06845	COG2200	EAL domain
YP_RS06850	COG4166	transmembrane transport
YP_RS06855	COG4174	ABC transporter (Permease)
YP_RS06860	COG4239	(ABC) transporter, permease
YP_RS06865	COG4172	Belongs to the ABC transporter superfamily
YP_RS06875	COG2814	Major facilitator Superfamily
YP_RS06880	COG1187	pseudouridine synthase activity
YP_RS06885	COG1061	Type III restriction enzyme res subunit
YP_RS06915	COG3070	regulator of competence-specific genes
YP_RS06920	COG1289	transmembrane transporter activity
YP_RS06925	COG3304	Inner membrane component domain
YP_RS06930	COG0210	DNA helicase
YP_RS06945	COG1832	CoA-binding protein
YP_RS06965	COG2920	part of a sulfur-relay system
YP_RS07015	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS07025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YP_RS07030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YP_RS07035	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS07040	COG3425	synthase
YP_RS07050	COG1024	Enoyl-CoA hydratase
YP_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS07065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YP_RS07070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YP_RS07205	COG0488	(ABC) transporter
YP_RS07215	COG3328	transposase activity
YP_RS07225	COG0303	'Molybdopterin
YP_RS07235	COG1136	(ABC) transporter
YP_RS07270	COG0583	DNA-binding transcription factor activity
YP_RS07275	COG0477	Major facilitator Superfamily
YP_RS07285	COG2311	Membrane
YP_RS07300	COG4211	Belongs to the binding-protein-dependent transport system permease family
YP_RS07305	COG2949	membrane
YP_RS07320	COG1346	cytolysis
YP_RS07330	COG2814	Major facilitator Superfamily
YP_RS07365	COG0489	protein tyrosine kinase activity
YP_RS07380	COG2982	Protein involved in outer membrane biogenesis
YP_RS07385	COG1253	flavin adenine dinucleotide binding
YP_RS07390	COG4114	ferric iron reductase
YP_RS07395	COG0076	glutamate decarboxylase activity
YP_RS07400	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YP_RS07415	COG1120	ATPase activity
YP_RS07420	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YP_RS07425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YP_RS07430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YP_RS07445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YP_RS07450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YP_RS07460	COG0140	phosphoribosyl-ATP diphosphatase activity
YP_RS07460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YP_RS07480	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YP_RS07480	COG0131	Imidazoleglycerol-phosphate dehydratase
YP_RS07490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YP_RS07500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YP_RS07510	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS07515	COG1129	ABC transporter
YP_RS07520	COG1129	ABC transporter
YP_RS07525	COG0371	Dehydrogenase
YP_RS07535	COG0531	amino acid
YP_RS07540	COG2925	Exonuclease
YP_RS07555	COG1388	LysM domain
YP_RS07555	COG1470	cell adhesion involved in biofilm formation
YP_RS07560	COG2271	Major facilitator Superfamily
YP_RS07565	COG3011	Protein conserved in bacteria
YP_RS07570	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS07580	COG4948	Mandelate Racemase Muconate Lactonizing
YP_RS07595	COG0534	Mate efflux family protein
YP_RS07615	COG3122	Protein conserved in bacteria
YP_RS07640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YP_RS07660	COG2223	nitrite transmembrane transporter activity
YP_RS07695	COG1132	(ABC) transporter
YP_RS07705	COG2207	Transcriptional regulator
YP_RS07740	COG1113	amino acid transport
YP_RS07765	COG1496	oxidoreductase activity
YP_RS07770	COG2226	methyltransferase
YP_RS07780	COG5002	protein histidine kinase activity
YP_RS07780	COG5001	Diguanylate cyclase
YP_RS07780	COG3447	MASE1 domain protein
YP_RS07820	COG3842	ATPase activity
YP_RS07825	COG0395	ABC-type sugar transport system, permease component
YP_RS07830	COG1175	transmembrane transport
YP_RS07840	COG0673	inositol 2-dehydrogenase activity
YP_RS07850	COG2188	Transcriptional regulator
YP_RS07990	COG2197	response regulator
YP_RS08000	COG3136	membrane protein required for alginate biosynthesis
YP_RS08020	COG1113	amino acid transport
YP_RS08040	COG2822	iron ion transport
YP_RS08045	COG0672	)-iron permease
YP_RS08060	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YP_RS08060	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YP_RS08060	COG0506	proline dehydrogenase activity
YP_RS08075	COG1126	abc transporter atp-binding protein
YP_RS08080	COG0765	amino acid transport
YP_RS08085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YP_RS08100	COG1191	sigma factor activity
YP_RS08135	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YP_RS08140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YP_RS08145	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YP_RS08160	COG1677	Flagellar hook-basal body complex protein FliE
YP_RS08180	COG1157	protein secretion by the type III secretion system
YP_RS08195	COG1580	Controls the rotational direction of flagella during chemotaxis
YP_RS08220	COG1987	bacterial-type flagellum assembly
YP_RS08240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YP_RS08245	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS08250	COG1129	ABC transporter
YP_RS08260	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS08265	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS08265	COG3347	Dehydrogenase
YP_RS08270	COG2390	Transcriptional regulator
YP_RS08280	COG1256	bacterial-type flagellum assembly
YP_RS08320	COG1558	bacterial-type flagellum-dependent cell motility
YP_RS08325	COG1815	bacterial-type flagellum-dependent cell motility
YP_RS08335	COG2747	anti-sigma28 factor FlgM
YP_RS08340	COG3418	PFAM FlgN family protein
YP_RS08365	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YP_RS08370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YP_RS08400	COG2372	response to copper ion
YP_RS08410	COG1528	Iron-storage protein
YP_RS08425	COG1770	oligopeptidase
YP_RS08440	COG3141	response to X-ray
YP_RS08445	COG0513	Belongs to the DEAD box helicase family
YP_RS08470	COG1760	l-serine dehydratase
YP_RS08475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YP_RS08480	COG2368	4-hydroxyphenylacetate
YP_RS08495	COG3971	2-oxopent-4-enoate hydratase activity
YP_RS08505	COG3384	dioxygenase
YP_RS08510	COG1012	belongs to the aldehyde dehydrogenase family
YP_RS08525	COG1846	Transcriptional regulator
YP_RS08530	COG1253	flavin adenine dinucleotide binding
YP_RS08535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YP_RS08535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YP_RS08540	COG3715	PTS system
YP_RS08545	COG3716	PTS system mannose fructose sorbose family IID component
YP_RS08610	COG4771	TonB-dependent receptor
YP_RS08615	COG1021	2,3-dihydroxybenzoate-AMP ligase
YP_RS08635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YP_RS08635	COG2226	methyltransferase
YP_RS08635	COG3433	isochorismatase activity
YP_RS08650	COG1132	(ABC) transporter
YP_RS08655	COG2814	Major facilitator Superfamily
YP_RS08660	COG1169	isochorismate synthase
YP_RS08665	COG0582	viral genome integration into host DNA
YP_RS08675	COG3121	Chaperone
YP_RS08685	COG3188	usher protein
YP_RS08700	COG2205	protein histidine kinase activity
YP_RS08700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YP_RS08710	COG0427	acetyl-CoA hydrolase
YP_RS08715	COG2030	dehydratase
YP_RS08740	COG2814	Major facilitator Superfamily
YP_RS08755	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YP_RS08760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YP_RS08770	COG1349	DNA-binding transcription factor activity
YP_RS08775	COG2066	Belongs to the glutaminase family
YP_RS08785	COG0672	)-iron permease
YP_RS08800	COG0577	efflux transmembrane transporter activity
YP_RS08800	COG1136	(ABC) transporter
YP_RS08810	COG1136	(ABC) transporter
YP_RS08810	COG0577	efflux transmembrane transporter activity
YP_RS08830	COG0006	proline dipeptidase activity
YP_RS08835	COG0457	Tetratricopeptide repeat
YP_RS08840	COG1649	PFAM Uncharacterised BCR, COG1649
YP_RS08840	COG0726	polysaccharide deacetylase
YP_RS08845	COG1215	transferase activity, transferring glycosyl groups
YP_RS08850	COG3658	cytochrome
YP_RS08860	COG3328	transposase activity
YP_RS08870	COG1702	phosphate starvation-inducible protein PhoH
YP_RS08875	COG0387	Pfam Sodium calcium exchanger
YP_RS08880	COG3850	Histidine kinase
YP_RS08885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YP_RS08970	COG3121	Chaperone
YP_RS08990	COG3008	intermembrane lipid transfer
YP_RS08995	COG2995	paraquat-inducible protein a
YP_RS09000	COG1956	GAF domain-containing protein
YP_RS09010	COG0793	Belongs to the peptidase S41A family
YP_RS09020	COG3539	Fimbrial protein
YP_RS09025	COG3121	Chaperone
YP_RS09040	COG3121	Chaperone
YP_RS09045	COG2814	Major facilitator Superfamily
YP_RS09050	COG0823	Involved in the tonB-independent uptake of proteins
YP_RS09060	COG3023	N-Acetylmuramoyl-L-alanine amidase
YP_RS09065	COG1823	symporter activity
YP_RS09070	COG1988	membrane-bound metal-dependent
YP_RS09075	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YP_RS09080	COG1653	transport
YP_RS09085	COG3842	ATPase activity
YP_RS09090	COG0395	ABC-type sugar transport system, permease component
YP_RS09095	COG1175	transmembrane transport
YP_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS09115	COG1917	Cupin 2, conserved barrel domain protein
YP_RS09120	COG3328	transposase activity
YP_RS09125	COG3134	Outer membrane lipoprotein
YP_RS09130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YP_RS09145	COG4591	ABC-type transport system involved in lipoprotein release permease component
YP_RS09150	COG1940	carbohydrate kinase activity
YP_RS09165	COG2850	peptidyl-arginine hydroxylation
YP_RS09175	COG0745	RESPONSE REGULATOR receiver
YP_RS09185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YP_RS09205	COG1187	pseudouridine synthase activity
YP_RS09210	COG0538	isocitrate dehydrogenase activity
YP_RS09225	COG0840	transmembrane signaling receptor activity
YP_RS09230	COG0702	epimerase
YP_RS09235	COG1733	regulation of RNA biosynthetic process
YP_RS09260	COG1522	sequence-specific DNA binding
YP_RS09270	COG0604	alcohol dehydrogenase
YP_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS09270	COG3321	synthase
YP_RS09300	COG1285	pathogenesis
YP_RS09325	COG1360	Flagellar Motor Protein
YP_RS09330	COG2198	Histidine kinase
YP_RS09330	COG0643	Histidine kinase
YP_RS09335	COG0835	chemotaxis
YP_RS09340	COG2271	Major facilitator Superfamily
YP_RS09345	COG0251	oxidation-reduction process
YP_RS09355	COG2964	Protein conserved in bacteria
YP_RS09360	COG3328	transposase activity
YP_RS09380	COG0840	transmembrane signaling receptor activity
YP_RS09385	COG0840	transmembrane signaling receptor activity
YP_RS09390	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YP_RS09400	COG0745	RESPONSE REGULATOR receiver
YP_RS09405	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YP_RS09415	COG3023	N-Acetylmuramoyl-L-alanine amidase
YP_RS09425	COG5295	Hep Hag repeat protein
YP_RS09435	COG3328	transposase activity
YP_RS09440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YP_RS09480	COG0402	S-adenosylhomocysteine deaminase activity
YP_RS09495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YP_RS09500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YP_RS09505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YP_RS09545	COG3328	transposase activity
YP_RS09570	COG0500	methyltransferase
YP_RS09610	COG5002	protein histidine kinase activity
YP_RS09665	COG0012	GTP binding
YP_RS09685	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YP_RS09715	COG2890	protein-(glutamine-N5) methyltransferase activity
YP_RS09735	COG0659	secondary active sulfate transmembrane transporter activity
YP_RS09760	COG3833	ABC-type maltose transport systems, permease component
YP_RS09765	COG1176	ABC-type spermidine putrescine transport system, permease component I
YP_RS09780	COG3842	ATPase activity
YP_RS09785	COG0584	glycerophosphoryl diester phosphodiesterase
YP_RS09790	COG1940	carbohydrate kinase activity
YP_RS09805	COG3381	protein complex oligomerization
YP_RS09820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YP_RS09825	COG0673	inositol 2-dehydrogenase activity
YP_RS09830	COG0728	peptidoglycan biosynthetic process
YP_RS09855	COG3102	Protein conserved in bacteria
YP_RS09875	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YP_RS09880	COG1801	Protein of unknown function DUF72
YP_RS09890	COG0494	nUDIX hydrolase
YP_RS09915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YP_RS09925	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YP_RS09930	COG0739	heme binding
YP_RS09935	COG1560	Kdo2-lipid A biosynthetic process
YP_RS09940	COG0469	pyruvate kinase activity
YP_RS09945	COG1737	Transcriptional regulator
YP_RS09950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YP_RS09955	COG0800	Aldolase
YP_RS09970	COG0251	oxidation-reduction process
YP_RS09975	COG1199	ATP-dependent helicase activity
YP_RS09985	COG3065	identical protein binding
YP_RS09990	COG0318	PFAM AMP-dependent synthetase and ligase
YP_RS09995	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YP_RS10000	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YP_RS10005	COG2894	cell division
YP_RS10020	COG2951	lytic endotransglycosylase activity
YP_RS10025	COG0179	Fumarylacetoacetate (FAA) hydrolase
YP_RS10035	COG0582	viral genome integration into host DNA
YP_RS10095	COG3328	transposase activity
YP_RS10105	COG1104	cysteine desulfurase activity
YP_RS10135	COG2719	SpoVR family
YP_RS10145	COG2814	Major facilitator Superfamily
YP_RS10155	COG0583	DNA-binding transcription factor activity
YP_RS10170	COG2766	serine protein kinase
YP_RS10175	COG3713	MltA-interacting MipA family protein
YP_RS10195	COG3139	Protein of unknown function (DUF1315)
YP_RS10200	COG1335	isochorismatase
YP_RS10205	COG0252	asparaginase activity
YP_RS10210	COG0616	signal peptide processing
YP_RS10215	COG0778	Nitroreductase
YP_RS10220	COG0709	Synthesizes selenophosphate from selenide and ATP
YP_RS10225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YP_RS10235	COG0494	nUDIX hydrolase
YP_RS10240	COG0708	Exodeoxyribonuclease III
YP_RS10245	COG0583	DNA-binding transcription factor activity
YP_RS10255	COG0788	formyltetrahydrofolate deformylase activity
YP_RS10265	COG0745	RESPONSE REGULATOR receiver
YP_RS10285	COG1454	alcohol dehydrogenase
YP_RS10285	COG1012	belongs to the aldehyde dehydrogenase family
YP_RS10290	COG2095	MarC family integral membrane protein
YP_RS10300	COG0601	transmembrane transport
YP_RS10305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YP_RS10310	COG0444	Belongs to the ABC transporter superfamily
YP_RS10315	COG4608	Belongs to the ABC transporter superfamily
YP_RS10350	COG2350	Protein conserved in bacteria
YP_RS10355	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YP_RS10360	COG3328	transposase activity
YP_RS10395	COG3047	cAMP biosynthetic process
YP_RS10415	COG0135	phosphoribosylanthranilate isomerase activity
YP_RS10415	COG0134	indole-3-glycerol-phosphate synthase activity
YP_RS10425	COG0512	Glutamine amidotransferase of anthranilate synthase
YP_RS10450	COG0009	L-threonylcarbamoyladenylate synthase
YP_RS10455	COG1187	pseudouridine synthase activity
YP_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS10470	COG0616	signal peptide processing
YP_RS10490	COG0583	DNA-binding transcription factor activity
YP_RS10500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YP_RS10510	COG0671	phosphoesterase, PA-phosphatase related
YP_RS10515	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YP_RS10520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YP_RS10535	COG0023	Translation Initiation Factor
YP_RS10555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YP_RS10560	COG2879	small protein
YP_RS10565	COG1966	Carbon starvation protein
YP_RS10575	COG2271	Major facilitator Superfamily
YP_RS10580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YP_RS10585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YP_RS10595	COG4659	FMN binding
YP_RS10600	COG4658	electron transport chain
YP_RS10605	COG3708	Transcriptional regulator
YP_RS10605	COG2207	Transcriptional regulator
YP_RS10635	COG1132	(ABC) transporter
YP_RS10645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YP_RS10650	COG2274	protein secretion by the type I secretion system
YP_RS10665	COG1879	ABC-type sugar transport system periplasmic component
YP_RS10670	COG1129	ABC transporter
YP_RS10675	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS10685	COG0673	inositol 2-dehydrogenase activity
YP_RS10690	COG0385	Bile acid
YP_RS10700	COG5339	Protein conserved in bacteria
YP_RS10710	COG0114	fumarate hydratase activity
YP_RS10725	COG1940	carbohydrate kinase activity
YP_RS10730	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YP_RS10735	COG0038	chloride channel
YP_RS10745	COG1609	Transcriptional regulator
YP_RS10765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YP_RS10775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YP_RS10800	COG0028	Belongs to the TPP enzyme family
YP_RS10805	COG0440	acetolactate synthase activity
YP_RS10810	COG1011	Hydrolase
YP_RS10830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YP_RS10835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YP_RS10845	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YP_RS10850	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YP_RS10865	COG0531	amino acid
YP_RS10875	COG0745	RESPONSE REGULATOR receiver
YP_RS10880	COG2205	protein histidine kinase activity
YP_RS10895	COG2205	protein histidine kinase activity
YP_RS10900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YP_RS10935	COG3038	cytochrome b561
YP_RS10950	COG3591	Belongs to the peptidase S1B family
YP_RS10965	COG1643	Atp-dependent helicase
YP_RS10975	COG2390	Transcriptional regulator
YP_RS10980	COG0246	Mannitol dehydrogenase
YP_RS10985	COG3784	Protein of unknown function (DUF1318)
YP_RS10995	COG2911	Protein conserved in bacteria
YP_RS11000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YP_RS11005	COG3187	Heat shock protein
YP_RS11010	COG3042	response to heat
YP_RS11015	COG1285	pathogenesis
YP_RS11025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YP_RS11025	COG1013	pyruvate-flavodoxin oxidoreductase activity
YP_RS11025	COG0674	pyruvate-flavodoxin oxidoreductase activity
YP_RS11025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YP_RS11035	COG0657	acetylesterase activity
YP_RS11050	COG4166	transmembrane transport
YP_RS11055	COG2866	Carboxypeptidase
YP_RS11060	COG4948	Mandelate Racemase Muconate Lactonizing
YP_RS11065	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YP_RS11080	COG5642	Protein of unknown function (DUF2384)
YP_RS11085	COG5654	RES domain protein
YP_RS11095	COG3106	COG3106 Predicted ATPase
YP_RS11105	COG1983	PspC domain protein
YP_RS11115	COG1842	Phage shock protein A
YP_RS11120	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YP_RS11140	COG4166	transmembrane transport
YP_RS11145	COG4168	peptide transport system, permease
YP_RS11150	COG4171	peptide transport system, permease
YP_RS11160	COG4172	Belongs to the ABC transporter superfamily
YP_RS11165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YP_RS11165	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YP_RS11170	COG3104	oligopeptide transport
YP_RS11185	COG0625	glutathione transferase activity
YP_RS11205	COG3895	Periplasmic Protein
YP_RS11215	COG3133	Outer membrane lipoprotein
YP_RS11225	COG4989	oxidoreductase activity
YP_RS11230	COG3313	Fe-S protein
YP_RS11235	COG2194	sulfuric ester hydrolase activity
YP_RS11240	COG1309	transcriptional regulator
YP_RS11245	COG1902	pentaerythritol trinitrate reductase activity
YP_RS11255	COG0346	lactoylglutathione lyase activity
YP_RS11260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YP_RS11265	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YP_RS11275	COG0791	NLP P60 protein
YP_RS11290	COG0583	DNA-binding transcription factor activity
YP_RS11295	COG2814	Major facilitator Superfamily
YP_RS11300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YP_RS11305	COG0307	riboflavin synthase, alpha
YP_RS11355	COG1376	ErfK ybiS ycfS ynhG family protein
YP_RS11355	COG1388	LysM domain
YP_RS11370	COG0719	Fe-S assembly protein
YP_RS11375	COG0396	ATPase activity
YP_RS11380	COG0719	Fe-S assembly protein
YP_RS11385	COG0316	Belongs to the HesB IscA family
YP_RS11395	COG2050	protein possibly involved in aromatic compounds catabolism
YP_RS11400	COG0247	lactate metabolic process
YP_RS11400	COG0277	FAD linked oxidase domain protein
YP_RS11405	COG0628	permease
YP_RS11410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YP_RS11410	COG0574	Belongs to the PEP-utilizing enzyme family
YP_RS11435	COG0791	NLP P60 protein
YP_RS11480	COG0386	Belongs to the glutathione peroxidase family
YP_RS11495	COG0776	regulation of translation
YP_RS11500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YP_RS11500	COG0072	phenylalanine-tRNA ligase activity
YP_RS11530	COG4249	Peptidase C14 caspase catalytic subunit p20
YP_RS11555	COG0803	Belongs to the bacterial solute-binding protein 9 family
YP_RS11560	COG1121	(ABC) transporter
YP_RS11565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YP_RS11570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YP_RS11580	COG3001	Fructosamine kinase
YP_RS11590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YP_RS11595	COG3328	transposase activity
YP_RS11610	COG1252	NADH dehydrogenase
YP_RS11620	COG1472	Belongs to the glycosyl hydrolase 3 family
YP_RS11635	COG5633	Lipoprotein
YP_RS11640	COG0537	adenosine 5'-monophosphoramidase activity
YP_RS11645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YP_RS11655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YP_RS11655	COG1263	PTS System
YP_RS11660	COG0084	hydrolase, TatD family'
YP_RS11665	COG0470	DNA polymerase III
YP_RS11675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YP_RS11680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YP_RS11690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YP_RS11720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YP_RS11725	COG1399	metal-binding, possibly nucleic acid-binding protein
YP_RS11730	COG0424	maF-like protein
YP_RS11735	COG0564	pseudouridine synthase activity
YP_RS11740	COG1530	ribonuclease E activity
YP_RS11745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YP_RS11770	COG3328	transposase activity
YP_RS11785	COG0628	permease
YP_RS11815	COG3916	Acyl-homoserine-lactone synthase
YP_RS11820	COG2771	luxR family
YP_RS11825	COG0583	DNA-binding transcription factor activity
YP_RS11835	COG0477	Major facilitator Superfamily
YP_RS11845	COG0667	Aldo Keto reductase
YP_RS11870	COG1203	CRISPR-associated helicase, Cas3
YP_RS11875	COG1518	maintenance of DNA repeat elements
YP_RS11885	COG0668	transmembrane transport
YP_RS11905	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YP_RS11910	COG0395	ABC-type sugar transport system, permease component
YP_RS11925	COG1609	Transcriptional regulator
YP_RS11935	COG3842	ATPase activity
YP_RS11945	COG3210	domain, Protein
YP_RS11965	COG3210	domain, Protein
YP_RS11970	COG2831	hemolysin activation secretion protein
YP_RS11975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YP_RS11980	COG4638	Rieske (2fe-2S)
YP_RS11985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YP_RS11995	COG0473	3-isopropylmalate dehydrogenase activity
YP_RS12000	COG0583	DNA-binding transcription factor activity
YP_RS12005	COG1609	Transcriptional regulator
YP_RS12010	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS12015	COG1129	ABC transporter
YP_RS12020	COG1879	ABC-type sugar transport system periplasmic component
YP_RS12025	COG1063	alcohol dehydrogenase
YP_RS12045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YP_RS12075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YP_RS12080	COG0765	amino acid transport
YP_RS12085	COG1126	abc transporter atp-binding protein
YP_RS12105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YP_RS12120	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YP_RS12135	COG1169	isochorismate synthase
YP_RS12145	COG4575	ribosome binding
YP_RS12160	COG0129	dihydroxy-acid dehydratase activity
YP_RS12175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YP_RS12185	COG1609	Transcriptional regulator
YP_RS12190	COG1649	PFAM Uncharacterised BCR, COG1649
YP_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS12200	COG3265	gluconokinase activity
YP_RS12205	COG2731	YhcH YjgK YiaL family protein
YP_RS12220	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YP_RS12225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YP_RS12235	COG0839	Belongs to the complex I subunit 6 family
YP_RS12250	COG1034	ATP synthesis coupled electron transport
YP_RS12270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YP_RS12280	COG0583	DNA-binding transcription factor activity
YP_RS12290	COG0436	Aminotransferase
YP_RS12305	COG0471	metal ion transport
YP_RS12305	COG0490	domain, Protein
YP_RS12310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YP_RS12335	COG0857	belongs to the CobB CobQ family
YP_RS12335	COG0280	phosphate acetyltransferase
YP_RS12340	COG1609	Transcriptional regulator
YP_RS12355	COG3037	sugar-specific permease SgaT UlaA
YP_RS12360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YP_RS12365	COG0622	Phosphoesterase
YP_RS12375	COG1090	epimerase
YP_RS12380	COG4598	ABC transporter
YP_RS12385	COG4160	amino acid transport
YP_RS12390	COG4215	(ABC) transporter
YP_RS12395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YP_RS12405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YP_RS12410	COG1286	toxin biosynthetic process
YP_RS12415	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YP_RS12420	COG0285	dihydrofolate synthase activity
YP_RS12430	COG0586	Pfam SNARE associated Golgi protein
YP_RS12440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YP_RS12460	COG0697	spore germination
YP_RS12475	COG1794	racemase activity, acting on amino acids and derivatives
YP_RS12480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YP_RS12495	COG3101	peptidyl-lysine hydroxylation
YP_RS12500	COG0730	response to heat
YP_RS12515	COG2890	protein-(glutamine-N5) methyltransferase activity
YP_RS12530	COG2062	phosphohistidine phosphatase, SixA
YP_RS12545	COG3691	Protein conserved in bacteria
YP_RS12560	COG4235	cytochrome complex assembly
YP_RS12560	COG3088	subunit of a heme lyase
YP_RS12565	COG4235	cytochrome complex assembly
YP_RS12565	COG3088	subunit of a heme lyase
YP_RS12570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YP_RS12575	COG1138	Cytochrome C-type biogenesis protein
YP_RS12585	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YP_RS12590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YP_RS12595	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YP_RS12615	COG1704	LemA family
YP_RS12625	COG2824	Alkylphosphonate utilization operon protein PhnA
YP_RS12635	COG3328	transposase activity
YP_RS12690	COG2113	Glycine betaine
YP_RS12695	COG4176	ABC-type proline glycine betaine transport system permease component
YP_RS12700	COG4175	Glycine betaine
YP_RS12705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YP_RS12735	COG3328	transposase activity
YP_RS12750	COG1278	Cold shock
YP_RS12755	COG0747	negative chemotaxis
YP_RS12765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YP_RS12770	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YP_RS12775	COG1124	(ABC) transporter
YP_RS12780	COG0831	urea catabolic process
YP_RS12805	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YP_RS12815	COG4413	Urea transporter
YP_RS12820	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YP_RS12835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YP_RS12845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YP_RS12855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YP_RS12860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YP_RS12865	COG1447	Phosphotransferase system cellobiose-specific component IIA
YP_RS12870	COG1917	Cupin 2, conserved barrel domain protein
YP_RS12870	COG2169	Transcriptional regulator
YP_RS12890	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YP_RS12895	COG0033	Phosphoglucomutase
YP_RS12915	COG0745	RESPONSE REGULATOR receiver
YP_RS12920	COG2205	protein histidine kinase activity
YP_RS12955	COG3272	Protein of unknown function (DUF1722)
YP_RS12965	COG5212	phosphodiesterase
YP_RS12970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YP_RS12980	COG1984	allophanate hydrolase subunit 2
YP_RS13030	COG0513	Belongs to the DEAD box helicase family
YP_RS13040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YP_RS13055	COG3026	antisigma factor binding
YP_RS13060	COG3086	response to oxidative stress
YP_RS13095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YP_RS13115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YP_RS13120	COG1737	Transcriptional regulator
YP_RS13135	COG1737	Transcriptional regulator
YP_RS13145	COG0560	Phosphoserine phosphatase
YP_RS13185	COG2205	protein histidine kinase activity
YP_RS13190	COG3170	Tfp pilus assembly protein FimV
YP_RS13195	COG2204	response regulator
YP_RS13200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YP_RS13200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YP_RS13205	COG0347	Belongs to the P(II) protein family
YP_RS13210	COG2188	Transcriptional regulator
YP_RS13215	COG2188	Transcriptional regulator
YP_RS13220	COG1017	nitric oxide dioxygenase activity
YP_RS13220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YP_RS13240	COG2814	Major facilitator Superfamily
YP_RS13245	COG3711	transcriptional antiterminator
YP_RS13250	COG3683	transport system, periplasmic component
YP_RS13255	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YP_RS13275	COG1104	cysteine desulfurase activity
YP_RS13280	COG0822	iron-sulfur transferase activity
YP_RS13295	COG0443	Heat shock 70 kDa protein
YP_RS13300	COG0633	Ferredoxin
YP_RS13305	COG2975	iron-sulfur cluster assembly
YP_RS13325	COG3468	outer membrane autotransporter barrel domain protein
YP_RS13330	COG3328	transposase activity
YP_RS13335	COG3188	usher protein
YP_RS13340	COG3121	Chaperone
YP_RS13400	COG2951	lytic endotransglycosylase activity
YP_RS13435	COG0243	molybdopterin cofactor binding
YP_RS13440	COG0437	4 iron, 4 sulfur cluster binding
YP_RS13445	COG3302	dmso reductase anchor subunit
YP_RS13450	COG3381	protein complex oligomerization
YP_RS13480	COG3038	cytochrome b561
YP_RS13485	COG0436	Aminotransferase
YP_RS13510	COG0667	Aldo Keto reductase
YP_RS13525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YP_RS13570	COG3530	Putative quorum-sensing-regulated virulence factor
YP_RS13585	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YP_RS13595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YP_RS13620	COG2205	protein histidine kinase activity
YP_RS13625	COG0745	RESPONSE REGULATOR receiver
YP_RS13630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YP_RS13645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YP_RS13665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YP_RS13675	COG5002	protein histidine kinase activity
YP_RS13675	COG3850	Histidine kinase
YP_RS13680	COG0745	RESPONSE REGULATOR receiver
YP_RS13695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YP_RS13700	COG4208	sulfate ABC transporter
YP_RS13705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YP_RS13710	COG4150	thiosulfate binding
YP_RS13720	COG1737	Transcriptional regulator
YP_RS13730	COG2731	YhcH YjgK YiaL family protein
YP_RS13740	COG4886	Leucine-rich repeat (LRR) protein
YP_RS13750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YP_RS13755	COG2837	iron assimilation
YP_RS13765	COG3111	PFAM Bacterial OB fold (BOF) protein
YP_RS13810	COG3005	denitrification pathway
YP_RS13815	COG3043	anaerobic respiration
YP_RS13825	COG3062	negative regulation of establishment of protein localization
YP_RS13830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YP_RS13830	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YP_RS13835	COG2197	response regulator
YP_RS13845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YP_RS13855	COG1988	membrane-bound metal-dependent
YP_RS13860	COG3119	arylsulfatase activity
YP_RS13870	COG3842	ATPase activity
YP_RS13890	COG1393	Belongs to the ArsC family
YP_RS13900	COG1876	peptidase activity
YP_RS13920	COG2321	neutral zinc metallopeptidase
YP_RS13940	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YP_RS13950	COG2716	regulation of RNA biosynthetic process
YP_RS13955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YP_RS13975	COG0628	permease
YP_RS13980	COG4783	chaperone-mediated protein folding
YP_RS13985	COG1393	Belongs to the ArsC family
YP_RS14010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YP_RS14015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YP_RS14035	COG0581	inorganic phosphate transmembrane transporter activity
YP_RS14045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YP_RS14060	COG2239	Acts as a magnesium transporter
YP_RS14065	COG0443	Heat shock 70 kDa protein
YP_RS14070	COG1177	transmembrane transport
YP_RS14075	COG1176	ABC-type spermidine putrescine transport system, permease component I
YP_RS14085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YP_RS14095	COG3842	ATPase activity
YP_RS14120	COG2205	protein histidine kinase activity
YP_RS14125	COG0745	RESPONSE REGULATOR receiver
YP_RS14130	COG3422	double-strand break repair
YP_RS14135	COG0826	peptidase U32
YP_RS14155	COG0351	phosphomethylpyrimidine kinase
YP_RS14170	COG3328	transposase activity
YP_RS14225	COG0517	IMP dehydrogenase activity
YP_RS14225	COG0516	GMP reductase activity
YP_RS14235	COG1645	bacterial-type flagellum-dependent swarming motility
YP_RS14250	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YP_RS14255	COG2976	Protein conserved in bacteria
YP_RS14300	COG3468	outer membrane autotransporter barrel domain protein
YP_RS14310	COG3328	transposase activity
YP_RS14315	COG3188	usher protein
YP_RS14375	COG1953	Uracil, thiamine, allantoin
YP_RS14395	COG2226	methyltransferase
YP_RS14400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YP_RS14405	COG1388	LysM domain
YP_RS14405	COG0741	lytic transglycosylase activity
YP_RS14420	COG0656	L-ascorbic acid biosynthetic process
YP_RS14455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YP_RS14465	COG2011	ABC-type metal ion transport system permease component
YP_RS14470	COG1464	Belongs to the NlpA lipoprotein family
YP_RS14480	COG1720	tRNA m6t6A37 methyltransferase activity
YP_RS14490	COG3015	lipoprotein NlpE involved in copper resistance
YP_RS14500	COG4681	YaeQ
YP_RS14510	COG4568	rho-dependent transcription termination
YP_RS14520	COG0037	tRNA processing
YP_RS14525	COG0346	lactoylglutathione lyase activity
YP_RS14535	COG0587	DNA-directed DNA polymerase activity
YP_RS14560	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YP_RS14575	COG0750	zinc metalloprotease
YP_RS14580	COG0575	Belongs to the CDS family
YP_RS14640	COG0564	pseudouridine synthase activity
YP_RS14645	COG3098	single-species biofilm formation
YP_RS14665	COG1611	Belongs to the LOG family
YP_RS14680	COG2363	Small membrane protein
YP_RS14685	COG0583	DNA-binding transcription factor activity
YP_RS14690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YP_RS14695	COG2166	iron-sulfur cluster assembly
YP_RS14700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YP_RS14705	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YP_RS14720	COG0860	N-Acetylmuramoyl-L-alanine amidase
YP_RS14765	COG0288	reversible hydration of carbon dioxide
YP_RS14785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YP_RS14845	COG3328	transposase activity
YP_RS14860	COG0840	transmembrane signaling receptor activity
YP_RS14875	COG0583	DNA-binding transcription factor activity
YP_RS14880	COG2814	Major facilitator Superfamily
YP_RS14885	COG0583	DNA-binding transcription factor activity
YP_RS14895	COG1609	Transcriptional regulator
YP_RS14925	COG0667	Aldo Keto reductase
YP_RS14990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YP_RS15000	COG1074	ATP-dependent DNA helicase activity
YP_RS15005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YP_RS15020	COG0435	Glutathione S-transferase
YP_RS15025	COG2259	Doxx family
YP_RS15035	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YP_RS15040	COG4575	ribosome binding
YP_RS15060	COG0586	Pfam SNARE associated Golgi protein
YP_RS15075	COG2271	Major facilitator Superfamily
YP_RS15095	COG2721	sulfolactate sulfo-lyase activity
YP_RS15115	COG0673	inositol 2-dehydrogenase activity
YP_RS15120	COG1451	nucleotide metabolic process
YP_RS15135	COG0446	pyridine nucleotide-disulphide oxidoreductase
YP_RS15135	COG1902	pentaerythritol trinitrate reductase activity
YP_RS15140	COG3247	response to pH
YP_RS15160	COG4245	von Willebrand factor, type A
YP_RS15175	COG4245	von Willebrand factor, type A
YP_RS15180	COG2831	hemolysin activation secretion protein
YP_RS15185	COG3210	domain, Protein
YP_RS15210	COG3210	domain, Protein
YP_RS15215	COG3210	domain, Protein
YP_RS15235	COG3842	ATPase activity
YP_RS15240	COG3459	Glycosyltransferase 36 associated
YP_RS15245	COG1609	Transcriptional regulator
YP_RS15250	COG2182	Extracellular solute-binding protein
YP_RS15260	COG0395	ABC-type sugar transport system, permease component
YP_RS15280	COG1289	transmembrane transporter activity
YP_RS15305	COG0436	Aminotransferase
YP_RS15325	COG0251	oxidation-reduction process
YP_RS15395	COG3328	transposase activity
YP_RS15420	COG0358	DNA primase activity
YP_RS15425	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YP_RS15440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YP_RS15455	COG4991	sh3 domain protein
YP_RS15460	COG3025	triphosphatase activity
YP_RS15475	COG0531	amino acid
YP_RS15495	COG3384	dioxygenase
YP_RS15500	COG0754	glutathionylspermidine amidase activity
YP_RS15515	COG1538	Outer membrane efflux protein
YP_RS15520	COG0494	nUDIX hydrolase
YP_RS15525	COG3151	Protein conserved in bacteria
YP_RS15530	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YP_RS15535	COG3150	esterase
YP_RS15545	COG0583	DNA-binding transcription factor activity
YP_RS15550	COG2249	NAD(P)H dehydrogenase (quinone) activity
YP_RS15555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YP_RS15565	COG2132	Multicopper oxidase
YP_RS15575	COG0656	L-ascorbic acid biosynthetic process
YP_RS15585	COG1979	alcohol dehydrogenase
YP_RS15590	COG2207	Transcriptional regulator
YP_RS15595	COG0586	Pfam SNARE associated Golgi protein
YP_RS15600	COG0626	cystathionine gamma-synthase activity
YP_RS15605	COG0811	peptide transport
YP_RS15610	COG0848	biopolymer transport protein
YP_RS15660	COG4964	Belongs to the GSP D family
YP_RS15665	COG4964	Belongs to the GSP D family
YP_RS15700	COG4592	Periplasmic binding protein
YP_RS15720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YP_RS15725	COG1684	flagellar biosynthetic protein fliR
YP_RS15730	COG1987	bacterial-type flagellum assembly
YP_RS15755	COG1677	Flagellar hook-basal body complex protein FliE
YP_RS15795	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YP_RS15800	COG1815	bacterial-type flagellum-dependent cell motility
YP_RS15805	COG1558	bacterial-type flagellum-dependent cell motility
YP_RS15810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YP_RS15815	COG1749	Flagellar hook protein flgE
YP_RS15820	COG4787	bacterial-type flagellum-dependent cell motility
YP_RS15825	COG4786	Flagellar basal body rod
YP_RS15835	COG1706	bacterial-type flagellum-dependent cell motility
YP_RS15845	COG1256	bacterial-type flagellum assembly
YP_RS15865	COG3710	Transcriptional regulator
YP_RS15875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YP_RS15900	COG1191	sigma factor activity
YP_RS15905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YP_RS15950	COG2801	Transposase and inactivated derivatives
YP_RS16010	COG1175	transmembrane transport
YP_RS16015	COG3833	ABC-type maltose transport systems, permease component
YP_RS16030	COG0527	aspartate kinase activity
YP_RS16055	COG1414	Transcriptional regulator
YP_RS16065	COG2224	Isocitrate lyase
YP_RS16070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YP_RS16130	COG0151	Belongs to the GarS family
YP_RS16150	COG1515	deoxyribonuclease V activity
YP_RS16190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YP_RS16245	COG0250	Participates in transcription elongation, termination and antitermination
YP_RS16280	COG2801	Transposase and inactivated derivatives
YP_RS16300	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YP_RS16320	COG1629	transport
YP_RS16345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YP_RS16350	COG0678	peroxiredoxin activity
YP_RS16350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YP_RS16430	COG1879	ABC-type sugar transport system periplasmic component
YP_RS16435	COG1129	ABC transporter
YP_RS16440	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS16445	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS16455	COG3085	chromosome segregation
YP_RS16470	COG3978	acetolactate synthase activity
YP_RS16475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YP_RS16515	COG0583	DNA-binding transcription factor activity
YP_RS16555	COG3121	Chaperone
YP_RS16570	COG3121	Chaperone
YP_RS16590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YP_RS16615	COG3118	belongs to the thioredoxin family
YP_RS16620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YP_RS16625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_RS16630	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YP_RS16635	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YP_RS16640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YP_RS16645	COG1088	dTDP-glucose 4,6-dehydratase activity
YP_RS16650	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YP_RS16655	COG0456	acetyltransferase
YP_RS16660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YP_RS16665	COG2244	polysaccharide biosynthetic process
YP_RS16685	COG1113	amino acid transport
YP_RS16715	COG3071	HemY protein
YP_RS16720	COG2959	enzyme of heme biosynthesis
YP_RS16725	COG1587	Uroporphyrinogen-III synthase
YP_RS16735	COG3072	Adenylate cyclase
YP_RS16755	COG3159	Protein conserved in bacteria
YP_RS16760	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YP_RS16765	COG1011	Hydrolase
YP_RS16770	COG0210	DNA helicase
YP_RS16780	COG5441	Belongs to the UPF0261 family
YP_RS16785	COG5564	TIM-barrel signal transduction protein
YP_RS16800	COG2050	protein possibly involved in aromatic compounds catabolism
YP_RS16805	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YP_RS16810	COG0514	ATP-dependent DNA helicase (RecQ)
YP_RS16815	COG1280	lysine exporter protein (LysE YggA)
YP_RS16820	COG1280	lysine exporter protein (LysE YggA)
YP_RS16825	COG2267	carboxylic ester hydrolase activity
YP_RS16830	COG0561	phosphatase activity
YP_RS16840	COG0584	glycerophosphoryl diester phosphodiesterase
YP_RS16850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YP_RS16860	COG0247	lactate metabolic process
YP_RS16870	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YP_RS16885	COG3714	YhhN family
YP_RS16900	COG3776	membrane
YP_RS16905	COG0742	ribosomal rna small subunit methyltransferase
YP_RS16915	COG0552	protein localization to endoplasmic reticulum
YP_RS16915	COG0552	protein localization to endoplasmic reticulum
YP_RS16920	COG2884	Cell division ATP-binding protein ftsE
YP_RS16925	COG2177	Part of the ABC transporter FtsEX involved in
YP_RS16950	COG0683	leucine binding
YP_RS16960	COG4177	L-phenylalanine transmembrane transporter activity
YP_RS16970	COG0410	ABC transporter
YP_RS17030	COG0584	glycerophosphoryl diester phosphodiesterase
YP_RS17035	COG0679	Auxin Efflux Carrier
YP_RS17040	COG0697	spore germination
YP_RS17045	COG0583	DNA-binding transcription factor activity
YP_RS17055	COG0412	Dienelactone hydrolase
YP_RS17070	COG1966	Carbon starvation protein
YP_RS17075	COG0586	Pfam SNARE associated Golgi protein
YP_RS17080	COG1322	Protein conserved in bacteria
YP_RS17100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YP_RS17110	COG0805	protein transport
YP_RS17145	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YP_RS17170	COG1739	Uncharacterized protein family UPF0029
YP_RS17175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YP_RS17180	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YP_RS17210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YP_RS17240	COG2801	Transposase and inactivated derivatives
YP_RS17260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YP_RS17265	COG0058	SHG alpha-glucan phosphorylase activity
YP_RS17290	COG3275	phosphorelay sensor kinase activity
YP_RS17320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YP_RS17325	COG2095	MarC family integral membrane protein
YP_RS17345	COG3265	gluconokinase activity
YP_RS17350	COG2610	gluconate transmembrane transporter activity
YP_RS17355	COG1609	Transcriptional regulator
YP_RS17360	COG1741	Belongs to the pirin family
YP_RS17380	COG0191	fructose-bisphosphate aldolase activity
YP_RS17395	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS17410	COG2081	HI0933 family
YP_RS17415	COG0306	phosphate transporter
YP_RS17430	COG0589	response to stress
YP_RS17450	COG0339	signal peptide processing
YP_RS17455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YP_RS17460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YP_RS17465	COG3835	regulator
YP_RS17470	COG2610	gluconate transmembrane transporter activity
YP_RS17475	COG1929	Belongs to the glycerate kinase type-1 family
YP_RS17500	COG1295	ribonuclease BN
YP_RS17505	COG2134	cdp-diacylglycerol pyrophosphatase
YP_RS17510	COG2982	Protein involved in outer membrane biogenesis
YP_RS17515	COG2200	EAL domain
YP_RS17520	COG1942	4-Oxalocrotonate Tautomerase
YP_RS17525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YP_RS17530	COG0612	Peptidase, M16
YP_RS17550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YP_RS17555	COG2200	EAL domain
YP_RS17555	COG2199	diguanylate cyclase activity
YP_RS17560	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YP_RS17565	COG4608	Belongs to the ABC transporter superfamily
YP_RS17570	COG0444	Belongs to the ABC transporter superfamily
YP_RS17575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YP_RS17580	COG0601	transmembrane transport
YP_RS17585	COG0747	negative chemotaxis
YP_RS17595	COG2831	hemolysin activation secretion protein
YP_RS17610	COG2271	Major facilitator Superfamily
YP_RS17615	COG3851	Histidine kinase
YP_RS17620	COG2197	response regulator
YP_RS17625	COG2194	sulfuric ester hydrolase activity
YP_RS17650	COG2986	histidine ammonia-lyase
YP_RS17680	COG4607	ABC-type enterochelin transport system periplasmic component
YP_RS17690	COG4605	iron ion homeostasis
YP_RS17695	COG4604	ABC transporter, ATP-binding protein
YP_RS17735	COG0582	viral genome integration into host DNA
YP_RS17740	COG1609	Transcriptional regulator
YP_RS17740	COG2207	Transcriptional regulator
YP_RS17745	COG4214	carbohydrate transport
YP_RS17755	COG4213	ABC transporter substrate-binding protein
YP_RS17765	COG1070	Carbohydrate kinase
YP_RS17775	COG3121	Chaperone
YP_RS17795	COG3274	enterobacterial common antigen metabolic process
YP_RS17810	COG2801	Transposase and inactivated derivatives
YP_RS17815	COG5001	Diguanylate cyclase
YP_RS17820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YP_RS17860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YP_RS17865	COG2195	Cleaves the N-terminal amino acid of tripeptides
YP_RS17870	COG4771	TonB-dependent receptor
YP_RS17880	COG3433	isochorismatase activity
YP_RS17880	COG2226	methyltransferase
YP_RS17880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YP_RS17890	COG2226	methyltransferase
YP_RS17890	COG3433	isochorismatase activity
YP_RS17890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YP_RS17915	COG2375	cellular response to nickel ion
YP_RS17915	COG1132	(ABC) transporter
YP_RS17920	COG1132	(ABC) transporter
YP_RS17935	COG2610	gluconate transmembrane transporter activity
YP_RS17955	COG3501	Rhs element vgr protein
YP_RS17965	COG3209	COG3209 Rhs family protein
YP_RS17980	COG0471	metal ion transport
YP_RS17995	COG2211	Major facilitator Superfamily
YP_RS18045	COG2771	luxR family
YP_RS18050	COG3916	Acyl-homoserine-lactone synthase
YP_RS18185	COG1982	Orn Lys Arg decarboxylase major
YP_RS18190	COG1879	ABC-type sugar transport system periplasmic component
YP_RS18195	COG1129	ABC transporter
YP_RS18200	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS18205	COG4774	siderophore transport
YP_RS18225	COG1194	a g-specific adenine glycosylase
YP_RS18235	COG3171	Protein conserved in bacteria
YP_RS18255	COG3064	Membrane
YP_RS18255	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YP_RS18255	COG1073	alpha beta
YP_RS18260	COG3328	transposase activity
YP_RS18265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YP_RS18270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YP_RS18280	COG0762	integral membrane protein
YP_RS18285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YP_RS18290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YP_RS18295	COG2805	Type II/IV secretion system protein
YP_RS18305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YP_RS18320	COG0189	ligase activity
YP_RS18325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YP_RS18330	COG2356	endonuclease I
YP_RS18345	COG1166	arginine decarboxylase activity
YP_RS18355	COG0501	Belongs to the peptidase M48B family
YP_RS18360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YP_RS18380	COG0191	fructose-bisphosphate aldolase activity
YP_RS18415	COG3119	arylsulfatase activity
YP_RS18420	COG1349	DNA-binding transcription factor activity
YP_RS18430	COG2222	sugar isomerase
YP_RS18435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YP_RS18440	COG3715	PTS system
YP_RS18445	COG3716	PTS system mannose fructose sorbose family IID component
YP_RS18450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YP_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
YP_RS18470	COG0641	radical SAM
YP_RS18475	COG3119	arylsulfatase activity
YP_RS18505	COG2271	Major facilitator Superfamily
YP_RS18525	COG1263	PTS System
YP_RS18525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YP_RS18530	COG1874	Beta-galactosidase
YP_RS18535	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YP_RS18540	COG3833	ABC-type maltose transport systems, permease component
YP_RS18545	COG1175	transmembrane transport
YP_RS18550	COG2182	Extracellular solute-binding protein
YP_RS18560	COG1129	ABC transporter
YP_RS18565	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS18570	COG1879	ABC-type sugar transport system periplasmic component
YP_RS18580	COG0791	NLP P60 protein
YP_RS18585	COG1695	Transcriptional regulator
YP_RS18680	COG2944	sequence-specific DNA binding
YP_RS18710	COG0582	viral genome integration into host DNA
YP_RS18730	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YP_RS18735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YP_RS18740	COG4974	Belongs to the 'phage' integrase family
YP_RS18745	COG0716	FMN binding
YP_RS18750	COG4452	Inner membrane protein CreD
YP_RS18755	COG2205	protein histidine kinase activity
YP_RS18760	COG0745	RESPONSE REGULATOR receiver
YP_RS18785	COG1272	protein, Hemolysin III
YP_RS18795	COG5295	Hep Hag repeat protein
YP_RS18825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YP_RS18830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YP_RS18835	COG0006	proline dipeptidase activity
YP_RS18850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YP_RS18855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YP_RS18890	COG0494	nUDIX hydrolase
YP_RS18915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YP_RS18920	COG0849	cell division
YP_RS18925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YP_RS18945	COG0772	Belongs to the SEDS family
YP_RS18960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YP_RS18965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YP_RS18970	COG0768	penicillin binding
YP_RS18975	COG3116	cell division
YP_RS18995	COG1609	Transcriptional regulator
YP_RS19030	COG1022	Amp-dependent synthetase and ligase
YP_RS19040	COG0028	Belongs to the TPP enzyme family
YP_RS19060	COG0473	3-isopropylmalate dehydrogenase activity
YP_RS19075	COG2814	Major facilitator Superfamily
YP_RS19095	COG4143	(ABC) transporter
YP_RS19100	COG1178	ABC-type Fe3 transport system permease component
YP_RS19105	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
YP_RS19110	COG0586	Pfam SNARE associated Golgi protein
YP_RS19115	COG0417	DNA replication proofreading
YP_RS19135	COG2885	chlorophyll binding
YP_RS19135	COG3047	cAMP biosynthetic process
YP_RS19220	COG0564	pseudouridine synthase activity
YP_RS19225	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YP_RS19275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YP_RS19285	COG2966	Psort location CytoplasmicMembrane, score
YP_RS19290	COG1280	lysine exporter protein (LysE YggA)
YP_RS19295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YP_RS19330	COG1047	Peptidyl-prolyl cis-trans
YP_RS19345	COG0196	riboflavin kinase activity
YP_RS19360	COG0583	DNA-binding transcription factor activity
YP_RS19395	COG0521	Mo-molybdopterin cofactor biosynthetic process
YP_RS19425	COG0745	RESPONSE REGULATOR receiver
YP_RS19430	COG3045	CreA protein
YP_RS19435	COG3708	Transcriptional regulator
YP_RS19435	COG2207	Transcriptional regulator
YP_RS19450	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YP_RS19455	COG0741	lytic transglycosylase activity
YP_RS19470	COG2199	diguanylate cyclase activity
YP_RS19475	COG2885	chlorophyll binding
YP_RS19480	COG0488	(ABC) transporter
YP_RS19500	COG0560	Phosphoserine phosphatase
YP_RS19505	COG3726	membrane protein affecting hemolysin expression
YP_RS19530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YP_RS19535	COG0084	hydrolase, TatD family'
YP_RS19540	COG4667	esterase of the alpha-beta hydrolase superfamily
YP_RS19550	COG2823	Periplasmic or secreted lipoprotein
YP_RS19560	COG0456	acetyltransferase
YP_RS19565	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YP_RS19610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YP_RS19615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YP_RS19635	COG0859	PFAM glycosyl transferase family 9
YP_RS19645	COG2390	Transcriptional regulator
YP_RS19690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YP_RS19690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YP_RS19690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YP_RS19695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YP_RS19700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YP_RS19705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YP_RS19710	COG2207	Transcriptional regulator
YP_RS19720	COG4269	membrane
YP_RS19770	COG2963	transposase activity
YP_RS19785	COG1401	restriction endodeoxyribonuclease activity
YP_RS19800	COG0435	Glutathione S-transferase
YP_RS19805	COG0583	DNA-binding transcription factor activity
YP_RS19810	COG1741	Belongs to the pirin family
YP_RS19815	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YP_RS19835	COG2823	Periplasmic or secreted lipoprotein
YP_RS19845	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YP_RS19855	COG2198	Histidine kinase
YP_RS19855	COG0784	Response regulator, receiver
YP_RS19855	COG5002	protein histidine kinase activity
YP_RS19865	COG1242	4 iron, 4 sulfur cluster binding
YP_RS19870	COG0070	glutamate synthase
YP_RS19870	COG0069	glutamate synthase activity
YP_RS19870	COG0067	glutamate synthase
YP_RS19875	COG0493	'glutamate synthase
YP_RS19885	COG2969	positive regulation of protein catabolic process
YP_RS19890	COG0625	glutathione transferase activity
YP_RS19910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YP_RS19915	COG3105	Protein conserved in bacteria
YP_RS19920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YP_RS19930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YP_RS19940	COG5007	Belongs to the BolA IbaG family
YP_RS19945	COG3113	response to antibiotic
YP_RS19950	COG2854	intermembrane phospholipid transfer
YP_RS19955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YP_RS19960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YP_RS19965	COG1127	ABC transporter
YP_RS19970	COG0530	calcium, potassium:sodium antiporter activity
YP_RS19975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YP_RS19975	COG0517	IMP dehydrogenase activity
YP_RS19980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YP_RS19985	COG3117	lipopolysaccharide transmembrane transporter activity
YP_RS19990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YP_RS19995	COG1137	ATPase activity
YP_RS20000	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YP_RS20020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YP_RS20045	COG1609	Transcriptional regulator
YP_RS20050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YP_RS20050	COG1263	PTS System
YP_RS20055	COG0366	Alpha amylase catalytic
YP_RS20060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_RS20065	COG3783	Cytochrome b(562)
YP_RS20075	COG0312	modulator of DNA gyrase
YP_RS20085	COG2732	(Barnase) inhibitor
YP_RS20100	COG1012	belongs to the aldehyde dehydrogenase family
YP_RS20120	COG0583	DNA-binding transcription factor activity
YP_RS20175	COG0312	modulator of DNA gyrase
YP_RS20180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YP_RS20185	COG3164	Protein of unknown function
YP_RS20190	COG1530	ribonuclease E activity
YP_RS20195	COG0424	maF-like protein
YP_RS20200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YP_RS20205	COG1792	Involved in formation and maintenance of cell shape
YP_RS20210	COG1077	Cell shape determining protein MreB Mrl
YP_RS20215	COG2199	diguanylate cyclase activity
YP_RS20215	COG2200	EAL domain
YP_RS20220	COG0604	alcohol dehydrogenase
YP_RS20225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YP_RS20240	COG0511	ligase activity, forming carbon-carbon bonds
YP_RS20245	COG0439	Biotin carboxylase
YP_RS20250	COG3924	membrane
YP_RS20255	COG4145	pantothenate transmembrane transporter activity
YP_RS20265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YP_RS20270	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YP_RS20290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YP_RS20300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YP_RS20305	COG3133	Outer membrane lipoprotein
YP_RS20315	COG1278	Cold shock
YP_RS20320	COG1278	Cold shock
YP_RS20345	COG0625	glutathione transferase activity
YP_RS20355	COG1069	ribulokinase activity
YP_RS20365	COG1172	Belongs to the binding-protein-dependent transport system permease family
YP_RS20370	COG1129	ABC transporter
YP_RS20380	COG1560	Kdo2-lipid A biosynthetic process
YP_RS20390	COG0025	NhaP-type Na H and K H
YP_RS20395	COG2252	PERMEase
YP_RS20400	COG3077	Addiction module antitoxin, RelB DinJ family
YP_RS20410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YP_RS20425	COG0431	NADPH-dependent FMN reductase
YP_RS20430	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YP_RS20435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YP_RS20440	COG1869	D-ribose catabolic process
YP_RS20445	COG1917	Cupin 2, conserved barrel domain protein
YP_RS20445	COG2207	Transcriptional regulator
YP_RS20450	COG0673	inositol 2-dehydrogenase activity
YP_RS20460	COG3328	transposase activity
YP_RS20470	COG3209	COG3209 Rhs family protein
YP_RS20480	COG3501	Rhs element vgr protein
YP_RS20525	COG3501	Rhs element vgr protein
YP_RS20600	COG2801	Transposase and inactivated derivatives
YP_RS20635	COG3276	selenocysteine insertion sequence binding
YP_RS20640	COG3276	selenocysteine insertion sequence binding
YP_RS20655	COG2864	formate dehydrogenase
YP_RS20660	COG0437	4 iron, 4 sulfur cluster binding
YP_RS20665	COG3383	formate dehydrogenase (NAD+) activity
YP_RS20665	COG0243	molybdopterin cofactor binding
YP_RS20670	COG3383	formate dehydrogenase (NAD+) activity
YP_RS20670	COG0243	molybdopterin cofactor binding
YP_RS20680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YP_RS20705	COG3722	fumarate hydratase activity
YP_RS20715	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YP_RS20715	COG2213	PTS system mannitol-specific
YP_RS20735	COG2818	Glycosylase
YP_RS20745	COG2885	chlorophyll binding
YP_RS20760	COG0366	Alpha amylase catalytic
YP_RS20770	COG3977	Valine--pyruvate aminotransferase
YP_RS20790	COG5645	(Lipo)protein
YP_RS20795	COG0823	Involved in the tonB-independent uptake of proteins
YP_RS20800	COG0823	Involved in the tonB-independent uptake of proteins
YP_RS20805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YP_RS20810	COG2423	ornithine cyclodeaminase activity
YP_RS20820	COG2801	Transposase and inactivated derivatives
YP_RS20825	COG0561	phosphatase activity
YP_RS20830	COG0187	DNA topoisomerase II activity
YP_RS20845	COG0592	DNA-directed DNA polymerase activity
YP_RS20855	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YP_RS20865	COG0706	membrane insertase activity
YP_RS20890	COG2252	PERMEase
YP_RS20895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YP_RS20900	COG0765	amino acid transport
YP_RS20905	COG0765	amino acid transport
YP_RS20910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YP_RS20920	COG0704	Plays a role in the regulation of phosphate uptake
YP_RS20930	COG0581	inorganic phosphate transmembrane transporter activity
YP_RS20935	COG0573	inorganic phosphate transmembrane transporter activity
YP_RS20940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YP_RS20995	COG3312	ion transport
YP_RS21050	COG3158	transport of potassium into the cell
YP_RS21245	COG1011	Hydrolase
YP_RS21370	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YP_RS21850	COG2982	Protein involved in outer membrane biogenesis
YP_RS21885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YP_RS21890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YP_RS21935	COG2860	membrane
YP_RS22025	COG4942	peptidase