locus-tag	class	description
CH60_RS00060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH60_RS00215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH60_RS00220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH60_RS00285	COG1295	ribonuclease BN
CH60_RS00335	COG0612	Peptidase, M16
CH60_RS00340	COG0612	Peptidase, M16
CH60_RS00565	COG1640	4-alpha-glucanotransferase
CH60_RS01015	COG2200	EAL domain
CH60_RS01015	COG2199	diguanylate cyclase activity
CH60_RS01090	COG2271	Major facilitator Superfamily
CH60_RS01150	COG0191	fructose-bisphosphate aldolase activity
CH60_RS01165	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS01180	COG2081	HI0933 family
CH60_RS01185	COG0306	phosphate transporter
CH60_RS01200	COG0589	response to stress
CH60_RS01220	COG0339	signal peptide processing
CH60_RS01225	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH60_RS01230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH60_RS01235	COG3835	regulator
CH60_RS01240	COG2610	gluconate transmembrane transporter activity
CH60_RS01245	COG1929	Belongs to the glycerate kinase type-1 family
CH60_RS01270	COG1295	ribonuclease BN
CH60_RS01275	COG2134	cdp-diacylglycerol pyrophosphatase
CH60_RS01280	COG2982	Protein involved in outer membrane biogenesis
CH60_RS01285	COG2200	EAL domain
CH60_RS01290	COG1942	4-Oxalocrotonate Tautomerase
CH60_RS01295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH60_RS01300	COG0612	Peptidase, M16
CH60_RS01320	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH60_RS01325	COG2199	diguanylate cyclase activity
CH60_RS01325	COG2200	EAL domain
CH60_RS01330	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH60_RS01335	COG4608	Belongs to the ABC transporter superfamily
CH60_RS01340	COG0444	Belongs to the ABC transporter superfamily
CH60_RS01345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH60_RS01350	COG0601	transmembrane transport
CH60_RS01355	COG0747	negative chemotaxis
CH60_RS01365	COG2831	hemolysin activation secretion protein
CH60_RS01380	COG2271	Major facilitator Superfamily
CH60_RS01385	COG3851	Histidine kinase
CH60_RS01390	COG2197	response regulator
CH60_RS01395	COG2194	sulfuric ester hydrolase activity
CH60_RS01420	COG2801	Transposase and inactivated derivatives
CH60_RS01430	COG1349	DNA-binding transcription factor activity
CH60_RS01450	COG0058	SHG alpha-glucan phosphorylase activity
CH60_RS01460	COG1640	4-alpha-glucanotransferase
CH60_RS01495	COG1918	ferrous iron import across plasma membrane
CH60_RS01505	COG2183	response to ionizing radiation
CH60_RS01510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH60_RS01535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH60_RS01540	COG1011	Hydrolase
CH60_RS01555	COG0494	nUDIX hydrolase
CH60_RS01560	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH60_RS01590	COG4796	Type ii and iii secretion system protein
CH60_RS01615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH60_RS01620	COG0546	phosphoglycolate phosphatase activity
CH60_RS01625	COG0180	Tryptophanyl-tRNA synthetase
CH60_RS01645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH60_RS01650	COG0402	S-adenosylhomocysteine deaminase activity
CH60_RS01670	COG1486	melibiose metabolic process
CH60_RS01675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH60_RS01680	COG0433	COG0433 Predicted ATPase
CH60_RS01695	COG1289	transmembrane transporter activity
CH60_RS01705	COG1765	OsmC-like protein
CH60_RS01715	COG3954	Phosphoribulokinase
CH60_RS01725	COG0429	hydrolase of the alpha beta-hydrolase fold
CH60_RS01735	COG4521	taurine ABC transporter
CH60_RS01745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH60_RS01750	COG2175	clavaminate synthase activity
CH60_RS01760	COG1216	Glycosyl transferase, family 2
CH60_RS01765	COG0488	(ABC) transporter
CH60_RS01780	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH60_RS01785	COG1047	Peptidyl-prolyl cis-trans
CH60_RS01795	COG0545	Peptidyl-prolyl cis-trans isomerase
CH60_RS01800	COG2964	Protein conserved in bacteria
CH60_RS01820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH60_RS01825	COG0049	tRNA binding
CH60_RS01855	COG0051	transcription antitermination factor activity, RNA binding
CH60_RS01870	COG0089	rRNA binding
CH60_RS01880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH60_RS01890	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH60_RS01895	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH60_RS01905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH60_RS01910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH60_RS01950	COG1841	ribosomal large subunit assembly
CH60_RS01960	COG0201	protein transport
CH60_RS01965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH60_RS01980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH60_RS01995	COG0789	Transcriptional regulator
CH60_RS02000	COG3036	rescue of stalled ribosome
CH60_RS02030	COG0758	DNA mediated transformation
CH60_RS02040	COG0551	DNA topoisomerase type I activity
CH60_RS02055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH60_RS02125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH60_RS02135	COG0360	Binds together with S18 to 16S ribosomal RNA
CH60_RS02145	COG1073	alpha beta
CH60_RS02150	COG3650	response to hydrogen peroxide
CH60_RS02155	COG1960	acyl-CoA dehydrogenase activity
CH60_RS02160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH60_RS02165	COG0557	exoribonuclease II activity
CH60_RS02180	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH60_RS02185	COG0330	HflC and HflK could
CH60_RS02190	COG0330	HflC and HflK could
CH60_RS02195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH60_RS02215	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH60_RS02220	COG0802	atpase or kinase
CH60_RS02225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH60_RS02225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH60_RS02230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH60_RS02250	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH60_RS02270	COG3264	Mechanosensitive ion channel
CH60_RS02270	COG1511	domain protein
CH60_RS02285	COG1053	succinate dehydrogenase
CH60_RS02290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH60_RS02300	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH60_RS02345	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH60_RS02360	COG3383	formate dehydrogenase (NAD+) activity
CH60_RS02365	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH60_RS02370	COG0493	'glutamate synthase
CH60_RS02370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH60_RS02375	COG1309	transcriptional regulator
CH60_RS02445	COG1454	alcohol dehydrogenase
CH60_RS02455	COG0629	single-stranded DNA binding
CH60_RS02460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH60_RS02465	COG2315	Protein conserved in bacteria
CH60_RS02470	COG1448	Aminotransferase
CH60_RS02495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH60_RS02500	COG0735	belongs to the Fur family
CH60_RS02510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH60_RS02555	COG3121	Chaperone
CH60_RS02615	COG1358	cellular component organization or biogenesis
CH60_RS02640	COG3721	Heme iron utilization protein
CH60_RS02645	COG0702	epimerase
CH60_RS02655	COG4771	TonB-dependent receptor
CH60_RS02660	COG3720	iron ion transport
CH60_RS02665	COG4558	Periplasmic binding protein
CH60_RS02670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH60_RS02680	COG0626	cystathionine gamma-synthase activity
CH60_RS02685	COG0814	amino acid
CH60_RS02690	COG0583	DNA-binding transcription factor activity
CH60_RS02695	COG0425	Belongs to the sulfur carrier protein TusA family
CH60_RS02700	COG2391	methyltransferase activity
CH60_RS02810	COG1301	dicarboxylic acid transport
CH60_RS02820	COG3162	membrane
CH60_RS02850	COG0077	Prephenate dehydratase
CH60_RS02850	COG1605	Chorismate mutase
CH60_RS02855	COG0287	Prephenate dehydrogenase
CH60_RS02855	COG1605	Chorismate mutase
CH60_RS02860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH60_RS02865	COG3279	Response regulator of the LytR AlgR family
CH60_RS02875	COG3137	Salt-induced outer membrane protein
CH60_RS02900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH60_RS02905	COG4137	Cytochrome C assembly protein
CH60_RS02910	COG4536	flavin adenine dinucleotide binding
CH60_RS02920	COG2918	glutathione biosynthetic process
CH60_RS02925	COG1238	metal cluster binding
CH60_RS02930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH60_RS02955	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH60_RS02995	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH60_RS03000	COG3958	Transketolase
CH60_RS03005	COG3959	Transketolase, thiamine diphosphate binding domain
CH60_RS03010	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS03015	COG1129	ABC transporter
CH60_RS03025	COG1879	ABC-type sugar transport system periplasmic component
CH60_RS03035	COG3783	Cytochrome b(562)
CH60_RS03040	COG3038	cytochrome b561
CH60_RS03045	COG3381	protein complex oligomerization
CH60_RS03050	COG3302	dmso reductase anchor subunit
CH60_RS03055	COG0437	4 iron, 4 sulfur cluster binding
CH60_RS03060	COG0243	molybdopterin cofactor binding
CH60_RS03065	COG0235	Class ii aldolase
CH60_RS03070	COG1349	DNA-binding transcription factor activity
CH60_RS03080	COG1129	ABC transporter
CH60_RS03085	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS03095	COG3623	hexulose-6-phosphate isomerase
CH60_RS03100	COG1070	Carbohydrate kinase
CH60_RS03105	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH60_RS03105	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH60_RS03115	COG0024	Methionine aminopeptidase
CH60_RS03130	COG4771	TonB-dependent receptor
CH60_RS03145	COG1858	cytochrome C peroxidase
CH60_RS03150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH60_RS03170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH60_RS03185	COG2376	Dihydroxyacetone kinase
CH60_RS03190	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS03195	COG1063	alcohol dehydrogenase
CH60_RS03200	COG0698	ribose 5-phosphate isomerase
CH60_RS03215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH60_RS03220	COG4942	peptidase
CH60_RS03220	COG1388	LysM domain
CH60_RS03260	COG0529	Catalyzes the synthesis of activated sulfate
CH60_RS03310	COG0720	synthase
CH60_RS03315	COG0602	queuosine metabolic process
CH60_RS03335	COG3956	TIGRFAM MazG family protein
CH60_RS03345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH60_RS03350	COG4999	Histidine kinase
CH60_RS03350	COG3850	Histidine kinase
CH60_RS03350	COG3437	response regulator, receiver
CH60_RS03350	COG2205	protein histidine kinase activity
CH60_RS03355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH60_RS03375	COG2860	membrane
CH60_RS03395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH60_RS03400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH60_RS03410	COG1120	ATPase activity
CH60_RS03415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH60_RS03420	COG1643	Atp-dependent helicase
CH60_RS03425	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH60_RS03440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH60_RS03445	COG0617	tRNA 3'-terminal CCA addition
CH60_RS03450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH60_RS03475	COG0842	Transport permease protein
CH60_RS03480	COG1131	(ABC) transporter
CH60_RS03485	COG0288	reversible hydration of carbon dioxide
CH60_RS03490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH60_RS03495	COG2132	Multicopper oxidase
CH60_RS03515	COG0697	spore germination
CH60_RS03525	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH60_RS03540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH60_RS03545	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH60_RS03550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH60_RS03555	COG2186	Transcriptional regulator
CH60_RS03560	COG1113	amino acid transport
CH60_RS03565	COG3725	Membrane protein required for beta-lactamase induction
CH60_RS03570	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH60_RS03580	COG4969	Belongs to the N-Me-Phe pilin family
CH60_RS03585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH60_RS03590	COG1459	type II secretion system
CH60_RS03645	COG3061	Opacity-associated protein A
CH60_RS03650	COG0545	Peptidyl-prolyl cis-trans isomerase
CH60_RS03660	COG0737	Belongs to the 5'-nucleotidase family
CH60_RS03670	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH60_RS03680	COG1253	flavin adenine dinucleotide binding
CH60_RS03690	COG0729	surface antigen
CH60_RS03695	COG2911	Protein conserved in bacteria
CH60_RS03700	COG2105	PFAM AIG2 family protein
CH60_RS03705	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH60_RS03710	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH60_RS03715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH60_RS03740	COG3423	Transcriptional regulator
CH60_RS03750	COG0142	geranyltranstransferase activity
CH60_RS03765	COG0697	spore germination
CH60_RS03775	COG0642	Histidine kinase
CH60_RS03780	COG0745	RESPONSE REGULATOR receiver
CH60_RS03785	COG2027	D-alanyl-D-alanine carboxypeptidase
CH60_RS03795	COG1534	Rna-binding protein
CH60_RS03810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH60_RS03820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH60_RS03840	COG0195	Participates in both transcription termination and antitermination
CH60_RS03870	COG2801	Transposase and inactivated derivatives
CH60_RS03885	COG0513	Belongs to the DEAD box helicase family
CH60_RS03905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH60_RS03915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH60_RS03925	COG0826	peptidase U32
CH60_RS03930	COG0826	peptidase U32
CH60_RS03940	COG3154	lipid carrier protein
CH60_RS03945	COG3153	acetyltransferase
CH60_RS03965	COG1653	transport
CH60_RS03970	COG1175	transmembrane transport
CH60_RS03975	COG0395	ABC-type sugar transport system, permease component
CH60_RS03995	COG0702	epimerase
CH60_RS04000	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH60_RS04005	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH60_RS04010	COG3454	Phosphonate metabolism
CH60_RS04015	COG4778	phosphonate C-P lyase system protein PhnL
CH60_RS04020	COG4107	phosphonate C-P lyase system protein PhnK
CH60_RS04025	COG3627	carbon phosphorus lyase activity
CH60_RS04030	COG3626	phosphonate metabolism
CH60_RS04035	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH60_RS04040	COG3624	Phosphonate C-P lyase system protein PhnG
CH60_RS04045	COG2188	Transcriptional regulator
CH60_RS04060	COG4608	Belongs to the ABC transporter superfamily
CH60_RS04065	COG0444	Belongs to the ABC transporter superfamily
CH60_RS04070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH60_RS04075	COG0601	transmembrane transport
CH60_RS04085	COG2731	YhcH YjgK YiaL family protein
CH60_RS04095	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH60_RS04105	COG0525	valine-tRNA ligase activity
CH60_RS04110	COG2927	DNA polymerase III (CHI subunit)
CH60_RS04120	COG0795	lipopolysaccharide-transporting ATPase activity
CH60_RS04125	COG0795	lipopolysaccharide-transporting ATPase activity
CH60_RS04135	COG0582	viral genome integration into host DNA
CH60_RS04165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH60_RS04170	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH60_RS04175	COG0564	pseudouridine synthase activity
CH60_RS04185	COG0542	response to heat
CH60_RS04225	COG5544	Lipoprotein
CH60_RS04230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH60_RS04235	COG1042	CoA-binding domain protein
CH60_RS04235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH60_RS04235	COG0045	succinate-CoA ligase (ADP-forming) activity
CH60_RS04240	COG3148	PFAM DTW domain containing protein
CH60_RS04245	COG3118	belongs to the thioredoxin family
CH60_RS04250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH60_RS04255	COG2814	Major facilitator Superfamily
CH60_RS04260	COG1566	PFAM secretion protein HlyD family protein
CH60_RS04265	COG1846	Transcriptional regulator
CH60_RS04275	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH60_RS04280	COG2814	Major facilitator Superfamily
CH60_RS04320	COG0765	amino acid transport
CH60_RS04330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH60_RS04380	COG3842	ATPase activity
CH60_RS04385	COG0395	ABC-type sugar transport system, permease component
CH60_RS04390	COG1175	transmembrane transport
CH60_RS04400	COG0673	inositol 2-dehydrogenase activity
CH60_RS04410	COG2188	Transcriptional regulator
CH60_RS04550	COG2197	response regulator
CH60_RS04560	COG3136	membrane protein required for alginate biosynthesis
CH60_RS04580	COG1113	amino acid transport
CH60_RS04600	COG2822	iron ion transport
CH60_RS04605	COG0672	)-iron permease
CH60_RS04620	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH60_RS04620	COG0506	proline dehydrogenase activity
CH60_RS04620	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH60_RS04635	COG1126	abc transporter atp-binding protein
CH60_RS04640	COG0765	amino acid transport
CH60_RS04645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH60_RS04660	COG1191	sigma factor activity
CH60_RS04695	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH60_RS04700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH60_RS04705	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH60_RS04720	COG1677	Flagellar hook-basal body complex protein FliE
CH60_RS04740	COG1157	protein secretion by the type III secretion system
CH60_RS04755	COG1580	Controls the rotational direction of flagella during chemotaxis
CH60_RS04780	COG1987	bacterial-type flagellum assembly
CH60_RS04800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH60_RS04805	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS04810	COG1129	ABC transporter
CH60_RS04820	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS04825	COG3347	Dehydrogenase
CH60_RS04830	COG2390	Transcriptional regulator
CH60_RS04840	COG1256	bacterial-type flagellum assembly
CH60_RS04880	COG1558	bacterial-type flagellum-dependent cell motility
CH60_RS04885	COG1815	bacterial-type flagellum-dependent cell motility
CH60_RS04895	COG2747	anti-sigma28 factor FlgM
CH60_RS04900	COG3418	PFAM FlgN family protein
CH60_RS04925	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH60_RS04930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH60_RS04960	COG2372	response to copper ion
CH60_RS04965	COG1528	Iron-storage protein
CH60_RS04980	COG1770	oligopeptidase
CH60_RS04995	COG3141	response to X-ray
CH60_RS05000	COG0513	Belongs to the DEAD box helicase family
CH60_RS05025	COG1760	l-serine dehydratase
CH60_RS05030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH60_RS05035	COG2368	4-hydroxyphenylacetate
CH60_RS05050	COG3971	2-oxopent-4-enoate hydratase activity
CH60_RS05060	COG3384	dioxygenase
CH60_RS05065	COG1012	belongs to the aldehyde dehydrogenase family
CH60_RS05080	COG1846	Transcriptional regulator
CH60_RS05085	COG1253	flavin adenine dinucleotide binding
CH60_RS05090	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH60_RS05090	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH60_RS05095	COG3715	PTS system
CH60_RS05100	COG3716	PTS system mannose fructose sorbose family IID component
CH60_RS05140	COG0671	phosphoesterase, PA-phosphatase related
CH60_RS05140	COG2453	phosphatase
CH60_RS05145	COG2267	carboxylic ester hydrolase activity
CH60_RS05155	COG4589	Belongs to the CDS family
CH60_RS05160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH60_RS05205	COG2501	S4 domain
CH60_RS05225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH60_RS05235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH60_RS05240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH60_RS05245	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH60_RS05250	COG4181	ATPase activity
CH60_RS05255	COG2755	lipolytic protein G-D-S-L family
CH60_RS05260	COG0300	oxidoreductase activity
CH60_RS05265	COG3118	belongs to the thioredoxin family
CH60_RS05270	COG0330	HflC and HflK could
CH60_RS05275	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH60_RS05280	COG0789	Transcriptional regulator
CH60_RS05285	COG2217	Heavy metal translocating P-type atpase
CH60_RS05290	COG3735	TraB family
CH60_RS05295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH60_RS05310	COG0737	Belongs to the 5'-nucleotidase family
CH60_RS05315	COG0737	Belongs to the 5'-nucleotidase family
CH60_RS05320	COG0737	Belongs to the 5'-nucleotidase family
CH60_RS05325	COG2223	nitrite transmembrane transporter activity
CH60_RS05330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH60_RS05330	COG4651	solute:proton antiporter activity
CH60_RS05335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH60_RS05340	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH60_RS05360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH60_RS05400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH60_RS05420	COG0543	2 iron, 2 sulfur cluster binding
CH60_RS05420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH60_RS05450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH60_RS05475	COG3264	Mechanosensitive ion channel
CH60_RS05475	COG1196	nuclear chromosome segregation
CH60_RS05480	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH60_RS05485	COG1309	transcriptional regulator
CH60_RS05490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH60_RS05495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH60_RS05505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH60_RS05525	COG3695	enzyme binding
CH60_RS05530	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH60_RS05535	COG1946	Acyl-CoA thioesterase
CH60_RS05540	COG0004	ammonium transporteR
CH60_RS05545	COG0347	Belongs to the P(II) protein family
CH60_RS05550	COG1132	(ABC) transporter
CH60_RS05555	COG1132	(ABC) transporter
CH60_RS05560	COG1522	sequence-specific DNA binding
CH60_RS05575	COG4533	DNA binding
CH60_RS05585	COG0824	Thioesterase
CH60_RS05590	COG1555	photosystem II stabilization
CH60_RS05595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH60_RS05600	COG0776	regulation of translation
CH60_RS05605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH60_RS05630	COG0271	Belongs to the BolA IbaG family
CH60_RS05635	COG3056	Lipoprotein
CH60_RS05640	COG2223	nitrite transmembrane transporter activity
CH60_RS05650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH60_RS05655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH60_RS05660	COG1845	cytochrome c oxidase, subunit III
CH60_RS05665	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH60_RS05675	COG2814	Major facilitator Superfamily
CH60_RS05685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH60_RS05690	COG0693	protein deglycase activity
CH60_RS05710	COG0142	geranyltranstransferase activity
CH60_RS05730	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH60_RS05735	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH60_RS05750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH60_RS05750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH60_RS05775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH60_RS05780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH60_RS05785	COG1862	Preprotein translocase
CH60_RS05805	COG0450	alkyl hydroperoxide reductase
CH60_RS05830	COG0366	Alpha amylase catalytic
CH60_RS05850	COG5002	protein histidine kinase activity
CH60_RS05855	COG0745	RESPONSE REGULATOR receiver
CH60_RS05865	COG0420	3'-5' exonuclease activity
CH60_RS05870	COG0419	ATPase involved in DNA repair
CH60_RS05875	COG1940	carbohydrate kinase activity
CH60_RS05910	COG2226	methyltransferase
CH60_RS05970	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH60_RS05990	COG1477	protein flavinylation
CH60_RS06010	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH60_RS06015	COG1805	sodium ion transport
CH60_RS06025	COG3034	peptidoglycan biosynthetic process
CH60_RS06030	COG0121	glutamine amidotransferase
CH60_RS06040	COG1960	acyl-CoA dehydrogenase activity
CH60_RS06050	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH60_RS06070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH60_RS06085	COG0582	viral genome integration into host DNA
CH60_RS06090	COG2963	transposase activity
CH60_RS06095	COG0582	viral genome integration into host DNA
CH60_RS06105	COG0596	Alpha beta hydrolase
CH60_RS06125	COG0735	belongs to the Fur family
CH60_RS06145	COG1263	PTS System
CH60_RS06145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH60_RS06145	COG2190	(PTS) system
CH60_RS06155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH60_RS06160	COG1940	carbohydrate kinase activity
CH60_RS06160	COG1846	Transcriptional regulator
CH60_RS06165	COG0647	UMP catabolic process
CH60_RS06170	COG0367	asparagine synthase
CH60_RS06210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH60_RS06220	COG1702	phosphate starvation-inducible protein PhoH
CH60_RS06230	COG4535	Mg2 and Co2 transporter CorC
CH60_RS06235	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH60_RS06245	COG0765	amino acid transport
CH60_RS06250	COG0765	amino acid transport
CH60_RS06255	COG1126	abc transporter atp-binding protein
CH60_RS06260	COG2888	peptidyl-tyrosine sulfation
CH60_RS06275	COG1466	dna polymerase III delta subunit
CH60_RS06285	COG0799	negative regulation of ribosome biogenesis
CH60_RS06295	COG0768	penicillin binding
CH60_RS06300	COG0772	Belongs to the SEDS family
CH60_RS06305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH60_RS06310	COG1686	Belongs to the peptidase S11 family
CH60_RS06330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH60_RS06340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH60_RS06350	COG1278	Cold shock
CH60_RS06355	COG2197	response regulator
CH60_RS06380	COG5265	(ABC) transporter
CH60_RS06390	COG3718	enzyme involved in inositol metabolism
CH60_RS06400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH60_RS06405	COG0673	inositol 2-dehydrogenase activity
CH60_RS06410	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS06415	COG1129	ABC transporter
CH60_RS06430	COG3962	Belongs to the TPP enzyme family
CH60_RS06450	COG2373	Large extracellular alpha-helical protein
CH60_RS06455	COG4953	penicillin-binding protein 1C
CH60_RS06460	COG3423	Transcriptional regulator
CH60_RS06510	COG2850	peptidyl-arginine hydroxylation
CH60_RS06530	COG1472	Belongs to the glycosyl hydrolase 3 family
CH60_RS06550	COG0656	L-ascorbic acid biosynthetic process
CH60_RS06555	COG0667	Aldo Keto reductase
CH60_RS06575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH60_RS06590	COG3130	regulation of translation
CH60_RS06600	COG3009	Protein conserved in bacteria
CH60_RS06605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH60_RS06605	COG3008	intermembrane lipid transfer
CH60_RS06610	COG2995	paraquat-inducible protein a
CH60_RS06615	COG0488	(ABC) transporter
CH60_RS06625	COG0633	Ferredoxin
CH60_RS06625	COG3217	Mosc domain protein beta barrel domain protein
CH60_RS06640	COG0308	aminopeptidase N
CH60_RS06660	COG1448	Aminotransferase
CH60_RS06665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH60_RS06670	COG3108	Peptidase M15
CH60_RS06675	COG2989	Protein conserved in bacteria
CH60_RS06705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH60_RS06715	COG3173	Aminoglycoside phosphotransferase
CH60_RS06730	COG1278	Cold shock
CH60_RS06740	COG5383	Protein conserved in bacteria
CH60_RS06755	COG0658	competence protein
CH60_RS06755	COG2333	competence protein COMEC
CH60_RS06765	COG0539	negative regulation of cytoplasmic translation
CH60_RS06790	COG5295	Hep Hag repeat protein
CH60_RS06790	COG5295	Hep Hag repeat protein
CH60_RS06795	COG0252	asparaginase activity
CH60_RS06800	COG1944	ATP diphosphatase activity
CH60_RS06805	COG2116	formate transmembrane transporter activity
CH60_RS06810	COG1882	Formate acetyltransferase
CH60_RS06820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH60_RS06835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH60_RS06845	COG3107	peptidoglycan biosynthetic process
CH60_RS06845	COG1674	ftsk spoiiie
CH60_RS06855	COG0492	ferredoxin-NADP+ reductase activity
CH60_RS06870	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH60_RS06880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH60_RS06890	COG0542	response to heat
CH60_RS06900	COG1278	Cold shock
CH60_RS06910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH60_RS06915	COG2990	Protein conserved in bacteria
CH60_RS06920	COG3593	DNA synthesis involved in DNA repair
CH60_RS06925	COG2431	L-lysine efflux transmembrane transporter activity
CH60_RS06935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH60_RS06940	COG0028	Belongs to the TPP enzyme family
CH60_RS06945	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH60_RS06950	COG0702	epimerase
CH60_RS06955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH60_RS06965	COG1605	Chorismate mutase
CH60_RS06970	COG1126	abc transporter atp-binding protein
CH60_RS06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH60_RS06980	COG4215	(ABC) transporter
CH60_RS06985	COG4160	amino acid transport
CH60_RS07010	COG1120	ATPase activity
CH60_RS07040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH60_RS07055	COG1177	transmembrane transport
CH60_RS07060	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH60_RS07065	COG3842	ATPase activity
CH60_RS07070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH60_RS07105	COG0671	phosphoesterase, PA-phosphatase related
CH60_RS07115	COG1349	DNA-binding transcription factor activity
CH60_RS07120	COG0814	amino acid
CH60_RS07130	COG1686	Belongs to the peptidase S11 family
CH60_RS07135	COG2011	ABC-type metal ion transport system permease component
CH60_RS07160	COG0625	glutathione transferase activity
CH60_RS07165	COG4771	TonB-dependent receptor
CH60_RS07175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH60_RS07185	COG0833	amino acid
CH60_RS07190	COG0583	DNA-binding transcription factor activity
CH60_RS07195	COG2855	membrane
CH60_RS07240	COG0288	reversible hydration of carbon dioxide
CH60_RS07260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH60_RS07325	COG0840	transmembrane signaling receptor activity
CH60_RS07340	COG0583	DNA-binding transcription factor activity
CH60_RS07345	COG2814	Major facilitator Superfamily
CH60_RS07350	COG0583	DNA-binding transcription factor activity
CH60_RS07360	COG1609	Transcriptional regulator
CH60_RS07390	COG0667	Aldo Keto reductase
CH60_RS07455	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH60_RS07465	COG1074	ATP-dependent DNA helicase activity
CH60_RS07470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH60_RS07480	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH60_RS07495	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH60_RS07500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH60_RS07505	COG2166	iron-sulfur cluster assembly
CH60_RS07510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH60_RS07515	COG0583	DNA-binding transcription factor activity
CH60_RS07520	COG2363	Small membrane protein
CH60_RS07535	COG1611	Belongs to the LOG family
CH60_RS07555	COG3098	single-species biofilm formation
CH60_RS07560	COG0564	pseudouridine synthase activity
CH60_RS07620	COG0575	Belongs to the CDS family
CH60_RS07625	COG0750	zinc metalloprotease
CH60_RS07640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH60_RS07665	COG0587	DNA-directed DNA polymerase activity
CH60_RS07675	COG0346	lactoylglutathione lyase activity
CH60_RS07680	COG0037	tRNA processing
CH60_RS07690	COG4568	rho-dependent transcription termination
CH60_RS07700	COG4681	YaeQ
CH60_RS07710	COG3015	lipoprotein NlpE involved in copper resistance
CH60_RS07720	COG1720	tRNA m6t6A37 methyltransferase activity
CH60_RS07730	COG1464	Belongs to the NlpA lipoprotein family
CH60_RS07735	COG2011	ABC-type metal ion transport system permease component
CH60_RS07745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH60_RS07785	COG0656	L-ascorbic acid biosynthetic process
CH60_RS07800	COG1388	LysM domain
CH60_RS07800	COG0741	lytic transglycosylase activity
CH60_RS07805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH60_RS07810	COG2226	methyltransferase
CH60_RS07830	COG1953	Uracil, thiamine, allantoin
CH60_RS07870	COG2113	Glycine betaine
CH60_RS07875	COG4176	ABC-type proline glycine betaine transport system permease component
CH60_RS07880	COG4175	Glycine betaine
CH60_RS07885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH60_RS07915	COG3328	transposase activity
CH60_RS07920	COG3188	usher protein
CH60_RS08020	COG0351	phosphomethylpyrimidine kinase
CH60_RS08040	COG0826	peptidase U32
CH60_RS08045	COG3422	double-strand break repair
CH60_RS08050	COG0745	RESPONSE REGULATOR receiver
CH60_RS08055	COG2205	protein histidine kinase activity
CH60_RS08080	COG3842	ATPase activity
CH60_RS08090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH60_RS08100	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH60_RS08105	COG1177	transmembrane transport
CH60_RS08110	COG0443	Heat shock 70 kDa protein
CH60_RS08115	COG2239	Acts as a magnesium transporter
CH60_RS08130	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH60_RS08140	COG0581	inorganic phosphate transmembrane transporter activity
CH60_RS08160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH60_RS08165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH60_RS08190	COG1393	Belongs to the ArsC family
CH60_RS08195	COG4783	chaperone-mediated protein folding
CH60_RS08200	COG0628	permease
CH60_RS08220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH60_RS08225	COG2716	regulation of RNA biosynthetic process
CH60_RS08235	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH60_RS08255	COG2321	neutral zinc metallopeptidase
CH60_RS08275	COG1876	peptidase activity
CH60_RS08285	COG1393	Belongs to the ArsC family
CH60_RS08300	COG1175	transmembrane transport
CH60_RS08305	COG3842	ATPase activity
CH60_RS08310	COG3119	arylsulfatase activity
CH60_RS08315	COG0641	radical SAM
CH60_RS08320	COG1988	membrane-bound metal-dependent
CH60_RS08330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH60_RS08340	COG2197	response regulator
CH60_RS08345	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH60_RS08345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH60_RS08350	COG3062	negative regulation of establishment of protein localization
CH60_RS08360	COG3043	anaerobic respiration
CH60_RS08365	COG3005	denitrification pathway
CH60_RS08410	COG3111	PFAM Bacterial OB fold (BOF) protein
CH60_RS08420	COG2837	iron assimilation
CH60_RS08425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH60_RS08435	COG4886	Leucine-rich repeat (LRR) protein
CH60_RS08445	COG2731	YhcH YjgK YiaL family protein
CH60_RS08455	COG1737	Transcriptional regulator
CH60_RS08465	COG4150	thiosulfate binding
CH60_RS08470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH60_RS08475	COG4208	sulfate ABC transporter
CH60_RS08480	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH60_RS08495	COG0745	RESPONSE REGULATOR receiver
CH60_RS08500	COG3850	Histidine kinase
CH60_RS08500	COG5002	protein histidine kinase activity
CH60_RS08510	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH60_RS08530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH60_RS08545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH60_RS08550	COG0745	RESPONSE REGULATOR receiver
CH60_RS08555	COG2205	protein histidine kinase activity
CH60_RS08580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH60_RS08590	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH60_RS08605	COG3530	Putative quorum-sensing-regulated virulence factor
CH60_RS08650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH60_RS08665	COG0667	Aldo Keto reductase
CH60_RS08690	COG0436	Aminotransferase
CH60_RS08695	COG3038	cytochrome b561
CH60_RS08725	COG3381	protein complex oligomerization
CH60_RS08730	COG3302	dmso reductase anchor subunit
CH60_RS08735	COG0437	4 iron, 4 sulfur cluster binding
CH60_RS08740	COG0243	molybdopterin cofactor binding
CH60_RS08775	COG2951	lytic endotransglycosylase activity
CH60_RS08835	COG3121	Chaperone
CH60_RS08840	COG3188	usher protein
CH60_RS08845	COG3328	transposase activity
CH60_RS08860	COG1278	Cold shock
CH60_RS08865	COG0747	negative chemotaxis
CH60_RS08875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH60_RS08880	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH60_RS08885	COG1124	(ABC) transporter
CH60_RS08890	COG0831	urea catabolic process
CH60_RS08915	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH60_RS08925	COG4413	Urea transporter
CH60_RS08930	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH60_RS08945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH60_RS08955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH60_RS08965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH60_RS08970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH60_RS08975	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH60_RS08980	COG1917	Cupin 2, conserved barrel domain protein
CH60_RS08980	COG2169	Transcriptional regulator
CH60_RS09000	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH60_RS09005	COG0033	Phosphoglucomutase
CH60_RS09025	COG0745	RESPONSE REGULATOR receiver
CH60_RS09030	COG2205	protein histidine kinase activity
CH60_RS09065	COG3272	Protein of unknown function (DUF1722)
CH60_RS09075	COG5212	phosphodiesterase
CH60_RS09080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH60_RS09090	COG1984	allophanate hydrolase subunit 2
CH60_RS09150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH60_RS09165	COG3026	antisigma factor binding
CH60_RS09170	COG3086	response to oxidative stress
CH60_RS09205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH60_RS09225	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH60_RS09230	COG1737	Transcriptional regulator
CH60_RS09255	COG1737	Transcriptional regulator
CH60_RS09265	COG0560	Phosphoserine phosphatase
CH60_RS09305	COG2205	protein histidine kinase activity
CH60_RS09310	COG3170	Tfp pilus assembly protein FimV
CH60_RS09315	COG2204	response regulator
CH60_RS09320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH60_RS09320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH60_RS09325	COG0347	Belongs to the P(II) protein family
CH60_RS09330	COG2188	Transcriptional regulator
CH60_RS09335	COG2188	Transcriptional regulator
CH60_RS09340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH60_RS09340	COG1017	nitric oxide dioxygenase activity
CH60_RS09360	COG2814	Major facilitator Superfamily
CH60_RS09365	COG3711	transcriptional antiterminator
CH60_RS09370	COG3683	transport system, periplasmic component
CH60_RS09375	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH60_RS09395	COG1104	cysteine desulfurase activity
CH60_RS09400	COG0822	iron-sulfur transferase activity
CH60_RS09415	COG0443	Heat shock 70 kDa protein
CH60_RS09420	COG0633	Ferredoxin
CH60_RS09425	COG2975	iron-sulfur cluster assembly
CH60_RS09445	COG3468	outer membrane autotransporter barrel domain protein
CH60_RS09450	COG3468	outer membrane autotransporter barrel domain protein
CH60_RS09495	COG2976	Protein conserved in bacteria
CH60_RS09500	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH60_RS09515	COG1645	bacterial-type flagellum-dependent swarming motility
CH60_RS09525	COG0517	IMP dehydrogenase activity
CH60_RS09525	COG0516	GMP reductase activity
CH60_RS09580	COG3328	transposase activity
CH60_RS09585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH60_RS09595	COG3001	Fructosamine kinase
CH60_RS09605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH60_RS09610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH60_RS09615	COG1121	(ABC) transporter
CH60_RS09620	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH60_RS09645	COG4249	Peptidase C14 caspase catalytic subunit p20
CH60_RS09675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH60_RS09675	COG0072	phenylalanine-tRNA ligase activity
CH60_RS09680	COG0776	regulation of translation
CH60_RS09695	COG0386	Belongs to the glutathione peroxidase family
CH60_RS09740	COG0791	NLP P60 protein
CH60_RS09765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH60_RS09765	COG0574	Belongs to the PEP-utilizing enzyme family
CH60_RS09770	COG0628	permease
CH60_RS09775	COG0247	lactate metabolic process
CH60_RS09775	COG0277	FAD linked oxidase domain protein
CH60_RS09780	COG2050	protein possibly involved in aromatic compounds catabolism
CH60_RS09790	COG0316	Belongs to the HesB IscA family
CH60_RS09795	COG0719	Fe-S assembly protein
CH60_RS09800	COG0396	ATPase activity
CH60_RS09805	COG0719	Fe-S assembly protein
CH60_RS09820	COG1388	LysM domain
CH60_RS09820	COG1376	ErfK ybiS ycfS ynhG family protein
CH60_RS09875	COG0307	riboflavin synthase, alpha
CH60_RS09880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH60_RS09885	COG2814	Major facilitator Superfamily
CH60_RS09890	COG0583	DNA-binding transcription factor activity
CH60_RS09905	COG0791	NLP P60 protein
CH60_RS09915	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH60_RS09920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH60_RS09925	COG0346	lactoylglutathione lyase activity
CH60_RS09935	COG1902	pentaerythritol trinitrate reductase activity
CH60_RS09940	COG1309	transcriptional regulator
CH60_RS09945	COG2194	sulfuric ester hydrolase activity
CH60_RS09950	COG3313	Fe-S protein
CH60_RS09955	COG4989	oxidoreductase activity
CH60_RS09965	COG3133	Outer membrane lipoprotein
CH60_RS09975	COG3895	Periplasmic Protein
CH60_RS09995	COG0625	glutathione transferase activity
CH60_RS10010	COG3104	oligopeptide transport
CH60_RS10015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH60_RS10015	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH60_RS10020	COG4172	Belongs to the ABC transporter superfamily
CH60_RS10030	COG4171	peptide transport system, permease
CH60_RS10035	COG4168	peptide transport system, permease
CH60_RS10040	COG4166	transmembrane transport
CH60_RS10065	COG5642	Protein of unknown function (DUF2384)
CH60_RS10070	COG5654	RES domain protein
CH60_RS10080	COG3106	COG3106 Predicted ATPase
CH60_RS10090	COG1983	PspC domain protein
CH60_RS10100	COG1842	Phage shock protein A
CH60_RS10105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH60_RS10115	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH60_RS10120	COG4948	Mandelate Racemase Muconate Lactonizing
CH60_RS10125	COG2866	Carboxypeptidase
CH60_RS10130	COG4166	transmembrane transport
CH60_RS10150	COG0657	acetylesterase activity
CH60_RS10160	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH60_RS10160	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH60_RS10160	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH60_RS10160	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH60_RS10170	COG1285	pathogenesis
CH60_RS10175	COG3042	response to heat
CH60_RS10180	COG3187	Heat shock protein
CH60_RS10185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH60_RS10190	COG2911	Protein conserved in bacteria
CH60_RS10200	COG3784	Protein of unknown function (DUF1318)
CH60_RS10205	COG0246	Mannitol dehydrogenase
CH60_RS10210	COG2390	Transcriptional regulator
CH60_RS10220	COG1643	Atp-dependent helicase
CH60_RS10235	COG3591	Belongs to the peptidase S1B family
CH60_RS10250	COG3038	cytochrome b561
CH60_RS10285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH60_RS10290	COG2205	protein histidine kinase activity
CH60_RS10295	COG0745	RESPONSE REGULATOR receiver
CH60_RS10305	COG0531	amino acid
CH60_RS10320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH60_RS10325	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH60_RS10330	COG0589	response to stress
CH60_RS10335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH60_RS10340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH60_RS10360	COG1011	Hydrolase
CH60_RS10365	COG0440	acetolactate synthase activity
CH60_RS10370	COG0028	Belongs to the TPP enzyme family
CH60_RS10395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH60_RS10405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH60_RS10425	COG1609	Transcriptional regulator
CH60_RS10435	COG0038	chloride channel
CH60_RS10440	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH60_RS10445	COG1940	carbohydrate kinase activity
CH60_RS10450	COG0583	DNA-binding transcription factor activity
CH60_RS10465	COG0114	fumarate hydratase activity
CH60_RS10475	COG5339	Protein conserved in bacteria
CH60_RS10485	COG0385	Bile acid
CH60_RS10490	COG0673	inositol 2-dehydrogenase activity
CH60_RS10500	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS10505	COG1129	ABC transporter
CH60_RS10510	COG1879	ABC-type sugar transport system periplasmic component
CH60_RS10525	COG2274	protein secretion by the type I secretion system
CH60_RS10530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH60_RS10540	COG1132	(ABC) transporter
CH60_RS10570	COG2207	Transcriptional regulator
CH60_RS10570	COG3708	Transcriptional regulator
CH60_RS10575	COG4658	electron transport chain
CH60_RS10580	COG4659	FMN binding
CH60_RS10590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH60_RS10595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH60_RS10600	COG2271	Major facilitator Superfamily
CH60_RS10610	COG1966	Carbon starvation protein
CH60_RS10615	COG2879	small protein
CH60_RS10620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH60_RS10640	COG0023	Translation Initiation Factor
CH60_RS10655	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH60_RS10660	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH60_RS10665	COG0671	phosphoesterase, PA-phosphatase related
CH60_RS10675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH60_RS10685	COG0583	DNA-binding transcription factor activity
CH60_RS10705	COG0616	signal peptide processing
CH60_RS10710	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS10720	COG1187	pseudouridine synthase activity
CH60_RS10725	COG0009	L-threonylcarbamoyladenylate synthase
CH60_RS10750	COG0512	Glutamine amidotransferase of anthranilate synthase
CH60_RS10760	COG0135	phosphoribosylanthranilate isomerase activity
CH60_RS10760	COG0134	indole-3-glycerol-phosphate synthase activity
CH60_RS10780	COG3047	cAMP biosynthetic process
CH60_RS10820	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH60_RS10825	COG2350	Protein conserved in bacteria
CH60_RS10865	COG4608	Belongs to the ABC transporter superfamily
CH60_RS10870	COG0444	Belongs to the ABC transporter superfamily
CH60_RS10875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH60_RS10880	COG0601	transmembrane transport
CH60_RS10890	COG2095	MarC family integral membrane protein
CH60_RS10895	COG1012	belongs to the aldehyde dehydrogenase family
CH60_RS10895	COG1454	alcohol dehydrogenase
CH60_RS10915	COG0745	RESPONSE REGULATOR receiver
CH60_RS10925	COG0788	formyltetrahydrofolate deformylase activity
CH60_RS10935	COG0583	DNA-binding transcription factor activity
CH60_RS10940	COG0708	Exodeoxyribonuclease III
CH60_RS10945	COG0494	nUDIX hydrolase
CH60_RS10955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH60_RS10960	COG0709	Synthesizes selenophosphate from selenide and ATP
CH60_RS10965	COG0778	Nitroreductase
CH60_RS10970	COG0616	signal peptide processing
CH60_RS10975	COG0252	asparaginase activity
CH60_RS10980	COG1335	isochorismatase
CH60_RS10985	COG3139	Protein of unknown function (DUF1315)
CH60_RS11005	COG3713	MltA-interacting MipA family protein
CH60_RS11010	COG2766	serine protein kinase
CH60_RS11025	COG0583	DNA-binding transcription factor activity
CH60_RS11035	COG2814	Major facilitator Superfamily
CH60_RS11045	COG2719	SpoVR family
CH60_RS11075	COG1104	cysteine desulfurase activity
CH60_RS11145	COG0582	viral genome integration into host DNA
CH60_RS11155	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH60_RS11160	COG2951	lytic endotransglycosylase activity
CH60_RS11175	COG2894	cell division
CH60_RS11180	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH60_RS11185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH60_RS11190	COG0318	PFAM AMP-dependent synthetase and ligase
CH60_RS11195	COG3065	identical protein binding
CH60_RS11205	COG1199	ATP-dependent helicase activity
CH60_RS11210	COG0251	oxidation-reduction process
CH60_RS11225	COG0800	Aldolase
CH60_RS11235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH60_RS11240	COG1737	Transcriptional regulator
CH60_RS11245	COG0469	pyruvate kinase activity
CH60_RS11250	COG1560	Kdo2-lipid A biosynthetic process
CH60_RS11255	COG0739	heme binding
CH60_RS11260	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH60_RS11270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH60_RS11295	COG0494	nUDIX hydrolase
CH60_RS11310	COG1801	Protein of unknown function DUF72
CH60_RS11315	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH60_RS11335	COG3102	Protein conserved in bacteria
CH60_RS11355	COG0728	peptidoglycan biosynthetic process
CH60_RS11360	COG0673	inositol 2-dehydrogenase activity
CH60_RS11365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH60_RS11380	COG3381	protein complex oligomerization
CH60_RS11395	COG1940	carbohydrate kinase activity
CH60_RS11400	COG0584	glycerophosphoryl diester phosphodiesterase
CH60_RS11405	COG3842	ATPase activity
CH60_RS11420	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH60_RS11425	COG3833	ABC-type maltose transport systems, permease component
CH60_RS11450	COG0659	secondary active sulfate transmembrane transporter activity
CH60_RS11470	COG2890	protein-(glutamine-N5) methyltransferase activity
CH60_RS11500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH60_RS11520	COG0012	GTP binding
CH60_RS11575	COG5002	protein histidine kinase activity
CH60_RS11615	COG0500	methyltransferase
CH60_RS11640	COG3328	transposase activity
CH60_RS11680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH60_RS11685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH60_RS11690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH60_RS11705	COG0402	S-adenosylhomocysteine deaminase activity
CH60_RS11745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH60_RS11750	COG3328	transposase activity
CH60_RS11760	COG5295	Hep Hag repeat protein
CH60_RS11770	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH60_RS11780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH60_RS11785	COG0745	RESPONSE REGULATOR receiver
CH60_RS11795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH60_RS11800	COG0840	transmembrane signaling receptor activity
CH60_RS11805	COG0840	transmembrane signaling receptor activity
CH60_RS11825	COG2964	Protein conserved in bacteria
CH60_RS11835	COG0251	oxidation-reduction process
CH60_RS11840	COG2271	Major facilitator Superfamily
CH60_RS11845	COG0835	chemotaxis
CH60_RS11850	COG0643	Histidine kinase
CH60_RS11850	COG2198	Histidine kinase
CH60_RS11855	COG1360	Flagellar Motor Protein
CH60_RS11880	COG1285	pathogenesis
CH60_RS11910	COG0604	alcohol dehydrogenase
CH60_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS11910	COG3321	synthase
CH60_RS11920	COG1522	sequence-specific DNA binding
CH60_RS11945	COG1733	regulation of RNA biosynthetic process
CH60_RS11950	COG0702	epimerase
CH60_RS11955	COG0840	transmembrane signaling receptor activity
CH60_RS11970	COG0538	isocitrate dehydrogenase activity
CH60_RS11975	COG1187	pseudouridine synthase activity
CH60_RS11995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH60_RS12005	COG0745	RESPONSE REGULATOR receiver
CH60_RS12015	COG2850	peptidyl-arginine hydroxylation
CH60_RS12030	COG1940	carbohydrate kinase activity
CH60_RS12035	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH60_RS12045	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH60_RS12050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH60_RS12055	COG3134	Outer membrane lipoprotein
CH60_RS12075	COG1252	NADH dehydrogenase
CH60_RS12085	COG1472	Belongs to the glycosyl hydrolase 3 family
CH60_RS12100	COG5633	Lipoprotein
CH60_RS12105	COG0537	adenosine 5'-monophosphoramidase activity
CH60_RS12110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH60_RS12120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH60_RS12120	COG1263	PTS System
CH60_RS12125	COG0084	hydrolase, TatD family'
CH60_RS12130	COG0470	DNA polymerase III
CH60_RS12140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH60_RS12145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH60_RS12155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH60_RS12185	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH60_RS12190	COG1399	metal-binding, possibly nucleic acid-binding protein
CH60_RS12195	COG0424	maF-like protein
CH60_RS12200	COG0564	pseudouridine synthase activity
CH60_RS12205	COG1530	ribonuclease E activity
CH60_RS12210	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH60_RS12235	COG3328	transposase activity
CH60_RS12250	COG0628	permease
CH60_RS12280	COG3916	Acyl-homoserine-lactone synthase
CH60_RS12285	COG2771	luxR family
CH60_RS12290	COG0583	DNA-binding transcription factor activity
CH60_RS12300	COG0477	Major facilitator Superfamily
CH60_RS12310	COG0667	Aldo Keto reductase
CH60_RS12335	COG1203	CRISPR-associated helicase, Cas3
CH60_RS12340	COG1518	maintenance of DNA repeat elements
CH60_RS12350	COG0668	transmembrane transport
CH60_RS12370	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH60_RS12375	COG0395	ABC-type sugar transport system, permease component
CH60_RS12390	COG1609	Transcriptional regulator
CH60_RS12405	COG3842	ATPase activity
CH60_RS12415	COG3210	domain, Protein
CH60_RS12435	COG3210	domain, Protein
CH60_RS12440	COG2831	hemolysin activation secretion protein
CH60_RS12445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH60_RS12450	COG4638	Rieske (2fe-2S)
CH60_RS12455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH60_RS12465	COG0473	3-isopropylmalate dehydrogenase activity
CH60_RS12470	COG0583	DNA-binding transcription factor activity
CH60_RS12475	COG1609	Transcriptional regulator
CH60_RS12480	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS12485	COG1129	ABC transporter
CH60_RS12490	COG1879	ABC-type sugar transport system periplasmic component
CH60_RS12495	COG1063	alcohol dehydrogenase
CH60_RS12515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH60_RS12545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH60_RS12550	COG0765	amino acid transport
CH60_RS12555	COG1126	abc transporter atp-binding protein
CH60_RS12575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH60_RS12590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH60_RS12605	COG1169	isochorismate synthase
CH60_RS12615	COG4575	ribosome binding
CH60_RS12630	COG0129	dihydroxy-acid dehydratase activity
CH60_RS12645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH60_RS12655	COG1609	Transcriptional regulator
CH60_RS12660	COG1649	PFAM Uncharacterised BCR, COG1649
CH60_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS12670	COG3265	gluconokinase activity
CH60_RS12675	COG2731	YhcH YjgK YiaL family protein
CH60_RS12690	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH60_RS12695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH60_RS12705	COG0839	Belongs to the complex I subunit 6 family
CH60_RS12720	COG1034	ATP synthesis coupled electron transport
CH60_RS12740	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH60_RS12750	COG0583	DNA-binding transcription factor activity
CH60_RS12760	COG0436	Aminotransferase
CH60_RS12775	COG0471	metal ion transport
CH60_RS12775	COG0490	domain, Protein
CH60_RS12780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH60_RS12805	COG0857	belongs to the CobB CobQ family
CH60_RS12805	COG0280	phosphate acetyltransferase
CH60_RS12810	COG1609	Transcriptional regulator
CH60_RS12825	COG3328	transposase activity
CH60_RS12845	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH60_RS12850	COG0622	Phosphoesterase
CH60_RS12860	COG1090	epimerase
CH60_RS12865	COG4598	ABC transporter
CH60_RS12870	COG4160	amino acid transport
CH60_RS12875	COG4215	(ABC) transporter
CH60_RS12880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH60_RS12890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH60_RS12895	COG1286	toxin biosynthetic process
CH60_RS12900	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH60_RS12905	COG0285	dihydrofolate synthase activity
CH60_RS12915	COG0586	Pfam SNARE associated Golgi protein
CH60_RS12925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH60_RS12945	COG0697	spore germination
CH60_RS12960	COG1794	racemase activity, acting on amino acids and derivatives
CH60_RS12965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH60_RS12980	COG3101	peptidyl-lysine hydroxylation
CH60_RS12985	COG0730	response to heat
CH60_RS13000	COG2890	protein-(glutamine-N5) methyltransferase activity
CH60_RS13010	COG2062	phosphohistidine phosphatase, SixA
CH60_RS13025	COG3691	Protein conserved in bacteria
CH60_RS13040	COG4235	cytochrome complex assembly
CH60_RS13040	COG3088	subunit of a heme lyase
CH60_RS13045	COG4235	cytochrome complex assembly
CH60_RS13045	COG3088	subunit of a heme lyase
CH60_RS13050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH60_RS13055	COG1138	Cytochrome C-type biogenesis protein
CH60_RS13065	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH60_RS13070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH60_RS13075	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH60_RS13095	COG1704	LemA family
CH60_RS13105	COG2824	Alkylphosphonate utilization operon protein PhnA
CH60_RS13115	COG3328	transposase activity
CH60_RS13120	COG1917	Cupin 2, conserved barrel domain protein
CH60_RS13130	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS13140	COG1175	transmembrane transport
CH60_RS13150	COG3842	ATPase activity
CH60_RS13155	COG1653	transport
CH60_RS13160	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH60_RS13165	COG1988	membrane-bound metal-dependent
CH60_RS13170	COG1823	symporter activity
CH60_RS13175	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH60_RS13185	COG0823	Involved in the tonB-independent uptake of proteins
CH60_RS13190	COG2814	Major facilitator Superfamily
CH60_RS13195	COG3121	Chaperone
CH60_RS13210	COG3121	Chaperone
CH60_RS13215	COG3539	Fimbrial protein
CH60_RS13225	COG0793	Belongs to the peptidase S41A family
CH60_RS13235	COG1956	GAF domain-containing protein
CH60_RS13240	COG2995	paraquat-inducible protein a
CH60_RS13245	COG3008	intermembrane lipid transfer
CH60_RS13265	COG3121	Chaperone
CH60_RS13350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH60_RS13355	COG3850	Histidine kinase
CH60_RS13360	COG0387	Pfam Sodium calcium exchanger
CH60_RS13365	COG1702	phosphate starvation-inducible protein PhoH
CH60_RS13380	COG3658	cytochrome
CH60_RS13385	COG1215	transferase activity, transferring glycosyl groups
CH60_RS13390	COG1649	PFAM Uncharacterised BCR, COG1649
CH60_RS13390	COG0726	polysaccharide deacetylase
CH60_RS13395	COG0457	Tetratricopeptide repeat
CH60_RS13400	COG0006	proline dipeptidase activity
CH60_RS13420	COG1136	(ABC) transporter
CH60_RS13420	COG0577	efflux transmembrane transporter activity
CH60_RS13430	COG0577	efflux transmembrane transporter activity
CH60_RS13430	COG1136	(ABC) transporter
CH60_RS13445	COG0672	)-iron permease
CH60_RS13455	COG2066	Belongs to the glutaminase family
CH60_RS13460	COG1349	DNA-binding transcription factor activity
CH60_RS13470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH60_RS13475	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH60_RS13490	COG2814	Major facilitator Superfamily
CH60_RS13515	COG2030	dehydratase
CH60_RS13520	COG0427	acetyl-CoA hydrolase
CH60_RS13545	COG3188	usher protein
CH60_RS13555	COG3121	Chaperone
CH60_RS13565	COG0582	viral genome integration into host DNA
CH60_RS13570	COG1169	isochorismate synthase
CH60_RS13575	COG2814	Major facilitator Superfamily
CH60_RS13580	COG1132	(ABC) transporter
CH60_RS13595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH60_RS13595	COG3433	isochorismatase activity
CH60_RS13595	COG2226	methyltransferase
CH60_RS13615	COG1021	2,3-dihydroxybenzoate-AMP ligase
CH60_RS13620	COG4771	TonB-dependent receptor
CH60_RS13680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH60_RS13695	COG1067	ATP-dependent peptidase activity
CH60_RS13715	COG3082	Protein of unknown function (DUF1414)
CH60_RS13720	COG3083	sulfuric ester hydrolase activity
CH60_RS13735	COG3157	Type VI secretion system effector, Hcp
CH60_RS13765	COG0513	Belongs to the DEAD box helicase family
CH60_RS13785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH60_RS13795	COG1686	Belongs to the peptidase S11 family
CH60_RS13800	COG0277	FAD linked oxidase domain protein
CH60_RS13820	COG2261	transglycosylase associated protein
CH60_RS13830	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH60_RS13845	COG4807	Protein conserved in bacteria
CH60_RS13865	COG1122	ATPase activity
CH60_RS13885	COG2897	thiosulfate sulfurtransferase activity
CH60_RS13890	COG1732	Glycine betaine
CH60_RS13895	COG1732	Glycine betaine
CH60_RS13900	COG1174	glycine betaine transport
CH60_RS13905	COG1125	glycine betaine transport
CH60_RS13910	COG1174	glycine betaine transport
CH60_RS13915	COG0531	amino acid
CH60_RS13920	COG1982	Orn Lys Arg decarboxylase major
CH60_RS13930	COG0697	spore germination
CH60_RS13955	COG0814	amino acid
CH60_RS13970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH60_RS14000	COG2205	protein histidine kinase activity
CH60_RS14000	COG0784	Response regulator, receiver
CH60_RS14010	COG2198	Histidine kinase
CH60_RS14010	COG0642	Histidine kinase
CH60_RS14015	COG2198	Histidine kinase
CH60_RS14015	COG0642	Histidine kinase
CH60_RS14020	COG2223	nitrite transmembrane transporter activity
CH60_RS14045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH60_RS14090	COG3395	kinase activity
CH60_RS14100	COG1349	DNA-binding transcription factor activity
CH60_RS14105	COG3622	Belongs to the hyi family
CH60_RS14125	COG4386	tail sheath protein
CH60_RS14165	COG3299	homolog of phage Mu protein gp47
CH60_RS14185	COG1737	Transcriptional regulator
CH60_RS14190	COG2723	6-phospho-beta-galactosidase activity
CH60_RS14195	COG3328	transposase activity
CH60_RS14225	COG0513	Belongs to the DEAD box helicase family
CH60_RS14230	COG1309	transcriptional regulator
CH60_RS14240	COG1131	(ABC) transporter
CH60_RS14245	COG0842	Transport permease protein
CH60_RS14250	COG0842	Transport permease protein
CH60_RS14270	COG1902	pentaerythritol trinitrate reductase activity
CH60_RS14290	COG2211	Major facilitator Superfamily
CH60_RS14300	COG2211	Major facilitator Superfamily
CH60_RS14305	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH60_RS14315	COG0583	DNA-binding transcription factor activity
CH60_RS14320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH60_RS14350	COG0670	Belongs to the BI1 family
CH60_RS14355	COG0314	molybdopterin synthase activity
CH60_RS14360	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH60_RS14370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH60_RS14380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH60_RS14405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH60_RS14410	COG4628	conserved protein (DUF2132)
CH60_RS14420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CH60_RS14430	COG2226	methyltransferase
CH60_RS14455	COG0561	phosphatase activity
CH60_RS14465	COG4149	molybdate abc transporter
CH60_RS14470	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH60_RS14480	COG2005	Transcriptional regulator
CH60_RS14480	COG3585	molybdate ion transport
CH60_RS14485	COG1119	ATPase activity
CH60_RS14500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH60_RS14505	COG1085	galactose-1-phosphate uridylyltransferase
CH60_RS14520	COG2017	converts alpha-aldose to the beta-anomer
CH60_RS14535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH60_RS14540	COG1230	cation diffusion facilitator family transporter
CH60_RS14570	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH60_RS14575	COG2885	chlorophyll binding
CH60_RS14585	COG3064	Membrane
CH60_RS14585	COG3064	Membrane
CH60_RS14590	COG0848	biopolymer transport protein
CH60_RS14595	COG0811	peptide transport
CH60_RS14600	COG0824	Thioesterase
CH60_RS14605	COG3790	cyd operon protein YbgE
CH60_RS14610	COG4890	Cyd operon protein YbgT
CH60_RS14615	COG1294	oxidase, subunit
CH60_RS14620	COG1271	oxidase subunit
CH60_RS14630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH60_RS14640	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH60_RS14645	COG0567	Dehydrogenase, E1 component
CH60_RS14655	COG1053	succinate dehydrogenase
CH60_RS14660	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH60_RS14665	COG2009	succinate dehydrogenase
CH60_RS14680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH60_RS14685	COG0497	DNA recombination
CH60_RS14690	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH60_RS14700	COG2867	negative regulation of translational initiation
CH60_RS14720	COG0582	viral genome integration into host DNA
CH60_RS14780	COG3657	addiction module killer protein
CH60_RS14800	COG5001	Diguanylate cyclase
CH60_RS14800	COG3447	MASE1 domain protein
CH60_RS14800	COG5002	protein histidine kinase activity
CH60_RS14810	COG2226	methyltransferase
CH60_RS14815	COG1496	oxidoreductase activity
CH60_RS14840	COG1113	amino acid transport
CH60_RS14875	COG2207	Transcriptional regulator
CH60_RS14885	COG1132	(ABC) transporter
CH60_RS14915	COG2223	nitrite transmembrane transporter activity
CH60_RS14935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH60_RS14960	COG3122	Protein conserved in bacteria
CH60_RS14980	COG0534	Mate efflux family protein
CH60_RS14995	COG4948	Mandelate Racemase Muconate Lactonizing
CH60_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS15010	COG3011	Protein conserved in bacteria
CH60_RS15015	COG2271	Major facilitator Superfamily
CH60_RS15020	COG1388	LysM domain
CH60_RS15020	COG1470	cell adhesion involved in biofilm formation
CH60_RS15035	COG2925	Exonuclease
CH60_RS15040	COG0531	amino acid
CH60_RS15050	COG0371	Dehydrogenase
CH60_RS15055	COG1129	ABC transporter
CH60_RS15060	COG1129	ABC transporter
CH60_RS15075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH60_RS15085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH60_RS15095	COG0131	Imidazoleglycerol-phosphate dehydratase
CH60_RS15095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH60_RS15115	COG0140	phosphoribosyl-ATP diphosphatase activity
CH60_RS15115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH60_RS15125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH60_RS15130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH60_RS15145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH60_RS15150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH60_RS15155	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH60_RS15160	COG1120	ATPase activity
CH60_RS15175	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH60_RS15180	COG0076	glutamate decarboxylase activity
CH60_RS15185	COG4114	ferric iron reductase
CH60_RS15190	COG1253	flavin adenine dinucleotide binding
CH60_RS15195	COG2982	Protein involved in outer membrane biogenesis
CH60_RS15210	COG0489	protein tyrosine kinase activity
CH60_RS15245	COG2814	Major facilitator Superfamily
CH60_RS15255	COG1346	cytolysis
CH60_RS15270	COG2949	membrane
CH60_RS15275	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH60_RS15290	COG2311	Membrane
CH60_RS15300	COG0477	Major facilitator Superfamily
CH60_RS15305	COG0583	DNA-binding transcription factor activity
CH60_RS15335	COG1136	(ABC) transporter
CH60_RS15345	COG0303	'Molybdopterin
CH60_RS15355	COG3328	transposase activity
CH60_RS15365	COG0488	(ABC) transporter
CH60_RS15500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH60_RS15505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH60_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS15520	COG1024	Enoyl-CoA hydratase
CH60_RS15530	COG3425	synthase
CH60_RS15535	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS15540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH60_RS15545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH60_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS15590	COG2920	part of a sulfur-relay system
CH60_RS15610	COG1832	CoA-binding protein
CH60_RS15625	COG0210	DNA helicase
CH60_RS15630	COG3304	Inner membrane component domain
CH60_RS15635	COG1289	transmembrane transporter activity
CH60_RS15640	COG3070	regulator of competence-specific genes
CH60_RS15670	COG1061	Type III restriction enzyme res subunit
CH60_RS15675	COG1187	pseudouridine synthase activity
CH60_RS15680	COG2814	Major facilitator Superfamily
CH60_RS15690	COG4172	Belongs to the ABC transporter superfamily
CH60_RS15695	COG4239	(ABC) transporter, permease
CH60_RS15700	COG4174	ABC transporter (Permease)
CH60_RS15705	COG4166	transmembrane transport
CH60_RS15710	COG2200	EAL domain
CH60_RS15715	COG0791	NLP P60 protein
CH60_RS15720	COG0671	phosphoesterase, PA-phosphatase related
CH60_RS15725	COG0523	cobalamin synthesis protein
CH60_RS15735	COG2186	Transcriptional regulator
CH60_RS15740	COG0246	Mannitol dehydrogenase
CH60_RS15765	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS15800	COG1129	ABC transporter
CH60_RS15810	COG0494	nUDIX hydrolase
CH60_RS15820	COG1105	Belongs to the carbohydrate kinase PfkB family
CH60_RS15825	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH60_RS15825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH60_RS15825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH60_RS15830	COG3710	Transcriptional regulator
CH60_RS15845	COG3121	Chaperone
CH60_RS15850	COG3188	usher protein
CH60_RS15870	COG0435	Glutathione S-transferase
CH60_RS15875	COG2259	Doxx family
CH60_RS15885	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH60_RS15890	COG4575	ribosome binding
CH60_RS15910	COG0586	Pfam SNARE associated Golgi protein
CH60_RS15925	COG2271	Major facilitator Superfamily
CH60_RS15945	COG2721	sulfolactate sulfo-lyase activity
CH60_RS15965	COG0673	inositol 2-dehydrogenase activity
CH60_RS15970	COG1451	nucleotide metabolic process
CH60_RS15985	COG1902	pentaerythritol trinitrate reductase activity
CH60_RS15985	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH60_RS15990	COG3247	response to pH
CH60_RS16010	COG4245	von Willebrand factor, type A
CH60_RS16025	COG4245	von Willebrand factor, type A
CH60_RS16030	COG2831	hemolysin activation secretion protein
CH60_RS16035	COG3210	domain, Protein
CH60_RS16060	COG3210	domain, Protein
CH60_RS16065	COG3210	domain, Protein
CH60_RS16085	COG3842	ATPase activity
CH60_RS16090	COG3459	Glycosyltransferase 36 associated
CH60_RS16095	COG1609	Transcriptional regulator
CH60_RS16100	COG2182	Extracellular solute-binding protein
CH60_RS16110	COG0395	ABC-type sugar transport system, permease component
CH60_RS16130	COG1289	transmembrane transporter activity
CH60_RS16155	COG0436	Aminotransferase
CH60_RS16175	COG0251	oxidation-reduction process
CH60_RS16245	COG3328	transposase activity
CH60_RS16270	COG0358	DNA primase activity
CH60_RS16275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CH60_RS16290	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH60_RS16305	COG4991	sh3 domain protein
CH60_RS16310	COG3025	triphosphatase activity
CH60_RS16325	COG0531	amino acid
CH60_RS16345	COG3384	dioxygenase
CH60_RS16350	COG0754	glutathionylspermidine amidase activity
CH60_RS16365	COG1538	Outer membrane efflux protein
CH60_RS16370	COG0494	nUDIX hydrolase
CH60_RS16375	COG3151	Protein conserved in bacteria
CH60_RS16380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH60_RS16385	COG3150	esterase
CH60_RS16395	COG0583	DNA-binding transcription factor activity
CH60_RS16400	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH60_RS16405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH60_RS16415	COG2132	Multicopper oxidase
CH60_RS16425	COG0656	L-ascorbic acid biosynthetic process
CH60_RS16435	COG1979	alcohol dehydrogenase
CH60_RS16440	COG2207	Transcriptional regulator
CH60_RS16445	COG0586	Pfam SNARE associated Golgi protein
CH60_RS16450	COG0626	cystathionine gamma-synthase activity
CH60_RS16455	COG0811	peptide transport
CH60_RS16460	COG0848	biopolymer transport protein
CH60_RS16510	COG4964	Belongs to the GSP D family
CH60_RS16515	COG4964	Belongs to the GSP D family
CH60_RS16550	COG4592	Periplasmic binding protein
CH60_RS16570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH60_RS16575	COG1684	flagellar biosynthetic protein fliR
CH60_RS16580	COG1987	bacterial-type flagellum assembly
CH60_RS16605	COG1677	Flagellar hook-basal body complex protein FliE
CH60_RS16645	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH60_RS16650	COG1815	bacterial-type flagellum-dependent cell motility
CH60_RS16655	COG1558	bacterial-type flagellum-dependent cell motility
CH60_RS16660	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH60_RS16665	COG1749	Flagellar hook protein flgE
CH60_RS16670	COG4787	bacterial-type flagellum-dependent cell motility
CH60_RS16675	COG4786	Flagellar basal body rod
CH60_RS16685	COG1706	bacterial-type flagellum-dependent cell motility
CH60_RS16695	COG1256	bacterial-type flagellum assembly
CH60_RS16715	COG3710	Transcriptional regulator
CH60_RS16745	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CH60_RS16770	COG1191	sigma factor activity
CH60_RS16775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH60_RS16825	COG2801	Transposase and inactivated derivatives
CH60_RS16885	COG1175	transmembrane transport
CH60_RS16890	COG3833	ABC-type maltose transport systems, permease component
CH60_RS16905	COG0527	aspartate kinase activity
CH60_RS16925	COG1414	Transcriptional regulator
CH60_RS16935	COG2224	Isocitrate lyase
CH60_RS16940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH60_RS16955	COG3328	transposase activity
CH60_RS17000	COG0151	Belongs to the GarS family
CH60_RS17020	COG1515	deoxyribonuclease V activity
CH60_RS17060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH60_RS17115	COG0250	Participates in transcription elongation, termination and antitermination
CH60_RS17170	COG3119	arylsulfatase activity
CH60_RS17175	COG1349	DNA-binding transcription factor activity
CH60_RS17185	COG2222	sugar isomerase
CH60_RS17190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH60_RS17195	COG3715	PTS system
CH60_RS17200	COG3716	PTS system mannose fructose sorbose family IID component
CH60_RS17205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH60_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
CH60_RS17225	COG0641	radical SAM
CH60_RS17230	COG3119	arylsulfatase activity
CH60_RS17260	COG2271	Major facilitator Superfamily
CH60_RS17280	COG1263	PTS System
CH60_RS17280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH60_RS17285	COG1874	Beta-galactosidase
CH60_RS17290	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH60_RS17295	COG3833	ABC-type maltose transport systems, permease component
CH60_RS17300	COG1175	transmembrane transport
CH60_RS17305	COG2182	Extracellular solute-binding protein
CH60_RS17315	COG1129	ABC transporter
CH60_RS17320	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS17325	COG1879	ABC-type sugar transport system periplasmic component
CH60_RS17335	COG0791	NLP P60 protein
CH60_RS17340	COG1695	Transcriptional regulator
CH60_RS17435	COG2944	sequence-specific DNA binding
CH60_RS17465	COG0582	viral genome integration into host DNA
CH60_RS17485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH60_RS17490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH60_RS17495	COG4974	Belongs to the 'phage' integrase family
CH60_RS17500	COG0716	FMN binding
CH60_RS17505	COG4452	Inner membrane protein CreD
CH60_RS17510	COG2205	protein histidine kinase activity
CH60_RS17515	COG0745	RESPONSE REGULATOR receiver
CH60_RS17540	COG1272	protein, Hemolysin III
CH60_RS17550	COG5295	Hep Hag repeat protein
CH60_RS17580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH60_RS17585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH60_RS17590	COG0006	proline dipeptidase activity
CH60_RS17605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH60_RS17610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH60_RS17645	COG0191	fructose-bisphosphate aldolase activity
CH60_RS17665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH60_RS17670	COG0501	Belongs to the peptidase M48B family
CH60_RS17680	COG1166	arginine decarboxylase activity
CH60_RS17695	COG2356	endonuclease I
CH60_RS17700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH60_RS17705	COG0189	ligase activity
CH60_RS17720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH60_RS17730	COG2805	Type II/IV secretion system protein
CH60_RS17735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH60_RS17740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH60_RS17745	COG0762	integral membrane protein
CH60_RS17755	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH60_RS17760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH60_RS17770	COG3064	Membrane
CH60_RS17770	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH60_RS17770	COG1073	alpha beta
CH60_RS17790	COG3171	Protein conserved in bacteria
CH60_RS17800	COG1194	a g-specific adenine glycosylase
CH60_RS17820	COG4774	siderophore transport
CH60_RS17825	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS17830	COG1129	ABC transporter
CH60_RS17835	COG1879	ABC-type sugar transport system periplasmic component
CH60_RS17840	COG1982	Orn Lys Arg decarboxylase major
CH60_RS17975	COG3916	Acyl-homoserine-lactone synthase
CH60_RS17980	COG2771	luxR family
CH60_RS18030	COG2211	Major facilitator Superfamily
CH60_RS18045	COG0471	metal ion transport
CH60_RS18060	COG3209	COG3209 Rhs family protein
CH60_RS18070	COG3501	Rhs element vgr protein
CH60_RS18090	COG2610	gluconate transmembrane transporter activity
CH60_RS18105	COG1132	(ABC) transporter
CH60_RS18110	COG1132	(ABC) transporter
CH60_RS18110	COG2375	cellular response to nickel ion
CH60_RS18135	COG3433	isochorismatase activity
CH60_RS18135	COG2226	methyltransferase
CH60_RS18135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH60_RS18145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH60_RS18145	COG3433	isochorismatase activity
CH60_RS18145	COG2226	methyltransferase
CH60_RS18155	COG4771	TonB-dependent receptor
CH60_RS18180	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH60_RS18185	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH60_RS18225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH60_RS18230	COG5001	Diguanylate cyclase
CH60_RS18235	COG2801	Transposase and inactivated derivatives
CH60_RS18310	COG3501	Rhs element vgr protein
CH60_RS18355	COG3501	Rhs element vgr protein
CH60_RS18365	COG3209	COG3209 Rhs family protein
CH60_RS18380	COG0673	inositol 2-dehydrogenase activity
CH60_RS18385	COG1917	Cupin 2, conserved barrel domain protein
CH60_RS18385	COG2207	Transcriptional regulator
CH60_RS18390	COG1869	D-ribose catabolic process
CH60_RS18395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH60_RS18400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH60_RS18405	COG0431	NADPH-dependent FMN reductase
CH60_RS18420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH60_RS18430	COG3077	Addiction module antitoxin, RelB DinJ family
CH60_RS18435	COG2252	PERMEase
CH60_RS18440	COG0025	NhaP-type Na H and K H
CH60_RS18450	COG1560	Kdo2-lipid A biosynthetic process
CH60_RS18460	COG1129	ABC transporter
CH60_RS18465	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS18475	COG1069	ribulokinase activity
CH60_RS18485	COG0625	glutathione transferase activity
CH60_RS18510	COG1278	Cold shock
CH60_RS18515	COG1278	Cold shock
CH60_RS18525	COG3133	Outer membrane lipoprotein
CH60_RS18530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH60_RS18540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH60_RS18560	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH60_RS18565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH60_RS18575	COG4145	pantothenate transmembrane transporter activity
CH60_RS18580	COG3924	membrane
CH60_RS18585	COG0439	Biotin carboxylase
CH60_RS18590	COG0511	ligase activity, forming carbon-carbon bonds
CH60_RS18605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH60_RS18610	COG0604	alcohol dehydrogenase
CH60_RS18615	COG2199	diguanylate cyclase activity
CH60_RS18615	COG2200	EAL domain
CH60_RS18620	COG1077	Cell shape determining protein MreB Mrl
CH60_RS18625	COG1792	Involved in formation and maintenance of cell shape
CH60_RS18630	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH60_RS18635	COG0424	maF-like protein
CH60_RS18640	COG1530	ribonuclease E activity
CH60_RS18645	COG3164	Protein of unknown function
CH60_RS18650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH60_RS18655	COG0312	modulator of DNA gyrase
CH60_RS18710	COG0583	DNA-binding transcription factor activity
CH60_RS18730	COG1012	belongs to the aldehyde dehydrogenase family
CH60_RS18745	COG2732	(Barnase) inhibitor
CH60_RS18755	COG0312	modulator of DNA gyrase
CH60_RS18765	COG3783	Cytochrome b(562)
CH60_RS18770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH60_RS18775	COG0366	Alpha amylase catalytic
CH60_RS18780	COG1263	PTS System
CH60_RS18780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH60_RS18785	COG1609	Transcriptional regulator
CH60_RS18810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH60_RS18830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH60_RS18835	COG1137	ATPase activity
CH60_RS18840	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH60_RS18845	COG3117	lipopolysaccharide transmembrane transporter activity
CH60_RS18850	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH60_RS18855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH60_RS18855	COG0517	IMP dehydrogenase activity
CH60_RS18860	COG0530	calcium, potassium:sodium antiporter activity
CH60_RS18865	COG1127	ABC transporter
CH60_RS18870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH60_RS18875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH60_RS18880	COG2854	intermembrane phospholipid transfer
CH60_RS18885	COG3113	response to antibiotic
CH60_RS18890	COG5007	Belongs to the BolA IbaG family
CH60_RS18900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH60_RS18915	COG0473	3-isopropylmalate dehydrogenase activity
CH60_RS18945	COG2814	Major facilitator Superfamily
CH60_RS18965	COG4143	(ABC) transporter
CH60_RS18970	COG1178	ABC-type Fe3 transport system permease component
CH60_RS18975	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CH60_RS18980	COG0586	Pfam SNARE associated Golgi protein
CH60_RS18985	COG0417	DNA replication proofreading
CH60_RS19005	COG2885	chlorophyll binding
CH60_RS19005	COG3047	cAMP biosynthetic process
CH60_RS19090	COG0564	pseudouridine synthase activity
CH60_RS19095	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH60_RS19145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH60_RS19155	COG2966	Psort location CytoplasmicMembrane, score
CH60_RS19160	COG1280	lysine exporter protein (LysE YggA)
CH60_RS19165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH60_RS19200	COG1047	Peptidyl-prolyl cis-trans
CH60_RS19215	COG0196	riboflavin kinase activity
CH60_RS19230	COG0583	DNA-binding transcription factor activity
CH60_RS19250	COG1584	GPR1 FUN34 yaaH family protein
CH60_RS19265	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH60_RS19295	COG0745	RESPONSE REGULATOR receiver
CH60_RS19300	COG3045	CreA protein
CH60_RS19305	COG3708	Transcriptional regulator
CH60_RS19305	COG2207	Transcriptional regulator
CH60_RS19320	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH60_RS19325	COG0741	lytic transglycosylase activity
CH60_RS19340	COG2199	diguanylate cyclase activity
CH60_RS19345	COG2885	chlorophyll binding
CH60_RS19350	COG0488	(ABC) transporter
CH60_RS19370	COG0560	Phosphoserine phosphatase
CH60_RS19375	COG3726	membrane protein affecting hemolysin expression
CH60_RS19400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH60_RS19405	COG0084	hydrolase, TatD family'
CH60_RS19410	COG4667	esterase of the alpha-beta hydrolase superfamily
CH60_RS19420	COG2823	Periplasmic or secreted lipoprotein
CH60_RS19430	COG0456	acetyltransferase
CH60_RS19435	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH60_RS19480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH60_RS19485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH60_RS19505	COG0859	PFAM glycosyl transferase family 9
CH60_RS19515	COG2390	Transcriptional regulator
CH60_RS19560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH60_RS19560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH60_RS19560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH60_RS19565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH60_RS19570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH60_RS19575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH60_RS19580	COG2207	Transcriptional regulator
CH60_RS19590	COG4269	membrane
CH60_RS19640	COG2963	transposase activity
CH60_RS19655	COG1401	restriction endodeoxyribonuclease activity
CH60_RS19675	COG0494	nUDIX hydrolase
CH60_RS19700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH60_RS19705	COG0849	cell division
CH60_RS19710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH60_RS19730	COG0772	Belongs to the SEDS family
CH60_RS19745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH60_RS19750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH60_RS19755	COG0768	penicillin binding
CH60_RS19760	COG3116	cell division
CH60_RS19780	COG1609	Transcriptional regulator
CH60_RS19800	COG0028	Belongs to the TPP enzyme family
CH60_RS19810	COG1022	Amp-dependent synthetase and ligase
CH60_RS19840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH60_RS19845	COG3105	Protein conserved in bacteria
CH60_RS19850	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH60_RS19870	COG0625	glutathione transferase activity
CH60_RS19875	COG2969	positive regulation of protein catabolic process
CH60_RS19885	COG0493	'glutamate synthase
CH60_RS19890	COG0070	glutamate synthase
CH60_RS19890	COG0069	glutamate synthase activity
CH60_RS19890	COG0067	glutamate synthase
CH60_RS19895	COG1242	4 iron, 4 sulfur cluster binding
CH60_RS19905	COG0784	Response regulator, receiver
CH60_RS19905	COG2198	Histidine kinase
CH60_RS19905	COG5002	protein histidine kinase activity
CH60_RS19915	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH60_RS19925	COG2823	Periplasmic or secreted lipoprotein
CH60_RS19945	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH60_RS19950	COG1741	Belongs to the pirin family
CH60_RS19955	COG0583	DNA-binding transcription factor activity
CH60_RS19960	COG0435	Glutathione S-transferase
CH60_RS19985	COG0805	protein transport
CH60_RS19995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH60_RS20015	COG1322	Protein conserved in bacteria
CH60_RS20020	COG0586	Pfam SNARE associated Golgi protein
CH60_RS20025	COG1966	Carbon starvation protein
CH60_RS20040	COG0412	Dienelactone hydrolase
CH60_RS20050	COG0583	DNA-binding transcription factor activity
CH60_RS20055	COG0697	spore germination
CH60_RS20060	COG0679	Auxin Efflux Carrier
CH60_RS20065	COG0584	glycerophosphoryl diester phosphodiesterase
CH60_RS20125	COG0410	ABC transporter
CH60_RS20135	COG4177	L-phenylalanine transmembrane transporter activity
CH60_RS20145	COG0683	leucine binding
CH60_RS20170	COG2177	Part of the ABC transporter FtsEX involved in
CH60_RS20175	COG2884	Cell division ATP-binding protein ftsE
CH60_RS20180	COG0552	protein localization to endoplasmic reticulum
CH60_RS20180	COG0552	protein localization to endoplasmic reticulum
CH60_RS20190	COG0742	ribosomal rna small subunit methyltransferase
CH60_RS20195	COG3776	membrane
CH60_RS20210	COG3714	YhhN family
CH60_RS20225	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH60_RS20235	COG0247	lactate metabolic process
CH60_RS20245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH60_RS20255	COG0584	glycerophosphoryl diester phosphodiesterase
CH60_RS20265	COG0561	phosphatase activity
CH60_RS20270	COG2267	carboxylic ester hydrolase activity
CH60_RS20275	COG1280	lysine exporter protein (LysE YggA)
CH60_RS20280	COG1280	lysine exporter protein (LysE YggA)
CH60_RS20285	COG0514	ATP-dependent DNA helicase (RecQ)
CH60_RS20290	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH60_RS20295	COG2050	protein possibly involved in aromatic compounds catabolism
CH60_RS20310	COG5564	TIM-barrel signal transduction protein
CH60_RS20315	COG5441	Belongs to the UPF0261 family
CH60_RS20325	COG0210	DNA helicase
CH60_RS20330	COG1011	Hydrolase
CH60_RS20335	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH60_RS20340	COG3159	Protein conserved in bacteria
CH60_RS20360	COG3072	Adenylate cyclase
CH60_RS20370	COG1587	Uroporphyrinogen-III synthase
CH60_RS20375	COG2959	enzyme of heme biosynthesis
CH60_RS20380	COG3071	HemY protein
CH60_RS20410	COG1113	amino acid transport
CH60_RS20430	COG2244	polysaccharide biosynthetic process
CH60_RS20435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH60_RS20440	COG0456	acetyltransferase
CH60_RS20445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH60_RS20450	COG1088	dTDP-glucose 4,6-dehydratase activity
CH60_RS20455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH60_RS20460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH60_RS20465	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH60_RS20470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH60_RS20475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH60_RS20480	COG3118	belongs to the thioredoxin family
CH60_RS20505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH60_RS20525	COG3121	Chaperone
CH60_RS20540	COG3121	Chaperone
CH60_RS20580	COG0583	DNA-binding transcription factor activity
CH60_RS20620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH60_RS20625	COG3978	acetolactate synthase activity
CH60_RS20640	COG3085	chromosome segregation
CH60_RS20650	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS20655	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH60_RS20660	COG1129	ABC transporter
CH60_RS20665	COG1879	ABC-type sugar transport system periplasmic component
CH60_RS20745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH60_RS20745	COG0678	peroxiredoxin activity
CH60_RS20750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH60_RS20775	COG1629	transport
CH60_RS20795	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH60_RS20850	COG3276	selenocysteine insertion sequence binding
CH60_RS20855	COG3276	selenocysteine insertion sequence binding
CH60_RS20870	COG2864	formate dehydrogenase
CH60_RS20875	COG0437	4 iron, 4 sulfur cluster binding
CH60_RS20880	COG0243	molybdopterin cofactor binding
CH60_RS20880	COG3383	formate dehydrogenase (NAD+) activity
CH60_RS20885	COG0243	molybdopterin cofactor binding
CH60_RS20885	COG3383	formate dehydrogenase (NAD+) activity
CH60_RS20895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH60_RS20920	COG3722	fumarate hydratase activity
CH60_RS20930	COG2213	PTS system mannitol-specific
CH60_RS20930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH60_RS20950	COG2818	Glycosylase
CH60_RS20960	COG2885	chlorophyll binding
CH60_RS20975	COG0366	Alpha amylase catalytic
CH60_RS20985	COG3977	Valine--pyruvate aminotransferase
CH60_RS21005	COG5645	(Lipo)protein
CH60_RS21010	COG0823	Involved in the tonB-independent uptake of proteins
CH60_RS21015	COG0823	Involved in the tonB-independent uptake of proteins
CH60_RS21020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH60_RS21025	COG2423	ornithine cyclodeaminase activity
CH60_RS21035	COG2801	Transposase and inactivated derivatives
CH60_RS21040	COG0561	phosphatase activity
CH60_RS21045	COG0187	DNA topoisomerase II activity
CH60_RS21060	COG0592	DNA-directed DNA polymerase activity
CH60_RS21070	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH60_RS21080	COG0706	membrane insertase activity
CH60_RS21105	COG2252	PERMEase
CH60_RS21110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH60_RS21115	COG0765	amino acid transport
CH60_RS21120	COG0765	amino acid transport
CH60_RS21125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH60_RS21135	COG0704	Plays a role in the regulation of phosphate uptake
CH60_RS21145	COG0581	inorganic phosphate transmembrane transporter activity
CH60_RS21150	COG0573	inorganic phosphate transmembrane transporter activity
CH60_RS21155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH60_RS21210	COG3312	ion transport
CH60_RS21225	COG0716	FMN binding
CH60_RS21230	COG1522	sequence-specific DNA binding
CH60_RS21260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH60_RS21270	COG0477	Major facilitator Superfamily
CH60_RS21275	COG2186	Transcriptional regulator
CH60_RS21305	COG3328	transposase activity
CH60_RS21310	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH60_RS21320	COG3084	Protein conserved in bacteria
CH60_RS21325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH60_RS21330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH60_RS21335	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH60_RS21335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH60_RS21350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH60_RS21360	COG3852	Histidine kinase
CH60_RS21365	COG0174	glutamine synthetase
CH60_RS21380	COG1011	Hydrolase
CH60_RS21405	COG0456	acetyltransferase
CH60_RS21410	COG2982	Protein involved in outer membrane biogenesis
CH60_RS21415	COG2233	PERMEase
CH60_RS21420	COG0786	glutamate:sodium symporter activity
CH60_RS21425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH60_RS21430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH60_RS21435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH60_RS21455	COG2860	membrane
CH60_RS21460	COG1561	YicC-like family, N-terminal region
CH60_RS21485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH60_RS21520	COG1519	Transferase
CH60_RS21525	COG0859	PFAM glycosyl transferase family 9
CH60_RS21530	COG0859	PFAM glycosyl transferase family 9
CH60_RS21540	COG0156	8-amino-7-oxononanoate synthase activity
CH60_RS21555	COG4942	peptidase
CH60_RS21565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH60_RS21570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH60_RS21590	COG1045	serine acetyltransferase
CH60_RS21595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH60_RS21600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH60_RS21600	COG2169	Transcriptional regulator
CH60_RS21605	COG2205	protein histidine kinase activity
CH60_RS21610	COG0745	RESPONSE REGULATOR receiver
CH60_RS21615	COG3678	ATP-independent chaperone mediated protein folding
CH60_RS21635	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH60_RS21645	COG0471	metal ion transport
CH60_RS21650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH60_RS21655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH60_RS21660	COG0583	DNA-binding transcription factor activity
CH60_RS21675	COG3152	Membrane
CH60_RS21685	COG1494	fructose-1,6-bisphosphatase
CH60_RS21690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH60_RS21695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH60_RS21745	COG1575	Belongs to the MenA family. Type 1 subfamily
CH60_RS21760	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH60_RS21765	COG1609	Transcriptional regulator
CH60_RS21775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH60_RS21785	COG4682	membrane
CH60_RS21800	COG0626	cystathionine gamma-synthase activity
CH60_RS21805	COG0527	aspartate kinase activity
CH60_RS21805	COG0460	homoserine dehydrogenase
CH60_RS21815	COG2801	Transposase and inactivated derivatives
CH60_RS21820	COG2801	Transposase and inactivated derivatives
CH60_RS21835	COG3274	enterobacterial common antigen metabolic process
CH60_RS21855	COG3121	Chaperone
CH60_RS21865	COG1070	Carbohydrate kinase
CH60_RS21875	COG4213	ABC transporter substrate-binding protein
CH60_RS21885	COG4214	carbohydrate transport
CH60_RS21890	COG1609	Transcriptional regulator
CH60_RS21890	COG2207	Transcriptional regulator
CH60_RS21895	COG0582	viral genome integration into host DNA
CH60_RS21935	COG4604	ABC transporter, ATP-binding protein
CH60_RS21940	COG4605	iron ion homeostasis
CH60_RS21950	COG4607	ABC-type enterochelin transport system periplasmic component
CH60_RS21980	COG2986	histidine ammonia-lyase
CH60_RS22010	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH60_RS22035	COG1739	Uncharacterized protein family UPF0029
CH60_RS22040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH60_RS22045	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH60_RS22075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH60_RS22105	COG2801	Transposase and inactivated derivatives
CH60_RS22125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH60_RS22130	COG0058	SHG alpha-glucan phosphorylase activity
CH60_RS22155	COG3275	phosphorelay sensor kinase activity
CH60_RS22185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH60_RS22190	COG2095	MarC family integral membrane protein
CH60_RS22210	COG3265	gluconokinase activity
CH60_RS22215	COG2610	gluconate transmembrane transporter activity
CH60_RS22220	COG1609	Transcriptional regulator
CH60_RS22245	COG2801	Transposase and inactivated derivatives