locus-tag	class	description
YPSIP31758_RS00135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPSIP31758_RS00135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPSIP31758_RS00225	COG1217	gtp-binding protein TYPA
YPSIP31758_RS00805	COG2205	protein histidine kinase activity
YPSIP31758_RS00965	COG1575	Belongs to the MenA family. Type 1 subfamily
YPSIP31758_RS01000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPSIP31758_RS01035	COG0527	aspartate kinase activity
YPSIP31758_RS01035	COG0460	homoserine dehydrogenase
YPSIP31758_RS01270	COG0716	FMN binding
YPSIP31758_RS01275	COG1522	sequence-specific DNA binding
YPSIP31758_RS01305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPSIP31758_RS01315	COG0477	Major facilitator Superfamily
YPSIP31758_RS01320	COG2186	Transcriptional regulator
YPSIP31758_RS01350	COG3328	transposase activity
YPSIP31758_RS01355	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPSIP31758_RS01365	COG3084	Protein conserved in bacteria
YPSIP31758_RS01370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPSIP31758_RS01375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPSIP31758_RS01380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPSIP31758_RS01380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPSIP31758_RS01400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPSIP31758_RS01410	COG3852	Histidine kinase
YPSIP31758_RS01415	COG0174	glutamine synthetase
YPSIP31758_RS01430	COG1011	Hydrolase
YPSIP31758_RS01445	COG0456	acetyltransferase
YPSIP31758_RS01450	COG2982	Protein involved in outer membrane biogenesis
YPSIP31758_RS01455	COG2233	PERMEase
YPSIP31758_RS01460	COG0786	glutamate:sodium symporter activity
YPSIP31758_RS01465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPSIP31758_RS01470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPSIP31758_RS01475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPSIP31758_RS01480	COG1758	RNA polymerase activity
YPSIP31758_RS01495	COG2860	membrane
YPSIP31758_RS01530	COG3157	Type VI secretion system effector, Hcp
YPSIP31758_RS01570	COG1561	YicC-like family, N-terminal region
YPSIP31758_RS01595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPSIP31758_RS01630	COG1519	Transferase
YPSIP31758_RS01635	COG0859	PFAM glycosyl transferase family 9
YPSIP31758_RS01640	COG0859	PFAM glycosyl transferase family 9
YPSIP31758_RS01650	COG0156	8-amino-7-oxononanoate synthase activity
YPSIP31758_RS01660	COG2861	carbohydrate metabolic process
YPSIP31758_RS01665	COG4942	peptidase
YPSIP31758_RS01675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPSIP31758_RS01680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPSIP31758_RS01700	COG1045	serine acetyltransferase
YPSIP31758_RS01705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPSIP31758_RS01710	COG2169	Transcriptional regulator
YPSIP31758_RS01710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPSIP31758_RS01715	COG2205	protein histidine kinase activity
YPSIP31758_RS01720	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS01725	COG3678	ATP-independent chaperone mediated protein folding
YPSIP31758_RS01745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPSIP31758_RS01755	COG0471	metal ion transport
YPSIP31758_RS01760	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPSIP31758_RS01765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPSIP31758_RS01770	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS01785	COG3152	Membrane
YPSIP31758_RS01795	COG1494	fructose-1,6-bisphosphatase
YPSIP31758_RS01800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPSIP31758_RS01805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPSIP31758_RS01850	COG1575	Belongs to the MenA family. Type 1 subfamily
YPSIP31758_RS01865	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPSIP31758_RS01870	COG1609	Transcriptional regulator
YPSIP31758_RS01880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPSIP31758_RS01890	COG4682	membrane
YPSIP31758_RS01900	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YPSIP31758_RS01905	COG0626	cystathionine gamma-synthase activity
YPSIP31758_RS01910	COG0527	aspartate kinase activity
YPSIP31758_RS01910	COG0460	homoserine dehydrogenase
YPSIP31758_RS01950	COG1629	transport
YPSIP31758_RS01975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPSIP31758_RS01980	COG0678	peroxiredoxin activity
YPSIP31758_RS01980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPSIP31758_RS02060	COG1879	ABC-type sugar transport system periplasmic component
YPSIP31758_RS02065	COG1129	ABC transporter
YPSIP31758_RS02070	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS02075	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS02085	COG3085	chromosome segregation
YPSIP31758_RS02090	COG0606	chelatase, subunit chli
YPSIP31758_RS02100	COG3978	acetolactate synthase activity
YPSIP31758_RS02105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPSIP31758_RS02135	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS02170	COG3121	Chaperone
YPSIP31758_RS02185	COG3121	Chaperone
YPSIP31758_RS02205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPSIP31758_RS02230	COG3118	belongs to the thioredoxin family
YPSIP31758_RS02235	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPSIP31758_RS02250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPSIP31758_RS02255	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPSIP31758_RS02260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPSIP31758_RS02265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPSIP31758_RS02270	COG1088	dTDP-glucose 4,6-dehydratase activity
YPSIP31758_RS02275	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPSIP31758_RS02280	COG0456	acetyltransferase
YPSIP31758_RS02285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPSIP31758_RS02290	COG2244	polysaccharide biosynthetic process
YPSIP31758_RS02310	COG1113	amino acid transport
YPSIP31758_RS02335	COG3071	HemY protein
YPSIP31758_RS02340	COG2959	enzyme of heme biosynthesis
YPSIP31758_RS02345	COG1587	Uroporphyrinogen-III synthase
YPSIP31758_RS02355	COG3072	Adenylate cyclase
YPSIP31758_RS02380	COG3159	Protein conserved in bacteria
YPSIP31758_RS02385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPSIP31758_RS02390	COG1011	Hydrolase
YPSIP31758_RS02395	COG0210	DNA helicase
YPSIP31758_RS02405	COG5441	Belongs to the UPF0261 family
YPSIP31758_RS02410	COG5564	TIM-barrel signal transduction protein
YPSIP31758_RS02425	COG2050	protein possibly involved in aromatic compounds catabolism
YPSIP31758_RS02430	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPSIP31758_RS02435	COG0514	ATP-dependent DNA helicase (RecQ)
YPSIP31758_RS02440	COG1280	lysine exporter protein (LysE YggA)
YPSIP31758_RS02445	COG1280	lysine exporter protein (LysE YggA)
YPSIP31758_RS02450	COG2267	carboxylic ester hydrolase activity
YPSIP31758_RS02455	COG0561	phosphatase activity
YPSIP31758_RS02465	COG0584	glycerophosphoryl diester phosphodiesterase
YPSIP31758_RS02470	COG2271	Major facilitator Superfamily
YPSIP31758_RS02475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPSIP31758_RS02485	COG0247	lactate metabolic process
YPSIP31758_RS02495	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPSIP31758_RS02510	COG3714	YhhN family
YPSIP31758_RS02525	COG3776	membrane
YPSIP31758_RS02530	COG0742	ribosomal rna small subunit methyltransferase
YPSIP31758_RS02540	COG0552	protein localization to endoplasmic reticulum
YPSIP31758_RS02540	COG0552	protein localization to endoplasmic reticulum
YPSIP31758_RS02545	COG2884	Cell division ATP-binding protein ftsE
YPSIP31758_RS02550	COG2177	Part of the ABC transporter FtsEX involved in
YPSIP31758_RS02565	COG0683	leucine binding
YPSIP31758_RS02575	COG4177	L-phenylalanine transmembrane transporter activity
YPSIP31758_RS02585	COG0410	ABC transporter
YPSIP31758_RS02645	COG0584	glycerophosphoryl diester phosphodiesterase
YPSIP31758_RS02650	COG0679	Auxin Efflux Carrier
YPSIP31758_RS02655	COG0697	spore germination
YPSIP31758_RS02660	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS02670	COG0412	Dienelactone hydrolase
YPSIP31758_RS02685	COG1966	Carbon starvation protein
YPSIP31758_RS02690	COG0586	Pfam SNARE associated Golgi protein
YPSIP31758_RS02695	COG1322	Protein conserved in bacteria
YPSIP31758_RS02715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPSIP31758_RS02725	COG0805	protein transport
YPSIP31758_RS02770	COG1739	Uncharacterized protein family UPF0029
YPSIP31758_RS02775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPSIP31758_RS02780	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPSIP31758_RS02825	COG3328	transposase activity
YPSIP31758_RS02840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPSIP31758_RS02845	COG2224	Isocitrate lyase
YPSIP31758_RS02855	COG1414	Transcriptional regulator
YPSIP31758_RS02875	COG0527	aspartate kinase activity
YPSIP31758_RS02890	COG3833	ABC-type maltose transport systems, permease component
YPSIP31758_RS02895	COG1175	transmembrane transport
YPSIP31758_RS03010	COG3501	Rhs element vgr protein
YPSIP31758_RS03065	COG3501	Rhs element vgr protein
YPSIP31758_RS03075	COG3209	COG3209 Rhs family protein
YPSIP31758_RS03085	COG3501	Rhs element vgr protein
YPSIP31758_RS03095	COG0673	inositol 2-dehydrogenase activity
YPSIP31758_RS03100	COG2207	Transcriptional regulator
YPSIP31758_RS03105	COG1869	D-ribose catabolic process
YPSIP31758_RS03110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPSIP31758_RS03115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPSIP31758_RS03120	COG0431	NADPH-dependent FMN reductase
YPSIP31758_RS03125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPSIP31758_RS03135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPSIP31758_RS03145	COG3077	Addiction module antitoxin, RelB DinJ family
YPSIP31758_RS03150	COG2252	PERMEase
YPSIP31758_RS03155	COG0025	NhaP-type Na H and K H
YPSIP31758_RS03165	COG1560	Kdo2-lipid A biosynthetic process
YPSIP31758_RS03175	COG1129	ABC transporter
YPSIP31758_RS03180	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS03190	COG1069	ribulokinase activity
YPSIP31758_RS03200	COG0625	glutathione transferase activity
YPSIP31758_RS03215	COG1278	Cold shock
YPSIP31758_RS03220	COG1278	Cold shock
YPSIP31758_RS03225	COG1278	Cold shock
YPSIP31758_RS03235	COG3133	Outer membrane lipoprotein
YPSIP31758_RS03240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPSIP31758_RS03250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPSIP31758_RS03270	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPSIP31758_RS03275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPSIP31758_RS03285	COG4145	pantothenate transmembrane transporter activity
YPSIP31758_RS03290	COG3924	membrane
YPSIP31758_RS03295	COG0439	Biotin carboxylase
YPSIP31758_RS03300	COG0511	ligase activity, forming carbon-carbon bonds
YPSIP31758_RS03320	COG0604	alcohol dehydrogenase
YPSIP31758_RS03325	COG2200	EAL domain
YPSIP31758_RS03325	COG2199	diguanylate cyclase activity
YPSIP31758_RS03330	COG1077	Cell shape determining protein MreB Mrl
YPSIP31758_RS03335	COG1792	Involved in formation and maintenance of cell shape
YPSIP31758_RS03340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPSIP31758_RS03345	COG0424	maF-like protein
YPSIP31758_RS03350	COG1530	ribonuclease E activity
YPSIP31758_RS03355	COG3164	Protein of unknown function
YPSIP31758_RS03360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPSIP31758_RS03365	COG0312	modulator of DNA gyrase
YPSIP31758_RS03425	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS03455	COG2732	(Barnase) inhibitor
YPSIP31758_RS03465	COG0312	modulator of DNA gyrase
YPSIP31758_RS03475	COG3783	Cytochrome b(562)
YPSIP31758_RS03480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPSIP31758_RS03485	COG0366	Alpha amylase catalytic
YPSIP31758_RS03490	COG1263	PTS System
YPSIP31758_RS03490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPSIP31758_RS03495	COG1609	Transcriptional regulator
YPSIP31758_RS03520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPSIP31758_RS03540	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPSIP31758_RS03545	COG1137	ATPase activity
YPSIP31758_RS03550	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPSIP31758_RS03555	COG3117	lipopolysaccharide transmembrane transporter activity
YPSIP31758_RS03560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPSIP31758_RS03565	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPSIP31758_RS03565	COG0517	IMP dehydrogenase activity
YPSIP31758_RS03570	COG0530	calcium, potassium:sodium antiporter activity
YPSIP31758_RS03575	COG1127	ABC transporter
YPSIP31758_RS03580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPSIP31758_RS03585	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPSIP31758_RS03590	COG2854	intermembrane phospholipid transfer
YPSIP31758_RS03595	COG3113	response to antibiotic
YPSIP31758_RS03600	COG5007	Belongs to the BolA IbaG family
YPSIP31758_RS03610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPSIP31758_RS03615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPSIP31758_RS03620	COG3105	Protein conserved in bacteria
YPSIP31758_RS03625	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPSIP31758_RS03645	COG0625	glutathione transferase activity
YPSIP31758_RS03650	COG2969	positive regulation of protein catabolic process
YPSIP31758_RS03660	COG0493	'glutamate synthase
YPSIP31758_RS03665	COG0069	glutamate synthase activity
YPSIP31758_RS03665	COG0070	glutamate synthase
YPSIP31758_RS03665	COG0067	glutamate synthase
YPSIP31758_RS03670	COG1242	4 iron, 4 sulfur cluster binding
YPSIP31758_RS03680	COG2198	Histidine kinase
YPSIP31758_RS03680	COG5002	protein histidine kinase activity
YPSIP31758_RS03680	COG0784	Response regulator, receiver
YPSIP31758_RS03690	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPSIP31758_RS03700	COG2823	Periplasmic or secreted lipoprotein
YPSIP31758_RS03720	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPSIP31758_RS03725	COG1741	Belongs to the pirin family
YPSIP31758_RS03730	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS03735	COG0435	Glutathione S-transferase
YPSIP31758_RS03740	COG2259	Doxx family
YPSIP31758_RS03750	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPSIP31758_RS03755	COG4575	ribosome binding
YPSIP31758_RS03775	COG0586	Pfam SNARE associated Golgi protein
YPSIP31758_RS03790	COG2271	Major facilitator Superfamily
YPSIP31758_RS03810	COG2721	sulfolactate sulfo-lyase activity
YPSIP31758_RS03830	COG0673	inositol 2-dehydrogenase activity
YPSIP31758_RS03835	COG1451	nucleotide metabolic process
YPSIP31758_RS03850	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPSIP31758_RS03850	COG1902	pentaerythritol trinitrate reductase activity
YPSIP31758_RS03855	COG3247	response to pH
YPSIP31758_RS03875	COG4245	von Willebrand factor, type A
YPSIP31758_RS03890	COG4245	von Willebrand factor, type A
YPSIP31758_RS03895	COG2831	hemolysin activation secretion protein
YPSIP31758_RS03920	COG3210	domain, Protein
YPSIP31758_RS03950	COG3210	domain, Protein
YPSIP31758_RS03960	COG3210	domain, Protein
YPSIP31758_RS03980	COG3842	ATPase activity
YPSIP31758_RS03985	COG3459	Glycosyltransferase 36 associated
YPSIP31758_RS03990	COG1609	Transcriptional regulator
YPSIP31758_RS03995	COG2182	Extracellular solute-binding protein
YPSIP31758_RS04005	COG0395	ABC-type sugar transport system, permease component
YPSIP31758_RS04025	COG1289	transmembrane transporter activity
YPSIP31758_RS04050	COG0436	Aminotransferase
YPSIP31758_RS04070	COG0251	oxidation-reduction process
YPSIP31758_RS04110	COG3157	Type VI secretion system effector, Hcp
YPSIP31758_RS04140	COG0358	DNA primase activity
YPSIP31758_RS04145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YPSIP31758_RS04160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPSIP31758_RS04175	COG4991	sh3 domain protein
YPSIP31758_RS04180	COG3025	triphosphatase activity
YPSIP31758_RS04195	COG0531	amino acid
YPSIP31758_RS04215	COG3384	dioxygenase
YPSIP31758_RS04220	COG0754	glutathionylspermidine amidase activity
YPSIP31758_RS04235	COG1538	Outer membrane efflux protein
YPSIP31758_RS04240	COG0494	nUDIX hydrolase
YPSIP31758_RS04245	COG3151	Protein conserved in bacteria
YPSIP31758_RS04250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPSIP31758_RS04255	COG3150	esterase
YPSIP31758_RS04265	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS04270	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPSIP31758_RS04280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPSIP31758_RS04290	COG2132	Multicopper oxidase
YPSIP31758_RS04305	COG0656	L-ascorbic acid biosynthetic process
YPSIP31758_RS04315	COG1979	alcohol dehydrogenase
YPSIP31758_RS04320	COG2207	Transcriptional regulator
YPSIP31758_RS04325	COG0586	Pfam SNARE associated Golgi protein
YPSIP31758_RS04330	COG0626	cystathionine gamma-synthase activity
YPSIP31758_RS04335	COG0811	peptide transport
YPSIP31758_RS04340	COG0848	biopolymer transport protein
YPSIP31758_RS04390	COG4964	Belongs to the GSP D family
YPSIP31758_RS04425	COG3397	chitin binding
YPSIP31758_RS04430	COG3469	chitinase activity
YPSIP31758_RS04455	COG4592	Periplasmic binding protein
YPSIP31758_RS04475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPSIP31758_RS04480	COG1684	flagellar biosynthetic protein fliR
YPSIP31758_RS04485	COG1987	bacterial-type flagellum assembly
YPSIP31758_RS04550	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPSIP31758_RS04555	COG1815	bacterial-type flagellum-dependent cell motility
YPSIP31758_RS04560	COG1558	bacterial-type flagellum-dependent cell motility
YPSIP31758_RS04565	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPSIP31758_RS04570	COG1749	Flagellar hook protein flgE
YPSIP31758_RS04575	COG4787	bacterial-type flagellum-dependent cell motility
YPSIP31758_RS04580	COG4786	Flagellar basal body rod
YPSIP31758_RS04590	COG1706	bacterial-type flagellum-dependent cell motility
YPSIP31758_RS04600	COG1256	bacterial-type flagellum assembly
YPSIP31758_RS04620	COG3710	Transcriptional regulator
YPSIP31758_RS04625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YPSIP31758_RS04630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YPSIP31758_RS04635	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YPSIP31758_RS04660	COG1191	sigma factor activity
YPSIP31758_RS04665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YPSIP31758_RS04695	COG3133	Outer membrane lipoprotein
YPSIP31758_RS04705	COG5001	Diguanylate cyclase
YPSIP31758_RS04705	COG3300	MHYT domain
YPSIP31758_RS04710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPSIP31758_RS04720	COG4282	regulation of fungal-type cell wall biogenesis
YPSIP31758_RS04760	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPSIP31758_RS04765	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPSIP31758_RS04770	COG4771	TonB-dependent receptor
YPSIP31758_RS04780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPSIP31758_RS04780	COG3433	isochorismatase activity
YPSIP31758_RS04780	COG2226	methyltransferase
YPSIP31758_RS04790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPSIP31758_RS04790	COG2226	methyltransferase
YPSIP31758_RS04790	COG3433	isochorismatase activity
YPSIP31758_RS04815	COG2375	cellular response to nickel ion
YPSIP31758_RS04815	COG1132	(ABC) transporter
YPSIP31758_RS04820	COG1132	(ABC) transporter
YPSIP31758_RS04835	COG2610	gluconate transmembrane transporter activity
YPSIP31758_RS04850	COG3501	Rhs element vgr protein
YPSIP31758_RS04860	COG3209	COG3209 Rhs family protein
YPSIP31758_RS04870	COG3209	COG3209 Rhs family protein
YPSIP31758_RS04900	COG0471	metal ion transport
YPSIP31758_RS04905	COG1609	Transcriptional regulator
YPSIP31758_RS04915	COG2211	Major facilitator Superfamily
YPSIP31758_RS04960	COG2771	luxR family
YPSIP31758_RS04965	COG3916	Acyl-homoserine-lactone synthase
YPSIP31758_RS05165	COG2378	regulation of single-species biofilm formation
YPSIP31758_RS05170	COG3596	GTP binding
YPSIP31758_RS05265	COG2885	chlorophyll binding
YPSIP31758_RS05385	COG0582	viral genome integration into host DNA
YPSIP31758_RS05395	COG1982	Orn Lys Arg decarboxylase major
YPSIP31758_RS05400	COG1879	ABC-type sugar transport system periplasmic component
YPSIP31758_RS05405	COG1129	ABC transporter
YPSIP31758_RS05410	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS05415	COG4774	siderophore transport
YPSIP31758_RS05435	COG1194	a g-specific adenine glycosylase
YPSIP31758_RS05445	COG3171	Protein conserved in bacteria
YPSIP31758_RS05460	COG1073	alpha beta
YPSIP31758_RS05460	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPSIP31758_RS05460	COG3064	Membrane
YPSIP31758_RS05465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPSIP31758_RS05480	COG0762	integral membrane protein
YPSIP31758_RS05485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPSIP31758_RS05490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPSIP31758_RS05495	COG2805	Type II/IV secretion system protein
YPSIP31758_RS05505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPSIP31758_RS05520	COG0189	ligase activity
YPSIP31758_RS05525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPSIP31758_RS05530	COG2356	endonuclease I
YPSIP31758_RS05545	COG1166	arginine decarboxylase activity
YPSIP31758_RS05555	COG0501	Belongs to the peptidase M48B family
YPSIP31758_RS05560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPSIP31758_RS05575	COG0191	fructose-bisphosphate aldolase activity
YPSIP31758_RS05610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPSIP31758_RS05615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPSIP31758_RS05630	COG0006	proline dipeptidase activity
YPSIP31758_RS05635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPSIP31758_RS05640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPSIP31758_RS05670	COG5295	Hep Hag repeat protein
YPSIP31758_RS05680	COG1272	protein, Hemolysin III
YPSIP31758_RS05705	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS05710	COG2205	protein histidine kinase activity
YPSIP31758_RS05715	COG4452	Inner membrane protein CreD
YPSIP31758_RS05720	COG0716	FMN binding
YPSIP31758_RS05725	COG4974	Belongs to the 'phage' integrase family
YPSIP31758_RS05730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPSIP31758_RS05735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPSIP31758_RS05755	COG0582	viral genome integration into host DNA
YPSIP31758_RS05785	COG2944	sequence-specific DNA binding
YPSIP31758_RS05880	COG1695	Transcriptional regulator
YPSIP31758_RS05885	COG0791	NLP P60 protein
YPSIP31758_RS05895	COG1879	ABC-type sugar transport system periplasmic component
YPSIP31758_RS05900	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS05905	COG1129	ABC transporter
YPSIP31758_RS05915	COG2182	Extracellular solute-binding protein
YPSIP31758_RS05920	COG1175	transmembrane transport
YPSIP31758_RS05925	COG3833	ABC-type maltose transport systems, permease component
YPSIP31758_RS05930	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPSIP31758_RS05935	COG1874	Beta-galactosidase
YPSIP31758_RS05940	COG1263	PTS System
YPSIP31758_RS05940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPSIP31758_RS05960	COG2271	Major facilitator Superfamily
YPSIP31758_RS05990	COG3119	arylsulfatase activity
YPSIP31758_RS05995	COG0641	radical SAM
YPSIP31758_RS06005	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS06015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPSIP31758_RS06020	COG3716	PTS system mannose fructose sorbose family IID component
YPSIP31758_RS06025	COG3715	PTS system
YPSIP31758_RS06030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPSIP31758_RS06035	COG2222	sugar isomerase
YPSIP31758_RS06045	COG1349	DNA-binding transcription factor activity
YPSIP31758_RS06050	COG3119	arylsulfatase activity
YPSIP31758_RS06080	COG0288	reversible hydration of carbon dioxide
YPSIP31758_RS06100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPSIP31758_RS06165	COG0840	transmembrane signaling receptor activity
YPSIP31758_RS06180	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS06185	COG2814	Major facilitator Superfamily
YPSIP31758_RS06190	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS06200	COG1609	Transcriptional regulator
YPSIP31758_RS06230	COG0667	Aldo Keto reductase
YPSIP31758_RS06295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPSIP31758_RS06305	COG1074	ATP-dependent DNA helicase activity
YPSIP31758_RS06310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPSIP31758_RS06320	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPSIP31758_RS06340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPSIP31758_RS06345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPSIP31758_RS06350	COG2166	iron-sulfur cluster assembly
YPSIP31758_RS06355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPSIP31758_RS06360	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS06365	COG2363	Small membrane protein
YPSIP31758_RS06380	COG1611	Belongs to the LOG family
YPSIP31758_RS06395	COG3098	single-species biofilm formation
YPSIP31758_RS06400	COG0564	pseudouridine synthase activity
YPSIP31758_RS06460	COG0575	Belongs to the CDS family
YPSIP31758_RS06465	COG0750	zinc metalloprotease
YPSIP31758_RS06480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPSIP31758_RS06505	COG0587	DNA-directed DNA polymerase activity
YPSIP31758_RS06515	COG0346	lactoylglutathione lyase activity
YPSIP31758_RS06530	COG4568	rho-dependent transcription termination
YPSIP31758_RS06540	COG4681	YaeQ
YPSIP31758_RS06550	COG3015	lipoprotein NlpE involved in copper resistance
YPSIP31758_RS06560	COG1720	tRNA m6t6A37 methyltransferase activity
YPSIP31758_RS06570	COG1464	Belongs to the NlpA lipoprotein family
YPSIP31758_RS06575	COG2011	ABC-type metal ion transport system permease component
YPSIP31758_RS06585	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPSIP31758_RS06620	COG0656	L-ascorbic acid biosynthetic process
YPSIP31758_RS06635	COG0741	lytic transglycosylase activity
YPSIP31758_RS06635	COG1388	LysM domain
YPSIP31758_RS06645	COG2226	methyltransferase
YPSIP31758_RS06665	COG1953	Uracil, thiamine, allantoin
YPSIP31758_RS06675	COG2113	Glycine betaine
YPSIP31758_RS06680	COG4176	ABC-type proline glycine betaine transport system permease component
YPSIP31758_RS06685	COG4175	Glycine betaine
YPSIP31758_RS06690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPSIP31758_RS06730	COG1278	Cold shock
YPSIP31758_RS06735	COG0747	negative chemotaxis
YPSIP31758_RS06745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPSIP31758_RS06750	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPSIP31758_RS06755	COG1124	(ABC) transporter
YPSIP31758_RS06760	COG0831	urea catabolic process
YPSIP31758_RS06785	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPSIP31758_RS06795	COG4413	Urea transporter
YPSIP31758_RS06800	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPSIP31758_RS06815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPSIP31758_RS06835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPSIP31758_RS06840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPSIP31758_RS06845	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPSIP31758_RS06850	COG2169	Transcriptional regulator
YPSIP31758_RS06850	COG1917	Cupin 2, conserved barrel domain protein
YPSIP31758_RS06870	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPSIP31758_RS06875	COG0033	Phosphoglucomutase
YPSIP31758_RS06895	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS06900	COG2205	protein histidine kinase activity
YPSIP31758_RS06935	COG3272	Protein of unknown function (DUF1722)
YPSIP31758_RS06945	COG5212	phosphodiesterase
YPSIP31758_RS06950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPSIP31758_RS06955	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YPSIP31758_RS06960	COG1984	allophanate hydrolase subunit 2
YPSIP31758_RS07010	COG0513	Belongs to the DEAD box helicase family
YPSIP31758_RS07020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPSIP31758_RS07035	COG3026	antisigma factor binding
YPSIP31758_RS07040	COG3086	response to oxidative stress
YPSIP31758_RS07085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPSIP31758_RS07090	COG1737	Transcriptional regulator
YPSIP31758_RS07100	COG0560	Phosphoserine phosphatase
YPSIP31758_RS07130	COG2205	protein histidine kinase activity
YPSIP31758_RS07135	COG3170	Tfp pilus assembly protein FimV
YPSIP31758_RS07140	COG2204	response regulator
YPSIP31758_RS07145	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPSIP31758_RS07145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPSIP31758_RS07150	COG0347	Belongs to the P(II) protein family
YPSIP31758_RS07155	COG2188	Transcriptional regulator
YPSIP31758_RS07160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPSIP31758_RS07160	COG1017	nitric oxide dioxygenase activity
YPSIP31758_RS07180	COG2814	Major facilitator Superfamily
YPSIP31758_RS07185	COG3711	transcriptional antiterminator
YPSIP31758_RS07190	COG3683	transport system, periplasmic component
YPSIP31758_RS07195	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPSIP31758_RS07215	COG1104	cysteine desulfurase activity
YPSIP31758_RS07220	COG0822	iron-sulfur transferase activity
YPSIP31758_RS07240	COG0633	Ferredoxin
YPSIP31758_RS07245	COG2975	iron-sulfur cluster assembly
YPSIP31758_RS07260	COG3468	outer membrane autotransporter barrel domain protein
YPSIP31758_RS07265	COG3468	outer membrane autotransporter barrel domain protein
YPSIP31758_RS07310	COG2976	Protein conserved in bacteria
YPSIP31758_RS07315	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPSIP31758_RS07330	COG1645	bacterial-type flagellum-dependent swarming motility
YPSIP31758_RS07340	COG0517	IMP dehydrogenase activity
YPSIP31758_RS07340	COG0516	GMP reductase activity
YPSIP31758_RS07395	COG0351	phosphomethylpyrimidine kinase
YPSIP31758_RS07415	COG0826	peptidase U32
YPSIP31758_RS07420	COG3422	double-strand break repair
YPSIP31758_RS07425	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS07430	COG2205	protein histidine kinase activity
YPSIP31758_RS07455	COG3842	ATPase activity
YPSIP31758_RS07465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPSIP31758_RS07475	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPSIP31758_RS07480	COG1177	transmembrane transport
YPSIP31758_RS07485	COG0443	Heat shock 70 kDa protein
YPSIP31758_RS07490	COG2239	Acts as a magnesium transporter
YPSIP31758_RS07505	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPSIP31758_RS07515	COG0581	inorganic phosphate transmembrane transporter activity
YPSIP31758_RS07530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPSIP31758_RS07535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPSIP31758_RS07550	COG2233	PERMEase
YPSIP31758_RS07560	COG1393	Belongs to the ArsC family
YPSIP31758_RS07565	COG4783	chaperone-mediated protein folding
YPSIP31758_RS07570	COG0628	permease
YPSIP31758_RS07590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPSIP31758_RS07595	COG2716	regulation of RNA biosynthetic process
YPSIP31758_RS07605	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPSIP31758_RS07615	COG2321	neutral zinc metallopeptidase
YPSIP31758_RS07635	COG1876	peptidase activity
YPSIP31758_RS07645	COG1393	Belongs to the ArsC family
YPSIP31758_RS07660	COG1175	transmembrane transport
YPSIP31758_RS07665	COG3842	ATPase activity
YPSIP31758_RS07670	COG3119	arylsulfatase activity
YPSIP31758_RS07675	COG0641	radical SAM
YPSIP31758_RS07680	COG1988	membrane-bound metal-dependent
YPSIP31758_RS07690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPSIP31758_RS07700	COG2197	response regulator
YPSIP31758_RS07705	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPSIP31758_RS07705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPSIP31758_RS07710	COG3062	negative regulation of establishment of protein localization
YPSIP31758_RS07720	COG3043	anaerobic respiration
YPSIP31758_RS07725	COG3005	denitrification pathway
YPSIP31758_RS07775	COG0456	acetyltransferase
YPSIP31758_RS07795	COG3111	PFAM Bacterial OB fold (BOF) protein
YPSIP31758_RS07805	COG2837	iron assimilation
YPSIP31758_RS07810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPSIP31758_RS07825	COG2731	YhcH YjgK YiaL family protein
YPSIP31758_RS07835	COG1737	Transcriptional regulator
YPSIP31758_RS07845	COG4150	thiosulfate binding
YPSIP31758_RS07850	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPSIP31758_RS07855	COG4208	sulfate ABC transporter
YPSIP31758_RS07870	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS07875	COG5002	protein histidine kinase activity
YPSIP31758_RS07875	COG3850	Histidine kinase
YPSIP31758_RS07885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPSIP31758_RS07900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPSIP31758_RS07915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPSIP31758_RS07920	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS07925	COG2205	protein histidine kinase activity
YPSIP31758_RS07940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPSIP31758_RS07950	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPSIP31758_RS07965	COG3530	Putative quorum-sensing-regulated virulence factor
YPSIP31758_RS08015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPSIP31758_RS08030	COG0667	Aldo Keto reductase
YPSIP31758_RS08055	COG0436	Aminotransferase
YPSIP31758_RS08060	COG3038	cytochrome b561
YPSIP31758_RS08090	COG3381	protein complex oligomerization
YPSIP31758_RS08095	COG3302	dmso reductase anchor subunit
YPSIP31758_RS08100	COG0437	4 iron, 4 sulfur cluster binding
YPSIP31758_RS08105	COG0243	molybdopterin cofactor binding
YPSIP31758_RS08145	COG2951	lytic endotransglycosylase activity
YPSIP31758_RS08205	COG3121	Chaperone
YPSIP31758_RS08210	COG3188	usher protein
YPSIP31758_RS08290	COG2824	Alkylphosphonate utilization operon protein PhnA
YPSIP31758_RS08300	COG1704	LemA family
YPSIP31758_RS08335	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPSIP31758_RS08340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPSIP31758_RS08345	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPSIP31758_RS08355	COG1138	Cytochrome C-type biogenesis protein
YPSIP31758_RS08360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPSIP31758_RS08365	COG3088	subunit of a heme lyase
YPSIP31758_RS08365	COG4235	cytochrome complex assembly
YPSIP31758_RS08370	COG3088	subunit of a heme lyase
YPSIP31758_RS08370	COG4235	cytochrome complex assembly
YPSIP31758_RS08385	COG3691	Protein conserved in bacteria
YPSIP31758_RS08400	COG2062	phosphohistidine phosphatase, SixA
YPSIP31758_RS08410	COG2890	protein-(glutamine-N5) methyltransferase activity
YPSIP31758_RS08425	COG0730	response to heat
YPSIP31758_RS08430	COG3101	peptidyl-lysine hydroxylation
YPSIP31758_RS08445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPSIP31758_RS08450	COG1794	racemase activity, acting on amino acids and derivatives
YPSIP31758_RS08465	COG0697	spore germination
YPSIP31758_RS08485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPSIP31758_RS08495	COG0586	Pfam SNARE associated Golgi protein
YPSIP31758_RS08505	COG0285	dihydrofolate synthase activity
YPSIP31758_RS08510	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPSIP31758_RS08515	COG1286	toxin biosynthetic process
YPSIP31758_RS08520	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPSIP31758_RS08530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPSIP31758_RS08535	COG4215	(ABC) transporter
YPSIP31758_RS08540	COG4160	amino acid transport
YPSIP31758_RS08545	COG4598	ABC transporter
YPSIP31758_RS08550	COG1090	epimerase
YPSIP31758_RS08560	COG0622	Phosphoesterase
YPSIP31758_RS08565	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPSIP31758_RS08570	COG3037	sugar-specific permease SgaT UlaA
YPSIP31758_RS08585	COG1609	Transcriptional regulator
YPSIP31758_RS08590	COG0857	belongs to the CobB CobQ family
YPSIP31758_RS08590	COG0280	phosphate acetyltransferase
YPSIP31758_RS08615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPSIP31758_RS08620	COG0471	metal ion transport
YPSIP31758_RS08620	COG0490	domain, Protein
YPSIP31758_RS08635	COG0436	Aminotransferase
YPSIP31758_RS08645	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS08675	COG1034	ATP synthesis coupled electron transport
YPSIP31758_RS08690	COG0839	Belongs to the complex I subunit 6 family
YPSIP31758_RS08700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPSIP31758_RS08705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPSIP31758_RS08720	COG2731	YhcH YjgK YiaL family protein
YPSIP31758_RS08725	COG3265	gluconokinase activity
YPSIP31758_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS08735	COG1649	PFAM Uncharacterised BCR, COG1649
YPSIP31758_RS08740	COG1609	Transcriptional regulator
YPSIP31758_RS08750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPSIP31758_RS08755	COG0129	dihydroxy-acid dehydratase activity
YPSIP31758_RS08770	COG4575	ribosome binding
YPSIP31758_RS08780	COG1169	isochorismate synthase
YPSIP31758_RS08795	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPSIP31758_RS08810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPSIP31758_RS08830	COG1126	abc transporter atp-binding protein
YPSIP31758_RS08835	COG0765	amino acid transport
YPSIP31758_RS08840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPSIP31758_RS08870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPSIP31758_RS08890	COG1063	alcohol dehydrogenase
YPSIP31758_RS08895	COG1879	ABC-type sugar transport system periplasmic component
YPSIP31758_RS08900	COG1129	ABC transporter
YPSIP31758_RS08905	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS08910	COG1609	Transcriptional regulator
YPSIP31758_RS08915	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS08920	COG0473	3-isopropylmalate dehydrogenase activity
YPSIP31758_RS08930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPSIP31758_RS08935	COG4638	Rieske (2fe-2S)
YPSIP31758_RS08940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPSIP31758_RS08945	COG2831	hemolysin activation secretion protein
YPSIP31758_RS08960	COG3210	domain, Protein
YPSIP31758_RS08970	COG3842	ATPase activity
YPSIP31758_RS08980	COG1609	Transcriptional regulator
YPSIP31758_RS08995	COG0395	ABC-type sugar transport system, permease component
YPSIP31758_RS09000	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPSIP31758_RS09020	COG0668	transmembrane transport
YPSIP31758_RS09025	COG1518	maintenance of DNA repeat elements
YPSIP31758_RS09030	COG1203	CRISPR-associated helicase, Cas3
YPSIP31758_RS09055	COG0667	Aldo Keto reductase
YPSIP31758_RS09065	COG0477	Major facilitator Superfamily
YPSIP31758_RS09075	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS09080	COG2771	luxR family
YPSIP31758_RS09085	COG3916	Acyl-homoserine-lactone synthase
YPSIP31758_RS09110	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YPSIP31758_RS09115	COG2943	transferase activity, transferring hexosyl groups
YPSIP31758_RS09120	COG5645	(Lipo)protein
YPSIP31758_RS09130	COG1560	Kdo2-lipid A biosynthetic process
YPSIP31758_RS09155	COG0628	permease
YPSIP31758_RS09190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPSIP31758_RS09195	COG1530	ribonuclease E activity
YPSIP31758_RS09200	COG0564	pseudouridine synthase activity
YPSIP31758_RS09205	COG0424	maF-like protein
YPSIP31758_RS09210	COG1399	metal-binding, possibly nucleic acid-binding protein
YPSIP31758_RS09215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPSIP31758_RS09245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPSIP31758_RS09250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPSIP31758_RS09255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPSIP31758_RS09265	COG0470	DNA polymerase III
YPSIP31758_RS09270	COG0084	hydrolase, TatD family'
YPSIP31758_RS09275	COG1263	PTS System
YPSIP31758_RS09275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPSIP31758_RS09280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPSIP31758_RS09285	COG0537	adenosine 5'-monophosphoramidase activity
YPSIP31758_RS09290	COG5633	Lipoprotein
YPSIP31758_RS09315	COG1252	NADH dehydrogenase
YPSIP31758_RS09330	COG3134	Outer membrane lipoprotein
YPSIP31758_RS09335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPSIP31758_RS09340	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPSIP31758_RS09350	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPSIP31758_RS09370	COG2850	peptidyl-arginine hydroxylation
YPSIP31758_RS09380	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS09390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPSIP31758_RS09410	COG1187	pseudouridine synthase activity
YPSIP31758_RS09415	COG0538	isocitrate dehydrogenase activity
YPSIP31758_RS09430	COG0840	transmembrane signaling receptor activity
YPSIP31758_RS09435	COG0702	epimerase
YPSIP31758_RS09440	COG1733	regulation of RNA biosynthetic process
YPSIP31758_RS09465	COG1522	sequence-specific DNA binding
YPSIP31758_RS09475	COG0604	alcohol dehydrogenase
YPSIP31758_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS09475	COG3321	synthase
YPSIP31758_RS09495	COG0840	transmembrane signaling receptor activity
YPSIP31758_RS09505	COG1285	pathogenesis
YPSIP31758_RS09530	COG1360	Flagellar Motor Protein
YPSIP31758_RS09535	COG2198	Histidine kinase
YPSIP31758_RS09535	COG0643	Histidine kinase
YPSIP31758_RS09540	COG0835	chemotaxis
YPSIP31758_RS09555	COG0840	transmembrane signaling receptor activity
YPSIP31758_RS09560	COG0840	transmembrane signaling receptor activity
YPSIP31758_RS09565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPSIP31758_RS09575	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS09580	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPSIP31758_RS09590	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPSIP31758_RS09595	COG5295	Hep Hag repeat protein
YPSIP31758_RS09595	COG5295	Hep Hag repeat protein
YPSIP31758_RS09595	COG5295	Hep Hag repeat protein
YPSIP31758_RS09605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPSIP31758_RS09670	COG3008	intermembrane lipid transfer
YPSIP31758_RS09675	COG2995	paraquat-inducible protein a
YPSIP31758_RS09680	COG1956	GAF domain-containing protein
YPSIP31758_RS09690	COG0793	Belongs to the peptidase S41A family
YPSIP31758_RS09705	COG3539	Fimbrial protein
YPSIP31758_RS09710	COG3121	Chaperone
YPSIP31758_RS09725	COG3121	Chaperone
YPSIP31758_RS09730	COG2814	Major facilitator Superfamily
YPSIP31758_RS09735	COG0823	Involved in the tonB-independent uptake of proteins
YPSIP31758_RS09745	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPSIP31758_RS09750	COG1823	symporter activity
YPSIP31758_RS09755	COG1988	membrane-bound metal-dependent
YPSIP31758_RS09760	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPSIP31758_RS09765	COG1653	transport
YPSIP31758_RS09770	COG3842	ATPase activity
YPSIP31758_RS09775	COG0395	ABC-type sugar transport system, permease component
YPSIP31758_RS09780	COG1175	transmembrane transport
YPSIP31758_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS09800	COG1917	Cupin 2, conserved barrel domain protein
YPSIP31758_RS09805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPSIP31758_RS09815	COG3001	Fructosamine kinase
YPSIP31758_RS09825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPSIP31758_RS09830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPSIP31758_RS09835	COG1121	(ABC) transporter
YPSIP31758_RS09840	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPSIP31758_RS09865	COG4249	Peptidase C14 caspase catalytic subunit p20
YPSIP31758_RS09900	COG0776	regulation of translation
YPSIP31758_RS09915	COG0386	Belongs to the glutathione peroxidase family
YPSIP31758_RS09965	COG0791	NLP P60 protein
YPSIP31758_RS09990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPSIP31758_RS09990	COG0574	Belongs to the PEP-utilizing enzyme family
YPSIP31758_RS09995	COG0628	permease
YPSIP31758_RS10000	COG0277	FAD linked oxidase domain protein
YPSIP31758_RS10000	COG0247	lactate metabolic process
YPSIP31758_RS10005	COG2050	protein possibly involved in aromatic compounds catabolism
YPSIP31758_RS10015	COG0316	Belongs to the HesB IscA family
YPSIP31758_RS10020	COG0719	Fe-S assembly protein
YPSIP31758_RS10025	COG0396	ATPase activity
YPSIP31758_RS10030	COG0719	Fe-S assembly protein
YPSIP31758_RS10045	COG1376	ErfK ybiS ycfS ynhG family protein
YPSIP31758_RS10045	COG1388	LysM domain
YPSIP31758_RS10080	COG0307	riboflavin synthase, alpha
YPSIP31758_RS10085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPSIP31758_RS10090	COG2814	Major facilitator Superfamily
YPSIP31758_RS10095	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS10110	COG0791	NLP P60 protein
YPSIP31758_RS10120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPSIP31758_RS10135	COG0346	lactoylglutathione lyase activity
YPSIP31758_RS10145	COG1902	pentaerythritol trinitrate reductase activity
YPSIP31758_RS10150	COG1309	transcriptional regulator
YPSIP31758_RS10155	COG2194	sulfuric ester hydrolase activity
YPSIP31758_RS10160	COG3313	Fe-S protein
YPSIP31758_RS10165	COG4989	oxidoreductase activity
YPSIP31758_RS10180	COG3133	Outer membrane lipoprotein
YPSIP31758_RS10190	COG3895	Periplasmic Protein
YPSIP31758_RS10210	COG0625	glutathione transferase activity
YPSIP31758_RS10225	COG3104	oligopeptide transport
YPSIP31758_RS10230	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPSIP31758_RS10230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPSIP31758_RS10235	COG4172	Belongs to the ABC transporter superfamily
YPSIP31758_RS10245	COG4171	peptide transport system, permease
YPSIP31758_RS10250	COG4168	peptide transport system, permease
YPSIP31758_RS10255	COG4166	transmembrane transport
YPSIP31758_RS10265	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPSIP31758_RS10270	COG1842	Phage shock protein A
YPSIP31758_RS10280	COG1983	PspC domain protein
YPSIP31758_RS10290	COG3106	COG3106 Predicted ATPase
YPSIP31758_RS10300	COG5654	RES domain protein
YPSIP31758_RS10305	COG5642	Protein of unknown function (DUF2384)
YPSIP31758_RS10315	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPSIP31758_RS10320	COG4948	Mandelate Racemase Muconate Lactonizing
YPSIP31758_RS10325	COG2866	Carboxypeptidase
YPSIP31758_RS10330	COG4166	transmembrane transport
YPSIP31758_RS10350	COG0657	acetylesterase activity
YPSIP31758_RS10360	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPSIP31758_RS10360	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPSIP31758_RS10360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPSIP31758_RS10360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPSIP31758_RS10370	COG1285	pathogenesis
YPSIP31758_RS10375	COG3042	response to heat
YPSIP31758_RS10380	COG3187	Heat shock protein
YPSIP31758_RS10385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPSIP31758_RS10390	COG2911	Protein conserved in bacteria
YPSIP31758_RS10400	COG3784	Protein of unknown function (DUF1318)
YPSIP31758_RS10405	COG0246	Mannitol dehydrogenase
YPSIP31758_RS10410	COG2390	Transcriptional regulator
YPSIP31758_RS10420	COG1643	Atp-dependent helicase
YPSIP31758_RS10435	COG3591	Belongs to the peptidase S1B family
YPSIP31758_RS10450	COG3038	cytochrome b561
YPSIP31758_RS10470	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPSIP31758_RS10475	COG2205	protein histidine kinase activity
YPSIP31758_RS10480	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS10490	COG0531	amino acid
YPSIP31758_RS10505	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPSIP31758_RS10510	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPSIP31758_RS10515	COG0589	response to stress
YPSIP31758_RS10520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPSIP31758_RS10525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPSIP31758_RS10545	COG1011	Hydrolase
YPSIP31758_RS10550	COG0440	acetolactate synthase activity
YPSIP31758_RS10555	COG0028	Belongs to the TPP enzyme family
YPSIP31758_RS10580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPSIP31758_RS10590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPSIP31758_RS10605	COG1129	ABC transporter
YPSIP31758_RS10610	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS10615	COG1879	ABC-type sugar transport system periplasmic component
YPSIP31758_RS10625	COG1609	Transcriptional regulator
YPSIP31758_RS10630	COG1757	Na H antiporter
YPSIP31758_RS10635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPSIP31758_RS10665	COG3284	Transcriptional regulator
YPSIP31758_RS10670	COG4221	oxidoreductase activity
YPSIP31758_RS10690	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPSIP31758_RS10695	COG1940	carbohydrate kinase activity
YPSIP31758_RS10700	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS10705	COG2814	Major facilitator Superfamily
YPSIP31758_RS10715	COG0114	fumarate hydratase activity
YPSIP31758_RS10725	COG5339	Protein conserved in bacteria
YPSIP31758_RS10745	COG0385	Bile acid
YPSIP31758_RS10750	COG0673	inositol 2-dehydrogenase activity
YPSIP31758_RS10760	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS10765	COG1129	ABC transporter
YPSIP31758_RS10770	COG1879	ABC-type sugar transport system periplasmic component
YPSIP31758_RS10785	COG2274	protein secretion by the type I secretion system
YPSIP31758_RS10820	COG2207	Transcriptional regulator
YPSIP31758_RS10820	COG3708	Transcriptional regulator
YPSIP31758_RS10830	COG4659	FMN binding
YPSIP31758_RS10840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPSIP31758_RS10845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPSIP31758_RS10850	COG2271	Major facilitator Superfamily
YPSIP31758_RS10860	COG1966	Carbon starvation protein
YPSIP31758_RS10865	COG2879	small protein
YPSIP31758_RS10870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPSIP31758_RS10890	COG0023	Translation Initiation Factor
YPSIP31758_RS10905	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPSIP31758_RS10910	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPSIP31758_RS10915	COG0671	phosphoesterase, PA-phosphatase related
YPSIP31758_RS10925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPSIP31758_RS10935	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS10955	COG0616	signal peptide processing
YPSIP31758_RS10960	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS10970	COG1187	pseudouridine synthase activity
YPSIP31758_RS10975	COG0009	L-threonylcarbamoyladenylate synthase
YPSIP31758_RS11000	COG0512	Glutamine amidotransferase of anthranilate synthase
YPSIP31758_RS11010	COG0134	indole-3-glycerol-phosphate synthase activity
YPSIP31758_RS11010	COG0135	phosphoribosylanthranilate isomerase activity
YPSIP31758_RS11030	COG3047	cAMP biosynthetic process
YPSIP31758_RS11060	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPSIP31758_RS11065	COG2350	Protein conserved in bacteria
YPSIP31758_RS11095	COG4608	Belongs to the ABC transporter superfamily
YPSIP31758_RS11100	COG0444	Belongs to the ABC transporter superfamily
YPSIP31758_RS11105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPSIP31758_RS11110	COG0601	transmembrane transport
YPSIP31758_RS11120	COG2095	MarC family integral membrane protein
YPSIP31758_RS11125	COG1012	belongs to the aldehyde dehydrogenase family
YPSIP31758_RS11125	COG1454	alcohol dehydrogenase
YPSIP31758_RS11155	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS11165	COG0788	formyltetrahydrofolate deformylase activity
YPSIP31758_RS11180	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS11185	COG0708	Exodeoxyribonuclease III
YPSIP31758_RS11190	COG0494	nUDIX hydrolase
YPSIP31758_RS11200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPSIP31758_RS11210	COG0778	Nitroreductase
YPSIP31758_RS11215	COG0616	signal peptide processing
YPSIP31758_RS11220	COG0252	asparaginase activity
YPSIP31758_RS11225	COG1335	isochorismatase
YPSIP31758_RS11230	COG3139	Protein of unknown function (DUF1315)
YPSIP31758_RS11250	COG3713	MltA-interacting MipA family protein
YPSIP31758_RS11255	COG2766	serine protein kinase
YPSIP31758_RS11270	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS11280	COG2814	Major facilitator Superfamily
YPSIP31758_RS11290	COG2719	SpoVR family
YPSIP31758_RS11320	COG1104	cysteine desulfurase activity
YPSIP31758_RS11335	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPSIP31758_RS11340	COG2951	lytic endotransglycosylase activity
YPSIP31758_RS11355	COG2894	cell division
YPSIP31758_RS11360	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPSIP31758_RS11365	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPSIP31758_RS11370	COG0318	PFAM AMP-dependent synthetase and ligase
YPSIP31758_RS11375	COG3065	identical protein binding
YPSIP31758_RS11385	COG1199	ATP-dependent helicase activity
YPSIP31758_RS11390	COG0251	oxidation-reduction process
YPSIP31758_RS11405	COG0800	Aldolase
YPSIP31758_RS11415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPSIP31758_RS11420	COG1737	Transcriptional regulator
YPSIP31758_RS11425	COG0469	pyruvate kinase activity
YPSIP31758_RS11430	COG1560	Kdo2-lipid A biosynthetic process
YPSIP31758_RS11435	COG0739	heme binding
YPSIP31758_RS11440	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPSIP31758_RS11450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPSIP31758_RS11475	COG0494	nUDIX hydrolase
YPSIP31758_RS11485	COG1801	Protein of unknown function DUF72
YPSIP31758_RS11490	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPSIP31758_RS11510	COG3102	Protein conserved in bacteria
YPSIP31758_RS11530	COG0728	peptidoglycan biosynthetic process
YPSIP31758_RS11535	COG0673	inositol 2-dehydrogenase activity
YPSIP31758_RS11545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPSIP31758_RS11560	COG3381	protein complex oligomerization
YPSIP31758_RS11575	COG1940	carbohydrate kinase activity
YPSIP31758_RS11580	COG0584	glycerophosphoryl diester phosphodiesterase
YPSIP31758_RS11590	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPSIP31758_RS11595	COG3833	ABC-type maltose transport systems, permease component
YPSIP31758_RS11620	COG0659	secondary active sulfate transmembrane transporter activity
YPSIP31758_RS11640	COG2890	protein-(glutamine-N5) methyltransferase activity
YPSIP31758_RS11670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPSIP31758_RS11690	COG0012	GTP binding
YPSIP31758_RS11735	COG5002	protein histidine kinase activity
YPSIP31758_RS11775	COG0500	methyltransferase
YPSIP31758_RS11840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPSIP31758_RS11845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPSIP31758_RS11860	COG0402	S-adenosylhomocysteine deaminase activity
YPSIP31758_RS11915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPSIP31758_RS11920	COG3850	Histidine kinase
YPSIP31758_RS11925	COG0387	Pfam Sodium calcium exchanger
YPSIP31758_RS11930	COG1702	phosphate starvation-inducible protein PhoH
YPSIP31758_RS11945	COG3658	cytochrome
YPSIP31758_RS11950	COG1215	transferase activity, transferring glycosyl groups
YPSIP31758_RS11955	COG0726	polysaccharide deacetylase
YPSIP31758_RS11955	COG1649	PFAM Uncharacterised BCR, COG1649
YPSIP31758_RS11960	COG0457	Tetratricopeptide repeat
YPSIP31758_RS11965	COG0006	proline dipeptidase activity
YPSIP31758_RS11985	COG1136	(ABC) transporter
YPSIP31758_RS11985	COG0577	efflux transmembrane transporter activity
YPSIP31758_RS11995	COG0577	efflux transmembrane transporter activity
YPSIP31758_RS11995	COG1136	(ABC) transporter
YPSIP31758_RS12010	COG0672	)-iron permease
YPSIP31758_RS12020	COG2066	Belongs to the glutaminase family
YPSIP31758_RS12025	COG1349	DNA-binding transcription factor activity
YPSIP31758_RS12035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPSIP31758_RS12040	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPSIP31758_RS12055	COG2814	Major facilitator Superfamily
YPSIP31758_RS12080	COG2030	dehydratase
YPSIP31758_RS12085	COG0427	acetyl-CoA hydrolase
YPSIP31758_RS12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPSIP31758_RS12095	COG2205	protein histidine kinase activity
YPSIP31758_RS12110	COG3188	usher protein
YPSIP31758_RS12120	COG3121	Chaperone
YPSIP31758_RS12135	COG3842	ATPase activity
YPSIP31758_RS12140	COG0395	ABC-type sugar transport system, permease component
YPSIP31758_RS12155	COG0673	inositol 2-dehydrogenase activity
YPSIP31758_RS12165	COG2188	Transcriptional regulator
YPSIP31758_RS12285	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
YPSIP31758_RS12410	COG3566	protein conserved in bacteria
YPSIP31758_RS12420	COG3567	Phage-associated protein, HI1409 family
YPSIP31758_RS12430	COG3077	Addiction module antitoxin, RelB DinJ family
YPSIP31758_RS12435	COG2026	Addiction module toxin, RelE StbE family
YPSIP31758_RS12455	COG1475	DNA binding
YPSIP31758_RS12475	COG3772	lysozyme
YPSIP31758_RS12600	COG2197	response regulator
YPSIP31758_RS12610	COG3136	membrane protein required for alginate biosynthesis
YPSIP31758_RS12630	COG1113	amino acid transport
YPSIP31758_RS12650	COG2822	iron ion transport
YPSIP31758_RS12655	COG0672	)-iron permease
YPSIP31758_RS12670	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPSIP31758_RS12670	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPSIP31758_RS12670	COG0506	proline dehydrogenase activity
YPSIP31758_RS12685	COG1126	abc transporter atp-binding protein
YPSIP31758_RS12690	COG0765	amino acid transport
YPSIP31758_RS12695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPSIP31758_RS12710	COG1191	sigma factor activity
YPSIP31758_RS12745	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPSIP31758_RS12750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPSIP31758_RS12765	COG1677	Flagellar hook-basal body complex protein FliE
YPSIP31758_RS12785	COG1157	protein secretion by the type III secretion system
YPSIP31758_RS12800	COG1580	Controls the rotational direction of flagella during chemotaxis
YPSIP31758_RS12825	COG1987	bacterial-type flagellum assembly
YPSIP31758_RS12845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPSIP31758_RS12850	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS12855	COG1129	ABC transporter
YPSIP31758_RS12865	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS12870	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS12870	COG3347	Dehydrogenase
YPSIP31758_RS12875	COG2390	Transcriptional regulator
YPSIP31758_RS12885	COG1256	bacterial-type flagellum assembly
YPSIP31758_RS12925	COG1558	bacterial-type flagellum-dependent cell motility
YPSIP31758_RS12930	COG1815	bacterial-type flagellum-dependent cell motility
YPSIP31758_RS12940	COG2747	anti-sigma28 factor FlgM
YPSIP31758_RS12945	COG3418	PFAM FlgN family protein
YPSIP31758_RS12965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPSIP31758_RS12970	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPSIP31758_RS13000	COG2372	response to copper ion
YPSIP31758_RS13005	COG1528	Iron-storage protein
YPSIP31758_RS13020	COG1770	oligopeptidase
YPSIP31758_RS13035	COG3141	response to X-ray
YPSIP31758_RS13040	COG0513	Belongs to the DEAD box helicase family
YPSIP31758_RS13065	COG1760	l-serine dehydratase
YPSIP31758_RS13070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPSIP31758_RS13075	COG2368	4-hydroxyphenylacetate
YPSIP31758_RS13090	COG3971	2-oxopent-4-enoate hydratase activity
YPSIP31758_RS13100	COG3384	dioxygenase
YPSIP31758_RS13105	COG1012	belongs to the aldehyde dehydrogenase family
YPSIP31758_RS13120	COG1846	Transcriptional regulator
YPSIP31758_RS13125	COG1253	flavin adenine dinucleotide binding
YPSIP31758_RS13130	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPSIP31758_RS13130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPSIP31758_RS13135	COG3715	PTS system
YPSIP31758_RS13140	COG3716	PTS system mannose fructose sorbose family IID component
YPSIP31758_RS13160	COG3447	MASE1 domain protein
YPSIP31758_RS13160	COG5002	protein histidine kinase activity
YPSIP31758_RS13160	COG5001	Diguanylate cyclase
YPSIP31758_RS13170	COG2226	methyltransferase
YPSIP31758_RS13175	COG1496	oxidoreductase activity
YPSIP31758_RS13200	COG1113	amino acid transport
YPSIP31758_RS13235	COG2207	Transcriptional regulator
YPSIP31758_RS13245	COG1132	(ABC) transporter
YPSIP31758_RS13280	COG2223	nitrite transmembrane transporter activity
YPSIP31758_RS13300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPSIP31758_RS13325	COG3122	Protein conserved in bacteria
YPSIP31758_RS13345	COG0534	Mate efflux family protein
YPSIP31758_RS13360	COG4948	Mandelate Racemase Muconate Lactonizing
YPSIP31758_RS13370	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS13375	COG3011	Protein conserved in bacteria
YPSIP31758_RS13380	COG2271	Major facilitator Superfamily
YPSIP31758_RS13385	COG1470	cell adhesion involved in biofilm formation
YPSIP31758_RS13385	COG1388	LysM domain
YPSIP31758_RS13400	COG2925	Exonuclease
YPSIP31758_RS13405	COG0531	amino acid
YPSIP31758_RS13415	COG0371	Dehydrogenase
YPSIP31758_RS13420	COG1129	ABC transporter
YPSIP31758_RS13425	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS13440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPSIP31758_RS13450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPSIP31758_RS13480	COG0140	phosphoribosyl-ATP diphosphatase activity
YPSIP31758_RS13480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPSIP31758_RS13490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPSIP31758_RS13495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPSIP31758_RS13510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPSIP31758_RS13515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPSIP31758_RS13520	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPSIP31758_RS13525	COG1120	ATPase activity
YPSIP31758_RS13540	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPSIP31758_RS13545	COG0076	glutamate decarboxylase activity
YPSIP31758_RS13550	COG4114	ferric iron reductase
YPSIP31758_RS13555	COG1253	flavin adenine dinucleotide binding
YPSIP31758_RS13560	COG2982	Protein involved in outer membrane biogenesis
YPSIP31758_RS13575	COG0489	protein tyrosine kinase activity
YPSIP31758_RS13600	COG2814	Major facilitator Superfamily
YPSIP31758_RS13610	COG1346	cytolysis
YPSIP31758_RS13625	COG2949	membrane
YPSIP31758_RS13630	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS13645	COG2311	Membrane
YPSIP31758_RS13655	COG0477	Major facilitator Superfamily
YPSIP31758_RS13660	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS13690	COG1136	(ABC) transporter
YPSIP31758_RS13700	COG0303	'Molybdopterin
YPSIP31758_RS13715	COG0488	(ABC) transporter
YPSIP31758_RS13860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPSIP31758_RS13865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPSIP31758_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS13880	COG1024	Enoyl-CoA hydratase
YPSIP31758_RS13890	COG3425	synthase
YPSIP31758_RS13895	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS13900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPSIP31758_RS13905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPSIP31758_RS13915	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS13950	COG2920	part of a sulfur-relay system
YPSIP31758_RS13970	COG1832	CoA-binding protein
YPSIP31758_RS13985	COG0210	DNA helicase
YPSIP31758_RS13990	COG3304	Inner membrane component domain
YPSIP31758_RS13995	COG1289	transmembrane transporter activity
YPSIP31758_RS14000	COG3070	regulator of competence-specific genes
YPSIP31758_RS14035	COG1067	ATP-dependent peptidase activity
YPSIP31758_RS14050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPSIP31758_RS14055	COG3130	regulation of translation
YPSIP31758_RS14065	COG3009	Protein conserved in bacteria
YPSIP31758_RS14070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPSIP31758_RS14070	COG3008	intermembrane lipid transfer
YPSIP31758_RS14075	COG2995	paraquat-inducible protein a
YPSIP31758_RS14080	COG0488	(ABC) transporter
YPSIP31758_RS14090	COG3217	Mosc domain protein beta barrel domain protein
YPSIP31758_RS14090	COG0633	Ferredoxin
YPSIP31758_RS14105	COG0308	aminopeptidase N
YPSIP31758_RS14125	COG1448	Aminotransferase
YPSIP31758_RS14130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPSIP31758_RS14135	COG3108	Peptidase M15
YPSIP31758_RS14140	COG2989	Protein conserved in bacteria
YPSIP31758_RS14160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPSIP31758_RS14170	COG3173	Aminoglycoside phosphotransferase
YPSIP31758_RS14185	COG1278	Cold shock
YPSIP31758_RS14195	COG5383	Protein conserved in bacteria
YPSIP31758_RS14210	COG0658	competence protein
YPSIP31758_RS14210	COG2333	competence protein COMEC
YPSIP31758_RS14225	COG0539	negative regulation of cytoplasmic translation
YPSIP31758_RS14255	COG0252	asparaginase activity
YPSIP31758_RS14260	COG1944	ATP diphosphatase activity
YPSIP31758_RS14265	COG2116	formate transmembrane transporter activity
YPSIP31758_RS14270	COG1882	Formate acetyltransferase
YPSIP31758_RS14280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPSIP31758_RS14295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPSIP31758_RS14305	COG1674	ftsk spoiiie
YPSIP31758_RS14305	COG3107	peptidoglycan biosynthetic process
YPSIP31758_RS14315	COG0492	ferredoxin-NADP+ reductase activity
YPSIP31758_RS14330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPSIP31758_RS14340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPSIP31758_RS14345	COG0542	response to heat
YPSIP31758_RS14355	COG1278	Cold shock
YPSIP31758_RS14365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPSIP31758_RS14370	COG2990	Protein conserved in bacteria
YPSIP31758_RS14375	COG3593	DNA synthesis involved in DNA repair
YPSIP31758_RS14380	COG2431	L-lysine efflux transmembrane transporter activity
YPSIP31758_RS14390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPSIP31758_RS14395	COG0028	Belongs to the TPP enzyme family
YPSIP31758_RS14400	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPSIP31758_RS14405	COG0702	epimerase
YPSIP31758_RS14410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPSIP31758_RS14420	COG1605	Chorismate mutase
YPSIP31758_RS14425	COG1126	abc transporter atp-binding protein
YPSIP31758_RS14430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPSIP31758_RS14435	COG4215	(ABC) transporter
YPSIP31758_RS14440	COG4160	amino acid transport
YPSIP31758_RS14465	COG1120	ATPase activity
YPSIP31758_RS14470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPSIP31758_RS14490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPSIP31758_RS14505	COG1177	transmembrane transport
YPSIP31758_RS14510	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPSIP31758_RS14515	COG3842	ATPase activity
YPSIP31758_RS14520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPSIP31758_RS14555	COG0671	phosphoesterase, PA-phosphatase related
YPSIP31758_RS14565	COG1349	DNA-binding transcription factor activity
YPSIP31758_RS14570	COG0814	amino acid
YPSIP31758_RS14580	COG1686	Belongs to the peptidase S11 family
YPSIP31758_RS14585	COG2011	ABC-type metal ion transport system permease component
YPSIP31758_RS14610	COG0625	glutathione transferase activity
YPSIP31758_RS14615	COG4771	TonB-dependent receptor
YPSIP31758_RS14625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPSIP31758_RS14635	COG0833	amino acid
YPSIP31758_RS14640	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS14645	COG2855	membrane
YPSIP31758_RS14655	COG3188	usher protein
YPSIP31758_RS14660	COG3121	Chaperone
YPSIP31758_RS14675	COG3710	Transcriptional regulator
YPSIP31758_RS14680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPSIP31758_RS14680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPSIP31758_RS14680	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPSIP31758_RS14685	COG1105	Belongs to the carbohydrate kinase PfkB family
YPSIP31758_RS14705	COG1129	ABC transporter
YPSIP31758_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS14765	COG0246	Mannitol dehydrogenase
YPSIP31758_RS14770	COG2186	Transcriptional regulator
YPSIP31758_RS14780	COG0523	cobalamin synthesis protein
YPSIP31758_RS14785	COG0671	phosphoesterase, PA-phosphatase related
YPSIP31758_RS14790	COG0791	NLP P60 protein
YPSIP31758_RS14795	COG2200	EAL domain
YPSIP31758_RS14800	COG4166	transmembrane transport
YPSIP31758_RS14805	COG4174	ABC transporter (Permease)
YPSIP31758_RS14810	COG4239	(ABC) transporter, permease
YPSIP31758_RS14815	COG4172	Belongs to the ABC transporter superfamily
YPSIP31758_RS14825	COG2814	Major facilitator Superfamily
YPSIP31758_RS14830	COG1187	pseudouridine synthase activity
YPSIP31758_RS14835	COG1061	Type III restriction enzyme res subunit
YPSIP31758_RS14850	COG3082	Protein of unknown function (DUF1414)
YPSIP31758_RS14855	COG3083	sulfuric ester hydrolase activity
YPSIP31758_RS14870	COG3157	Type VI secretion system effector, Hcp
YPSIP31758_RS14890	COG2723	6-phospho-beta-galactosidase activity
YPSIP31758_RS14895	COG1737	Transcriptional regulator
YPSIP31758_RS14915	COG3299	homolog of phage Mu protein gp47
YPSIP31758_RS14955	COG4386	tail sheath protein
YPSIP31758_RS14975	COG3622	Belongs to the hyi family
YPSIP31758_RS14980	COG1349	DNA-binding transcription factor activity
YPSIP31758_RS14985	COG0235	Class ii aldolase
YPSIP31758_RS14990	COG3395	kinase activity
YPSIP31758_RS15035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPSIP31758_RS15065	COG2223	nitrite transmembrane transporter activity
YPSIP31758_RS15070	COG2198	Histidine kinase
YPSIP31758_RS15070	COG0642	Histidine kinase
YPSIP31758_RS15080	COG0784	Response regulator, receiver
YPSIP31758_RS15080	COG2205	protein histidine kinase activity
YPSIP31758_RS15110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPSIP31758_RS15125	COG0814	amino acid
YPSIP31758_RS15155	COG0697	spore germination
YPSIP31758_RS15165	COG1982	Orn Lys Arg decarboxylase major
YPSIP31758_RS15170	COG0531	amino acid
YPSIP31758_RS15175	COG1174	glycine betaine transport
YPSIP31758_RS15180	COG1125	glycine betaine transport
YPSIP31758_RS15185	COG1174	glycine betaine transport
YPSIP31758_RS15190	COG1732	Glycine betaine
YPSIP31758_RS15195	COG2897	thiosulfate sulfurtransferase activity
YPSIP31758_RS15215	COG1122	ATPase activity
YPSIP31758_RS15235	COG4807	Protein conserved in bacteria
YPSIP31758_RS15250	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPSIP31758_RS15260	COG2261	transglycosylase associated protein
YPSIP31758_RS15280	COG0277	FAD linked oxidase domain protein
YPSIP31758_RS15285	COG1686	Belongs to the peptidase S11 family
YPSIP31758_RS15295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPSIP31758_RS15310	COG0513	Belongs to the DEAD box helicase family
YPSIP31758_RS15315	COG1309	transcriptional regulator
YPSIP31758_RS15325	COG1131	(ABC) transporter
YPSIP31758_RS15330	COG0842	Transport permease protein
YPSIP31758_RS15335	COG0842	Transport permease protein
YPSIP31758_RS15355	COG1902	pentaerythritol trinitrate reductase activity
YPSIP31758_RS15375	COG2211	Major facilitator Superfamily
YPSIP31758_RS15380	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPSIP31758_RS15390	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS15395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPSIP31758_RS15415	COG0670	Belongs to the BI1 family
YPSIP31758_RS15420	COG0314	molybdopterin synthase activity
YPSIP31758_RS15425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPSIP31758_RS15435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPSIP31758_RS15445	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPSIP31758_RS15450	COG4628	conserved protein (DUF2132)
YPSIP31758_RS15460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YPSIP31758_RS15470	COG2226	methyltransferase
YPSIP31758_RS15495	COG0561	phosphatase activity
YPSIP31758_RS15505	COG4149	molybdate abc transporter
YPSIP31758_RS15510	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPSIP31758_RS15520	COG2005	Transcriptional regulator
YPSIP31758_RS15520	COG3585	molybdate ion transport
YPSIP31758_RS15525	COG1119	ATPase activity
YPSIP31758_RS15540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPSIP31758_RS15545	COG1085	galactose-1-phosphate uridylyltransferase
YPSIP31758_RS15555	COG2017	converts alpha-aldose to the beta-anomer
YPSIP31758_RS15570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPSIP31758_RS15575	COG1230	cation diffusion facilitator family transporter
YPSIP31758_RS15625	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPSIP31758_RS15630	COG2885	chlorophyll binding
YPSIP31758_RS15640	COG3064	Membrane
YPSIP31758_RS15640	COG3064	Membrane
YPSIP31758_RS15645	COG0848	biopolymer transport protein
YPSIP31758_RS15650	COG0811	peptide transport
YPSIP31758_RS15655	COG0824	Thioesterase
YPSIP31758_RS15660	COG3790	cyd operon protein YbgE
YPSIP31758_RS15665	COG4890	Cyd operon protein YbgT
YPSIP31758_RS15670	COG1294	oxidase, subunit
YPSIP31758_RS15675	COG1271	oxidase subunit
YPSIP31758_RS15685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPSIP31758_RS15695	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPSIP31758_RS15700	COG0567	Dehydrogenase, E1 component
YPSIP31758_RS15710	COG1053	succinate dehydrogenase
YPSIP31758_RS15715	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPSIP31758_RS15720	COG2009	succinate dehydrogenase
YPSIP31758_RS15735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YPSIP31758_RS15740	COG0497	DNA recombination
YPSIP31758_RS15745	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPSIP31758_RS15755	COG2867	negative regulation of translational initiation
YPSIP31758_RS15765	COG0582	viral genome integration into host DNA
YPSIP31758_RS15770	COG2963	transposase activity
YPSIP31758_RS15775	COG0582	viral genome integration into host DNA
YPSIP31758_RS15785	COG0596	Alpha beta hydrolase
YPSIP31758_RS15810	COG0735	belongs to the Fur family
YPSIP31758_RS15830	COG1263	PTS System
YPSIP31758_RS15830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPSIP31758_RS15830	COG2190	(PTS) system
YPSIP31758_RS15840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPSIP31758_RS15845	COG1940	carbohydrate kinase activity
YPSIP31758_RS15845	COG1846	Transcriptional regulator
YPSIP31758_RS15850	COG0647	UMP catabolic process
YPSIP31758_RS15855	COG0367	asparagine synthase
YPSIP31758_RS15895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPSIP31758_RS15905	COG1702	phosphate starvation-inducible protein PhoH
YPSIP31758_RS15915	COG4535	Mg2 and Co2 transporter CorC
YPSIP31758_RS15920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPSIP31758_RS15930	COG0765	amino acid transport
YPSIP31758_RS15935	COG0765	amino acid transport
YPSIP31758_RS15940	COG1126	abc transporter atp-binding protein
YPSIP31758_RS15945	COG2888	peptidyl-tyrosine sulfation
YPSIP31758_RS15960	COG1466	dna polymerase III delta subunit
YPSIP31758_RS16060	COG0582	viral genome integration into host DNA
YPSIP31758_RS16065	COG0799	negative regulation of ribosome biogenesis
YPSIP31758_RS16075	COG0768	penicillin binding
YPSIP31758_RS16080	COG0772	Belongs to the SEDS family
YPSIP31758_RS16085	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPSIP31758_RS16090	COG1686	Belongs to the peptidase S11 family
YPSIP31758_RS16110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPSIP31758_RS16130	COG1278	Cold shock
YPSIP31758_RS16135	COG2197	response regulator
YPSIP31758_RS16160	COG5265	(ABC) transporter
YPSIP31758_RS16170	COG3718	enzyme involved in inositol metabolism
YPSIP31758_RS16180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPSIP31758_RS16185	COG0673	inositol 2-dehydrogenase activity
YPSIP31758_RS16190	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS16195	COG1129	ABC transporter
YPSIP31758_RS16205	COG0673	inositol 2-dehydrogenase activity
YPSIP31758_RS16210	COG3962	Belongs to the TPP enzyme family
YPSIP31758_RS16225	COG2373	Large extracellular alpha-helical protein
YPSIP31758_RS16230	COG4953	penicillin-binding protein 1C
YPSIP31758_RS16235	COG3423	Transcriptional regulator
YPSIP31758_RS16275	COG2850	peptidyl-arginine hydroxylation
YPSIP31758_RS16280	COG1187	pseudouridine synthase activity
YPSIP31758_RS16295	COG1472	Belongs to the glycosyl hydrolase 3 family
YPSIP31758_RS16315	COG0656	L-ascorbic acid biosynthetic process
YPSIP31758_RS16320	COG0667	Aldo Keto reductase
YPSIP31758_RS16345	COG2453	phosphatase
YPSIP31758_RS16345	COG0671	phosphoesterase, PA-phosphatase related
YPSIP31758_RS16350	COG2267	carboxylic ester hydrolase activity
YPSIP31758_RS16360	COG4589	Belongs to the CDS family
YPSIP31758_RS16365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPSIP31758_RS16410	COG2501	S4 domain
YPSIP31758_RS16420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPSIP31758_RS16430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPSIP31758_RS16435	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPSIP31758_RS16440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPSIP31758_RS16445	COG4181	ATPase activity
YPSIP31758_RS16450	COG2755	lipolytic protein G-D-S-L family
YPSIP31758_RS16455	COG0300	oxidoreductase activity
YPSIP31758_RS16460	COG3118	belongs to the thioredoxin family
YPSIP31758_RS16465	COG0330	HflC and HflK could
YPSIP31758_RS16470	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPSIP31758_RS16475	COG0789	Transcriptional regulator
YPSIP31758_RS16480	COG2217	Heavy metal translocating P-type atpase
YPSIP31758_RS16485	COG3735	TraB family
YPSIP31758_RS16490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPSIP31758_RS16505	COG0737	Belongs to the 5'-nucleotidase family
YPSIP31758_RS16510	COG2223	nitrite transmembrane transporter activity
YPSIP31758_RS16515	COG4651	solute:proton antiporter activity
YPSIP31758_RS16515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPSIP31758_RS16520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPSIP31758_RS16525	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPSIP31758_RS16545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPSIP31758_RS16550	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YPSIP31758_RS16590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPSIP31758_RS16640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPSIP31758_RS16665	COG1196	nuclear chromosome segregation
YPSIP31758_RS16665	COG3264	Mechanosensitive ion channel
YPSIP31758_RS16670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPSIP31758_RS16675	COG1309	transcriptional regulator
YPSIP31758_RS16680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPSIP31758_RS16685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPSIP31758_RS16695	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPSIP31758_RS16715	COG3695	enzyme binding
YPSIP31758_RS16720	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPSIP31758_RS16725	COG1946	Acyl-CoA thioesterase
YPSIP31758_RS16730	COG0004	ammonium transporteR
YPSIP31758_RS16735	COG0347	Belongs to the P(II) protein family
YPSIP31758_RS16740	COG1132	(ABC) transporter
YPSIP31758_RS16745	COG1132	(ABC) transporter
YPSIP31758_RS16750	COG1522	sequence-specific DNA binding
YPSIP31758_RS16765	COG4533	DNA binding
YPSIP31758_RS16775	COG0824	Thioesterase
YPSIP31758_RS16780	COG1555	photosystem II stabilization
YPSIP31758_RS16785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPSIP31758_RS16790	COG0776	regulation of translation
YPSIP31758_RS16795	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPSIP31758_RS16820	COG0271	Belongs to the BolA IbaG family
YPSIP31758_RS16825	COG3056	Lipoprotein
YPSIP31758_RS16830	COG2223	nitrite transmembrane transporter activity
YPSIP31758_RS16840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPSIP31758_RS16845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPSIP31758_RS16850	COG1845	cytochrome c oxidase, subunit III
YPSIP31758_RS16855	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPSIP31758_RS16865	COG2814	Major facilitator Superfamily
YPSIP31758_RS16875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPSIP31758_RS16880	COG0693	protein deglycase activity
YPSIP31758_RS16900	COG0142	geranyltranstransferase activity
YPSIP31758_RS16910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPSIP31758_RS16915	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPSIP31758_RS16930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPSIP31758_RS16930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPSIP31758_RS16950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPSIP31758_RS16955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPSIP31758_RS16960	COG1862	Preprotein translocase
YPSIP31758_RS16980	COG0450	alkyl hydroperoxide reductase
YPSIP31758_RS17000	COG0300	oxidoreductase activity
YPSIP31758_RS17005	COG0366	Alpha amylase catalytic
YPSIP31758_RS17025	COG5002	protein histidine kinase activity
YPSIP31758_RS17030	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS17040	COG0420	3'-5' exonuclease activity
YPSIP31758_RS17045	COG0419	ATPase involved in DNA repair
YPSIP31758_RS17050	COG1940	carbohydrate kinase activity
YPSIP31758_RS17085	COG2226	methyltransferase
YPSIP31758_RS17145	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPSIP31758_RS17165	COG1477	protein flavinylation
YPSIP31758_RS17185	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPSIP31758_RS17190	COG1805	sodium ion transport
YPSIP31758_RS17200	COG3034	peptidoglycan biosynthetic process
YPSIP31758_RS17205	COG0121	glutamine amidotransferase
YPSIP31758_RS17215	COG1960	acyl-CoA dehydrogenase activity
YPSIP31758_RS17225	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPSIP31758_RS17265	COG0436	Aminotransferase
YPSIP31758_RS17280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPSIP31758_RS17290	COG0765	amino acid transport
YPSIP31758_RS17330	COG2814	Major facilitator Superfamily
YPSIP31758_RS17335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPSIP31758_RS17345	COG1846	Transcriptional regulator
YPSIP31758_RS17350	COG1566	PFAM secretion protein HlyD family protein
YPSIP31758_RS17355	COG2814	Major facilitator Superfamily
YPSIP31758_RS17360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPSIP31758_RS17365	COG3118	belongs to the thioredoxin family
YPSIP31758_RS17370	COG3148	PFAM DTW domain containing protein
YPSIP31758_RS17375	COG0045	succinate-CoA ligase (ADP-forming) activity
YPSIP31758_RS17375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPSIP31758_RS17375	COG1042	CoA-binding domain protein
YPSIP31758_RS17380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPSIP31758_RS17385	COG5544	Lipoprotein
YPSIP31758_RS17420	COG0542	response to heat
YPSIP31758_RS17430	COG0564	pseudouridine synthase activity
YPSIP31758_RS17435	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPSIP31758_RS17440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPSIP31758_RS17445	COG0077	Prephenate dehydratase
YPSIP31758_RS17445	COG1605	Chorismate mutase
YPSIP31758_RS17450	COG0287	Prephenate dehydrogenase
YPSIP31758_RS17450	COG1605	Chorismate mutase
YPSIP31758_RS17455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPSIP31758_RS17460	COG3279	Response regulator of the LytR AlgR family
YPSIP31758_RS17465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPSIP31758_RS17470	COG3137	Salt-induced outer membrane protein
YPSIP31758_RS17505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPSIP31758_RS17510	COG4137	Cytochrome C assembly protein
YPSIP31758_RS17515	COG4536	flavin adenine dinucleotide binding
YPSIP31758_RS17530	COG1238	metal cluster binding
YPSIP31758_RS17535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPSIP31758_RS17560	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPSIP31758_RS17600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPSIP31758_RS17605	COG3958	Transketolase
YPSIP31758_RS17610	COG3959	Transketolase, thiamine diphosphate binding domain
YPSIP31758_RS17615	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS17620	COG1129	ABC transporter
YPSIP31758_RS17630	COG1879	ABC-type sugar transport system periplasmic component
YPSIP31758_RS17640	COG3783	Cytochrome b(562)
YPSIP31758_RS17645	COG3038	cytochrome b561
YPSIP31758_RS17650	COG3381	protein complex oligomerization
YPSIP31758_RS17655	COG3302	dmso reductase anchor subunit
YPSIP31758_RS17660	COG0437	4 iron, 4 sulfur cluster binding
YPSIP31758_RS17665	COG0243	molybdopterin cofactor binding
YPSIP31758_RS17670	COG0235	Class ii aldolase
YPSIP31758_RS17675	COG1349	DNA-binding transcription factor activity
YPSIP31758_RS17685	COG1129	ABC transporter
YPSIP31758_RS17690	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS17695	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS17700	COG3623	hexulose-6-phosphate isomerase
YPSIP31758_RS17705	COG1070	Carbohydrate kinase
YPSIP31758_RS17710	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPSIP31758_RS17710	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPSIP31758_RS17720	COG0024	Methionine aminopeptidase
YPSIP31758_RS17730	COG4771	TonB-dependent receptor
YPSIP31758_RS17740	COG1858	cytochrome C peroxidase
YPSIP31758_RS17745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPSIP31758_RS17765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPSIP31758_RS17780	COG2376	Dihydroxyacetone kinase
YPSIP31758_RS17785	COG1028	Short-chain dehydrogenase reductase Sdr
YPSIP31758_RS17790	COG1063	alcohol dehydrogenase
YPSIP31758_RS17795	COG0698	ribose 5-phosphate isomerase
YPSIP31758_RS17810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPSIP31758_RS17815	COG1388	LysM domain
YPSIP31758_RS17815	COG4942	peptidase
YPSIP31758_RS17855	COG0529	Catalyzes the synthesis of activated sulfate
YPSIP31758_RS17905	COG0720	synthase
YPSIP31758_RS17910	COG0602	queuosine metabolic process
YPSIP31758_RS17930	COG3956	TIGRFAM MazG family protein
YPSIP31758_RS17940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPSIP31758_RS17945	COG2205	protein histidine kinase activity
YPSIP31758_RS17945	COG3437	response regulator, receiver
YPSIP31758_RS17945	COG3850	Histidine kinase
YPSIP31758_RS17945	COG4999	Histidine kinase
YPSIP31758_RS17950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPSIP31758_RS17970	COG2860	membrane
YPSIP31758_RS17990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPSIP31758_RS17995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPSIP31758_RS18000	COG1120	ATPase activity
YPSIP31758_RS18005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPSIP31758_RS18010	COG1643	Atp-dependent helicase
YPSIP31758_RS18015	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPSIP31758_RS18030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YPSIP31758_RS18035	COG0617	tRNA 3'-terminal CCA addition
YPSIP31758_RS18040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPSIP31758_RS18060	COG0726	polysaccharide deacetylase
YPSIP31758_RS18065	COG0842	Transport permease protein
YPSIP31758_RS18070	COG1131	(ABC) transporter
YPSIP31758_RS18075	COG0288	reversible hydration of carbon dioxide
YPSIP31758_RS18080	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPSIP31758_RS18085	COG2132	Multicopper oxidase
YPSIP31758_RS18105	COG0697	spore germination
YPSIP31758_RS18115	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPSIP31758_RS18120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPSIP31758_RS18125	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPSIP31758_RS18130	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPSIP31758_RS18135	COG2186	Transcriptional regulator
YPSIP31758_RS18140	COG1113	amino acid transport
YPSIP31758_RS18145	COG3725	Membrane protein required for beta-lactamase induction
YPSIP31758_RS18150	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPSIP31758_RS18160	COG4969	Belongs to the N-Me-Phe pilin family
YPSIP31758_RS18165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPSIP31758_RS18170	COG1459	type II secretion system
YPSIP31758_RS18200	COG0494	nUDIX hydrolase
YPSIP31758_RS18225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPSIP31758_RS18230	COG0849	cell division
YPSIP31758_RS18235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPSIP31758_RS18255	COG0772	Belongs to the SEDS family
YPSIP31758_RS18270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPSIP31758_RS18275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPSIP31758_RS18280	COG0768	penicillin binding
YPSIP31758_RS18285	COG3116	cell division
YPSIP31758_RS18310	COG1609	Transcriptional regulator
YPSIP31758_RS18325	COG0028	Belongs to the TPP enzyme family
YPSIP31758_RS18335	COG1022	Amp-dependent synthetase and ligase
YPSIP31758_RS18355	COG0473	3-isopropylmalate dehydrogenase activity
YPSIP31758_RS18370	COG2814	Major facilitator Superfamily
YPSIP31758_RS18400	COG4143	(ABC) transporter
YPSIP31758_RS18405	COG1178	ABC-type Fe3 transport system permease component
YPSIP31758_RS18410	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
YPSIP31758_RS18415	COG0586	Pfam SNARE associated Golgi protein
YPSIP31758_RS18420	COG0417	DNA replication proofreading
YPSIP31758_RS18440	COG3047	cAMP biosynthetic process
YPSIP31758_RS18440	COG2885	chlorophyll binding
YPSIP31758_RS18525	COG0564	pseudouridine synthase activity
YPSIP31758_RS18575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPSIP31758_RS18585	COG2966	Psort location CytoplasmicMembrane, score
YPSIP31758_RS18595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPSIP31758_RS18620	COG1047	Peptidyl-prolyl cis-trans
YPSIP31758_RS18635	COG0196	riboflavin kinase activity
YPSIP31758_RS18650	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS18670	COG1584	GPR1 FUN34 yaaH family protein
YPSIP31758_RS18685	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPSIP31758_RS18715	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS18720	COG3045	CreA protein
YPSIP31758_RS18725	COG2207	Transcriptional regulator
YPSIP31758_RS18725	COG3708	Transcriptional regulator
YPSIP31758_RS18740	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPSIP31758_RS18745	COG0741	lytic transglycosylase activity
YPSIP31758_RS18760	COG2199	diguanylate cyclase activity
YPSIP31758_RS18765	COG2885	chlorophyll binding
YPSIP31758_RS18770	COG0488	(ABC) transporter
YPSIP31758_RS18790	COG0560	Phosphoserine phosphatase
YPSIP31758_RS18795	COG3726	membrane protein affecting hemolysin expression
YPSIP31758_RS18820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPSIP31758_RS18825	COG0084	hydrolase, TatD family'
YPSIP31758_RS18830	COG4667	esterase of the alpha-beta hydrolase superfamily
YPSIP31758_RS18840	COG2823	Periplasmic or secreted lipoprotein
YPSIP31758_RS18850	COG0456	acetyltransferase
YPSIP31758_RS18855	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPSIP31758_RS18910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPSIP31758_RS18915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPSIP31758_RS18935	COG0859	PFAM glycosyl transferase family 9
YPSIP31758_RS18945	COG2390	Transcriptional regulator
YPSIP31758_RS18990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPSIP31758_RS18990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPSIP31758_RS18990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPSIP31758_RS18995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPSIP31758_RS19000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPSIP31758_RS19005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPSIP31758_RS19010	COG2207	Transcriptional regulator
YPSIP31758_RS19020	COG4269	membrane
YPSIP31758_RS19055	COG0795	lipopolysaccharide-transporting ATPase activity
YPSIP31758_RS19060	COG0795	lipopolysaccharide-transporting ATPase activity
YPSIP31758_RS19070	COG2927	DNA polymerase III (CHI subunit)
YPSIP31758_RS19085	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPSIP31758_RS19095	COG2731	YhcH YjgK YiaL family protein
YPSIP31758_RS19105	COG0601	transmembrane transport
YPSIP31758_RS19110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPSIP31758_RS19115	COG0444	Belongs to the ABC transporter superfamily
YPSIP31758_RS19120	COG4608	Belongs to the ABC transporter superfamily
YPSIP31758_RS19135	COG2188	Transcriptional regulator
YPSIP31758_RS19140	COG3624	Phosphonate C-P lyase system protein PhnG
YPSIP31758_RS19145	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPSIP31758_RS19150	COG3626	phosphonate metabolism
YPSIP31758_RS19155	COG3627	carbon phosphorus lyase activity
YPSIP31758_RS19160	COG4107	phosphonate C-P lyase system protein PhnK
YPSIP31758_RS19165	COG4778	phosphonate C-P lyase system protein PhnL
YPSIP31758_RS19170	COG3454	Phosphonate metabolism
YPSIP31758_RS19175	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPSIP31758_RS19180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPSIP31758_RS19185	COG0702	epimerase
YPSIP31758_RS19200	COG3842	ATPase activity
YPSIP31758_RS19205	COG0395	ABC-type sugar transport system, permease component
YPSIP31758_RS19210	COG1175	transmembrane transport
YPSIP31758_RS19215	COG1653	transport
YPSIP31758_RS19235	COG3153	acetyltransferase
YPSIP31758_RS19240	COG3154	lipid carrier protein
YPSIP31758_RS19250	COG0826	peptidase U32
YPSIP31758_RS19255	COG0826	peptidase U32
YPSIP31758_RS19265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPSIP31758_RS19275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPSIP31758_RS19295	COG0513	Belongs to the DEAD box helicase family
YPSIP31758_RS19330	COG0195	Participates in both transcription termination and antitermination
YPSIP31758_RS19350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPSIP31758_RS19360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPSIP31758_RS19375	COG1534	Rna-binding protein
YPSIP31758_RS19385	COG2027	D-alanyl-D-alanine carboxypeptidase
YPSIP31758_RS19390	COG0745	RESPONSE REGULATOR receiver
YPSIP31758_RS19395	COG0642	Histidine kinase
YPSIP31758_RS19405	COG0697	spore germination
YPSIP31758_RS19420	COG0142	geranyltranstransferase activity
YPSIP31758_RS19430	COG3423	Transcriptional regulator
YPSIP31758_RS19455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPSIP31758_RS19465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPSIP31758_RS19470	COG2105	PFAM AIG2 family protein
YPSIP31758_RS19475	COG2911	Protein conserved in bacteria
YPSIP31758_RS19480	COG0729	surface antigen
YPSIP31758_RS19490	COG1253	flavin adenine dinucleotide binding
YPSIP31758_RS19500	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPSIP31758_RS19510	COG0737	Belongs to the 5'-nucleotidase family
YPSIP31758_RS19520	COG0545	Peptidyl-prolyl cis-trans isomerase
YPSIP31758_RS19525	COG3061	Opacity-associated protein A
YPSIP31758_RS19540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPSIP31758_RS19550	COG0360	Binds together with S18 to 16S ribosomal RNA
YPSIP31758_RS19560	COG1073	alpha beta
YPSIP31758_RS19565	COG3650	response to hydrogen peroxide
YPSIP31758_RS19570	COG1960	acyl-CoA dehydrogenase activity
YPSIP31758_RS19575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPSIP31758_RS19580	COG0557	exoribonuclease II activity
YPSIP31758_RS19595	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPSIP31758_RS19600	COG0330	HflC and HflK could
YPSIP31758_RS19605	COG0330	HflC and HflK could
YPSIP31758_RS19610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPSIP31758_RS19630	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPSIP31758_RS19635	COG0802	atpase or kinase
YPSIP31758_RS19640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPSIP31758_RS19640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPSIP31758_RS19645	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPSIP31758_RS19690	COG3264	Mechanosensitive ion channel
YPSIP31758_RS19690	COG1511	domain protein
YPSIP31758_RS19705	COG1053	succinate dehydrogenase
YPSIP31758_RS19710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPSIP31758_RS19720	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPSIP31758_RS19765	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPSIP31758_RS19780	COG3383	formate dehydrogenase (NAD+) activity
YPSIP31758_RS19785	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPSIP31758_RS19790	COG0493	'glutamate synthase
YPSIP31758_RS19790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPSIP31758_RS19795	COG1309	transcriptional regulator
YPSIP31758_RS19850	COG3209	COG3209 Rhs family protein
YPSIP31758_RS20100	COG0305	Participates in initiation and elongation during chromosome replication
YPSIP31758_RS20170	COG1454	alcohol dehydrogenase
YPSIP31758_RS20180	COG0629	single-stranded DNA binding
YPSIP31758_RS20185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPSIP31758_RS20190	COG2315	Protein conserved in bacteria
YPSIP31758_RS20195	COG1448	Aminotransferase
YPSIP31758_RS20220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPSIP31758_RS20225	COG0735	belongs to the Fur family
YPSIP31758_RS20235	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPSIP31758_RS20280	COG3121	Chaperone
YPSIP31758_RS20340	COG1358	cellular component organization or biogenesis
YPSIP31758_RS20365	COG3721	Heme iron utilization protein
YPSIP31758_RS20370	COG0702	epimerase
YPSIP31758_RS20380	COG4771	TonB-dependent receptor
YPSIP31758_RS20385	COG3720	iron ion transport
YPSIP31758_RS20390	COG4558	Periplasmic binding protein
YPSIP31758_RS20395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPSIP31758_RS20405	COG0626	cystathionine gamma-synthase activity
YPSIP31758_RS20410	COG0814	amino acid
YPSIP31758_RS20415	COG0583	DNA-binding transcription factor activity
YPSIP31758_RS20420	COG0425	Belongs to the sulfur carrier protein TusA family
YPSIP31758_RS20425	COG2391	methyltransferase activity
YPSIP31758_RS20535	COG1301	dicarboxylic acid transport
YPSIP31758_RS20545	COG3162	membrane
YPSIP31758_RS20595	COG0151	Belongs to the GarS family
YPSIP31758_RS20655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPSIP31758_RS20715	COG0250	Participates in transcription elongation, termination and antitermination
YPSIP31758_RS20805	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPSIP31758_RS20820	COG0551	DNA topoisomerase type I activity
YPSIP31758_RS20830	COG0758	DNA mediated transformation
YPSIP31758_RS20860	COG3036	rescue of stalled ribosome
YPSIP31758_RS20865	COG0789	Transcriptional regulator
YPSIP31758_RS20880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPSIP31758_RS20895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPSIP31758_RS20900	COG0201	protein transport
YPSIP31758_RS20910	COG1841	ribosomal large subunit assembly
YPSIP31758_RS20950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPSIP31758_RS20970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPSIP31758_RS20975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPSIP31758_RS20985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPSIP31758_RS20995	COG0089	rRNA binding
YPSIP31758_RS21010	COG0051	transcription antitermination factor activity, RNA binding
YPSIP31758_RS21035	COG0049	tRNA binding
YPSIP31758_RS21040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPSIP31758_RS21060	COG2964	Protein conserved in bacteria
YPSIP31758_RS21065	COG0545	Peptidyl-prolyl cis-trans isomerase
YPSIP31758_RS21075	COG1047	Peptidyl-prolyl cis-trans
YPSIP31758_RS21080	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPSIP31758_RS21095	COG0488	(ABC) transporter
YPSIP31758_RS21100	COG1216	Glycosyl transferase, family 2
YPSIP31758_RS21110	COG2175	clavaminate synthase activity
YPSIP31758_RS21115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPSIP31758_RS21125	COG4521	taurine ABC transporter
YPSIP31758_RS21135	COG0429	hydrolase of the alpha beta-hydrolase fold
YPSIP31758_RS21145	COG3954	Phosphoribulokinase
YPSIP31758_RS21155	COG1765	OsmC-like protein
YPSIP31758_RS21165	COG1289	transmembrane transporter activity
YPSIP31758_RS21180	COG0433	COG0433 Predicted ATPase
YPSIP31758_RS21185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPSIP31758_RS21190	COG1486	melibiose metabolic process
YPSIP31758_RS21210	COG0402	S-adenosylhomocysteine deaminase activity
YPSIP31758_RS21215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPSIP31758_RS21235	COG0180	Tryptophanyl-tRNA synthetase
YPSIP31758_RS21240	COG0546	phosphoglycolate phosphatase activity
YPSIP31758_RS21245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPSIP31758_RS21270	COG4796	Type ii and iii secretion system protein
YPSIP31758_RS21300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPSIP31758_RS21305	COG0494	nUDIX hydrolase
YPSIP31758_RS21320	COG1011	Hydrolase
YPSIP31758_RS21325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPSIP31758_RS21350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPSIP31758_RS21355	COG2183	response to ionizing radiation
YPSIP31758_RS21365	COG1918	ferrous iron import across plasma membrane
YPSIP31758_RS21400	COG1640	4-alpha-glucanotransferase
YPSIP31758_RS21405	COG0058	SHG alpha-glucan phosphorylase activity
YPSIP31758_RS21425	COG1349	DNA-binding transcription factor activity
YPSIP31758_RS21445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPSIP31758_RS21450	COG0058	SHG alpha-glucan phosphorylase activity
YPSIP31758_RS21475	COG3275	phosphorelay sensor kinase activity
YPSIP31758_RS21500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPSIP31758_RS21505	COG2095	MarC family integral membrane protein
YPSIP31758_RS21540	COG3265	gluconokinase activity
YPSIP31758_RS21545	COG2610	gluconate transmembrane transporter activity
YPSIP31758_RS21550	COG1609	Transcriptional regulator
YPSIP31758_RS21555	COG1741	Belongs to the pirin family
YPSIP31758_RS21575	COG0191	fructose-bisphosphate aldolase activity
YPSIP31758_RS21590	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPSIP31758_RS21605	COG2081	HI0933 family
YPSIP31758_RS21610	COG0306	phosphate transporter
YPSIP31758_RS21620	COG0589	response to stress
YPSIP31758_RS21670	COG0339	signal peptide processing
YPSIP31758_RS21675	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPSIP31758_RS21680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPSIP31758_RS21685	COG3835	regulator
YPSIP31758_RS21690	COG2610	gluconate transmembrane transporter activity
YPSIP31758_RS21695	COG1929	Belongs to the glycerate kinase type-1 family
YPSIP31758_RS21715	COG1295	ribonuclease BN
YPSIP31758_RS21720	COG2134	cdp-diacylglycerol pyrophosphatase
YPSIP31758_RS21725	COG2982	Protein involved in outer membrane biogenesis
YPSIP31758_RS21730	COG2200	EAL domain
YPSIP31758_RS21735	COG1942	4-Oxalocrotonate Tautomerase
YPSIP31758_RS21740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPSIP31758_RS21745	COG0612	Peptidase, M16
YPSIP31758_RS21765	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPSIP31758_RS21770	COG2200	EAL domain
YPSIP31758_RS21770	COG2199	diguanylate cyclase activity
YPSIP31758_RS21775	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPSIP31758_RS21780	COG4608	Belongs to the ABC transporter superfamily
YPSIP31758_RS21785	COG0444	Belongs to the ABC transporter superfamily
YPSIP31758_RS21790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPSIP31758_RS21795	COG0601	transmembrane transport
YPSIP31758_RS21800	COG0747	negative chemotaxis
YPSIP31758_RS21810	COG2831	hemolysin activation secretion protein
YPSIP31758_RS21815	COG3210	domain, Protein
YPSIP31758_RS21825	COG2271	Major facilitator Superfamily
YPSIP31758_RS21830	COG3851	Histidine kinase
YPSIP31758_RS21835	COG2197	response regulator
YPSIP31758_RS21840	COG2194	sulfuric ester hydrolase activity
YPSIP31758_RS21885	COG4607	ABC-type enterochelin transport system periplasmic component
YPSIP31758_RS21895	COG4605	iron ion homeostasis
YPSIP31758_RS21900	COG4604	ABC transporter, ATP-binding protein
YPSIP31758_RS21915	COG1609	Transcriptional regulator
YPSIP31758_RS21915	COG2207	Transcriptional regulator
YPSIP31758_RS21920	COG4214	carbohydrate transport
YPSIP31758_RS21930	COG4213	ABC transporter substrate-binding protein
YPSIP31758_RS21940	COG1070	Carbohydrate kinase
YPSIP31758_RS21950	COG3121	Chaperone
YPSIP31758_RS21955	COG3188	usher protein
YPSIP31758_RS21960	COG3539	Fimbrial protein
YPSIP31758_RS21965	COG3274	enterobacterial common antigen metabolic process
YPSIP31758_RS21995	COG3276	selenocysteine insertion sequence binding
YPSIP31758_RS22010	COG2864	formate dehydrogenase
YPSIP31758_RS22015	COG0437	4 iron, 4 sulfur cluster binding
YPSIP31758_RS22020	COG3383	formate dehydrogenase (NAD+) activity
YPSIP31758_RS22020	COG0243	molybdopterin cofactor binding
YPSIP31758_RS22025	COG3383	formate dehydrogenase (NAD+) activity
YPSIP31758_RS22025	COG0243	molybdopterin cofactor binding
YPSIP31758_RS22035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPSIP31758_RS22060	COG3722	fumarate hydratase activity
YPSIP31758_RS22070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPSIP31758_RS22070	COG2213	PTS system mannitol-specific
YPSIP31758_RS22090	COG2818	Glycosylase
YPSIP31758_RS22100	COG2885	chlorophyll binding
YPSIP31758_RS22115	COG0366	Alpha amylase catalytic
YPSIP31758_RS22130	COG3977	Valine--pyruvate aminotransferase
YPSIP31758_RS22150	COG5645	(Lipo)protein
YPSIP31758_RS22155	COG0823	Involved in the tonB-independent uptake of proteins
YPSIP31758_RS22160	COG0823	Involved in the tonB-independent uptake of proteins
YPSIP31758_RS22165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPSIP31758_RS22170	COG2423	ornithine cyclodeaminase activity
YPSIP31758_RS22180	COG0561	phosphatase activity
YPSIP31758_RS22185	COG0187	DNA topoisomerase II activity
YPSIP31758_RS22200	COG0592	DNA-directed DNA polymerase activity
YPSIP31758_RS22210	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPSIP31758_RS22220	COG0706	membrane insertase activity
YPSIP31758_RS22235	COG2252	PERMEase
YPSIP31758_RS22240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPSIP31758_RS22245	COG0765	amino acid transport
YPSIP31758_RS22250	COG0765	amino acid transport
YPSIP31758_RS22255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPSIP31758_RS22265	COG0704	Plays a role in the regulation of phosphate uptake
YPSIP31758_RS22275	COG0581	inorganic phosphate transmembrane transporter activity
YPSIP31758_RS22280	COG0573	inorganic phosphate transmembrane transporter activity
YPSIP31758_RS22285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPSIP31758_RS22340	COG3312	ion transport
YPSIP31758_RS22535	COG3210	domain, Protein
YPSIP31758_RS22565	COG3210	domain, Protein