locus-tag	class	description
YPTS_RS00010	COG0592	DNA-directed DNA polymerase activity
YPTS_RS00025	COG0187	DNA topoisomerase II activity
YPTS_RS00030	COG0561	phosphatase activity
YPTS_RS00040	COG2801	Transposase and inactivated derivatives
YPTS_RS00070	COG3328	transposase activity
YPTS_RS00075	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPTS_RS00085	COG3084	Protein conserved in bacteria
YPTS_RS00090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPTS_RS00095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPTS_RS00100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPTS_RS00100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPTS_RS00115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPTS_RS00125	COG3852	Histidine kinase
YPTS_RS00130	COG0174	glutamine synthetase
YPTS_RS00145	COG1011	Hydrolase
YPTS_RS00160	COG0456	acetyltransferase
YPTS_RS00165	COG2982	Protein involved in outer membrane biogenesis
YPTS_RS00170	COG2233	PERMEase
YPTS_RS00175	COG0786	glutamate:sodium symporter activity
YPTS_RS00180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPTS_RS00185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPTS_RS00190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPTS_RS00195	COG1758	RNA polymerase activity
YPTS_RS00210	COG2860	membrane
YPTS_RS00215	COG1561	YicC-like family, N-terminal region
YPTS_RS00240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPTS_RS00275	COG1519	Transferase
YPTS_RS00280	COG0859	PFAM glycosyl transferase family 9
YPTS_RS00285	COG0859	PFAM glycosyl transferase family 9
YPTS_RS00295	COG0156	8-amino-7-oxononanoate synthase activity
YPTS_RS00305	COG2861	carbohydrate metabolic process
YPTS_RS00310	COG4942	peptidase
YPTS_RS00320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPTS_RS00325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPTS_RS00345	COG1045	serine acetyltransferase
YPTS_RS00350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPTS_RS00355	COG2169	Transcriptional regulator
YPTS_RS00355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPTS_RS00360	COG2205	protein histidine kinase activity
YPTS_RS00365	COG0745	RESPONSE REGULATOR receiver
YPTS_RS00370	COG3678	ATP-independent chaperone mediated protein folding
YPTS_RS00390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPTS_RS00400	COG0471	metal ion transport
YPTS_RS00405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPTS_RS00410	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPTS_RS00415	COG0583	DNA-binding transcription factor activity
YPTS_RS00430	COG3152	Membrane
YPTS_RS00440	COG1494	fructose-1,6-bisphosphatase
YPTS_RS00445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPTS_RS00450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPTS_RS00495	COG1575	Belongs to the MenA family. Type 1 subfamily
YPTS_RS00510	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPTS_RS00515	COG1609	Transcriptional regulator
YPTS_RS00525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPTS_RS00535	COG4682	membrane
YPTS_RS00545	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YPTS_RS00550	COG0626	cystathionine gamma-synthase activity
YPTS_RS00555	COG0460	homoserine dehydrogenase
YPTS_RS00555	COG0527	aspartate kinase activity
YPTS_RS00600	COG1629	transport
YPTS_RS00625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPTS_RS00630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPTS_RS00630	COG0678	peroxiredoxin activity
YPTS_RS00710	COG1879	ABC-type sugar transport system periplasmic component
YPTS_RS00715	COG1129	ABC transporter
YPTS_RS00720	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS00725	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS00735	COG3085	chromosome segregation
YPTS_RS00750	COG3978	acetolactate synthase activity
YPTS_RS00755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPTS_RS00795	COG0583	DNA-binding transcription factor activity
YPTS_RS00865	COG3121	Chaperone
YPTS_RS00880	COG3121	Chaperone
YPTS_RS00900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPTS_RS00925	COG3118	belongs to the thioredoxin family
YPTS_RS00930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPTS_RS00935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPTS_RS00940	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPTS_RS00945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPTS_RS00950	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPTS_RS00955	COG1088	dTDP-glucose 4,6-dehydratase activity
YPTS_RS00960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPTS_RS00965	COG0456	acetyltransferase
YPTS_RS00970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPTS_RS00975	COG2244	polysaccharide biosynthetic process
YPTS_RS00995	COG1113	amino acid transport
YPTS_RS01020	COG3071	HemY protein
YPTS_RS01025	COG2959	enzyme of heme biosynthesis
YPTS_RS01030	COG1587	Uroporphyrinogen-III synthase
YPTS_RS01040	COG3072	Adenylate cyclase
YPTS_RS01050	COG3328	transposase activity
YPTS_RS01075	COG3159	Protein conserved in bacteria
YPTS_RS01080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPTS_RS01085	COG1011	Hydrolase
YPTS_RS01090	COG0210	DNA helicase
YPTS_RS01100	COG5441	Belongs to the UPF0261 family
YPTS_RS01105	COG5564	TIM-barrel signal transduction protein
YPTS_RS01120	COG2050	protein possibly involved in aromatic compounds catabolism
YPTS_RS01125	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPTS_RS01130	COG0514	ATP-dependent DNA helicase (RecQ)
YPTS_RS01135	COG1280	lysine exporter protein (LysE YggA)
YPTS_RS01140	COG1280	lysine exporter protein (LysE YggA)
YPTS_RS01145	COG2267	carboxylic ester hydrolase activity
YPTS_RS01150	COG0561	phosphatase activity
YPTS_RS01160	COG0584	glycerophosphoryl diester phosphodiesterase
YPTS_RS01170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPTS_RS01180	COG0247	lactate metabolic process
YPTS_RS01190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPTS_RS01205	COG3714	YhhN family
YPTS_RS01220	COG3776	membrane
YPTS_RS01225	COG0742	ribosomal rna small subunit methyltransferase
YPTS_RS01235	COG0552	protein localization to endoplasmic reticulum
YPTS_RS01235	COG0552	protein localization to endoplasmic reticulum
YPTS_RS01240	COG2884	Cell division ATP-binding protein ftsE
YPTS_RS01245	COG2177	Part of the ABC transporter FtsEX involved in
YPTS_RS01260	COG0683	leucine binding
YPTS_RS01270	COG4177	L-phenylalanine transmembrane transporter activity
YPTS_RS01280	COG0410	ABC transporter
YPTS_RS01340	COG0584	glycerophosphoryl diester phosphodiesterase
YPTS_RS01345	COG0679	Auxin Efflux Carrier
YPTS_RS01360	COG0697	spore germination
YPTS_RS01365	COG0583	DNA-binding transcription factor activity
YPTS_RS01375	COG0412	Dienelactone hydrolase
YPTS_RS01390	COG1966	Carbon starvation protein
YPTS_RS01395	COG0586	Pfam SNARE associated Golgi protein
YPTS_RS01400	COG1322	Protein conserved in bacteria
YPTS_RS01420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPTS_RS01430	COG0805	protein transport
YPTS_RS01475	COG1739	Uncharacterized protein family UPF0029
YPTS_RS01480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPTS_RS01485	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPTS_RS01570	COG0250	Participates in transcription elongation, termination and antitermination
YPTS_RS01625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPTS_RS01665	COG1515	deoxyribonuclease V activity
YPTS_RS01685	COG0151	Belongs to the GarS family
YPTS_RS01725	COG2801	Transposase and inactivated derivatives
YPTS_RS01750	COG3162	membrane
YPTS_RS01760	COG1301	dicarboxylic acid transport
YPTS_RS01765	COG2197	response regulator
YPTS_RS01870	COG2391	methyltransferase activity
YPTS_RS01875	COG0425	Belongs to the sulfur carrier protein TusA family
YPTS_RS01880	COG0583	DNA-binding transcription factor activity
YPTS_RS01885	COG0814	amino acid
YPTS_RS01890	COG0626	cystathionine gamma-synthase activity
YPTS_RS01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_RS01905	COG4558	Periplasmic binding protein
YPTS_RS01910	COG3720	iron ion transport
YPTS_RS01915	COG4771	TonB-dependent receptor
YPTS_RS01925	COG0702	epimerase
YPTS_RS01930	COG3721	Heme iron utilization protein
YPTS_RS01955	COG1358	cellular component organization or biogenesis
YPTS_RS02015	COG3121	Chaperone
YPTS_RS02060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPTS_RS02070	COG0735	belongs to the Fur family
YPTS_RS02075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPTS_RS02100	COG1448	Aminotransferase
YPTS_RS02105	COG2315	Protein conserved in bacteria
YPTS_RS02110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPTS_RS02115	COG0629	single-stranded DNA binding
YPTS_RS02125	COG1454	alcohol dehydrogenase
YPTS_RS02195	COG1309	transcriptional regulator
YPTS_RS02200	COG0493	'glutamate synthase
YPTS_RS02200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_RS02205	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_RS02210	COG3383	formate dehydrogenase (NAD+) activity
YPTS_RS02225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPTS_RS02270	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPTS_RS02280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPTS_RS02285	COG1053	succinate dehydrogenase
YPTS_RS02300	COG3264	Mechanosensitive ion channel
YPTS_RS02300	COG1511	domain protein
YPTS_RS02345	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPTS_RS02350	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPTS_RS02350	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPTS_RS02355	COG0802	atpase or kinase
YPTS_RS02360	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPTS_RS02380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPTS_RS02385	COG0330	HflC and HflK could
YPTS_RS02390	COG0330	HflC and HflK could
YPTS_RS02395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPTS_RS02410	COG0557	exoribonuclease II activity
YPTS_RS02415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPTS_RS02420	COG1960	acyl-CoA dehydrogenase activity
YPTS_RS02425	COG3650	response to hydrogen peroxide
YPTS_RS02430	COG1073	alpha beta
YPTS_RS02440	COG0360	Binds together with S18 to 16S ribosomal RNA
YPTS_RS02450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPTS_RS02465	COG3061	Opacity-associated protein A
YPTS_RS02470	COG0545	Peptidyl-prolyl cis-trans isomerase
YPTS_RS02480	COG0737	Belongs to the 5'-nucleotidase family
YPTS_RS02490	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPTS_RS02500	COG1253	flavin adenine dinucleotide binding
YPTS_RS02510	COG0729	surface antigen
YPTS_RS02515	COG2911	Protein conserved in bacteria
YPTS_RS02520	COG2105	PFAM AIG2 family protein
YPTS_RS02525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPTS_RS02535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPTS_RS02560	COG3423	Transcriptional regulator
YPTS_RS02570	COG0142	geranyltranstransferase activity
YPTS_RS02585	COG0697	spore germination
YPTS_RS02595	COG0642	Histidine kinase
YPTS_RS02600	COG0745	RESPONSE REGULATOR receiver
YPTS_RS02605	COG2027	D-alanyl-D-alanine carboxypeptidase
YPTS_RS02615	COG1534	Rna-binding protein
YPTS_RS02630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPTS_RS02640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPTS_RS02660	COG0195	Participates in both transcription termination and antitermination
YPTS_RS02695	COG0513	Belongs to the DEAD box helicase family
YPTS_RS02715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPTS_RS02725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPTS_RS02735	COG0826	peptidase U32
YPTS_RS02740	COG0826	peptidase U32
YPTS_RS02750	COG3154	lipid carrier protein
YPTS_RS02755	COG3153	acetyltransferase
YPTS_RS02780	COG1653	transport
YPTS_RS02785	COG1175	transmembrane transport
YPTS_RS02790	COG0395	ABC-type sugar transport system, permease component
YPTS_RS02795	COG3842	ATPase activity
YPTS_RS02810	COG0702	epimerase
YPTS_RS02815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPTS_RS02820	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPTS_RS02825	COG3454	Phosphonate metabolism
YPTS_RS02830	COG4778	phosphonate C-P lyase system protein PhnL
YPTS_RS02835	COG4107	phosphonate C-P lyase system protein PhnK
YPTS_RS02840	COG3627	carbon phosphorus lyase activity
YPTS_RS02845	COG3626	phosphonate metabolism
YPTS_RS02850	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPTS_RS02855	COG3624	Phosphonate C-P lyase system protein PhnG
YPTS_RS02860	COG2188	Transcriptional regulator
YPTS_RS02875	COG4608	Belongs to the ABC transporter superfamily
YPTS_RS02880	COG0444	Belongs to the ABC transporter superfamily
YPTS_RS02885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPTS_RS02890	COG0601	transmembrane transport
YPTS_RS02900	COG2731	YhcH YjgK YiaL family protein
YPTS_RS02910	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPTS_RS02925	COG2927	DNA polymerase III (CHI subunit)
YPTS_RS02935	COG0795	lipopolysaccharide-transporting ATPase activity
YPTS_RS02940	COG0795	lipopolysaccharide-transporting ATPase activity
YPTS_RS02960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_RS02960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_RS02960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPTS_RS03005	COG2390	Transcriptional regulator
YPTS_RS03015	COG0859	PFAM glycosyl transferase family 9
YPTS_RS03025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPTS_RS03060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_RS03065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPTS_RS03120	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPTS_RS03125	COG0456	acetyltransferase
YPTS_RS03135	COG2823	Periplasmic or secreted lipoprotein
YPTS_RS03145	COG4667	esterase of the alpha-beta hydrolase superfamily
YPTS_RS03150	COG0084	hydrolase, TatD family'
YPTS_RS03155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPTS_RS03180	COG3726	membrane protein affecting hemolysin expression
YPTS_RS03185	COG0560	Phosphoserine phosphatase
YPTS_RS03205	COG0488	(ABC) transporter
YPTS_RS03210	COG2885	chlorophyll binding
YPTS_RS03215	COG2199	diguanylate cyclase activity
YPTS_RS03230	COG0741	lytic transglycosylase activity
YPTS_RS03235	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPTS_RS03250	COG3708	Transcriptional regulator
YPTS_RS03250	COG2207	Transcriptional regulator
YPTS_RS03255	COG3045	CreA protein
YPTS_RS03260	COG0745	RESPONSE REGULATOR receiver
YPTS_RS03290	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPTS_RS03305	COG1584	GPR1 FUN34 yaaH family protein
YPTS_RS03325	COG0583	DNA-binding transcription factor activity
YPTS_RS03340	COG0196	riboflavin kinase activity
YPTS_RS03355	COG1047	Peptidyl-prolyl cis-trans
YPTS_RS03380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPTS_RS03390	COG2966	Psort location CytoplasmicMembrane, score
YPTS_RS03400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPTS_RS03450	COG0564	pseudouridine synthase activity
YPTS_RS03535	COG2885	chlorophyll binding
YPTS_RS03535	COG3047	cAMP biosynthetic process
YPTS_RS03555	COG0417	DNA replication proofreading
YPTS_RS03560	COG0586	Pfam SNARE associated Golgi protein
YPTS_RS03570	COG1178	ABC-type Fe3 transport system permease component
YPTS_RS03575	COG4143	(ABC) transporter
YPTS_RS03605	COG2814	Major facilitator Superfamily
YPTS_RS03645	COG1022	Amp-dependent synthetase and ligase
YPTS_RS03655	COG0028	Belongs to the TPP enzyme family
YPTS_RS03670	COG1609	Transcriptional regulator
YPTS_RS03690	COG3116	cell division
YPTS_RS03695	COG0768	penicillin binding
YPTS_RS03700	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPTS_RS03705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPTS_RS03720	COG0772	Belongs to the SEDS family
YPTS_RS03740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPTS_RS03745	COG0849	cell division
YPTS_RS03750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPTS_RS03775	COG0494	nUDIX hydrolase
YPTS_RS03815	COG3328	transposase activity
YPTS_RS03820	COG1459	type II secretion system
YPTS_RS03825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPTS_RS03830	COG4969	Belongs to the N-Me-Phe pilin family
YPTS_RS03840	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPTS_RS03845	COG3725	Membrane protein required for beta-lactamase induction
YPTS_RS03850	COG1113	amino acid transport
YPTS_RS03855	COG2186	Transcriptional regulator
YPTS_RS03860	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPTS_RS03865	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPTS_RS03870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPTS_RS03875	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPTS_RS03885	COG0697	spore germination
YPTS_RS03905	COG2132	Multicopper oxidase
YPTS_RS03910	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPTS_RS03915	COG0288	reversible hydration of carbon dioxide
YPTS_RS03920	COG1131	(ABC) transporter
YPTS_RS03925	COG0842	Transport permease protein
YPTS_RS03930	COG0726	polysaccharide deacetylase
YPTS_RS03950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPTS_RS03955	COG0617	tRNA 3'-terminal CCA addition
YPTS_RS03975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPTS_RS03980	COG1643	Atp-dependent helicase
YPTS_RS03985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPTS_RS03990	COG1120	ATPase activity
YPTS_RS03995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPTS_RS04000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_RS04020	COG2860	membrane
YPTS_RS04040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPTS_RS04045	COG3850	Histidine kinase
YPTS_RS04045	COG3437	response regulator, receiver
YPTS_RS04045	COG2205	protein histidine kinase activity
YPTS_RS04045	COG4999	Histidine kinase
YPTS_RS04050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPTS_RS04060	COG3956	TIGRFAM MazG family protein
YPTS_RS04080	COG0602	queuosine metabolic process
YPTS_RS04085	COG0720	synthase
YPTS_RS04135	COG0529	Catalyzes the synthesis of activated sulfate
YPTS_RS04175	COG4942	peptidase
YPTS_RS04175	COG1388	LysM domain
YPTS_RS04180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPTS_RS04195	COG0698	ribose 5-phosphate isomerase
YPTS_RS04200	COG1063	alcohol dehydrogenase
YPTS_RS04205	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS04210	COG2376	Dihydroxyacetone kinase
YPTS_RS04225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPTS_RS04245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_RS04250	COG1858	cytochrome C peroxidase
YPTS_RS04260	COG4771	TonB-dependent receptor
YPTS_RS04275	COG0024	Methionine aminopeptidase
YPTS_RS04285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPTS_RS04285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPTS_RS04290	COG1070	Carbohydrate kinase
YPTS_RS04295	COG3623	hexulose-6-phosphate isomerase
YPTS_RS04300	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS04305	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS04310	COG1129	ABC transporter
YPTS_RS04320	COG1349	DNA-binding transcription factor activity
YPTS_RS04325	COG0235	Class ii aldolase
YPTS_RS04330	COG0243	molybdopterin cofactor binding
YPTS_RS04335	COG0437	4 iron, 4 sulfur cluster binding
YPTS_RS04340	COG3302	dmso reductase anchor subunit
YPTS_RS04345	COG3381	protein complex oligomerization
YPTS_RS04350	COG3038	cytochrome b561
YPTS_RS04355	COG3783	Cytochrome b(562)
YPTS_RS04365	COG1879	ABC-type sugar transport system periplasmic component
YPTS_RS04375	COG1129	ABC transporter
YPTS_RS04380	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS04385	COG3959	Transketolase, thiamine diphosphate binding domain
YPTS_RS04390	COG3958	Transketolase
YPTS_RS04395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPTS_RS04435	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPTS_RS04460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPTS_RS04465	COG1238	metal cluster binding
YPTS_RS04480	COG4536	flavin adenine dinucleotide binding
YPTS_RS04485	COG4137	Cytochrome C assembly protein
YPTS_RS04490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPTS_RS04515	COG3137	Salt-induced outer membrane protein
YPTS_RS04520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPTS_RS04525	COG3279	Response regulator of the LytR AlgR family
YPTS_RS04530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPTS_RS04535	COG1605	Chorismate mutase
YPTS_RS04535	COG0287	Prephenate dehydrogenase
YPTS_RS04550	COG0077	Prephenate dehydratase
YPTS_RS04550	COG1605	Chorismate mutase
YPTS_RS04555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPTS_RS04560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPTS_RS04565	COG0564	pseudouridine synthase activity
YPTS_RS04575	COG0542	response to heat
YPTS_RS04615	COG5544	Lipoprotein
YPTS_RS04620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPTS_RS04625	COG1042	CoA-binding domain protein
YPTS_RS04625	COG0045	succinate-CoA ligase (ADP-forming) activity
YPTS_RS04625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPTS_RS04630	COG3148	PFAM DTW domain containing protein
YPTS_RS04635	COG3118	belongs to the thioredoxin family
YPTS_RS04640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPTS_RS04645	COG2814	Major facilitator Superfamily
YPTS_RS04650	COG1566	PFAM secretion protein HlyD family protein
YPTS_RS04655	COG1846	Transcriptional regulator
YPTS_RS04665	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPTS_RS04670	COG2814	Major facilitator Superfamily
YPTS_RS04710	COG0765	amino acid transport
YPTS_RS04720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPTS_RS04735	COG0436	Aminotransferase
YPTS_RS04775	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPTS_RS04785	COG1960	acyl-CoA dehydrogenase activity
YPTS_RS04795	COG0121	glutamine amidotransferase
YPTS_RS04800	COG3034	peptidoglycan biosynthetic process
YPTS_RS04810	COG1805	sodium ion transport
YPTS_RS04815	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPTS_RS04835	COG1477	protein flavinylation
YPTS_RS04855	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPTS_RS04915	COG2226	methyltransferase
YPTS_RS04950	COG1940	carbohydrate kinase activity
YPTS_RS04955	COG0419	ATPase involved in DNA repair
YPTS_RS04960	COG0420	3'-5' exonuclease activity
YPTS_RS04970	COG0745	RESPONSE REGULATOR receiver
YPTS_RS04975	COG5002	protein histidine kinase activity
YPTS_RS04995	COG0366	Alpha amylase catalytic
YPTS_RS05015	COG0450	alkyl hydroperoxide reductase
YPTS_RS05035	COG1862	Preprotein translocase
YPTS_RS05040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPTS_RS05045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPTS_RS05065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPTS_RS05065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPTS_RS05080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPTS_RS05085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPTS_RS05095	COG0142	geranyltranstransferase activity
YPTS_RS05115	COG0693	protein deglycase activity
YPTS_RS05120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPTS_RS05130	COG2814	Major facilitator Superfamily
YPTS_RS05140	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPTS_RS05145	COG1845	cytochrome c oxidase, subunit III
YPTS_RS05150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPTS_RS05155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPTS_RS05165	COG2223	nitrite transmembrane transporter activity
YPTS_RS05170	COG3056	Lipoprotein
YPTS_RS05175	COG0271	Belongs to the BolA IbaG family
YPTS_RS05200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPTS_RS05205	COG0776	regulation of translation
YPTS_RS05210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPTS_RS05215	COG1555	photosystem II stabilization
YPTS_RS05220	COG0824	Thioesterase
YPTS_RS05230	COG4533	DNA binding
YPTS_RS05245	COG1522	sequence-specific DNA binding
YPTS_RS05250	COG1132	(ABC) transporter
YPTS_RS05255	COG1132	(ABC) transporter
YPTS_RS05260	COG0347	Belongs to the P(II) protein family
YPTS_RS05265	COG0004	ammonium transporteR
YPTS_RS05270	COG1946	Acyl-CoA thioesterase
YPTS_RS05275	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPTS_RS05280	COG3695	enzyme binding
YPTS_RS05300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPTS_RS05310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPTS_RS05315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_RS05320	COG1309	transcriptional regulator
YPTS_RS05325	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPTS_RS05330	COG1196	nuclear chromosome segregation
YPTS_RS05330	COG3264	Mechanosensitive ion channel
YPTS_RS05355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPTS_RS05405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_RS05430	COG0438	transferase activity, transferring glycosyl groups
YPTS_RS05445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_RS05445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YPTS_RS05470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPTS_RS05475	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPTS_RS05480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_RS05485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPTS_RS05485	COG4651	solute:proton antiporter activity
YPTS_RS05490	COG2223	nitrite transmembrane transporter activity
YPTS_RS05510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPTS_RS05515	COG3735	TraB family
YPTS_RS05520	COG2217	Heavy metal translocating P-type atpase
YPTS_RS05525	COG0789	Transcriptional regulator
YPTS_RS05530	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPTS_RS05535	COG0330	HflC and HflK could
YPTS_RS05540	COG3118	belongs to the thioredoxin family
YPTS_RS05545	COG0300	oxidoreductase activity
YPTS_RS05550	COG2755	lipolytic protein G-D-S-L family
YPTS_RS05555	COG4181	ATPase activity
YPTS_RS05560	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPTS_RS05565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPTS_RS05570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPTS_RS05580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPTS_RS05590	COG2501	S4 domain
YPTS_RS05635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPTS_RS05640	COG4589	Belongs to the CDS family
YPTS_RS05650	COG2267	carboxylic ester hydrolase activity
YPTS_RS05655	COG2453	phosphatase
YPTS_RS05655	COG0671	phosphoesterase, PA-phosphatase related
YPTS_RS05675	COG0667	Aldo Keto reductase
YPTS_RS05680	COG0656	L-ascorbic acid biosynthetic process
YPTS_RS05700	COG1472	Belongs to the glycosyl hydrolase 3 family
YPTS_RS05715	COG1187	pseudouridine synthase activity
YPTS_RS05720	COG2850	peptidyl-arginine hydroxylation
YPTS_RS05765	COG3423	Transcriptional regulator
YPTS_RS05770	COG4953	penicillin-binding protein 1C
YPTS_RS05775	COG2373	Large extracellular alpha-helical protein
YPTS_RS05790	COG3962	Belongs to the TPP enzyme family
YPTS_RS05795	COG0673	inositol 2-dehydrogenase activity
YPTS_RS05805	COG1129	ABC transporter
YPTS_RS05810	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS05815	COG0673	inositol 2-dehydrogenase activity
YPTS_RS05820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_RS05830	COG3718	enzyme involved in inositol metabolism
YPTS_RS05840	COG5265	(ABC) transporter
YPTS_RS05865	COG2197	response regulator
YPTS_RS05870	COG1278	Cold shock
YPTS_RS05890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPTS_RS05910	COG1686	Belongs to the peptidase S11 family
YPTS_RS05915	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPTS_RS05920	COG0772	Belongs to the SEDS family
YPTS_RS05925	COG0768	penicillin binding
YPTS_RS05935	COG0799	negative regulation of ribosome biogenesis
YPTS_RS05945	COG1466	dna polymerase III delta subunit
YPTS_RS05960	COG2888	peptidyl-tyrosine sulfation
YPTS_RS05965	COG1126	abc transporter atp-binding protein
YPTS_RS05970	COG0765	amino acid transport
YPTS_RS05975	COG0765	amino acid transport
YPTS_RS05985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPTS_RS05990	COG4535	Mg2 and Co2 transporter CorC
YPTS_RS06000	COG1702	phosphate starvation-inducible protein PhoH
YPTS_RS06010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPTS_RS06055	COG0367	asparagine synthase
YPTS_RS06060	COG0647	UMP catabolic process
YPTS_RS06065	COG1846	Transcriptional regulator
YPTS_RS06065	COG1940	carbohydrate kinase activity
YPTS_RS06070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPTS_RS06080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_RS06080	COG2190	(PTS) system
YPTS_RS06080	COG1263	PTS System
YPTS_RS06100	COG0735	belongs to the Fur family
YPTS_RS06120	COG0596	Alpha beta hydrolase
YPTS_RS06130	COG0582	viral genome integration into host DNA
YPTS_RS06135	COG2963	transposase activity
YPTS_RS06140	COG0582	viral genome integration into host DNA
YPTS_RS06170	COG2003	Belongs to the UPF0758 family
YPTS_RS06190	COG3596	GTP binding
YPTS_RS06195	COG4983	Phage plasmid primase, P4 family domain protein
YPTS_RS06230	COG0582	viral genome integration into host DNA
YPTS_RS06240	COG2867	negative regulation of translational initiation
YPTS_RS06250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPTS_RS06255	COG0497	DNA recombination
YPTS_RS06275	COG2009	succinate dehydrogenase
YPTS_RS06280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPTS_RS06285	COG1053	succinate dehydrogenase
YPTS_RS06295	COG0567	Dehydrogenase, E1 component
YPTS_RS06300	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPTS_RS06310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPTS_RS06315	COG1271	oxidase subunit
YPTS_RS06320	COG1294	oxidase, subunit
YPTS_RS06325	COG4890	Cyd operon protein YbgT
YPTS_RS06330	COG3790	cyd operon protein YbgE
YPTS_RS06335	COG0824	Thioesterase
YPTS_RS06340	COG0811	peptide transport
YPTS_RS06345	COG0848	biopolymer transport protein
YPTS_RS06350	COG3064	Membrane
YPTS_RS06350	COG3064	Membrane
YPTS_RS06360	COG2885	chlorophyll binding
YPTS_RS06365	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPTS_RS06410	COG1230	cation diffusion facilitator family transporter
YPTS_RS06415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPTS_RS06430	COG2017	converts alpha-aldose to the beta-anomer
YPTS_RS06440	COG1085	galactose-1-phosphate uridylyltransferase
YPTS_RS06445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPTS_RS06460	COG1119	ATPase activity
YPTS_RS06465	COG2005	Transcriptional regulator
YPTS_RS06465	COG3585	molybdate ion transport
YPTS_RS06475	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPTS_RS06480	COG4149	molybdate abc transporter
YPTS_RS06490	COG0561	phosphatase activity
YPTS_RS06515	COG2226	methyltransferase
YPTS_RS06525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YPTS_RS06535	COG4628	conserved protein (DUF2132)
YPTS_RS06540	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPTS_RS06550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPTS_RS06560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPTS_RS06565	COG0314	molybdopterin synthase activity
YPTS_RS06570	COG0670	Belongs to the BI1 family
YPTS_RS06590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPTS_RS06595	COG0583	DNA-binding transcription factor activity
YPTS_RS06605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPTS_RS06610	COG2211	Major facilitator Superfamily
YPTS_RS06630	COG1902	pentaerythritol trinitrate reductase activity
YPTS_RS06650	COG0842	Transport permease protein
YPTS_RS06655	COG0842	Transport permease protein
YPTS_RS06660	COG1131	(ABC) transporter
YPTS_RS06670	COG1309	transcriptional regulator
YPTS_RS06675	COG0513	Belongs to the DEAD box helicase family
YPTS_RS06700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPTS_RS06710	COG1686	Belongs to the peptidase S11 family
YPTS_RS06715	COG0277	FAD linked oxidase domain protein
YPTS_RS06735	COG2261	transglycosylase associated protein
YPTS_RS06745	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPTS_RS06760	COG4807	Protein conserved in bacteria
YPTS_RS06780	COG1122	ATPase activity
YPTS_RS06800	COG2897	thiosulfate sulfurtransferase activity
YPTS_RS06805	COG1732	Glycine betaine
YPTS_RS06810	COG1174	glycine betaine transport
YPTS_RS06815	COG1125	glycine betaine transport
YPTS_RS06820	COG1174	glycine betaine transport
YPTS_RS06825	COG0531	amino acid
YPTS_RS06830	COG1982	Orn Lys Arg decarboxylase major
YPTS_RS06840	COG0697	spore germination
YPTS_RS06865	COG0814	amino acid
YPTS_RS06880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPTS_RS06910	COG2205	protein histidine kinase activity
YPTS_RS06910	COG0784	Response regulator, receiver
YPTS_RS06920	COG0642	Histidine kinase
YPTS_RS06920	COG2198	Histidine kinase
YPTS_RS06925	COG2223	nitrite transmembrane transporter activity
YPTS_RS06945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPTS_RS06990	COG3395	kinase activity
YPTS_RS06995	COG0235	Class ii aldolase
YPTS_RS07000	COG1349	DNA-binding transcription factor activity
YPTS_RS07005	COG3622	Belongs to the hyi family
YPTS_RS07025	COG4386	tail sheath protein
YPTS_RS07070	COG3299	homolog of phage Mu protein gp47
YPTS_RS07090	COG1737	Transcriptional regulator
YPTS_RS07095	COG2723	6-phospho-beta-galactosidase activity
YPTS_RS07120	COG3157	Type VI secretion system effector, Hcp
YPTS_RS07140	COG3083	sulfuric ester hydrolase activity
YPTS_RS07145	COG3082	Protein of unknown function (DUF1414)
YPTS_RS07160	COG1061	Type III restriction enzyme res subunit
YPTS_RS07165	COG1187	pseudouridine synthase activity
YPTS_RS07170	COG2814	Major facilitator Superfamily
YPTS_RS07180	COG4172	Belongs to the ABC transporter superfamily
YPTS_RS07185	COG4239	(ABC) transporter, permease
YPTS_RS07190	COG4174	ABC transporter (Permease)
YPTS_RS07195	COG4166	transmembrane transport
YPTS_RS07200	COG2200	EAL domain
YPTS_RS07205	COG0791	NLP P60 protein
YPTS_RS07210	COG0671	phosphoesterase, PA-phosphatase related
YPTS_RS07215	COG0523	cobalamin synthesis protein
YPTS_RS07225	COG2186	Transcriptional regulator
YPTS_RS07230	COG0246	Mannitol dehydrogenase
YPTS_RS07255	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS07290	COG1129	ABC transporter
YPTS_RS07300	COG0494	nUDIX hydrolase
YPTS_RS07310	COG1105	Belongs to the carbohydrate kinase PfkB family
YPTS_RS07315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPTS_RS07315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPTS_RS07315	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPTS_RS07320	COG3710	Transcriptional regulator
YPTS_RS07335	COG3121	Chaperone
YPTS_RS07340	COG3188	usher protein
YPTS_RS07350	COG2855	membrane
YPTS_RS07355	COG0583	DNA-binding transcription factor activity
YPTS_RS07360	COG0833	amino acid
YPTS_RS07370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_RS07380	COG4771	TonB-dependent receptor
YPTS_RS07385	COG0625	glutathione transferase activity
YPTS_RS07410	COG2011	ABC-type metal ion transport system permease component
YPTS_RS07415	COG1686	Belongs to the peptidase S11 family
YPTS_RS07425	COG0814	amino acid
YPTS_RS07430	COG1349	DNA-binding transcription factor activity
YPTS_RS07440	COG0671	phosphoesterase, PA-phosphatase related
YPTS_RS07475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPTS_RS07480	COG3842	ATPase activity
YPTS_RS07485	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPTS_RS07490	COG1177	transmembrane transport
YPTS_RS07505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_RS07525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_RS07530	COG1120	ATPase activity
YPTS_RS07555	COG4160	amino acid transport
YPTS_RS07560	COG4215	(ABC) transporter
YPTS_RS07565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_RS07570	COG1126	abc transporter atp-binding protein
YPTS_RS07575	COG1605	Chorismate mutase
YPTS_RS07585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_RS07590	COG0702	epimerase
YPTS_RS07595	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPTS_RS07600	COG0028	Belongs to the TPP enzyme family
YPTS_RS07605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPTS_RS07615	COG2431	L-lysine efflux transmembrane transporter activity
YPTS_RS07620	COG3593	DNA synthesis involved in DNA repair
YPTS_RS07625	COG2990	Protein conserved in bacteria
YPTS_RS07630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_RS07640	COG1278	Cold shock
YPTS_RS07650	COG0542	response to heat
YPTS_RS07655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPTS_RS07665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPTS_RS07680	COG0492	ferredoxin-NADP+ reductase activity
YPTS_RS07690	COG1674	ftsk spoiiie
YPTS_RS07690	COG3107	peptidoglycan biosynthetic process
YPTS_RS07700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPTS_RS07715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPTS_RS07725	COG1882	Formate acetyltransferase
YPTS_RS07730	COG2116	formate transmembrane transporter activity
YPTS_RS07735	COG1944	ATP diphosphatase activity
YPTS_RS07740	COG0252	asparaginase activity
YPTS_RS07770	COG0539	negative regulation of cytoplasmic translation
YPTS_RS07780	COG2333	competence protein COMEC
YPTS_RS07780	COG0658	competence protein
YPTS_RS07795	COG5383	Protein conserved in bacteria
YPTS_RS07805	COG1278	Cold shock
YPTS_RS07820	COG3173	Aminoglycoside phosphotransferase
YPTS_RS07830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPTS_RS07850	COG2989	Protein conserved in bacteria
YPTS_RS07855	COG3108	Peptidase M15
YPTS_RS07860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPTS_RS07865	COG1448	Aminotransferase
YPTS_RS07885	COG0308	aminopeptidase N
YPTS_RS07890	COG3328	transposase activity
YPTS_RS07905	COG3217	Mosc domain protein beta barrel domain protein
YPTS_RS07905	COG0633	Ferredoxin
YPTS_RS07915	COG0488	(ABC) transporter
YPTS_RS07920	COG2995	paraquat-inducible protein a
YPTS_RS07925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPTS_RS07925	COG3008	intermembrane lipid transfer
YPTS_RS07930	COG3009	Protein conserved in bacteria
YPTS_RS07940	COG3130	regulation of translation
YPTS_RS07955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPTS_RS07970	COG1067	ATP-dependent peptidase activity
YPTS_RS07990	COG3070	regulator of competence-specific genes
YPTS_RS07995	COG1289	transmembrane transporter activity
YPTS_RS08000	COG3304	Inner membrane component domain
YPTS_RS08005	COG0210	DNA helicase
YPTS_RS08020	COG1832	CoA-binding protein
YPTS_RS08040	COG2920	part of a sulfur-relay system
YPTS_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS08085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPTS_RS08090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPTS_RS08095	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS08100	COG3425	synthase
YPTS_RS08110	COG1024	Enoyl-CoA hydratase
YPTS_RS08115	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS08125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPTS_RS08130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPTS_RS08265	COG0488	(ABC) transporter
YPTS_RS08280	COG0303	'Molybdopterin
YPTS_RS08290	COG1136	(ABC) transporter
YPTS_RS08320	COG0583	DNA-binding transcription factor activity
YPTS_RS08325	COG0477	Major facilitator Superfamily
YPTS_RS08335	COG2311	Membrane
YPTS_RS08350	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS08355	COG2949	membrane
YPTS_RS08370	COG1346	cytolysis
YPTS_RS08380	COG2814	Major facilitator Superfamily
YPTS_RS08405	COG0489	protein tyrosine kinase activity
YPTS_RS08420	COG2982	Protein involved in outer membrane biogenesis
YPTS_RS08425	COG1253	flavin adenine dinucleotide binding
YPTS_RS08430	COG4114	ferric iron reductase
YPTS_RS08435	COG0076	glutamate decarboxylase activity
YPTS_RS08440	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPTS_RS08455	COG1120	ATPase activity
YPTS_RS08460	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_RS08465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_RS08470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPTS_RS08485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPTS_RS08490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPTS_RS08500	COG0140	phosphoribosyl-ATP diphosphatase activity
YPTS_RS08500	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPTS_RS08540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_RS08560	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS08565	COG1129	ABC transporter
YPTS_RS08570	COG0371	Dehydrogenase
YPTS_RS08580	COG0531	amino acid
YPTS_RS08585	COG2925	Exonuclease
YPTS_RS08600	COG1470	cell adhesion involved in biofilm formation
YPTS_RS08600	COG1388	LysM domain
YPTS_RS08605	COG2271	Major facilitator Superfamily
YPTS_RS08610	COG3011	Protein conserved in bacteria
YPTS_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS08625	COG4948	Mandelate Racemase Muconate Lactonizing
YPTS_RS08640	COG0534	Mate efflux family protein
YPTS_RS08660	COG3122	Protein conserved in bacteria
YPTS_RS08710	COG4771	TonB-dependent receptor
YPTS_RS08715	COG1021	2,3-dihydroxybenzoate-AMP ligase
YPTS_RS08735	COG2226	methyltransferase
YPTS_RS08735	COG3433	isochorismatase activity
YPTS_RS08735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPTS_RS08750	COG1132	(ABC) transporter
YPTS_RS08755	COG2814	Major facilitator Superfamily
YPTS_RS08760	COG1169	isochorismate synthase
YPTS_RS08790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPTS_RS08810	COG2223	nitrite transmembrane transporter activity
YPTS_RS08845	COG1132	(ABC) transporter
YPTS_RS08855	COG2207	Transcriptional regulator
YPTS_RS08890	COG1113	amino acid transport
YPTS_RS08915	COG1496	oxidoreductase activity
YPTS_RS08920	COG2226	methyltransferase
YPTS_RS08930	COG3447	MASE1 domain protein
YPTS_RS08930	COG5002	protein histidine kinase activity
YPTS_RS08930	COG5001	Diguanylate cyclase
YPTS_RS08950	COG3716	PTS system mannose fructose sorbose family IID component
YPTS_RS08955	COG3715	PTS system
YPTS_RS08960	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_RS08960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_RS08965	COG1253	flavin adenine dinucleotide binding
YPTS_RS08970	COG1846	Transcriptional regulator
YPTS_RS08985	COG1012	belongs to the aldehyde dehydrogenase family
YPTS_RS08990	COG3384	dioxygenase
YPTS_RS09000	COG3971	2-oxopent-4-enoate hydratase activity
YPTS_RS09015	COG2368	4-hydroxyphenylacetate
YPTS_RS09020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPTS_RS09025	COG1760	l-serine dehydratase
YPTS_RS09050	COG0513	Belongs to the DEAD box helicase family
YPTS_RS09055	COG3141	response to X-ray
YPTS_RS09070	COG1770	oligopeptidase
YPTS_RS09085	COG1528	Iron-storage protein
YPTS_RS09090	COG2372	response to copper ion
YPTS_RS09115	COG3328	transposase activity
YPTS_RS09130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPTS_RS09135	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPTS_RS09155	COG3418	PFAM FlgN family protein
YPTS_RS09160	COG2747	anti-sigma28 factor FlgM
YPTS_RS09170	COG1815	bacterial-type flagellum-dependent cell motility
YPTS_RS09175	COG1558	bacterial-type flagellum-dependent cell motility
YPTS_RS09215	COG1256	bacterial-type flagellum assembly
YPTS_RS09225	COG2390	Transcriptional regulator
YPTS_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS09230	COG3347	Dehydrogenase
YPTS_RS09235	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS09245	COG1129	ABC transporter
YPTS_RS09250	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS09255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_RS09270	COG1987	bacterial-type flagellum assembly
YPTS_RS09295	COG1580	Controls the rotational direction of flagella during chemotaxis
YPTS_RS09310	COG1157	protein secretion by the type III secretion system
YPTS_RS09330	COG1677	Flagellar hook-basal body complex protein FliE
YPTS_RS09350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPTS_RS09355	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPTS_RS09390	COG1191	sigma factor activity
YPTS_RS09405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_RS09410	COG0765	amino acid transport
YPTS_RS09415	COG1126	abc transporter atp-binding protein
YPTS_RS09430	COG0506	proline dehydrogenase activity
YPTS_RS09430	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPTS_RS09430	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPTS_RS09445	COG0672	)-iron permease
YPTS_RS09450	COG2822	iron ion transport
YPTS_RS09470	COG1113	amino acid transport
YPTS_RS09490	COG3136	membrane protein required for alginate biosynthesis
YPTS_RS09500	COG2197	response regulator
YPTS_RS09670	COG4695	Portal protein
YPTS_RS09715	COG2176	DNA-directed DNA polymerase activity
YPTS_RS09715	COG5002	protein histidine kinase activity
YPTS_RS09855	COG2963	transposase activity
YPTS_RS09940	COG2188	Transcriptional regulator
YPTS_RS09950	COG0673	inositol 2-dehydrogenase activity
YPTS_RS09960	COG1175	transmembrane transport
YPTS_RS09965	COG0395	ABC-type sugar transport system, permease component
YPTS_RS09970	COG3842	ATPase activity
YPTS_RS09985	COG3121	Chaperone
YPTS_RS09995	COG3188	usher protein
YPTS_RS10010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_RS10010	COG2205	protein histidine kinase activity
YPTS_RS10020	COG0427	acetyl-CoA hydrolase
YPTS_RS10025	COG2030	dehydratase
YPTS_RS10050	COG2814	Major facilitator Superfamily
YPTS_RS10065	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPTS_RS10070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPTS_RS10080	COG1349	DNA-binding transcription factor activity
YPTS_RS10090	COG2066	Belongs to the glutaminase family
YPTS_RS10100	COG0672	)-iron permease
YPTS_RS10115	COG1136	(ABC) transporter
YPTS_RS10115	COG0577	efflux transmembrane transporter activity
YPTS_RS10125	COG1136	(ABC) transporter
YPTS_RS10125	COG0577	efflux transmembrane transporter activity
YPTS_RS10145	COG0006	proline dipeptidase activity
YPTS_RS10150	COG0457	Tetratricopeptide repeat
YPTS_RS10155	COG0726	polysaccharide deacetylase
YPTS_RS10155	COG1649	PFAM Uncharacterised BCR, COG1649
YPTS_RS10160	COG1215	transferase activity, transferring glycosyl groups
YPTS_RS10165	COG3658	cytochrome
YPTS_RS10180	COG1702	phosphate starvation-inducible protein PhoH
YPTS_RS10185	COG0387	Pfam Sodium calcium exchanger
YPTS_RS10190	COG3850	Histidine kinase
YPTS_RS10195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPTS_RS10245	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YPTS_RS10265	COG0402	S-adenosylhomocysteine deaminase activity
YPTS_RS10280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPTS_RS10285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_RS10350	COG0500	methyltransferase
YPTS_RS10390	COG5002	protein histidine kinase activity
YPTS_RS10420	COG0012	GTP binding
YPTS_RS10440	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPTS_RS10470	COG2890	protein-(glutamine-N5) methyltransferase activity
YPTS_RS10490	COG0659	secondary active sulfate transmembrane transporter activity
YPTS_RS10515	COG3833	ABC-type maltose transport systems, permease component
YPTS_RS10520	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPTS_RS10530	COG0584	glycerophosphoryl diester phosphodiesterase
YPTS_RS10535	COG1940	carbohydrate kinase activity
YPTS_RS10550	COG3381	protein complex oligomerization
YPTS_RS10565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPTS_RS10575	COG0673	inositol 2-dehydrogenase activity
YPTS_RS10580	COG0728	peptidoglycan biosynthetic process
YPTS_RS10600	COG3102	Protein conserved in bacteria
YPTS_RS10620	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPTS_RS10625	COG1801	Protein of unknown function DUF72
YPTS_RS10635	COG0494	nUDIX hydrolase
YPTS_RS10660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPTS_RS10670	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPTS_RS10675	COG0739	heme binding
YPTS_RS10680	COG1560	Kdo2-lipid A biosynthetic process
YPTS_RS10685	COG0469	pyruvate kinase activity
YPTS_RS10690	COG1737	Transcriptional regulator
YPTS_RS10695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPTS_RS10705	COG0800	Aldolase
YPTS_RS10720	COG0251	oxidation-reduction process
YPTS_RS10725	COG1199	ATP-dependent helicase activity
YPTS_RS10735	COG3065	identical protein binding
YPTS_RS10740	COG0318	PFAM AMP-dependent synthetase and ligase
YPTS_RS10745	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPTS_RS10750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPTS_RS10755	COG2894	cell division
YPTS_RS10770	COG2951	lytic endotransglycosylase activity
YPTS_RS10775	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPTS_RS10790	COG1104	cysteine desulfurase activity
YPTS_RS10820	COG2719	SpoVR family
YPTS_RS10830	COG2814	Major facilitator Superfamily
YPTS_RS10840	COG0583	DNA-binding transcription factor activity
YPTS_RS10855	COG2766	serine protein kinase
YPTS_RS10860	COG3713	MltA-interacting MipA family protein
YPTS_RS10880	COG3139	Protein of unknown function (DUF1315)
YPTS_RS10885	COG1335	isochorismatase
YPTS_RS10890	COG0252	asparaginase activity
YPTS_RS10895	COG0616	signal peptide processing
YPTS_RS10900	COG0778	Nitroreductase
YPTS_RS10910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPTS_RS10920	COG0494	nUDIX hydrolase
YPTS_RS10925	COG0708	Exodeoxyribonuclease III
YPTS_RS10930	COG0583	DNA-binding transcription factor activity
YPTS_RS10945	COG0788	formyltetrahydrofolate deformylase activity
YPTS_RS10955	COG0745	RESPONSE REGULATOR receiver
YPTS_RS10975	COG1454	alcohol dehydrogenase
YPTS_RS10975	COG1012	belongs to the aldehyde dehydrogenase family
YPTS_RS10980	COG2095	MarC family integral membrane protein
YPTS_RS10990	COG0601	transmembrane transport
YPTS_RS10995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPTS_RS11000	COG0444	Belongs to the ABC transporter superfamily
YPTS_RS11005	COG4608	Belongs to the ABC transporter superfamily
YPTS_RS11035	COG2350	Protein conserved in bacteria
YPTS_RS11040	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPTS_RS11070	COG3047	cAMP biosynthetic process
YPTS_RS11090	COG0134	indole-3-glycerol-phosphate synthase activity
YPTS_RS11090	COG0135	phosphoribosylanthranilate isomerase activity
YPTS_RS11100	COG0512	Glutamine amidotransferase of anthranilate synthase
YPTS_RS11125	COG0009	L-threonylcarbamoyladenylate synthase
YPTS_RS11130	COG1187	pseudouridine synthase activity
YPTS_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS11145	COG0616	signal peptide processing
YPTS_RS11165	COG0583	DNA-binding transcription factor activity
YPTS_RS11175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPTS_RS11185	COG0671	phosphoesterase, PA-phosphatase related
YPTS_RS11190	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPTS_RS11195	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPTS_RS11210	COG0023	Translation Initiation Factor
YPTS_RS11230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPTS_RS11235	COG2879	small protein
YPTS_RS11240	COG1966	Carbon starvation protein
YPTS_RS11250	COG2271	Major facilitator Superfamily
YPTS_RS11255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_RS11260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPTS_RS11270	COG4659	FMN binding
YPTS_RS11280	COG2207	Transcriptional regulator
YPTS_RS11280	COG3708	Transcriptional regulator
YPTS_RS11315	COG2274	protein secretion by the type I secretion system
YPTS_RS11330	COG1879	ABC-type sugar transport system periplasmic component
YPTS_RS11335	COG1129	ABC transporter
YPTS_RS11340	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS11350	COG0673	inositol 2-dehydrogenase activity
YPTS_RS11355	COG0385	Bile acid
YPTS_RS11375	COG1263	PTS System
YPTS_RS11375	COG2190	(PTS) system
YPTS_RS11375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_RS11380	COG2188	Transcriptional regulator
YPTS_RS11385	COG5339	Protein conserved in bacteria
YPTS_RS11395	COG0114	fumarate hydratase activity
YPTS_RS11405	COG2814	Major facilitator Superfamily
YPTS_RS11410	COG0583	DNA-binding transcription factor activity
YPTS_RS11415	COG1940	carbohydrate kinase activity
YPTS_RS11420	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPTS_RS11440	COG4221	oxidoreductase activity
YPTS_RS11445	COG3284	Transcriptional regulator
YPTS_RS11455	COG4221	oxidoreductase activity
YPTS_RS11460	COG3284	Transcriptional regulator
YPTS_RS11485	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPTS_RS11490	COG1757	Na H antiporter
YPTS_RS11495	COG1609	Transcriptional regulator
YPTS_RS11510	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS11515	COG1129	ABC transporter
YPTS_RS11530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPTS_RS11540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPTS_RS11565	COG0028	Belongs to the TPP enzyme family
YPTS_RS11570	COG0440	acetolactate synthase activity
YPTS_RS11575	COG1011	Hydrolase
YPTS_RS11595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPTS_RS11600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPTS_RS11605	COG0589	response to stress
YPTS_RS11610	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPTS_RS11615	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPTS_RS11630	COG0531	amino acid
YPTS_RS11640	COG0745	RESPONSE REGULATOR receiver
YPTS_RS11645	COG2205	protein histidine kinase activity
YPTS_RS11650	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPTS_RS11670	COG3038	cytochrome b561
YPTS_RS11685	COG3591	Belongs to the peptidase S1B family
YPTS_RS11700	COG1643	Atp-dependent helicase
YPTS_RS11710	COG2390	Transcriptional regulator
YPTS_RS11715	COG0246	Mannitol dehydrogenase
YPTS_RS11720	COG3784	Protein of unknown function (DUF1318)
YPTS_RS11730	COG2911	Protein conserved in bacteria
YPTS_RS11735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPTS_RS11740	COG3187	Heat shock protein
YPTS_RS11745	COG3042	response to heat
YPTS_RS11750	COG1285	pathogenesis
YPTS_RS11760	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPTS_RS11760	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPTS_RS11760	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPTS_RS11760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPTS_RS11770	COG0657	acetylesterase activity
YPTS_RS11790	COG4166	transmembrane transport
YPTS_RS11795	COG2866	Carboxypeptidase
YPTS_RS11800	COG4948	Mandelate Racemase Muconate Lactonizing
YPTS_RS11805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPTS_RS11815	COG5642	Protein of unknown function (DUF2384)
YPTS_RS11820	COG5654	RES domain protein
YPTS_RS11830	COG3106	COG3106 Predicted ATPase
YPTS_RS11840	COG1983	PspC domain protein
YPTS_RS11850	COG1842	Phage shock protein A
YPTS_RS11855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPTS_RS11865	COG4166	transmembrane transport
YPTS_RS11870	COG4168	peptide transport system, permease
YPTS_RS11875	COG4171	peptide transport system, permease
YPTS_RS11885	COG4172	Belongs to the ABC transporter superfamily
YPTS_RS11890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPTS_RS11890	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPTS_RS11895	COG3104	oligopeptide transport
YPTS_RS11910	COG0625	glutathione transferase activity
YPTS_RS11930	COG4989	oxidoreductase activity
YPTS_RS11935	COG3313	Fe-S protein
YPTS_RS11940	COG2194	sulfuric ester hydrolase activity
YPTS_RS11945	COG1309	transcriptional regulator
YPTS_RS11950	COG1902	pentaerythritol trinitrate reductase activity
YPTS_RS11960	COG0346	lactoylglutathione lyase activity
YPTS_RS11970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPTS_RS11980	COG0791	NLP P60 protein
YPTS_RS11995	COG0583	DNA-binding transcription factor activity
YPTS_RS12000	COG2814	Major facilitator Superfamily
YPTS_RS12005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPTS_RS12010	COG0307	riboflavin synthase, alpha
YPTS_RS12045	COG1388	LysM domain
YPTS_RS12045	COG1376	ErfK ybiS ycfS ynhG family protein
YPTS_RS12060	COG0719	Fe-S assembly protein
YPTS_RS12065	COG0396	ATPase activity
YPTS_RS12070	COG0719	Fe-S assembly protein
YPTS_RS12075	COG0316	Belongs to the HesB IscA family
YPTS_RS12085	COG2050	protein possibly involved in aromatic compounds catabolism
YPTS_RS12090	COG0277	FAD linked oxidase domain protein
YPTS_RS12090	COG0247	lactate metabolic process
YPTS_RS12095	COG0628	permease
YPTS_RS12100	COG0574	Belongs to the PEP-utilizing enzyme family
YPTS_RS12100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPTS_RS12125	COG0791	NLP P60 protein
YPTS_RS12170	COG0386	Belongs to the glutathione peroxidase family
YPTS_RS12185	COG0776	regulation of translation
YPTS_RS12220	COG4249	Peptidase C14 caspase catalytic subunit p20
YPTS_RS12245	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPTS_RS12250	COG1121	(ABC) transporter
YPTS_RS12255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPTS_RS12260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPTS_RS12270	COG3001	Fructosamine kinase
YPTS_RS12280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPTS_RS12285	COG1917	Cupin 2, conserved barrel domain protein
YPTS_RS12295	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS12305	COG1175	transmembrane transport
YPTS_RS12310	COG0395	ABC-type sugar transport system, permease component
YPTS_RS12315	COG3842	ATPase activity
YPTS_RS12320	COG1653	transport
YPTS_RS12325	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPTS_RS12330	COG1988	membrane-bound metal-dependent
YPTS_RS12335	COG1823	symporter activity
YPTS_RS12340	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPTS_RS12350	COG0823	Involved in the tonB-independent uptake of proteins
YPTS_RS12355	COG2814	Major facilitator Superfamily
YPTS_RS12360	COG3121	Chaperone
YPTS_RS12375	COG3121	Chaperone
YPTS_RS12380	COG3539	Fimbrial protein
YPTS_RS12390	COG0793	Belongs to the peptidase S41A family
YPTS_RS12400	COG1956	GAF domain-containing protein
YPTS_RS12405	COG2995	paraquat-inducible protein a
YPTS_RS12410	COG3008	intermembrane lipid transfer
YPTS_RS12430	COG3121	Chaperone
YPTS_RS12475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPTS_RS12485	COG5295	Hep Hag repeat protein
YPTS_RS12485	COG5295	Hep Hag repeat protein
YPTS_RS12490	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPTS_RS12500	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPTS_RS12505	COG0745	RESPONSE REGULATOR receiver
YPTS_RS12515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPTS_RS12520	COG0840	transmembrane signaling receptor activity
YPTS_RS12525	COG0840	transmembrane signaling receptor activity
YPTS_RS12540	COG0835	chemotaxis
YPTS_RS12545	COG2198	Histidine kinase
YPTS_RS12545	COG0643	Histidine kinase
YPTS_RS12550	COG1360	Flagellar Motor Protein
YPTS_RS12575	COG1285	pathogenesis
YPTS_RS12585	COG0840	transmembrane signaling receptor activity
YPTS_RS12605	COG0604	alcohol dehydrogenase
YPTS_RS12605	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS12605	COG3321	synthase
YPTS_RS12615	COG1522	sequence-specific DNA binding
YPTS_RS12640	COG1733	regulation of RNA biosynthetic process
YPTS_RS12645	COG0702	epimerase
YPTS_RS12650	COG0840	transmembrane signaling receptor activity
YPTS_RS12665	COG0538	isocitrate dehydrogenase activity
YPTS_RS12670	COG1187	pseudouridine synthase activity
YPTS_RS12690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPTS_RS12700	COG0745	RESPONSE REGULATOR receiver
YPTS_RS12710	COG2850	peptidyl-arginine hydroxylation
YPTS_RS12730	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPTS_RS12740	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPTS_RS12745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPTS_RS12750	COG3134	Outer membrane lipoprotein
YPTS_RS12765	COG1252	NADH dehydrogenase
YPTS_RS12790	COG5633	Lipoprotein
YPTS_RS12795	COG0537	adenosine 5'-monophosphoramidase activity
YPTS_RS12800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPTS_RS12835	COG4695	Portal protein
YPTS_RS12850	COG1263	PTS System
YPTS_RS12850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_RS12855	COG0084	hydrolase, TatD family'
YPTS_RS12860	COG0470	DNA polymerase III
YPTS_RS12870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPTS_RS12875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPTS_RS12880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPTS_RS12910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPTS_RS12915	COG1399	metal-binding, possibly nucleic acid-binding protein
YPTS_RS12925	COG0564	pseudouridine synthase activity
YPTS_RS12930	COG1530	ribonuclease E activity
YPTS_RS12935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPTS_RS12970	COG3328	transposase activity
YPTS_RS12975	COG2197	response regulator
YPTS_RS12980	COG0628	permease
YPTS_RS13005	COG1560	Kdo2-lipid A biosynthetic process
YPTS_RS13015	COG5645	(Lipo)protein
YPTS_RS13020	COG2943	transferase activity, transferring hexosyl groups
YPTS_RS13025	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YPTS_RS13050	COG3916	Acyl-homoserine-lactone synthase
YPTS_RS13055	COG2771	luxR family
YPTS_RS13060	COG0583	DNA-binding transcription factor activity
YPTS_RS13070	COG0477	Major facilitator Superfamily
YPTS_RS13080	COG0667	Aldo Keto reductase
YPTS_RS13105	COG1203	CRISPR-associated helicase, Cas3
YPTS_RS13110	COG1518	maintenance of DNA repeat elements
YPTS_RS13115	COG0668	transmembrane transport
YPTS_RS13135	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPTS_RS13140	COG0395	ABC-type sugar transport system, permease component
YPTS_RS13155	COG1609	Transcriptional regulator
YPTS_RS13165	COG3842	ATPase activity
YPTS_RS13180	COG3210	domain, Protein
YPTS_RS13200	COG3210	domain, Protein
YPTS_RS13205	COG2831	hemolysin activation secretion protein
YPTS_RS13210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPTS_RS13215	COG4638	Rieske (2fe-2S)
YPTS_RS13220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPTS_RS13225	COG0473	3-isopropylmalate dehydrogenase activity
YPTS_RS13230	COG0583	DNA-binding transcription factor activity
YPTS_RS13235	COG1609	Transcriptional regulator
YPTS_RS13240	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS13245	COG1129	ABC transporter
YPTS_RS13250	COG1879	ABC-type sugar transport system periplasmic component
YPTS_RS13255	COG1063	alcohol dehydrogenase
YPTS_RS13275	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPTS_RS13310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_RS13315	COG0765	amino acid transport
YPTS_RS13320	COG1126	abc transporter atp-binding protein
YPTS_RS13340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPTS_RS13355	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPTS_RS13370	COG1169	isochorismate synthase
YPTS_RS13380	COG4575	ribosome binding
YPTS_RS13395	COG0129	dihydroxy-acid dehydratase activity
YPTS_RS13410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPTS_RS13420	COG1609	Transcriptional regulator
YPTS_RS13425	COG1649	PFAM Uncharacterised BCR, COG1649
YPTS_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS13435	COG3265	gluconokinase activity
YPTS_RS13440	COG2731	YhcH YjgK YiaL family protein
YPTS_RS13455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPTS_RS13460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPTS_RS13470	COG0839	Belongs to the complex I subunit 6 family
YPTS_RS13485	COG1034	ATP synthesis coupled electron transport
YPTS_RS13505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPTS_RS13515	COG0583	DNA-binding transcription factor activity
YPTS_RS13525	COG0436	Aminotransferase
YPTS_RS13540	COG0471	metal ion transport
YPTS_RS13540	COG0490	domain, Protein
YPTS_RS13545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPTS_RS13570	COG0857	belongs to the CobB CobQ family
YPTS_RS13570	COG0280	phosphate acetyltransferase
YPTS_RS13575	COG1609	Transcriptional regulator
YPTS_RS13590	COG3037	sugar-specific permease SgaT UlaA
YPTS_RS13595	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPTS_RS13600	COG0622	Phosphoesterase
YPTS_RS13610	COG1090	epimerase
YPTS_RS13615	COG4598	ABC transporter
YPTS_RS13620	COG4160	amino acid transport
YPTS_RS13625	COG4215	(ABC) transporter
YPTS_RS13630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_RS13640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPTS_RS13645	COG1286	toxin biosynthetic process
YPTS_RS13650	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPTS_RS13655	COG0285	dihydrofolate synthase activity
YPTS_RS13665	COG0586	Pfam SNARE associated Golgi protein
YPTS_RS13675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPTS_RS13695	COG0697	spore germination
YPTS_RS13710	COG1794	racemase activity, acting on amino acids and derivatives
YPTS_RS13715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPTS_RS13730	COG3101	peptidyl-lysine hydroxylation
YPTS_RS13735	COG0730	response to heat
YPTS_RS13750	COG2890	protein-(glutamine-N5) methyltransferase activity
YPTS_RS13760	COG2062	phosphohistidine phosphatase, SixA
YPTS_RS13775	COG3691	Protein conserved in bacteria
YPTS_RS13790	COG4235	cytochrome complex assembly
YPTS_RS13790	COG3088	subunit of a heme lyase
YPTS_RS13795	COG4235	cytochrome complex assembly
YPTS_RS13795	COG3088	subunit of a heme lyase
YPTS_RS13800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPTS_RS13805	COG1138	Cytochrome C-type biogenesis protein
YPTS_RS13815	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPTS_RS13820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPTS_RS13825	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPTS_RS13845	COG1704	LemA family
YPTS_RS13855	COG2824	Alkylphosphonate utilization operon protein PhnA
YPTS_RS13935	COG3188	usher protein
YPTS_RS13940	COG3121	Chaperone
YPTS_RS14000	COG2951	lytic endotransglycosylase activity
YPTS_RS14035	COG0243	molybdopterin cofactor binding
YPTS_RS14040	COG0437	4 iron, 4 sulfur cluster binding
YPTS_RS14045	COG3302	dmso reductase anchor subunit
YPTS_RS14050	COG3381	protein complex oligomerization
YPTS_RS14080	COG3038	cytochrome b561
YPTS_RS14085	COG0436	Aminotransferase
YPTS_RS14110	COG0667	Aldo Keto reductase
YPTS_RS14125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPTS_RS14175	COG3530	Putative quorum-sensing-regulated virulence factor
YPTS_RS14190	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPTS_RS14200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_RS14215	COG2205	protein histidine kinase activity
YPTS_RS14220	COG0745	RESPONSE REGULATOR receiver
YPTS_RS14225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_RS14240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPTS_RS14255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPTS_RS14265	COG3850	Histidine kinase
YPTS_RS14265	COG5002	protein histidine kinase activity
YPTS_RS14270	COG0745	RESPONSE REGULATOR receiver
YPTS_RS14280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YPTS_RS14290	COG4208	sulfate ABC transporter
YPTS_RS14295	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPTS_RS14300	COG4150	thiosulfate binding
YPTS_RS14310	COG1737	Transcriptional regulator
YPTS_RS14320	COG2731	YhcH YjgK YiaL family protein
YPTS_RS14330	COG4886	Leucine-rich repeat (LRR) protein
YPTS_RS14340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPTS_RS14345	COG2837	iron assimilation
YPTS_RS14355	COG3111	PFAM Bacterial OB fold (BOF) protein
YPTS_RS14375	COG0456	acetyltransferase
YPTS_RS14425	COG3005	denitrification pathway
YPTS_RS14430	COG3043	anaerobic respiration
YPTS_RS14440	COG3062	negative regulation of establishment of protein localization
YPTS_RS14445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_RS14445	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_RS14450	COG2197	response regulator
YPTS_RS14460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPTS_RS14470	COG1988	membrane-bound metal-dependent
YPTS_RS14475	COG0641	radical SAM
YPTS_RS14480	COG3119	arylsulfatase activity
YPTS_RS14485	COG3842	ATPase activity
YPTS_RS14490	COG1175	transmembrane transport
YPTS_RS14505	COG1393	Belongs to the ArsC family
YPTS_RS14515	COG1876	peptidase activity
YPTS_RS14535	COG2321	neutral zinc metallopeptidase
YPTS_RS14545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPTS_RS14555	COG2716	regulation of RNA biosynthetic process
YPTS_RS14560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPTS_RS14580	COG0628	permease
YPTS_RS14585	COG4783	chaperone-mediated protein folding
YPTS_RS14590	COG1393	Belongs to the ArsC family
YPTS_RS14600	COG2233	PERMEase
YPTS_RS14615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPTS_RS14620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPTS_RS14635	COG0581	inorganic phosphate transmembrane transporter activity
YPTS_RS14645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPTS_RS14660	COG2239	Acts as a magnesium transporter
YPTS_RS14665	COG0443	Heat shock 70 kDa protein
YPTS_RS14670	COG1177	transmembrane transport
YPTS_RS14675	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPTS_RS14685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPTS_RS14695	COG3842	ATPase activity
YPTS_RS14720	COG2205	protein histidine kinase activity
YPTS_RS14725	COG0745	RESPONSE REGULATOR receiver
YPTS_RS14730	COG3422	double-strand break repair
YPTS_RS14735	COG0826	peptidase U32
YPTS_RS14810	COG0517	IMP dehydrogenase activity
YPTS_RS14810	COG0516	GMP reductase activity
YPTS_RS14820	COG1645	bacterial-type flagellum-dependent swarming motility
YPTS_RS14835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPTS_RS14840	COG2976	Protein conserved in bacteria
YPTS_RS14890	COG3468	outer membrane autotransporter barrel domain protein
YPTS_RS14895	COG3468	outer membrane autotransporter barrel domain protein
YPTS_RS14910	COG2975	iron-sulfur cluster assembly
YPTS_RS14915	COG0633	Ferredoxin
YPTS_RS14935	COG0822	iron-sulfur transferase activity
YPTS_RS14940	COG1104	cysteine desulfurase activity
YPTS_RS14960	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPTS_RS14965	COG3683	transport system, periplasmic component
YPTS_RS14970	COG3711	transcriptional antiterminator
YPTS_RS14975	COG2814	Major facilitator Superfamily
YPTS_RS14995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPTS_RS14995	COG1017	nitric oxide dioxygenase activity
YPTS_RS15000	COG2188	Transcriptional regulator
YPTS_RS15005	COG0347	Belongs to the P(II) protein family
YPTS_RS15010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPTS_RS15010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPTS_RS15015	COG2204	response regulator
YPTS_RS15020	COG3170	Tfp pilus assembly protein FimV
YPTS_RS15025	COG2205	protein histidine kinase activity
YPTS_RS15055	COG0560	Phosphoserine phosphatase
YPTS_RS15065	COG1737	Transcriptional regulator
YPTS_RS15070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_RS15115	COG3086	response to oxidative stress
YPTS_RS15120	COG3026	antisigma factor binding
YPTS_RS15135	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPTS_RS15145	COG0513	Belongs to the DEAD box helicase family
YPTS_RS15195	COG1984	allophanate hydrolase subunit 2
YPTS_RS15200	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YPTS_RS15205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPTS_RS15210	COG5212	phosphodiesterase
YPTS_RS15220	COG3272	Protein of unknown function (DUF1722)
YPTS_RS15250	COG2205	protein histidine kinase activity
YPTS_RS15255	COG0745	RESPONSE REGULATOR receiver
YPTS_RS15275	COG0033	Phosphoglucomutase
YPTS_RS15280	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPTS_RS15300	COG1917	Cupin 2, conserved barrel domain protein
YPTS_RS15300	COG2169	Transcriptional regulator
YPTS_RS15305	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPTS_RS15310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPTS_RS15315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPTS_RS15335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPTS_RS15350	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPTS_RS15355	COG4413	Urea transporter
YPTS_RS15365	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPTS_RS15390	COG0831	urea catabolic process
YPTS_RS15395	COG1124	(ABC) transporter
YPTS_RS15400	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPTS_RS15405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPTS_RS15415	COG0747	negative chemotaxis
YPTS_RS15420	COG1278	Cold shock
YPTS_RS15460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPTS_RS15465	COG4175	Glycine betaine
YPTS_RS15470	COG4176	ABC-type proline glycine betaine transport system permease component
YPTS_RS15475	COG2113	Glycine betaine
YPTS_RS15485	COG1953	Uracil, thiamine, allantoin
YPTS_RS15505	COG2226	methyltransferase
YPTS_RS15515	COG1388	LysM domain
YPTS_RS15515	COG0741	lytic transglycosylase activity
YPTS_RS15530	COG0656	L-ascorbic acid biosynthetic process
YPTS_RS15565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPTS_RS15575	COG2011	ABC-type metal ion transport system permease component
YPTS_RS15580	COG1464	Belongs to the NlpA lipoprotein family
YPTS_RS15590	COG1720	tRNA m6t6A37 methyltransferase activity
YPTS_RS15600	COG3015	lipoprotein NlpE involved in copper resistance
YPTS_RS15610	COG4681	YaeQ
YPTS_RS15620	COG4568	rho-dependent transcription termination
YPTS_RS15635	COG0346	lactoylglutathione lyase activity
YPTS_RS15645	COG0587	DNA-directed DNA polymerase activity
YPTS_RS15670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPTS_RS15685	COG0750	zinc metalloprotease
YPTS_RS15690	COG0575	Belongs to the CDS family
YPTS_RS15750	COG0564	pseudouridine synthase activity
YPTS_RS15755	COG3098	single-species biofilm formation
YPTS_RS15775	COG1611	Belongs to the LOG family
YPTS_RS15790	COG2363	Small membrane protein
YPTS_RS15795	COG0583	DNA-binding transcription factor activity
YPTS_RS15800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPTS_RS15805	COG2166	iron-sulfur cluster assembly
YPTS_RS15810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPTS_RS15815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPTS_RS15835	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPTS_RS15845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPTS_RS15850	COG1074	ATP-dependent DNA helicase activity
YPTS_RS15860	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPTS_RS15925	COG0667	Aldo Keto reductase
YPTS_RS15955	COG1609	Transcriptional regulator
YPTS_RS15965	COG0583	DNA-binding transcription factor activity
YPTS_RS15970	COG2814	Major facilitator Superfamily
YPTS_RS15990	COG0840	transmembrane signaling receptor activity
YPTS_RS16055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPTS_RS16075	COG0288	reversible hydration of carbon dioxide
YPTS_RS16105	COG3119	arylsulfatase activity
YPTS_RS16110	COG1349	DNA-binding transcription factor activity
YPTS_RS16120	COG2222	sugar isomerase
YPTS_RS16125	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_RS16130	COG3715	PTS system
YPTS_RS16135	COG3716	PTS system mannose fructose sorbose family IID component
YPTS_RS16140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_RS16150	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_RS16160	COG0641	radical SAM
YPTS_RS16165	COG3119	arylsulfatase activity
YPTS_RS16195	COG2271	Major facilitator Superfamily
YPTS_RS16215	COG1263	PTS System
YPTS_RS16215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_RS16220	COG1874	Beta-galactosidase
YPTS_RS16225	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPTS_RS16230	COG3833	ABC-type maltose transport systems, permease component
YPTS_RS16235	COG1175	transmembrane transport
YPTS_RS16240	COG2182	Extracellular solute-binding protein
YPTS_RS16250	COG1129	ABC transporter
YPTS_RS16255	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS16260	COG1879	ABC-type sugar transport system periplasmic component
YPTS_RS16270	COG0791	NLP P60 protein
YPTS_RS16275	COG1695	Transcriptional regulator
YPTS_RS16370	COG2944	sequence-specific DNA binding
YPTS_RS16400	COG4974	Belongs to the 'phage' integrase family
YPTS_RS16475	COG4695	Portal protein
YPTS_RS16605	COG0582	viral genome integration into host DNA
YPTS_RS16625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPTS_RS16630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPTS_RS16635	COG4974	Belongs to the 'phage' integrase family
YPTS_RS16640	COG0716	FMN binding
YPTS_RS16645	COG4452	Inner membrane protein CreD
YPTS_RS16650	COG2205	protein histidine kinase activity
YPTS_RS16655	COG0745	RESPONSE REGULATOR receiver
YPTS_RS16680	COG1272	protein, Hemolysin III
YPTS_RS16690	COG5295	Hep Hag repeat protein
YPTS_RS16720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPTS_RS16725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPTS_RS16730	COG0006	proline dipeptidase activity
YPTS_RS16745	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPTS_RS16750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPTS_RS16785	COG0191	fructose-bisphosphate aldolase activity
YPTS_RS16800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPTS_RS16805	COG0501	Belongs to the peptidase M48B family
YPTS_RS16815	COG1166	arginine decarboxylase activity
YPTS_RS16830	COG2356	endonuclease I
YPTS_RS16840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPTS_RS16845	COG0189	ligase activity
YPTS_RS16860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPTS_RS16870	COG2805	Type II/IV secretion system protein
YPTS_RS16875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPTS_RS16880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPTS_RS16885	COG0762	integral membrane protein
YPTS_RS16895	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPTS_RS16900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPTS_RS16905	COG1073	alpha beta
YPTS_RS16905	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPTS_RS16905	COG3064	Membrane
YPTS_RS16920	COG3171	Protein conserved in bacteria
YPTS_RS16930	COG1194	a g-specific adenine glycosylase
YPTS_RS16950	COG4774	siderophore transport
YPTS_RS16955	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS16960	COG1129	ABC transporter
YPTS_RS16965	COG1879	ABC-type sugar transport system periplasmic component
YPTS_RS16970	COG1982	Orn Lys Arg decarboxylase major
YPTS_RS17105	COG3916	Acyl-homoserine-lactone synthase
YPTS_RS17110	COG2771	luxR family
YPTS_RS17155	COG2211	Major facilitator Superfamily
YPTS_RS17165	COG1609	Transcriptional regulator
YPTS_RS17170	COG0471	metal ion transport
YPTS_RS17200	COG3209	COG3209 Rhs family protein
YPTS_RS17225	COG3209	COG3209 Rhs family protein
YPTS_RS17235	COG3501	Rhs element vgr protein
YPTS_RS17250	COG2610	gluconate transmembrane transporter activity
YPTS_RS17265	COG1132	(ABC) transporter
YPTS_RS17270	COG1132	(ABC) transporter
YPTS_RS17270	COG2375	cellular response to nickel ion
YPTS_RS17295	COG3433	isochorismatase activity
YPTS_RS17295	COG2226	methyltransferase
YPTS_RS17295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPTS_RS17305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPTS_RS17305	COG2226	methyltransferase
YPTS_RS17305	COG3433	isochorismatase activity
YPTS_RS17315	COG4771	TonB-dependent receptor
YPTS_RS17320	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPTS_RS17325	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPTS_RS17355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_RS17360	COG5001	Diguanylate cyclase
YPTS_RS17370	COG2801	Transposase and inactivated derivatives
YPTS_RS17380	COG3133	Outer membrane lipoprotein
YPTS_RS17410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YPTS_RS17415	COG1191	sigma factor activity
YPTS_RS17440	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YPTS_RS17445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YPTS_RS17450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YPTS_RS17455	COG3710	Transcriptional regulator
YPTS_RS17475	COG1256	bacterial-type flagellum assembly
YPTS_RS17495	COG4786	Flagellar basal body rod
YPTS_RS17500	COG4787	bacterial-type flagellum-dependent cell motility
YPTS_RS17505	COG1749	Flagellar hook protein flgE
YPTS_RS17510	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPTS_RS17515	COG1558	bacterial-type flagellum-dependent cell motility
YPTS_RS17520	COG1815	bacterial-type flagellum-dependent cell motility
YPTS_RS17525	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPTS_RS17590	COG1987	bacterial-type flagellum assembly
YPTS_RS17595	COG1684	flagellar biosynthetic protein fliR
YPTS_RS17600	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPTS_RS17620	COG4592	Periplasmic binding protein
YPTS_RS17645	COG3469	chitinase activity
YPTS_RS17650	COG3397	chitin binding
YPTS_RS17685	COG4964	Belongs to the GSP D family
YPTS_RS17735	COG0848	biopolymer transport protein
YPTS_RS17740	COG0811	peptide transport
YPTS_RS17745	COG0626	cystathionine gamma-synthase activity
YPTS_RS17750	COG0586	Pfam SNARE associated Golgi protein
YPTS_RS17755	COG2207	Transcriptional regulator
YPTS_RS17760	COG1979	alcohol dehydrogenase
YPTS_RS17770	COG0656	L-ascorbic acid biosynthetic process
YPTS_RS17780	COG2132	Multicopper oxidase
YPTS_RS17790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPTS_RS17795	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPTS_RS17800	COG0583	DNA-binding transcription factor activity
YPTS_RS17810	COG3150	esterase
YPTS_RS17815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPTS_RS17820	COG3151	Protein conserved in bacteria
YPTS_RS17825	COG0494	nUDIX hydrolase
YPTS_RS17830	COG1538	Outer membrane efflux protein
YPTS_RS17845	COG0754	glutathionylspermidine amidase activity
YPTS_RS17850	COG3384	dioxygenase
YPTS_RS17870	COG0531	amino acid
YPTS_RS17885	COG3025	triphosphatase activity
YPTS_RS17890	COG4991	sh3 domain protein
YPTS_RS17905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPTS_RS17920	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YPTS_RS17925	COG0358	DNA primase activity
YPTS_RS17970	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPTS_RS18065	COG4695	Portal protein
YPTS_RS18120	COG4974	Belongs to the 'phage' integrase family
YPTS_RS18195	COG0251	oxidation-reduction process
YPTS_RS18215	COG0436	Aminotransferase
YPTS_RS18240	COG1289	transmembrane transporter activity
YPTS_RS18260	COG0395	ABC-type sugar transport system, permease component
YPTS_RS18270	COG2182	Extracellular solute-binding protein
YPTS_RS18275	COG1609	Transcriptional regulator
YPTS_RS18280	COG3459	Glycosyltransferase 36 associated
YPTS_RS18285	COG3842	ATPase activity
YPTS_RS18305	COG3210	domain, Protein
YPTS_RS18360	COG3210	domain, Protein
YPTS_RS18370	COG3210	domain, Protein
YPTS_RS18375	COG2831	hemolysin activation secretion protein
YPTS_RS18380	COG4245	von Willebrand factor, type A
YPTS_RS18390	COG4245	von Willebrand factor, type A
YPTS_RS18395	COG4245	von Willebrand factor, type A
YPTS_RS18415	COG3247	response to pH
YPTS_RS18420	COG1902	pentaerythritol trinitrate reductase activity
YPTS_RS18420	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPTS_RS18435	COG1451	nucleotide metabolic process
YPTS_RS18440	COG0673	inositol 2-dehydrogenase activity
YPTS_RS18455	COG2721	sulfolactate sulfo-lyase activity
YPTS_RS18475	COG2271	Major facilitator Superfamily
YPTS_RS18490	COG0586	Pfam SNARE associated Golgi protein
YPTS_RS18510	COG4575	ribosome binding
YPTS_RS18515	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPTS_RS18525	COG2259	Doxx family
YPTS_RS18530	COG0435	Glutathione S-transferase
YPTS_RS18535	COG0583	DNA-binding transcription factor activity
YPTS_RS18540	COG1741	Belongs to the pirin family
YPTS_RS18545	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPTS_RS18565	COG2823	Periplasmic or secreted lipoprotein
YPTS_RS18575	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPTS_RS18585	COG2198	Histidine kinase
YPTS_RS18585	COG0784	Response regulator, receiver
YPTS_RS18585	COG5002	protein histidine kinase activity
YPTS_RS18595	COG1242	4 iron, 4 sulfur cluster binding
YPTS_RS18600	COG0069	glutamate synthase activity
YPTS_RS18600	COG0067	glutamate synthase
YPTS_RS18600	COG0070	glutamate synthase
YPTS_RS18605	COG0493	'glutamate synthase
YPTS_RS18615	COG2969	positive regulation of protein catabolic process
YPTS_RS18620	COG0625	glutathione transferase activity
YPTS_RS18640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPTS_RS18645	COG3105	Protein conserved in bacteria
YPTS_RS18650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPTS_RS18655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPTS_RS18665	COG5007	Belongs to the BolA IbaG family
YPTS_RS18670	COG3113	response to antibiotic
YPTS_RS18675	COG2854	intermembrane phospholipid transfer
YPTS_RS18680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPTS_RS18685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPTS_RS18690	COG1127	ABC transporter
YPTS_RS18695	COG0530	calcium, potassium:sodium antiporter activity
YPTS_RS18700	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPTS_RS18700	COG0517	IMP dehydrogenase activity
YPTS_RS18705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPTS_RS18710	COG3117	lipopolysaccharide transmembrane transporter activity
YPTS_RS18715	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPTS_RS18720	COG1137	ATPase activity
YPTS_RS18725	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPTS_RS18745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_RS18770	COG1609	Transcriptional regulator
YPTS_RS18775	COG1263	PTS System
YPTS_RS18775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_RS18780	COG0366	Alpha amylase catalytic
YPTS_RS18785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPTS_RS18790	COG3783	Cytochrome b(562)
YPTS_RS18800	COG0312	modulator of DNA gyrase
YPTS_RS18810	COG2732	(Barnase) inhibitor
YPTS_RS18840	COG0583	DNA-binding transcription factor activity
YPTS_RS18885	COG0312	modulator of DNA gyrase
YPTS_RS18890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPTS_RS18895	COG3164	Protein of unknown function
YPTS_RS18900	COG1530	ribonuclease E activity
YPTS_RS18905	COG0424	maF-like protein
YPTS_RS18910	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPTS_RS18915	COG1792	Involved in formation and maintenance of cell shape
YPTS_RS18920	COG1077	Cell shape determining protein MreB Mrl
YPTS_RS18925	COG2200	EAL domain
YPTS_RS18925	COG2199	diguanylate cyclase activity
YPTS_RS18930	COG0604	alcohol dehydrogenase
YPTS_RS18950	COG0511	ligase activity, forming carbon-carbon bonds
YPTS_RS18955	COG0439	Biotin carboxylase
YPTS_RS18960	COG3924	membrane
YPTS_RS18965	COG4145	pantothenate transmembrane transporter activity
YPTS_RS18975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPTS_RS18980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPTS_RS19000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPTS_RS19010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPTS_RS19015	COG3133	Outer membrane lipoprotein
YPTS_RS19025	COG1278	Cold shock
YPTS_RS19030	COG1278	Cold shock
YPTS_RS19035	COG1278	Cold shock
YPTS_RS19055	COG0625	glutathione transferase activity
YPTS_RS19065	COG1069	ribulokinase activity
YPTS_RS19075	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS19080	COG1129	ABC transporter
YPTS_RS19090	COG1560	Kdo2-lipid A biosynthetic process
YPTS_RS19100	COG0025	NhaP-type Na H and K H
YPTS_RS19105	COG2252	PERMEase
YPTS_RS19110	COG3077	Addiction module antitoxin, RelB DinJ family
YPTS_RS19120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPTS_RS19130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPTS_RS19135	COG0431	NADPH-dependent FMN reductase
YPTS_RS19140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPTS_RS19145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_RS19150	COG1869	D-ribose catabolic process
YPTS_RS19155	COG2207	Transcriptional regulator
YPTS_RS19160	COG0673	inositol 2-dehydrogenase activity
YPTS_RS19175	COG3501	Rhs element vgr protein
YPTS_RS19185	COG3209	COG3209 Rhs family protein
YPTS_RS19195	COG3501	Rhs element vgr protein
YPTS_RS19310	COG1175	transmembrane transport
YPTS_RS19315	COG3833	ABC-type maltose transport systems, permease component
YPTS_RS19330	COG0527	aspartate kinase activity
YPTS_RS19350	COG1414	Transcriptional regulator
YPTS_RS19360	COG2224	Isocitrate lyase
YPTS_RS19365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPTS_RS19420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPTS_RS19435	COG0551	DNA topoisomerase type I activity
YPTS_RS19445	COG0758	DNA mediated transformation
YPTS_RS19475	COG3036	rescue of stalled ribosome
YPTS_RS19480	COG0789	Transcriptional regulator
YPTS_RS19495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPTS_RS19510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPTS_RS19515	COG0201	protein transport
YPTS_RS19525	COG1841	ribosomal large subunit assembly
YPTS_RS19565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPTS_RS19570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPTS_RS19580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPTS_RS19585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPTS_RS19595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPTS_RS19605	COG0089	rRNA binding
YPTS_RS19620	COG0051	transcription antitermination factor activity, RNA binding
YPTS_RS19645	COG0049	tRNA binding
YPTS_RS19650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPTS_RS19670	COG2964	Protein conserved in bacteria
YPTS_RS19675	COG0545	Peptidyl-prolyl cis-trans isomerase
YPTS_RS19685	COG1047	Peptidyl-prolyl cis-trans
YPTS_RS19690	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPTS_RS19705	COG0488	(ABC) transporter
YPTS_RS19710	COG1216	Glycosyl transferase, family 2
YPTS_RS19720	COG2175	clavaminate synthase activity
YPTS_RS19725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPTS_RS19735	COG4521	taurine ABC transporter
YPTS_RS19745	COG0429	hydrolase of the alpha beta-hydrolase fold
YPTS_RS19755	COG3954	Phosphoribulokinase
YPTS_RS19765	COG1765	OsmC-like protein
YPTS_RS19775	COG1289	transmembrane transporter activity
YPTS_RS19790	COG0433	COG0433 Predicted ATPase
YPTS_RS19795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPTS_RS19800	COG1486	melibiose metabolic process
YPTS_RS19820	COG0402	S-adenosylhomocysteine deaminase activity
YPTS_RS19825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPTS_RS19845	COG0180	Tryptophanyl-tRNA synthetase
YPTS_RS19855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPTS_RS19880	COG4796	Type ii and iii secretion system protein
YPTS_RS19905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPTS_RS19910	COG0494	nUDIX hydrolase
YPTS_RS19925	COG1011	Hydrolase
YPTS_RS19930	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPTS_RS19955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPTS_RS19960	COG2183	response to ionizing radiation
YPTS_RS19970	COG1918	ferrous iron import across plasma membrane
YPTS_RS20005	COG1640	4-alpha-glucanotransferase
YPTS_RS20010	COG0058	SHG alpha-glucan phosphorylase activity
YPTS_RS20030	COG1349	DNA-binding transcription factor activity
YPTS_RS20055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPTS_RS20060	COG0058	SHG alpha-glucan phosphorylase activity
YPTS_RS20085	COG3275	phosphorelay sensor kinase activity
YPTS_RS20120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPTS_RS20125	COG2095	MarC family integral membrane protein
YPTS_RS20155	COG3265	gluconokinase activity
YPTS_RS20160	COG2610	gluconate transmembrane transporter activity
YPTS_RS20165	COG1609	Transcriptional regulator
YPTS_RS20170	COG1741	Belongs to the pirin family
YPTS_RS20190	COG0191	fructose-bisphosphate aldolase activity
YPTS_RS20205	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_RS20290	COG2081	HI0933 family
YPTS_RS20295	COG0306	phosphate transporter
YPTS_RS20305	COG0589	response to stress
YPTS_RS20325	COG0339	signal peptide processing
YPTS_RS20330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPTS_RS20335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPTS_RS20340	COG3835	regulator
YPTS_RS20345	COG2610	gluconate transmembrane transporter activity
YPTS_RS20350	COG1929	Belongs to the glycerate kinase type-1 family
YPTS_RS20375	COG1295	ribonuclease BN
YPTS_RS20380	COG2134	cdp-diacylglycerol pyrophosphatase
YPTS_RS20385	COG2982	Protein involved in outer membrane biogenesis
YPTS_RS20390	COG2200	EAL domain
YPTS_RS20395	COG1942	4-Oxalocrotonate Tautomerase
YPTS_RS20400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_RS20405	COG0612	Peptidase, M16
YPTS_RS20425	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPTS_RS20430	COG2199	diguanylate cyclase activity
YPTS_RS20430	COG2200	EAL domain
YPTS_RS20435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPTS_RS20440	COG4608	Belongs to the ABC transporter superfamily
YPTS_RS20445	COG0444	Belongs to the ABC transporter superfamily
YPTS_RS20450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPTS_RS20455	COG0601	transmembrane transport
YPTS_RS20460	COG0747	negative chemotaxis
YPTS_RS20470	COG2831	hemolysin activation secretion protein
YPTS_RS20485	COG2271	Major facilitator Superfamily
YPTS_RS20490	COG3851	Histidine kinase
YPTS_RS20495	COG2197	response regulator
YPTS_RS20500	COG2194	sulfuric ester hydrolase activity
YPTS_RS20545	COG4607	ABC-type enterochelin transport system periplasmic component
YPTS_RS20555	COG4605	iron ion homeostasis
YPTS_RS20560	COG4604	ABC transporter, ATP-binding protein
YPTS_RS20595	COG2003	Belongs to the UPF0758 family
YPTS_RS20635	COG1715	Restriction endonuclease
YPTS_RS20645	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
YPTS_RS20675	COG0582	viral genome integration into host DNA
YPTS_RS20680	COG2207	Transcriptional regulator
YPTS_RS20680	COG1609	Transcriptional regulator
YPTS_RS20685	COG4214	carbohydrate transport
YPTS_RS20695	COG4213	ABC transporter substrate-binding protein
YPTS_RS20705	COG1070	Carbohydrate kinase
YPTS_RS20715	COG3121	Chaperone
YPTS_RS20720	COG3188	usher protein
YPTS_RS20730	COG3274	enterobacterial common antigen metabolic process
YPTS_RS20740	COG2801	Transposase and inactivated derivatives
YPTS_RS20745	COG2423	ornithine cyclodeaminase activity
YPTS_RS20750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPTS_RS20755	COG0823	Involved in the tonB-independent uptake of proteins
YPTS_RS20760	COG5645	(Lipo)protein
YPTS_RS20780	COG3977	Valine--pyruvate aminotransferase
YPTS_RS20790	COG0366	Alpha amylase catalytic
YPTS_RS20805	COG2885	chlorophyll binding
YPTS_RS20815	COG2818	Glycosylase
YPTS_RS20835	COG2213	PTS system mannitol-specific
YPTS_RS20835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_RS20845	COG3722	fumarate hydratase activity
YPTS_RS20870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPTS_RS20880	COG3383	formate dehydrogenase (NAD+) activity
YPTS_RS20880	COG0243	molybdopterin cofactor binding
YPTS_RS20885	COG3383	formate dehydrogenase (NAD+) activity
YPTS_RS20885	COG0243	molybdopterin cofactor binding
YPTS_RS20890	COG0437	4 iron, 4 sulfur cluster binding
YPTS_RS20895	COG2864	formate dehydrogenase
YPTS_RS20910	COG3276	selenocysteine insertion sequence binding
YPTS_RS20950	COG2186	Transcriptional regulator
YPTS_RS20955	COG0477	Major facilitator Superfamily
YPTS_RS20965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_RS20995	COG1522	sequence-specific DNA binding
YPTS_RS21000	COG0716	FMN binding
YPTS_RS21015	COG3312	ion transport
YPTS_RS21070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPTS_RS21075	COG0573	inorganic phosphate transmembrane transporter activity
YPTS_RS21080	COG0581	inorganic phosphate transmembrane transporter activity
YPTS_RS21090	COG0704	Plays a role in the regulation of phosphate uptake
YPTS_RS21100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_RS21105	COG0765	amino acid transport
YPTS_RS21110	COG0765	amino acid transport
YPTS_RS21115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPTS_RS21120	COG2252	PERMEase
YPTS_RS21145	COG0706	membrane insertase activity
YPTS_RS21155	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPTS_RS21355	COG1217	gtp-binding protein TYPA
YPTS_RS21400	COG2982	Protein involved in outer membrane biogenesis
YPTS_RS21410	COG2233	PERMEase
YPTS_RS21445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPTS_RS21555	COG0156	8-amino-7-oxononanoate synthase activity
YPTS_RS21640	COG4695	Portal protein
YPTS_RS21650	COG3210	domain, Protein
