locus-tag	class	description
BZ22_RS00005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_RS00010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_RS00015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_RS00020	COG2207	Transcriptional regulator
BZ22_RS00030	COG4269	membrane
BZ22_RS00045	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BZ22_RS00080	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BZ22_RS00085	COG0582	viral genome integration into host DNA
BZ22_RS00095	COG0795	lipopolysaccharide-transporting ATPase activity
BZ22_RS00100	COG0795	lipopolysaccharide-transporting ATPase activity
BZ22_RS00110	COG2927	DNA polymerase III (CHI subunit)
BZ22_RS00125	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BZ22_RS00135	COG2731	YhcH YjgK YiaL family protein
BZ22_RS00145	COG0601	transmembrane transport
BZ22_RS00150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ22_RS00155	COG0444	Belongs to the ABC transporter superfamily
BZ22_RS00160	COG4608	Belongs to the ABC transporter superfamily
BZ22_RS00175	COG2188	Transcriptional regulator
BZ22_RS00180	COG3624	Phosphonate C-P lyase system protein PhnG
BZ22_RS00185	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BZ22_RS00190	COG3626	phosphonate metabolism
BZ22_RS00195	COG3627	carbon phosphorus lyase activity
BZ22_RS00200	COG4107	phosphonate C-P lyase system protein PhnK
BZ22_RS00205	COG4778	phosphonate C-P lyase system protein PhnL
BZ22_RS00210	COG3454	Phosphonate metabolism
BZ22_RS00215	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BZ22_RS00220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BZ22_RS00225	COG0702	epimerase
BZ22_RS00240	COG3842	ATPase activity
BZ22_RS00245	COG0395	ABC-type sugar transport system, permease component
BZ22_RS00250	COG1175	transmembrane transport
BZ22_RS00255	COG1653	transport
BZ22_RS00280	COG3153	acetyltransferase
BZ22_RS00285	COG3154	lipid carrier protein
BZ22_RS00295	COG0826	peptidase U32
BZ22_RS00300	COG0826	peptidase U32
BZ22_RS00310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_RS00320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZ22_RS00340	COG0513	Belongs to the DEAD box helicase family
BZ22_RS00375	COG0195	Participates in both transcription termination and antitermination
BZ22_RS00395	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ22_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BZ22_RS00420	COG1534	Rna-binding protein
BZ22_RS00430	COG2027	D-alanyl-D-alanine carboxypeptidase
BZ22_RS00435	COG0745	RESPONSE REGULATOR receiver
BZ22_RS00440	COG0642	Histidine kinase
BZ22_RS00505	COG0697	spore germination
BZ22_RS00520	COG0142	geranyltranstransferase activity
BZ22_RS00530	COG3423	Transcriptional regulator
BZ22_RS00555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BZ22_RS00565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BZ22_RS00570	COG2105	PFAM AIG2 family protein
BZ22_RS00575	COG2911	Protein conserved in bacteria
BZ22_RS00580	COG0729	surface antigen
BZ22_RS00590	COG1253	flavin adenine dinucleotide binding
BZ22_RS00600	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BZ22_RS00610	COG0737	Belongs to the 5'-nucleotidase family
BZ22_RS00620	COG0545	Peptidyl-prolyl cis-trans isomerase
BZ22_RS00625	COG3061	Opacity-associated protein A
BZ22_RS00640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BZ22_RS00650	COG0360	Binds together with S18 to 16S ribosomal RNA
BZ22_RS00660	COG1073	alpha beta
BZ22_RS00665	COG3650	response to hydrogen peroxide
BZ22_RS00670	COG1960	acyl-CoA dehydrogenase activity
BZ22_RS00675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ22_RS00680	COG0557	exoribonuclease II activity
BZ22_RS00695	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BZ22_RS00700	COG0330	HflC and HflK could
BZ22_RS00705	COG0330	HflC and HflK could
BZ22_RS00710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BZ22_RS00730	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ22_RS00735	COG0802	atpase or kinase
BZ22_RS00740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BZ22_RS00740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZ22_RS00745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BZ22_RS00790	COG1511	domain protein
BZ22_RS00790	COG3264	Mechanosensitive ion channel
BZ22_RS00805	COG1053	succinate dehydrogenase
BZ22_RS00810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZ22_RS00820	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BZ22_RS00865	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ22_RS00880	COG3383	formate dehydrogenase (NAD+) activity
BZ22_RS00885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_RS00890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_RS00890	COG0493	'glutamate synthase
BZ22_RS00895	COG1309	transcriptional regulator
BZ22_RS00965	COG1454	alcohol dehydrogenase
BZ22_RS00975	COG0629	single-stranded DNA binding
BZ22_RS00980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BZ22_RS00985	COG2315	Protein conserved in bacteria
BZ22_RS00990	COG1448	Aminotransferase
BZ22_RS01015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ22_RS01020	COG0735	belongs to the Fur family
BZ22_RS01030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BZ22_RS01075	COG3121	Chaperone
BZ22_RS01135	COG1358	cellular component organization or biogenesis
BZ22_RS01160	COG3721	Heme iron utilization protein
BZ22_RS01165	COG0702	epimerase
BZ22_RS01175	COG4771	TonB-dependent receptor
BZ22_RS01180	COG3720	iron ion transport
BZ22_RS01185	COG4558	Periplasmic binding protein
BZ22_RS01190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_RS01200	COG0626	cystathionine gamma-synthase activity
BZ22_RS01205	COG0814	amino acid
BZ22_RS01210	COG0583	DNA-binding transcription factor activity
BZ22_RS01215	COG0425	Belongs to the sulfur carrier protein TusA family
BZ22_RS01220	COG2391	methyltransferase activity
BZ22_RS01330	COG1301	dicarboxylic acid transport
BZ22_RS01340	COG3162	membrane
BZ22_RS01355	COG2801	Transposase and inactivated derivatives
BZ22_RS01395	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BZ22_RS01400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BZ22_RS01405	COG1739	Uncharacterized protein family UPF0029
BZ22_RS01450	COG0805	protein transport
BZ22_RS01460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZ22_RS01480	COG1322	Protein conserved in bacteria
BZ22_RS01485	COG0586	Pfam SNARE associated Golgi protein
BZ22_RS01490	COG1966	Carbon starvation protein
BZ22_RS01505	COG0412	Dienelactone hydrolase
BZ22_RS01515	COG0583	DNA-binding transcription factor activity
BZ22_RS01520	COG0697	spore germination
BZ22_RS01535	COG0679	Auxin Efflux Carrier
BZ22_RS01540	COG0584	glycerophosphoryl diester phosphodiesterase
BZ22_RS01600	COG0410	ABC transporter
BZ22_RS01610	COG4177	L-phenylalanine transmembrane transporter activity
BZ22_RS01620	COG0683	leucine binding
BZ22_RS01635	COG2177	Part of the ABC transporter FtsEX involved in
BZ22_RS01640	COG2884	Cell division ATP-binding protein ftsE
BZ22_RS01645	COG0552	protein localization to endoplasmic reticulum
BZ22_RS01645	COG0552	protein localization to endoplasmic reticulum
BZ22_RS01655	COG0742	ribosomal rna small subunit methyltransferase
BZ22_RS01660	COG3776	membrane
BZ22_RS01675	COG3714	YhhN family
BZ22_RS01690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BZ22_RS01700	COG0247	lactate metabolic process
BZ22_RS01710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ22_RS01720	COG0584	glycerophosphoryl diester phosphodiesterase
BZ22_RS01730	COG0561	phosphatase activity
BZ22_RS01735	COG2267	carboxylic ester hydrolase activity
BZ22_RS01740	COG1280	lysine exporter protein (LysE YggA)
BZ22_RS01745	COG1280	lysine exporter protein (LysE YggA)
BZ22_RS01750	COG0514	ATP-dependent DNA helicase (RecQ)
BZ22_RS01755	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BZ22_RS01760	COG2050	protein possibly involved in aromatic compounds catabolism
BZ22_RS01775	COG5564	TIM-barrel signal transduction protein
BZ22_RS01780	COG5441	Belongs to the UPF0261 family
BZ22_RS01790	COG0210	DNA helicase
BZ22_RS01795	COG1011	Hydrolase
BZ22_RS01800	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BZ22_RS01805	COG3159	Protein conserved in bacteria
BZ22_RS01825	COG3072	Adenylate cyclase
BZ22_RS01835	COG1587	Uroporphyrinogen-III synthase
BZ22_RS01840	COG2959	enzyme of heme biosynthesis
BZ22_RS01845	COG3071	HemY protein
BZ22_RS01870	COG1113	amino acid transport
BZ22_RS01890	COG2244	polysaccharide biosynthetic process
BZ22_RS01895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BZ22_RS01900	COG0456	acetyltransferase
BZ22_RS01905	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BZ22_RS01910	COG1088	dTDP-glucose 4,6-dehydratase activity
BZ22_RS01915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BZ22_RS01920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BZ22_RS01925	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZ22_RS01930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BZ22_RS01935	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BZ22_RS01940	COG3118	belongs to the thioredoxin family
BZ22_RS01965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ22_RS01985	COG3121	Chaperone
BZ22_RS02000	COG3121	Chaperone
BZ22_RS02040	COG0583	DNA-binding transcription factor activity
BZ22_RS02075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ22_RS02080	COG3978	acetolactate synthase activity
BZ22_RS02095	COG3085	chromosome segregation
BZ22_RS02105	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS02110	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS02115	COG1129	ABC transporter
BZ22_RS02120	COG1879	ABC-type sugar transport system periplasmic component
BZ22_RS02200	COG0678	peroxiredoxin activity
BZ22_RS02200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ22_RS02205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ22_RS02230	COG1629	transport
BZ22_RS02275	COG0527	aspartate kinase activity
BZ22_RS02275	COG0460	homoserine dehydrogenase
BZ22_RS02280	COG0626	cystathionine gamma-synthase activity
BZ22_RS02285	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BZ22_RS02295	COG4682	membrane
BZ22_RS02305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BZ22_RS02315	COG1609	Transcriptional regulator
BZ22_RS02320	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ22_RS02335	COG1575	Belongs to the MenA family. Type 1 subfamily
BZ22_RS02380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BZ22_RS02385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZ22_RS02390	COG1494	fructose-1,6-bisphosphatase
BZ22_RS02400	COG3152	Membrane
BZ22_RS02415	COG0583	DNA-binding transcription factor activity
BZ22_RS02420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BZ22_RS02425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BZ22_RS02430	COG0471	metal ion transport
BZ22_RS02440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BZ22_RS02460	COG3678	ATP-independent chaperone mediated protein folding
BZ22_RS02465	COG0745	RESPONSE REGULATOR receiver
BZ22_RS02470	COG2205	protein histidine kinase activity
BZ22_RS02475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ22_RS02475	COG2169	Transcriptional regulator
BZ22_RS02480	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BZ22_RS02485	COG1045	serine acetyltransferase
BZ22_RS02505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ22_RS02510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZ22_RS02520	COG4942	peptidase
BZ22_RS02525	COG2861	carbohydrate metabolic process
BZ22_RS02535	COG0156	8-amino-7-oxononanoate synthase activity
BZ22_RS02545	COG0859	PFAM glycosyl transferase family 9
BZ22_RS02550	COG0859	PFAM glycosyl transferase family 9
BZ22_RS02555	COG1519	Transferase
BZ22_RS02590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZ22_RS02615	COG1561	YicC-like family, N-terminal region
BZ22_RS02675	COG2860	membrane
BZ22_RS02690	COG1758	RNA polymerase activity
BZ22_RS02695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZ22_RS02700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ22_RS02705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZ22_RS02710	COG0786	glutamate:sodium symporter activity
BZ22_RS02715	COG2233	PERMEase
BZ22_RS02720	COG2982	Protein involved in outer membrane biogenesis
BZ22_RS02725	COG0456	acetyltransferase
BZ22_RS02740	COG1011	Hydrolase
BZ22_RS02755	COG0174	glutamine synthetase
BZ22_RS02760	COG3852	Histidine kinase
BZ22_RS02770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ22_RS02790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ22_RS02790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ22_RS02795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ22_RS02800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BZ22_RS02805	COG3084	Protein conserved in bacteria
BZ22_RS02815	COG1763	Mo-molybdopterin cofactor biosynthetic process
BZ22_RS02820	COG3328	transposase activity
BZ22_RS02850	COG2186	Transcriptional regulator
BZ22_RS02855	COG0477	Major facilitator Superfamily
BZ22_RS02865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_RS02895	COG1522	sequence-specific DNA binding
BZ22_RS02900	COG0716	FMN binding
BZ22_RS02915	COG3312	ion transport
BZ22_RS02970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BZ22_RS02975	COG0573	inorganic phosphate transmembrane transporter activity
BZ22_RS02980	COG0581	inorganic phosphate transmembrane transporter activity
BZ22_RS02990	COG0704	Plays a role in the regulation of phosphate uptake
BZ22_RS03000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_RS03005	COG0765	amino acid transport
BZ22_RS03010	COG0765	amino acid transport
BZ22_RS03015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ22_RS03020	COG2252	PERMEase
BZ22_RS03050	COG0706	membrane insertase activity
BZ22_RS03060	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BZ22_RS03070	COG0592	DNA-directed DNA polymerase activity
BZ22_RS03085	COG0187	DNA topoisomerase II activity
BZ22_RS03090	COG0561	phosphatase activity
BZ22_RS03095	COG2423	ornithine cyclodeaminase activity
BZ22_RS03100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZ22_RS03105	COG0823	Involved in the tonB-independent uptake of proteins
BZ22_RS03110	COG5645	(Lipo)protein
BZ22_RS03130	COG3977	Valine--pyruvate aminotransferase
BZ22_RS03140	COG0366	Alpha amylase catalytic
BZ22_RS03155	COG2885	chlorophyll binding
BZ22_RS03165	COG2818	Glycosylase
BZ22_RS03185	COG2213	PTS system mannitol-specific
BZ22_RS03185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_RS03195	COG3722	fumarate hydratase activity
BZ22_RS03220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZ22_RS03230	COG3383	formate dehydrogenase (NAD+) activity
BZ22_RS03230	COG0243	molybdopterin cofactor binding
BZ22_RS03235	COG3383	formate dehydrogenase (NAD+) activity
BZ22_RS03235	COG0243	molybdopterin cofactor binding
BZ22_RS03240	COG0437	4 iron, 4 sulfur cluster binding
BZ22_RS03245	COG2864	formate dehydrogenase
BZ22_RS03260	COG3276	selenocysteine insertion sequence binding
BZ22_RS03295	COG3274	enterobacterial common antigen metabolic process
BZ22_RS03305	COG3188	usher protein
BZ22_RS03310	COG3121	Chaperone
BZ22_RS03320	COG1070	Carbohydrate kinase
BZ22_RS03330	COG4213	ABC transporter substrate-binding protein
BZ22_RS03340	COG4214	carbohydrate transport
BZ22_RS03345	COG1609	Transcriptional regulator
BZ22_RS03345	COG2207	Transcriptional regulator
BZ22_RS03350	COG0582	viral genome integration into host DNA
BZ22_RS03380	COG2801	Transposase and inactivated derivatives
BZ22_RS03385	COG4604	ABC transporter, ATP-binding protein
BZ22_RS03390	COG4605	iron ion homeostasis
BZ22_RS03400	COG4607	ABC-type enterochelin transport system periplasmic component
BZ22_RS03445	COG2194	sulfuric ester hydrolase activity
BZ22_RS03450	COG2197	response regulator
BZ22_RS03455	COG3851	Histidine kinase
BZ22_RS03460	COG2271	Major facilitator Superfamily
BZ22_RS03475	COG2831	hemolysin activation secretion protein
BZ22_RS03485	COG0747	negative chemotaxis
BZ22_RS03490	COG0601	transmembrane transport
BZ22_RS03495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ22_RS03500	COG0444	Belongs to the ABC transporter superfamily
BZ22_RS03505	COG4608	Belongs to the ABC transporter superfamily
BZ22_RS03515	COG2200	EAL domain
BZ22_RS03515	COG2199	diguanylate cyclase activity
BZ22_RS03520	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZ22_RS03540	COG0612	Peptidase, M16
BZ22_RS03545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_RS03550	COG1942	4-Oxalocrotonate Tautomerase
BZ22_RS03555	COG2200	EAL domain
BZ22_RS03560	COG2982	Protein involved in outer membrane biogenesis
BZ22_RS03565	COG2134	cdp-diacylglycerol pyrophosphatase
BZ22_RS03570	COG1295	ribonuclease BN
BZ22_RS03595	COG1929	Belongs to the glycerate kinase type-1 family
BZ22_RS03600	COG2610	gluconate transmembrane transporter activity
BZ22_RS03605	COG3835	regulator
BZ22_RS03610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ22_RS03615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BZ22_RS03620	COG0339	signal peptide processing
BZ22_RS03640	COG0589	response to stress
BZ22_RS03650	COG0306	phosphate transporter
BZ22_RS03655	COG2081	HI0933 family
BZ22_RS03670	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS03685	COG0191	fructose-bisphosphate aldolase activity
BZ22_RS03705	COG1741	Belongs to the pirin family
BZ22_RS03710	COG1609	Transcriptional regulator
BZ22_RS03715	COG2610	gluconate transmembrane transporter activity
BZ22_RS03720	COG3265	gluconokinase activity
BZ22_RS03740	COG2095	MarC family integral membrane protein
BZ22_RS03745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ22_RS03770	COG3275	phosphorelay sensor kinase activity
BZ22_RS03795	COG0058	SHG alpha-glucan phosphorylase activity
BZ22_RS03800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ22_RS03820	COG1349	DNA-binding transcription factor activity
BZ22_RS03840	COG0058	SHG alpha-glucan phosphorylase activity
BZ22_RS03845	COG1640	4-alpha-glucanotransferase
BZ22_RS03880	COG1918	ferrous iron import across plasma membrane
BZ22_RS03890	COG2183	response to ionizing radiation
BZ22_RS03895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ22_RS03920	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BZ22_RS03925	COG1011	Hydrolase
BZ22_RS03940	COG0494	nUDIX hydrolase
BZ22_RS04035	COG3179	chitinase
BZ22_RS04050	COG4382	Mu-like prophage protein Gp16
BZ22_RS04125	COG3423	Transcriptional regulator
BZ22_RS04135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BZ22_RS04165	COG4796	Type ii and iii secretion system protein
BZ22_RS04190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BZ22_RS04195	COG0546	phosphoglycolate phosphatase activity
BZ22_RS04200	COG0180	Tryptophanyl-tRNA synthetase
BZ22_RS04220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BZ22_RS04225	COG0402	S-adenosylhomocysteine deaminase activity
BZ22_RS04245	COG1486	melibiose metabolic process
BZ22_RS04250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ22_RS04255	COG0433	COG0433 Predicted ATPase
BZ22_RS04270	COG1289	transmembrane transporter activity
BZ22_RS04280	COG1765	OsmC-like protein
BZ22_RS04285	COG3157	Type VI secretion system effector, Hcp
BZ22_RS04300	COG3954	Phosphoribulokinase
BZ22_RS04310	COG0429	hydrolase of the alpha beta-hydrolase fold
BZ22_RS04320	COG4521	taurine ABC transporter
BZ22_RS04330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ22_RS04335	COG2175	clavaminate synthase activity
BZ22_RS04345	COG1216	Glycosyl transferase, family 2
BZ22_RS04350	COG0488	(ABC) transporter
BZ22_RS04365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BZ22_RS04370	COG1047	Peptidyl-prolyl cis-trans
BZ22_RS04380	COG0545	Peptidyl-prolyl cis-trans isomerase
BZ22_RS04385	COG2964	Protein conserved in bacteria
BZ22_RS04405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BZ22_RS04410	COG0049	tRNA binding
BZ22_RS04440	COG0051	transcription antitermination factor activity, RNA binding
BZ22_RS04455	COG0089	rRNA binding
BZ22_RS04465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZ22_RS04475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BZ22_RS04480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BZ22_RS04490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BZ22_RS04495	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BZ22_RS04535	COG1841	ribosomal large subunit assembly
BZ22_RS04545	COG0201	protein transport
BZ22_RS04550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ22_RS04565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BZ22_RS04580	COG0789	Transcriptional regulator
BZ22_RS04585	COG3036	rescue of stalled ribosome
BZ22_RS04615	COG0758	DNA mediated transformation
BZ22_RS04625	COG0551	DNA topoisomerase type I activity
BZ22_RS04640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BZ22_RS04725	COG0250	Participates in transcription elongation, termination and antitermination
BZ22_RS04780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZ22_RS04820	COG1515	deoxyribonuclease V activity
BZ22_RS04840	COG0151	Belongs to the GarS family
BZ22_RS04895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BZ22_RS04900	COG2224	Isocitrate lyase
BZ22_RS04910	COG1414	Transcriptional regulator
BZ22_RS04935	COG0527	aspartate kinase activity
BZ22_RS04950	COG3833	ABC-type maltose transport systems, permease component
BZ22_RS04955	COG1175	transmembrane transport
BZ22_RS05070	COG3501	Rhs element vgr protein
BZ22_RS05115	COG3209	COG3209 Rhs family protein
BZ22_RS05125	COG3501	Rhs element vgr protein
BZ22_RS05135	COG0673	inositol 2-dehydrogenase activity
BZ22_RS05140	COG2207	Transcriptional regulator
BZ22_RS05145	COG1869	D-ribose catabolic process
BZ22_RS05150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_RS05155	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BZ22_RS05165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ22_RS05175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ22_RS05185	COG3077	Addiction module antitoxin, RelB DinJ family
BZ22_RS05190	COG2252	PERMEase
BZ22_RS05195	COG3328	transposase activity
BZ22_RS05200	COG0025	NhaP-type Na H and K H
BZ22_RS05210	COG1560	Kdo2-lipid A biosynthetic process
BZ22_RS05220	COG1129	ABC transporter
BZ22_RS05225	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS05235	COG1069	ribulokinase activity
BZ22_RS05245	COG0625	glutathione transferase activity
BZ22_RS05260	COG1278	Cold shock
BZ22_RS05265	COG1278	Cold shock
BZ22_RS05270	COG1278	Cold shock
BZ22_RS05285	COG3133	Outer membrane lipoprotein
BZ22_RS05290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ22_RS05300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ22_RS05325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BZ22_RS05330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ22_RS05340	COG4145	pantothenate transmembrane transporter activity
BZ22_RS05345	COG3924	membrane
BZ22_RS05350	COG0439	Biotin carboxylase
BZ22_RS05355	COG0511	ligase activity, forming carbon-carbon bonds
BZ22_RS05375	COG0604	alcohol dehydrogenase
BZ22_RS05380	COG2199	diguanylate cyclase activity
BZ22_RS05380	COG2200	EAL domain
BZ22_RS05385	COG1077	Cell shape determining protein MreB Mrl
BZ22_RS05390	COG1792	Involved in formation and maintenance of cell shape
BZ22_RS05395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BZ22_RS05400	COG0424	maF-like protein
BZ22_RS05405	COG1530	ribonuclease E activity
BZ22_RS05410	COG3164	Protein of unknown function
BZ22_RS05415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ22_RS05420	COG0312	modulator of DNA gyrase
BZ22_RS05465	COG0583	DNA-binding transcription factor activity
BZ22_RS05495	COG2732	(Barnase) inhibitor
BZ22_RS05505	COG0312	modulator of DNA gyrase
BZ22_RS05515	COG3783	Cytochrome b(562)
BZ22_RS05520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ22_RS05525	COG0366	Alpha amylase catalytic
BZ22_RS05530	COG1263	PTS System
BZ22_RS05530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_RS05535	COG1609	Transcriptional regulator
BZ22_RS05560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_RS05580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BZ22_RS05585	COG1137	ATPase activity
BZ22_RS05590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BZ22_RS05595	COG3117	lipopolysaccharide transmembrane transporter activity
BZ22_RS05600	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BZ22_RS05605	COG0517	IMP dehydrogenase activity
BZ22_RS05605	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BZ22_RS05610	COG0530	calcium, potassium:sodium antiporter activity
BZ22_RS05615	COG1127	ABC transporter
BZ22_RS05620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BZ22_RS05625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZ22_RS05630	COG2854	intermembrane phospholipid transfer
BZ22_RS05635	COG3113	response to antibiotic
BZ22_RS05640	COG5007	Belongs to the BolA IbaG family
BZ22_RS05650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ22_RS05655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ22_RS05660	COG3105	Protein conserved in bacteria
BZ22_RS05665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BZ22_RS05685	COG0625	glutathione transferase activity
BZ22_RS05690	COG2969	positive regulation of protein catabolic process
BZ22_RS05700	COG0493	'glutamate synthase
BZ22_RS05705	COG0070	glutamate synthase
BZ22_RS05705	COG0069	glutamate synthase activity
BZ22_RS05705	COG0067	glutamate synthase
BZ22_RS05710	COG1242	4 iron, 4 sulfur cluster binding
BZ22_RS05720	COG2198	Histidine kinase
BZ22_RS05720	COG5002	protein histidine kinase activity
BZ22_RS05720	COG0784	Response regulator, receiver
BZ22_RS05730	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BZ22_RS05740	COG2823	Periplasmic or secreted lipoprotein
BZ22_RS05760	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BZ22_RS05765	COG1741	Belongs to the pirin family
BZ22_RS05770	COG0583	DNA-binding transcription factor activity
BZ22_RS05775	COG0435	Glutathione S-transferase
BZ22_RS05780	COG2259	Doxx family
BZ22_RS05790	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BZ22_RS05795	COG4575	ribosome binding
BZ22_RS05815	COG0586	Pfam SNARE associated Golgi protein
BZ22_RS05830	COG2271	Major facilitator Superfamily
BZ22_RS05850	COG2721	sulfolactate sulfo-lyase activity
BZ22_RS05865	COG0673	inositol 2-dehydrogenase activity
BZ22_RS05870	COG1451	nucleotide metabolic process
BZ22_RS05885	COG0446	pyridine nucleotide-disulphide oxidoreductase
BZ22_RS05885	COG1902	pentaerythritol trinitrate reductase activity
BZ22_RS05890	COG3247	response to pH
BZ22_RS05910	COG4245	von Willebrand factor, type A
BZ22_RS05925	COG4245	von Willebrand factor, type A
BZ22_RS05930	COG2831	hemolysin activation secretion protein
BZ22_RS05935	COG3210	domain, Protein
BZ22_RS05960	COG3210	domain, Protein
BZ22_RS05985	COG3210	domain, Protein
BZ22_RS05990	COG3210	domain, Protein
BZ22_RS06010	COG3842	ATPase activity
BZ22_RS06015	COG3459	Glycosyltransferase 36 associated
BZ22_RS06020	COG1609	Transcriptional regulator
BZ22_RS06025	COG2182	Extracellular solute-binding protein
BZ22_RS06035	COG0395	ABC-type sugar transport system, permease component
BZ22_RS06055	COG1289	transmembrane transporter activity
BZ22_RS06080	COG0436	Aminotransferase
BZ22_RS06100	COG0251	oxidation-reduction process
BZ22_RS06140	COG3157	Type VI secretion system effector, Hcp
BZ22_RS06180	COG3561	AntA/AntB antirepressor
BZ22_RS06270	COG0358	DNA primase activity
BZ22_RS06275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BZ22_RS06290	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BZ22_RS06305	COG4991	sh3 domain protein
BZ22_RS06310	COG3025	triphosphatase activity
BZ22_RS06325	COG0531	amino acid
BZ22_RS06345	COG3384	dioxygenase
BZ22_RS06350	COG0754	glutathionylspermidine amidase activity
BZ22_RS06365	COG1538	Outer membrane efflux protein
BZ22_RS06370	COG0494	nUDIX hydrolase
BZ22_RS06375	COG3151	Protein conserved in bacteria
BZ22_RS06380	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BZ22_RS06385	COG3150	esterase
BZ22_RS06395	COG0583	DNA-binding transcription factor activity
BZ22_RS06400	COG2249	NAD(P)H dehydrogenase (quinone) activity
BZ22_RS06405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BZ22_RS06415	COG2132	Multicopper oxidase
BZ22_RS06425	COG0656	L-ascorbic acid biosynthetic process
BZ22_RS06435	COG1979	alcohol dehydrogenase
BZ22_RS06440	COG2207	Transcriptional regulator
BZ22_RS06445	COG0586	Pfam SNARE associated Golgi protein
BZ22_RS06450	COG0626	cystathionine gamma-synthase activity
BZ22_RS06455	COG0811	peptide transport
BZ22_RS06460	COG0848	biopolymer transport protein
BZ22_RS06510	COG4964	Belongs to the GSP D family
BZ22_RS06545	COG3397	chitin binding
BZ22_RS06550	COG3469	chitinase activity
BZ22_RS06575	COG4592	Periplasmic binding protein
BZ22_RS06595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ22_RS06600	COG1684	flagellar biosynthetic protein fliR
BZ22_RS06605	COG1987	bacterial-type flagellum assembly
BZ22_RS06630	COG1677	Flagellar hook-basal body complex protein FliE
BZ22_RS06670	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BZ22_RS06675	COG1815	bacterial-type flagellum-dependent cell motility
BZ22_RS06680	COG1558	bacterial-type flagellum-dependent cell motility
BZ22_RS06685	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BZ22_RS06705	COG3710	Transcriptional regulator
BZ22_RS06725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BZ22_RS06755	COG3133	Outer membrane lipoprotein
BZ22_RS06765	COG5001	Diguanylate cyclase
BZ22_RS06770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_RS06810	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BZ22_RS06815	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ22_RS06820	COG4771	TonB-dependent receptor
BZ22_RS06830	COG3433	isochorismatase activity
BZ22_RS06830	COG2226	methyltransferase
BZ22_RS06830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ22_RS06840	COG3433	isochorismatase activity
BZ22_RS06840	COG2226	methyltransferase
BZ22_RS06840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ22_RS06865	COG1132	(ABC) transporter
BZ22_RS06865	COG2375	cellular response to nickel ion
BZ22_RS06870	COG1132	(ABC) transporter
BZ22_RS06885	COG2610	gluconate transmembrane transporter activity
BZ22_RS06895	COG3501	Rhs element vgr protein
BZ22_RS06905	COG3209	COG3209 Rhs family protein
BZ22_RS06915	COG3209	COG3209 Rhs family protein
BZ22_RS06925	COG3209	COG3209 Rhs family protein
BZ22_RS06935	COG3209	COG3209 Rhs family protein
BZ22_RS06965	COG0471	metal ion transport
BZ22_RS06970	COG1609	Transcriptional regulator
BZ22_RS06980	COG2211	Major facilitator Superfamily
BZ22_RS07025	COG2771	luxR family
BZ22_RS07030	COG3916	Acyl-homoserine-lactone synthase
BZ22_RS07135	COG1982	Orn Lys Arg decarboxylase major
BZ22_RS07140	COG1879	ABC-type sugar transport system periplasmic component
BZ22_RS07145	COG1129	ABC transporter
BZ22_RS07150	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS07155	COG4774	siderophore transport
BZ22_RS07175	COG1194	a g-specific adenine glycosylase
BZ22_RS07185	COG3171	Protein conserved in bacteria
BZ22_RS07200	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BZ22_RS07200	COG3064	Membrane
BZ22_RS07200	COG1073	alpha beta
BZ22_RS07205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ22_RS07220	COG0762	integral membrane protein
BZ22_RS07225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BZ22_RS07230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BZ22_RS07235	COG2805	Type II/IV secretion system protein
BZ22_RS07245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ22_RS07260	COG0189	ligase activity
BZ22_RS07265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BZ22_RS07275	COG2356	endonuclease I
BZ22_RS07290	COG1166	arginine decarboxylase activity
BZ22_RS07310	COG0501	Belongs to the peptidase M48B family
BZ22_RS07315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BZ22_RS07330	COG0191	fructose-bisphosphate aldolase activity
BZ22_RS07365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BZ22_RS07370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BZ22_RS07385	COG0006	proline dipeptidase activity
BZ22_RS07390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ22_RS07395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ22_RS07425	COG5295	Hep Hag repeat protein
BZ22_RS07435	COG1272	protein, Hemolysin III
BZ22_RS07460	COG0745	RESPONSE REGULATOR receiver
BZ22_RS07465	COG2205	protein histidine kinase activity
BZ22_RS07470	COG4452	Inner membrane protein CreD
BZ22_RS07475	COG0716	FMN binding
BZ22_RS07545	COG4695	Portal protein
BZ22_RS07640	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZ22_RS07670	COG4974	Belongs to the 'phage' integrase family
BZ22_RS07675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ22_RS07680	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BZ22_RS07700	COG0582	viral genome integration into host DNA
BZ22_RS07890	COG1695	Transcriptional regulator
BZ22_RS07895	COG0791	NLP P60 protein
BZ22_RS07905	COG1879	ABC-type sugar transport system periplasmic component
BZ22_RS07910	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS07915	COG1129	ABC transporter
BZ22_RS07925	COG2182	Extracellular solute-binding protein
BZ22_RS07930	COG1175	transmembrane transport
BZ22_RS07935	COG3833	ABC-type maltose transport systems, permease component
BZ22_RS07940	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BZ22_RS07945	COG1874	Beta-galactosidase
BZ22_RS07950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_RS07950	COG1263	PTS System
BZ22_RS07970	COG2271	Major facilitator Superfamily
BZ22_RS08000	COG3119	arylsulfatase activity
BZ22_RS08005	COG0641	radical SAM
BZ22_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS08025	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_RS08030	COG3716	PTS system mannose fructose sorbose family IID component
BZ22_RS08035	COG3715	PTS system
BZ22_RS08040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_RS08045	COG2222	sugar isomerase
BZ22_RS08055	COG1349	DNA-binding transcription factor activity
BZ22_RS08060	COG3119	arylsulfatase activity
BZ22_RS08090	COG0288	reversible hydration of carbon dioxide
BZ22_RS08110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BZ22_RS08175	COG0840	transmembrane signaling receptor activity
BZ22_RS08195	COG2814	Major facilitator Superfamily
BZ22_RS08200	COG0583	DNA-binding transcription factor activity
BZ22_RS08210	COG1609	Transcriptional regulator
BZ22_RS08240	COG0667	Aldo Keto reductase
BZ22_RS08305	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BZ22_RS08315	COG1074	ATP-dependent DNA helicase activity
BZ22_RS08320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BZ22_RS08330	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ22_RS08350	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BZ22_RS08355	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BZ22_RS08360	COG2166	iron-sulfur cluster assembly
BZ22_RS08365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BZ22_RS08370	COG0583	DNA-binding transcription factor activity
BZ22_RS08375	COG2363	Small membrane protein
BZ22_RS08390	COG1611	Belongs to the LOG family
BZ22_RS08405	COG3098	single-species biofilm formation
BZ22_RS08410	COG0564	pseudouridine synthase activity
BZ22_RS08470	COG0575	Belongs to the CDS family
BZ22_RS08475	COG0750	zinc metalloprotease
BZ22_RS08490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BZ22_RS08515	COG0587	DNA-directed DNA polymerase activity
BZ22_RS08525	COG0346	lactoylglutathione lyase activity
BZ22_RS08540	COG4568	rho-dependent transcription termination
BZ22_RS08550	COG4681	YaeQ
BZ22_RS08560	COG3015	lipoprotein NlpE involved in copper resistance
BZ22_RS08570	COG1720	tRNA m6t6A37 methyltransferase activity
BZ22_RS08580	COG1464	Belongs to the NlpA lipoprotein family
BZ22_RS08585	COG2011	ABC-type metal ion transport system permease component
BZ22_RS08595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BZ22_RS08630	COG0656	L-ascorbic acid biosynthetic process
BZ22_RS08645	COG0741	lytic transglycosylase activity
BZ22_RS08645	COG1388	LysM domain
BZ22_RS08655	COG2226	methyltransferase
BZ22_RS08675	COG1953	Uracil, thiamine, allantoin
BZ22_RS08685	COG2113	Glycine betaine
BZ22_RS08690	COG4176	ABC-type proline glycine betaine transport system permease component
BZ22_RS08695	COG4175	Glycine betaine
BZ22_RS08700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZ22_RS08740	COG1278	Cold shock
BZ22_RS08745	COG0747	negative chemotaxis
BZ22_RS08755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ22_RS08760	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BZ22_RS08765	COG1124	(ABC) transporter
BZ22_RS08770	COG0831	urea catabolic process
BZ22_RS08795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BZ22_RS08805	COG4413	Urea transporter
BZ22_RS08810	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BZ22_RS08825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZ22_RS08845	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ22_RS08850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ22_RS08855	COG1447	Phosphotransferase system cellobiose-specific component IIA
BZ22_RS08860	COG1917	Cupin 2, conserved barrel domain protein
BZ22_RS08860	COG2169	Transcriptional regulator
BZ22_RS08885	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BZ22_RS08890	COG0033	Phosphoglucomutase
BZ22_RS08910	COG0745	RESPONSE REGULATOR receiver
BZ22_RS08915	COG2205	protein histidine kinase activity
BZ22_RS08950	COG3272	Protein of unknown function (DUF1722)
BZ22_RS08960	COG5212	phosphodiesterase
BZ22_RS08965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BZ22_RS08970	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BZ22_RS08975	COG1984	allophanate hydrolase subunit 2
BZ22_RS09025	COG0513	Belongs to the DEAD box helicase family
BZ22_RS09035	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BZ22_RS09050	COG3026	antisigma factor binding
BZ22_RS09055	COG3086	response to oxidative stress
BZ22_RS09090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BZ22_RS09100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_RS09375	COG1737	Transcriptional regulator
BZ22_RS09385	COG0560	Phosphoserine phosphatase
BZ22_RS09415	COG2205	protein histidine kinase activity
BZ22_RS09420	COG3170	Tfp pilus assembly protein FimV
BZ22_RS09425	COG2204	response regulator
BZ22_RS09430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BZ22_RS09430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ22_RS09435	COG0347	Belongs to the P(II) protein family
BZ22_RS09440	COG2188	Transcriptional regulator
BZ22_RS09445	COG1017	nitric oxide dioxygenase activity
BZ22_RS09445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_RS09470	COG2814	Major facilitator Superfamily
BZ22_RS09475	COG3711	transcriptional antiterminator
BZ22_RS09480	COG3683	transport system, periplasmic component
BZ22_RS09485	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BZ22_RS09505	COG1104	cysteine desulfurase activity
BZ22_RS09510	COG0822	iron-sulfur transferase activity
BZ22_RS09530	COG0633	Ferredoxin
BZ22_RS09535	COG2975	iron-sulfur cluster assembly
BZ22_RS09550	COG3468	outer membrane autotransporter barrel domain protein
BZ22_RS09600	COG2976	Protein conserved in bacteria
BZ22_RS09605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ22_RS09620	COG1645	bacterial-type flagellum-dependent swarming motility
BZ22_RS09630	COG0517	IMP dehydrogenase activity
BZ22_RS09630	COG0516	GMP reductase activity
BZ22_RS09710	COG0351	phosphomethylpyrimidine kinase
BZ22_RS09730	COG0826	peptidase U32
BZ22_RS09735	COG3422	double-strand break repair
BZ22_RS09740	COG0745	RESPONSE REGULATOR receiver
BZ22_RS09745	COG2205	protein histidine kinase activity
BZ22_RS09770	COG3842	ATPase activity
BZ22_RS09780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BZ22_RS09790	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ22_RS09795	COG1177	transmembrane transport
BZ22_RS09800	COG0443	Heat shock 70 kDa protein
BZ22_RS09805	COG2239	Acts as a magnesium transporter
BZ22_RS09820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BZ22_RS09830	COG0581	inorganic phosphate transmembrane transporter activity
BZ22_RS09845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ22_RS09850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BZ22_RS09865	COG2233	PERMEase
BZ22_RS09875	COG1393	Belongs to the ArsC family
BZ22_RS09880	COG4783	chaperone-mediated protein folding
BZ22_RS09885	COG0628	permease
BZ22_RS09905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BZ22_RS09910	COG2716	regulation of RNA biosynthetic process
BZ22_RS09920	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BZ22_RS09930	COG2321	neutral zinc metallopeptidase
BZ22_RS09950	COG1876	peptidase activity
BZ22_RS09960	COG1393	Belongs to the ArsC family
BZ22_RS09975	COG1175	transmembrane transport
BZ22_RS09980	COG3842	ATPase activity
BZ22_RS09985	COG3119	arylsulfatase activity
BZ22_RS09990	COG0641	radical SAM
BZ22_RS09995	COG1988	membrane-bound metal-dependent
BZ22_RS10005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_RS10015	COG2197	response regulator
BZ22_RS10020	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_RS10020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_RS10025	COG3062	negative regulation of establishment of protein localization
BZ22_RS10035	COG3043	anaerobic respiration
BZ22_RS10040	COG3005	denitrification pathway
BZ22_RS10085	COG3111	PFAM Bacterial OB fold (BOF) protein
BZ22_RS10095	COG2837	iron assimilation
BZ22_RS10100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BZ22_RS10110	COG4886	Leucine-rich repeat (LRR) protein
BZ22_RS10120	COG2731	YhcH YjgK YiaL family protein
BZ22_RS10130	COG1737	Transcriptional regulator
BZ22_RS10140	COG4150	thiosulfate binding
BZ22_RS10145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BZ22_RS10150	COG4208	sulfate ABC transporter
BZ22_RS10160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZ22_RS10170	COG0745	RESPONSE REGULATOR receiver
BZ22_RS10175	COG5002	protein histidine kinase activity
BZ22_RS10175	COG3850	Histidine kinase
BZ22_RS10185	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZ22_RS10200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BZ22_RS10215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_RS10220	COG0745	RESPONSE REGULATOR receiver
BZ22_RS10225	COG2205	protein histidine kinase activity
BZ22_RS10240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_RS10250	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BZ22_RS10265	COG3530	Putative quorum-sensing-regulated virulence factor
BZ22_RS10315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ22_RS10330	COG0667	Aldo Keto reductase
BZ22_RS10355	COG0436	Aminotransferase
BZ22_RS10360	COG3038	cytochrome b561
BZ22_RS10390	COG3381	protein complex oligomerization
BZ22_RS10395	COG3302	dmso reductase anchor subunit
BZ22_RS10400	COG0437	4 iron, 4 sulfur cluster binding
BZ22_RS10405	COG0243	molybdopterin cofactor binding
BZ22_RS10440	COG2951	lytic endotransglycosylase activity
BZ22_RS10500	COG3121	Chaperone
BZ22_RS10505	COG3188	usher protein
BZ22_RS10585	COG2824	Alkylphosphonate utilization operon protein PhnA
BZ22_RS10595	COG1704	LemA family
BZ22_RS10615	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ22_RS10620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ22_RS10625	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ22_RS10635	COG1138	Cytochrome C-type biogenesis protein
BZ22_RS10640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZ22_RS10645	COG3088	subunit of a heme lyase
BZ22_RS10645	COG4235	cytochrome complex assembly
BZ22_RS10650	COG4235	cytochrome complex assembly
BZ22_RS10650	COG3088	subunit of a heme lyase
BZ22_RS10665	COG3691	Protein conserved in bacteria
BZ22_RS10680	COG2062	phosphohistidine phosphatase, SixA
BZ22_RS10690	COG2890	protein-(glutamine-N5) methyltransferase activity
BZ22_RS10705	COG0730	response to heat
BZ22_RS10710	COG3101	peptidyl-lysine hydroxylation
BZ22_RS10725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ22_RS10730	COG1794	racemase activity, acting on amino acids and derivatives
BZ22_RS10745	COG0697	spore germination
BZ22_RS10765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ22_RS10775	COG0586	Pfam SNARE associated Golgi protein
BZ22_RS10785	COG0285	dihydrofolate synthase activity
BZ22_RS10790	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BZ22_RS10795	COG1286	toxin biosynthetic process
BZ22_RS10800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BZ22_RS10810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_RS10815	COG4215	(ABC) transporter
BZ22_RS10820	COG4160	amino acid transport
BZ22_RS10825	COG4598	ABC transporter
BZ22_RS10830	COG1090	epimerase
BZ22_RS10840	COG0622	Phosphoesterase
BZ22_RS10845	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BZ22_RS10850	COG3037	sugar-specific permease SgaT UlaA
BZ22_RS10865	COG1609	Transcriptional regulator
BZ22_RS10870	COG0857	belongs to the CobB CobQ family
BZ22_RS10870	COG0280	phosphate acetyltransferase
BZ22_RS10895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ22_RS10900	COG0490	domain, Protein
BZ22_RS10900	COG0471	metal ion transport
BZ22_RS10915	COG0436	Aminotransferase
BZ22_RS10925	COG0583	DNA-binding transcription factor activity
BZ22_RS10935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ22_RS10955	COG1034	ATP synthesis coupled electron transport
BZ22_RS10970	COG0839	Belongs to the complex I subunit 6 family
BZ22_RS10980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BZ22_RS10985	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ22_RS11000	COG2731	YhcH YjgK YiaL family protein
BZ22_RS11005	COG3265	gluconokinase activity
BZ22_RS11010	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS11015	COG1649	PFAM Uncharacterised BCR, COG1649
BZ22_RS11020	COG1609	Transcriptional regulator
BZ22_RS11030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ22_RS11045	COG0129	dihydroxy-acid dehydratase activity
BZ22_RS11060	COG4575	ribosome binding
BZ22_RS11070	COG1169	isochorismate synthase
BZ22_RS11085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BZ22_RS11100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZ22_RS11125	COG1126	abc transporter atp-binding protein
BZ22_RS11130	COG0765	amino acid transport
BZ22_RS11135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_RS11170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZ22_RS11190	COG1063	alcohol dehydrogenase
BZ22_RS11195	COG1879	ABC-type sugar transport system periplasmic component
BZ22_RS11200	COG1129	ABC transporter
BZ22_RS11205	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS11210	COG1609	Transcriptional regulator
BZ22_RS11215	COG0583	DNA-binding transcription factor activity
BZ22_RS11220	COG0473	3-isopropylmalate dehydrogenase activity
BZ22_RS11230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ22_RS11235	COG4638	Rieske (2fe-2S)
BZ22_RS11240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_RS11245	COG2831	hemolysin activation secretion protein
BZ22_RS11250	COG3210	domain, Protein
BZ22_RS11260	COG2963	transposase activity
BZ22_RS11275	COG1476	TRANSCRIPTIONal
BZ22_RS11280	COG3210	domain, Protein
BZ22_RS11290	COG3842	ATPase activity
BZ22_RS11300	COG1609	Transcriptional regulator
BZ22_RS11315	COG0395	ABC-type sugar transport system, permease component
BZ22_RS11320	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BZ22_RS11340	COG0668	transmembrane transport
BZ22_RS11345	COG1518	maintenance of DNA repeat elements
BZ22_RS11350	COG1203	CRISPR-associated helicase, Cas3
BZ22_RS11375	COG0667	Aldo Keto reductase
BZ22_RS11385	COG0477	Major facilitator Superfamily
BZ22_RS11395	COG0583	DNA-binding transcription factor activity
BZ22_RS11400	COG2771	luxR family
BZ22_RS11405	COG3916	Acyl-homoserine-lactone synthase
BZ22_RS11430	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BZ22_RS11435	COG2943	transferase activity, transferring hexosyl groups
BZ22_RS11440	COG5645	(Lipo)protein
BZ22_RS11450	COG1560	Kdo2-lipid A biosynthetic process
BZ22_RS11475	COG0628	permease
BZ22_RS11510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BZ22_RS11515	COG1530	ribonuclease E activity
BZ22_RS11520	COG0564	pseudouridine synthase activity
BZ22_RS11535	COG1399	metal-binding, possibly nucleic acid-binding protein
BZ22_RS11540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BZ22_RS11570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ22_RS11575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ22_RS11580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BZ22_RS11590	COG0470	DNA polymerase III
BZ22_RS11595	COG0084	hydrolase, TatD family'
BZ22_RS11600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_RS11600	COG1263	PTS System
BZ22_RS11605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BZ22_RS11610	COG0537	adenosine 5'-monophosphoramidase activity
BZ22_RS11615	COG5633	Lipoprotein
BZ22_RS11640	COG1252	NADH dehydrogenase
BZ22_RS11655	COG3134	Outer membrane lipoprotein
BZ22_RS11660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BZ22_RS11665	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZ22_RS11675	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZ22_RS11695	COG2850	peptidyl-arginine hydroxylation
BZ22_RS11705	COG0745	RESPONSE REGULATOR receiver
BZ22_RS11715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BZ22_RS11735	COG1187	pseudouridine synthase activity
BZ22_RS11740	COG0538	isocitrate dehydrogenase activity
BZ22_RS11755	COG0840	transmembrane signaling receptor activity
BZ22_RS11760	COG0702	epimerase
BZ22_RS11765	COG1733	regulation of RNA biosynthetic process
BZ22_RS11790	COG1522	sequence-specific DNA binding
BZ22_RS11800	COG3321	synthase
BZ22_RS11800	COG0604	alcohol dehydrogenase
BZ22_RS11800	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS11820	COG0840	transmembrane signaling receptor activity
BZ22_RS11830	COG1285	pathogenesis
BZ22_RS11855	COG1360	Flagellar Motor Protein
BZ22_RS11860	COG0643	Histidine kinase
BZ22_RS11860	COG2198	Histidine kinase
BZ22_RS11865	COG0835	chemotaxis
BZ22_RS11880	COG0840	transmembrane signaling receptor activity
BZ22_RS11890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BZ22_RS11900	COG0745	RESPONSE REGULATOR receiver
BZ22_RS11905	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BZ22_RS11915	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ22_RS11920	COG5295	Hep Hag repeat protein
BZ22_RS11920	COG5295	Hep Hag repeat protein
BZ22_RS11920	COG5295	Hep Hag repeat protein
BZ22_RS11930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZ22_RS11975	COG3121	Chaperone
BZ22_RS11995	COG3008	intermembrane lipid transfer
BZ22_RS12000	COG2995	paraquat-inducible protein a
BZ22_RS12005	COG1956	GAF domain-containing protein
BZ22_RS12015	COG0793	Belongs to the peptidase S41A family
BZ22_RS12025	COG3539	Fimbrial protein
BZ22_RS12030	COG3121	Chaperone
BZ22_RS12045	COG3121	Chaperone
BZ22_RS12050	COG2814	Major facilitator Superfamily
BZ22_RS12055	COG0823	Involved in the tonB-independent uptake of proteins
BZ22_RS12065	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ22_RS12070	COG1823	symporter activity
BZ22_RS12075	COG1988	membrane-bound metal-dependent
BZ22_RS12080	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZ22_RS12085	COG1653	transport
BZ22_RS12090	COG3842	ATPase activity
BZ22_RS12095	COG0395	ABC-type sugar transport system, permease component
BZ22_RS12100	COG1175	transmembrane transport
BZ22_RS12110	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS12120	COG1917	Cupin 2, conserved barrel domain protein
BZ22_RS12125	COG3328	transposase activity
BZ22_RS12135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ22_RS12145	COG3001	Fructosamine kinase
BZ22_RS12155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ22_RS12160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ22_RS12165	COG1121	(ABC) transporter
BZ22_RS12170	COG0803	Belongs to the bacterial solute-binding protein 9 family
BZ22_RS12195	COG4249	Peptidase C14 caspase catalytic subunit p20
BZ22_RS12230	COG0776	regulation of translation
BZ22_RS12245	COG0386	Belongs to the glutathione peroxidase family
BZ22_RS12290	COG0791	NLP P60 protein
BZ22_RS12315	COG0574	Belongs to the PEP-utilizing enzyme family
BZ22_RS12315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ22_RS12320	COG0628	permease
BZ22_RS12325	COG0247	lactate metabolic process
BZ22_RS12325	COG0277	FAD linked oxidase domain protein
BZ22_RS12330	COG2050	protein possibly involved in aromatic compounds catabolism
BZ22_RS12340	COG0316	Belongs to the HesB IscA family
BZ22_RS12345	COG0719	Fe-S assembly protein
BZ22_RS12350	COG0396	ATPase activity
BZ22_RS12355	COG0719	Fe-S assembly protein
BZ22_RS12370	COG1388	LysM domain
BZ22_RS12370	COG1376	ErfK ybiS ycfS ynhG family protein
BZ22_RS12405	COG0307	riboflavin synthase, alpha
BZ22_RS12410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BZ22_RS12415	COG2814	Major facilitator Superfamily
BZ22_RS12420	COG0583	DNA-binding transcription factor activity
BZ22_RS12435	COG0791	NLP P60 protein
BZ22_RS12445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZ22_RS12455	COG0346	lactoylglutathione lyase activity
BZ22_RS12465	COG1902	pentaerythritol trinitrate reductase activity
BZ22_RS12470	COG1309	transcriptional regulator
BZ22_RS12475	COG2194	sulfuric ester hydrolase activity
BZ22_RS12480	COG3313	Fe-S protein
BZ22_RS12485	COG4989	oxidoreductase activity
BZ22_RS12495	COG3133	Outer membrane lipoprotein
BZ22_RS12505	COG3895	Periplasmic Protein
BZ22_RS12525	COG0625	glutathione transferase activity
BZ22_RS12540	COG3104	oligopeptide transport
BZ22_RS12545	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ22_RS12545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ22_RS12550	COG4172	Belongs to the ABC transporter superfamily
BZ22_RS12560	COG4171	peptide transport system, permease
BZ22_RS12565	COG4168	peptide transport system, permease
BZ22_RS12570	COG4166	transmembrane transport
BZ22_RS12580	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BZ22_RS12585	COG1842	Phage shock protein A
BZ22_RS12595	COG1983	PspC domain protein
BZ22_RS12605	COG3106	COG3106 Predicted ATPase
BZ22_RS12615	COG5654	RES domain protein
BZ22_RS12620	COG5642	Protein of unknown function (DUF2384)
BZ22_RS12630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BZ22_RS12635	COG4948	Mandelate Racemase Muconate Lactonizing
BZ22_RS12640	COG2866	Carboxypeptidase
BZ22_RS12645	COG4166	transmembrane transport
BZ22_RS12665	COG0657	acetylesterase activity
BZ22_RS12675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BZ22_RS12675	COG1013	pyruvate-flavodoxin oxidoreductase activity
BZ22_RS12675	COG0674	pyruvate-flavodoxin oxidoreductase activity
BZ22_RS12675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ22_RS12685	COG1285	pathogenesis
BZ22_RS12690	COG3042	response to heat
BZ22_RS12695	COG3187	Heat shock protein
BZ22_RS12700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ22_RS12705	COG2911	Protein conserved in bacteria
BZ22_RS12715	COG3784	Protein of unknown function (DUF1318)
BZ22_RS12720	COG0246	Mannitol dehydrogenase
BZ22_RS12725	COG2390	Transcriptional regulator
BZ22_RS12735	COG1643	Atp-dependent helicase
BZ22_RS12750	COG3591	Belongs to the peptidase S1B family
BZ22_RS12765	COG3038	cytochrome b561
BZ22_RS12790	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BZ22_RS12795	COG2205	protein histidine kinase activity
BZ22_RS12800	COG0745	RESPONSE REGULATOR receiver
BZ22_RS12810	COG0531	amino acid
BZ22_RS12825	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BZ22_RS12830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BZ22_RS12835	COG0589	response to stress
BZ22_RS12840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZ22_RS12845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ22_RS12865	COG1011	Hydrolase
BZ22_RS12870	COG0440	acetolactate synthase activity
BZ22_RS12875	COG0028	Belongs to the TPP enzyme family
BZ22_RS12900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BZ22_RS12905	COG1116	anion transmembrane transporter activity
BZ22_RS12910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ22_RS12925	COG1129	ABC transporter
BZ22_RS12930	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS12935	COG1879	ABC-type sugar transport system periplasmic component
BZ22_RS12945	COG1609	Transcriptional regulator
BZ22_RS12950	COG1757	Na H antiporter
BZ22_RS12955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZ22_RS12990	COG3284	Transcriptional regulator
BZ22_RS12995	COG4221	oxidoreductase activity
BZ22_RS13015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZ22_RS13020	COG1940	carbohydrate kinase activity
BZ22_RS13025	COG0583	DNA-binding transcription factor activity
BZ22_RS13030	COG2814	Major facilitator Superfamily
BZ22_RS13040	COG0114	fumarate hydratase activity
BZ22_RS13050	COG5339	Protein conserved in bacteria
BZ22_RS13055	COG2188	Transcriptional regulator
BZ22_RS13060	COG1263	PTS System
BZ22_RS13060	COG2190	(PTS) system
BZ22_RS13060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_RS13080	COG0385	Bile acid
BZ22_RS13085	COG0673	inositol 2-dehydrogenase activity
BZ22_RS13095	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS13100	COG1129	ABC transporter
BZ22_RS13105	COG1879	ABC-type sugar transport system periplasmic component
BZ22_RS13120	COG2274	protein secretion by the type I secretion system
BZ22_RS13130	COG2274	protein secretion by the type I secretion system
BZ22_RS13155	COG2207	Transcriptional regulator
BZ22_RS13155	COG3708	Transcriptional regulator
BZ22_RS13165	COG4659	FMN binding
BZ22_RS13175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BZ22_RS13180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_RS13185	COG2271	Major facilitator Superfamily
BZ22_RS13195	COG1966	Carbon starvation protein
BZ22_RS13200	COG2879	small protein
BZ22_RS13205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZ22_RS13225	COG0023	Translation Initiation Factor
BZ22_RS13240	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BZ22_RS13245	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BZ22_RS13250	COG0671	phosphoesterase, PA-phosphatase related
BZ22_RS13260	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BZ22_RS13270	COG0583	DNA-binding transcription factor activity
BZ22_RS13290	COG0616	signal peptide processing
BZ22_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS13305	COG1187	pseudouridine synthase activity
BZ22_RS13310	COG0009	L-threonylcarbamoyladenylate synthase
BZ22_RS13335	COG0512	Glutamine amidotransferase of anthranilate synthase
BZ22_RS13345	COG0134	indole-3-glycerol-phosphate synthase activity
BZ22_RS13345	COG0135	phosphoribosylanthranilate isomerase activity
BZ22_RS13365	COG3047	cAMP biosynthetic process
BZ22_RS13395	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BZ22_RS13400	COG2350	Protein conserved in bacteria
BZ22_RS13435	COG4608	Belongs to the ABC transporter superfamily
BZ22_RS13440	COG0444	Belongs to the ABC transporter superfamily
BZ22_RS13445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ22_RS13450	COG0601	transmembrane transport
BZ22_RS13460	COG2095	MarC family integral membrane protein
BZ22_RS13465	COG1454	alcohol dehydrogenase
BZ22_RS13465	COG1012	belongs to the aldehyde dehydrogenase family
BZ22_RS13485	COG0745	RESPONSE REGULATOR receiver
BZ22_RS13495	COG0788	formyltetrahydrofolate deformylase activity
BZ22_RS13510	COG0583	DNA-binding transcription factor activity
BZ22_RS13515	COG0708	Exodeoxyribonuclease III
BZ22_RS13520	COG0494	nUDIX hydrolase
BZ22_RS13530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZ22_RS13540	COG0778	Nitroreductase
BZ22_RS13545	COG0616	signal peptide processing
BZ22_RS13550	COG0252	asparaginase activity
BZ22_RS13555	COG1335	isochorismatase
BZ22_RS13560	COG3139	Protein of unknown function (DUF1315)
BZ22_RS13580	COG3713	MltA-interacting MipA family protein
BZ22_RS13585	COG2766	serine protein kinase
BZ22_RS13600	COG0583	DNA-binding transcription factor activity
BZ22_RS13610	COG2814	Major facilitator Superfamily
BZ22_RS13620	COG2719	SpoVR family
BZ22_RS13650	COG1104	cysteine desulfurase activity
BZ22_RS13665	COG0179	Fumarylacetoacetate (FAA) hydrolase
BZ22_RS13670	COG2951	lytic endotransglycosylase activity
BZ22_RS13685	COG2894	cell division
BZ22_RS13690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BZ22_RS13695	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BZ22_RS13700	COG0318	PFAM AMP-dependent synthetase and ligase
BZ22_RS13705	COG3065	identical protein binding
BZ22_RS13715	COG1199	ATP-dependent helicase activity
BZ22_RS13720	COG0251	oxidation-reduction process
BZ22_RS13735	COG0800	Aldolase
BZ22_RS13740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BZ22_RS13745	COG1737	Transcriptional regulator
BZ22_RS13750	COG0469	pyruvate kinase activity
BZ22_RS13755	COG1560	Kdo2-lipid A biosynthetic process
BZ22_RS13760	COG0739	heme binding
BZ22_RS13765	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BZ22_RS13775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ22_RS13800	COG0494	nUDIX hydrolase
BZ22_RS13810	COG1801	Protein of unknown function DUF72
BZ22_RS13815	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BZ22_RS13835	COG3102	Protein conserved in bacteria
BZ22_RS13855	COG0728	peptidoglycan biosynthetic process
BZ22_RS13860	COG0673	inositol 2-dehydrogenase activity
BZ22_RS13870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ22_RS13885	COG3381	protein complex oligomerization
BZ22_RS13900	COG1940	carbohydrate kinase activity
BZ22_RS13905	COG0584	glycerophosphoryl diester phosphodiesterase
BZ22_RS13915	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ22_RS13920	COG3833	ABC-type maltose transport systems, permease component
BZ22_RS13945	COG0659	secondary active sulfate transmembrane transporter activity
BZ22_RS13965	COG2890	protein-(glutamine-N5) methyltransferase activity
BZ22_RS13995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZ22_RS14015	COG0012	GTP binding
BZ22_RS14045	COG5002	protein histidine kinase activity
BZ22_RS14085	COG0500	methyltransferase
BZ22_RS14150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_RS14155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BZ22_RS14170	COG0402	S-adenosylhomocysteine deaminase activity
BZ22_RS14225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ22_RS14230	COG3850	Histidine kinase
BZ22_RS14235	COG0387	Pfam Sodium calcium exchanger
BZ22_RS14245	COG1702	phosphate starvation-inducible protein PhoH
BZ22_RS14260	COG3658	cytochrome
BZ22_RS14265	COG1215	transferase activity, transferring glycosyl groups
BZ22_RS14270	COG0726	polysaccharide deacetylase
BZ22_RS14270	COG1649	PFAM Uncharacterised BCR, COG1649
BZ22_RS14275	COG0457	Tetratricopeptide repeat
BZ22_RS14280	COG0006	proline dipeptidase activity
BZ22_RS14300	COG0577	efflux transmembrane transporter activity
BZ22_RS14300	COG1136	(ABC) transporter
BZ22_RS14310	COG1136	(ABC) transporter
BZ22_RS14310	COG0577	efflux transmembrane transporter activity
BZ22_RS14325	COG0672	)-iron permease
BZ22_RS14335	COG2066	Belongs to the glutaminase family
BZ22_RS14340	COG1349	DNA-binding transcription factor activity
BZ22_RS14350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ22_RS14355	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ22_RS14395	COG2030	dehydratase
BZ22_RS14400	COG0427	acetyl-CoA hydrolase
BZ22_RS14430	COG3188	usher protein
BZ22_RS14440	COG3121	Chaperone
BZ22_RS14455	COG3842	ATPase activity
BZ22_RS14460	COG0395	ABC-type sugar transport system, permease component
BZ22_RS14465	COG1175	transmembrane transport
BZ22_RS14475	COG0673	inositol 2-dehydrogenase activity
BZ22_RS14485	COG2188	Transcriptional regulator
BZ22_RS14595	COG4974	Belongs to the 'phage' integrase family
BZ22_RS14650	COG2176	DNA-directed DNA polymerase activity
BZ22_RS14650	COG5002	protein histidine kinase activity
BZ22_RS14680	COG4695	Portal protein
BZ22_RS14850	COG2197	response regulator
BZ22_RS14860	COG3136	membrane protein required for alginate biosynthesis
BZ22_RS14880	COG1113	amino acid transport
BZ22_RS14900	COG2822	iron ion transport
BZ22_RS14905	COG0672	)-iron permease
BZ22_RS14920	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZ22_RS14920	COG0506	proline dehydrogenase activity
BZ22_RS14920	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZ22_RS14935	COG1126	abc transporter atp-binding protein
BZ22_RS14940	COG0765	amino acid transport
BZ22_RS14945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_RS14960	COG1191	sigma factor activity
BZ22_RS14995	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BZ22_RS15000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BZ22_RS15015	COG1677	Flagellar hook-basal body complex protein FliE
BZ22_RS15035	COG1157	protein secretion by the type III secretion system
BZ22_RS15050	COG1580	Controls the rotational direction of flagella during chemotaxis
BZ22_RS15075	COG1987	bacterial-type flagellum assembly
BZ22_RS15090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_RS15095	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS15100	COG1129	ABC transporter
BZ22_RS15110	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS15115	COG3347	Dehydrogenase
BZ22_RS15115	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS15120	COG2390	Transcriptional regulator
BZ22_RS15130	COG1256	bacterial-type flagellum assembly
BZ22_RS15170	COG1558	bacterial-type flagellum-dependent cell motility
BZ22_RS15175	COG1815	bacterial-type flagellum-dependent cell motility
BZ22_RS15185	COG2747	anti-sigma28 factor FlgM
BZ22_RS15190	COG3418	PFAM FlgN family protein
BZ22_RS15210	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ22_RS15215	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ22_RS15245	COG2372	response to copper ion
BZ22_RS15250	COG1528	Iron-storage protein
BZ22_RS15265	COG1770	oligopeptidase
BZ22_RS15280	COG3141	response to X-ray
BZ22_RS15285	COG0513	Belongs to the DEAD box helicase family
BZ22_RS15310	COG1760	l-serine dehydratase
BZ22_RS15315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BZ22_RS15320	COG2368	4-hydroxyphenylacetate
BZ22_RS15335	COG3971	2-oxopent-4-enoate hydratase activity
BZ22_RS15345	COG3384	dioxygenase
BZ22_RS15350	COG1012	belongs to the aldehyde dehydrogenase family
BZ22_RS15365	COG1846	Transcriptional regulator
BZ22_RS15370	COG1253	flavin adenine dinucleotide binding
BZ22_RS15375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_RS15375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_RS15380	COG3715	PTS system
BZ22_RS15385	COG3716	PTS system mannose fructose sorbose family IID component
BZ22_RS15405	COG5001	Diguanylate cyclase
BZ22_RS15405	COG5002	protein histidine kinase activity
BZ22_RS15405	COG3447	MASE1 domain protein
BZ22_RS15415	COG2226	methyltransferase
BZ22_RS15420	COG1496	oxidoreductase activity
BZ22_RS15445	COG1113	amino acid transport
BZ22_RS15480	COG2207	Transcriptional regulator
BZ22_RS15490	COG1132	(ABC) transporter
BZ22_RS15520	COG2223	nitrite transmembrane transporter activity
BZ22_RS15540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BZ22_RS15565	COG3122	Protein conserved in bacteria
BZ22_RS15585	COG0534	Mate efflux family protein
BZ22_RS15600	COG4948	Mandelate Racemase Muconate Lactonizing
BZ22_RS15610	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS15615	COG3011	Protein conserved in bacteria
BZ22_RS15620	COG2271	Major facilitator Superfamily
BZ22_RS15625	COG1388	LysM domain
BZ22_RS15625	COG1470	cell adhesion involved in biofilm formation
BZ22_RS15640	COG2925	Exonuclease
BZ22_RS15645	COG0531	amino acid
BZ22_RS15655	COG0371	Dehydrogenase
BZ22_RS15660	COG1129	ABC transporter
BZ22_RS15665	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS15680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_RS15690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BZ22_RS15720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BZ22_RS15720	COG0140	phosphoribosyl-ATP diphosphatase activity
BZ22_RS15740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZ22_RS15745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZ22_RS15750	COG4264	IucA IucC family
BZ22_RS15760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ22_RS15765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_RS15770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_RS15775	COG1120	ATPase activity
BZ22_RS15790	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BZ22_RS15795	COG0076	glutamate decarboxylase activity
BZ22_RS15800	COG4114	ferric iron reductase
BZ22_RS15805	COG1253	flavin adenine dinucleotide binding
BZ22_RS15810	COG2982	Protein involved in outer membrane biogenesis
BZ22_RS15825	COG0489	protein tyrosine kinase activity
BZ22_RS15850	COG2814	Major facilitator Superfamily
BZ22_RS15860	COG1346	cytolysis
BZ22_RS15875	COG2949	membrane
BZ22_RS15880	COG4211	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS15895	COG2311	Membrane
BZ22_RS15905	COG0477	Major facilitator Superfamily
BZ22_RS15910	COG0583	DNA-binding transcription factor activity
BZ22_RS15945	COG1136	(ABC) transporter
BZ22_RS15955	COG0303	'Molybdopterin
BZ22_RS15970	COG0488	(ABC) transporter
BZ22_RS16070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BZ22_RS16075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BZ22_RS16085	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS16090	COG1024	Enoyl-CoA hydratase
BZ22_RS16100	COG3425	synthase
BZ22_RS16105	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS16110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ22_RS16115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BZ22_RS16125	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS16150	COG2920	part of a sulfur-relay system
BZ22_RS16170	COG1832	CoA-binding protein
BZ22_RS16185	COG0210	DNA helicase
BZ22_RS16190	COG3304	Inner membrane component domain
BZ22_RS16195	COG1289	transmembrane transporter activity
BZ22_RS16200	COG3070	regulator of competence-specific genes
BZ22_RS16230	COG1067	ATP-dependent peptidase activity
BZ22_RS16245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ22_RS16250	COG3130	regulation of translation
BZ22_RS16260	COG3009	Protein conserved in bacteria
BZ22_RS16265	COG3008	intermembrane lipid transfer
BZ22_RS16265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZ22_RS16270	COG2995	paraquat-inducible protein a
BZ22_RS16275	COG0488	(ABC) transporter
BZ22_RS16285	COG3217	Mosc domain protein beta barrel domain protein
BZ22_RS16285	COG0633	Ferredoxin
BZ22_RS16300	COG0308	aminopeptidase N
BZ22_RS16320	COG1448	Aminotransferase
BZ22_RS16325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ22_RS16330	COG3108	Peptidase M15
BZ22_RS16335	COG2989	Protein conserved in bacteria
BZ22_RS16355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BZ22_RS16365	COG3173	Aminoglycoside phosphotransferase
BZ22_RS16380	COG1278	Cold shock
BZ22_RS16390	COG5383	Protein conserved in bacteria
BZ22_RS16405	COG2333	competence protein COMEC
BZ22_RS16405	COG0658	competence protein
BZ22_RS16415	COG0539	negative regulation of cytoplasmic translation
BZ22_RS16445	COG0252	asparaginase activity
BZ22_RS16450	COG1944	ATP diphosphatase activity
BZ22_RS16455	COG2116	formate transmembrane transporter activity
BZ22_RS16460	COG1882	Formate acetyltransferase
BZ22_RS16470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BZ22_RS16485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZ22_RS16495	COG3107	peptidoglycan biosynthetic process
BZ22_RS16495	COG1674	ftsk spoiiie
BZ22_RS16505	COG0492	ferredoxin-NADP+ reductase activity
BZ22_RS16520	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BZ22_RS16530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BZ22_RS16535	COG0542	response to heat
BZ22_RS16545	COG1278	Cold shock
BZ22_RS16555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_RS16560	COG2990	Protein conserved in bacteria
BZ22_RS16565	COG3593	DNA synthesis involved in DNA repair
BZ22_RS16570	COG2431	L-lysine efflux transmembrane transporter activity
BZ22_RS16580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_RS16585	COG0028	Belongs to the TPP enzyme family
BZ22_RS16590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BZ22_RS16595	COG0702	epimerase
BZ22_RS16600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_RS16610	COG1605	Chorismate mutase
BZ22_RS16615	COG1126	abc transporter atp-binding protein
BZ22_RS16620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_RS16625	COG4215	(ABC) transporter
BZ22_RS16630	COG4160	amino acid transport
BZ22_RS16655	COG1120	ATPase activity
BZ22_RS16660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_RS16685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_RS16700	COG1177	transmembrane transport
BZ22_RS16705	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ22_RS16710	COG3842	ATPase activity
BZ22_RS16715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BZ22_RS16750	COG0671	phosphoesterase, PA-phosphatase related
BZ22_RS16760	COG1349	DNA-binding transcription factor activity
BZ22_RS16765	COG0814	amino acid
BZ22_RS16775	COG1686	Belongs to the peptidase S11 family
BZ22_RS16780	COG2011	ABC-type metal ion transport system permease component
BZ22_RS16805	COG0625	glutathione transferase activity
BZ22_RS16810	COG4771	TonB-dependent receptor
BZ22_RS16820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_RS16830	COG0833	amino acid
BZ22_RS16835	COG0583	DNA-binding transcription factor activity
BZ22_RS16840	COG2855	membrane
BZ22_RS16850	COG3188	usher protein
BZ22_RS16855	COG3121	Chaperone
BZ22_RS16870	COG3710	Transcriptional regulator
BZ22_RS16875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_RS16875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_RS16875	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BZ22_RS16880	COG1105	Belongs to the carbohydrate kinase PfkB family
BZ22_RS16890	COG0494	nUDIX hydrolase
BZ22_RS16900	COG1129	ABC transporter
BZ22_RS16935	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS16960	COG0246	Mannitol dehydrogenase
BZ22_RS16965	COG2186	Transcriptional regulator
BZ22_RS16975	COG0523	cobalamin synthesis protein
BZ22_RS16980	COG0671	phosphoesterase, PA-phosphatase related
BZ22_RS16985	COG0791	NLP P60 protein
BZ22_RS16990	COG2200	EAL domain
BZ22_RS16995	COG4166	transmembrane transport
BZ22_RS17000	COG4174	ABC transporter (Permease)
BZ22_RS17005	COG4239	(ABC) transporter, permease
BZ22_RS17010	COG4172	Belongs to the ABC transporter superfamily
BZ22_RS17020	COG2814	Major facilitator Superfamily
BZ22_RS17025	COG1187	pseudouridine synthase activity
BZ22_RS17030	COG1061	Type III restriction enzyme res subunit
BZ22_RS17045	COG3082	Protein of unknown function (DUF1414)
BZ22_RS17050	COG3083	sulfuric ester hydrolase activity
BZ22_RS17065	COG3157	Type VI secretion system effector, Hcp
BZ22_RS17090	COG2723	6-phospho-beta-galactosidase activity
BZ22_RS17095	COG1737	Transcriptional regulator
BZ22_RS17120	COG3299	homolog of phage Mu protein gp47
BZ22_RS17160	COG4386	tail sheath protein
BZ22_RS17180	COG3622	Belongs to the hyi family
BZ22_RS17185	COG1349	DNA-binding transcription factor activity
BZ22_RS17190	COG0235	Class ii aldolase
BZ22_RS17195	COG3395	kinase activity
BZ22_RS17240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BZ22_RS17275	COG2223	nitrite transmembrane transporter activity
BZ22_RS17280	COG2198	Histidine kinase
BZ22_RS17280	COG0642	Histidine kinase
BZ22_RS17290	COG2205	protein histidine kinase activity
BZ22_RS17290	COG0784	Response regulator, receiver
BZ22_RS17320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_RS17335	COG0814	amino acid
BZ22_RS17360	COG0697	spore germination
BZ22_RS17370	COG1982	Orn Lys Arg decarboxylase major
BZ22_RS17375	COG0531	amino acid
BZ22_RS17380	COG1174	glycine betaine transport
BZ22_RS17385	COG1125	glycine betaine transport
BZ22_RS17390	COG1174	glycine betaine transport
BZ22_RS17395	COG1732	Glycine betaine
BZ22_RS17400	COG2897	thiosulfate sulfurtransferase activity
BZ22_RS17420	COG1122	ATPase activity
BZ22_RS17440	COG4807	Protein conserved in bacteria
BZ22_RS17455	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BZ22_RS17465	COG2261	transglycosylase associated protein
BZ22_RS17485	COG0277	FAD linked oxidase domain protein
BZ22_RS17490	COG1686	Belongs to the peptidase S11 family
BZ22_RS17500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ22_RS17520	COG0513	Belongs to the DEAD box helicase family
BZ22_RS17560	COG0513	Belongs to the DEAD box helicase family
BZ22_RS17565	COG1309	transcriptional regulator
BZ22_RS17575	COG1131	(ABC) transporter
BZ22_RS17580	COG0842	Transport permease protein
BZ22_RS17585	COG0842	Transport permease protein
BZ22_RS17605	COG1902	pentaerythritol trinitrate reductase activity
BZ22_RS17625	COG2211	Major facilitator Superfamily
BZ22_RS17630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BZ22_RS17640	COG0583	DNA-binding transcription factor activity
BZ22_RS17645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ22_RS17665	COG0670	Belongs to the BI1 family
BZ22_RS17670	COG0314	molybdopterin synthase activity
BZ22_RS17675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BZ22_RS17685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BZ22_RS17695	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BZ22_RS17700	COG4628	conserved protein (DUF2132)
BZ22_RS17710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BZ22_RS17720	COG2226	methyltransferase
BZ22_RS17745	COG0561	phosphatase activity
BZ22_RS17755	COG4149	molybdate abc transporter
BZ22_RS17760	COG0725	ABC transporter, periplasmic molybdate-binding protein
BZ22_RS17770	COG2005	Transcriptional regulator
BZ22_RS17770	COG3585	molybdate ion transport
BZ22_RS17775	COG1119	ATPase activity
BZ22_RS17790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BZ22_RS17795	COG1085	galactose-1-phosphate uridylyltransferase
BZ22_RS17805	COG2017	converts alpha-aldose to the beta-anomer
BZ22_RS17820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZ22_RS17825	COG1230	cation diffusion facilitator family transporter
BZ22_RS17865	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BZ22_RS17870	COG2885	chlorophyll binding
BZ22_RS17880	COG3064	Membrane
BZ22_RS17880	COG3064	Membrane
BZ22_RS17885	COG0848	biopolymer transport protein
BZ22_RS17890	COG0811	peptide transport
BZ22_RS17895	COG0824	Thioesterase
BZ22_RS17900	COG3790	cyd operon protein YbgE
BZ22_RS17905	COG4890	Cyd operon protein YbgT
BZ22_RS17910	COG1294	oxidase, subunit
BZ22_RS17915	COG1271	oxidase subunit
BZ22_RS17920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZ22_RS17930	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ22_RS17935	COG0567	Dehydrogenase, E1 component
BZ22_RS17945	COG1053	succinate dehydrogenase
BZ22_RS17950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BZ22_RS17955	COG2009	succinate dehydrogenase
BZ22_RS17970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BZ22_RS17975	COG0497	DNA recombination
BZ22_RS17980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ22_RS17990	COG2867	negative regulation of translational initiation
BZ22_RS18000	COG0582	viral genome integration into host DNA
BZ22_RS18005	COG2963	transposase activity
BZ22_RS18010	COG0582	viral genome integration into host DNA
BZ22_RS18020	COG0596	Alpha beta hydrolase
BZ22_RS18040	COG0735	belongs to the Fur family
BZ22_RS18065	COG2190	(PTS) system
BZ22_RS18065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_RS18065	COG1263	PTS System
BZ22_RS18075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BZ22_RS18080	COG1940	carbohydrate kinase activity
BZ22_RS18080	COG1846	Transcriptional regulator
BZ22_RS18085	COG0647	UMP catabolic process
BZ22_RS18090	COG0367	asparagine synthase
BZ22_RS18130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ22_RS18140	COG1702	phosphate starvation-inducible protein PhoH
BZ22_RS18150	COG4535	Mg2 and Co2 transporter CorC
BZ22_RS18155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BZ22_RS18165	COG0765	amino acid transport
BZ22_RS18170	COG0765	amino acid transport
BZ22_RS18175	COG1126	abc transporter atp-binding protein
BZ22_RS18180	COG2888	peptidyl-tyrosine sulfation
BZ22_RS18195	COG1466	dna polymerase III delta subunit
BZ22_RS18205	COG0799	negative regulation of ribosome biogenesis
BZ22_RS18215	COG0768	penicillin binding
BZ22_RS18220	COG0772	Belongs to the SEDS family
BZ22_RS18225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ22_RS18230	COG1686	Belongs to the peptidase S11 family
BZ22_RS18250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZ22_RS18270	COG1278	Cold shock
BZ22_RS18275	COG2197	response regulator
BZ22_RS18300	COG5265	(ABC) transporter
BZ22_RS18310	COG3718	enzyme involved in inositol metabolism
BZ22_RS18320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_RS18325	COG0673	inositol 2-dehydrogenase activity
BZ22_RS18330	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS18335	COG1129	ABC transporter
BZ22_RS18345	COG0673	inositol 2-dehydrogenase activity
BZ22_RS18350	COG3962	Belongs to the TPP enzyme family
BZ22_RS18365	COG2373	Large extracellular alpha-helical protein
BZ22_RS18370	COG4953	penicillin-binding protein 1C
BZ22_RS18375	COG3423	Transcriptional regulator
BZ22_RS18420	COG2850	peptidyl-arginine hydroxylation
BZ22_RS18430	COG3328	transposase activity
BZ22_RS18435	COG1187	pseudouridine synthase activity
BZ22_RS18450	COG1472	Belongs to the glycosyl hydrolase 3 family
BZ22_RS18470	COG0656	L-ascorbic acid biosynthetic process
BZ22_RS18475	COG0667	Aldo Keto reductase
BZ22_RS18495	COG2453	phosphatase
BZ22_RS18495	COG0671	phosphoesterase, PA-phosphatase related
BZ22_RS18500	COG2267	carboxylic ester hydrolase activity
BZ22_RS18510	COG4589	Belongs to the CDS family
BZ22_RS18515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BZ22_RS18715	COG4386	tail sheath protein
BZ22_RS18745	COG0582	viral genome integration into host DNA
BZ22_RS18770	COG2003	Belongs to the UPF0758 family
BZ22_RS18790	COG3596	GTP binding
BZ22_RS18845	COG0582	viral genome integration into host DNA
BZ22_RS18860	COG2501	S4 domain
BZ22_RS18870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ22_RS18880	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BZ22_RS18885	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BZ22_RS18890	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BZ22_RS18895	COG4181	ATPase activity
BZ22_RS18900	COG2755	lipolytic protein G-D-S-L family
BZ22_RS18905	COG0300	oxidoreductase activity
BZ22_RS18910	COG3118	belongs to the thioredoxin family
BZ22_RS18915	COG0330	HflC and HflK could
BZ22_RS18920	COG1585	Membrane protein implicated in regulation of membrane protease activity
BZ22_RS18925	COG0789	Transcriptional regulator
BZ22_RS18930	COG2217	Heavy metal translocating P-type atpase
BZ22_RS18935	COG3735	TraB family
BZ22_RS18940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BZ22_RS18960	COG2223	nitrite transmembrane transporter activity
BZ22_RS18970	COG2223	nitrite transmembrane transporter activity
BZ22_RS18975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZ22_RS18975	COG4651	solute:proton antiporter activity
BZ22_RS18980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_RS18985	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZ22_RS18995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_RS19010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_RS19015	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BZ22_RS19030	COG2244	polysaccharide biosynthetic process
BZ22_RS19040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_RS19060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_RS19060	COG0543	2 iron, 2 sulfur cluster binding
BZ22_RS19090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BZ22_RS19115	COG3264	Mechanosensitive ion channel
BZ22_RS19115	COG1196	nuclear chromosome segregation
BZ22_RS19120	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BZ22_RS19125	COG1309	transcriptional regulator
BZ22_RS19130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_RS19135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_RS19150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ22_RS19170	COG3695	enzyme binding
BZ22_RS19175	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BZ22_RS19180	COG1946	Acyl-CoA thioesterase
BZ22_RS19185	COG0004	ammonium transporteR
BZ22_RS19190	COG0347	Belongs to the P(II) protein family
BZ22_RS19195	COG1132	(ABC) transporter
BZ22_RS19200	COG1132	(ABC) transporter
BZ22_RS19205	COG1522	sequence-specific DNA binding
BZ22_RS19220	COG4533	DNA binding
BZ22_RS19230	COG0824	Thioesterase
BZ22_RS19235	COG1555	photosystem II stabilization
BZ22_RS19240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ22_RS19245	COG0776	regulation of translation
BZ22_RS19250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZ22_RS19275	COG0271	Belongs to the BolA IbaG family
BZ22_RS19280	COG3056	Lipoprotein
BZ22_RS19285	COG2223	nitrite transmembrane transporter activity
BZ22_RS19295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BZ22_RS19300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BZ22_RS19305	COG1845	cytochrome c oxidase, subunit III
BZ22_RS19310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BZ22_RS19320	COG2814	Major facilitator Superfamily
BZ22_RS19330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BZ22_RS19335	COG0693	protein deglycase activity
BZ22_RS19355	COG0142	geranyltranstransferase activity
BZ22_RS19365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BZ22_RS19370	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BZ22_RS19385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ22_RS19385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ22_RS19405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZ22_RS19410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZ22_RS19415	COG1862	Preprotein translocase
BZ22_RS19435	COG0450	alkyl hydroperoxide reductase
BZ22_RS19450	COG0300	oxidoreductase activity
BZ22_RS19455	COG0366	Alpha amylase catalytic
BZ22_RS19475	COG5002	protein histidine kinase activity
BZ22_RS19480	COG0745	RESPONSE REGULATOR receiver
BZ22_RS19490	COG0420	3'-5' exonuclease activity
BZ22_RS19495	COG0419	ATPase involved in DNA repair
BZ22_RS19500	COG1940	carbohydrate kinase activity
BZ22_RS19535	COG2226	methyltransferase
BZ22_RS19595	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ22_RS19615	COG1477	protein flavinylation
BZ22_RS19635	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ22_RS19640	COG1805	sodium ion transport
BZ22_RS19650	COG3034	peptidoglycan biosynthetic process
BZ22_RS19655	COG0121	glutamine amidotransferase
BZ22_RS19665	COG1960	acyl-CoA dehydrogenase activity
BZ22_RS19675	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BZ22_RS19725	COG0436	Aminotransferase
BZ22_RS19740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BZ22_RS19750	COG0765	amino acid transport
BZ22_RS19790	COG2814	Major facilitator Superfamily
BZ22_RS19795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BZ22_RS19805	COG1846	Transcriptional regulator
BZ22_RS19810	COG1566	PFAM secretion protein HlyD family protein
BZ22_RS19815	COG2814	Major facilitator Superfamily
BZ22_RS19820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ22_RS19825	COG3118	belongs to the thioredoxin family
BZ22_RS19835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ22_RS19835	COG0045	succinate-CoA ligase (ADP-forming) activity
BZ22_RS19835	COG1042	CoA-binding domain protein
BZ22_RS19840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZ22_RS19845	COG5544	Lipoprotein
BZ22_RS19885	COG0542	response to heat
BZ22_RS19895	COG0564	pseudouridine synthase activity
BZ22_RS19900	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ22_RS19905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BZ22_RS19910	COG0077	Prephenate dehydratase
BZ22_RS19910	COG1605	Chorismate mutase
BZ22_RS19915	COG0287	Prephenate dehydrogenase
BZ22_RS19915	COG1605	Chorismate mutase
BZ22_RS19920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZ22_RS19925	COG3279	Response regulator of the LytR AlgR family
BZ22_RS19930	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ22_RS19935	COG3137	Salt-induced outer membrane protein
BZ22_RS19960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BZ22_RS19965	COG4137	Cytochrome C assembly protein
BZ22_RS19970	COG4536	flavin adenine dinucleotide binding
BZ22_RS19985	COG1238	metal cluster binding
BZ22_RS19990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ22_RS20015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BZ22_RS20055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZ22_RS20060	COG3958	Transketolase
BZ22_RS20065	COG3959	Transketolase, thiamine diphosphate binding domain
BZ22_RS20070	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS20075	COG1129	ABC transporter
BZ22_RS20085	COG1879	ABC-type sugar transport system periplasmic component
BZ22_RS20095	COG3783	Cytochrome b(562)
BZ22_RS20100	COG3038	cytochrome b561
BZ22_RS20105	COG3381	protein complex oligomerization
BZ22_RS20110	COG3302	dmso reductase anchor subunit
BZ22_RS20115	COG0437	4 iron, 4 sulfur cluster binding
BZ22_RS20120	COG0243	molybdopterin cofactor binding
BZ22_RS20125	COG0235	Class ii aldolase
BZ22_RS20130	COG1349	DNA-binding transcription factor activity
BZ22_RS20140	COG1129	ABC transporter
BZ22_RS20145	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS20150	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_RS20155	COG3623	hexulose-6-phosphate isomerase
BZ22_RS20160	COG1070	Carbohydrate kinase
BZ22_RS20165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BZ22_RS20165	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BZ22_RS20175	COG0024	Methionine aminopeptidase
BZ22_RS20190	COG4771	TonB-dependent receptor
BZ22_RS20200	COG1858	cytochrome C peroxidase
BZ22_RS20205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_RS20225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BZ22_RS20240	COG2376	Dihydroxyacetone kinase
BZ22_RS20245	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_RS20250	COG1063	alcohol dehydrogenase
BZ22_RS20255	COG0698	ribose 5-phosphate isomerase
BZ22_RS20270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZ22_RS20275	COG1388	LysM domain
BZ22_RS20275	COG4942	peptidase
BZ22_RS20315	COG0529	Catalyzes the synthesis of activated sulfate
BZ22_RS20365	COG0720	synthase
BZ22_RS20370	COG0602	queuosine metabolic process
BZ22_RS20390	COG3956	TIGRFAM MazG family protein
BZ22_RS20400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZ22_RS20405	COG4999	Histidine kinase
BZ22_RS20405	COG3850	Histidine kinase
BZ22_RS20405	COG3437	response regulator, receiver
BZ22_RS20405	COG2205	protein histidine kinase activity
BZ22_RS20410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ22_RS20430	COG2860	membrane
BZ22_RS20450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_RS20455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ22_RS20460	COG1120	ATPase activity
BZ22_RS20465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BZ22_RS20470	COG1643	Atp-dependent helicase
BZ22_RS20475	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BZ22_RS20495	COG0617	tRNA 3'-terminal CCA addition
BZ22_RS20500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BZ22_RS20520	COG0726	polysaccharide deacetylase
BZ22_RS20525	COG0842	Transport permease protein
BZ22_RS20530	COG1131	(ABC) transporter
BZ22_RS20535	COG0288	reversible hydration of carbon dioxide
BZ22_RS20540	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BZ22_RS20545	COG2132	Multicopper oxidase
BZ22_RS20565	COG0697	spore germination
BZ22_RS20575	COG1049	propionate catabolic process, 2-methylcitrate cycle
BZ22_RS20590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ22_RS20595	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ22_RS20600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BZ22_RS20605	COG2186	Transcriptional regulator
BZ22_RS20610	COG1113	amino acid transport
BZ22_RS20615	COG3725	Membrane protein required for beta-lactamase induction
BZ22_RS20620	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ22_RS20630	COG4969	Belongs to the N-Me-Phe pilin family
BZ22_RS20635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BZ22_RS20640	COG1459	type II secretion system
BZ22_RS20680	COG0494	nUDIX hydrolase
BZ22_RS20705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BZ22_RS20710	COG0849	cell division
BZ22_RS20715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BZ22_RS20735	COG0772	Belongs to the SEDS family
BZ22_RS20750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BZ22_RS20755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BZ22_RS20760	COG0768	penicillin binding
BZ22_RS20765	COG3116	cell division
BZ22_RS20785	COG1609	Transcriptional regulator
BZ22_RS20800	COG0028	Belongs to the TPP enzyme family
BZ22_RS20810	COG1022	Amp-dependent synthetase and ligase
BZ22_RS20835	COG0473	3-isopropylmalate dehydrogenase activity
BZ22_RS20850	COG2814	Major facilitator Superfamily
BZ22_RS20870	COG4143	(ABC) transporter
BZ22_RS20875	COG1178	ABC-type Fe3 transport system permease component
BZ22_RS20880	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BZ22_RS20885	COG0586	Pfam SNARE associated Golgi protein
BZ22_RS20890	COG0417	DNA replication proofreading
BZ22_RS20910	COG2885	chlorophyll binding
BZ22_RS20910	COG3047	cAMP biosynthetic process
BZ22_RS20995	COG0564	pseudouridine synthase activity
BZ22_RS21045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BZ22_RS21055	COG2966	Psort location CytoplasmicMembrane, score
BZ22_RS21065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BZ22_RS21085	COG1047	Peptidyl-prolyl cis-trans
BZ22_RS21100	COG0196	riboflavin kinase activity
BZ22_RS21115	COG0583	DNA-binding transcription factor activity
BZ22_RS21135	COG1584	GPR1 FUN34 yaaH family protein
BZ22_RS21150	COG0521	Mo-molybdopterin cofactor biosynthetic process
BZ22_RS21180	COG0745	RESPONSE REGULATOR receiver
BZ22_RS21185	COG3045	CreA protein
BZ22_RS21190	COG3708	Transcriptional regulator
BZ22_RS21190	COG2207	Transcriptional regulator
BZ22_RS21205	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BZ22_RS21210	COG0741	lytic transglycosylase activity
BZ22_RS21225	COG2199	diguanylate cyclase activity
BZ22_RS21230	COG2885	chlorophyll binding
BZ22_RS21235	COG0488	(ABC) transporter
BZ22_RS21255	COG0560	Phosphoserine phosphatase
BZ22_RS21260	COG3726	membrane protein affecting hemolysin expression
BZ22_RS21285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ22_RS21290	COG0084	hydrolase, TatD family'
BZ22_RS21295	COG4667	esterase of the alpha-beta hydrolase superfamily
BZ22_RS21305	COG2823	Periplasmic or secreted lipoprotein
BZ22_RS21315	COG0456	acetyltransferase
BZ22_RS21320	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BZ22_RS21375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_RS21380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_RS21400	COG0859	PFAM glycosyl transferase family 9
BZ22_RS21410	COG2390	Transcriptional regulator
BZ22_RS21455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_RS21455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_RS21455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ22_RS21515	COG3210	domain, Protein
BZ22_RS21520	COG3210	domain, Protein