locus-tag	class	description
LGL93_RS00010	COG0592	DNA-directed DNA polymerase activity
LGL93_RS00020	COG0187	DNA topoisomerase II activity
LGL93_RS00025	COG0561	phosphatase activity
LGL93_RS00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL93_RS00035	COG5645	(Lipo)protein
LGL93_RS00050	COG0569	domain protein
LGL93_RS00050	COG2985	domain, Protein
LGL93_RS00055	COG3977	Valine--pyruvate aminotransferase
LGL93_RS00060	COG2885	chlorophyll binding
LGL93_RS00080	COG2818	Glycosylase
LGL93_RS00130	COG2213	PTS system mannitol-specific
LGL93_RS00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL93_RS00140	COG3722	fumarate hydratase activity
LGL93_RS00150	COG2258	MOSC domain
LGL93_RS00155	COG0840	transmembrane signaling receptor activity
LGL93_RS00160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL93_RS00175	COG0437	4 iron, 4 sulfur cluster binding
LGL93_RS00180	COG2864	formate dehydrogenase
LGL93_RS00190	COG1921	L-seryl-tRNASec selenium transferase activity
LGL93_RS00195	COG3276	selenocysteine insertion sequence binding
LGL93_RS00200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL93_RS00210	COG3274	enterobacterial common antigen metabolic process
LGL93_RS00250	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL93_RS00255	COG2986	histidine ammonia-lyase
LGL93_RS00275	COG2194	sulfuric ester hydrolase activity
LGL93_RS00280	COG2197	response regulator
LGL93_RS00285	COG3851	Histidine kinase
LGL93_RS00290	COG2271	Major facilitator Superfamily
LGL93_RS00300	COG0747	negative chemotaxis
LGL93_RS00305	COG0601	transmembrane transport
LGL93_RS00310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL93_RS00315	COG0444	Belongs to the ABC transporter superfamily
LGL93_RS00320	COG4608	Belongs to the ABC transporter superfamily
LGL93_RS00325	COG2194	sulfuric ester hydrolase activity
LGL93_RS00350	COG1215	transferase activity, transferring glycosyl groups
LGL93_RS00360	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL93_RS00365	COG0457	Tetratricopeptide repeat
LGL93_RS00365	COG3118	belongs to the thioredoxin family
LGL93_RS00370	COG2200	EAL domain
LGL93_RS00370	COG2199	diguanylate cyclase activity
LGL93_RS00375	COG1301	dicarboxylic acid transport
LGL93_RS00380	COG0612	Peptidase, M16
LGL93_RS00385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL93_RS00390	COG1942	4-Oxalocrotonate Tautomerase
LGL93_RS00395	COG2200	EAL domain
LGL93_RS00400	COG2134	cdp-diacylglycerol pyrophosphatase
LGL93_RS00405	COG1295	ribonuclease BN
LGL93_RS00415	COG1301	dicarboxylic acid transport
LGL93_RS00420	COG0626	cystathionine gamma-synthase activity
LGL93_RS00430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL93_RS00435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL93_RS00440	COG0339	signal peptide processing
LGL93_RS00445	COG0742	ribosomal rna small subunit methyltransferase
LGL93_RS00455	COG0589	response to stress
LGL93_RS00465	COG0306	phosphate transporter
LGL93_RS00470	COG2081	HI0933 family
LGL93_RS00515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL93_RS00635	COG1247	-acetyltransferase
LGL93_RS00645	COG1741	Belongs to the pirin family
LGL93_RS00650	COG1609	Transcriptional regulator
LGL93_RS00655	COG2610	gluconate transmembrane transporter activity
LGL93_RS00660	COG3265	gluconokinase activity
LGL93_RS00665	COG2095	MarC family integral membrane protein
LGL93_RS00670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL93_RS00675	COG3275	phosphorelay sensor kinase activity
LGL93_RS00680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL93_RS00685	COG1523	belongs to the glycosyl hydrolase 13 family
LGL93_RS00690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL93_RS00695	COG0297	glycogen (starch) synthase activity
LGL93_RS00700	COG0058	SHG alpha-glucan phosphorylase activity
LGL93_RS00705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL93_RS00710	COG1349	DNA-binding transcription factor activity
LGL93_RS00715	COG0705	Rhomboid family
LGL93_RS00725	COG2909	trisaccharide binding
LGL93_RS00730	COG0058	SHG alpha-glucan phosphorylase activity
LGL93_RS00735	COG1640	4-alpha-glucanotransferase
LGL93_RS00745	COG1040	competence protein
LGL93_RS00750	COG0596	Alpha beta hydrolase
LGL93_RS00770	COG1918	ferrous iron import across plasma membrane
LGL93_RS00775	COG2183	response to ionizing radiation
LGL93_RS00800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL93_RS00815	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL93_RS00825	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL93_RS00830	COG1011	Hydrolase
LGL93_RS00840	COG0494	nUDIX hydrolase
LGL93_RS00845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL93_RS00870	COG4796	Type ii and iii secretion system protein
LGL93_RS00875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL93_RS00895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL93_RS00905	COG0180	Tryptophanyl-tRNA synthetase
LGL93_RS00925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL93_RS00930	COG0402	S-adenosylhomocysteine deaminase activity
LGL93_RS00935	COG0738	Major facilitator superfamily
LGL93_RS00950	COG1609	Transcriptional regulator
LGL93_RS00955	COG1486	melibiose metabolic process
LGL93_RS00960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL93_RS00975	COG1289	transmembrane transporter activity
LGL93_RS00980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL93_RS00985	COG1765	OsmC-like protein
LGL93_RS01010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL93_RS01015	COG3954	Phosphoribulokinase
LGL93_RS01025	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL93_RS01035	COG0859	PFAM glycosyl transferase family 9
LGL93_RS01040	COG1216	Glycosyl transferase, family 2
LGL93_RS01045	COG0488	(ABC) transporter
LGL93_RS01050	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL93_RS01060	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL93_RS01065	COG1047	Peptidyl-prolyl cis-trans
LGL93_RS01075	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL93_RS01080	COG2964	Protein conserved in bacteria
LGL93_RS01090	COG2923	Belongs to the DsrF TusC family
LGL93_RS01095	COG2168	tRNA wobble position uridine thiolation
LGL93_RS01100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL93_RS01105	COG0049	tRNA binding
LGL93_RS01115	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL93_RS01130	COG0051	transcription antitermination factor activity, RNA binding
LGL93_RS01135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL93_RS01145	COG0089	rRNA binding
LGL93_RS01150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL93_RS01155	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL93_RS01160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL93_RS01170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL93_RS01175	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL93_RS01180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL93_RS01185	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL93_RS01195	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL93_RS01220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL93_RS01225	COG1841	ribosomal large subunit assembly
LGL93_RS01230	COG0200	Binds to the 23S rRNA
LGL93_RS01235	COG0201	protein transport
LGL93_RS01240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL93_RS01245	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL93_RS01255	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL93_RS01265	COG0203	ribosomal protein L17
LGL93_RS01270	COG0789	Transcriptional regulator
LGL93_RS01275	COG3036	rescue of stalled ribosome
LGL93_RS01280	COG1970	mechanosensitive ion channel activity
LGL93_RS01290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL93_RS01290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL93_RS01295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL93_RS01300	COG0242	peptide deformylase activity
LGL93_RS01305	COG0758	DNA mediated transformation
LGL93_RS01310	COG2922	Belongs to the Smg family
LGL93_RS01315	COG0551	DNA topoisomerase type I activity
LGL93_RS01320	COG0009	L-threonylcarbamoyladenylate synthase
LGL93_RS01330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL93_RS01360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL93_RS01365	COG3162	membrane
LGL93_RS01370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL93_RS01375	COG1301	dicarboxylic acid transport
LGL93_RS01380	COG2391	methyltransferase activity
LGL93_RS01385	COG0425	Belongs to the sulfur carrier protein TusA family
LGL93_RS01395	COG1086	Polysaccharide biosynthesis protein
LGL93_RS01400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL93_RS01405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL93_RS01410	COG2089	acid synthase
LGL93_RS01430	COG2755	lipolytic protein G-D-S-L family
LGL93_RS01430	COG1083	cytidylyl-transferase
LGL93_RS01435	COG1028	Short-chain dehydrogenase reductase Sdr
LGL93_RS01455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL93_RS01455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL93_RS01460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGL93_RS01480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL93_RS01500	COG1309	transcriptional regulator
LGL93_RS01505	COG4232	protein-disulfide reductase activity
LGL93_RS01545	COG1509	lysine 2,3-aminomutase activity
LGL93_RS01555	COG3397	chitin binding
LGL93_RS01575	COG3188	usher protein
LGL93_RS01595	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL93_RS01600	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL93_RS01605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL93_RS01610	COG1053	succinate dehydrogenase
LGL93_RS01615	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL93_RS01620	COG3264	Mechanosensitive ion channel
LGL93_RS01620	COG1511	domain protein
LGL93_RS01625	COG0688	phosphatidylethanolamine metabolic process
LGL93_RS01630	COG1162	GTPase activity
LGL93_RS01635	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL93_RS01655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL93_RS01660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL93_RS01660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL93_RS01665	COG0802	atpase or kinase
LGL93_RS01670	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL93_RS01680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL93_RS01690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL93_RS01695	COG0330	HflC and HflK could
LGL93_RS01700	COG0330	HflC and HflK could
LGL93_RS01705	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL93_RS01710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL93_RS01715	COG1959	2 iron, 2 sulfur cluster binding
LGL93_RS01720	COG0557	exoribonuclease II activity
LGL93_RS01725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL93_RS01745	COG3121	Chaperone
LGL93_RS01750	COG3188	usher protein
LGL93_RS01770	COG1073	alpha beta
LGL93_RS01780	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL93_RS01785	COG2965	DNA replication, synthesis of RNA primer
LGL93_RS01790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL93_RS01795	COG0359	binds to the 23S rRNA
LGL93_RS01800	COG3061	Opacity-associated protein A
LGL93_RS01805	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL93_RS01815	COG0737	Belongs to the 5'-nucleotidase family
LGL93_RS01825	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL93_RS01830	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL93_RS01840	COG1253	flavin adenine dinucleotide binding
LGL93_RS01845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL93_RS01850	COG0729	surface antigen
LGL93_RS01855	COG2911	Protein conserved in bacteria
LGL93_RS01860	COG2105	PFAM AIG2 family protein
LGL93_RS01865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL93_RS01875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL93_RS01890	COG3423	Transcriptional regulator
LGL93_RS01905	COG0142	geranyltranstransferase activity
LGL93_RS01920	COG0697	spore germination
LGL93_RS01925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL93_RS01930	COG0642	Histidine kinase
LGL93_RS01935	COG0745	RESPONSE REGULATOR receiver
LGL93_RS01940	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL93_RS01950	COG1534	Rna-binding protein
LGL93_RS01955	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL93_RS01965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL93_RS01970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL93_RS01975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL93_RS01995	COG0195	Participates in both transcription termination and antitermination
LGL93_RS02005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL93_RS02020	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL93_RS02030	COG0513	Belongs to the DEAD box helicase family
LGL93_RS02035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL93_RS02040	COG0814	amino acid
LGL93_RS02050	COG0826	peptidase U32
LGL93_RS02055	COG0826	peptidase U32
LGL93_RS02060	COG3154	lipid carrier protein
LGL93_RS02065	COG3153	acetyltransferase
LGL93_RS02070	COG2827	Endonuclease containing a URI domain
LGL93_RS02075	COG0531	amino acid
LGL93_RS02080	COG1982	Orn Lys Arg decarboxylase major
LGL93_RS02090	COG3787	Belongs to the UPF0306 family
LGL93_RS02095	COG0702	epimerase
LGL93_RS02100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL93_RS02105	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL93_RS02110	COG3454	Phosphonate metabolism
LGL93_RS02115	COG4778	phosphonate C-P lyase system protein PhnL
LGL93_RS02120	COG4107	phosphonate C-P lyase system protein PhnK
LGL93_RS02125	COG3627	carbon phosphorus lyase activity
LGL93_RS02130	COG3626	phosphonate metabolism
LGL93_RS02135	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL93_RS02140	COG3624	Phosphonate C-P lyase system protein PhnG
LGL93_RS02160	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL93_RS02175	COG2927	DNA polymerase III (CHI subunit)
LGL93_RS02180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL93_RS02185	COG0795	lipopolysaccharide-transporting ATPase activity
LGL93_RS02190	COG0795	lipopolysaccharide-transporting ATPase activity
LGL93_RS02245	COG5492	domain, Protein
LGL93_RS02265	COG3119	arylsulfatase activity
LGL93_RS02270	COG1349	DNA-binding transcription factor activity
LGL93_RS02280	COG2222	sugar isomerase
LGL93_RS02285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL93_RS02290	COG3715	PTS system
LGL93_RS02295	COG3716	PTS system mannose fructose sorbose family IID component
LGL93_RS02305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL93_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
LGL93_RS02325	COG0641	radical SAM
LGL93_RS02330	COG3119	arylsulfatase activity
LGL93_RS02355	COG0859	PFAM glycosyl transferase family 9
LGL93_RS02370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL93_RS02375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL93_RS02385	COG2376	Dihydroxyacetone kinase
LGL93_RS02390	COG1461	Dihydroxyacetone kinase
LGL93_RS02395	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL93_RS02395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL93_RS02395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL93_RS02435	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL93_RS02450	COG2823	Periplasmic or secreted lipoprotein
LGL93_RS02460	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL93_RS02465	COG0084	hydrolase, TatD family'
LGL93_RS02470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL93_RS02485	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL93_RS02495	COG3726	membrane protein affecting hemolysin expression
LGL93_RS02500	COG0560	Phosphoserine phosphatase
LGL93_RS02515	COG0488	(ABC) transporter
LGL93_RS02535	COG0741	lytic transglycosylase activity
LGL93_RS02540	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL93_RS02545	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL93_RS02550	COG0406	alpha-ribazole phosphatase activity
LGL93_RS02555	COG3708	Transcriptional regulator
LGL93_RS02555	COG2207	Transcriptional regulator
LGL93_RS02560	COG3045	CreA protein
LGL93_RS02565	COG0745	RESPONSE REGULATOR receiver
LGL93_RS02600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL93_RS02605	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL93_RS02610	COG0477	Major facilitator Superfamily
LGL93_RS02620	COG1584	GPR1 FUN34 yaaH family protein
LGL93_RS02625	COG0443	Heat shock 70 kDa protein
LGL93_RS02635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL93_RS02640	COG0583	DNA-binding transcription factor activity
LGL93_RS02650	COG0196	riboflavin kinase activity
LGL93_RS02660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL93_RS02665	COG1047	Peptidyl-prolyl cis-trans
LGL93_RS02670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL93_RS02685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL93_RS02695	COG2966	Psort location CytoplasmicMembrane, score
LGL93_RS02720	COG2967	ApaG domain
LGL93_RS02725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL93_RS02730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL93_RS02740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL93_RS02750	COG0564	pseudouridine synthase activity
LGL93_RS02755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL93_RS02760	COG0417	DNA replication proofreading
LGL93_RS02765	COG0586	Pfam SNARE associated Golgi protein
LGL93_RS02775	COG1178	ABC-type Fe3 transport system permease component
LGL93_RS02780	COG4143	(ABC) transporter
LGL93_RS02795	COG2814	Major facilitator Superfamily
LGL93_RS02805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL93_RS02810	COG0473	3-isopropylmalate dehydrogenase activity
LGL93_RS02825	COG1022	Amp-dependent synthetase and ligase
LGL93_RS02830	COG0028	Belongs to the TPP enzyme family
LGL93_RS02850	COG0675	Transposase, IS605 OrfB family
LGL93_RS02865	COG0275	rRNA processing
LGL93_RS02870	COG3116	cell division
LGL93_RS02875	COG0768	penicillin binding
LGL93_RS02880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL93_RS02885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL93_RS02900	COG0772	Belongs to the SEDS family
LGL93_RS02905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL93_RS02910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL93_RS02925	COG0849	cell division
LGL93_RS02930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL93_RS02955	COG0494	nUDIX hydrolase
LGL93_RS02975	COG0516	GMP reductase activity
LGL93_RS02980	COG1459	type II secretion system
LGL93_RS02985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL93_RS02990	COG4969	Belongs to the N-Me-Phe pilin family
LGL93_RS03005	COG3725	Membrane protein required for beta-lactamase induction
LGL93_RS03010	COG1113	amino acid transport
LGL93_RS03015	COG2186	Transcriptional regulator
LGL93_RS03020	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL93_RS03025	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL93_RS03030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL93_RS03040	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL93_RS03045	COG3112	Uncharacterised protein family (UPF0231)
LGL93_RS03060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL93_RS03070	COG2132	Multicopper oxidase
LGL93_RS03080	COG0288	reversible hydration of carbon dioxide
LGL93_RS03085	COG1131	(ABC) transporter
LGL93_RS03090	COG0842	Transport permease protein
LGL93_RS03095	COG0726	polysaccharide deacetylase
LGL93_RS03100	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL93_RS03105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL93_RS03110	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL93_RS03115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL93_RS03120	COG0617	tRNA 3'-terminal CCA addition
LGL93_RS03135	COG1489	DNA binding
LGL93_RS03140	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL93_RS03145	COG1643	Atp-dependent helicase
LGL93_RS03150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL93_RS03155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL93_RS03165	COG0316	Belongs to the HesB IscA family
LGL93_RS03170	COG2860	membrane
LGL93_RS03180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL93_RS03185	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL93_RS03190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL93_RS03200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL93_RS03205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL93_RS03210	COG3956	TIGRFAM MazG family protein
LGL93_RS03215	COG0504	CTP synthase activity
LGL93_RS03225	COG0602	queuosine metabolic process
LGL93_RS03230	COG0720	synthase
LGL93_RS03235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL93_RS03245	COG0175	sulfate reduction
LGL93_RS03260	COG2234	aminopeptidase activity
LGL93_RS03265	COG1648	precorrin-2 dehydrogenase activity
LGL93_RS03265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL93_RS03270	COG0175	sulfate reduction
LGL93_RS03275	COG2895	sulfate adenylyltransferase (ATP) activity
LGL93_RS03280	COG0529	Catalyzes the synthesis of activated sulfate
LGL93_RS03290	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL93_RS03300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL93_RS03305	COG0585	pseudouridine synthase activity
LGL93_RS03310	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL93_RS03320	COG4942	peptidase
LGL93_RS03320	COG1388	LysM domain
LGL93_RS03325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL93_RS03330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL93_RS03405	COG2205	protein histidine kinase activity
LGL93_RS03405	COG0784	Response regulator, receiver
LGL93_RS03425	COG0741	lytic transglycosylase activity
LGL93_RS03555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL93_RS03575	COG2963	transposase activity
LGL93_RS03595	COG3397	chitin binding
LGL93_RS03605	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL93_RS03650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL93_RS03660	COG3031	protein transport across the cell outer membrane
LGL93_RS03685	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL93_RS03685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL93_RS03700	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL93_RS03705	COG2137	regulation of response to DNA damage stimulus
LGL93_RS03710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL93_RS03715	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL93_RS03745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL93_RS03750	COG1238	metal cluster binding
LGL93_RS03755	COG2918	glutathione biosynthetic process
LGL93_RS03760	COG1854	S-ribosylhomocysteine lyase activity
LGL93_RS03765	COG4536	flavin adenine dinucleotide binding
LGL93_RS03770	COG4137	Cytochrome C assembly protein
LGL93_RS03775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL93_RS03785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL93_RS03790	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL93_RS03795	COG0335	large ribosomal subunit rRNA binding
LGL93_RS03800	COG3137	Salt-induced outer membrane protein
LGL93_RS03805	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL93_RS03810	COG3279	Response regulator of the LytR AlgR family
LGL93_RS03815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL93_RS03820	COG1605	Chorismate mutase
LGL93_RS03820	COG0287	Prephenate dehydrogenase
LGL93_RS03825	COG1605	Chorismate mutase
LGL93_RS03825	COG0077	Prephenate dehydratase
LGL93_RS03835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL93_RS03840	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL93_RS03845	COG0564	pseudouridine synthase activity
LGL93_RS03850	COG1496	oxidoreductase activity
LGL93_RS03855	COG0542	response to heat
LGL93_RS03890	COG3021	interspecies interaction between organisms
LGL93_RS03895	COG1388	LysM domain
LGL93_RS03895	COG0741	lytic transglycosylase activity
LGL93_RS03905	COG2226	methyltransferase
LGL93_RS03915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL93_RS03925	COG1960	acyl-CoA dehydrogenase activity
LGL93_RS03930	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL93_RS03935	COG0121	glutamine amidotransferase
LGL93_RS03940	COG3034	peptidoglycan biosynthetic process
LGL93_RS03950	COG1805	sodium ion transport
LGL93_RS03955	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL93_RS03960	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL93_RS03965	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL93_RS03975	COG1477	protein flavinylation
LGL93_RS03980	COG2991	Protein conserved in bacteria
LGL93_RS03990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL93_RS03995	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL93_RS04000	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL93_RS04005	COG1073	alpha beta
LGL93_RS04020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL93_RS04055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL93_RS04075	COG4126	flavin adenine dinucleotide binding
LGL93_RS04085	COG2974	May be involved in recombination
LGL93_RS04090	COG1940	carbohydrate kinase activity
LGL93_RS04095	COG0419	ATPase involved in DNA repair
LGL93_RS04100	COG0420	3'-5' exonuclease activity
LGL93_RS04105	COG0745	RESPONSE REGULATOR receiver
LGL93_RS04110	COG5002	protein histidine kinase activity
LGL93_RS04125	COG1113	amino acid transport
LGL93_RS04130	COG0366	Alpha amylase catalytic
LGL93_RS04135	COG0300	oxidoreductase activity
LGL93_RS04140	COG0450	alkyl hydroperoxide reductase
LGL93_RS04145	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL93_RS04160	COG1862	Preprotein translocase
LGL93_RS04165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL93_RS04170	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL93_RS04175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL93_RS04180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL93_RS04180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL93_RS04185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL93_RS04195	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL93_RS04200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL93_RS04205	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL93_RS04210	COG0142	geranyltranstransferase activity
LGL93_RS04245	COG0693	protein deglycase activity
LGL93_RS04250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL93_RS04255	COG1666	GTP binding
LGL93_RS04260	COG2814	Major facilitator Superfamily
LGL93_RS04270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL93_RS04275	COG1845	cytochrome c oxidase, subunit III
LGL93_RS04280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL93_RS04285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL93_RS04295	COG2223	nitrite transmembrane transporter activity
LGL93_RS04300	COG3056	Lipoprotein
LGL93_RS04305	COG0271	Belongs to the BolA IbaG family
LGL93_RS04315	COG0740	serine-type endopeptidase activity
LGL93_RS04320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL93_RS04325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL93_RS04330	COG0776	regulation of translation
LGL93_RS04335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL93_RS04340	COG1555	photosystem II stabilization
LGL93_RS04345	COG0824	Thioesterase
LGL93_RS04350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL93_RS04355	COG4533	DNA binding
LGL93_RS04370	COG1522	sequence-specific DNA binding
LGL93_RS04375	COG1132	(ABC) transporter
LGL93_RS04380	COG1132	(ABC) transporter
LGL93_RS04385	COG0347	Belongs to the P(II) protein family
LGL93_RS04390	COG0004	ammonium transporteR
LGL93_RS04395	COG1946	Acyl-CoA thioesterase
LGL93_RS04400	COG3695	enzyme binding
LGL93_RS04425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL93_RS04430	COG0254	rRNA binding
LGL93_RS04435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL93_RS04440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL93_RS04445	COG1309	transcriptional regulator
LGL93_RS04450	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL93_RS04455	COG1196	nuclear chromosome segregation
LGL93_RS04455	COG3264	Mechanosensitive ion channel
LGL93_RS04470	COG2832	Protein of unknown function (DUF454)
LGL93_RS04475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL93_RS04515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL93_RS04520	COG0326	Molecular chaperone. Has ATPase activity
LGL93_RS04535	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL93_RS04545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL93_RS04545	COG4651	solute:proton antiporter activity
LGL93_RS04550	COG0737	Belongs to the 5'-nucleotidase family
LGL93_RS04555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL93_RS04560	COG3735	TraB family
LGL93_RS04565	COG2217	Heavy metal translocating P-type atpase
LGL93_RS04570	COG0789	Transcriptional regulator
LGL93_RS04575	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL93_RS04580	COG0330	HflC and HflK could
LGL93_RS04585	COG3118	belongs to the thioredoxin family
LGL93_RS04590	COG0300	oxidoreductase activity
LGL93_RS04595	COG2755	lipolytic protein G-D-S-L family
LGL93_RS04600	COG4181	ATPase activity
LGL93_RS04605	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL93_RS04610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL93_RS04615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL93_RS04620	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL93_RS04625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL93_RS04650	COG3188	usher protein
LGL93_RS04655	COG3121	Chaperone
LGL93_RS04685	COG2501	S4 domain
LGL93_RS04690	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL93_RS04700	COG0582	viral genome integration into host DNA
LGL93_RS04720	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LGL93_RS04725	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LGL93_RS04740	COG0732	type I restriction modification DNA specificity domain
LGL93_RS04745	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LGL93_RS04775	COG3596	GTP binding
LGL93_RS04805	COG2003	Belongs to the UPF0758 family
LGL93_RS04835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL93_RS04840	COG1393	Belongs to the ArsC family
LGL93_RS04850	COG1022	Amp-dependent synthetase and ligase
LGL93_RS04875	COG3038	cytochrome b561
LGL93_RS04905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL93_RS04915	COG1215	transferase activity, transferring glycosyl groups
LGL93_RS04935	COG3250	beta-galactosidase activity
LGL93_RS04950	COG1309	transcriptional regulator
LGL93_RS04980	COG2197	response regulator
LGL93_RS04985	COG1278	Cold shock
LGL93_RS05005	COG3706	GGDEF domain
LGL93_RS05015	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL93_RS05025	COG2921	Belongs to the UPF0250 family
LGL93_RS05030	COG1686	Belongs to the peptidase S11 family
LGL93_RS05035	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL93_RS05040	COG0772	Belongs to the SEDS family
LGL93_RS05045	COG0768	penicillin binding
LGL93_RS05050	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL93_RS05055	COG0799	negative regulation of ribosome biogenesis
LGL93_RS05060	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL93_RS05065	COG1466	dna polymerase III delta subunit
LGL93_RS05070	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL93_RS05080	COG2888	peptidyl-tyrosine sulfation
LGL93_RS05085	COG1126	abc transporter atp-binding protein
LGL93_RS05090	COG0765	amino acid transport
LGL93_RS05095	COG0765	amino acid transport
LGL93_RS05105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL93_RS05110	COG4535	Mg2 and Co2 transporter CorC
LGL93_RS05115	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL93_RS05120	COG1702	phosphate starvation-inducible protein PhoH
LGL93_RS05125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL93_RS05130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL93_RS05165	COG0367	asparagine synthase
LGL93_RS05170	COG0647	UMP catabolic process
LGL93_RS05175	COG1846	Transcriptional regulator
LGL93_RS05175	COG1940	carbohydrate kinase activity
LGL93_RS05180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL93_RS05190	COG2190	(PTS) system
LGL93_RS05190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL93_RS05190	COG1263	PTS System
LGL93_RS05215	COG0735	belongs to the Fur family
LGL93_RS05225	COG0840	transmembrane signaling receptor activity
LGL93_RS05235	COG0596	Alpha beta hydrolase
LGL93_RS05240	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL93_RS05245	COG0033	Phosphoglucomutase
LGL93_RS05255	COG0745	RESPONSE REGULATOR receiver
LGL93_RS05260	COG2205	protein histidine kinase activity
LGL93_RS05265	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL93_RS05270	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL93_RS05290	COG3272	Protein of unknown function (DUF1722)
LGL93_RS05295	COG0415	Belongs to the DNA photolyase family
LGL93_RS05300	COG5212	phosphodiesterase
LGL93_RS05305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL93_RS05310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL93_RS05320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL93_RS05355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL93_RS05360	COG1053	succinate dehydrogenase
LGL93_RS05365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL93_RS05370	COG0567	Dehydrogenase, E1 component
LGL93_RS05375	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL93_RS05380	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL93_RS05385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL93_RS05390	COG0737	Belongs to the 5'-nucleotidase family
LGL93_RS05395	COG1271	oxidase subunit
LGL93_RS05400	COG1294	oxidase, subunit
LGL93_RS05405	COG4890	Cyd operon protein YbgT
LGL93_RS05410	COG3790	cyd operon protein YbgE
LGL93_RS05415	COG0824	Thioesterase
LGL93_RS05420	COG0811	peptide transport
LGL93_RS05425	COG0848	biopolymer transport protein
LGL93_RS05430	COG3064	Membrane
LGL93_RS05430	COG3064	Membrane
LGL93_RS05435	COG0823	Involved in the tonB-independent uptake of proteins
LGL93_RS05440	COG2885	chlorophyll binding
LGL93_RS05445	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL93_RS05485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL93_RS05495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL93_RS05495	COG2205	protein histidine kinase activity
LGL93_RS05505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL93_RS05510	COG0588	phosphoglycerate mutase activity
LGL93_RS05520	COG2017	converts alpha-aldose to the beta-anomer
LGL93_RS05530	COG1085	galactose-1-phosphate uridylyltransferase
LGL93_RS05535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL93_RS05550	COG3585	molybdate ion transport
LGL93_RS05550	COG2005	Transcriptional regulator
LGL93_RS05560	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL93_RS05565	COG4149	molybdate abc transporter
LGL93_RS05575	COG0561	phosphatase activity
LGL93_RS05580	COG2706	6-phosphogluconolactonase activity
LGL93_RS05595	COG0156	8-amino-7-oxononanoate synthase activity
LGL93_RS05600	COG2226	methyltransferase
LGL93_RS05615	COG0556	nucleotide-excision repair
LGL93_RS05620	COG4628	conserved protein (DUF2132)
LGL93_RS05635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL93_RS05640	COG1120	ATPase activity
LGL93_RS05645	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL93_RS05650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL93_RS05660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL93_RS05665	COG0314	molybdopterin synthase activity
LGL93_RS05670	COG0670	Belongs to the BI1 family
LGL93_RS05675	COG0842	Transport permease protein
LGL93_RS05680	COG0842	Transport permease protein
LGL93_RS05685	COG1131	(ABC) transporter
LGL93_RS05690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL93_RS05695	COG1309	transcriptional regulator
LGL93_RS05700	COG0513	Belongs to the DEAD box helicase family
LGL93_RS05705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL93_RS05715	COG1686	Belongs to the peptidase S11 family
LGL93_RS05720	COG0277	FAD linked oxidase domain protein
LGL93_RS05740	COG2261	transglycosylase associated protein
LGL93_RS05750	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL93_RS05760	COG3639	organic phosphonate transmembrane transporter activity
LGL93_RS05765	COG4807	Protein conserved in bacteria
LGL93_RS05770	COG2897	thiosulfate sulfurtransferase activity
LGL93_RS05775	COG1732	Glycine betaine
LGL93_RS05780	COG1174	glycine betaine transport
LGL93_RS05785	COG1125	glycine betaine transport
LGL93_RS05790	COG1174	glycine betaine transport
LGL93_RS05795	COG0531	amino acid
LGL93_RS05800	COG1982	Orn Lys Arg decarboxylase major
LGL93_RS05810	COG0697	spore germination
LGL93_RS05825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL93_RS05830	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL93_RS05835	COG1126	abc transporter atp-binding protein
LGL93_RS05840	COG0765	amino acid transport
LGL93_RS05845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL93_RS05860	COG5006	permease, DMT superfamily
LGL93_RS05865	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL93_RS05870	COG2239	Acts as a magnesium transporter
LGL93_RS05875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL93_RS05880	COG0488	(ABC) transporter
LGL93_RS05885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL93_RS05890	COG0303	'Molybdopterin
LGL93_RS05910	COG0583	DNA-binding transcription factor activity
LGL93_RS05915	COG0477	Major facilitator Superfamily
LGL93_RS05920	COG0302	gtp cyclohydrolase
LGL93_RS05925	COG2311	Membrane
LGL93_RS05950	COG2949	membrane
LGL93_RS05955	COG0281	malic enzyme
LGL93_RS05965	COG0583	DNA-binding transcription factor activity
LGL93_RS05975	COG1346	cytolysis
LGL93_RS05980	COG1380	Effector of murein hydrolase LrgA
LGL93_RS05990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL93_RS05990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL93_RS05995	COG0489	protein tyrosine kinase activity
LGL93_RS06000	COG0572	uridine kinase
LGL93_RS06005	COG0717	Belongs to the dCTP deaminase family
LGL93_RS06010	COG2982	Protein involved in outer membrane biogenesis
LGL93_RS06015	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL93_RS06020	COG1253	flavin adenine dinucleotide binding
LGL93_RS06025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL93_RS06030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL93_RS06035	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL93_RS06045	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL93_RS06045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL93_RS06055	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL93_RS06065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL93_RS06065	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL93_RS06070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL93_RS06075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL93_RS06090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL93_RS06095	COG0625	glutathione transferase activity
LGL93_RS06110	COG0626	cystathionine gamma-synthase activity
LGL93_RS06120	COG1686	Belongs to the peptidase S11 family
LGL93_RS06125	COG1760	l-serine dehydratase
LGL93_RS06130	COG0814	amino acid
LGL93_RS06135	COG1349	DNA-binding transcription factor activity
LGL93_RS06145	COG0671	phosphoesterase, PA-phosphatase related
LGL93_RS06200	COG2985	domain, Protein
LGL93_RS06200	COG0569	domain protein
LGL93_RS06220	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL93_RS06225	COG3842	ATPase activity
LGL93_RS06230	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL93_RS06250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL93_RS06255	COG4160	amino acid transport
LGL93_RS06260	COG4215	(ABC) transporter
LGL93_RS06265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL93_RS06270	COG1126	abc transporter atp-binding protein
LGL93_RS06280	COG0393	Putative heavy-metal-binding
LGL93_RS06285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL93_RS06290	COG0702	epimerase
LGL93_RS06295	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL93_RS06300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL93_RS06305	COG1151	hydroxylamine reductase activity
LGL93_RS06310	COG2431	L-lysine efflux transmembrane transporter activity
LGL93_RS06315	COG3593	DNA synthesis involved in DNA repair
LGL93_RS06320	COG2990	Protein conserved in bacteria
LGL93_RS06325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL93_RS06335	COG1278	Cold shock
LGL93_RS06340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL93_RS06345	COG0542	response to heat
LGL93_RS06350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL93_RS06360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL93_RS06370	COG0492	ferredoxin-NADP+ reductase activity
LGL93_RS06375	COG1522	sequence-specific DNA binding
LGL93_RS06380	COG1674	ftsk spoiiie
LGL93_RS06380	COG3107	peptidoglycan biosynthetic process
LGL93_RS06385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL93_RS06390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL93_RS06395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL93_RS06400	COG2814	Major facilitator Superfamily
LGL93_RS06405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL93_RS06410	COG1882	Formate acetyltransferase
LGL93_RS06415	COG2116	formate transmembrane transporter activity
LGL93_RS06420	COG1944	ATP diphosphatase activity
LGL93_RS06425	COG0252	asparaginase activity
LGL93_RS06435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL93_RS06445	COG0539	negative regulation of cytoplasmic translation
LGL93_RS06455	COG0658	competence protein
LGL93_RS06455	COG2333	competence protein COMEC
LGL93_RS06465	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL93_RS06470	COG5383	Protein conserved in bacteria
LGL93_RS06480	COG1278	Cold shock
LGL93_RS06485	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL93_RS06490	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL93_RS06495	COG3173	Aminoglycoside phosphotransferase
LGL93_RS06500	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL93_RS06505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL93_RS06510	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL93_RS06520	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL93_RS06525	COG2989	Protein conserved in bacteria
LGL93_RS06530	COG3108	Peptidase M15
LGL93_RS06535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL93_RS06540	COG1448	Aminotransferase
LGL93_RS06555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL93_RS06560	COG0308	aminopeptidase N
LGL93_RS06565	COG0167	dihydroorotate dehydrogenase activity
LGL93_RS06580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL93_RS06580	COG0116	Belongs to the methyltransferase superfamily
LGL93_RS06585	COG0488	(ABC) transporter
LGL93_RS06590	COG2995	paraquat-inducible protein a
LGL93_RS06595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL93_RS06595	COG3008	intermembrane lipid transfer
LGL93_RS06600	COG3009	Protein conserved in bacteria
LGL93_RS06605	COG3130	regulation of translation
LGL93_RS06610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL93_RS06615	COG1067	ATP-dependent peptidase activity
LGL93_RS06620	COG3120	sequence-specific DNA binding
LGL93_RS06630	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL93_RS06635	COG3070	regulator of competence-specific genes
LGL93_RS06640	COG1289	transmembrane transporter activity
LGL93_RS06645	COG3304	Inner membrane component domain
LGL93_RS06650	COG0210	DNA helicase
LGL93_RS06655	COG1803	Methylglyoxal synthase
LGL93_RS06665	COG1832	CoA-binding protein
LGL93_RS06670	COG3785	DNA binding
LGL93_RS06675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL93_RS06680	COG1254	Belongs to the acylphosphatase family
LGL93_RS06685	COG2920	part of a sulfur-relay system
LGL93_RS06695	COG0288	reversible hydration of carbon dioxide
LGL93_RS06715	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL93_RS06720	COG2943	transferase activity, transferring hexosyl groups
LGL93_RS06740	COG1560	Kdo2-lipid A biosynthetic process
LGL93_RS06750	COG0628	permease
LGL93_RS06775	COG0418	dihydroorotase activity
LGL93_RS06780	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGL93_RS06790	COG1530	ribonuclease E activity
LGL93_RS06795	COG0564	pseudouridine synthase activity
LGL93_RS06800	COG0424	maF-like protein
LGL93_RS06805	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL93_RS06810	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL93_RS06820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL93_RS06825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL93_RS06835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL93_RS06840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL93_RS06845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL93_RS06850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL93_RS06855	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL93_RS06860	COG0470	DNA polymerase III
LGL93_RS06865	COG0084	hydrolase, TatD family'
LGL93_RS06870	COG1263	PTS System
LGL93_RS06870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL93_RS06875	COG0537	adenosine 5'-monophosphoramidase activity
LGL93_RS06880	COG5633	Lipoprotein
LGL93_RS06885	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL93_RS06900	COG3150	esterase
LGL93_RS06905	COG1252	NADH dehydrogenase
LGL93_RS06910	COG3134	Outer membrane lipoprotein
LGL93_RS06915	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL93_RS06920	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL93_RS06930	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL93_RS06950	COG2850	peptidyl-arginine hydroxylation
LGL93_RS06955	COG2205	protein histidine kinase activity
LGL93_RS06960	COG0745	RESPONSE REGULATOR receiver
LGL93_RS06970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL93_RS06975	COG2915	High frequency lysogenization protein hflD homolog
LGL93_RS06980	COG0482	sulfurtransferase activity
LGL93_RS06990	COG1187	pseudouridine synthase activity
LGL93_RS06995	COG0538	isocitrate dehydrogenase activity
LGL93_RS07000	COG2771	luxR family
LGL93_RS07005	COG3916	Acyl-homoserine-lactone synthase
LGL93_RS07010	COG2723	6-phospho-beta-galactosidase activity
LGL93_RS07020	COG0339	signal peptide processing
LGL93_RS07025	COG0840	transmembrane signaling receptor activity
LGL93_RS07030	COG3493	citrate carrier protein
LGL93_RS07035	COG4565	transcriptional regulatory protein
LGL93_RS07040	COG3290	protein histidine kinase activity
LGL93_RS07045	COG0471	metal ion transport
LGL93_RS07085	COG4977	sequence-specific DNA binding
LGL93_RS07090	COG1702	phosphate starvation-inducible protein PhoH
LGL93_RS07095	COG0387	Pfam Sodium calcium exchanger
LGL93_RS07100	COG2375	cellular response to nickel ion
LGL93_RS07105	COG3850	Histidine kinase
LGL93_RS07115	COG1294	oxidase, subunit
LGL93_RS07120	COG1271	oxidase subunit
LGL93_RS07125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL93_RS07130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL93_RS07135	COG3138	arginine N-succinyltransferase
LGL93_RS07145	COG3724	N-succinylarginine dihydrolase activity
LGL93_RS07165	COG1228	amidohydrolase
LGL93_RS07175	COG0402	S-adenosylhomocysteine deaminase activity
LGL93_RS07195	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL93_RS07200	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL93_RS07205	COG3383	formate dehydrogenase (NAD+) activity
LGL93_RS07210	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL93_RS07215	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL93_RS07225	COG3260	NADH ubiquinone oxidoreductase 20
LGL93_RS07230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL93_RS07235	COG3261	NADH dehydrogenase
LGL93_RS07235	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL93_RS07240	COG0650	Formate hydrogenlyase subunit 4
LGL93_RS07245	COG0651	ATP synthesis coupled electron transport
LGL93_RS07250	COG0651	ATP synthesis coupled electron transport
LGL93_RS07255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL93_RS07265	COG0375	protein maturation
LGL93_RS07270	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL93_RS07275	COG0298	carbon dioxide binding
LGL93_RS07280	COG0409	Hydrogenase expression formation protein
LGL93_RS07285	COG0309	Hydrogenase expression formation protein (HypE)
LGL93_RS07325	COG3708	Transcriptional regulator
LGL93_RS07325	COG2207	Transcriptional regulator
LGL93_RS07330	COG0012	GTP binding
LGL93_RS07340	COG0193	aminoacyl-tRNA hydrolase activity
LGL93_RS07350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL93_RS07360	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL93_RS07365	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL93_RS07370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL93_RS07375	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL93_RS07390	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL93_RS07395	COG0659	secondary active sulfate transmembrane transporter activity
LGL93_RS07400	COG3706	GGDEF domain
LGL93_RS07425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL93_RS07435	COG3381	protein complex oligomerization
LGL93_RS07455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL93_RS07470	COG0728	peptidoglycan biosynthetic process
LGL93_RS07500	COG3102	Protein conserved in bacteria
LGL93_RS07505	COG3142	Participates in the control of copper homeostasis
LGL93_RS07520	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL93_RS07525	COG1801	Protein of unknown function DUF72
LGL93_RS07535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL93_RS07540	COG0494	nUDIX hydrolase
LGL93_RS07550	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL93_RS07560	COG2255	four-way junction helicase activity
LGL93_RS07565	COG3104	oligopeptide transport
LGL93_RS07570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL93_RS07575	COG1121	(ABC) transporter
LGL93_RS07580	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL93_RS07585	COG0739	heme binding
LGL93_RS07590	COG1560	Kdo2-lipid A biosynthetic process
LGL93_RS07595	COG0469	pyruvate kinase activity
LGL93_RS07600	COG1737	Transcriptional regulator
LGL93_RS07605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL93_RS07610	COG0800	Aldolase
LGL93_RS07620	COG2076	Multidrug Resistance protein
LGL93_RS07625	COG0251	oxidation-reduction process
LGL93_RS07630	COG1199	ATP-dependent helicase activity
LGL93_RS07635	COG1214	PFAM Peptidase M22, glycoprotease
LGL93_RS07640	COG3065	identical protein binding
LGL93_RS07645	COG0318	PFAM AMP-dependent synthetase and ligase
LGL93_RS07650	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL93_RS07655	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL93_RS07660	COG2894	cell division
LGL93_RS07665	COG0850	regulation of cytokinetic process
LGL93_RS07670	COG3100	YcgL domain-containing protein
LGL93_RS07675	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL93_RS07680	COG2983	Belongs to the UPF0260 family
LGL93_RS07700	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL93_RS07710	COG2719	SpoVR family
LGL93_RS07715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL93_RS07720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL93_RS07725	COG2814	Major facilitator Superfamily
LGL93_RS07735	COG2199	diguanylate cyclase activity
LGL93_RS07735	COG2200	EAL domain
LGL93_RS07735	COG2202	Pas domain
LGL93_RS07755	COG2718	Belongs to the UPF0229 family
LGL93_RS07760	COG2766	serine protein kinase
LGL93_RS07770	COG3713	MltA-interacting MipA family protein
LGL93_RS07775	COG2194	sulfuric ester hydrolase activity
LGL93_RS07790	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL93_RS07795	COG3139	Protein of unknown function (DUF1315)
LGL93_RS07800	COG1335	isochorismatase
LGL93_RS07805	COG0252	asparaginase activity
LGL93_RS07810	COG0616	signal peptide processing
LGL93_RS07815	COG0778	Nitroreductase
LGL93_RS07825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL93_RS07835	COG0494	nUDIX hydrolase
LGL93_RS07840	COG0708	Exodeoxyribonuclease III
LGL93_RS07870	COG0788	formyltetrahydrofolate deformylase activity
LGL93_RS07875	COG3012	SEC-C Motif Domain Protein
LGL93_RS07885	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL93_RS07890	COG0745	RESPONSE REGULATOR receiver
LGL93_RS07915	COG1454	alcohol dehydrogenase
LGL93_RS07915	COG1012	belongs to the aldehyde dehydrogenase family
LGL93_RS07925	COG2095	MarC family integral membrane protein
LGL93_RS07930	COG4166	transmembrane transport
LGL93_RS07945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL93_RS07960	COG3099	Belongs to the UPF0263 family
LGL93_RS07965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL93_RS07985	COG2350	Protein conserved in bacteria
LGL93_RS08000	COG3710	Transcriptional regulator
LGL93_RS08035	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL93_RS08060	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL93_RS08065	COG3047	cAMP biosynthetic process
LGL93_RS08080	COG0133	tryptophan synthase activity
LGL93_RS08085	COG0134	indole-3-glycerol-phosphate synthase activity
LGL93_RS08085	COG0135	phosphoribosylanthranilate isomerase activity
LGL93_RS08095	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL93_RS08105	COG0613	PHP domain protein
LGL93_RS08110	COG0009	L-threonylcarbamoyladenylate synthase
LGL93_RS08115	COG1187	pseudouridine synthase activity
LGL93_RS08130	COG0616	signal peptide processing
LGL93_RS08145	COG0583	DNA-binding transcription factor activity
LGL93_RS08160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL93_RS08170	COG0671	phosphoesterase, PA-phosphatase related
LGL93_RS08175	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL93_RS08180	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL93_RS08200	COG0023	Translation Initiation Factor
LGL93_RS08210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL93_RS08215	COG5002	protein histidine kinase activity
LGL93_RS08215	COG3447	MASE1 domain protein
LGL93_RS08215	COG5001	Diguanylate cyclase
LGL93_RS08220	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL93_RS08225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL93_RS08235	COG4659	FMN binding
LGL93_RS08245	COG3708	Transcriptional regulator
LGL93_RS08245	COG2207	Transcriptional regulator
LGL93_RS08250	COG4656	Part of a membrane complex involved in electron transport
LGL93_RS08265	COG4657	Part of a membrane complex involved in electron transport
LGL93_RS08275	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL93_RS08285	COG0673	inositol 2-dehydrogenase activity
LGL93_RS08290	COG0385	Bile acid
LGL93_RS08295	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL93_RS08300	COG5339	Protein conserved in bacteria
LGL93_RS08305	COG1482	cell wall glycoprotein biosynthetic process
LGL93_RS08310	COG0114	fumarate hydratase activity
LGL93_RS08355	COG1742	UPF0060 membrane protein
LGL93_RS08360	COG4221	oxidoreductase activity
LGL93_RS08365	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL93_RS08385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL93_RS08415	COG1011	Hydrolase
LGL93_RS08425	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL93_RS08430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL93_RS08435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL93_RS08440	COG0589	response to stress
LGL93_RS08470	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL93_RS08475	COG3623	hexulose-6-phosphate isomerase
LGL93_RS08480	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL93_RS08485	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL93_RS08495	COG0531	amino acid
LGL93_RS08505	COG0745	RESPONSE REGULATOR receiver
LGL93_RS08510	COG2205	protein histidine kinase activity
LGL93_RS08525	COG2207	Transcriptional regulator
LGL93_RS08530	COG1881	PFAM PEBP family protein
LGL93_RS08540	COG3591	Belongs to the peptidase S1B family
LGL93_RS08545	COG1643	Atp-dependent helicase
LGL93_RS08550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL93_RS08555	COG3784	Protein of unknown function (DUF1318)
LGL93_RS08570	COG2911	Protein conserved in bacteria
LGL93_RS08575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL93_RS08580	COG3187	Heat shock protein
LGL93_RS08585	COG3042	response to heat
LGL93_RS08590	COG1285	pathogenesis
LGL93_RS08600	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL93_RS08600	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL93_RS08600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL93_RS08600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL93_RS08615	COG4166	transmembrane transport
LGL93_RS08620	COG2866	Carboxypeptidase
LGL93_RS08625	COG4948	Mandelate Racemase Muconate Lactonizing
LGL93_RS08630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL93_RS08640	COG5642	Protein of unknown function (DUF2384)
LGL93_RS08645	COG5654	RES domain protein
LGL93_RS08650	COG3768	UPF0283 membrane protein
LGL93_RS08655	COG3106	COG3106 Predicted ATPase
LGL93_RS08665	COG1983	PspC domain protein
LGL93_RS08675	COG1842	Phage shock protein A
LGL93_RS08695	COG4166	transmembrane transport
LGL93_RS08705	COG4171	peptide transport system, permease
LGL93_RS08710	COG4172	Belongs to the ABC transporter superfamily
LGL93_RS08715	COG4172	Belongs to the ABC transporter superfamily
LGL93_RS08725	COG3104	oligopeptide transport
LGL93_RS08735	COG0484	heat shock protein binding
LGL93_RS08780	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL93_RS08785	COG3133	Outer membrane lipoprotein
LGL93_RS08790	COG1846	Transcriptional regulator
LGL93_RS08800	COG4989	oxidoreductase activity
LGL93_RS08805	COG3313	Fe-S protein
LGL93_RS08810	COG2194	sulfuric ester hydrolase activity
LGL93_RS08815	COG1309	transcriptional regulator
LGL93_RS08820	COG1902	pentaerythritol trinitrate reductase activity
LGL93_RS08835	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL93_RS08840	COG0791	NLP P60 protein
LGL93_RS08845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL93_RS08855	COG1609	Transcriptional regulator
LGL93_RS08860	COG0583	DNA-binding transcription factor activity
LGL93_RS08865	COG2814	Major facilitator Superfamily
LGL93_RS08870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL93_RS08875	COG0307	riboflavin synthase, alpha
LGL93_RS08910	COG1376	ErfK ybiS ycfS ynhG family protein
LGL93_RS08910	COG1388	LysM domain
LGL93_RS08915	COG2166	iron-sulfur cluster assembly
LGL93_RS08925	COG0719	Fe-S assembly protein
LGL93_RS08930	COG0396	ATPase activity
LGL93_RS08935	COG0719	Fe-S assembly protein
LGL93_RS08940	COG0316	Belongs to the HesB IscA family
LGL93_RS08945	COG2050	protein possibly involved in aromatic compounds catabolism
LGL93_RS08950	COG0247	lactate metabolic process
LGL93_RS08950	COG0277	FAD linked oxidase domain protein
LGL93_RS08955	COG0628	permease
LGL93_RS08965	COG0574	Belongs to the PEP-utilizing enzyme family
LGL93_RS08965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL93_RS08970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL93_RS08975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL93_RS08985	COG4771	TonB-dependent receptor
LGL93_RS08990	COG3720	iron ion transport
LGL93_RS08995	COG4558	Periplasmic binding protein
LGL93_RS09000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL93_RS09005	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL93_RS09015	COG0095	Lipoate-protein ligase
LGL93_RS09020	COG0791	NLP P60 protein
LGL93_RS09025	COG2076	Multidrug Resistance protein
LGL93_RS09030	COG2076	Multidrug Resistance protein
LGL93_RS09035	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL93_RS09055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL93_RS09065	COG4139	cobalamin transport
LGL93_RS09110	COG0776	regulation of translation
LGL93_RS09180	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL93_RS09185	COG1121	(ABC) transporter
LGL93_RS09190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL93_RS09195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL93_RS09200	COG3001	Fructosamine kinase
LGL93_RS09210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL93_RS09215	COG1988	membrane-bound metal-dependent
LGL93_RS09220	COG1823	symporter activity
LGL93_RS09225	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL93_RS09235	COG2814	Major facilitator Superfamily
LGL93_RS09245	COG0501	Belongs to the peptidase M48B family
LGL93_RS09250	COG0793	Belongs to the peptidase S41A family
LGL93_RS09260	COG1956	GAF domain-containing protein
LGL93_RS09265	COG2995	paraquat-inducible protein a
LGL93_RS09270	COG3008	intermembrane lipid transfer
LGL93_RS09365	COG1276	copper resistance
LGL93_RS09370	COG2372	response to copper ion
LGL93_RS09375	COG1528	Iron-storage protein
LGL93_RS09390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL93_RS09395	COG1770	oligopeptidase
LGL93_RS09405	COG3097	Belongs to the UPF0267 family
LGL93_RS09410	COG3141	response to X-ray
LGL93_RS09415	COG0513	Belongs to the DEAD box helicase family
LGL93_RS09435	COG0494	nUDIX hydrolase
LGL93_RS09440	COG1760	l-serine dehydratase
LGL93_RS09445	COG1253	flavin adenine dinucleotide binding
LGL93_RS09450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL93_RS09450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL93_RS09455	COG3715	PTS system
LGL93_RS09460	COG3716	PTS system mannose fructose sorbose family IID component
LGL93_RS09465	COG4811	Protein of unknown function (DUF986)
LGL93_RS09470	COG1971	Probably functions as a manganese efflux pump
LGL93_RS09490	COG1960	acyl-CoA dehydrogenase activity
LGL93_RS09500	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL93_RS09530	COG2226	methyltransferase
LGL93_RS09540	COG1496	oxidoreductase activity
LGL93_RS09560	COG1113	amino acid transport
LGL93_RS09595	COG2207	Transcriptional regulator
LGL93_RS09615	COG1132	(ABC) transporter
LGL93_RS09625	COG3706	GGDEF domain
LGL93_RS09625	COG5001	Diguanylate cyclase
LGL93_RS09625	COG2203	Gaf domain
LGL93_RS09625	COG4251	negative regulation of phosphorylation
LGL93_RS09645	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL93_RS09665	COG1278	Cold shock
LGL93_RS09670	COG1278	Cold shock
LGL93_RS09685	COG2169	Transcriptional regulator
LGL93_RS09685	COG1917	Cupin 2, conserved barrel domain protein
LGL93_RS09690	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL93_RS09695	COG2723	6-phospho-beta-galactosidase activity
LGL93_RS09700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL93_RS09705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL93_RS09710	COG1187	pseudouridine synthase activity
LGL93_RS09725	COG3122	Protein conserved in bacteria
LGL93_RS09730	COG1757	Na H antiporter
LGL93_RS09745	COG2235	arginine
LGL93_RS09760	COG0076	glutamate decarboxylase activity
LGL93_RS09765	COG0531	amino acid
LGL93_RS09800	COG2153	protein acetylation
LGL93_RS09805	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL93_RS09835	COG0840	transmembrane signaling receptor activity
LGL93_RS09970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL93_RS09975	COG0322	excinuclease ABC activity
LGL93_RS09980	COG2197	response regulator
LGL93_RS10005	COG1113	amino acid transport
LGL93_RS10015	COG0531	amino acid
LGL93_RS10020	COG3710	Transcriptional regulator
LGL93_RS10025	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL93_RS10030	COG0506	proline dehydrogenase activity
LGL93_RS10030	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL93_RS10030	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL93_RS10035	COG1126	abc transporter atp-binding protein
LGL93_RS10040	COG0765	amino acid transport
LGL93_RS10045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL93_RS10050	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL93_RS10060	COG1191	sigma factor activity
LGL93_RS10095	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL93_RS10100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL93_RS10115	COG1677	Flagellar hook-basal body complex protein FliE
LGL93_RS10125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL93_RS10130	COG1317	bacterial-type flagellum organization
LGL93_RS10135	COG1157	protein secretion by the type III secretion system
LGL93_RS10150	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL93_RS10230	COG1558	bacterial-type flagellum-dependent cell motility
LGL93_RS10235	COG1815	bacterial-type flagellum-dependent cell motility
LGL93_RS10245	COG2747	anti-sigma28 factor FlgM
LGL93_RS10250	COG3418	PFAM FlgN family protein
LGL93_RS10260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL93_RS10265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL93_RS10270	COG1404	Belongs to the peptidase S8 family
LGL93_RS10270	COG4935	Belongs to the peptidase S8 family
LGL93_RS10275	COG2197	response regulator
LGL93_RS10290	COG3188	usher protein
LGL93_RS10300	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL93_RS10305	COG0745	RESPONSE REGULATOR receiver
LGL93_RS10315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL93_RS10320	COG0840	transmembrane signaling receptor activity
LGL93_RS10325	COG0840	transmembrane signaling receptor activity
LGL93_RS10335	COG0835	chemotaxis
LGL93_RS10340	COG2198	Histidine kinase
LGL93_RS10340	COG0643	Histidine kinase
LGL93_RS10345	COG1360	Flagellar Motor Protein
LGL93_RS10365	COG0589	response to stress
LGL93_RS10370	COG1285	pathogenesis
LGL93_RS10375	COG0840	transmembrane signaling receptor activity
LGL93_RS10395	COG1609	Transcriptional regulator
LGL93_RS10405	COG0604	alcohol dehydrogenase
LGL93_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
LGL93_RS10405	COG3321	synthase
LGL93_RS10450	COG1289	transmembrane transporter activity
LGL93_RS10460	COG2925	Exonuclease
LGL93_RS10465	COG0531	amino acid
LGL93_RS10470	COG4771	TonB-dependent receptor
LGL93_RS10480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL93_RS10490	COG0833	amino acid
LGL93_RS10495	COG0583	DNA-binding transcription factor activity
LGL93_RS10505	COG2855	membrane
LGL93_RS10510	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL93_RS10515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL93_RS10515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL93_RS10515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL93_RS10520	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL93_RS10535	COG3005	denitrification pathway
LGL93_RS10540	COG0243	molybdopterin cofactor binding
LGL93_RS10560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL93_RS10570	COG0246	Mannitol dehydrogenase
LGL93_RS10580	COG0523	cobalamin synthesis protein
LGL93_RS10585	COG0671	phosphoesterase, PA-phosphatase related
LGL93_RS10590	COG0791	NLP P60 protein
LGL93_RS10595	COG2200	EAL domain
LGL93_RS10600	COG4166	transmembrane transport
LGL93_RS10605	COG4174	ABC transporter (Permease)
LGL93_RS10610	COG4239	(ABC) transporter, permease
LGL93_RS10615	COG4172	Belongs to the ABC transporter superfamily
LGL93_RS10625	COG2814	Major facilitator Superfamily
LGL93_RS10630	COG1187	pseudouridine synthase activity
LGL93_RS10635	COG1061	Type III restriction enzyme res subunit
LGL93_RS10650	COG3082	Protein of unknown function (DUF1414)
LGL93_RS10655	COG3083	sulfuric ester hydrolase activity
LGL93_RS10665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGL93_RS10690	COG3299	homolog of phage Mu protein gp47
LGL93_RS10735	COG4386	tail sheath protein
LGL93_RS10775	COG0616	signal peptide processing
LGL93_RS10810	COG3646	Phage regulatory protein
LGL93_RS10820	COG0675	Transposase, IS605 OrfB family
LGL93_RS10855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL93_RS10860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL93_RS10880	COG2223	nitrite transmembrane transporter activity
LGL93_RS10885	COG2198	Histidine kinase
LGL93_RS10885	COG0642	Histidine kinase
LGL93_RS10895	COG2205	protein histidine kinase activity
LGL93_RS10895	COG0784	Response regulator, receiver
LGL93_RS10905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL93_RS10910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL93_RS10920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL93_RS10930	COG4574	serine-type endopeptidase inhibitor activity
LGL93_RS10940	COG2246	polysaccharide biosynthetic process
LGL93_RS10955	COG0814	amino acid
LGL93_RS10980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL93_RS10985	COG0596	Alpha beta hydrolase
LGL93_RS10990	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL93_RS10995	COG1169	isochorismate synthase
LGL93_RS11000	COG4575	ribosome binding
LGL93_RS11015	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL93_RS11020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL93_RS11030	COG0839	Belongs to the complex I subunit 6 family
LGL93_RS11035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL93_RS11040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL93_RS11045	COG1034	ATP synthesis coupled electron transport
LGL93_RS11065	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL93_RS11070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL93_RS11075	COG0583	DNA-binding transcription factor activity
LGL93_RS11080	COG0436	Aminotransferase
LGL93_RS11085	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL93_RS11090	COG0471	metal ion transport
LGL93_RS11090	COG0490	domain, Protein
LGL93_RS11100	COG3013	Belongs to the UPF0304 family
LGL93_RS11105	COG3092	negative regulation of chromosome organization
LGL93_RS11115	COG0857	belongs to the CobB CobQ family
LGL93_RS11115	COG0280	phosphate acetyltransferase
LGL93_RS11120	COG1609	Transcriptional regulator
LGL93_RS11135	COG3037	sugar-specific permease SgaT UlaA
LGL93_RS11140	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL93_RS11145	COG0622	Phosphoesterase
LGL93_RS11155	COG0625	glutathione transferase activity
LGL93_RS11160	COG1090	epimerase
LGL93_RS11170	COG4160	amino acid transport
LGL93_RS11175	COG4215	(ABC) transporter
LGL93_RS11190	COG0163	prenyltransferase activity
LGL93_RS11195	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL93_RS11200	COG1286	toxin biosynthetic process
LGL93_RS11205	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL93_RS11210	COG0285	dihydrofolate synthase activity
LGL93_RS11220	COG0586	Pfam SNARE associated Golgi protein
LGL93_RS11230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL93_RS11255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL93_RS11260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL93_RS11290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL93_RS11305	COG3101	peptidyl-lysine hydroxylation
LGL93_RS11310	COG0730	response to heat
LGL93_RS11315	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL93_RS11325	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL93_RS11330	COG2840	Smr protein MutS2
LGL93_RS11335	COG2062	phosphohistidine phosphatase, SixA
LGL93_RS11345	COG0183	Belongs to the thiolase family
LGL93_RS11350	COG3691	Protein conserved in bacteria
LGL93_RS11365	COG4235	cytochrome complex assembly
LGL93_RS11365	COG3088	subunit of a heme lyase
LGL93_RS11370	COG3088	subunit of a heme lyase
LGL93_RS11370	COG4235	cytochrome complex assembly
LGL93_RS11375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL93_RS11380	COG1138	Cytochrome C-type biogenesis protein
LGL93_RS11385	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL93_RS11390	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL93_RS11395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL93_RS11400	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL93_RS11420	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL93_RS11425	COG2951	lytic endotransglycosylase activity
LGL93_RS11430	COG1598	PFAM Uncharacterised protein family UPF0150
LGL93_RS11440	COG3038	cytochrome b561
LGL93_RS11445	COG0436	Aminotransferase
LGL93_RS11455	COG3275	phosphorelay sensor kinase activity
LGL93_RS11460	COG3279	Response regulator of the LytR AlgR family
LGL93_RS11465	COG2223	nitrite transmembrane transporter activity
LGL93_RS11470	COG0837	glucose binding
LGL93_RS11490	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL93_RS11495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL93_RS11555	COG3530	Putative quorum-sensing-regulated virulence factor
LGL93_RS11560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL93_RS11570	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL93_RS11580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL93_RS11595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL93_RS11605	COG4208	sulfate ABC transporter
LGL93_RS11610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL93_RS11615	COG4150	thiosulfate binding
LGL93_RS11625	COG1737	Transcriptional regulator
LGL93_RS11630	COG2731	YhcH YjgK YiaL family protein
LGL93_RS11645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL93_RS11650	COG2837	iron assimilation
LGL93_RS11660	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL93_RS11765	COG1671	Belongs to the UPF0178 family
LGL93_RS11770	COG0280	phosphate acetyltransferase
LGL93_RS11770	COG0281	malic enzyme
LGL93_RS11775	COG0494	nUDIX hydrolase
LGL93_RS11780	COG3005	denitrification pathway
LGL93_RS11785	COG3043	anaerobic respiration
LGL93_RS11790	COG0243	molybdopterin cofactor binding
LGL93_RS11795	COG3062	negative regulation of establishment of protein localization
LGL93_RS11800	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL93_RS11800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL93_RS11805	COG2197	response regulator
LGL93_RS11815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL93_RS11825	COG1605	Chorismate mutase
LGL93_RS11830	COG1393	Belongs to the ArsC family
LGL93_RS11835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL93_RS11840	COG1876	peptidase activity
LGL93_RS11850	COG0400	carboxylic ester hydrolase activity
LGL93_RS11870	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL93_RS11875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL93_RS11880	COG2716	regulation of RNA biosynthetic process
LGL93_RS11885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL93_RS11890	COG0628	permease
LGL93_RS11895	COG4783	chaperone-mediated protein folding
LGL93_RS11900	COG1393	Belongs to the ArsC family
LGL93_RS11905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL93_RS11910	COG2233	PERMEase
LGL93_RS11915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL93_RS11920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL93_RS11925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL93_RS11930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL93_RS11940	COG0581	inorganic phosphate transmembrane transporter activity
LGL93_RS11945	COG0573	inorganic phosphate transmembrane transporter activity
LGL93_RS11950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL93_RS11965	COG2239	Acts as a magnesium transporter
LGL93_RS11970	COG0443	Heat shock 70 kDa protein
LGL93_RS11980	COG3121	Chaperone
LGL93_RS11995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL93_RS12005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL93_RS12010	COG0477	Major facilitator Superfamily
LGL93_RS12015	COG2205	protein histidine kinase activity
LGL93_RS12020	COG0745	RESPONSE REGULATOR receiver
LGL93_RS12025	COG3422	double-strand break repair
LGL93_RS12030	COG0826	peptidase U32
LGL93_RS12035	COG1597	lipid kinase activity
LGL93_RS12050	COG0351	phosphomethylpyrimidine kinase
LGL93_RS12065	COG0519	Catalyzes the synthesis of GMP from XMP
LGL93_RS12065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL93_RS12070	COG0517	IMP dehydrogenase activity
LGL93_RS12070	COG0516	GMP reductase activity
LGL93_RS12075	COG1570	exodeoxyribonuclease VII activity
LGL93_RS12080	COG1645	bacterial-type flagellum-dependent swarming motility
LGL93_RS12090	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL93_RS12095	COG2976	Protein conserved in bacteria
LGL93_RS12100	COG0124	histidyl-tRNA synthetase
LGL93_RS12120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL93_RS12135	COG4953	penicillin-binding protein 1C
LGL93_RS12140	COG2373	Large extracellular alpha-helical protein
LGL93_RS12155	COG2975	iron-sulfur cluster assembly
LGL93_RS12160	COG0633	Ferredoxin
LGL93_RS12165	COG0443	Heat shock 70 kDa protein
LGL93_RS12180	COG0822	iron-sulfur transferase activity
LGL93_RS12190	COG1959	2 iron, 2 sulfur cluster binding
LGL93_RS12195	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL93_RS12205	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL93_RS12210	COG3683	transport system, periplasmic component
LGL93_RS12215	COG3711	transcriptional antiterminator
LGL93_RS12220	COG2814	Major facilitator Superfamily
LGL93_RS12230	COG1017	nitric oxide dioxygenase activity
LGL93_RS12230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL93_RS12235	COG2188	Transcriptional regulator
LGL93_RS12245	COG3457	Alanine racemase
LGL93_RS12250	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL93_RS12265	COG0347	Belongs to the P(II) protein family
LGL93_RS12270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL93_RS12270	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL93_RS12275	COG2204	response regulator
LGL93_RS12280	COG3170	Tfp pilus assembly protein FimV
LGL93_RS12285	COG2205	protein histidine kinase activity
LGL93_RS12300	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL93_RS12310	COG0560	Phosphoserine phosphatase
LGL93_RS12315	COG1263	PTS System
LGL93_RS12315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL93_RS12325	COG1737	Transcriptional regulator
LGL93_RS12330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL93_RS12340	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL93_RS12350	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL93_RS12365	COG0481	GTPase activity
LGL93_RS12370	COG3086	response to oxidative stress
LGL93_RS12380	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL93_RS12390	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL93_RS12400	COG0513	Belongs to the DEAD box helicase family
LGL93_RS12415	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL93_RS12425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL93_RS12430	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL93_RS12435	COG0497	DNA recombination
LGL93_RS12440	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL93_RS12450	COG2867	negative regulation of translational initiation
LGL93_RS12455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL93_RS12465	COG0582	viral genome integration into host DNA
LGL93_RS12550	COG2963	transposase activity
LGL93_RS12560	COG1069	ribulokinase activity
LGL93_RS12570	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL93_RS12575	COG1129	ABC transporter
LGL93_RS12595	COG1620	l-lactate permease
LGL93_RS12600	COG1304	FMN binding
LGL93_RS12605	COG0579	oxidoreductase
LGL93_RS12610	COG1278	Cold shock
LGL93_RS12640	COG1780	Probably involved in ribonucleotide reductase function
LGL93_RS12645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL93_RS12655	COG4175	Glycine betaine
LGL93_RS12660	COG4176	ABC-type proline glycine betaine transport system permease component
LGL93_RS12665	COG2113	Glycine betaine
LGL93_RS12680	COG1846	Transcriptional regulator
LGL93_RS12690	COG1566	PFAM secretion protein HlyD family protein
LGL93_RS12695	COG2814	Major facilitator Superfamily
LGL93_RS12700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL93_RS12705	COG3118	belongs to the thioredoxin family
LGL93_RS12710	COG3148	PFAM DTW domain containing protein
LGL93_RS12715	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL93_RS12715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL93_RS12715	COG1042	CoA-binding domain protein
LGL93_RS12720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL93_RS12725	COG5544	Lipoprotein
LGL93_RS12750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL93_RS12760	COG2011	ABC-type metal ion transport system permease component
LGL93_RS12765	COG1464	Belongs to the NlpA lipoprotein family
LGL93_RS12775	COG1720	tRNA m6t6A37 methyltransferase activity
LGL93_RS12780	COG0442	prolyl-tRNA aminoacylation
LGL93_RS12785	COG3015	lipoprotein NlpE involved in copper resistance
LGL93_RS12795	COG4681	YaeQ
LGL93_RS12805	COG4568	rho-dependent transcription termination
LGL93_RS12820	COG0346	lactoylglutathione lyase activity
LGL93_RS12835	COG0825	malonyl-CoA metabolic process
LGL93_RS12840	COG0587	DNA-directed DNA polymerase activity
LGL93_RS12845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL93_RS12865	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL93_RS12870	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL93_RS12880	COG0750	zinc metalloprotease
LGL93_RS12885	COG0575	Belongs to the CDS family
LGL93_RS12905	COG0528	UMP kinase activity
LGL93_RS12910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL93_RS12930	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL93_RS12935	COG2171	N-acyltransferase activity
LGL93_RS12950	COG0564	pseudouridine synthase activity
LGL93_RS12955	COG3098	single-species biofilm formation
LGL93_RS12970	COG1611	Belongs to the LOG family
LGL93_RS12980	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL93_RS12985	COG2363	Small membrane protein
LGL93_RS12990	COG0583	DNA-binding transcription factor activity
LGL93_RS13000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL93_RS13005	COG2166	iron-sulfur cluster assembly
LGL93_RS13010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL93_RS13015	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL93_RS13035	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL93_RS13040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL93_RS13040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL93_RS13045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL93_RS13050	COG1074	ATP-dependent DNA helicase activity
LGL93_RS13055	COG1025	Belongs to the peptidase M16 family
LGL93_RS13060	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL93_RS13065	COG4967	type IV pilus modification protein PilV
LGL93_RS13090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL93_RS13095	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL93_RS13105	COG3066	DNA modification
LGL93_RS13110	COG0861	Integral membrane protein TerC family
LGL93_RS13115	COG0667	Aldo Keto reductase
LGL93_RS13120	COG0477	Major facilitator Superfamily
LGL93_RS13125	COG0318	PFAM AMP-dependent synthetase and ligase
LGL93_RS13125	COG0204	Acyl-transferase
LGL93_RS13130	COG1609	Transcriptional regulator
LGL93_RS13140	COG0583	DNA-binding transcription factor activity
LGL93_RS13145	COG0583	DNA-binding transcription factor activity
LGL93_RS13190	COG4795	General secretion pathway protein
LGL93_RS13205	COG2165	general secretion pathway protein
LGL93_RS13215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL93_RS13245	COG1127	ABC transporter
LGL93_RS13250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL93_RS13295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL93_RS13305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL93_RS13310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL93_RS13315	COG4974	Belongs to the 'phage' integrase family
LGL93_RS13320	COG0716	FMN binding
LGL93_RS13330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL93_RS13340	COG1272	protein, Hemolysin III
LGL93_RS13360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL93_RS13365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL93_RS13370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL93_RS13375	COG0006	proline dipeptidase activity
LGL93_RS13385	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL93_RS13395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL93_RS13400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL93_RS13405	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL93_RS13420	COG1279	arginine transmembrane transporter activity
LGL93_RS13430	COG0191	fructose-bisphosphate aldolase activity
LGL93_RS13435	COG0126	phosphoglycerate kinase activity
LGL93_RS13440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL93_RS13445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL93_RS13455	COG1166	arginine decarboxylase activity
LGL93_RS13460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL93_RS13475	COG0640	Transcriptional regulator
LGL93_RS13480	COG3091	SprT-like family
LGL93_RS13485	COG2356	endonuclease I
LGL93_RS13490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL93_RS13495	COG0189	ligase activity
LGL93_RS13500	COG1678	Uncharacterized ACR, COG1678
LGL93_RS13505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL93_RS13510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL93_RS13520	COG2805	Type II/IV secretion system protein
LGL93_RS13525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL93_RS13530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL93_RS13535	COG0762	integral membrane protein
LGL93_RS13540	COG1872	DUF167
LGL93_RS13545	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL93_RS13550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL93_RS13565	COG3171	Protein conserved in bacteria
LGL93_RS13575	COG1194	a g-specific adenine glycosylase
LGL93_RS13580	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL93_RS13585	COG0741	lytic transglycosylase activity
LGL93_RS13595	COG0582	viral genome integration into host DNA
LGL93_RS13620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LGL93_RS13675	COG3596	GTP binding
LGL93_RS13760	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL93_RS13765	COG1882	Formate acetyltransferase
LGL93_RS13770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL93_RS13775	COG0814	amino acid
LGL93_RS13790	COG1028	Short-chain dehydrogenase reductase Sdr
LGL93_RS13795	COG3433	isochorismatase activity
LGL93_RS13795	COG1535	isochorismatase
LGL93_RS13800	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL93_RS13805	COG1169	isochorismate synthase
LGL93_RS13810	COG4592	Periplasmic binding protein
LGL93_RS13820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL93_RS13825	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL93_RS13830	COG1120	ATPase activity
LGL93_RS13840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL93_RS13845	COG3251	PFAM MbtH domain protein
LGL93_RS13855	COG4774	siderophore transport
LGL93_RS13860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL93_RS13885	COG4964	Belongs to the GSP D family
LGL93_RS13935	COG0848	biopolymer transport protein
LGL93_RS13940	COG0811	peptide transport
LGL93_RS13945	COG0626	cystathionine gamma-synthase activity
LGL93_RS13950	COG0586	Pfam SNARE associated Golgi protein
LGL93_RS13955	COG2207	Transcriptional regulator
LGL93_RS13960	COG1979	alcohol dehydrogenase
LGL93_RS13965	COG0656	L-ascorbic acid biosynthetic process
LGL93_RS13975	COG2132	Multicopper oxidase
LGL93_RS13985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGL93_RS13990	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL93_RS13995	COG0583	DNA-binding transcription factor activity
LGL93_RS14000	COG0187	DNA topoisomerase II activity
LGL93_RS14005	COG3150	esterase
LGL93_RS14015	COG3151	Protein conserved in bacteria
LGL93_RS14020	COG0494	nUDIX hydrolase
LGL93_RS14025	COG1538	Outer membrane efflux protein
LGL93_RS14030	COG5463	Belongs to the UPF0441 family
LGL93_RS14035	COG0754	glutathionylspermidine amidase activity
LGL93_RS14040	COG3384	dioxygenase
LGL93_RS14045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL93_RS14055	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL93_RS14055	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL93_RS14065	COG3025	triphosphatase activity
LGL93_RS14070	COG4991	sh3 domain protein
LGL93_RS14075	COG0617	tRNA 3'-terminal CCA addition
LGL93_RS14080	COG1968	undecaprenyl-diphosphatase activity
LGL93_RS14085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL93_RS14090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL93_RS14095	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL93_RS14100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL93_RS14105	COG0358	DNA primase activity
LGL93_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
LGL93_RS14165	COG0463	Glycosyl transferase, family 2
LGL93_RS14230	COG3210	domain, Protein
LGL93_RS14235	COG2831	hemolysin activation secretion protein
LGL93_RS14240	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL93_RS14240	COG1902	pentaerythritol trinitrate reductase activity
LGL93_RS14255	COG1451	nucleotide metabolic process
LGL93_RS14260	COG0673	inositol 2-dehydrogenase activity
LGL93_RS14265	COG0861	Integral membrane protein TerC family
LGL93_RS14270	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL93_RS14280	COG2721	sulfolactate sulfo-lyase activity
LGL93_RS14295	COG2271	Major facilitator Superfamily
LGL93_RS14310	COG0586	Pfam SNARE associated Golgi protein
LGL93_RS14325	COG4575	ribosome binding
LGL93_RS14330	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL93_RS14340	COG2259	Doxx family
LGL93_RS14345	COG0583	DNA-binding transcription factor activity
LGL93_RS14350	COG1741	Belongs to the pirin family
LGL93_RS14365	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL93_RS14380	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL93_RS14385	COG2823	Periplasmic or secreted lipoprotein
LGL93_RS14390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL93_RS14395	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL93_RS14400	COG5002	protein histidine kinase activity
LGL93_RS14400	COG2198	Histidine kinase
LGL93_RS14400	COG0784	Response regulator, receiver
LGL93_RS14410	COG1242	4 iron, 4 sulfur cluster binding
LGL93_RS14415	COG0067	glutamate synthase
LGL93_RS14415	COG0070	glutamate synthase
LGL93_RS14415	COG0069	glutamate synthase activity
LGL93_RS14420	COG0493	'glutamate synthase
LGL93_RS14430	COG2969	positive regulation of protein catabolic process
LGL93_RS14435	COG0625	glutathione transferase activity
LGL93_RS14440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL93_RS14445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL93_RS14450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL93_RS14455	COG3105	Protein conserved in bacteria
LGL93_RS14460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL93_RS14470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL93_RS14475	COG5007	Belongs to the BolA IbaG family
LGL93_RS14480	COG3113	response to antibiotic
LGL93_RS14485	COG2854	intermembrane phospholipid transfer
LGL93_RS14490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL93_RS14495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL93_RS14500	COG1127	ABC transporter
LGL93_RS14505	COG0530	calcium, potassium:sodium antiporter activity
LGL93_RS14510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL93_RS14510	COG0517	IMP dehydrogenase activity
LGL93_RS14515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL93_RS14520	COG3117	lipopolysaccharide transmembrane transporter activity
LGL93_RS14525	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL93_RS14530	COG1137	ATPase activity
LGL93_RS14535	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL93_RS14555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL93_RS14560	COG0540	Belongs to the ATCase OTCase family
LGL93_RS14565	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL93_RS14575	COG0366	Alpha amylase catalytic
LGL93_RS14580	COG1263	PTS System
LGL93_RS14580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL93_RS14590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL93_RS14600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL93_RS14605	COG3783	Cytochrome b(562)
LGL93_RS14610	COG0312	modulator of DNA gyrase
LGL93_RS14615	COG3028	Belongs to the UPF0307 family
LGL93_RS14620	COG2732	(Barnase) inhibitor
LGL93_RS14625	COG4290	ribonuclease
LGL93_RS14635	COG1289	transmembrane transporter activity
LGL93_RS14640	COG1566	PFAM secretion protein HlyD family protein
LGL93_RS14650	COG0583	DNA-binding transcription factor activity
LGL93_RS14655	COG0312	modulator of DNA gyrase
LGL93_RS14660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL93_RS14665	COG3164	Protein of unknown function
LGL93_RS14675	COG0424	maF-like protein
LGL93_RS14680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL93_RS14685	COG1792	Involved in formation and maintenance of cell shape
LGL93_RS14690	COG1077	Cell shape determining protein MreB Mrl
LGL93_RS14695	COG2200	EAL domain
LGL93_RS14695	COG2199	diguanylate cyclase activity
LGL93_RS14700	COG0604	alcohol dehydrogenase
LGL93_RS14705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL93_RS14710	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL93_RS14720	COG0511	ligase activity, forming carbon-carbon bonds
LGL93_RS14725	COG0439	Biotin carboxylase
LGL93_RS14730	COG3924	membrane
LGL93_RS14735	COG4145	pantothenate transmembrane transporter activity
LGL93_RS14740	COG2264	protein methyltransferase activity
LGL93_RS14745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL93_RS14750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL93_RS14760	COG1560	Kdo2-lipid A biosynthetic process
LGL93_RS14770	COG1346	cytolysis
LGL93_RS14775	COG1380	Effector of murein hydrolase LrgA
LGL93_RS14780	COG0583	DNA-binding transcription factor activity
LGL93_RS14785	COG0025	NhaP-type Na H and K H
LGL93_RS14790	COG2252	PERMEase
LGL93_RS14805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL93_RS14810	COG2315	Protein conserved in bacteria
LGL93_RS14815	COG1448	Aminotransferase
LGL93_RS14830	COG0604	alcohol dehydrogenase
LGL93_RS14840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL93_RS14845	COG0735	belongs to the Fur family
LGL93_RS14850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL93_RS14855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL93_RS14860	COG2937	Belongs to the GPAT DAPAT family
LGL93_RS14880	COG4580	involved in the transport of maltose and maltodextrins
LGL93_RS14895	COG2182	Extracellular solute-binding protein
LGL93_RS14900	COG1175	transmembrane transport
LGL93_RS14905	COG3833	ABC-type maltose transport systems, permease component
LGL93_RS14910	COG3223	Belongs to the PsiE family
LGL93_RS14920	COG0527	aspartate kinase activity
LGL93_RS14935	COG3328	transposase activity
LGL93_RS14960	COG1222	aaa ATPase
LGL93_RS15050	COG0583	DNA-binding transcription factor activity
LGL93_RS15090	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL93_RS15130	COG0138	bifunctional purine biosynthesis protein purh
LGL93_RS15135	COG0151	Belongs to the GarS family
LGL93_RS15155	COG1515	deoxyribonuclease V activity
LGL93_RS15160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL93_RS15165	COG2816	NAD+ diphosphatase activity
LGL93_RS15170	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL93_RS15185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL93_RS15190	COG2104	thiamine diphosphate biosynthetic process
LGL93_RS15195	COG2022	thiamine diphosphate biosynthetic process
LGL93_RS15205	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL93_RS15210	COG0085	RNA polymerase activity
LGL93_RS15215	COG0222	ribosome binding
LGL93_RS15220	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL93_RS15230	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL93_RS15235	COG0250	Participates in transcription elongation, termination and antitermination
LGL93_RS15280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL93_RS15305	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL93_RS15310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL93_RS15315	COG1739	Uncharacterized protein family UPF0029
LGL93_RS15325	COG1024	Enoyl-CoA hydratase
LGL93_RS15325	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL93_RS15335	COG0543	2 iron, 2 sulfur cluster binding
LGL93_RS15350	COG0250	Participates in transcription elongation, termination and antitermination
LGL93_RS15365	COG0805	protein transport
LGL93_RS15370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL93_RS15375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL93_RS15380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL93_RS15385	COG3165	ubiquinone biosynthetic process from chorismate
LGL93_RS15390	COG2226	methyltransferase
LGL93_RS15395	COG1322	Protein conserved in bacteria
LGL93_RS15400	COG0586	Pfam SNARE associated Golgi protein
LGL93_RS15405	COG1966	Carbon starvation protein
LGL93_RS15420	COG0412	Dienelactone hydrolase
LGL93_RS15425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL93_RS15430	COG0583	DNA-binding transcription factor activity
LGL93_RS15435	COG0697	spore germination
LGL93_RS15445	COG0584	glycerophosphoryl diester phosphodiesterase
LGL93_RS15455	COG0395	ABC-type sugar transport system, permease component
LGL93_RS15460	COG1175	transmembrane transport
LGL93_RS15465	COG1653	transport
LGL93_RS15500	COG0410	ABC transporter
LGL93_RS15510	COG4177	L-phenylalanine transmembrane transporter activity
LGL93_RS15530	COG1929	Belongs to the glycerate kinase type-1 family
LGL93_RS15535	COG2610	gluconate transmembrane transporter activity
LGL93_RS15540	COG3835	regulator
LGL93_RS15550	COG2177	Part of the ABC transporter FtsEX involved in
LGL93_RS15555	COG2884	Cell division ATP-binding protein ftsE
LGL93_RS15560	COG0552	protein localization to endoplasmic reticulum
LGL93_RS15560	COG0552	protein localization to endoplasmic reticulum
LGL93_RS15565	COG0742	ribosomal rna small subunit methyltransferase
LGL93_RS15570	COG3776	membrane
LGL93_RS15585	COG3714	YhhN family
LGL93_RS15600	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL93_RS15610	COG0247	lactate metabolic process
LGL93_RS15620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL93_RS15630	COG2271	Major facilitator Superfamily
LGL93_RS15635	COG0584	glycerophosphoryl diester phosphodiesterase
LGL93_RS15640	COG0561	phosphatase activity
LGL93_RS15645	COG2267	carboxylic ester hydrolase activity
LGL93_RS15650	COG1280	lysine exporter protein (LysE YggA)
LGL93_RS15655	COG0514	ATP-dependent DNA helicase (RecQ)
LGL93_RS15660	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL93_RS15665	COG2050	protein possibly involved in aromatic compounds catabolism
LGL93_RS15685	COG5564	TIM-barrel signal transduction protein
LGL93_RS15690	COG5441	Belongs to the UPF0261 family
LGL93_RS15700	COG0210	DNA helicase
LGL93_RS15705	COG1011	Hydrolase
LGL93_RS15710	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL93_RS15715	COG3159	Protein conserved in bacteria
LGL93_RS15720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL93_RS15725	COG5567	small periplasmic lipoprotein
LGL93_RS15735	COG3072	Adenylate cyclase
LGL93_RS15740	COG0181	hydroxymethylbilane synthase activity
LGL93_RS15745	COG1587	Uroporphyrinogen-III synthase
LGL93_RS15750	COG2959	enzyme of heme biosynthesis
LGL93_RS15755	COG3071	HemY protein
LGL93_RS15805	COG2244	polysaccharide biosynthetic process
LGL93_RS15810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL93_RS15815	COG0456	acetyltransferase
LGL93_RS15820	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL93_RS15825	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL93_RS15830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL93_RS15835	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL93_RS15840	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL93_RS15845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL93_RS15850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL93_RS15855	COG3118	belongs to the thioredoxin family
LGL93_RS15865	COG0248	Ppx GppA phosphatase
LGL93_RS15875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL93_RS15890	COG3397	chitin binding
LGL93_RS15900	COG0129	dihydroxy-acid dehydratase activity
LGL93_RS15910	COG3978	acetolactate synthase activity
LGL93_RS15930	COG3085	chromosome segregation
LGL93_RS15935	COG0583	DNA-binding transcription factor activity
LGL93_RS16015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL93_RS16025	COG0678	peroxiredoxin activity
LGL93_RS16025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL93_RS16030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL93_RS16065	COG1629	transport
LGL93_RS16070	COG0165	Argininosuccinate lyase
LGL93_RS16075	COG0137	argininosuccinate synthase activity
LGL93_RS16080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL93_RS16125	COG0527	aspartate kinase activity
LGL93_RS16125	COG0460	homoserine dehydrogenase
LGL93_RS16130	COG0626	cystathionine gamma-synthase activity
LGL93_RS16135	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL93_RS16145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL93_RS16150	COG1609	Transcriptional regulator
LGL93_RS16155	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL93_RS16160	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL93_RS16165	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL93_RS16170	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL93_RS16175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL93_RS16180	COG3074	FtsZ-dependent cytokinesis
LGL93_RS16185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL93_RS16190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL93_RS16195	COG1494	fructose-1,6-bisphosphatase
LGL93_RS16200	COG2814	Major facilitator Superfamily
LGL93_RS16210	COG3152	Membrane
LGL93_RS16225	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL93_RS16235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL93_RS16240	COG3678	ATP-independent chaperone mediated protein folding
LGL93_RS16245	COG0745	RESPONSE REGULATOR receiver
LGL93_RS16250	COG2205	protein histidine kinase activity
LGL93_RS16255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL93_RS16260	COG1045	serine acetyltransferase
LGL93_RS16265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL93_RS16270	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL93_RS16275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL93_RS16280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL93_RS16285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL93_RS16290	COG4942	peptidase
LGL93_RS16295	COG2861	carbohydrate metabolic process
LGL93_RS16310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL93_RS16315	COG0859	PFAM glycosyl transferase family 9
LGL93_RS16320	COG0859	PFAM glycosyl transferase family 9
LGL93_RS16325	COG1519	Transferase
LGL93_RS16345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL93_RS16350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL93_RS16355	COG2003	Belongs to the UPF0758 family
LGL93_RS16360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL93_RS16365	COG0756	dUTP diphosphatase activity
LGL93_RS16370	COG1309	transcriptional regulator
LGL93_RS16375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL93_RS16380	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL93_RS16385	COG1561	YicC-like family, N-terminal region
LGL93_RS16400	COG5001	Diguanylate cyclase
LGL93_RS16405	COG1024	Enoyl-CoA hydratase
LGL93_RS16410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL93_RS16425	COG2860	membrane
LGL93_RS16430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL93_RS16440	COG1758	RNA polymerase activity
LGL93_RS16445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL93_RS16450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL93_RS16455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL93_RS16460	COG0786	glutamate:sodium symporter activity
LGL93_RS16465	COG2233	PERMEase
LGL93_RS16470	COG2982	Protein involved in outer membrane biogenesis
LGL93_RS16475	COG0456	acetyltransferase
LGL93_RS16490	COG1011	Hydrolase
LGL93_RS16505	COG3852	Histidine kinase
LGL93_RS16515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL93_RS16525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL93_RS16530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL93_RS16530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL93_RS16535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL93_RS16540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL93_RS16545	COG3084	Protein conserved in bacteria
LGL93_RS16555	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL93_RS16580	COG2186	Transcriptional regulator
LGL93_RS16585	COG1609	Transcriptional regulator
LGL93_RS16590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL93_RS16600	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL93_RS16605	COG1129	ABC transporter
LGL93_RS16610	COG1869	D-ribose catabolic process
LGL93_RS16615	COG3158	transport of potassium into the cell
LGL93_RS16620	COG0714	Associated with various cellular activities
LGL93_RS16625	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL93_RS16635	COG2502	aspartate--ammonia ligase
LGL93_RS16640	COG1522	sequence-specific DNA binding
LGL93_RS16645	COG0716	FMN binding
LGL93_RS16650	COG0445	tRNA wobble uridine modification
LGL93_RS16655	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL93_RS16660	COG3312	ion transport
LGL93_RS16665	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL93_RS16675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL93_RS16685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL93_RS16690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL93_RS16700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL93_RS16715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL93_RS16720	COG0573	inorganic phosphate transmembrane transporter activity
LGL93_RS16725	COG0581	inorganic phosphate transmembrane transporter activity
LGL93_RS16735	COG0704	Plays a role in the regulation of phosphate uptake
LGL93_RS16740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL93_RS16745	COG0765	amino acid transport
LGL93_RS16750	COG0765	amino acid transport
LGL93_RS16755	COG2252	PERMEase
LGL93_RS16760	COG0840	transmembrane signaling receptor activity
LGL93_RS16770	COG3121	Chaperone
LGL93_RS16785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL93_RS16790	COG0706	membrane insertase activity
LGL93_RS16800	COG0594	ribonuclease P activity
LGL93_RS16805	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGL93_RS16935	COG2944	sequence-specific DNA binding
LGL93_RS17110	COG1196	nuclear chromosome segregation
LGL93_RS17230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL93_RS17245	COG0741	lytic transglycosylase activity