locus-tag	class	description
LGL87_RS00010	COG0592	DNA-directed DNA polymerase activity
LGL87_RS00020	COG0187	DNA topoisomerase II activity
LGL87_RS00025	COG0561	phosphatase activity
LGL87_RS00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL87_RS00035	COG5645	(Lipo)protein
LGL87_RS00050	COG0569	domain protein
LGL87_RS00050	COG2985	domain, Protein
LGL87_RS00055	COG3977	Valine--pyruvate aminotransferase
LGL87_RS00060	COG2885	chlorophyll binding
LGL87_RS00085	COG2818	Glycosylase
LGL87_RS00135	COG2213	PTS system mannitol-specific
LGL87_RS00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL87_RS00145	COG3722	fumarate hydratase activity
LGL87_RS00155	COG2258	MOSC domain
LGL87_RS00160	COG0840	transmembrane signaling receptor activity
LGL87_RS00165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL87_RS00180	COG0437	4 iron, 4 sulfur cluster binding
LGL87_RS00185	COG2864	formate dehydrogenase
LGL87_RS00195	COG1921	L-seryl-tRNASec selenium transferase activity
LGL87_RS00200	COG3276	selenocysteine insertion sequence binding
LGL87_RS00205	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL87_RS00215	COG3274	enterobacterial common antigen metabolic process
LGL87_RS00255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL87_RS00260	COG2986	histidine ammonia-lyase
LGL87_RS00280	COG2194	sulfuric ester hydrolase activity
LGL87_RS00285	COG2197	response regulator
LGL87_RS00290	COG3851	Histidine kinase
LGL87_RS00295	COG2271	Major facilitator Superfamily
LGL87_RS00305	COG0747	negative chemotaxis
LGL87_RS00310	COG0601	transmembrane transport
LGL87_RS00315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL87_RS00320	COG0444	Belongs to the ABC transporter superfamily
LGL87_RS00325	COG4608	Belongs to the ABC transporter superfamily
LGL87_RS00330	COG2194	sulfuric ester hydrolase activity
LGL87_RS00355	COG1215	transferase activity, transferring glycosyl groups
LGL87_RS00360	COG1215	transferase activity, transferring glycosyl groups
LGL87_RS00365	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL87_RS00370	COG0457	Tetratricopeptide repeat
LGL87_RS00370	COG3118	belongs to the thioredoxin family
LGL87_RS00375	COG2200	EAL domain
LGL87_RS00375	COG2199	diguanylate cyclase activity
LGL87_RS00380	COG1301	dicarboxylic acid transport
LGL87_RS00385	COG0612	Peptidase, M16
LGL87_RS00390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL87_RS00395	COG1942	4-Oxalocrotonate Tautomerase
LGL87_RS00400	COG2200	EAL domain
LGL87_RS00405	COG2134	cdp-diacylglycerol pyrophosphatase
LGL87_RS00410	COG1295	ribonuclease BN
LGL87_RS00420	COG1301	dicarboxylic acid transport
LGL87_RS00425	COG0626	cystathionine gamma-synthase activity
LGL87_RS00435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL87_RS00440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL87_RS00445	COG0339	signal peptide processing
LGL87_RS00450	COG0742	ribosomal rna small subunit methyltransferase
LGL87_RS00460	COG0589	response to stress
LGL87_RS00470	COG0306	phosphate transporter
LGL87_RS00475	COG2081	HI0933 family
LGL87_RS00520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL87_RS00640	COG1247	-acetyltransferase
LGL87_RS00650	COG1741	Belongs to the pirin family
LGL87_RS00655	COG1609	Transcriptional regulator
LGL87_RS00665	COG3265	gluconokinase activity
LGL87_RS00670	COG2095	MarC family integral membrane protein
LGL87_RS00675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL87_RS00680	COG3275	phosphorelay sensor kinase activity
LGL87_RS00685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL87_RS00690	COG1523	belongs to the glycosyl hydrolase 13 family
LGL87_RS00695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL87_RS00700	COG0297	glycogen (starch) synthase activity
LGL87_RS00705	COG0058	SHG alpha-glucan phosphorylase activity
LGL87_RS00710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL87_RS00715	COG1349	DNA-binding transcription factor activity
LGL87_RS00720	COG0705	Rhomboid family
LGL87_RS00730	COG2909	trisaccharide binding
LGL87_RS00735	COG0058	SHG alpha-glucan phosphorylase activity
LGL87_RS00740	COG1640	4-alpha-glucanotransferase
LGL87_RS00750	COG1040	competence protein
LGL87_RS00755	COG0596	Alpha beta hydrolase
LGL87_RS00775	COG1918	ferrous iron import across plasma membrane
LGL87_RS00780	COG2183	response to ionizing radiation
LGL87_RS00805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL87_RS00820	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL87_RS00830	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL87_RS00835	COG1011	Hydrolase
LGL87_RS00845	COG0494	nUDIX hydrolase
LGL87_RS00850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL87_RS00875	COG4796	Type ii and iii secretion system protein
LGL87_RS00880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL87_RS00900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL87_RS00910	COG0180	Tryptophanyl-tRNA synthetase
LGL87_RS00930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL87_RS00935	COG0402	S-adenosylhomocysteine deaminase activity
LGL87_RS00940	COG0738	Major facilitator superfamily
LGL87_RS00955	COG1609	Transcriptional regulator
LGL87_RS00960	COG1486	melibiose metabolic process
LGL87_RS00965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL87_RS00980	COG1289	transmembrane transporter activity
LGL87_RS00985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL87_RS00990	COG1765	OsmC-like protein
LGL87_RS01015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL87_RS01020	COG3954	Phosphoribulokinase
LGL87_RS01030	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL87_RS01040	COG0859	PFAM glycosyl transferase family 9
LGL87_RS01045	COG1216	Glycosyl transferase, family 2
LGL87_RS01050	COG0488	(ABC) transporter
LGL87_RS01055	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL87_RS01065	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL87_RS01070	COG1047	Peptidyl-prolyl cis-trans
LGL87_RS01080	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL87_RS01085	COG2964	Protein conserved in bacteria
LGL87_RS01095	COG2923	Belongs to the DsrF TusC family
LGL87_RS01100	COG2168	tRNA wobble position uridine thiolation
LGL87_RS01105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL87_RS01110	COG0049	tRNA binding
LGL87_RS01120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL87_RS01135	COG0051	transcription antitermination factor activity, RNA binding
LGL87_RS01140	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL87_RS01150	COG0089	rRNA binding
LGL87_RS01155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL87_RS01160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL87_RS01165	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL87_RS01175	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL87_RS01180	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL87_RS01185	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL87_RS01190	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL87_RS01200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL87_RS01225	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL87_RS01230	COG1841	ribosomal large subunit assembly
LGL87_RS01235	COG0200	Binds to the 23S rRNA
LGL87_RS01240	COG0201	protein transport
LGL87_RS01245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL87_RS01250	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL87_RS01260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL87_RS01270	COG0203	ribosomal protein L17
LGL87_RS01275	COG0789	Transcriptional regulator
LGL87_RS01280	COG3036	rescue of stalled ribosome
LGL87_RS01285	COG1970	mechanosensitive ion channel activity
LGL87_RS01295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL87_RS01295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL87_RS01300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL87_RS01305	COG0242	peptide deformylase activity
LGL87_RS01310	COG0758	DNA mediated transformation
LGL87_RS01315	COG2922	Belongs to the Smg family
LGL87_RS01320	COG0551	DNA topoisomerase type I activity
LGL87_RS01325	COG0009	L-threonylcarbamoyladenylate synthase
LGL87_RS01335	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL87_RS01365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL87_RS01370	COG3162	membrane
LGL87_RS01375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL87_RS01380	COG1301	dicarboxylic acid transport
LGL87_RS01385	COG2391	methyltransferase activity
LGL87_RS01390	COG0425	Belongs to the sulfur carrier protein TusA family
LGL87_RS01400	COG1086	Polysaccharide biosynthesis protein
LGL87_RS01405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL87_RS01410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL87_RS01415	COG2089	acid synthase
LGL87_RS01435	COG2755	lipolytic protein G-D-S-L family
LGL87_RS01435	COG1083	cytidylyl-transferase
LGL87_RS01440	COG1028	Short-chain dehydrogenase reductase Sdr
LGL87_RS01460	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL87_RS01460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL87_RS01465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGL87_RS01485	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL87_RS01505	COG1309	transcriptional regulator
LGL87_RS01510	COG4232	protein-disulfide reductase activity
LGL87_RS01520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL87_RS01550	COG1509	lysine 2,3-aminomutase activity
LGL87_RS01560	COG3397	chitin binding
LGL87_RS01580	COG3188	usher protein
LGL87_RS01600	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL87_RS01605	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL87_RS01610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL87_RS01615	COG1053	succinate dehydrogenase
LGL87_RS01620	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL87_RS01625	COG1511	domain protein
LGL87_RS01625	COG3264	Mechanosensitive ion channel
LGL87_RS01630	COG0688	phosphatidylethanolamine metabolic process
LGL87_RS01635	COG1162	GTPase activity
LGL87_RS01640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL87_RS01660	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL87_RS01665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL87_RS01665	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL87_RS01670	COG0802	atpase or kinase
LGL87_RS01675	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL87_RS01685	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL87_RS01695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL87_RS01700	COG0330	HflC and HflK could
LGL87_RS01705	COG0330	HflC and HflK could
LGL87_RS01710	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL87_RS01715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL87_RS01720	COG1959	2 iron, 2 sulfur cluster binding
LGL87_RS01725	COG0557	exoribonuclease II activity
LGL87_RS01730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL87_RS01750	COG3121	Chaperone
LGL87_RS01755	COG3188	usher protein
LGL87_RS01775	COG1073	alpha beta
LGL87_RS01785	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL87_RS01790	COG2965	DNA replication, synthesis of RNA primer
LGL87_RS01795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL87_RS01800	COG0359	binds to the 23S rRNA
LGL87_RS01805	COG3061	Opacity-associated protein A
LGL87_RS01810	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL87_RS01820	COG0737	Belongs to the 5'-nucleotidase family
LGL87_RS01830	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL87_RS01835	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL87_RS01845	COG1253	flavin adenine dinucleotide binding
LGL87_RS01850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL87_RS01855	COG0729	surface antigen
LGL87_RS01860	COG2911	Protein conserved in bacteria
LGL87_RS01865	COG2105	PFAM AIG2 family protein
LGL87_RS01870	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL87_RS01880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL87_RS01895	COG3423	Transcriptional regulator
LGL87_RS01910	COG0142	geranyltranstransferase activity
LGL87_RS01925	COG0697	spore germination
LGL87_RS01930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL87_RS01935	COG0642	Histidine kinase
LGL87_RS01940	COG0745	RESPONSE REGULATOR receiver
LGL87_RS01945	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL87_RS01955	COG1534	Rna-binding protein
LGL87_RS01960	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL87_RS01970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL87_RS01975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL87_RS01980	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL87_RS02000	COG0195	Participates in both transcription termination and antitermination
LGL87_RS02010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL87_RS02025	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL87_RS02035	COG0513	Belongs to the DEAD box helicase family
LGL87_RS02040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL87_RS02045	COG0814	amino acid
LGL87_RS02055	COG0826	peptidase U32
LGL87_RS02060	COG0826	peptidase U32
LGL87_RS02065	COG3154	lipid carrier protein
LGL87_RS02070	COG3153	acetyltransferase
LGL87_RS02075	COG2827	Endonuclease containing a URI domain
LGL87_RS02080	COG0531	amino acid
LGL87_RS02085	COG1982	Orn Lys Arg decarboxylase major
LGL87_RS02095	COG3787	Belongs to the UPF0306 family
LGL87_RS02100	COG0702	epimerase
LGL87_RS02105	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL87_RS02110	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL87_RS02115	COG3454	Phosphonate metabolism
LGL87_RS02120	COG4778	phosphonate C-P lyase system protein PhnL
LGL87_RS02125	COG4107	phosphonate C-P lyase system protein PhnK
LGL87_RS02130	COG3627	carbon phosphorus lyase activity
LGL87_RS02135	COG3626	phosphonate metabolism
LGL87_RS02140	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL87_RS02145	COG3624	Phosphonate C-P lyase system protein PhnG
LGL87_RS02165	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL87_RS02180	COG2927	DNA polymerase III (CHI subunit)
LGL87_RS02185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL87_RS02190	COG0795	lipopolysaccharide-transporting ATPase activity
LGL87_RS02195	COG0795	lipopolysaccharide-transporting ATPase activity
LGL87_RS02245	COG5492	domain, Protein
LGL87_RS02265	COG3119	arylsulfatase activity
LGL87_RS02270	COG1349	DNA-binding transcription factor activity
LGL87_RS02280	COG2222	sugar isomerase
LGL87_RS02285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL87_RS02290	COG3715	PTS system
LGL87_RS02295	COG3716	PTS system mannose fructose sorbose family IID component
LGL87_RS02305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL87_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
LGL87_RS02325	COG0641	radical SAM
LGL87_RS02330	COG3119	arylsulfatase activity
LGL87_RS02355	COG0859	PFAM glycosyl transferase family 9
LGL87_RS02370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL87_RS02375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL87_RS02385	COG2376	Dihydroxyacetone kinase
LGL87_RS02390	COG1461	Dihydroxyacetone kinase
LGL87_RS02395	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL87_RS02395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL87_RS02395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL87_RS02435	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL87_RS02450	COG2823	Periplasmic or secreted lipoprotein
LGL87_RS02460	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL87_RS02465	COG0084	hydrolase, TatD family'
LGL87_RS02470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL87_RS02485	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL87_RS02495	COG3726	membrane protein affecting hemolysin expression
LGL87_RS02500	COG0560	Phosphoserine phosphatase
LGL87_RS02515	COG0488	(ABC) transporter
LGL87_RS02535	COG0741	lytic transglycosylase activity
LGL87_RS02540	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL87_RS02545	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL87_RS02550	COG0406	alpha-ribazole phosphatase activity
LGL87_RS02555	COG3708	Transcriptional regulator
LGL87_RS02555	COG2207	Transcriptional regulator
LGL87_RS02560	COG3045	CreA protein
LGL87_RS02565	COG0745	RESPONSE REGULATOR receiver
LGL87_RS02600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL87_RS02605	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL87_RS02610	COG0477	Major facilitator Superfamily
LGL87_RS02620	COG1584	GPR1 FUN34 yaaH family protein
LGL87_RS02625	COG0443	Heat shock 70 kDa protein
LGL87_RS02635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL87_RS02640	COG0583	DNA-binding transcription factor activity
LGL87_RS02650	COG0196	riboflavin kinase activity
LGL87_RS02660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL87_RS02665	COG1047	Peptidyl-prolyl cis-trans
LGL87_RS02670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL87_RS02685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL87_RS02695	COG2966	Psort location CytoplasmicMembrane, score
LGL87_RS02720	COG2967	ApaG domain
LGL87_RS02725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL87_RS02730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL87_RS02740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL87_RS02750	COG0564	pseudouridine synthase activity
LGL87_RS02755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL87_RS02760	COG0417	DNA replication proofreading
LGL87_RS02765	COG0586	Pfam SNARE associated Golgi protein
LGL87_RS02775	COG1178	ABC-type Fe3 transport system permease component
LGL87_RS02780	COG4143	(ABC) transporter
LGL87_RS02795	COG2814	Major facilitator Superfamily
LGL87_RS02805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL87_RS02810	COG0473	3-isopropylmalate dehydrogenase activity
LGL87_RS02825	COG1022	Amp-dependent synthetase and ligase
LGL87_RS02830	COG0028	Belongs to the TPP enzyme family
LGL87_RS02850	COG0675	Transposase, IS605 OrfB family
LGL87_RS02865	COG0275	rRNA processing
LGL87_RS02870	COG3116	cell division
LGL87_RS02875	COG0768	penicillin binding
LGL87_RS02880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL87_RS02885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL87_RS02900	COG0772	Belongs to the SEDS family
LGL87_RS02905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL87_RS02910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL87_RS02920	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LGL87_RS02925	COG0849	cell division
LGL87_RS02930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL87_RS02955	COG0494	nUDIX hydrolase
LGL87_RS02975	COG0516	GMP reductase activity
LGL87_RS02980	COG1459	type II secretion system
LGL87_RS02985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL87_RS02990	COG4969	Belongs to the N-Me-Phe pilin family
LGL87_RS03005	COG3725	Membrane protein required for beta-lactamase induction
LGL87_RS03010	COG1113	amino acid transport
LGL87_RS03015	COG2186	Transcriptional regulator
LGL87_RS03020	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL87_RS03025	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL87_RS03030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL87_RS03040	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL87_RS03045	COG3112	Uncharacterised protein family (UPF0231)
LGL87_RS03060	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL87_RS03070	COG2132	Multicopper oxidase
LGL87_RS03080	COG0288	reversible hydration of carbon dioxide
LGL87_RS03085	COG1131	(ABC) transporter
LGL87_RS03090	COG0842	Transport permease protein
LGL87_RS03095	COG0726	polysaccharide deacetylase
LGL87_RS03100	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL87_RS03105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL87_RS03110	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL87_RS03115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL87_RS03120	COG0617	tRNA 3'-terminal CCA addition
LGL87_RS03135	COG1489	DNA binding
LGL87_RS03140	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL87_RS03145	COG1643	Atp-dependent helicase
LGL87_RS03150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL87_RS03155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL87_RS03165	COG0316	Belongs to the HesB IscA family
LGL87_RS03170	COG2860	membrane
LGL87_RS03180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL87_RS03185	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL87_RS03190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL87_RS03200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL87_RS03205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL87_RS03210	COG3956	TIGRFAM MazG family protein
LGL87_RS03215	COG0504	CTP synthase activity
LGL87_RS03225	COG0602	queuosine metabolic process
LGL87_RS03230	COG0720	synthase
LGL87_RS03235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL87_RS03245	COG0175	sulfate reduction
LGL87_RS03260	COG2234	aminopeptidase activity
LGL87_RS03265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL87_RS03265	COG1648	precorrin-2 dehydrogenase activity
LGL87_RS03270	COG0175	sulfate reduction
LGL87_RS03275	COG2895	sulfate adenylyltransferase (ATP) activity
LGL87_RS03280	COG0529	Catalyzes the synthesis of activated sulfate
LGL87_RS03290	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL87_RS03300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL87_RS03305	COG0585	pseudouridine synthase activity
LGL87_RS03310	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL87_RS03320	COG1388	LysM domain
LGL87_RS03320	COG4942	peptidase
LGL87_RS03325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL87_RS03330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL87_RS03400	COG0784	Response regulator, receiver
LGL87_RS03400	COG2205	protein histidine kinase activity
LGL87_RS03425	COG0741	lytic transglycosylase activity
LGL87_RS03560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL87_RS03580	COG2963	transposase activity
LGL87_RS03605	COG3397	chitin binding
LGL87_RS03615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL87_RS03660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL87_RS03670	COG3031	protein transport across the cell outer membrane
LGL87_RS03695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL87_RS03695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL87_RS03710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL87_RS03715	COG2137	regulation of response to DNA damage stimulus
LGL87_RS03720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL87_RS03725	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL87_RS03760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL87_RS03765	COG1238	metal cluster binding
LGL87_RS03770	COG2918	glutathione biosynthetic process
LGL87_RS03775	COG1854	S-ribosylhomocysteine lyase activity
LGL87_RS03780	COG4536	flavin adenine dinucleotide binding
LGL87_RS03785	COG4137	Cytochrome C assembly protein
LGL87_RS03790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL87_RS03800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL87_RS03805	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL87_RS03810	COG0335	large ribosomal subunit rRNA binding
LGL87_RS03815	COG3137	Salt-induced outer membrane protein
LGL87_RS03820	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL87_RS03825	COG3279	Response regulator of the LytR AlgR family
LGL87_RS03830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL87_RS03835	COG0287	Prephenate dehydrogenase
LGL87_RS03835	COG1605	Chorismate mutase
LGL87_RS03840	COG0077	Prephenate dehydratase
LGL87_RS03840	COG1605	Chorismate mutase
LGL87_RS03850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL87_RS03855	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL87_RS03860	COG0564	pseudouridine synthase activity
LGL87_RS03865	COG1496	oxidoreductase activity
LGL87_RS03870	COG0542	response to heat
LGL87_RS03905	COG3021	interspecies interaction between organisms
LGL87_RS03910	COG1388	LysM domain
LGL87_RS03910	COG0741	lytic transglycosylase activity
LGL87_RS03920	COG2226	methyltransferase
LGL87_RS03930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL87_RS03940	COG1960	acyl-CoA dehydrogenase activity
LGL87_RS03945	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL87_RS03950	COG0121	glutamine amidotransferase
LGL87_RS03955	COG3034	peptidoglycan biosynthetic process
LGL87_RS03965	COG1805	sodium ion transport
LGL87_RS03970	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL87_RS03975	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL87_RS03980	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL87_RS03990	COG1477	protein flavinylation
LGL87_RS03995	COG2991	Protein conserved in bacteria
LGL87_RS04005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL87_RS04010	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL87_RS04015	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL87_RS04020	COG1073	alpha beta
LGL87_RS04035	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL87_RS04070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL87_RS04090	COG4126	flavin adenine dinucleotide binding
LGL87_RS04100	COG2974	May be involved in recombination
LGL87_RS04105	COG1940	carbohydrate kinase activity
LGL87_RS04110	COG0419	ATPase involved in DNA repair
LGL87_RS04115	COG0420	3'-5' exonuclease activity
LGL87_RS04120	COG0745	RESPONSE REGULATOR receiver
LGL87_RS04125	COG5002	protein histidine kinase activity
LGL87_RS04140	COG1113	amino acid transport
LGL87_RS04145	COG0366	Alpha amylase catalytic
LGL87_RS04150	COG0300	oxidoreductase activity
LGL87_RS04155	COG0450	alkyl hydroperoxide reductase
LGL87_RS04160	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL87_RS04175	COG1862	Preprotein translocase
LGL87_RS04180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL87_RS04185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL87_RS04190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL87_RS04195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL87_RS04195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL87_RS04200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL87_RS04210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL87_RS04215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL87_RS04220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL87_RS04225	COG0142	geranyltranstransferase activity
LGL87_RS04260	COG0693	protein deglycase activity
LGL87_RS04265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL87_RS04270	COG1666	GTP binding
LGL87_RS04275	COG2814	Major facilitator Superfamily
LGL87_RS04285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL87_RS04290	COG1845	cytochrome c oxidase, subunit III
LGL87_RS04295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL87_RS04300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL87_RS04310	COG2223	nitrite transmembrane transporter activity
LGL87_RS04315	COG3056	Lipoprotein
LGL87_RS04320	COG0271	Belongs to the BolA IbaG family
LGL87_RS04330	COG0740	serine-type endopeptidase activity
LGL87_RS04335	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL87_RS04340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL87_RS04345	COG0776	regulation of translation
LGL87_RS04350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL87_RS04355	COG1555	photosystem II stabilization
LGL87_RS04360	COG0824	Thioesterase
LGL87_RS04365	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL87_RS04370	COG4533	DNA binding
LGL87_RS04385	COG1522	sequence-specific DNA binding
LGL87_RS04390	COG1132	(ABC) transporter
LGL87_RS04395	COG1132	(ABC) transporter
LGL87_RS04400	COG0347	Belongs to the P(II) protein family
LGL87_RS04405	COG0004	ammonium transporteR
LGL87_RS04410	COG1946	Acyl-CoA thioesterase
LGL87_RS04415	COG3695	enzyme binding
LGL87_RS04440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL87_RS04445	COG0254	rRNA binding
LGL87_RS04450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL87_RS04455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL87_RS04460	COG1309	transcriptional regulator
LGL87_RS04465	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL87_RS04470	COG1196	nuclear chromosome segregation
LGL87_RS04470	COG3264	Mechanosensitive ion channel
LGL87_RS04485	COG2832	Protein of unknown function (DUF454)
LGL87_RS04490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL87_RS04530	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL87_RS04535	COG0326	Molecular chaperone. Has ATPase activity
LGL87_RS04555	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL87_RS04565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL87_RS04565	COG4651	solute:proton antiporter activity
LGL87_RS04570	COG0737	Belongs to the 5'-nucleotidase family
LGL87_RS04575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL87_RS04580	COG3735	TraB family
LGL87_RS04585	COG2217	Heavy metal translocating P-type atpase
LGL87_RS04590	COG0789	Transcriptional regulator
LGL87_RS04595	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL87_RS04600	COG0330	HflC and HflK could
LGL87_RS04605	COG3118	belongs to the thioredoxin family
LGL87_RS04610	COG0300	oxidoreductase activity
LGL87_RS04615	COG2755	lipolytic protein G-D-S-L family
LGL87_RS04620	COG4181	ATPase activity
LGL87_RS04625	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL87_RS04630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL87_RS04635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL87_RS04640	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL87_RS04645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL87_RS04670	COG3188	usher protein
LGL87_RS04675	COG3121	Chaperone
LGL87_RS04705	COG2501	S4 domain
LGL87_RS04710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL87_RS04720	COG0582	viral genome integration into host DNA
LGL87_RS04740	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LGL87_RS04745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LGL87_RS04760	COG0732	type I restriction modification DNA specificity domain
LGL87_RS04765	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LGL87_RS04795	COG3596	GTP binding
LGL87_RS04825	COG2003	Belongs to the UPF0758 family
LGL87_RS04855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL87_RS04860	COG1393	Belongs to the ArsC family
LGL87_RS04870	COG1022	Amp-dependent synthetase and ligase
LGL87_RS04895	COG3038	cytochrome b561
LGL87_RS04925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL87_RS04935	COG1215	transferase activity, transferring glycosyl groups
LGL87_RS04955	COG3250	beta-galactosidase activity
LGL87_RS04970	COG1309	transcriptional regulator
LGL87_RS05000	COG2197	response regulator
LGL87_RS05005	COG1278	Cold shock
LGL87_RS05025	COG3706	GGDEF domain
LGL87_RS05035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL87_RS05045	COG2921	Belongs to the UPF0250 family
LGL87_RS05050	COG1686	Belongs to the peptidase S11 family
LGL87_RS05055	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL87_RS05060	COG0772	Belongs to the SEDS family
LGL87_RS05065	COG0768	penicillin binding
LGL87_RS05070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL87_RS05075	COG0799	negative regulation of ribosome biogenesis
LGL87_RS05080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL87_RS05085	COG1466	dna polymerase III delta subunit
LGL87_RS05090	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL87_RS05100	COG2888	peptidyl-tyrosine sulfation
LGL87_RS05105	COG1126	abc transporter atp-binding protein
LGL87_RS05110	COG0765	amino acid transport
LGL87_RS05115	COG0765	amino acid transport
LGL87_RS05125	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL87_RS05130	COG4535	Mg2 and Co2 transporter CorC
LGL87_RS05135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL87_RS05140	COG1702	phosphate starvation-inducible protein PhoH
LGL87_RS05145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL87_RS05150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL87_RS05185	COG0367	asparagine synthase
LGL87_RS05190	COG0647	UMP catabolic process
LGL87_RS05195	COG1846	Transcriptional regulator
LGL87_RS05195	COG1940	carbohydrate kinase activity
LGL87_RS05200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL87_RS05210	COG1263	PTS System
LGL87_RS05210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL87_RS05210	COG2190	(PTS) system
LGL87_RS05235	COG0735	belongs to the Fur family
LGL87_RS05245	COG0840	transmembrane signaling receptor activity
LGL87_RS05255	COG0596	Alpha beta hydrolase
LGL87_RS05260	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL87_RS05265	COG0033	Phosphoglucomutase
LGL87_RS05275	COG0745	RESPONSE REGULATOR receiver
LGL87_RS05280	COG2205	protein histidine kinase activity
LGL87_RS05285	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL87_RS05290	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL87_RS05310	COG3272	Protein of unknown function (DUF1722)
LGL87_RS05315	COG0415	Belongs to the DNA photolyase family
LGL87_RS05320	COG5212	phosphodiesterase
LGL87_RS05325	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL87_RS05330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL87_RS05335	COG1984	allophanate hydrolase subunit 2
LGL87_RS05340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL87_RS05375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL87_RS05380	COG1053	succinate dehydrogenase
LGL87_RS05385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL87_RS05390	COG0567	Dehydrogenase, E1 component
LGL87_RS05395	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL87_RS05400	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL87_RS05405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL87_RS05410	COG0737	Belongs to the 5'-nucleotidase family
LGL87_RS05415	COG1271	oxidase subunit
LGL87_RS05420	COG1294	oxidase, subunit
LGL87_RS05425	COG4890	Cyd operon protein YbgT
LGL87_RS05430	COG3790	cyd operon protein YbgE
LGL87_RS05435	COG0824	Thioesterase
LGL87_RS05440	COG0811	peptide transport
LGL87_RS05445	COG0848	biopolymer transport protein
LGL87_RS05450	COG3064	Membrane
LGL87_RS05450	COG3064	Membrane
LGL87_RS05455	COG0823	Involved in the tonB-independent uptake of proteins
LGL87_RS05460	COG2885	chlorophyll binding
LGL87_RS05465	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL87_RS05505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL87_RS05515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL87_RS05515	COG2205	protein histidine kinase activity
LGL87_RS05525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL87_RS05530	COG0588	phosphoglycerate mutase activity
LGL87_RS05540	COG2017	converts alpha-aldose to the beta-anomer
LGL87_RS05550	COG1085	galactose-1-phosphate uridylyltransferase
LGL87_RS05555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL87_RS05570	COG3585	molybdate ion transport
LGL87_RS05570	COG2005	Transcriptional regulator
LGL87_RS05580	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL87_RS05585	COG4149	molybdate abc transporter
LGL87_RS05595	COG0561	phosphatase activity
LGL87_RS05600	COG2706	6-phosphogluconolactonase activity
LGL87_RS05615	COG0156	8-amino-7-oxononanoate synthase activity
LGL87_RS05620	COG2226	methyltransferase
LGL87_RS05635	COG0556	nucleotide-excision repair
LGL87_RS05640	COG4628	conserved protein (DUF2132)
LGL87_RS05655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL87_RS05660	COG1120	ATPase activity
LGL87_RS05665	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL87_RS05670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL87_RS05680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL87_RS05685	COG0314	molybdopterin synthase activity
LGL87_RS05690	COG0670	Belongs to the BI1 family
LGL87_RS05695	COG0842	Transport permease protein
LGL87_RS05700	COG0842	Transport permease protein
LGL87_RS05705	COG1131	(ABC) transporter
LGL87_RS05710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL87_RS05715	COG1309	transcriptional regulator
LGL87_RS05720	COG0513	Belongs to the DEAD box helicase family
LGL87_RS05725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL87_RS05735	COG1686	Belongs to the peptidase S11 family
LGL87_RS05740	COG0277	FAD linked oxidase domain protein
LGL87_RS05760	COG2261	transglycosylase associated protein
LGL87_RS05770	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL87_RS05780	COG3639	organic phosphonate transmembrane transporter activity
LGL87_RS05785	COG4807	Protein conserved in bacteria
LGL87_RS05790	COG2897	thiosulfate sulfurtransferase activity
LGL87_RS05795	COG1732	Glycine betaine
LGL87_RS05800	COG1174	glycine betaine transport
LGL87_RS05805	COG1125	glycine betaine transport
LGL87_RS05810	COG1174	glycine betaine transport
LGL87_RS05815	COG0531	amino acid
LGL87_RS05820	COG1982	Orn Lys Arg decarboxylase major
LGL87_RS05830	COG0697	spore germination
LGL87_RS05845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL87_RS05850	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL87_RS05855	COG1126	abc transporter atp-binding protein
LGL87_RS05860	COG0765	amino acid transport
LGL87_RS05865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL87_RS05880	COG5006	permease, DMT superfamily
LGL87_RS05885	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL87_RS05890	COG2239	Acts as a magnesium transporter
LGL87_RS05895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL87_RS05900	COG0488	(ABC) transporter
LGL87_RS05905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL87_RS05910	COG0303	'Molybdopterin
LGL87_RS05930	COG0583	DNA-binding transcription factor activity
LGL87_RS05935	COG0477	Major facilitator Superfamily
LGL87_RS05940	COG0302	gtp cyclohydrolase
LGL87_RS05945	COG2311	Membrane
LGL87_RS05970	COG2949	membrane
LGL87_RS05975	COG0281	malic enzyme
LGL87_RS05985	COG0583	DNA-binding transcription factor activity
LGL87_RS05995	COG1346	cytolysis
LGL87_RS06000	COG1380	Effector of murein hydrolase LrgA
LGL87_RS06010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL87_RS06010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL87_RS06015	COG0489	protein tyrosine kinase activity
LGL87_RS06020	COG0572	uridine kinase
LGL87_RS06025	COG0717	Belongs to the dCTP deaminase family
LGL87_RS06030	COG2982	Protein involved in outer membrane biogenesis
LGL87_RS06035	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL87_RS06040	COG1253	flavin adenine dinucleotide binding
LGL87_RS06045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL87_RS06050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL87_RS06055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL87_RS06065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL87_RS06065	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL87_RS06075	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL87_RS06085	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL87_RS06085	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL87_RS06090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL87_RS06095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL87_RS06110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL87_RS06115	COG0625	glutathione transferase activity
LGL87_RS06130	COG0626	cystathionine gamma-synthase activity
LGL87_RS06140	COG1686	Belongs to the peptidase S11 family
LGL87_RS06145	COG1760	l-serine dehydratase
LGL87_RS06150	COG0814	amino acid
LGL87_RS06155	COG1349	DNA-binding transcription factor activity
LGL87_RS06165	COG0671	phosphoesterase, PA-phosphatase related
LGL87_RS06215	COG0569	domain protein
LGL87_RS06215	COG2985	domain, Protein
LGL87_RS06235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL87_RS06240	COG3842	ATPase activity
LGL87_RS06245	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL87_RS06265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL87_RS06270	COG4160	amino acid transport
LGL87_RS06275	COG4215	(ABC) transporter
LGL87_RS06280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL87_RS06285	COG1126	abc transporter atp-binding protein
LGL87_RS06295	COG0393	Putative heavy-metal-binding
LGL87_RS06300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL87_RS06305	COG0702	epimerase
LGL87_RS06310	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL87_RS06315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL87_RS06320	COG1151	hydroxylamine reductase activity
LGL87_RS06325	COG2431	L-lysine efflux transmembrane transporter activity
LGL87_RS06330	COG3593	DNA synthesis involved in DNA repair
LGL87_RS06340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL87_RS06350	COG1278	Cold shock
LGL87_RS06355	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL87_RS06360	COG0542	response to heat
LGL87_RS06365	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL87_RS06375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL87_RS06385	COG0492	ferredoxin-NADP+ reductase activity
LGL87_RS06390	COG1522	sequence-specific DNA binding
LGL87_RS06395	COG1674	ftsk spoiiie
LGL87_RS06395	COG3107	peptidoglycan biosynthetic process
LGL87_RS06400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL87_RS06405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL87_RS06410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL87_RS06415	COG2814	Major facilitator Superfamily
LGL87_RS06420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL87_RS06425	COG1882	Formate acetyltransferase
LGL87_RS06430	COG2116	formate transmembrane transporter activity
LGL87_RS06435	COG1944	ATP diphosphatase activity
LGL87_RS06440	COG0252	asparaginase activity
LGL87_RS06450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL87_RS06460	COG0539	negative regulation of cytoplasmic translation
LGL87_RS06470	COG0658	competence protein
LGL87_RS06470	COG2333	competence protein COMEC
LGL87_RS06480	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL87_RS06485	COG5383	Protein conserved in bacteria
LGL87_RS06495	COG1278	Cold shock
LGL87_RS06500	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL87_RS06505	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL87_RS06510	COG3173	Aminoglycoside phosphotransferase
LGL87_RS06515	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL87_RS06520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL87_RS06525	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL87_RS06535	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL87_RS06540	COG2989	Protein conserved in bacteria
LGL87_RS06545	COG3108	Peptidase M15
LGL87_RS06550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL87_RS06555	COG1448	Aminotransferase
LGL87_RS06570	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL87_RS06575	COG0308	aminopeptidase N
LGL87_RS06580	COG0167	dihydroorotate dehydrogenase activity
LGL87_RS06595	COG0116	Belongs to the methyltransferase superfamily
LGL87_RS06595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL87_RS06600	COG0488	(ABC) transporter
LGL87_RS06605	COG2995	paraquat-inducible protein a
LGL87_RS06610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL87_RS06610	COG3008	intermembrane lipid transfer
LGL87_RS06615	COG3009	Protein conserved in bacteria
LGL87_RS06620	COG3130	regulation of translation
LGL87_RS06625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL87_RS06630	COG1067	ATP-dependent peptidase activity
LGL87_RS06635	COG3120	sequence-specific DNA binding
LGL87_RS06645	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL87_RS06650	COG3070	regulator of competence-specific genes
LGL87_RS06655	COG1289	transmembrane transporter activity
LGL87_RS06660	COG3304	Inner membrane component domain
LGL87_RS06665	COG0210	DNA helicase
LGL87_RS06670	COG1803	Methylglyoxal synthase
LGL87_RS06680	COG1832	CoA-binding protein
LGL87_RS06685	COG3785	DNA binding
LGL87_RS06690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL87_RS06695	COG1254	Belongs to the acylphosphatase family
LGL87_RS06700	COG2920	part of a sulfur-relay system
LGL87_RS06710	COG0288	reversible hydration of carbon dioxide
LGL87_RS06730	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL87_RS06735	COG2943	transferase activity, transferring hexosyl groups
LGL87_RS06755	COG1560	Kdo2-lipid A biosynthetic process
LGL87_RS06765	COG0628	permease
LGL87_RS06790	COG0418	dihydroorotase activity
LGL87_RS06795	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGL87_RS06805	COG1530	ribonuclease E activity
LGL87_RS06810	COG0564	pseudouridine synthase activity
LGL87_RS06815	COG0424	maF-like protein
LGL87_RS06820	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL87_RS06825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL87_RS06835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL87_RS06840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL87_RS06850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL87_RS06855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL87_RS06860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL87_RS06865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL87_RS06870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL87_RS06875	COG0470	DNA polymerase III
LGL87_RS06880	COG0084	hydrolase, TatD family'
LGL87_RS06885	COG1263	PTS System
LGL87_RS06885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL87_RS06890	COG0537	adenosine 5'-monophosphoramidase activity
LGL87_RS06895	COG5633	Lipoprotein
LGL87_RS06900	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL87_RS06915	COG3150	esterase
LGL87_RS06920	COG1252	NADH dehydrogenase
LGL87_RS06925	COG3134	Outer membrane lipoprotein
LGL87_RS06930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL87_RS06935	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL87_RS06945	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL87_RS06965	COG2850	peptidyl-arginine hydroxylation
LGL87_RS06970	COG2205	protein histidine kinase activity
LGL87_RS06975	COG0745	RESPONSE REGULATOR receiver
LGL87_RS06985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL87_RS06990	COG2915	High frequency lysogenization protein hflD homolog
LGL87_RS06995	COG0482	sulfurtransferase activity
LGL87_RS07005	COG1187	pseudouridine synthase activity
LGL87_RS07010	COG0538	isocitrate dehydrogenase activity
LGL87_RS07015	COG2771	luxR family
LGL87_RS07020	COG3916	Acyl-homoserine-lactone synthase
LGL87_RS07025	COG2723	6-phospho-beta-galactosidase activity
LGL87_RS07035	COG0339	signal peptide processing
LGL87_RS07040	COG0840	transmembrane signaling receptor activity
LGL87_RS07045	COG3493	citrate carrier protein
LGL87_RS07050	COG4565	transcriptional regulatory protein
LGL87_RS07055	COG3290	protein histidine kinase activity
LGL87_RS07060	COG0471	metal ion transport
LGL87_RS07100	COG4977	sequence-specific DNA binding
LGL87_RS07105	COG1702	phosphate starvation-inducible protein PhoH
LGL87_RS07110	COG0387	Pfam Sodium calcium exchanger
LGL87_RS07115	COG2375	cellular response to nickel ion
LGL87_RS07120	COG3850	Histidine kinase
LGL87_RS07130	COG1294	oxidase, subunit
LGL87_RS07135	COG1271	oxidase subunit
LGL87_RS07140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL87_RS07145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL87_RS07150	COG3138	arginine N-succinyltransferase
LGL87_RS07160	COG3724	N-succinylarginine dihydrolase activity
LGL87_RS07180	COG1228	amidohydrolase
LGL87_RS07190	COG0402	S-adenosylhomocysteine deaminase activity
LGL87_RS07210	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL87_RS07215	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL87_RS07220	COG3383	formate dehydrogenase (NAD+) activity
LGL87_RS07225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL87_RS07230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL87_RS07240	COG3260	NADH ubiquinone oxidoreductase 20
LGL87_RS07245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL87_RS07250	COG3261	NADH dehydrogenase
LGL87_RS07250	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL87_RS07255	COG0650	Formate hydrogenlyase subunit 4
LGL87_RS07260	COG0651	ATP synthesis coupled electron transport
LGL87_RS07265	COG0651	ATP synthesis coupled electron transport
LGL87_RS07270	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL87_RS07280	COG0375	protein maturation
LGL87_RS07285	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL87_RS07290	COG0298	carbon dioxide binding
LGL87_RS07295	COG0409	Hydrogenase expression formation protein
LGL87_RS07300	COG0309	Hydrogenase expression formation protein (HypE)
LGL87_RS07305	COG2963	transposase activity
LGL87_RS07350	COG2207	Transcriptional regulator
LGL87_RS07350	COG3708	Transcriptional regulator
LGL87_RS07355	COG0012	GTP binding
LGL87_RS07365	COG0193	aminoacyl-tRNA hydrolase activity
LGL87_RS07375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL87_RS07385	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL87_RS07390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL87_RS07395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL87_RS07400	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL87_RS07415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL87_RS07420	COG0659	secondary active sulfate transmembrane transporter activity
LGL87_RS07425	COG3706	GGDEF domain
LGL87_RS07450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL87_RS07460	COG3381	protein complex oligomerization
LGL87_RS07480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL87_RS07495	COG0728	peptidoglycan biosynthetic process
LGL87_RS07525	COG3102	Protein conserved in bacteria
LGL87_RS07530	COG3142	Participates in the control of copper homeostasis
LGL87_RS07545	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL87_RS07550	COG1801	Protein of unknown function DUF72
LGL87_RS07560	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL87_RS07565	COG0494	nUDIX hydrolase
LGL87_RS07575	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL87_RS07585	COG2255	four-way junction helicase activity
LGL87_RS07590	COG3104	oligopeptide transport
LGL87_RS07595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL87_RS07600	COG1121	(ABC) transporter
LGL87_RS07605	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL87_RS07610	COG0739	heme binding
LGL87_RS07615	COG1560	Kdo2-lipid A biosynthetic process
LGL87_RS07620	COG0469	pyruvate kinase activity
LGL87_RS07625	COG1737	Transcriptional regulator
LGL87_RS07630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL87_RS07635	COG0800	Aldolase
LGL87_RS07645	COG2076	Multidrug Resistance protein
LGL87_RS07650	COG0251	oxidation-reduction process
LGL87_RS07655	COG1199	ATP-dependent helicase activity
LGL87_RS07660	COG1214	PFAM Peptidase M22, glycoprotease
LGL87_RS07665	COG3065	identical protein binding
LGL87_RS07670	COG0318	PFAM AMP-dependent synthetase and ligase
LGL87_RS07675	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL87_RS07680	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL87_RS07685	COG2894	cell division
LGL87_RS07690	COG0850	regulation of cytokinetic process
LGL87_RS07695	COG3100	YcgL domain-containing protein
LGL87_RS07700	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL87_RS07705	COG2983	Belongs to the UPF0260 family
LGL87_RS07725	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL87_RS07735	COG2719	SpoVR family
LGL87_RS07740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL87_RS07745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL87_RS07750	COG2814	Major facilitator Superfamily
LGL87_RS07760	COG2200	EAL domain
LGL87_RS07760	COG2199	diguanylate cyclase activity
LGL87_RS07760	COG2202	Pas domain
LGL87_RS07780	COG2718	Belongs to the UPF0229 family
LGL87_RS07785	COG2766	serine protein kinase
LGL87_RS07795	COG3713	MltA-interacting MipA family protein
LGL87_RS07800	COG2194	sulfuric ester hydrolase activity
LGL87_RS07815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL87_RS07820	COG3139	Protein of unknown function (DUF1315)
LGL87_RS07825	COG1335	isochorismatase
LGL87_RS07830	COG0252	asparaginase activity
LGL87_RS07835	COG0616	signal peptide processing
LGL87_RS07840	COG0778	Nitroreductase
LGL87_RS07850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL87_RS07860	COG0494	nUDIX hydrolase
LGL87_RS07865	COG0708	Exodeoxyribonuclease III
LGL87_RS07895	COG0788	formyltetrahydrofolate deformylase activity
LGL87_RS07900	COG3012	SEC-C Motif Domain Protein
LGL87_RS07905	COG2963	transposase activity
LGL87_RS07920	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL87_RS07925	COG0745	RESPONSE REGULATOR receiver
LGL87_RS07945	COG1454	alcohol dehydrogenase
LGL87_RS07945	COG1012	belongs to the aldehyde dehydrogenase family
LGL87_RS07955	COG2095	MarC family integral membrane protein
LGL87_RS07960	COG4166	transmembrane transport
LGL87_RS07975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL87_RS07990	COG3099	Belongs to the UPF0263 family
LGL87_RS07995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL87_RS08015	COG2350	Protein conserved in bacteria
LGL87_RS08030	COG3710	Transcriptional regulator
LGL87_RS08065	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL87_RS08090	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL87_RS08095	COG3047	cAMP biosynthetic process
LGL87_RS08110	COG0133	tryptophan synthase activity
LGL87_RS08115	COG0135	phosphoribosylanthranilate isomerase activity
LGL87_RS08115	COG0134	indole-3-glycerol-phosphate synthase activity
LGL87_RS08125	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL87_RS08135	COG0613	PHP domain protein
LGL87_RS08140	COG0009	L-threonylcarbamoyladenylate synthase
LGL87_RS08145	COG1187	pseudouridine synthase activity
LGL87_RS08160	COG0616	signal peptide processing
LGL87_RS08175	COG0583	DNA-binding transcription factor activity
LGL87_RS08190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL87_RS08200	COG0671	phosphoesterase, PA-phosphatase related
LGL87_RS08205	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL87_RS08210	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL87_RS08230	COG0023	Translation Initiation Factor
LGL87_RS08240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL87_RS08245	COG5002	protein histidine kinase activity
LGL87_RS08245	COG5001	Diguanylate cyclase
LGL87_RS08245	COG3447	MASE1 domain protein
LGL87_RS08250	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL87_RS08255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL87_RS08265	COG4659	FMN binding
LGL87_RS08275	COG2207	Transcriptional regulator
LGL87_RS08275	COG3708	Transcriptional regulator
LGL87_RS08290	COG4657	Part of a membrane complex involved in electron transport
LGL87_RS08300	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL87_RS08310	COG0673	inositol 2-dehydrogenase activity
LGL87_RS08315	COG0385	Bile acid
LGL87_RS08320	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL87_RS08325	COG5339	Protein conserved in bacteria
LGL87_RS08330	COG1482	cell wall glycoprotein biosynthetic process
LGL87_RS08335	COG0114	fumarate hydratase activity
LGL87_RS08345	COG1940	carbohydrate kinase activity
LGL87_RS08350	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL87_RS08370	COG1742	UPF0060 membrane protein
LGL87_RS08375	COG4221	oxidoreductase activity
LGL87_RS08380	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL87_RS08400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL87_RS08430	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LGL87_RS08450	COG1011	Hydrolase
LGL87_RS08460	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL87_RS08465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL87_RS08470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL87_RS08475	COG0589	response to stress
LGL87_RS08505	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL87_RS08510	COG3623	hexulose-6-phosphate isomerase
LGL87_RS08515	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL87_RS08520	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL87_RS08530	COG0531	amino acid
LGL87_RS08540	COG0745	RESPONSE REGULATOR receiver
LGL87_RS08545	COG2205	protein histidine kinase activity
LGL87_RS08560	COG2207	Transcriptional regulator
LGL87_RS08565	COG1881	PFAM PEBP family protein
LGL87_RS08575	COG3591	Belongs to the peptidase S1B family
LGL87_RS08580	COG1643	Atp-dependent helicase
LGL87_RS08585	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL87_RS08590	COG3784	Protein of unknown function (DUF1318)
LGL87_RS08605	COG2911	Protein conserved in bacteria
LGL87_RS08610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL87_RS08615	COG3187	Heat shock protein
LGL87_RS08620	COG3042	response to heat
LGL87_RS08625	COG1285	pathogenesis
LGL87_RS08635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL87_RS08635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL87_RS08635	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL87_RS08635	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL87_RS08650	COG4166	transmembrane transport
LGL87_RS08655	COG2866	Carboxypeptidase
LGL87_RS08660	COG4948	Mandelate Racemase Muconate Lactonizing
LGL87_RS08665	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL87_RS08675	COG5642	Protein of unknown function (DUF2384)
LGL87_RS08680	COG5654	RES domain protein
LGL87_RS08685	COG3768	UPF0283 membrane protein
LGL87_RS08690	COG3106	COG3106 Predicted ATPase
LGL87_RS08700	COG1983	PspC domain protein
LGL87_RS08710	COG1842	Phage shock protein A
LGL87_RS08730	COG4166	transmembrane transport
LGL87_RS08740	COG4171	peptide transport system, permease
LGL87_RS08745	COG4172	Belongs to the ABC transporter superfamily
LGL87_RS08750	COG4172	Belongs to the ABC transporter superfamily
LGL87_RS08760	COG3104	oligopeptide transport
LGL87_RS08770	COG0484	heat shock protein binding
LGL87_RS08815	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL87_RS08820	COG3133	Outer membrane lipoprotein
LGL87_RS08835	COG4989	oxidoreductase activity
LGL87_RS08840	COG3313	Fe-S protein
LGL87_RS08845	COG2194	sulfuric ester hydrolase activity
LGL87_RS08850	COG1309	transcriptional regulator
LGL87_RS08855	COG1902	pentaerythritol trinitrate reductase activity
LGL87_RS08870	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL87_RS08875	COG0791	NLP P60 protein
LGL87_RS08880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL87_RS08890	COG1609	Transcriptional regulator
LGL87_RS08895	COG0583	DNA-binding transcription factor activity
LGL87_RS08900	COG2814	Major facilitator Superfamily
LGL87_RS08905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL87_RS08910	COG0307	riboflavin synthase, alpha
LGL87_RS08945	COG1388	LysM domain
LGL87_RS08945	COG1376	ErfK ybiS ycfS ynhG family protein
LGL87_RS08950	COG2166	iron-sulfur cluster assembly
LGL87_RS08960	COG0719	Fe-S assembly protein
LGL87_RS08965	COG0396	ATPase activity
LGL87_RS08970	COG0719	Fe-S assembly protein
LGL87_RS08975	COG0316	Belongs to the HesB IscA family
LGL87_RS08980	COG2050	protein possibly involved in aromatic compounds catabolism
LGL87_RS08985	COG0277	FAD linked oxidase domain protein
LGL87_RS08985	COG0247	lactate metabolic process
LGL87_RS08990	COG0628	permease
LGL87_RS09000	COG0574	Belongs to the PEP-utilizing enzyme family
LGL87_RS09000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL87_RS09005	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL87_RS09010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL87_RS09020	COG4771	TonB-dependent receptor
LGL87_RS09025	COG3720	iron ion transport
LGL87_RS09030	COG4558	Periplasmic binding protein
LGL87_RS09035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL87_RS09040	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL87_RS09050	COG0095	Lipoate-protein ligase
LGL87_RS09055	COG0791	NLP P60 protein
LGL87_RS09060	COG2076	Multidrug Resistance protein
LGL87_RS09065	COG2076	Multidrug Resistance protein
LGL87_RS09070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL87_RS09090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL87_RS09100	COG4139	cobalamin transport
LGL87_RS09145	COG0776	regulation of translation
LGL87_RS09215	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL87_RS09220	COG1121	(ABC) transporter
LGL87_RS09225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL87_RS09230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL87_RS09235	COG3001	Fructosamine kinase
LGL87_RS09245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL87_RS09250	COG1988	membrane-bound metal-dependent
LGL87_RS09255	COG1823	symporter activity
LGL87_RS09260	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL87_RS09270	COG2814	Major facilitator Superfamily
LGL87_RS09280	COG0501	Belongs to the peptidase M48B family
LGL87_RS09285	COG0793	Belongs to the peptidase S41A family
LGL87_RS09295	COG1956	GAF domain-containing protein
LGL87_RS09300	COG2995	paraquat-inducible protein a
LGL87_RS09305	COG3008	intermembrane lipid transfer
LGL87_RS09310	COG2203	Gaf domain
LGL87_RS09310	COG3706	GGDEF domain
LGL87_RS09310	COG4251	negative regulation of phosphorylation
LGL87_RS09310	COG5001	Diguanylate cyclase
LGL87_RS09390	COG1276	copper resistance
LGL87_RS09395	COG2372	response to copper ion
LGL87_RS09400	COG1528	Iron-storage protein
LGL87_RS09415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL87_RS09420	COG1770	oligopeptidase
LGL87_RS09430	COG3097	Belongs to the UPF0267 family
LGL87_RS09435	COG3141	response to X-ray
LGL87_RS09440	COG0513	Belongs to the DEAD box helicase family
LGL87_RS09460	COG0494	nUDIX hydrolase
LGL87_RS09465	COG1760	l-serine dehydratase
LGL87_RS09470	COG1253	flavin adenine dinucleotide binding
LGL87_RS09475	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL87_RS09475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL87_RS09480	COG3715	PTS system
LGL87_RS09485	COG3716	PTS system mannose fructose sorbose family IID component
LGL87_RS09490	COG4811	Protein of unknown function (DUF986)
LGL87_RS09495	COG1971	Probably functions as a manganese efflux pump
LGL87_RS09515	COG1960	acyl-CoA dehydrogenase activity
LGL87_RS09525	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL87_RS09555	COG2226	methyltransferase
LGL87_RS09560	COG0768	penicillin binding
LGL87_RS09565	COG1496	oxidoreductase activity
LGL87_RS09585	COG1113	amino acid transport
LGL87_RS09620	COG2207	Transcriptional regulator
LGL87_RS09640	COG1132	(ABC) transporter
LGL87_RS09650	COG3706	GGDEF domain
LGL87_RS09650	COG4251	negative regulation of phosphorylation
LGL87_RS09650	COG5001	Diguanylate cyclase
LGL87_RS09650	COG2203	Gaf domain
LGL87_RS09670	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL87_RS09690	COG1278	Cold shock
LGL87_RS09695	COG1278	Cold shock
LGL87_RS09710	COG1917	Cupin 2, conserved barrel domain protein
LGL87_RS09710	COG2169	Transcriptional regulator
LGL87_RS09715	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL87_RS09720	COG2723	6-phospho-beta-galactosidase activity
LGL87_RS09725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL87_RS09730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL87_RS09735	COG1187	pseudouridine synthase activity
LGL87_RS09745	COG3122	Protein conserved in bacteria
LGL87_RS09750	COG1757	Na H antiporter
LGL87_RS09765	COG2235	arginine
LGL87_RS09780	COG0076	glutamate decarboxylase activity
LGL87_RS09785	COG0531	amino acid
LGL87_RS09820	COG2153	protein acetylation
LGL87_RS09825	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL87_RS09855	COG0840	transmembrane signaling receptor activity
LGL87_RS09995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGL87_RS10020	COG3299	homolog of phage Mu protein gp47
LGL87_RS10070	COG4386	tail sheath protein
LGL87_RS10265	COG3179	chitinase
LGL87_RS10400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL87_RS10405	COG0322	excinuclease ABC activity
LGL87_RS10410	COG2197	response regulator
LGL87_RS10435	COG1113	amino acid transport
LGL87_RS10445	COG0531	amino acid
LGL87_RS10450	COG3710	Transcriptional regulator
LGL87_RS10455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL87_RS10460	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL87_RS10460	COG0506	proline dehydrogenase activity
LGL87_RS10460	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL87_RS10465	COG1126	abc transporter atp-binding protein
LGL87_RS10470	COG0765	amino acid transport
LGL87_RS10475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL87_RS10480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL87_RS10490	COG1191	sigma factor activity
LGL87_RS10525	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL87_RS10530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL87_RS10545	COG1677	Flagellar hook-basal body complex protein FliE
LGL87_RS10555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL87_RS10560	COG1317	bacterial-type flagellum organization
LGL87_RS10565	COG1157	protein secretion by the type III secretion system
LGL87_RS10580	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL87_RS10660	COG1558	bacterial-type flagellum-dependent cell motility
LGL87_RS10665	COG1815	bacterial-type flagellum-dependent cell motility
LGL87_RS10675	COG2747	anti-sigma28 factor FlgM
LGL87_RS10680	COG3418	PFAM FlgN family protein
LGL87_RS10690	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL87_RS10695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL87_RS10700	COG4935	Belongs to the peptidase S8 family
LGL87_RS10700	COG1404	Belongs to the peptidase S8 family
LGL87_RS10705	COG2197	response regulator
LGL87_RS10720	COG3188	usher protein
LGL87_RS10730	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL87_RS10735	COG0745	RESPONSE REGULATOR receiver
LGL87_RS10745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL87_RS10750	COG0840	transmembrane signaling receptor activity
LGL87_RS10755	COG0840	transmembrane signaling receptor activity
LGL87_RS10765	COG0835	chemotaxis
LGL87_RS10770	COG2198	Histidine kinase
LGL87_RS10770	COG0643	Histidine kinase
LGL87_RS10775	COG1360	Flagellar Motor Protein
LGL87_RS10795	COG0589	response to stress
LGL87_RS10800	COG1285	pathogenesis
LGL87_RS10805	COG0840	transmembrane signaling receptor activity
LGL87_RS10825	COG1609	Transcriptional regulator
LGL87_RS10835	COG0604	alcohol dehydrogenase
LGL87_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
LGL87_RS10835	COG3321	synthase
LGL87_RS10885	COG0471	metal ion transport
LGL87_RS10900	COG3051	citrate lyase alpha subunit
LGL87_RS10905	COG2301	Belongs to the HpcH HpaI aldolase family
LGL87_RS10910	COG3052	prosthetic group binding
LGL87_RS10915	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL87_RS10920	COG3290	protein histidine kinase activity
LGL87_RS10925	COG4565	transcriptional regulatory protein
LGL87_RS10940	COG2271	Major facilitator Superfamily
LGL87_RS10945	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL87_RS10955	COG3842	ATPase activity
LGL87_RS10970	COG0582	viral genome integration into host DNA
LGL87_RS10985	COG3423	Transcriptional regulator
LGL87_RS11020	COG3451	type IV secretory pathway VirB4
LGL87_RS11040	COG3736	Type IV secretory pathway, component VirB8
LGL87_RS11055	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LGL87_RS11070	COG4227	nucleotidyltransferase activity
LGL87_RS11120	COG1289	transmembrane transporter activity
LGL87_RS11130	COG2925	Exonuclease
LGL87_RS11135	COG0531	amino acid
LGL87_RS11140	COG4771	TonB-dependent receptor
LGL87_RS11150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL87_RS11160	COG0833	amino acid
LGL87_RS11165	COG0583	DNA-binding transcription factor activity
LGL87_RS11175	COG2855	membrane
LGL87_RS11180	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL87_RS11185	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL87_RS11185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL87_RS11185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL87_RS11190	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL87_RS11205	COG3005	denitrification pathway
LGL87_RS11210	COG0243	molybdopterin cofactor binding
LGL87_RS11230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL87_RS11240	COG0246	Mannitol dehydrogenase
LGL87_RS11250	COG0523	cobalamin synthesis protein
LGL87_RS11255	COG0671	phosphoesterase, PA-phosphatase related
LGL87_RS11260	COG0791	NLP P60 protein
LGL87_RS11265	COG2200	EAL domain
LGL87_RS11270	COG4166	transmembrane transport
LGL87_RS11275	COG4174	ABC transporter (Permease)
LGL87_RS11280	COG4239	(ABC) transporter, permease
LGL87_RS11285	COG4172	Belongs to the ABC transporter superfamily
LGL87_RS11295	COG2814	Major facilitator Superfamily
LGL87_RS11300	COG1187	pseudouridine synthase activity
LGL87_RS11305	COG1061	Type III restriction enzyme res subunit
LGL87_RS11320	COG3082	Protein of unknown function (DUF1414)
LGL87_RS11325	COG3083	sulfuric ester hydrolase activity
LGL87_RS11365	COG3299	homolog of phage Mu protein gp47
LGL87_RS11415	COG4386	tail sheath protein
LGL87_RS11455	COG0616	signal peptide processing
LGL87_RS11490	COG3646	Phage regulatory protein
LGL87_RS11500	COG0675	Transposase, IS605 OrfB family
LGL87_RS11535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL87_RS11540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL87_RS11560	COG2223	nitrite transmembrane transporter activity
LGL87_RS11565	COG2198	Histidine kinase
LGL87_RS11565	COG0642	Histidine kinase
LGL87_RS11575	COG2205	protein histidine kinase activity
LGL87_RS11575	COG0784	Response regulator, receiver
LGL87_RS11585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL87_RS11590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL87_RS11600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL87_RS11610	COG4574	serine-type endopeptidase inhibitor activity
LGL87_RS11620	COG2246	polysaccharide biosynthetic process
LGL87_RS11635	COG0814	amino acid
LGL87_RS11660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL87_RS11665	COG0596	Alpha beta hydrolase
LGL87_RS11670	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL87_RS11675	COG1169	isochorismate synthase
LGL87_RS11680	COG4575	ribosome binding
LGL87_RS11695	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL87_RS11700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL87_RS11710	COG0839	Belongs to the complex I subunit 6 family
LGL87_RS11715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL87_RS11720	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL87_RS11725	COG1034	ATP synthesis coupled electron transport
LGL87_RS11745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL87_RS11750	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL87_RS11755	COG0583	DNA-binding transcription factor activity
LGL87_RS11760	COG0436	Aminotransferase
LGL87_RS11765	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL87_RS11770	COG0490	domain, Protein
LGL87_RS11770	COG0471	metal ion transport
LGL87_RS11780	COG3013	Belongs to the UPF0304 family
LGL87_RS11785	COG3092	negative regulation of chromosome organization
LGL87_RS11795	COG0280	phosphate acetyltransferase
LGL87_RS11795	COG0857	belongs to the CobB CobQ family
LGL87_RS11800	COG1609	Transcriptional regulator
LGL87_RS11815	COG3037	sugar-specific permease SgaT UlaA
LGL87_RS11820	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL87_RS11825	COG0622	Phosphoesterase
LGL87_RS11835	COG0625	glutathione transferase activity
LGL87_RS11840	COG1090	epimerase
LGL87_RS11850	COG4160	amino acid transport
LGL87_RS11855	COG4215	(ABC) transporter
LGL87_RS11870	COG0163	prenyltransferase activity
LGL87_RS11875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL87_RS11880	COG1286	toxin biosynthetic process
LGL87_RS11885	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL87_RS11890	COG0285	dihydrofolate synthase activity
LGL87_RS11900	COG0586	Pfam SNARE associated Golgi protein
LGL87_RS11910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL87_RS11935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL87_RS11940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL87_RS11970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL87_RS11985	COG3101	peptidyl-lysine hydroxylation
LGL87_RS11990	COG0730	response to heat
LGL87_RS11995	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL87_RS12005	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL87_RS12010	COG2840	Smr protein MutS2
LGL87_RS12015	COG2062	phosphohistidine phosphatase, SixA
LGL87_RS12020	COG1024	Enoyl-CoA hydratase
LGL87_RS12020	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL87_RS12025	COG0183	Belongs to the thiolase family
LGL87_RS12030	COG3691	Protein conserved in bacteria
LGL87_RS12045	COG4235	cytochrome complex assembly
LGL87_RS12045	COG3088	subunit of a heme lyase
LGL87_RS12050	COG4235	cytochrome complex assembly
LGL87_RS12050	COG3088	subunit of a heme lyase
LGL87_RS12055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL87_RS12060	COG1138	Cytochrome C-type biogenesis protein
LGL87_RS12065	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL87_RS12070	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL87_RS12075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL87_RS12080	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL87_RS12100	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL87_RS12105	COG2951	lytic endotransglycosylase activity
LGL87_RS12110	COG1598	PFAM Uncharacterised protein family UPF0150
LGL87_RS12120	COG3038	cytochrome b561
LGL87_RS12125	COG0436	Aminotransferase
LGL87_RS12135	COG3275	phosphorelay sensor kinase activity
LGL87_RS12140	COG3279	Response regulator of the LytR AlgR family
LGL87_RS12145	COG2223	nitrite transmembrane transporter activity
LGL87_RS12150	COG0837	glucose binding
LGL87_RS12170	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL87_RS12175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL87_RS12235	COG3530	Putative quorum-sensing-regulated virulence factor
LGL87_RS12240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL87_RS12250	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL87_RS12260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL87_RS12275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL87_RS12285	COG4208	sulfate ABC transporter
LGL87_RS12290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL87_RS12295	COG4150	thiosulfate binding
LGL87_RS12305	COG1737	Transcriptional regulator
LGL87_RS12310	COG2731	YhcH YjgK YiaL family protein
LGL87_RS12325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL87_RS12330	COG2837	iron assimilation
LGL87_RS12340	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL87_RS12445	COG1671	Belongs to the UPF0178 family
LGL87_RS12450	COG0280	phosphate acetyltransferase
LGL87_RS12450	COG0281	malic enzyme
LGL87_RS12455	COG0494	nUDIX hydrolase
LGL87_RS12460	COG3005	denitrification pathway
LGL87_RS12465	COG3043	anaerobic respiration
LGL87_RS12470	COG0243	molybdopterin cofactor binding
LGL87_RS12475	COG3062	negative regulation of establishment of protein localization
LGL87_RS12480	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL87_RS12480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL87_RS12485	COG2197	response regulator
LGL87_RS12495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL87_RS12505	COG1605	Chorismate mutase
LGL87_RS12510	COG1393	Belongs to the ArsC family
LGL87_RS12515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL87_RS12520	COG1876	peptidase activity
LGL87_RS12530	COG0400	carboxylic ester hydrolase activity
LGL87_RS12550	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL87_RS12555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL87_RS12560	COG2716	regulation of RNA biosynthetic process
LGL87_RS12565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL87_RS12570	COG0628	permease
LGL87_RS12575	COG4783	chaperone-mediated protein folding
LGL87_RS12580	COG1393	Belongs to the ArsC family
LGL87_RS12585	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL87_RS12590	COG2233	PERMEase
LGL87_RS12595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL87_RS12600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL87_RS12605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL87_RS12610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL87_RS12620	COG0581	inorganic phosphate transmembrane transporter activity
LGL87_RS12625	COG0573	inorganic phosphate transmembrane transporter activity
LGL87_RS12630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL87_RS12645	COG2239	Acts as a magnesium transporter
LGL87_RS12650	COG0443	Heat shock 70 kDa protein
LGL87_RS12660	COG3121	Chaperone
LGL87_RS12675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL87_RS12685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL87_RS12690	COG0477	Major facilitator Superfamily
LGL87_RS12695	COG2205	protein histidine kinase activity
LGL87_RS12700	COG0745	RESPONSE REGULATOR receiver
LGL87_RS12705	COG3422	double-strand break repair
LGL87_RS12710	COG0826	peptidase U32
LGL87_RS12715	COG1597	lipid kinase activity
LGL87_RS12730	COG0351	phosphomethylpyrimidine kinase
LGL87_RS12740	COG0519	Catalyzes the synthesis of GMP from XMP
LGL87_RS12740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL87_RS12745	COG0517	IMP dehydrogenase activity
LGL87_RS12745	COG0516	GMP reductase activity
LGL87_RS12750	COG1570	exodeoxyribonuclease VII activity
LGL87_RS12755	COG1645	bacterial-type flagellum-dependent swarming motility
LGL87_RS12765	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL87_RS12770	COG2976	Protein conserved in bacteria
LGL87_RS12775	COG0124	histidyl-tRNA synthetase
LGL87_RS12795	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL87_RS12810	COG4953	penicillin-binding protein 1C
LGL87_RS12815	COG2373	Large extracellular alpha-helical protein
LGL87_RS12830	COG2975	iron-sulfur cluster assembly
LGL87_RS12835	COG0633	Ferredoxin
LGL87_RS12840	COG0443	Heat shock 70 kDa protein
LGL87_RS12855	COG0822	iron-sulfur transferase activity
LGL87_RS12865	COG1959	2 iron, 2 sulfur cluster binding
LGL87_RS12870	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL87_RS12880	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL87_RS12885	COG3683	transport system, periplasmic component
LGL87_RS12890	COG3711	transcriptional antiterminator
LGL87_RS12895	COG2814	Major facilitator Superfamily
LGL87_RS12905	COG1017	nitric oxide dioxygenase activity
LGL87_RS12905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL87_RS12910	COG2188	Transcriptional regulator
LGL87_RS12920	COG3457	Alanine racemase
LGL87_RS12925	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL87_RS12940	COG0347	Belongs to the P(II) protein family
LGL87_RS12945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL87_RS12945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL87_RS12950	COG2204	response regulator
LGL87_RS12955	COG3170	Tfp pilus assembly protein FimV
LGL87_RS12960	COG2205	protein histidine kinase activity
LGL87_RS12975	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL87_RS12985	COG0560	Phosphoserine phosphatase
LGL87_RS12990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL87_RS12990	COG1263	PTS System
LGL87_RS13000	COG1737	Transcriptional regulator
LGL87_RS13005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL87_RS13015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL87_RS13025	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL87_RS13040	COG0481	GTPase activity
LGL87_RS13045	COG3086	response to oxidative stress
LGL87_RS13055	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL87_RS13065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL87_RS13075	COG0513	Belongs to the DEAD box helicase family
LGL87_RS13090	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL87_RS13100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL87_RS13105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL87_RS13110	COG0497	DNA recombination
LGL87_RS13115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL87_RS13125	COG2867	negative regulation of translational initiation
LGL87_RS13130	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL87_RS13160	COG2963	transposase activity
LGL87_RS13170	COG1069	ribulokinase activity
LGL87_RS13180	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL87_RS13185	COG1129	ABC transporter
LGL87_RS13205	COG1620	l-lactate permease
LGL87_RS13210	COG1304	FMN binding
LGL87_RS13215	COG0579	oxidoreductase
LGL87_RS13220	COG1278	Cold shock
LGL87_RS13250	COG1780	Probably involved in ribonucleotide reductase function
LGL87_RS13255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL87_RS13265	COG4175	Glycine betaine
LGL87_RS13270	COG4176	ABC-type proline glycine betaine transport system permease component
LGL87_RS13275	COG2113	Glycine betaine
LGL87_RS13290	COG1846	Transcriptional regulator
LGL87_RS13300	COG1566	PFAM secretion protein HlyD family protein
LGL87_RS13305	COG2814	Major facilitator Superfamily
LGL87_RS13310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL87_RS13315	COG3118	belongs to the thioredoxin family
LGL87_RS13320	COG3148	PFAM DTW domain containing protein
LGL87_RS13325	COG1042	CoA-binding domain protein
LGL87_RS13325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL87_RS13325	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL87_RS13330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL87_RS13335	COG5544	Lipoprotein
LGL87_RS13360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL87_RS13370	COG2011	ABC-type metal ion transport system permease component
LGL87_RS13375	COG1464	Belongs to the NlpA lipoprotein family
LGL87_RS13385	COG1720	tRNA m6t6A37 methyltransferase activity
LGL87_RS13390	COG0442	prolyl-tRNA aminoacylation
LGL87_RS13395	COG3015	lipoprotein NlpE involved in copper resistance
LGL87_RS13405	COG4681	YaeQ
LGL87_RS13415	COG4568	rho-dependent transcription termination
LGL87_RS13430	COG0346	lactoylglutathione lyase activity
LGL87_RS13445	COG0825	malonyl-CoA metabolic process
LGL87_RS13450	COG0587	DNA-directed DNA polymerase activity
LGL87_RS13455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL87_RS13475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL87_RS13480	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL87_RS13490	COG0750	zinc metalloprotease
LGL87_RS13495	COG0575	Belongs to the CDS family
LGL87_RS13515	COG0528	UMP kinase activity
LGL87_RS13520	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL87_RS13540	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL87_RS13545	COG2171	N-acyltransferase activity
LGL87_RS13560	COG0564	pseudouridine synthase activity
LGL87_RS13565	COG3098	single-species biofilm formation
LGL87_RS13580	COG1611	Belongs to the LOG family
LGL87_RS13590	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL87_RS13595	COG2363	Small membrane protein
LGL87_RS13600	COG0583	DNA-binding transcription factor activity
LGL87_RS13610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL87_RS13615	COG2166	iron-sulfur cluster assembly
LGL87_RS13620	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL87_RS13625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL87_RS13645	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL87_RS13650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL87_RS13650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL87_RS13655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL87_RS13660	COG1074	ATP-dependent DNA helicase activity
LGL87_RS13665	COG1025	Belongs to the peptidase M16 family
LGL87_RS13670	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL87_RS13675	COG4967	type IV pilus modification protein PilV
LGL87_RS13700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL87_RS13705	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL87_RS13715	COG3066	DNA modification
LGL87_RS13720	COG0861	Integral membrane protein TerC family
LGL87_RS13725	COG0667	Aldo Keto reductase
LGL87_RS13730	COG0477	Major facilitator Superfamily
LGL87_RS13735	COG0204	Acyl-transferase
LGL87_RS13735	COG0318	PFAM AMP-dependent synthetase and ligase
LGL87_RS13745	COG1609	Transcriptional regulator
LGL87_RS13755	COG0583	DNA-binding transcription factor activity
LGL87_RS13760	COG0583	DNA-binding transcription factor activity
LGL87_RS13805	COG4795	General secretion pathway protein
LGL87_RS13820	COG2165	general secretion pathway protein
LGL87_RS13835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL87_RS13865	COG1127	ABC transporter
LGL87_RS13870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL87_RS13915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL87_RS13925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL87_RS13930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL87_RS13935	COG4974	Belongs to the 'phage' integrase family
LGL87_RS13940	COG0716	FMN binding
LGL87_RS13950	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL87_RS13960	COG1272	protein, Hemolysin III
LGL87_RS13980	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL87_RS13985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL87_RS13990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL87_RS13995	COG0006	proline dipeptidase activity
LGL87_RS14005	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL87_RS14015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL87_RS14020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL87_RS14025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL87_RS14040	COG1279	arginine transmembrane transporter activity
LGL87_RS14050	COG0191	fructose-bisphosphate aldolase activity
LGL87_RS14055	COG0126	phosphoglycerate kinase activity
LGL87_RS14060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL87_RS14065	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL87_RS14075	COG1166	arginine decarboxylase activity
LGL87_RS14080	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL87_RS14095	COG0640	Transcriptional regulator
LGL87_RS14100	COG3091	SprT-like family
LGL87_RS14105	COG2356	endonuclease I
LGL87_RS14110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL87_RS14115	COG0189	ligase activity
LGL87_RS14120	COG1678	Uncharacterized ACR, COG1678
LGL87_RS14125	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL87_RS14130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL87_RS14140	COG2805	Type II/IV secretion system protein
LGL87_RS14145	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL87_RS14150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL87_RS14155	COG0762	integral membrane protein
LGL87_RS14160	COG1872	DUF167
LGL87_RS14165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL87_RS14170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL87_RS14185	COG3171	Protein conserved in bacteria
LGL87_RS14195	COG1194	a g-specific adenine glycosylase
LGL87_RS14200	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL87_RS14205	COG0741	lytic transglycosylase activity
LGL87_RS14215	COG0582	viral genome integration into host DNA
LGL87_RS14240	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LGL87_RS14295	COG3596	GTP binding
LGL87_RS14380	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL87_RS14385	COG1882	Formate acetyltransferase
LGL87_RS14390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL87_RS14395	COG0814	amino acid
LGL87_RS14410	COG1028	Short-chain dehydrogenase reductase Sdr
LGL87_RS14415	COG3433	isochorismatase activity
LGL87_RS14415	COG1535	isochorismatase
LGL87_RS14420	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL87_RS14425	COG1169	isochorismate synthase
LGL87_RS14430	COG4592	Periplasmic binding protein
LGL87_RS14440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL87_RS14445	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL87_RS14450	COG1120	ATPase activity
LGL87_RS14460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL87_RS14465	COG3251	PFAM MbtH domain protein
LGL87_RS14475	COG4774	siderophore transport
LGL87_RS14480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL87_RS14500	COG4964	Belongs to the GSP D family
LGL87_RS14550	COG0848	biopolymer transport protein
LGL87_RS14555	COG0811	peptide transport
LGL87_RS14560	COG0626	cystathionine gamma-synthase activity
LGL87_RS14565	COG0586	Pfam SNARE associated Golgi protein
LGL87_RS14570	COG2207	Transcriptional regulator
LGL87_RS14575	COG1979	alcohol dehydrogenase
LGL87_RS14580	COG0656	L-ascorbic acid biosynthetic process
LGL87_RS14590	COG2132	Multicopper oxidase
LGL87_RS14600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGL87_RS14605	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL87_RS14610	COG0583	DNA-binding transcription factor activity
LGL87_RS14615	COG0187	DNA topoisomerase II activity
LGL87_RS14620	COG3150	esterase
LGL87_RS14625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL87_RS14630	COG3151	Protein conserved in bacteria
LGL87_RS14635	COG0494	nUDIX hydrolase
LGL87_RS14640	COG1538	Outer membrane efflux protein
LGL87_RS14645	COG5463	Belongs to the UPF0441 family
LGL87_RS14650	COG0754	glutathionylspermidine amidase activity
LGL87_RS14655	COG3384	dioxygenase
LGL87_RS14660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL87_RS14670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL87_RS14670	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL87_RS14680	COG3025	triphosphatase activity
LGL87_RS14685	COG4991	sh3 domain protein
LGL87_RS14690	COG0617	tRNA 3'-terminal CCA addition
LGL87_RS14695	COG1968	undecaprenyl-diphosphatase activity
LGL87_RS14700	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL87_RS14705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL87_RS14710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL87_RS14715	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL87_RS14720	COG0358	DNA primase activity
LGL87_RS14750	COG1028	Short-chain dehydrogenase reductase Sdr
LGL87_RS14780	COG0463	Glycosyl transferase, family 2
LGL87_RS14845	COG3210	domain, Protein
LGL87_RS14850	COG2831	hemolysin activation secretion protein
LGL87_RS14855	COG1902	pentaerythritol trinitrate reductase activity
LGL87_RS14855	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL87_RS14870	COG1451	nucleotide metabolic process
LGL87_RS14875	COG0673	inositol 2-dehydrogenase activity
LGL87_RS14880	COG0861	Integral membrane protein TerC family
LGL87_RS14885	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL87_RS14895	COG2721	sulfolactate sulfo-lyase activity
LGL87_RS14910	COG2271	Major facilitator Superfamily
LGL87_RS14925	COG0586	Pfam SNARE associated Golgi protein
LGL87_RS14940	COG4575	ribosome binding
LGL87_RS14945	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL87_RS14955	COG2259	Doxx family
LGL87_RS14960	COG0583	DNA-binding transcription factor activity
LGL87_RS14965	COG1741	Belongs to the pirin family
LGL87_RS14980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL87_RS14995	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL87_RS15000	COG2823	Periplasmic or secreted lipoprotein
LGL87_RS15005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL87_RS15010	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL87_RS15015	COG5002	protein histidine kinase activity
LGL87_RS15015	COG2198	Histidine kinase
LGL87_RS15015	COG0784	Response regulator, receiver
LGL87_RS15025	COG1242	4 iron, 4 sulfur cluster binding
LGL87_RS15030	COG0070	glutamate synthase
LGL87_RS15030	COG0069	glutamate synthase activity
LGL87_RS15030	COG0067	glutamate synthase
LGL87_RS15035	COG0493	'glutamate synthase
LGL87_RS15045	COG2969	positive regulation of protein catabolic process
LGL87_RS15050	COG0625	glutathione transferase activity
LGL87_RS15055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL87_RS15060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL87_RS15065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL87_RS15070	COG3105	Protein conserved in bacteria
LGL87_RS15075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL87_RS15085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL87_RS15090	COG5007	Belongs to the BolA IbaG family
LGL87_RS15095	COG3113	response to antibiotic
LGL87_RS15100	COG2854	intermembrane phospholipid transfer
LGL87_RS15105	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL87_RS15110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL87_RS15115	COG1127	ABC transporter
LGL87_RS15120	COG0530	calcium, potassium:sodium antiporter activity
LGL87_RS15125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL87_RS15125	COG0517	IMP dehydrogenase activity
LGL87_RS15130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL87_RS15135	COG3117	lipopolysaccharide transmembrane transporter activity
LGL87_RS15140	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL87_RS15145	COG1137	ATPase activity
LGL87_RS15150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL87_RS15170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL87_RS15175	COG0540	Belongs to the ATCase OTCase family
LGL87_RS15180	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL87_RS15190	COG0366	Alpha amylase catalytic
LGL87_RS15195	COG1263	PTS System
LGL87_RS15195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL87_RS15205	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL87_RS15215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL87_RS15220	COG3783	Cytochrome b(562)
LGL87_RS15225	COG0312	modulator of DNA gyrase
LGL87_RS15230	COG3028	Belongs to the UPF0307 family
LGL87_RS15235	COG2732	(Barnase) inhibitor
LGL87_RS15240	COG4290	ribonuclease
LGL87_RS15250	COG1289	transmembrane transporter activity
LGL87_RS15255	COG1566	PFAM secretion protein HlyD family protein
LGL87_RS15265	COG0583	DNA-binding transcription factor activity
LGL87_RS15270	COG0312	modulator of DNA gyrase
LGL87_RS15275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL87_RS15280	COG3164	Protein of unknown function
LGL87_RS15290	COG0424	maF-like protein
LGL87_RS15295	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL87_RS15300	COG1792	Involved in formation and maintenance of cell shape
LGL87_RS15305	COG1077	Cell shape determining protein MreB Mrl
LGL87_RS15310	COG2200	EAL domain
LGL87_RS15310	COG2199	diguanylate cyclase activity
LGL87_RS15315	COG0604	alcohol dehydrogenase
LGL87_RS15320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL87_RS15325	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL87_RS15335	COG0511	ligase activity, forming carbon-carbon bonds
LGL87_RS15340	COG0439	Biotin carboxylase
LGL87_RS15345	COG3924	membrane
LGL87_RS15350	COG4145	pantothenate transmembrane transporter activity
LGL87_RS15355	COG2264	protein methyltransferase activity
LGL87_RS15360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL87_RS15365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL87_RS15375	COG1560	Kdo2-lipid A biosynthetic process
LGL87_RS15385	COG1346	cytolysis
LGL87_RS15390	COG1380	Effector of murein hydrolase LrgA
LGL87_RS15395	COG0583	DNA-binding transcription factor activity
LGL87_RS15400	COG0025	NhaP-type Na H and K H
LGL87_RS15405	COG2252	PERMEase
LGL87_RS15420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL87_RS15425	COG2315	Protein conserved in bacteria
LGL87_RS15430	COG1448	Aminotransferase
LGL87_RS15445	COG0604	alcohol dehydrogenase
LGL87_RS15455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL87_RS15460	COG0735	belongs to the Fur family
LGL87_RS15465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL87_RS15470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL87_RS15475	COG2937	Belongs to the GPAT DAPAT family
LGL87_RS15495	COG4580	involved in the transport of maltose and maltodextrins
LGL87_RS15510	COG2182	Extracellular solute-binding protein
LGL87_RS15515	COG1175	transmembrane transport
LGL87_RS15520	COG3833	ABC-type maltose transport systems, permease component
LGL87_RS15525	COG3223	Belongs to the PsiE family
LGL87_RS15535	COG0527	aspartate kinase activity
LGL87_RS15550	COG3328	transposase activity
LGL87_RS15585	COG1222	aaa ATPase
LGL87_RS15665	COG0583	DNA-binding transcription factor activity
LGL87_RS15700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL87_RS15740	COG0138	bifunctional purine biosynthesis protein purh
LGL87_RS15745	COG0151	Belongs to the GarS family
LGL87_RS15765	COG1515	deoxyribonuclease V activity
LGL87_RS15770	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL87_RS15775	COG2816	NAD+ diphosphatase activity
LGL87_RS15780	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL87_RS15795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL87_RS15800	COG2104	thiamine diphosphate biosynthetic process
LGL87_RS15805	COG2022	thiamine diphosphate biosynthetic process
LGL87_RS15815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL87_RS15820	COG0085	RNA polymerase activity
LGL87_RS15825	COG0222	ribosome binding
LGL87_RS15830	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL87_RS15840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL87_RS15845	COG0250	Participates in transcription elongation, termination and antitermination
LGL87_RS15890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL87_RS15915	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL87_RS15920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL87_RS15925	COG1739	Uncharacterized protein family UPF0029
LGL87_RS15935	COG1024	Enoyl-CoA hydratase
LGL87_RS15935	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL87_RS15945	COG0543	2 iron, 2 sulfur cluster binding
LGL87_RS15960	COG0250	Participates in transcription elongation, termination and antitermination
LGL87_RS15975	COG0805	protein transport
LGL87_RS15980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL87_RS15985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL87_RS15990	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL87_RS15995	COG3165	ubiquinone biosynthetic process from chorismate
LGL87_RS16000	COG2226	methyltransferase
LGL87_RS16005	COG1322	Protein conserved in bacteria
LGL87_RS16010	COG0586	Pfam SNARE associated Golgi protein
LGL87_RS16015	COG1966	Carbon starvation protein
LGL87_RS16030	COG0412	Dienelactone hydrolase
LGL87_RS16035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL87_RS16040	COG0583	DNA-binding transcription factor activity
LGL87_RS16045	COG0697	spore germination
LGL87_RS16055	COG0584	glycerophosphoryl diester phosphodiesterase
LGL87_RS16065	COG0395	ABC-type sugar transport system, permease component
LGL87_RS16070	COG1175	transmembrane transport
LGL87_RS16075	COG1653	transport
LGL87_RS16110	COG0410	ABC transporter
LGL87_RS16120	COG4177	L-phenylalanine transmembrane transporter activity
LGL87_RS16140	COG1929	Belongs to the glycerate kinase type-1 family
LGL87_RS16145	COG2610	gluconate transmembrane transporter activity
LGL87_RS16150	COG3835	regulator
LGL87_RS16160	COG2177	Part of the ABC transporter FtsEX involved in
LGL87_RS16165	COG2884	Cell division ATP-binding protein ftsE
LGL87_RS16170	COG0552	protein localization to endoplasmic reticulum
LGL87_RS16170	COG0552	protein localization to endoplasmic reticulum
LGL87_RS16175	COG0742	ribosomal rna small subunit methyltransferase
LGL87_RS16180	COG3776	membrane
LGL87_RS16195	COG3714	YhhN family
LGL87_RS16210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL87_RS16220	COG0247	lactate metabolic process
LGL87_RS16230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL87_RS16240	COG2271	Major facilitator Superfamily
LGL87_RS16245	COG0584	glycerophosphoryl diester phosphodiesterase
LGL87_RS16250	COG0561	phosphatase activity
LGL87_RS16255	COG2267	carboxylic ester hydrolase activity
LGL87_RS16260	COG1280	lysine exporter protein (LysE YggA)
LGL87_RS16265	COG0514	ATP-dependent DNA helicase (RecQ)
LGL87_RS16270	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL87_RS16275	COG2050	protein possibly involved in aromatic compounds catabolism
LGL87_RS16295	COG5564	TIM-barrel signal transduction protein
LGL87_RS16300	COG5441	Belongs to the UPF0261 family
LGL87_RS16310	COG0210	DNA helicase
LGL87_RS16315	COG1011	Hydrolase
LGL87_RS16320	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL87_RS16325	COG3159	Protein conserved in bacteria
LGL87_RS16330	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL87_RS16335	COG5567	small periplasmic lipoprotein
LGL87_RS16345	COG3072	Adenylate cyclase
LGL87_RS16350	COG0181	hydroxymethylbilane synthase activity
LGL87_RS16355	COG1587	Uroporphyrinogen-III synthase
LGL87_RS16360	COG2959	enzyme of heme biosynthesis
LGL87_RS16365	COG3071	HemY protein
LGL87_RS16415	COG2244	polysaccharide biosynthetic process
LGL87_RS16420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL87_RS16425	COG0456	acetyltransferase
LGL87_RS16430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL87_RS16435	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL87_RS16440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL87_RS16445	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL87_RS16450	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL87_RS16455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL87_RS16460	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL87_RS16465	COG3118	belongs to the thioredoxin family
LGL87_RS16475	COG0248	Ppx GppA phosphatase
LGL87_RS16485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL87_RS16500	COG3397	chitin binding
LGL87_RS16510	COG0129	dihydroxy-acid dehydratase activity
LGL87_RS16520	COG3978	acetolactate synthase activity
LGL87_RS16540	COG3085	chromosome segregation
LGL87_RS16545	COG0583	DNA-binding transcription factor activity
LGL87_RS16625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL87_RS16635	COG0678	peroxiredoxin activity
LGL87_RS16635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL87_RS16640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL87_RS16675	COG1629	transport
LGL87_RS16680	COG0165	Argininosuccinate lyase
LGL87_RS16685	COG0137	argininosuccinate synthase activity
LGL87_RS16690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL87_RS16740	COG0527	aspartate kinase activity
LGL87_RS16740	COG0460	homoserine dehydrogenase
LGL87_RS16745	COG0626	cystathionine gamma-synthase activity
LGL87_RS16750	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL87_RS16760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL87_RS16765	COG1609	Transcriptional regulator
LGL87_RS16770	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL87_RS16775	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL87_RS16780	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL87_RS16785	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL87_RS16790	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL87_RS16795	COG3074	FtsZ-dependent cytokinesis
LGL87_RS16800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL87_RS16805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL87_RS16810	COG1494	fructose-1,6-bisphosphatase
LGL87_RS16815	COG2814	Major facilitator Superfamily
LGL87_RS16825	COG3152	Membrane
LGL87_RS16840	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL87_RS16850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL87_RS16855	COG3678	ATP-independent chaperone mediated protein folding
LGL87_RS16860	COG0745	RESPONSE REGULATOR receiver
LGL87_RS16865	COG2205	protein histidine kinase activity
LGL87_RS16870	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL87_RS16875	COG1045	serine acetyltransferase
LGL87_RS16880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL87_RS16885	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL87_RS16890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL87_RS16895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL87_RS16900	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL87_RS16905	COG4942	peptidase
LGL87_RS16910	COG2861	carbohydrate metabolic process
LGL87_RS16925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL87_RS16930	COG0859	PFAM glycosyl transferase family 9
LGL87_RS16935	COG0859	PFAM glycosyl transferase family 9
LGL87_RS16940	COG1519	Transferase
LGL87_RS16960	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL87_RS16965	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL87_RS16970	COG2003	Belongs to the UPF0758 family
LGL87_RS16975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL87_RS16980	COG0756	dUTP diphosphatase activity
LGL87_RS16985	COG1309	transcriptional regulator
LGL87_RS16990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL87_RS16995	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL87_RS17000	COG1561	YicC-like family, N-terminal region
LGL87_RS17015	COG5001	Diguanylate cyclase
LGL87_RS17020	COG1024	Enoyl-CoA hydratase
LGL87_RS17025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL87_RS17040	COG2860	membrane
LGL87_RS17045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL87_RS17055	COG1758	RNA polymerase activity
LGL87_RS17060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL87_RS17065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL87_RS17070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL87_RS17075	COG0786	glutamate:sodium symporter activity
LGL87_RS17080	COG2233	PERMEase
LGL87_RS17085	COG2982	Protein involved in outer membrane biogenesis
LGL87_RS17090	COG0456	acetyltransferase
LGL87_RS17105	COG1011	Hydrolase
LGL87_RS17120	COG3852	Histidine kinase
LGL87_RS17130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL87_RS17140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL87_RS17145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL87_RS17145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL87_RS17150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL87_RS17155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL87_RS17160	COG3084	Protein conserved in bacteria
LGL87_RS17170	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL87_RS17195	COG2186	Transcriptional regulator
LGL87_RS17200	COG1609	Transcriptional regulator
LGL87_RS17205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL87_RS17215	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL87_RS17220	COG1129	ABC transporter
LGL87_RS17225	COG1869	D-ribose catabolic process
LGL87_RS17230	COG3158	transport of potassium into the cell
LGL87_RS17235	COG0714	Associated with various cellular activities
LGL87_RS17240	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL87_RS17250	COG2502	aspartate--ammonia ligase
LGL87_RS17255	COG1522	sequence-specific DNA binding
LGL87_RS17260	COG0716	FMN binding
LGL87_RS17265	COG0445	tRNA wobble uridine modification
LGL87_RS17270	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL87_RS17275	COG3312	ion transport
LGL87_RS17280	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL87_RS17290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL87_RS17300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL87_RS17305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL87_RS17315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL87_RS17330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL87_RS17335	COG0573	inorganic phosphate transmembrane transporter activity
LGL87_RS17340	COG0581	inorganic phosphate transmembrane transporter activity
LGL87_RS17350	COG0704	Plays a role in the regulation of phosphate uptake
LGL87_RS17355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL87_RS17360	COG0765	amino acid transport
LGL87_RS17365	COG0765	amino acid transport
LGL87_RS17370	COG2252	PERMEase
LGL87_RS17375	COG0840	transmembrane signaling receptor activity
LGL87_RS17385	COG3121	Chaperone
LGL87_RS17400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL87_RS17405	COG0706	membrane insertase activity
LGL87_RS17415	COG0594	ribonuclease P activity
LGL87_RS17420	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGL87_RS17505	COG1196	nuclear chromosome segregation
LGL87_RS17625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL87_RS17640	COG0741	lytic transglycosylase activity
LGL87_RS17805	COG2944	sequence-specific DNA binding
