locus-tag	class	description
LGL89_RS00010	COG0592	DNA-directed DNA polymerase activity
LGL89_RS00020	COG0187	DNA topoisomerase II activity
LGL89_RS00025	COG0561	phosphatase activity
LGL89_RS00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL89_RS00035	COG5645	(Lipo)protein
LGL89_RS00050	COG0569	domain protein
LGL89_RS00050	COG2985	domain, Protein
LGL89_RS00055	COG3977	Valine--pyruvate aminotransferase
LGL89_RS00060	COG2885	chlorophyll binding
LGL89_RS00080	COG2818	Glycosylase
LGL89_RS00130	COG2213	PTS system mannitol-specific
LGL89_RS00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL89_RS00140	COG3722	fumarate hydratase activity
LGL89_RS00150	COG2258	MOSC domain
LGL89_RS00155	COG0840	transmembrane signaling receptor activity
LGL89_RS00160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL89_RS00175	COG0437	4 iron, 4 sulfur cluster binding
LGL89_RS00180	COG2864	formate dehydrogenase
LGL89_RS00190	COG1921	L-seryl-tRNASec selenium transferase activity
LGL89_RS00195	COG3276	selenocysteine insertion sequence binding
LGL89_RS00200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL89_RS00210	COG3274	enterobacterial common antigen metabolic process
LGL89_RS00245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL89_RS00250	COG2986	histidine ammonia-lyase
LGL89_RS00270	COG2194	sulfuric ester hydrolase activity
LGL89_RS00275	COG2197	response regulator
LGL89_RS00280	COG3851	Histidine kinase
LGL89_RS00285	COG2271	Major facilitator Superfamily
LGL89_RS00295	COG0747	negative chemotaxis
LGL89_RS00300	COG0601	transmembrane transport
LGL89_RS00305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL89_RS00310	COG0444	Belongs to the ABC transporter superfamily
LGL89_RS00315	COG4608	Belongs to the ABC transporter superfamily
LGL89_RS00320	COG2194	sulfuric ester hydrolase activity
LGL89_RS00345	COG1215	transferase activity, transferring glycosyl groups
LGL89_RS00350	COG1215	transferase activity, transferring glycosyl groups
LGL89_RS00355	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL89_RS00360	COG3118	belongs to the thioredoxin family
LGL89_RS00360	COG0457	Tetratricopeptide repeat
LGL89_RS00365	COG2199	diguanylate cyclase activity
LGL89_RS00365	COG2200	EAL domain
LGL89_RS00370	COG1301	dicarboxylic acid transport
LGL89_RS00375	COG0612	Peptidase, M16
LGL89_RS00380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL89_RS00385	COG1942	4-Oxalocrotonate Tautomerase
LGL89_RS00390	COG2200	EAL domain
LGL89_RS00395	COG2134	cdp-diacylglycerol pyrophosphatase
LGL89_RS00400	COG1295	ribonuclease BN
LGL89_RS00410	COG1301	dicarboxylic acid transport
LGL89_RS00415	COG0626	cystathionine gamma-synthase activity
LGL89_RS00420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL89_RS00425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL89_RS00430	COG0339	signal peptide processing
LGL89_RS00435	COG0742	ribosomal rna small subunit methyltransferase
LGL89_RS00445	COG0589	response to stress
LGL89_RS00455	COG0306	phosphate transporter
LGL89_RS00460	COG2081	HI0933 family
LGL89_RS00470	COG1247	-acetyltransferase
LGL89_RS00480	COG1741	Belongs to the pirin family
LGL89_RS00485	COG1609	Transcriptional regulator
LGL89_RS00495	COG3265	gluconokinase activity
LGL89_RS00500	COG2095	MarC family integral membrane protein
LGL89_RS00505	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL89_RS00510	COG3275	phosphorelay sensor kinase activity
LGL89_RS00515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL89_RS00520	COG1523	belongs to the glycosyl hydrolase 13 family
LGL89_RS00525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL89_RS00530	COG0297	glycogen (starch) synthase activity
LGL89_RS00535	COG0058	SHG alpha-glucan phosphorylase activity
LGL89_RS00540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL89_RS00545	COG1349	DNA-binding transcription factor activity
LGL89_RS00550	COG0705	Rhomboid family
LGL89_RS00560	COG2909	trisaccharide binding
LGL89_RS00565	COG0058	SHG alpha-glucan phosphorylase activity
LGL89_RS00570	COG1640	4-alpha-glucanotransferase
LGL89_RS00580	COG1040	competence protein
LGL89_RS00585	COG0596	Alpha beta hydrolase
LGL89_RS00605	COG1918	ferrous iron import across plasma membrane
LGL89_RS00610	COG2183	response to ionizing radiation
LGL89_RS00635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL89_RS00650	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL89_RS00660	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL89_RS00665	COG1011	Hydrolase
LGL89_RS00675	COG0494	nUDIX hydrolase
LGL89_RS00680	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL89_RS00705	COG4796	Type ii and iii secretion system protein
LGL89_RS00710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL89_RS00730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL89_RS00740	COG0180	Tryptophanyl-tRNA synthetase
LGL89_RS00760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL89_RS00765	COG0402	S-adenosylhomocysteine deaminase activity
LGL89_RS00770	COG0738	Major facilitator superfamily
LGL89_RS00785	COG1609	Transcriptional regulator
LGL89_RS00790	COG1486	melibiose metabolic process
LGL89_RS00795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL89_RS00810	COG1289	transmembrane transporter activity
LGL89_RS00815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL89_RS00820	COG1765	OsmC-like protein
LGL89_RS00845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL89_RS00850	COG3954	Phosphoribulokinase
LGL89_RS00860	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL89_RS00870	COG0859	PFAM glycosyl transferase family 9
LGL89_RS00875	COG1216	Glycosyl transferase, family 2
LGL89_RS00880	COG0488	(ABC) transporter
LGL89_RS00885	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL89_RS00895	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL89_RS00900	COG1047	Peptidyl-prolyl cis-trans
LGL89_RS00910	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL89_RS00915	COG2964	Protein conserved in bacteria
LGL89_RS00925	COG2923	Belongs to the DsrF TusC family
LGL89_RS00930	COG2168	tRNA wobble position uridine thiolation
LGL89_RS00935	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL89_RS00940	COG0049	tRNA binding
LGL89_RS00950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL89_RS00965	COG0051	transcription antitermination factor activity, RNA binding
LGL89_RS00970	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL89_RS00980	COG0089	rRNA binding
LGL89_RS00985	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL89_RS00990	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL89_RS00995	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL89_RS01005	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL89_RS01010	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL89_RS01015	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL89_RS01020	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL89_RS01030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL89_RS01055	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL89_RS01060	COG1841	ribosomal large subunit assembly
LGL89_RS01065	COG0200	Binds to the 23S rRNA
LGL89_RS01070	COG0201	protein transport
LGL89_RS01075	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL89_RS01080	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL89_RS01090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL89_RS01100	COG0203	ribosomal protein L17
LGL89_RS01105	COG0789	Transcriptional regulator
LGL89_RS01110	COG3036	rescue of stalled ribosome
LGL89_RS01115	COG1970	mechanosensitive ion channel activity
LGL89_RS01125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL89_RS01125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL89_RS01130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL89_RS01135	COG0242	peptide deformylase activity
LGL89_RS01140	COG0758	DNA mediated transformation
LGL89_RS01145	COG2922	Belongs to the Smg family
LGL89_RS01150	COG0551	DNA topoisomerase type I activity
LGL89_RS01155	COG0009	L-threonylcarbamoyladenylate synthase
LGL89_RS01165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL89_RS01190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL89_RS01195	COG3162	membrane
LGL89_RS01200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL89_RS01205	COG1301	dicarboxylic acid transport
LGL89_RS01215	COG1309	transcriptional regulator
LGL89_RS01220	COG4232	protein-disulfide reductase activity
LGL89_RS01230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL89_RS01260	COG1509	lysine 2,3-aminomutase activity
LGL89_RS01270	COG3397	chitin binding
LGL89_RS01290	COG3188	usher protein
LGL89_RS01310	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL89_RS01315	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL89_RS01320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL89_RS01325	COG1053	succinate dehydrogenase
LGL89_RS01330	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL89_RS01335	COG3264	Mechanosensitive ion channel
LGL89_RS01335	COG1511	domain protein
LGL89_RS01340	COG0688	phosphatidylethanolamine metabolic process
LGL89_RS01345	COG1162	GTPase activity
LGL89_RS01350	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL89_RS01370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL89_RS01375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL89_RS01375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL89_RS01380	COG0802	atpase or kinase
LGL89_RS01385	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL89_RS01395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL89_RS01405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL89_RS01410	COG0330	HflC and HflK could
LGL89_RS01415	COG0330	HflC and HflK could
LGL89_RS01420	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL89_RS01425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL89_RS01430	COG1959	2 iron, 2 sulfur cluster binding
LGL89_RS01435	COG0557	exoribonuclease II activity
LGL89_RS01440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL89_RS01460	COG3121	Chaperone
LGL89_RS01465	COG3188	usher protein
LGL89_RS01485	COG1073	alpha beta
LGL89_RS01495	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL89_RS01500	COG2965	DNA replication, synthesis of RNA primer
LGL89_RS01505	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL89_RS01510	COG0359	binds to the 23S rRNA
LGL89_RS01515	COG3061	Opacity-associated protein A
LGL89_RS01520	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL89_RS01530	COG0737	Belongs to the 5'-nucleotidase family
LGL89_RS01535	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL89_RS01540	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL89_RS01550	COG1253	flavin adenine dinucleotide binding
LGL89_RS01555	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL89_RS01560	COG0729	surface antigen
LGL89_RS01565	COG2911	Protein conserved in bacteria
LGL89_RS01570	COG2105	PFAM AIG2 family protein
LGL89_RS01575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL89_RS01585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL89_RS01600	COG3423	Transcriptional regulator
LGL89_RS01615	COG0142	geranyltranstransferase activity
LGL89_RS01630	COG0697	spore germination
LGL89_RS01635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL89_RS01640	COG0642	Histidine kinase
LGL89_RS01645	COG0745	RESPONSE REGULATOR receiver
LGL89_RS01650	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL89_RS01660	COG1534	Rna-binding protein
LGL89_RS01665	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL89_RS01675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL89_RS01680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL89_RS01685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL89_RS01705	COG0195	Participates in both transcription termination and antitermination
LGL89_RS01715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL89_RS01725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LGL89_RS01730	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL89_RS01740	COG0513	Belongs to the DEAD box helicase family
LGL89_RS01745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL89_RS01750	COG0814	amino acid
LGL89_RS01760	COG0826	peptidase U32
LGL89_RS01765	COG0826	peptidase U32
LGL89_RS01770	COG3154	lipid carrier protein
LGL89_RS01775	COG3153	acetyltransferase
LGL89_RS01780	COG2827	Endonuclease containing a URI domain
LGL89_RS01785	COG0531	amino acid
LGL89_RS01790	COG1982	Orn Lys Arg decarboxylase major
LGL89_RS01800	COG3787	Belongs to the UPF0306 family
LGL89_RS01805	COG0702	epimerase
LGL89_RS01810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL89_RS01815	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL89_RS01820	COG3454	Phosphonate metabolism
LGL89_RS01825	COG4778	phosphonate C-P lyase system protein PhnL
LGL89_RS01830	COG4107	phosphonate C-P lyase system protein PhnK
LGL89_RS01835	COG3627	carbon phosphorus lyase activity
LGL89_RS01840	COG3626	phosphonate metabolism
LGL89_RS01845	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL89_RS01850	COG3624	Phosphonate C-P lyase system protein PhnG
LGL89_RS01870	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL89_RS01885	COG2927	DNA polymerase III (CHI subunit)
LGL89_RS01890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL89_RS01895	COG0795	lipopolysaccharide-transporting ATPase activity
LGL89_RS01900	COG0795	lipopolysaccharide-transporting ATPase activity
LGL89_RS01910	COG0582	viral genome integration into host DNA
LGL89_RS01915	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LGL89_RS01935	COG1196	nuclear chromosome segregation
LGL89_RS01945	COG1401	restriction endodeoxyribonuclease activity
LGL89_RS02035	COG3077	Addiction module antitoxin, RelB DinJ family
LGL89_RS02125	COG5492	domain, Protein
LGL89_RS02145	COG3119	arylsulfatase activity
LGL89_RS02150	COG1349	DNA-binding transcription factor activity
LGL89_RS02160	COG2222	sugar isomerase
LGL89_RS02165	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL89_RS02170	COG3715	PTS system
LGL89_RS02175	COG3716	PTS system mannose fructose sorbose family IID component
LGL89_RS02185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL89_RS02195	COG1028	Short-chain dehydrogenase reductase Sdr
LGL89_RS02205	COG0641	radical SAM
LGL89_RS02210	COG3119	arylsulfatase activity
LGL89_RS02235	COG0859	PFAM glycosyl transferase family 9
LGL89_RS02250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL89_RS02255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL89_RS02265	COG2376	Dihydroxyacetone kinase
LGL89_RS02270	COG1461	Dihydroxyacetone kinase
LGL89_RS02275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL89_RS02275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL89_RS02275	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL89_RS02315	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL89_RS02330	COG2823	Periplasmic or secreted lipoprotein
LGL89_RS02340	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL89_RS02345	COG0084	hydrolase, TatD family'
LGL89_RS02350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL89_RS02365	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL89_RS02375	COG3726	membrane protein affecting hemolysin expression
LGL89_RS02380	COG0560	Phosphoserine phosphatase
LGL89_RS02395	COG0488	(ABC) transporter
LGL89_RS02415	COG0741	lytic transglycosylase activity
LGL89_RS02420	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL89_RS02425	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL89_RS02430	COG0406	alpha-ribazole phosphatase activity
LGL89_RS02435	COG2207	Transcriptional regulator
LGL89_RS02435	COG3708	Transcriptional regulator
LGL89_RS02440	COG3045	CreA protein
LGL89_RS02445	COG0745	RESPONSE REGULATOR receiver
LGL89_RS02480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL89_RS02485	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL89_RS02490	COG0477	Major facilitator Superfamily
LGL89_RS02500	COG1584	GPR1 FUN34 yaaH family protein
LGL89_RS02505	COG0443	Heat shock 70 kDa protein
LGL89_RS02515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL89_RS02520	COG0583	DNA-binding transcription factor activity
LGL89_RS02530	COG0196	riboflavin kinase activity
LGL89_RS02540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL89_RS02545	COG1047	Peptidyl-prolyl cis-trans
LGL89_RS02550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL89_RS02565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL89_RS02575	COG2966	Psort location CytoplasmicMembrane, score
LGL89_RS02600	COG2967	ApaG domain
LGL89_RS02605	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL89_RS02610	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL89_RS02620	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL89_RS02630	COG0564	pseudouridine synthase activity
LGL89_RS02635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL89_RS02640	COG0417	DNA replication proofreading
LGL89_RS02645	COG0586	Pfam SNARE associated Golgi protein
LGL89_RS02655	COG1178	ABC-type Fe3 transport system permease component
LGL89_RS02660	COG4143	(ABC) transporter
LGL89_RS02675	COG2814	Major facilitator Superfamily
LGL89_RS02685	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL89_RS02690	COG0473	3-isopropylmalate dehydrogenase activity
LGL89_RS02705	COG1022	Amp-dependent synthetase and ligase
LGL89_RS02710	COG0028	Belongs to the TPP enzyme family
LGL89_RS02730	COG0675	Transposase, IS605 OrfB family
LGL89_RS02745	COG0275	rRNA processing
LGL89_RS02750	COG3116	cell division
LGL89_RS02755	COG0768	penicillin binding
LGL89_RS02760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL89_RS02765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL89_RS02780	COG0772	Belongs to the SEDS family
LGL89_RS02785	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL89_RS02790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL89_RS02800	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LGL89_RS02805	COG0849	cell division
LGL89_RS02810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL89_RS02835	COG0494	nUDIX hydrolase
LGL89_RS02855	COG0516	GMP reductase activity
LGL89_RS02860	COG1459	type II secretion system
LGL89_RS02865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL89_RS02870	COG4969	Belongs to the N-Me-Phe pilin family
LGL89_RS02885	COG3725	Membrane protein required for beta-lactamase induction
LGL89_RS02890	COG1113	amino acid transport
LGL89_RS02895	COG2186	Transcriptional regulator
LGL89_RS02900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL89_RS02905	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL89_RS02910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL89_RS02920	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL89_RS02925	COG3112	Uncharacterised protein family (UPF0231)
LGL89_RS02940	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL89_RS02950	COG2132	Multicopper oxidase
LGL89_RS02960	COG0288	reversible hydration of carbon dioxide
LGL89_RS02965	COG1131	(ABC) transporter
LGL89_RS02970	COG0842	Transport permease protein
LGL89_RS02975	COG0726	polysaccharide deacetylase
LGL89_RS02980	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL89_RS02985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL89_RS02990	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL89_RS02995	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL89_RS03000	COG0617	tRNA 3'-terminal CCA addition
LGL89_RS03015	COG1489	DNA binding
LGL89_RS03020	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL89_RS03025	COG1643	Atp-dependent helicase
LGL89_RS03030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL89_RS03035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL89_RS03045	COG0316	Belongs to the HesB IscA family
LGL89_RS03050	COG2860	membrane
LGL89_RS03060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL89_RS03065	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL89_RS03070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL89_RS03080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL89_RS03085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL89_RS03090	COG3956	TIGRFAM MazG family protein
LGL89_RS03095	COG0504	CTP synthase activity
LGL89_RS03105	COG0602	queuosine metabolic process
LGL89_RS03110	COG0720	synthase
LGL89_RS03115	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL89_RS03125	COG0175	sulfate reduction
LGL89_RS03140	COG2234	aminopeptidase activity
LGL89_RS03145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL89_RS03145	COG1648	precorrin-2 dehydrogenase activity
LGL89_RS03150	COG0175	sulfate reduction
LGL89_RS03155	COG2895	sulfate adenylyltransferase (ATP) activity
LGL89_RS03160	COG0529	Catalyzes the synthesis of activated sulfate
LGL89_RS03170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL89_RS03180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL89_RS03185	COG0585	pseudouridine synthase activity
LGL89_RS03190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL89_RS03200	COG1388	LysM domain
LGL89_RS03200	COG4942	peptidase
LGL89_RS03205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL89_RS03210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL89_RS03280	COG2205	protein histidine kinase activity
LGL89_RS03280	COG0784	Response regulator, receiver
LGL89_RS03300	COG0741	lytic transglycosylase activity
LGL89_RS03425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL89_RS03445	COG3397	chitin binding
LGL89_RS03455	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL89_RS03500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL89_RS03510	COG3031	protein transport across the cell outer membrane
LGL89_RS03535	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL89_RS03535	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL89_RS03550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL89_RS03555	COG2137	regulation of response to DNA damage stimulus
LGL89_RS03560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL89_RS03565	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL89_RS03595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL89_RS03600	COG1238	metal cluster binding
LGL89_RS03605	COG2918	glutathione biosynthetic process
LGL89_RS03610	COG1854	S-ribosylhomocysteine lyase activity
LGL89_RS03615	COG4536	flavin adenine dinucleotide binding
LGL89_RS03620	COG4137	Cytochrome C assembly protein
LGL89_RS03625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL89_RS03635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL89_RS03640	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL89_RS03645	COG0335	large ribosomal subunit rRNA binding
LGL89_RS03650	COG3137	Salt-induced outer membrane protein
LGL89_RS03655	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL89_RS03660	COG3279	Response regulator of the LytR AlgR family
LGL89_RS03665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL89_RS03670	COG1605	Chorismate mutase
LGL89_RS03670	COG0287	Prephenate dehydrogenase
LGL89_RS03675	COG1605	Chorismate mutase
LGL89_RS03675	COG0077	Prephenate dehydratase
LGL89_RS03685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL89_RS03690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL89_RS03695	COG0564	pseudouridine synthase activity
LGL89_RS03700	COG1496	oxidoreductase activity
LGL89_RS03705	COG0542	response to heat
LGL89_RS03740	COG3021	interspecies interaction between organisms
LGL89_RS03745	COG0741	lytic transglycosylase activity
LGL89_RS03745	COG1388	LysM domain
LGL89_RS03755	COG2226	methyltransferase
LGL89_RS03765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL89_RS03775	COG1960	acyl-CoA dehydrogenase activity
LGL89_RS03780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL89_RS03785	COG0121	glutamine amidotransferase
LGL89_RS03790	COG3034	peptidoglycan biosynthetic process
LGL89_RS03800	COG1805	sodium ion transport
LGL89_RS03805	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL89_RS03810	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL89_RS03815	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL89_RS03825	COG1477	protein flavinylation
LGL89_RS03830	COG2991	Protein conserved in bacteria
LGL89_RS03840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL89_RS03845	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL89_RS03850	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL89_RS03855	COG1073	alpha beta
LGL89_RS03870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL89_RS03905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL89_RS03925	COG4126	flavin adenine dinucleotide binding
LGL89_RS03935	COG2974	May be involved in recombination
LGL89_RS03940	COG1940	carbohydrate kinase activity
LGL89_RS03945	COG0419	ATPase involved in DNA repair
LGL89_RS03950	COG0420	3'-5' exonuclease activity
LGL89_RS03955	COG0745	RESPONSE REGULATOR receiver
LGL89_RS03960	COG5002	protein histidine kinase activity
LGL89_RS03975	COG1113	amino acid transport
LGL89_RS03980	COG0366	Alpha amylase catalytic
LGL89_RS03985	COG0300	oxidoreductase activity
LGL89_RS03990	COG0450	alkyl hydroperoxide reductase
LGL89_RS03995	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL89_RS04010	COG1862	Preprotein translocase
LGL89_RS04015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL89_RS04020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL89_RS04025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL89_RS04030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL89_RS04030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL89_RS04035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL89_RS04045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL89_RS04050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL89_RS04055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL89_RS04060	COG0142	geranyltranstransferase activity
LGL89_RS04095	COG0693	protein deglycase activity
LGL89_RS04100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL89_RS04105	COG1666	GTP binding
LGL89_RS04110	COG2814	Major facilitator Superfamily
LGL89_RS04120	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL89_RS04125	COG1845	cytochrome c oxidase, subunit III
LGL89_RS04130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL89_RS04135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL89_RS04145	COG2223	nitrite transmembrane transporter activity
LGL89_RS04150	COG3056	Lipoprotein
LGL89_RS04155	COG0271	Belongs to the BolA IbaG family
LGL89_RS04165	COG0740	serine-type endopeptidase activity
LGL89_RS04170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL89_RS04175	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL89_RS04180	COG0776	regulation of translation
LGL89_RS04185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL89_RS04190	COG1555	photosystem II stabilization
LGL89_RS04195	COG0824	Thioesterase
LGL89_RS04200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL89_RS04205	COG4533	DNA binding
LGL89_RS04220	COG1522	sequence-specific DNA binding
LGL89_RS04225	COG1132	(ABC) transporter
LGL89_RS04230	COG1132	(ABC) transporter
LGL89_RS04235	COG0347	Belongs to the P(II) protein family
LGL89_RS04245	COG1946	Acyl-CoA thioesterase
LGL89_RS04250	COG3695	enzyme binding
LGL89_RS04275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL89_RS04280	COG0254	rRNA binding
LGL89_RS04285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL89_RS04290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL89_RS04295	COG1309	transcriptional regulator
LGL89_RS04300	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL89_RS04305	COG1196	nuclear chromosome segregation
LGL89_RS04305	COG3264	Mechanosensitive ion channel
LGL89_RS04320	COG2832	Protein of unknown function (DUF454)
LGL89_RS04325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL89_RS04365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL89_RS04370	COG0326	Molecular chaperone. Has ATPase activity
LGL89_RS04385	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL89_RS04390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL89_RS04395	COG4651	solute:proton antiporter activity
LGL89_RS04395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL89_RS04400	COG0737	Belongs to the 5'-nucleotidase family
LGL89_RS04415	COG0500	methyltransferase
LGL89_RS04445	COG1086	Polysaccharide biosynthesis protein
LGL89_RS04455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL89_RS04460	COG3735	TraB family
LGL89_RS04465	COG2217	Heavy metal translocating P-type atpase
LGL89_RS04470	COG0789	Transcriptional regulator
LGL89_RS04475	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL89_RS04480	COG0330	HflC and HflK could
LGL89_RS04485	COG3118	belongs to the thioredoxin family
LGL89_RS04490	COG0300	oxidoreductase activity
LGL89_RS04495	COG2755	lipolytic protein G-D-S-L family
LGL89_RS04500	COG4181	ATPase activity
LGL89_RS04505	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL89_RS04510	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL89_RS04515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL89_RS04520	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL89_RS04525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL89_RS04550	COG3188	usher protein
LGL89_RS04555	COG3121	Chaperone
LGL89_RS04585	COG2501	S4 domain
LGL89_RS04590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL89_RS04650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL89_RS04655	COG1393	Belongs to the ArsC family
LGL89_RS04665	COG1022	Amp-dependent synthetase and ligase
LGL89_RS04675	COG1028	Short-chain dehydrogenase reductase Sdr
LGL89_RS04690	COG3038	cytochrome b561
LGL89_RS04720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL89_RS04730	COG1215	transferase activity, transferring glycosyl groups
LGL89_RS04750	COG3250	beta-galactosidase activity
LGL89_RS04765	COG1309	transcriptional regulator
LGL89_RS04795	COG2197	response regulator
LGL89_RS04800	COG1278	Cold shock
LGL89_RS04820	COG3706	GGDEF domain
LGL89_RS04830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL89_RS04840	COG2921	Belongs to the UPF0250 family
LGL89_RS04845	COG1686	Belongs to the peptidase S11 family
LGL89_RS04850	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL89_RS04855	COG0772	Belongs to the SEDS family
LGL89_RS04860	COG0768	penicillin binding
LGL89_RS04865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL89_RS04870	COG0799	negative regulation of ribosome biogenesis
LGL89_RS04875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL89_RS04880	COG1466	dna polymerase III delta subunit
LGL89_RS04885	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL89_RS04895	COG2888	peptidyl-tyrosine sulfation
LGL89_RS04900	COG1126	abc transporter atp-binding protein
LGL89_RS04905	COG0765	amino acid transport
LGL89_RS04910	COG0765	amino acid transport
LGL89_RS04920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL89_RS04925	COG4535	Mg2 and Co2 transporter CorC
LGL89_RS04930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL89_RS04935	COG1702	phosphate starvation-inducible protein PhoH
LGL89_RS04940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL89_RS04945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL89_RS04980	COG0367	asparagine synthase
LGL89_RS04985	COG0647	UMP catabolic process
LGL89_RS04990	COG1940	carbohydrate kinase activity
LGL89_RS04990	COG1846	Transcriptional regulator
LGL89_RS04995	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL89_RS05005	COG1263	PTS System
LGL89_RS05005	COG2190	(PTS) system
LGL89_RS05005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL89_RS05030	COG0735	belongs to the Fur family
LGL89_RS05040	COG0840	transmembrane signaling receptor activity
LGL89_RS05050	COG0596	Alpha beta hydrolase
LGL89_RS05055	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL89_RS05060	COG0033	Phosphoglucomutase
LGL89_RS05070	COG0745	RESPONSE REGULATOR receiver
LGL89_RS05075	COG2205	protein histidine kinase activity
LGL89_RS05080	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL89_RS05085	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL89_RS05105	COG3272	Protein of unknown function (DUF1722)
LGL89_RS05110	COG0415	Belongs to the DNA photolyase family
LGL89_RS05115	COG5212	phosphodiesterase
LGL89_RS05120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL89_RS05125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL89_RS05130	COG1984	allophanate hydrolase subunit 2
LGL89_RS05135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL89_RS05170	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL89_RS05175	COG1053	succinate dehydrogenase
LGL89_RS05180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL89_RS05185	COG0567	Dehydrogenase, E1 component
LGL89_RS05190	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL89_RS05195	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL89_RS05200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL89_RS05205	COG0737	Belongs to the 5'-nucleotidase family
LGL89_RS05210	COG1271	oxidase subunit
LGL89_RS05215	COG1294	oxidase, subunit
LGL89_RS05220	COG4890	Cyd operon protein YbgT
LGL89_RS05225	COG3790	cyd operon protein YbgE
LGL89_RS05230	COG0824	Thioesterase
LGL89_RS05235	COG0811	peptide transport
LGL89_RS05240	COG0848	biopolymer transport protein
LGL89_RS05245	COG3064	Membrane
LGL89_RS05245	COG3064	Membrane
LGL89_RS05250	COG0823	Involved in the tonB-independent uptake of proteins
LGL89_RS05255	COG2885	chlorophyll binding
LGL89_RS05260	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL89_RS05300	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL89_RS05310	COG2205	protein histidine kinase activity
LGL89_RS05310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL89_RS05320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL89_RS05325	COG0588	phosphoglycerate mutase activity
LGL89_RS05335	COG2017	converts alpha-aldose to the beta-anomer
LGL89_RS05345	COG1085	galactose-1-phosphate uridylyltransferase
LGL89_RS05350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL89_RS05365	COG3585	molybdate ion transport
LGL89_RS05365	COG2005	Transcriptional regulator
LGL89_RS05375	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL89_RS05380	COG4149	molybdate abc transporter
LGL89_RS05390	COG0561	phosphatase activity
LGL89_RS05395	COG2706	6-phosphogluconolactonase activity
LGL89_RS05410	COG0156	8-amino-7-oxononanoate synthase activity
LGL89_RS05415	COG2226	methyltransferase
LGL89_RS05430	COG0556	nucleotide-excision repair
LGL89_RS05435	COG4628	conserved protein (DUF2132)
LGL89_RS05450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL89_RS05455	COG1120	ATPase activity
LGL89_RS05460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL89_RS05465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL89_RS05475	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL89_RS05480	COG0314	molybdopterin synthase activity
LGL89_RS05485	COG0670	Belongs to the BI1 family
LGL89_RS05490	COG0842	Transport permease protein
LGL89_RS05495	COG0842	Transport permease protein
LGL89_RS05500	COG1131	(ABC) transporter
LGL89_RS05505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL89_RS05510	COG1309	transcriptional regulator
LGL89_RS05515	COG0513	Belongs to the DEAD box helicase family
LGL89_RS05520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL89_RS05530	COG1686	Belongs to the peptidase S11 family
LGL89_RS05535	COG0277	FAD linked oxidase domain protein
LGL89_RS05555	COG2261	transglycosylase associated protein
LGL89_RS05565	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL89_RS05575	COG3639	organic phosphonate transmembrane transporter activity
LGL89_RS05580	COG4807	Protein conserved in bacteria
LGL89_RS05585	COG2897	thiosulfate sulfurtransferase activity
LGL89_RS05590	COG1732	Glycine betaine
LGL89_RS05595	COG1174	glycine betaine transport
LGL89_RS05600	COG1125	glycine betaine transport
LGL89_RS05605	COG1174	glycine betaine transport
LGL89_RS05610	COG0531	amino acid
LGL89_RS05615	COG1982	Orn Lys Arg decarboxylase major
LGL89_RS05625	COG0697	spore germination
LGL89_RS05640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL89_RS05645	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL89_RS05650	COG1126	abc transporter atp-binding protein
LGL89_RS05655	COG0765	amino acid transport
LGL89_RS05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL89_RS05680	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL89_RS05685	COG2239	Acts as a magnesium transporter
LGL89_RS05690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL89_RS05695	COG0488	(ABC) transporter
LGL89_RS05700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL89_RS05705	COG0303	'Molybdopterin
LGL89_RS05725	COG0583	DNA-binding transcription factor activity
LGL89_RS05730	COG0477	Major facilitator Superfamily
LGL89_RS05735	COG0302	gtp cyclohydrolase
LGL89_RS05740	COG2311	Membrane
LGL89_RS05765	COG2949	membrane
LGL89_RS05770	COG0281	malic enzyme
LGL89_RS05780	COG0583	DNA-binding transcription factor activity
LGL89_RS05790	COG1346	cytolysis
LGL89_RS05795	COG1380	Effector of murein hydrolase LrgA
LGL89_RS05805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL89_RS05805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL89_RS05810	COG0489	protein tyrosine kinase activity
LGL89_RS05815	COG0572	uridine kinase
LGL89_RS05820	COG0717	Belongs to the dCTP deaminase family
LGL89_RS05825	COG2982	Protein involved in outer membrane biogenesis
LGL89_RS05830	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL89_RS05835	COG1253	flavin adenine dinucleotide binding
LGL89_RS05840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL89_RS05845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL89_RS05850	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL89_RS05860	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL89_RS05860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL89_RS05870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL89_RS05880	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL89_RS05880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL89_RS05885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL89_RS05890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL89_RS05905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL89_RS05910	COG0625	glutathione transferase activity
LGL89_RS05925	COG0626	cystathionine gamma-synthase activity
LGL89_RS05935	COG1686	Belongs to the peptidase S11 family
LGL89_RS05940	COG1760	l-serine dehydratase
LGL89_RS05945	COG0814	amino acid
LGL89_RS05950	COG1349	DNA-binding transcription factor activity
LGL89_RS05960	COG0671	phosphoesterase, PA-phosphatase related
LGL89_RS06025	COG0569	domain protein
LGL89_RS06025	COG2985	domain, Protein
LGL89_RS06045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL89_RS06050	COG3842	ATPase activity
LGL89_RS06055	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL89_RS06060	COG1177	transmembrane transport
LGL89_RS06075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL89_RS06080	COG4160	amino acid transport
LGL89_RS06085	COG4215	(ABC) transporter
LGL89_RS06090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL89_RS06095	COG1126	abc transporter atp-binding protein
LGL89_RS06105	COG0393	Putative heavy-metal-binding
LGL89_RS06110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL89_RS06115	COG0702	epimerase
LGL89_RS06120	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL89_RS06125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL89_RS06130	COG1151	hydroxylamine reductase activity
LGL89_RS06135	COG2431	L-lysine efflux transmembrane transporter activity
LGL89_RS06140	COG3593	DNA synthesis involved in DNA repair
LGL89_RS06145	COG2990	Protein conserved in bacteria
LGL89_RS06150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL89_RS06160	COG1278	Cold shock
LGL89_RS06165	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL89_RS06170	COG0542	response to heat
LGL89_RS06175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL89_RS06185	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL89_RS06195	COG0492	ferredoxin-NADP+ reductase activity
LGL89_RS06200	COG1522	sequence-specific DNA binding
LGL89_RS06205	COG3107	peptidoglycan biosynthetic process
LGL89_RS06205	COG1674	ftsk spoiiie
LGL89_RS06210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL89_RS06215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL89_RS06220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL89_RS06225	COG2814	Major facilitator Superfamily
LGL89_RS06230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL89_RS06235	COG1882	Formate acetyltransferase
LGL89_RS06240	COG2116	formate transmembrane transporter activity
LGL89_RS06245	COG1944	ATP diphosphatase activity
LGL89_RS06250	COG0252	asparaginase activity
LGL89_RS06260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL89_RS06270	COG0539	negative regulation of cytoplasmic translation
LGL89_RS06280	COG0658	competence protein
LGL89_RS06280	COG2333	competence protein COMEC
LGL89_RS06290	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL89_RS06295	COG5383	Protein conserved in bacteria
LGL89_RS06305	COG1278	Cold shock
LGL89_RS06310	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL89_RS06315	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL89_RS06320	COG3173	Aminoglycoside phosphotransferase
LGL89_RS06325	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL89_RS06330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL89_RS06335	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL89_RS06345	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL89_RS06350	COG2989	Protein conserved in bacteria
LGL89_RS06355	COG3108	Peptidase M15
LGL89_RS06360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL89_RS06365	COG1448	Aminotransferase
LGL89_RS06380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL89_RS06385	COG0308	aminopeptidase N
LGL89_RS06390	COG0167	dihydroorotate dehydrogenase activity
LGL89_RS06400	COG0633	Ferredoxin
LGL89_RS06400	COG3217	Mosc domain protein beta barrel domain protein
LGL89_RS06405	COG0116	Belongs to the methyltransferase superfamily
LGL89_RS06405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL89_RS06410	COG0488	(ABC) transporter
LGL89_RS06415	COG2995	paraquat-inducible protein a
LGL89_RS06420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL89_RS06420	COG3008	intermembrane lipid transfer
LGL89_RS06425	COG3009	Protein conserved in bacteria
LGL89_RS06430	COG3130	regulation of translation
LGL89_RS06435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL89_RS06440	COG1067	ATP-dependent peptidase activity
LGL89_RS06445	COG3120	sequence-specific DNA binding
LGL89_RS06455	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL89_RS06460	COG3070	regulator of competence-specific genes
LGL89_RS06465	COG1289	transmembrane transporter activity
LGL89_RS06470	COG3304	Inner membrane component domain
LGL89_RS06475	COG0210	DNA helicase
LGL89_RS06480	COG1803	Methylglyoxal synthase
LGL89_RS06490	COG1832	CoA-binding protein
LGL89_RS06495	COG3785	DNA binding
LGL89_RS06500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL89_RS06505	COG1254	Belongs to the acylphosphatase family
LGL89_RS06510	COG2920	part of a sulfur-relay system
LGL89_RS06520	COG0288	reversible hydration of carbon dioxide
LGL89_RS06540	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL89_RS06545	COG2943	transferase activity, transferring hexosyl groups
LGL89_RS06570	COG1560	Kdo2-lipid A biosynthetic process
LGL89_RS06580	COG0628	permease
LGL89_RS06605	COG0418	dihydroorotase activity
LGL89_RS06610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGL89_RS06620	COG1530	ribonuclease E activity
LGL89_RS06625	COG0564	pseudouridine synthase activity
LGL89_RS06630	COG0424	maF-like protein
LGL89_RS06635	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL89_RS06640	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL89_RS06650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL89_RS06655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL89_RS06665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL89_RS06670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL89_RS06675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL89_RS06680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL89_RS06685	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL89_RS06690	COG0470	DNA polymerase III
LGL89_RS06695	COG0084	hydrolase, TatD family'
LGL89_RS06700	COG1263	PTS System
LGL89_RS06700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL89_RS06705	COG0537	adenosine 5'-monophosphoramidase activity
LGL89_RS06710	COG5633	Lipoprotein
LGL89_RS06715	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL89_RS06730	COG3150	esterase
LGL89_RS06735	COG1252	NADH dehydrogenase
LGL89_RS06740	COG3134	Outer membrane lipoprotein
LGL89_RS06745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL89_RS06750	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL89_RS06760	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL89_RS06780	COG2850	peptidyl-arginine hydroxylation
LGL89_RS06785	COG2205	protein histidine kinase activity
LGL89_RS06790	COG0745	RESPONSE REGULATOR receiver
LGL89_RS06800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL89_RS06810	COG0482	sulfurtransferase activity
LGL89_RS06820	COG1187	pseudouridine synthase activity
LGL89_RS06825	COG0538	isocitrate dehydrogenase activity
LGL89_RS06830	COG2771	luxR family
LGL89_RS06835	COG3916	Acyl-homoserine-lactone synthase
LGL89_RS06840	COG2723	6-phospho-beta-galactosidase activity
LGL89_RS06850	COG0339	signal peptide processing
LGL89_RS06855	COG0840	transmembrane signaling receptor activity
LGL89_RS06860	COG3493	citrate carrier protein
LGL89_RS06865	COG4565	transcriptional regulatory protein
LGL89_RS06870	COG3290	protein histidine kinase activity
LGL89_RS06875	COG0471	metal ion transport
LGL89_RS06915	COG4977	sequence-specific DNA binding
LGL89_RS06920	COG1702	phosphate starvation-inducible protein PhoH
LGL89_RS06925	COG0387	Pfam Sodium calcium exchanger
LGL89_RS06930	COG2375	cellular response to nickel ion
LGL89_RS06935	COG3850	Histidine kinase
LGL89_RS06945	COG1294	oxidase, subunit
LGL89_RS06950	COG1271	oxidase subunit
LGL89_RS06955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL89_RS06960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL89_RS06965	COG3138	arginine N-succinyltransferase
LGL89_RS06975	COG3724	N-succinylarginine dihydrolase activity
LGL89_RS06995	COG1228	amidohydrolase
LGL89_RS07005	COG0402	S-adenosylhomocysteine deaminase activity
LGL89_RS07025	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL89_RS07030	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL89_RS07035	COG3383	formate dehydrogenase (NAD+) activity
LGL89_RS07040	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL89_RS07045	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL89_RS07055	COG3260	NADH ubiquinone oxidoreductase 20
LGL89_RS07060	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL89_RS07065	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL89_RS07065	COG3261	NADH dehydrogenase
LGL89_RS07070	COG0650	Formate hydrogenlyase subunit 4
LGL89_RS07075	COG0651	ATP synthesis coupled electron transport
LGL89_RS07080	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL89_RS07090	COG0375	protein maturation
LGL89_RS07095	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL89_RS07100	COG0298	carbon dioxide binding
LGL89_RS07105	COG0409	Hydrogenase expression formation protein
LGL89_RS07110	COG0309	Hydrogenase expression formation protein (HypE)
LGL89_RS07130	COG0012	GTP binding
LGL89_RS07140	COG0193	aminoacyl-tRNA hydrolase activity
LGL89_RS07150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL89_RS07160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL89_RS07165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL89_RS07170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL89_RS07175	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL89_RS07190	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL89_RS07195	COG0659	secondary active sulfate transmembrane transporter activity
LGL89_RS07200	COG3706	GGDEF domain
LGL89_RS07225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL89_RS07235	COG3381	protein complex oligomerization
LGL89_RS07255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL89_RS07265	COG0673	inositol 2-dehydrogenase activity
LGL89_RS07270	COG0728	peptidoglycan biosynthetic process
LGL89_RS07300	COG3102	Protein conserved in bacteria
LGL89_RS07305	COG3142	Participates in the control of copper homeostasis
LGL89_RS07320	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL89_RS07325	COG1801	Protein of unknown function DUF72
LGL89_RS07335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL89_RS07340	COG0494	nUDIX hydrolase
LGL89_RS07350	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL89_RS07360	COG2255	four-way junction helicase activity
LGL89_RS07365	COG3104	oligopeptide transport
LGL89_RS07370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL89_RS07375	COG1121	(ABC) transporter
LGL89_RS07380	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL89_RS07385	COG0739	heme binding
LGL89_RS07390	COG1560	Kdo2-lipid A biosynthetic process
LGL89_RS07395	COG0469	pyruvate kinase activity
LGL89_RS07400	COG1737	Transcriptional regulator
LGL89_RS07405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL89_RS07410	COG0800	Aldolase
LGL89_RS07420	COG2076	Multidrug Resistance protein
LGL89_RS07425	COG0251	oxidation-reduction process
LGL89_RS07430	COG1199	ATP-dependent helicase activity
LGL89_RS07435	COG1214	PFAM Peptidase M22, glycoprotease
LGL89_RS07445	COG0318	PFAM AMP-dependent synthetase and ligase
LGL89_RS07450	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL89_RS07455	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL89_RS07460	COG2894	cell division
LGL89_RS07465	COG0850	regulation of cytokinetic process
LGL89_RS07470	COG3100	YcgL domain-containing protein
LGL89_RS07475	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL89_RS07480	COG2983	Belongs to the UPF0260 family
LGL89_RS07500	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL89_RS07510	COG2719	SpoVR family
LGL89_RS07515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL89_RS07520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL89_RS07525	COG2814	Major facilitator Superfamily
LGL89_RS07535	COG2202	Pas domain
LGL89_RS07535	COG2200	EAL domain
LGL89_RS07535	COG2199	diguanylate cyclase activity
LGL89_RS07555	COG2718	Belongs to the UPF0229 family
LGL89_RS07560	COG2766	serine protein kinase
LGL89_RS07570	COG3713	MltA-interacting MipA family protein
LGL89_RS07590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL89_RS07595	COG3139	Protein of unknown function (DUF1315)
LGL89_RS07600	COG1335	isochorismatase
LGL89_RS07605	COG0252	asparaginase activity
LGL89_RS07610	COG0616	signal peptide processing
LGL89_RS07615	COG0778	Nitroreductase
LGL89_RS07625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL89_RS07635	COG0494	nUDIX hydrolase
LGL89_RS07640	COG0708	Exodeoxyribonuclease III
LGL89_RS07665	COG0788	formyltetrahydrofolate deformylase activity
LGL89_RS07675	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL89_RS07680	COG0745	RESPONSE REGULATOR receiver
LGL89_RS07700	COG1454	alcohol dehydrogenase
LGL89_RS07700	COG1012	belongs to the aldehyde dehydrogenase family
LGL89_RS07705	COG2095	MarC family integral membrane protein
LGL89_RS07710	COG4166	transmembrane transport
LGL89_RS07725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL89_RS07740	COG3099	Belongs to the UPF0263 family
LGL89_RS07745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL89_RS07765	COG2350	Protein conserved in bacteria
LGL89_RS07780	COG3710	Transcriptional regulator
LGL89_RS07815	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL89_RS07840	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL89_RS07845	COG3047	cAMP biosynthetic process
LGL89_RS07860	COG0133	tryptophan synthase activity
LGL89_RS07865	COG0135	phosphoribosylanthranilate isomerase activity
LGL89_RS07865	COG0134	indole-3-glycerol-phosphate synthase activity
LGL89_RS07875	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL89_RS07885	COG0613	PHP domain protein
LGL89_RS07890	COG0009	L-threonylcarbamoyladenylate synthase
LGL89_RS07895	COG1187	pseudouridine synthase activity
LGL89_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
LGL89_RS07910	COG0616	signal peptide processing
LGL89_RS07925	COG0583	DNA-binding transcription factor activity
LGL89_RS07940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL89_RS07950	COG0671	phosphoesterase, PA-phosphatase related
LGL89_RS07955	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL89_RS07960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL89_RS07980	COG0023	Translation Initiation Factor
LGL89_RS07990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL89_RS07995	COG5002	protein histidine kinase activity
LGL89_RS07995	COG5001	Diguanylate cyclase
LGL89_RS07995	COG3447	MASE1 domain protein
LGL89_RS08000	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL89_RS08005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL89_RS08015	COG4659	FMN binding
LGL89_RS08025	COG3708	Transcriptional regulator
LGL89_RS08025	COG2207	Transcriptional regulator
LGL89_RS08030	COG4656	Part of a membrane complex involved in electron transport
LGL89_RS08045	COG4657	Part of a membrane complex involved in electron transport
LGL89_RS08055	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL89_RS08065	COG0673	inositol 2-dehydrogenase activity
LGL89_RS08070	COG0385	Bile acid
LGL89_RS08075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL89_RS08080	COG5339	Protein conserved in bacteria
LGL89_RS08085	COG1482	cell wall glycoprotein biosynthetic process
LGL89_RS08090	COG0114	fumarate hydratase activity
LGL89_RS08100	COG1940	carbohydrate kinase activity
LGL89_RS08105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL89_RS08125	COG1742	UPF0060 membrane protein
LGL89_RS08130	COG4221	oxidoreductase activity
LGL89_RS08135	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL89_RS08155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL89_RS08195	COG1011	Hydrolase
LGL89_RS08205	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL89_RS08210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL89_RS08215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL89_RS08220	COG0589	response to stress
LGL89_RS08250	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL89_RS08255	COG3623	hexulose-6-phosphate isomerase
LGL89_RS08260	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL89_RS08265	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL89_RS08275	COG0531	amino acid
LGL89_RS08285	COG0745	RESPONSE REGULATOR receiver
LGL89_RS08290	COG2205	protein histidine kinase activity
LGL89_RS08305	COG2207	Transcriptional regulator
LGL89_RS08310	COG1881	PFAM PEBP family protein
LGL89_RS08320	COG3591	Belongs to the peptidase S1B family
LGL89_RS08325	COG1643	Atp-dependent helicase
LGL89_RS08330	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL89_RS08335	COG3784	Protein of unknown function (DUF1318)
LGL89_RS08350	COG2911	Protein conserved in bacteria
LGL89_RS08355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL89_RS08360	COG3187	Heat shock protein
LGL89_RS08365	COG3042	response to heat
LGL89_RS08370	COG1285	pathogenesis
LGL89_RS08380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL89_RS08380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL89_RS08380	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL89_RS08380	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL89_RS08395	COG4166	transmembrane transport
LGL89_RS08400	COG2866	Carboxypeptidase
LGL89_RS08405	COG4948	Mandelate Racemase Muconate Lactonizing
LGL89_RS08410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL89_RS08420	COG5642	Protein of unknown function (DUF2384)
LGL89_RS08425	COG5654	RES domain protein
LGL89_RS08430	COG3768	UPF0283 membrane protein
LGL89_RS08435	COG3106	COG3106 Predicted ATPase
LGL89_RS08445	COG1983	PspC domain protein
LGL89_RS08455	COG1842	Phage shock protein A
LGL89_RS08460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LGL89_RS08475	COG4166	transmembrane transport
LGL89_RS08485	COG4171	peptide transport system, permease
LGL89_RS08490	COG4172	Belongs to the ABC transporter superfamily
LGL89_RS08495	COG4172	Belongs to the ABC transporter superfamily
LGL89_RS08505	COG3104	oligopeptide transport
LGL89_RS08515	COG0484	heat shock protein binding
LGL89_RS08560	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL89_RS08565	COG3133	Outer membrane lipoprotein
LGL89_RS08570	COG1846	Transcriptional regulator
LGL89_RS08580	COG4989	oxidoreductase activity
LGL89_RS08585	COG3313	Fe-S protein
LGL89_RS08590	COG2194	sulfuric ester hydrolase activity
LGL89_RS08595	COG1309	transcriptional regulator
LGL89_RS08600	COG1902	pentaerythritol trinitrate reductase activity
LGL89_RS08615	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL89_RS08620	COG0791	NLP P60 protein
LGL89_RS08625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL89_RS08635	COG1609	Transcriptional regulator
LGL89_RS08640	COG0583	DNA-binding transcription factor activity
LGL89_RS08645	COG2814	Major facilitator Superfamily
LGL89_RS08650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL89_RS08655	COG0307	riboflavin synthase, alpha
LGL89_RS08690	COG1376	ErfK ybiS ycfS ynhG family protein
LGL89_RS08690	COG1388	LysM domain
LGL89_RS08695	COG2166	iron-sulfur cluster assembly
LGL89_RS08705	COG0719	Fe-S assembly protein
LGL89_RS08710	COG0396	ATPase activity
LGL89_RS08715	COG0719	Fe-S assembly protein
LGL89_RS08720	COG0316	Belongs to the HesB IscA family
LGL89_RS08725	COG2050	protein possibly involved in aromatic compounds catabolism
LGL89_RS08730	COG0247	lactate metabolic process
LGL89_RS08730	COG0277	FAD linked oxidase domain protein
LGL89_RS08735	COG0628	permease
LGL89_RS08745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL89_RS08745	COG0574	Belongs to the PEP-utilizing enzyme family
LGL89_RS08750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL89_RS08755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL89_RS08765	COG4771	TonB-dependent receptor
LGL89_RS08770	COG3720	iron ion transport
LGL89_RS08775	COG4558	Periplasmic binding protein
LGL89_RS08780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL89_RS08785	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL89_RS08795	COG0095	Lipoate-protein ligase
LGL89_RS08800	COG0791	NLP P60 protein
LGL89_RS08805	COG2076	Multidrug Resistance protein
LGL89_RS08810	COG2076	Multidrug Resistance protein
LGL89_RS08815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL89_RS08830	COG0463	Glycosyl transferase, family 2
LGL89_RS08835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL89_RS08845	COG4139	cobalamin transport
LGL89_RS08850	COG4974	Belongs to the 'phage' integrase family
LGL89_RS08870	COG2314	TM2 domain
LGL89_RS08875	COG0776	regulation of translation
LGL89_RS08945	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL89_RS08950	COG1121	(ABC) transporter
LGL89_RS08955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL89_RS08960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL89_RS08965	COG3001	Fructosamine kinase
LGL89_RS08975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL89_RS08980	COG1988	membrane-bound metal-dependent
LGL89_RS08985	COG1823	symporter activity
LGL89_RS08990	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL89_RS09000	COG2814	Major facilitator Superfamily
LGL89_RS09010	COG0501	Belongs to the peptidase M48B family
LGL89_RS09015	COG0793	Belongs to the peptidase S41A family
LGL89_RS09025	COG1956	GAF domain-containing protein
LGL89_RS09030	COG2995	paraquat-inducible protein a
LGL89_RS09035	COG3008	intermembrane lipid transfer
LGL89_RS09040	COG2203	Gaf domain
LGL89_RS09040	COG4251	negative regulation of phosphorylation
LGL89_RS09040	COG5001	Diguanylate cyclase
LGL89_RS09040	COG3706	GGDEF domain
LGL89_RS09125	COG1276	copper resistance
LGL89_RS09130	COG2372	response to copper ion
LGL89_RS09135	COG1528	Iron-storage protein
LGL89_RS09150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL89_RS09155	COG1770	oligopeptidase
LGL89_RS09165	COG3097	Belongs to the UPF0267 family
LGL89_RS09170	COG3141	response to X-ray
LGL89_RS09175	COG0513	Belongs to the DEAD box helicase family
LGL89_RS09195	COG0494	nUDIX hydrolase
LGL89_RS09200	COG1760	l-serine dehydratase
LGL89_RS09210	COG1253	flavin adenine dinucleotide binding
LGL89_RS09215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL89_RS09215	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL89_RS09220	COG3715	PTS system
LGL89_RS09225	COG3716	PTS system mannose fructose sorbose family IID component
LGL89_RS09230	COG4811	Protein of unknown function (DUF986)
LGL89_RS09235	COG1971	Probably functions as a manganese efflux pump
LGL89_RS09255	COG1960	acyl-CoA dehydrogenase activity
LGL89_RS09265	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL89_RS09295	COG2226	methyltransferase
LGL89_RS09305	COG1496	oxidoreductase activity
LGL89_RS09325	COG1113	amino acid transport
LGL89_RS09360	COG2207	Transcriptional regulator
LGL89_RS09380	COG1132	(ABC) transporter
LGL89_RS09390	COG5001	Diguanylate cyclase
LGL89_RS09390	COG2203	Gaf domain
LGL89_RS09390	COG4251	negative regulation of phosphorylation
LGL89_RS09390	COG3706	GGDEF domain
LGL89_RS09410	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL89_RS09430	COG1278	Cold shock
LGL89_RS09435	COG1278	Cold shock
LGL89_RS09440	COG1278	Cold shock
LGL89_RS09455	COG2169	Transcriptional regulator
LGL89_RS09455	COG1917	Cupin 2, conserved barrel domain protein
LGL89_RS09460	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL89_RS09465	COG2723	6-phospho-beta-galactosidase activity
LGL89_RS09470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL89_RS09475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL89_RS09480	COG1187	pseudouridine synthase activity
LGL89_RS09490	COG3122	Protein conserved in bacteria
LGL89_RS09495	COG1757	Na H antiporter
LGL89_RS09510	COG2235	arginine
LGL89_RS09525	COG0076	glutamate decarboxylase activity
LGL89_RS09530	COG0531	amino acid
LGL89_RS09565	COG2153	protein acetylation
LGL89_RS09570	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL89_RS09605	COG0840	transmembrane signaling receptor activity
LGL89_RS09610	COG2801	Transposase and inactivated derivatives
LGL89_RS09630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL89_RS09635	COG0322	excinuclease ABC activity
LGL89_RS09640	COG2197	response regulator
LGL89_RS09665	COG1113	amino acid transport
LGL89_RS09675	COG0531	amino acid
LGL89_RS09680	COG3710	Transcriptional regulator
LGL89_RS09685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL89_RS09690	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL89_RS09690	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL89_RS09690	COG0506	proline dehydrogenase activity
LGL89_RS09695	COG1126	abc transporter atp-binding protein
LGL89_RS09700	COG0765	amino acid transport
LGL89_RS09705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL89_RS09710	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL89_RS09720	COG1191	sigma factor activity
LGL89_RS09760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL89_RS09765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL89_RS09780	COG1677	Flagellar hook-basal body complex protein FliE
LGL89_RS09790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL89_RS09800	COG1157	protein secretion by the type III secretion system
LGL89_RS09815	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL89_RS09895	COG1558	bacterial-type flagellum-dependent cell motility
LGL89_RS09900	COG1815	bacterial-type flagellum-dependent cell motility
LGL89_RS09910	COG2747	anti-sigma28 factor FlgM
LGL89_RS09915	COG3418	PFAM FlgN family protein
LGL89_RS09925	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL89_RS09930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL89_RS09940	COG2197	response regulator
LGL89_RS09955	COG3188	usher protein
LGL89_RS09960	COG3121	Chaperone
LGL89_RS09970	COG3539	Fimbrial protein
LGL89_RS09995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL89_RS10000	COG0745	RESPONSE REGULATOR receiver
LGL89_RS10010	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL89_RS10015	COG0840	transmembrane signaling receptor activity
LGL89_RS10020	COG0840	transmembrane signaling receptor activity
LGL89_RS10025	COG0835	chemotaxis
LGL89_RS10030	COG2198	Histidine kinase
LGL89_RS10030	COG0643	Histidine kinase
LGL89_RS10035	COG1360	Flagellar Motor Protein
LGL89_RS10055	COG0589	response to stress
LGL89_RS10060	COG1285	pathogenesis
LGL89_RS10065	COG0840	transmembrane signaling receptor activity
LGL89_RS10080	COG1609	Transcriptional regulator
LGL89_RS10090	COG3321	synthase
LGL89_RS10090	COG1028	Short-chain dehydrogenase reductase Sdr
LGL89_RS10090	COG0604	alcohol dehydrogenase
LGL89_RS10140	COG0471	metal ion transport
LGL89_RS10155	COG3051	citrate lyase alpha subunit
LGL89_RS10160	COG2301	Belongs to the HpcH HpaI aldolase family
LGL89_RS10165	COG3052	prosthetic group binding
LGL89_RS10170	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL89_RS10175	COG3290	protein histidine kinase activity
LGL89_RS10180	COG4565	transcriptional regulatory protein
LGL89_RS10195	COG2271	Major facilitator Superfamily
LGL89_RS10200	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL89_RS10210	COG3842	ATPase activity
LGL89_RS10235	COG1289	transmembrane transporter activity
LGL89_RS10245	COG2925	Exonuclease
LGL89_RS10250	COG0531	amino acid
LGL89_RS10255	COG4771	TonB-dependent receptor
LGL89_RS10265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL89_RS10275	COG0833	amino acid
LGL89_RS10280	COG0583	DNA-binding transcription factor activity
LGL89_RS10290	COG2855	membrane
LGL89_RS10295	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL89_RS10300	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL89_RS10300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL89_RS10300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL89_RS10305	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL89_RS10320	COG3005	denitrification pathway
LGL89_RS10325	COG0243	molybdopterin cofactor binding
LGL89_RS10340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL89_RS10350	COG0246	Mannitol dehydrogenase
LGL89_RS10360	COG0523	cobalamin synthesis protein
LGL89_RS10365	COG0671	phosphoesterase, PA-phosphatase related
LGL89_RS10370	COG0791	NLP P60 protein
LGL89_RS10375	COG2200	EAL domain
LGL89_RS10380	COG4166	transmembrane transport
LGL89_RS10385	COG4174	ABC transporter (Permease)
LGL89_RS10390	COG4239	(ABC) transporter, permease
LGL89_RS10395	COG4172	Belongs to the ABC transporter superfamily
LGL89_RS10405	COG2814	Major facilitator Superfamily
LGL89_RS10410	COG1187	pseudouridine synthase activity
LGL89_RS10415	COG1061	Type III restriction enzyme res subunit
LGL89_RS10430	COG3082	Protein of unknown function (DUF1414)
LGL89_RS10435	COG3083	sulfuric ester hydrolase activity
LGL89_RS10465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL89_RS10470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL89_RS10490	COG2223	nitrite transmembrane transporter activity
LGL89_RS10495	COG2198	Histidine kinase
LGL89_RS10495	COG0642	Histidine kinase
LGL89_RS10505	COG0784	Response regulator, receiver
LGL89_RS10505	COG2205	protein histidine kinase activity
LGL89_RS10515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL89_RS10520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL89_RS10530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL89_RS10540	COG4574	serine-type endopeptidase inhibitor activity
LGL89_RS10550	COG2246	polysaccharide biosynthetic process
LGL89_RS10570	COG0814	amino acid
LGL89_RS10595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL89_RS10600	COG0596	Alpha beta hydrolase
LGL89_RS10605	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL89_RS10610	COG1169	isochorismate synthase
LGL89_RS10615	COG4575	ribosome binding
LGL89_RS10630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL89_RS10635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL89_RS10645	COG0839	Belongs to the complex I subunit 6 family
LGL89_RS10650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL89_RS10655	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL89_RS10660	COG1034	ATP synthesis coupled electron transport
LGL89_RS10680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL89_RS10685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL89_RS10690	COG0583	DNA-binding transcription factor activity
LGL89_RS10695	COG0436	Aminotransferase
LGL89_RS10700	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL89_RS10705	COG0490	domain, Protein
LGL89_RS10705	COG0471	metal ion transport
LGL89_RS10715	COG3013	Belongs to the UPF0304 family
LGL89_RS10720	COG3092	negative regulation of chromosome organization
LGL89_RS10730	COG0857	belongs to the CobB CobQ family
LGL89_RS10730	COG0280	phosphate acetyltransferase
LGL89_RS10735	COG1609	Transcriptional regulator
LGL89_RS10750	COG3037	sugar-specific permease SgaT UlaA
LGL89_RS10755	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL89_RS10760	COG0622	Phosphoesterase
LGL89_RS10770	COG0625	glutathione transferase activity
LGL89_RS10775	COG1090	epimerase
LGL89_RS10785	COG4160	amino acid transport
LGL89_RS10790	COG4215	(ABC) transporter
LGL89_RS10805	COG0163	prenyltransferase activity
LGL89_RS10810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL89_RS10815	COG1286	toxin biosynthetic process
LGL89_RS10820	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL89_RS10825	COG0285	dihydrofolate synthase activity
LGL89_RS10835	COG0586	Pfam SNARE associated Golgi protein
LGL89_RS10845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL89_RS10870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL89_RS10875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL89_RS10905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL89_RS10920	COG3101	peptidyl-lysine hydroxylation
LGL89_RS10925	COG0730	response to heat
LGL89_RS10930	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL89_RS10940	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL89_RS10945	COG2840	Smr protein MutS2
LGL89_RS10950	COG2062	phosphohistidine phosphatase, SixA
LGL89_RS10955	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL89_RS10955	COG1024	Enoyl-CoA hydratase
LGL89_RS10960	COG0183	Belongs to the thiolase family
LGL89_RS10965	COG3691	Protein conserved in bacteria
LGL89_RS10980	COG4235	cytochrome complex assembly
LGL89_RS10980	COG3088	subunit of a heme lyase
LGL89_RS10985	COG4235	cytochrome complex assembly
LGL89_RS10985	COG3088	subunit of a heme lyase
LGL89_RS10990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL89_RS10995	COG1138	Cytochrome C-type biogenesis protein
LGL89_RS11000	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL89_RS11005	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL89_RS11010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL89_RS11015	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL89_RS11035	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL89_RS11040	COG2951	lytic endotransglycosylase activity
LGL89_RS11045	COG1598	PFAM Uncharacterised protein family UPF0150
LGL89_RS11055	COG3038	cytochrome b561
LGL89_RS11060	COG0436	Aminotransferase
LGL89_RS11070	COG3275	phosphorelay sensor kinase activity
LGL89_RS11075	COG3279	Response regulator of the LytR AlgR family
LGL89_RS11080	COG2223	nitrite transmembrane transporter activity
LGL89_RS11085	COG0837	glucose binding
LGL89_RS11105	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL89_RS11110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL89_RS11170	COG3530	Putative quorum-sensing-regulated virulence factor
LGL89_RS11175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL89_RS11185	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL89_RS11195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL89_RS11210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL89_RS11220	COG4208	sulfate ABC transporter
LGL89_RS11225	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL89_RS11230	COG4150	thiosulfate binding
LGL89_RS11240	COG1737	Transcriptional regulator
LGL89_RS11245	COG2731	YhcH YjgK YiaL family protein
LGL89_RS11260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL89_RS11265	COG2837	iron assimilation
LGL89_RS11275	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL89_RS11290	COG1671	Belongs to the UPF0178 family
LGL89_RS11295	COG0281	malic enzyme
LGL89_RS11295	COG0280	phosphate acetyltransferase
LGL89_RS11300	COG0494	nUDIX hydrolase
LGL89_RS11305	COG3005	denitrification pathway
LGL89_RS11310	COG3043	anaerobic respiration
LGL89_RS11315	COG0243	molybdopterin cofactor binding
LGL89_RS11320	COG3062	negative regulation of establishment of protein localization
LGL89_RS11325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL89_RS11325	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL89_RS11330	COG2197	response regulator
LGL89_RS11340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL89_RS11350	COG1605	Chorismate mutase
LGL89_RS11355	COG1393	Belongs to the ArsC family
LGL89_RS11360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL89_RS11365	COG1876	peptidase activity
LGL89_RS11375	COG0400	carboxylic ester hydrolase activity
LGL89_RS11395	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL89_RS11400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL89_RS11405	COG2716	regulation of RNA biosynthetic process
LGL89_RS11410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL89_RS11415	COG0628	permease
LGL89_RS11420	COG4783	chaperone-mediated protein folding
LGL89_RS11425	COG1393	Belongs to the ArsC family
LGL89_RS11430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL89_RS11435	COG2233	PERMEase
LGL89_RS11440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL89_RS11445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL89_RS11450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL89_RS11455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL89_RS11465	COG0581	inorganic phosphate transmembrane transporter activity
LGL89_RS11470	COG0573	inorganic phosphate transmembrane transporter activity
LGL89_RS11475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL89_RS11490	COG2239	Acts as a magnesium transporter
LGL89_RS11495	COG0443	Heat shock 70 kDa protein
LGL89_RS11505	COG3121	Chaperone
LGL89_RS11525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL89_RS11535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL89_RS11540	COG0477	Major facilitator Superfamily
LGL89_RS11545	COG2205	protein histidine kinase activity
LGL89_RS11550	COG0745	RESPONSE REGULATOR receiver
LGL89_RS11555	COG3422	double-strand break repair
LGL89_RS11560	COG0826	peptidase U32
LGL89_RS11565	COG1597	lipid kinase activity
LGL89_RS11580	COG0351	phosphomethylpyrimidine kinase
LGL89_RS11595	COG0519	Catalyzes the synthesis of GMP from XMP
LGL89_RS11595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL89_RS11600	COG0517	IMP dehydrogenase activity
LGL89_RS11600	COG0516	GMP reductase activity
LGL89_RS11605	COG1570	exodeoxyribonuclease VII activity
LGL89_RS11620	COG1645	bacterial-type flagellum-dependent swarming motility
LGL89_RS11630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL89_RS11635	COG2976	Protein conserved in bacteria
LGL89_RS11640	COG0124	histidyl-tRNA synthetase
LGL89_RS11660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL89_RS11675	COG4953	penicillin-binding protein 1C
LGL89_RS11680	COG2373	Large extracellular alpha-helical protein
LGL89_RS11695	COG2975	iron-sulfur cluster assembly
LGL89_RS11700	COG0633	Ferredoxin
LGL89_RS11705	COG0443	Heat shock 70 kDa protein
LGL89_RS11720	COG0822	iron-sulfur transferase activity
LGL89_RS11730	COG1959	2 iron, 2 sulfur cluster binding
LGL89_RS11735	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL89_RS11745	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL89_RS11750	COG3683	transport system, periplasmic component
LGL89_RS11755	COG3711	transcriptional antiterminator
LGL89_RS11760	COG2814	Major facilitator Superfamily
LGL89_RS11770	COG1017	nitric oxide dioxygenase activity
LGL89_RS11770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL89_RS11775	COG2188	Transcriptional regulator
LGL89_RS11785	COG3457	Alanine racemase
LGL89_RS11790	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL89_RS11805	COG0347	Belongs to the P(II) protein family
LGL89_RS11810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL89_RS11810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL89_RS11815	COG2204	response regulator
LGL89_RS11820	COG3170	Tfp pilus assembly protein FimV
LGL89_RS11825	COG2205	protein histidine kinase activity
LGL89_RS11840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL89_RS11850	COG0560	Phosphoserine phosphatase
LGL89_RS11855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL89_RS11855	COG1263	PTS System
LGL89_RS11865	COG1737	Transcriptional regulator
LGL89_RS11870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL89_RS11880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL89_RS11890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL89_RS11905	COG0481	GTPase activity
LGL89_RS11910	COG3086	response to oxidative stress
LGL89_RS11920	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL89_RS11930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL89_RS11940	COG0513	Belongs to the DEAD box helicase family
LGL89_RS11955	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL89_RS11965	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL89_RS11970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL89_RS11975	COG0497	DNA recombination
LGL89_RS11980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL89_RS11990	COG2867	negative regulation of translational initiation
LGL89_RS11995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL89_RS12030	COG2856	Zn peptidase
LGL89_RS12040	COG3596	GTP binding
LGL89_RS12045	COG2378	regulation of single-species biofilm formation
LGL89_RS12055	COG2378	regulation of single-species biofilm formation
LGL89_RS12070	COG2003	Belongs to the UPF0758 family
LGL89_RS12105	COG3121	Chaperone
LGL89_RS12110	COG3188	usher protein
LGL89_RS12135	COG0583	DNA-binding transcription factor activity
LGL89_RS12210	COG1069	ribulokinase activity
LGL89_RS12220	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL89_RS12225	COG1129	ABC transporter
LGL89_RS12245	COG1620	l-lactate permease
LGL89_RS12250	COG1304	FMN binding
LGL89_RS12255	COG0579	oxidoreductase
LGL89_RS12260	COG1278	Cold shock
LGL89_RS12290	COG1780	Probably involved in ribonucleotide reductase function
LGL89_RS12295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL89_RS12305	COG4175	Glycine betaine
LGL89_RS12310	COG4176	ABC-type proline glycine betaine transport system permease component
LGL89_RS12315	COG2113	Glycine betaine
LGL89_RS12325	COG2814	Major facilitator Superfamily
LGL89_RS12330	COG1846	Transcriptional regulator
LGL89_RS12340	COG1566	PFAM secretion protein HlyD family protein
LGL89_RS12345	COG2814	Major facilitator Superfamily
LGL89_RS12350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL89_RS12355	COG3118	belongs to the thioredoxin family
LGL89_RS12360	COG3148	PFAM DTW domain containing protein
LGL89_RS12365	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL89_RS12365	COG1042	CoA-binding domain protein
LGL89_RS12365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL89_RS12370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL89_RS12375	COG5544	Lipoprotein
LGL89_RS12400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL89_RS12410	COG2011	ABC-type metal ion transport system permease component
LGL89_RS12415	COG1464	Belongs to the NlpA lipoprotein family
LGL89_RS12425	COG1720	tRNA m6t6A37 methyltransferase activity
LGL89_RS12430	COG0442	prolyl-tRNA aminoacylation
LGL89_RS12435	COG3015	lipoprotein NlpE involved in copper resistance
LGL89_RS12445	COG4681	YaeQ
LGL89_RS12455	COG4568	rho-dependent transcription termination
LGL89_RS12470	COG0346	lactoylglutathione lyase activity
LGL89_RS12485	COG0825	malonyl-CoA metabolic process
LGL89_RS12490	COG0587	DNA-directed DNA polymerase activity
LGL89_RS12495	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL89_RS12515	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL89_RS12520	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL89_RS12530	COG0750	zinc metalloprotease
LGL89_RS12535	COG0575	Belongs to the CDS family
LGL89_RS12555	COG0528	UMP kinase activity
LGL89_RS12560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL89_RS12580	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL89_RS12585	COG2171	N-acyltransferase activity
LGL89_RS12600	COG0564	pseudouridine synthase activity
LGL89_RS12605	COG3098	single-species biofilm formation
LGL89_RS12620	COG1611	Belongs to the LOG family
LGL89_RS12630	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL89_RS12635	COG2363	Small membrane protein
LGL89_RS12640	COG0583	DNA-binding transcription factor activity
LGL89_RS12650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL89_RS12655	COG2166	iron-sulfur cluster assembly
LGL89_RS12660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL89_RS12665	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL89_RS12685	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL89_RS12690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL89_RS12690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL89_RS12695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL89_RS12700	COG1074	ATP-dependent DNA helicase activity
LGL89_RS12705	COG1025	Belongs to the peptidase M16 family
LGL89_RS12710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL89_RS12715	COG4967	type IV pilus modification protein PilV
LGL89_RS12740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL89_RS12745	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL89_RS12755	COG3066	DNA modification
LGL89_RS12760	COG0861	Integral membrane protein TerC family
LGL89_RS12765	COG0667	Aldo Keto reductase
LGL89_RS12770	COG0477	Major facilitator Superfamily
LGL89_RS12775	COG0318	PFAM AMP-dependent synthetase and ligase
LGL89_RS12775	COG0204	Acyl-transferase
LGL89_RS12780	COG1609	Transcriptional regulator
LGL89_RS12790	COG0583	DNA-binding transcription factor activity
LGL89_RS12795	COG0583	DNA-binding transcription factor activity
LGL89_RS12855	COG2165	general secretion pathway protein
LGL89_RS12865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL89_RS12895	COG1127	ABC transporter
LGL89_RS12900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL89_RS12965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL89_RS12975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL89_RS12980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL89_RS12985	COG4974	Belongs to the 'phage' integrase family
LGL89_RS12990	COG0716	FMN binding
LGL89_RS13000	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL89_RS13010	COG1272	protein, Hemolysin III
LGL89_RS13030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL89_RS13035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL89_RS13040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL89_RS13045	COG0006	proline dipeptidase activity
LGL89_RS13055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL89_RS13065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL89_RS13070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL89_RS13075	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL89_RS13100	COG0191	fructose-bisphosphate aldolase activity
LGL89_RS13105	COG0126	phosphoglycerate kinase activity
LGL89_RS13110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL89_RS13115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL89_RS13125	COG1166	arginine decarboxylase activity
LGL89_RS13130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL89_RS13145	COG0640	Transcriptional regulator
LGL89_RS13150	COG3091	SprT-like family
LGL89_RS13155	COG2356	endonuclease I
LGL89_RS13160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL89_RS13165	COG0189	ligase activity
LGL89_RS13170	COG1678	Uncharacterized ACR, COG1678
LGL89_RS13175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL89_RS13180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL89_RS13190	COG2805	Type II/IV secretion system protein
LGL89_RS13195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL89_RS13200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL89_RS13205	COG0762	integral membrane protein
LGL89_RS13210	COG1872	DUF167
LGL89_RS13215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL89_RS13220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL89_RS13235	COG3171	Protein conserved in bacteria
LGL89_RS13245	COG1194	a g-specific adenine glycosylase
LGL89_RS13250	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL89_RS13255	COG0741	lytic transglycosylase activity
LGL89_RS13265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL89_RS13450	COG2131	deaminase
LGL89_RS13610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL89_RS13670	COG3730	PTS system glucitol sorbitol-specific
LGL89_RS13675	COG3732	PTS system glucitol sorbitol-specific
LGL89_RS13680	COG3731	PTS system glucitol sorbitol-specific IIA component
LGL89_RS13685	COG1028	Short-chain dehydrogenase reductase Sdr
LGL89_RS13690	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL89_RS13695	COG1349	DNA-binding transcription factor activity
LGL89_RS13705	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL89_RS13710	COG1882	Formate acetyltransferase
LGL89_RS13715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL89_RS13720	COG0814	amino acid
LGL89_RS13735	COG1028	Short-chain dehydrogenase reductase Sdr
LGL89_RS13740	COG1535	isochorismatase
LGL89_RS13740	COG3433	isochorismatase activity
LGL89_RS13745	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL89_RS13750	COG1169	isochorismate synthase
LGL89_RS13755	COG4592	Periplasmic binding protein
LGL89_RS13765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL89_RS13770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL89_RS13775	COG1120	ATPase activity
LGL89_RS13785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL89_RS13790	COG3251	PFAM MbtH domain protein
LGL89_RS13800	COG4774	siderophore transport
LGL89_RS13805	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL89_RS13835	COG4964	Belongs to the GSP D family
LGL89_RS13880	COG0848	biopolymer transport protein
LGL89_RS13885	COG0811	peptide transport
LGL89_RS13890	COG0626	cystathionine gamma-synthase activity
LGL89_RS13895	COG0586	Pfam SNARE associated Golgi protein
LGL89_RS13900	COG2207	Transcriptional regulator
LGL89_RS13905	COG1979	alcohol dehydrogenase
LGL89_RS13910	COG0656	L-ascorbic acid biosynthetic process
LGL89_RS13920	COG2132	Multicopper oxidase
LGL89_RS13930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGL89_RS13935	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL89_RS13940	COG0583	DNA-binding transcription factor activity
LGL89_RS13945	COG0187	DNA topoisomerase II activity
LGL89_RS13950	COG3150	esterase
LGL89_RS13955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL89_RS13960	COG3151	Protein conserved in bacteria
LGL89_RS13965	COG0494	nUDIX hydrolase
LGL89_RS13970	COG1538	Outer membrane efflux protein
LGL89_RS13975	COG5463	Belongs to the UPF0441 family
LGL89_RS13980	COG0754	glutathionylspermidine amidase activity
LGL89_RS13985	COG3384	dioxygenase
LGL89_RS13990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL89_RS14000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL89_RS14000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL89_RS14010	COG3025	triphosphatase activity
LGL89_RS14015	COG4991	sh3 domain protein
LGL89_RS14020	COG0617	tRNA 3'-terminal CCA addition
LGL89_RS14025	COG1968	undecaprenyl-diphosphatase activity
LGL89_RS14030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL89_RS14035	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL89_RS14040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL89_RS14045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL89_RS14050	COG0358	DNA primase activity
LGL89_RS14080	COG2003	Belongs to the UPF0758 family
LGL89_RS14120	COG2378	regulation of single-species biofilm formation
LGL89_RS14130	COG3596	GTP binding
LGL89_RS14135	COG0210	DNA helicase
LGL89_RS14160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LGL89_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
LGL89_RS14210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL89_RS14255	COG3210	domain, Protein
LGL89_RS14260	COG2831	hemolysin activation secretion protein
LGL89_RS14265	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL89_RS14265	COG1902	pentaerythritol trinitrate reductase activity
LGL89_RS14280	COG1451	nucleotide metabolic process
LGL89_RS14285	COG0673	inositol 2-dehydrogenase activity
LGL89_RS14290	COG0861	Integral membrane protein TerC family
LGL89_RS14295	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL89_RS14305	COG2721	sulfolactate sulfo-lyase activity
LGL89_RS14320	COG2271	Major facilitator Superfamily
LGL89_RS14335	COG0586	Pfam SNARE associated Golgi protein
LGL89_RS14350	COG4575	ribosome binding
LGL89_RS14355	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL89_RS14365	COG2259	Doxx family
LGL89_RS14370	COG0583	DNA-binding transcription factor activity
LGL89_RS14375	COG1741	Belongs to the pirin family
LGL89_RS14390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL89_RS14405	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL89_RS14410	COG2823	Periplasmic or secreted lipoprotein
LGL89_RS14415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL89_RS14420	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL89_RS14425	COG0784	Response regulator, receiver
LGL89_RS14425	COG2198	Histidine kinase
LGL89_RS14425	COG5002	protein histidine kinase activity
LGL89_RS14435	COG1242	4 iron, 4 sulfur cluster binding
LGL89_RS14440	COG0070	glutamate synthase
LGL89_RS14440	COG0067	glutamate synthase
LGL89_RS14440	COG0069	glutamate synthase activity
LGL89_RS14445	COG0493	'glutamate synthase
LGL89_RS14455	COG2969	positive regulation of protein catabolic process
LGL89_RS14460	COG0625	glutathione transferase activity
LGL89_RS14465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL89_RS14470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL89_RS14475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL89_RS14480	COG3105	Protein conserved in bacteria
LGL89_RS14485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL89_RS14495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL89_RS14500	COG5007	Belongs to the BolA IbaG family
LGL89_RS14505	COG3113	response to antibiotic
LGL89_RS14510	COG2854	intermembrane phospholipid transfer
LGL89_RS14515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL89_RS14520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL89_RS14525	COG1127	ABC transporter
LGL89_RS14530	COG0530	calcium, potassium:sodium antiporter activity
LGL89_RS14535	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL89_RS14535	COG0517	IMP dehydrogenase activity
LGL89_RS14540	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL89_RS14545	COG3117	lipopolysaccharide transmembrane transporter activity
LGL89_RS14550	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL89_RS14555	COG1137	ATPase activity
LGL89_RS14560	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL89_RS14580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL89_RS14585	COG0540	Belongs to the ATCase OTCase family
LGL89_RS14590	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL89_RS14600	COG0366	Alpha amylase catalytic
LGL89_RS14605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL89_RS14605	COG1263	PTS System
LGL89_RS14615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL89_RS14625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL89_RS14630	COG3783	Cytochrome b(562)
LGL89_RS14635	COG0312	modulator of DNA gyrase
LGL89_RS14640	COG3028	Belongs to the UPF0307 family
LGL89_RS14645	COG2732	(Barnase) inhibitor
LGL89_RS14650	COG4290	ribonuclease
LGL89_RS14660	COG1289	transmembrane transporter activity
LGL89_RS14675	COG0583	DNA-binding transcription factor activity
LGL89_RS14680	COG0312	modulator of DNA gyrase
LGL89_RS14685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL89_RS14690	COG3164	Protein of unknown function
LGL89_RS14700	COG0424	maF-like protein
LGL89_RS14705	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL89_RS14710	COG1792	Involved in formation and maintenance of cell shape
LGL89_RS14715	COG1077	Cell shape determining protein MreB Mrl
LGL89_RS14720	COG2200	EAL domain
LGL89_RS14720	COG2199	diguanylate cyclase activity
LGL89_RS14725	COG0604	alcohol dehydrogenase
LGL89_RS14730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL89_RS14735	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL89_RS14745	COG0511	ligase activity, forming carbon-carbon bonds
LGL89_RS14750	COG0439	Biotin carboxylase
LGL89_RS14755	COG3924	membrane
LGL89_RS14760	COG4145	pantothenate transmembrane transporter activity
LGL89_RS14765	COG2264	protein methyltransferase activity
LGL89_RS14770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL89_RS14775	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL89_RS14785	COG1560	Kdo2-lipid A biosynthetic process
LGL89_RS14795	COG1346	cytolysis
LGL89_RS14800	COG1380	Effector of murein hydrolase LrgA
LGL89_RS14805	COG0583	DNA-binding transcription factor activity
LGL89_RS14810	COG0025	NhaP-type Na H and K H
LGL89_RS14815	COG2252	PERMEase
LGL89_RS14830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL89_RS14835	COG2315	Protein conserved in bacteria
LGL89_RS14840	COG1448	Aminotransferase
LGL89_RS14855	COG0604	alcohol dehydrogenase
LGL89_RS14865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL89_RS14870	COG0735	belongs to the Fur family
LGL89_RS14875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL89_RS14880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL89_RS14885	COG2937	Belongs to the GPAT DAPAT family
LGL89_RS14905	COG4580	involved in the transport of maltose and maltodextrins
LGL89_RS14920	COG2182	Extracellular solute-binding protein
LGL89_RS14925	COG1175	transmembrane transport
LGL89_RS14930	COG3833	ABC-type maltose transport systems, permease component
LGL89_RS14935	COG3223	Belongs to the PsiE family
LGL89_RS14945	COG0527	aspartate kinase activity
LGL89_RS14960	COG3328	transposase activity
LGL89_RS14985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGL89_RS15065	COG0583	DNA-binding transcription factor activity
LGL89_RS15100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL89_RS15145	COG0138	bifunctional purine biosynthesis protein purh
LGL89_RS15150	COG0151	Belongs to the GarS family
LGL89_RS15170	COG1515	deoxyribonuclease V activity
LGL89_RS15175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL89_RS15180	COG2816	NAD+ diphosphatase activity
LGL89_RS15185	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL89_RS15200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL89_RS15205	COG2104	thiamine diphosphate biosynthetic process
LGL89_RS15210	COG2022	thiamine diphosphate biosynthetic process
LGL89_RS15220	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL89_RS15225	COG0085	RNA polymerase activity
LGL89_RS15230	COG0222	ribosome binding
LGL89_RS15235	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL89_RS15245	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL89_RS15250	COG0250	Participates in transcription elongation, termination and antitermination
LGL89_RS15295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL89_RS15320	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL89_RS15325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL89_RS15330	COG1739	Uncharacterized protein family UPF0029
LGL89_RS15340	COG1024	Enoyl-CoA hydratase
LGL89_RS15340	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL89_RS15350	COG0543	2 iron, 2 sulfur cluster binding
LGL89_RS15365	COG0250	Participates in transcription elongation, termination and antitermination
LGL89_RS15380	COG0805	protein transport
LGL89_RS15385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL89_RS15390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL89_RS15395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL89_RS15400	COG3165	ubiquinone biosynthetic process from chorismate
LGL89_RS15405	COG2226	methyltransferase
LGL89_RS15410	COG1322	Protein conserved in bacteria
LGL89_RS15415	COG0586	Pfam SNARE associated Golgi protein
LGL89_RS15420	COG1966	Carbon starvation protein
LGL89_RS15435	COG0412	Dienelactone hydrolase
LGL89_RS15440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL89_RS15445	COG0583	DNA-binding transcription factor activity
LGL89_RS15450	COG0697	spore germination
LGL89_RS15460	COG0584	glycerophosphoryl diester phosphodiesterase
LGL89_RS15470	COG0395	ABC-type sugar transport system, permease component
LGL89_RS15475	COG1175	transmembrane transport
LGL89_RS15480	COG1653	transport
LGL89_RS15515	COG0410	ABC transporter
LGL89_RS15525	COG4177	L-phenylalanine transmembrane transporter activity
LGL89_RS15545	COG1929	Belongs to the glycerate kinase type-1 family
LGL89_RS15550	COG2610	gluconate transmembrane transporter activity
LGL89_RS15555	COG3835	regulator
LGL89_RS15565	COG2177	Part of the ABC transporter FtsEX involved in
LGL89_RS15570	COG2884	Cell division ATP-binding protein ftsE
LGL89_RS15575	COG0552	protein localization to endoplasmic reticulum
LGL89_RS15575	COG0552	protein localization to endoplasmic reticulum
LGL89_RS15580	COG0742	ribosomal rna small subunit methyltransferase
LGL89_RS15585	COG3776	membrane
LGL89_RS15600	COG3714	YhhN family
LGL89_RS15615	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL89_RS15625	COG0247	lactate metabolic process
LGL89_RS15635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL89_RS15645	COG2271	Major facilitator Superfamily
LGL89_RS15650	COG0584	glycerophosphoryl diester phosphodiesterase
LGL89_RS15655	COG0561	phosphatase activity
LGL89_RS15660	COG2267	carboxylic ester hydrolase activity
LGL89_RS15665	COG1280	lysine exporter protein (LysE YggA)
LGL89_RS15670	COG0514	ATP-dependent DNA helicase (RecQ)
LGL89_RS15675	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL89_RS15680	COG2050	protein possibly involved in aromatic compounds catabolism
LGL89_RS15700	COG5564	TIM-barrel signal transduction protein
LGL89_RS15705	COG5441	Belongs to the UPF0261 family
LGL89_RS15715	COG0210	DNA helicase
LGL89_RS15720	COG1011	Hydrolase
LGL89_RS15725	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL89_RS15730	COG3159	Protein conserved in bacteria
LGL89_RS15735	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL89_RS15740	COG5567	small periplasmic lipoprotein
LGL89_RS15750	COG3072	Adenylate cyclase
LGL89_RS15755	COG0181	hydroxymethylbilane synthase activity
LGL89_RS15760	COG1587	Uroporphyrinogen-III synthase
LGL89_RS15765	COG2959	enzyme of heme biosynthesis
LGL89_RS15770	COG3071	HemY protein
LGL89_RS15820	COG2244	polysaccharide biosynthetic process
LGL89_RS15825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL89_RS15830	COG0456	acetyltransferase
LGL89_RS15835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL89_RS15840	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL89_RS15845	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL89_RS15850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL89_RS15855	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL89_RS15860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL89_RS15865	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL89_RS15870	COG3118	belongs to the thioredoxin family
LGL89_RS15880	COG0248	Ppx GppA phosphatase
LGL89_RS15890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL89_RS15905	COG3397	chitin binding
LGL89_RS15915	COG0129	dihydroxy-acid dehydratase activity
LGL89_RS15925	COG3978	acetolactate synthase activity
LGL89_RS15945	COG3085	chromosome segregation
LGL89_RS15950	COG0583	DNA-binding transcription factor activity
LGL89_RS16005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL89_RS16020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL89_RS16030	COG0678	peroxiredoxin activity
LGL89_RS16030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL89_RS16035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL89_RS16070	COG1629	transport
LGL89_RS16075	COG0165	Argininosuccinate lyase
LGL89_RS16080	COG0137	argininosuccinate synthase activity
LGL89_RS16085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL89_RS16135	COG0460	homoserine dehydrogenase
LGL89_RS16135	COG0527	aspartate kinase activity
LGL89_RS16140	COG0626	cystathionine gamma-synthase activity
LGL89_RS16145	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL89_RS16155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL89_RS16160	COG1609	Transcriptional regulator
LGL89_RS16165	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL89_RS16170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL89_RS16175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL89_RS16180	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL89_RS16185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL89_RS16190	COG3074	FtsZ-dependent cytokinesis
LGL89_RS16195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL89_RS16200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL89_RS16205	COG1494	fructose-1,6-bisphosphatase
LGL89_RS16210	COG2814	Major facilitator Superfamily
LGL89_RS16220	COG3152	Membrane
LGL89_RS16235	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL89_RS16245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL89_RS16250	COG3678	ATP-independent chaperone mediated protein folding
LGL89_RS16255	COG0745	RESPONSE REGULATOR receiver
LGL89_RS16260	COG2205	protein histidine kinase activity
LGL89_RS16265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL89_RS16270	COG1045	serine acetyltransferase
LGL89_RS16275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL89_RS16280	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL89_RS16285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL89_RS16290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL89_RS16295	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL89_RS16300	COG4942	peptidase
LGL89_RS16305	COG2861	carbohydrate metabolic process
LGL89_RS16320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL89_RS16325	COG0859	PFAM glycosyl transferase family 9
LGL89_RS16330	COG0859	PFAM glycosyl transferase family 9
LGL89_RS16335	COG1519	Transferase
LGL89_RS16355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL89_RS16360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL89_RS16365	COG2003	Belongs to the UPF0758 family
LGL89_RS16370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL89_RS16375	COG0756	dUTP diphosphatase activity
LGL89_RS16380	COG1309	transcriptional regulator
LGL89_RS16385	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL89_RS16390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL89_RS16395	COG1561	YicC-like family, N-terminal region
LGL89_RS16410	COG5001	Diguanylate cyclase
LGL89_RS16415	COG1024	Enoyl-CoA hydratase
LGL89_RS16420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL89_RS16435	COG2860	membrane
LGL89_RS16440	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL89_RS16450	COG1758	RNA polymerase activity
LGL89_RS16455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL89_RS16460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL89_RS16465	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL89_RS16470	COG0786	glutamate:sodium symporter activity
LGL89_RS16475	COG2233	PERMEase
LGL89_RS16480	COG2982	Protein involved in outer membrane biogenesis
LGL89_RS16485	COG0456	acetyltransferase
LGL89_RS16500	COG1011	Hydrolase
LGL89_RS16515	COG3852	Histidine kinase
LGL89_RS16525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL89_RS16535	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL89_RS16545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL89_RS16545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL89_RS16550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL89_RS16555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL89_RS16560	COG3084	Protein conserved in bacteria
LGL89_RS16570	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL89_RS16595	COG2186	Transcriptional regulator
LGL89_RS16600	COG1609	Transcriptional regulator
LGL89_RS16605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL89_RS16615	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL89_RS16620	COG1129	ABC transporter
LGL89_RS16625	COG1869	D-ribose catabolic process
LGL89_RS16630	COG3158	transport of potassium into the cell
LGL89_RS16635	COG0714	Associated with various cellular activities
LGL89_RS16640	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL89_RS16650	COG2502	aspartate--ammonia ligase
LGL89_RS16655	COG1522	sequence-specific DNA binding
LGL89_RS16660	COG0716	FMN binding
LGL89_RS16665	COG0445	tRNA wobble uridine modification
LGL89_RS16670	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL89_RS16675	COG3312	ion transport
LGL89_RS16680	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL89_RS16690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL89_RS16700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL89_RS16705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL89_RS16715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL89_RS16730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL89_RS16735	COG0573	inorganic phosphate transmembrane transporter activity
LGL89_RS16740	COG0581	inorganic phosphate transmembrane transporter activity
LGL89_RS16750	COG0704	Plays a role in the regulation of phosphate uptake
LGL89_RS16755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL89_RS16760	COG0765	amino acid transport
LGL89_RS16765	COG0765	amino acid transport
LGL89_RS16770	COG2252	PERMEase
LGL89_RS16775	COG0840	transmembrane signaling receptor activity
LGL89_RS16785	COG3121	Chaperone
LGL89_RS16800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL89_RS16805	COG0706	membrane insertase activity
LGL89_RS16815	COG0594	ribonuclease P activity
LGL89_RS16820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGL89_RS16835	COG2194	sulfuric ester hydrolase activity