locus-tag	class	description
LGL91_RS00010	COG0592	DNA-directed DNA polymerase activity
LGL91_RS00020	COG0187	DNA topoisomerase II activity
LGL91_RS00025	COG0561	phosphatase activity
LGL91_RS00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL91_RS00035	COG5645	(Lipo)protein
LGL91_RS00050	COG0569	domain protein
LGL91_RS00050	COG2985	domain, Protein
LGL91_RS00055	COG3977	Valine--pyruvate aminotransferase
LGL91_RS00060	COG2885	chlorophyll binding
LGL91_RS00085	COG2818	Glycosylase
LGL91_RS00135	COG2213	PTS system mannitol-specific
LGL91_RS00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_RS00145	COG3722	fumarate hydratase activity
LGL91_RS00155	COG2258	MOSC domain
LGL91_RS00160	COG0840	transmembrane signaling receptor activity
LGL91_RS00165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL91_RS00180	COG0437	4 iron, 4 sulfur cluster binding
LGL91_RS00185	COG2864	formate dehydrogenase
LGL91_RS00195	COG1921	L-seryl-tRNASec selenium transferase activity
LGL91_RS00200	COG3276	selenocysteine insertion sequence binding
LGL91_RS00205	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL91_RS00215	COG3274	enterobacterial common antigen metabolic process
LGL91_RS00225	COG0582	viral genome integration into host DNA
LGL91_RS00260	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL91_RS00265	COG2986	histidine ammonia-lyase
LGL91_RS00285	COG2194	sulfuric ester hydrolase activity
LGL91_RS00290	COG2197	response regulator
LGL91_RS00295	COG3851	Histidine kinase
LGL91_RS00300	COG2271	Major facilitator Superfamily
LGL91_RS00310	COG0747	negative chemotaxis
LGL91_RS00315	COG0601	transmembrane transport
LGL91_RS00320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL91_RS00325	COG0444	Belongs to the ABC transporter superfamily
LGL91_RS00330	COG4608	Belongs to the ABC transporter superfamily
LGL91_RS00335	COG2194	sulfuric ester hydrolase activity
LGL91_RS00360	COG1215	transferase activity, transferring glycosyl groups
LGL91_RS00365	COG1215	transferase activity, transferring glycosyl groups
LGL91_RS00370	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL91_RS00375	COG0457	Tetratricopeptide repeat
LGL91_RS00375	COG3118	belongs to the thioredoxin family
LGL91_RS00380	COG2199	diguanylate cyclase activity
LGL91_RS00380	COG2200	EAL domain
LGL91_RS00385	COG1301	dicarboxylic acid transport
LGL91_RS00390	COG0612	Peptidase, M16
LGL91_RS00395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL91_RS00400	COG1942	4-Oxalocrotonate Tautomerase
LGL91_RS00405	COG2200	EAL domain
LGL91_RS00415	COG1295	ribonuclease BN
LGL91_RS00425	COG1301	dicarboxylic acid transport
LGL91_RS00430	COG0626	cystathionine gamma-synthase activity
LGL91_RS00440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL91_RS00445	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL91_RS00450	COG0339	signal peptide processing
LGL91_RS00455	COG0742	ribosomal rna small subunit methyltransferase
LGL91_RS00465	COG0589	response to stress
LGL91_RS00475	COG0306	phosphate transporter
LGL91_RS00480	COG2081	HI0933 family
LGL91_RS00490	COG1247	-acetyltransferase
LGL91_RS00495	COG1741	Belongs to the pirin family
LGL91_RS00500	COG1609	Transcriptional regulator
LGL91_RS00505	COG2610	gluconate transmembrane transporter activity
LGL91_RS00510	COG3265	gluconokinase activity
LGL91_RS00515	COG2095	MarC family integral membrane protein
LGL91_RS00520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL91_RS00525	COG3275	phosphorelay sensor kinase activity
LGL91_RS00530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL91_RS00535	COG1523	belongs to the glycosyl hydrolase 13 family
LGL91_RS00540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL91_RS00545	COG0297	glycogen (starch) synthase activity
LGL91_RS00550	COG0058	SHG alpha-glucan phosphorylase activity
LGL91_RS00555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL91_RS00560	COG1349	DNA-binding transcription factor activity
LGL91_RS00565	COG0705	Rhomboid family
LGL91_RS00575	COG2909	trisaccharide binding
LGL91_RS00580	COG0058	SHG alpha-glucan phosphorylase activity
LGL91_RS00585	COG1640	4-alpha-glucanotransferase
LGL91_RS00595	COG1040	competence protein
LGL91_RS00600	COG0596	Alpha beta hydrolase
LGL91_RS00620	COG1918	ferrous iron import across plasma membrane
LGL91_RS00625	COG2183	response to ionizing radiation
LGL91_RS00650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL91_RS00665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL91_RS00675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL91_RS00680	COG1011	Hydrolase
LGL91_RS00690	COG0494	nUDIX hydrolase
LGL91_RS00695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL91_RS00720	COG4796	Type ii and iii secretion system protein
LGL91_RS00725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL91_RS00745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL91_RS00755	COG0180	Tryptophanyl-tRNA synthetase
LGL91_RS00775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL91_RS00780	COG0402	S-adenosylhomocysteine deaminase activity
LGL91_RS00785	COG0738	Major facilitator superfamily
LGL91_RS00800	COG1609	Transcriptional regulator
LGL91_RS00805	COG1486	melibiose metabolic process
LGL91_RS00810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL91_RS00825	COG1289	transmembrane transporter activity
LGL91_RS00830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL91_RS00835	COG1765	OsmC-like protein
LGL91_RS00860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL91_RS00865	COG3954	Phosphoribulokinase
LGL91_RS00875	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL91_RS00885	COG0859	PFAM glycosyl transferase family 9
LGL91_RS00890	COG1216	Glycosyl transferase, family 2
LGL91_RS00895	COG0488	(ABC) transporter
LGL91_RS00900	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL91_RS00910	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL91_RS00915	COG1047	Peptidyl-prolyl cis-trans
LGL91_RS00925	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL91_RS00930	COG2964	Protein conserved in bacteria
LGL91_RS00940	COG2923	Belongs to the DsrF TusC family
LGL91_RS00945	COG2168	tRNA wobble position uridine thiolation
LGL91_RS00950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL91_RS00955	COG0049	tRNA binding
LGL91_RS00965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL91_RS00980	COG0051	transcription antitermination factor activity, RNA binding
LGL91_RS00985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL91_RS00995	COG0089	rRNA binding
LGL91_RS01000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL91_RS01005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL91_RS01010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL91_RS01020	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL91_RS01025	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL91_RS01030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL91_RS01035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL91_RS01045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL91_RS01070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL91_RS01075	COG1841	ribosomal large subunit assembly
LGL91_RS01080	COG0200	Binds to the 23S rRNA
LGL91_RS01085	COG0201	protein transport
LGL91_RS01090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL91_RS01095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL91_RS01105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL91_RS01115	COG0203	ribosomal protein L17
LGL91_RS01120	COG0789	Transcriptional regulator
LGL91_RS01125	COG3036	rescue of stalled ribosome
LGL91_RS01130	COG1970	mechanosensitive ion channel activity
LGL91_RS01140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL91_RS01140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL91_RS01145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL91_RS01150	COG0242	peptide deformylase activity
LGL91_RS01155	COG0758	DNA mediated transformation
LGL91_RS01160	COG2922	Belongs to the Smg family
LGL91_RS01165	COG0551	DNA topoisomerase type I activity
LGL91_RS01170	COG0009	L-threonylcarbamoyladenylate synthase
LGL91_RS01180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL91_RS01205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL91_RS01250	COG0250	Participates in transcription elongation, termination and antitermination
LGL91_RS01255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL91_RS01265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL91_RS01270	COG0222	ribosome binding
LGL91_RS01275	COG0085	RNA polymerase activity
LGL91_RS01280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL91_RS01290	COG2022	thiamine diphosphate biosynthetic process
LGL91_RS01295	COG2104	thiamine diphosphate biosynthetic process
LGL91_RS01300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL91_RS01315	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL91_RS01320	COG2816	NAD+ diphosphatase activity
LGL91_RS01325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL91_RS01330	COG1515	deoxyribonuclease V activity
LGL91_RS01350	COG0151	Belongs to the GarS family
LGL91_RS01355	COG0138	bifunctional purine biosynthesis protein purh
LGL91_RS01390	COG3162	membrane
LGL91_RS01395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL91_RS01400	COG1301	dicarboxylic acid transport
LGL91_RS01410	COG1309	transcriptional regulator
LGL91_RS01415	COG4232	protein-disulfide reductase activity
LGL91_RS01425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL91_RS01455	COG1509	lysine 2,3-aminomutase activity
LGL91_RS01485	COG3188	usher protein
LGL91_RS01505	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL91_RS01510	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL91_RS01515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL91_RS01520	COG1053	succinate dehydrogenase
LGL91_RS01525	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL91_RS01530	COG3264	Mechanosensitive ion channel
LGL91_RS01530	COG1511	domain protein
LGL91_RS01535	COG0688	phosphatidylethanolamine metabolic process
LGL91_RS01540	COG1162	GTPase activity
LGL91_RS01545	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL91_RS01565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL91_RS01570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL91_RS01570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL91_RS01575	COG0802	atpase or kinase
LGL91_RS01580	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL91_RS01590	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL91_RS01600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL91_RS01605	COG0330	HflC and HflK could
LGL91_RS01610	COG0330	HflC and HflK could
LGL91_RS01615	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL91_RS01620	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL91_RS01625	COG1959	2 iron, 2 sulfur cluster binding
LGL91_RS01630	COG0557	exoribonuclease II activity
LGL91_RS01635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL91_RS01655	COG3121	Chaperone
LGL91_RS01660	COG3188	usher protein
LGL91_RS01680	COG1073	alpha beta
LGL91_RS01690	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL91_RS01695	COG2965	DNA replication, synthesis of RNA primer
LGL91_RS01700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL91_RS01705	COG0359	binds to the 23S rRNA
LGL91_RS01710	COG3061	Opacity-associated protein A
LGL91_RS01715	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL91_RS01725	COG0737	Belongs to the 5'-nucleotidase family
LGL91_RS01730	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL91_RS01735	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL91_RS01745	COG1253	flavin adenine dinucleotide binding
LGL91_RS01750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL91_RS01755	COG0729	surface antigen
LGL91_RS01760	COG2911	Protein conserved in bacteria
LGL91_RS01765	COG2105	PFAM AIG2 family protein
LGL91_RS01770	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL91_RS01780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL91_RS01795	COG3423	Transcriptional regulator
LGL91_RS01810	COG0142	geranyltranstransferase activity
LGL91_RS01825	COG0697	spore germination
LGL91_RS01830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL91_RS01835	COG0642	Histidine kinase
LGL91_RS01840	COG0745	RESPONSE REGULATOR receiver
LGL91_RS01845	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL91_RS01855	COG1534	Rna-binding protein
LGL91_RS01860	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL91_RS01870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL91_RS01875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL91_RS01880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL91_RS01900	COG0195	Participates in both transcription termination and antitermination
LGL91_RS01910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL91_RS01925	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL91_RS01935	COG0513	Belongs to the DEAD box helicase family
LGL91_RS01940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL91_RS01945	COG0814	amino acid
LGL91_RS01955	COG0826	peptidase U32
LGL91_RS01960	COG0826	peptidase U32
LGL91_RS01965	COG3154	lipid carrier protein
LGL91_RS01970	COG3153	acetyltransferase
LGL91_RS01975	COG2827	Endonuclease containing a URI domain
LGL91_RS01980	COG0531	amino acid
LGL91_RS01985	COG1982	Orn Lys Arg decarboxylase major
LGL91_RS01995	COG3787	Belongs to the UPF0306 family
LGL91_RS02000	COG0702	epimerase
LGL91_RS02005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL91_RS02010	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL91_RS02015	COG3454	Phosphonate metabolism
LGL91_RS02020	COG4778	phosphonate C-P lyase system protein PhnL
LGL91_RS02025	COG4107	phosphonate C-P lyase system protein PhnK
LGL91_RS02030	COG3627	carbon phosphorus lyase activity
LGL91_RS02035	COG3626	phosphonate metabolism
LGL91_RS02040	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL91_RS02045	COG3624	Phosphonate C-P lyase system protein PhnG
LGL91_RS02065	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL91_RS02080	COG2927	DNA polymerase III (CHI subunit)
LGL91_RS02085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL91_RS02090	COG0795	lipopolysaccharide-transporting ATPase activity
LGL91_RS02095	COG0795	lipopolysaccharide-transporting ATPase activity
LGL91_RS02120	COG3077	Addiction module antitoxin, RelB DinJ family
LGL91_RS02210	COG5492	domain, Protein
LGL91_RS02230	COG3119	arylsulfatase activity
LGL91_RS02235	COG1349	DNA-binding transcription factor activity
LGL91_RS02245	COG2222	sugar isomerase
LGL91_RS02250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_RS02255	COG3715	PTS system
LGL91_RS02260	COG3716	PTS system mannose fructose sorbose family IID component
LGL91_RS02270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL91_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_RS02290	COG0641	radical SAM
LGL91_RS02295	COG3119	arylsulfatase activity
LGL91_RS02320	COG0859	PFAM glycosyl transferase family 9
LGL91_RS02335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_RS02340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL91_RS02350	COG2376	Dihydroxyacetone kinase
LGL91_RS02355	COG1461	Dihydroxyacetone kinase
LGL91_RS02360	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL91_RS02360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_RS02360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL91_RS02400	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL91_RS02415	COG2823	Periplasmic or secreted lipoprotein
LGL91_RS02425	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL91_RS02430	COG0084	hydrolase, TatD family'
LGL91_RS02435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL91_RS02450	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL91_RS02460	COG3726	membrane protein affecting hemolysin expression
LGL91_RS02465	COG0560	Phosphoserine phosphatase
LGL91_RS02480	COG0488	(ABC) transporter
LGL91_RS02505	COG0741	lytic transglycosylase activity
LGL91_RS02510	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL91_RS02515	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL91_RS02520	COG0406	alpha-ribazole phosphatase activity
LGL91_RS02525	COG3708	Transcriptional regulator
LGL91_RS02525	COG2207	Transcriptional regulator
LGL91_RS02530	COG3045	CreA protein
LGL91_RS02535	COG0745	RESPONSE REGULATOR receiver
LGL91_RS02570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL91_RS02575	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL91_RS02580	COG0477	Major facilitator Superfamily
LGL91_RS02590	COG1584	GPR1 FUN34 yaaH family protein
LGL91_RS02595	COG0443	Heat shock 70 kDa protein
LGL91_RS02605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL91_RS02610	COG0583	DNA-binding transcription factor activity
LGL91_RS02620	COG0196	riboflavin kinase activity
LGL91_RS02630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL91_RS02635	COG1047	Peptidyl-prolyl cis-trans
LGL91_RS02640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL91_RS02655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL91_RS02665	COG2966	Psort location CytoplasmicMembrane, score
LGL91_RS02690	COG2967	ApaG domain
LGL91_RS02695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL91_RS02700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL91_RS02710	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL91_RS02720	COG0564	pseudouridine synthase activity
LGL91_RS02725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL91_RS02730	COG0417	DNA replication proofreading
LGL91_RS02735	COG0586	Pfam SNARE associated Golgi protein
LGL91_RS02745	COG1178	ABC-type Fe3 transport system permease component
LGL91_RS02750	COG4143	(ABC) transporter
LGL91_RS02765	COG2814	Major facilitator Superfamily
LGL91_RS02775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL91_RS02780	COG0473	3-isopropylmalate dehydrogenase activity
LGL91_RS02795	COG1022	Amp-dependent synthetase and ligase
LGL91_RS02800	COG0028	Belongs to the TPP enzyme family
LGL91_RS02825	COG0275	rRNA processing
LGL91_RS02830	COG3116	cell division
LGL91_RS02835	COG0768	penicillin binding
LGL91_RS02840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL91_RS02845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL91_RS02860	COG0772	Belongs to the SEDS family
LGL91_RS02865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL91_RS02870	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL91_RS02885	COG0849	cell division
LGL91_RS02890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL91_RS02915	COG0494	nUDIX hydrolase
LGL91_RS02935	COG0516	GMP reductase activity
LGL91_RS02940	COG1459	type II secretion system
LGL91_RS02945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL91_RS02950	COG4969	Belongs to the N-Me-Phe pilin family
LGL91_RS02965	COG3725	Membrane protein required for beta-lactamase induction
LGL91_RS02980	COG4932	domain protein
LGL91_RS02980	COG1388	LysM domain
LGL91_RS02980	COG2373	Large extracellular alpha-helical protein
LGL91_RS02985	COG1113	amino acid transport
LGL91_RS02990	COG2186	Transcriptional regulator
LGL91_RS02995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL91_RS03000	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL91_RS03005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL91_RS03015	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL91_RS03020	COG3112	Uncharacterised protein family (UPF0231)
LGL91_RS03035	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL91_RS03045	COG2132	Multicopper oxidase
LGL91_RS03055	COG0288	reversible hydration of carbon dioxide
LGL91_RS03060	COG1131	(ABC) transporter
LGL91_RS03065	COG0842	Transport permease protein
LGL91_RS03070	COG0726	polysaccharide deacetylase
LGL91_RS03075	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL91_RS03080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL91_RS03085	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL91_RS03090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL91_RS03095	COG0617	tRNA 3'-terminal CCA addition
LGL91_RS03110	COG1489	DNA binding
LGL91_RS03115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL91_RS03125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL91_RS03130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL91_RS03140	COG0316	Belongs to the HesB IscA family
LGL91_RS03145	COG2860	membrane
LGL91_RS03155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL91_RS03160	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL91_RS03165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL91_RS03175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL91_RS03180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL91_RS03185	COG3956	TIGRFAM MazG family protein
LGL91_RS03190	COG0504	CTP synthase activity
LGL91_RS03200	COG0602	queuosine metabolic process
LGL91_RS03205	COG0720	synthase
LGL91_RS03210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL91_RS03220	COG0175	sulfate reduction
LGL91_RS03235	COG2234	aminopeptidase activity
LGL91_RS03240	COG1648	precorrin-2 dehydrogenase activity
LGL91_RS03240	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL91_RS03245	COG0175	sulfate reduction
LGL91_RS03250	COG2895	sulfate adenylyltransferase (ATP) activity
LGL91_RS03255	COG0529	Catalyzes the synthesis of activated sulfate
LGL91_RS03265	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL91_RS03275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL91_RS03280	COG0585	pseudouridine synthase activity
LGL91_RS03285	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL91_RS03295	COG4942	peptidase
LGL91_RS03295	COG1388	LysM domain
LGL91_RS03300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL91_RS03305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL91_RS03315	COG0784	Response regulator, receiver
LGL91_RS03315	COG2205	protein histidine kinase activity
LGL91_RS03335	COG0741	lytic transglycosylase activity
LGL91_RS03455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL91_RS03475	COG3397	chitin binding
LGL91_RS03485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL91_RS03530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL91_RS03540	COG3031	protein transport across the cell outer membrane
LGL91_RS03570	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL91_RS03570	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL91_RS03585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL91_RS03590	COG2137	regulation of response to DNA damage stimulus
LGL91_RS03595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL91_RS03600	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL91_RS03635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL91_RS03640	COG1238	metal cluster binding
LGL91_RS03645	COG2918	glutathione biosynthetic process
LGL91_RS03650	COG1854	S-ribosylhomocysteine lyase activity
LGL91_RS03655	COG4536	flavin adenine dinucleotide binding
LGL91_RS03660	COG4137	Cytochrome C assembly protein
LGL91_RS03665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL91_RS03675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL91_RS03680	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL91_RS03685	COG0335	large ribosomal subunit rRNA binding
LGL91_RS03690	COG3137	Salt-induced outer membrane protein
LGL91_RS03695	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL91_RS03700	COG3279	Response regulator of the LytR AlgR family
LGL91_RS03705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL91_RS03710	COG0287	Prephenate dehydrogenase
LGL91_RS03710	COG1605	Chorismate mutase
LGL91_RS03715	COG1605	Chorismate mutase
LGL91_RS03715	COG0077	Prephenate dehydratase
LGL91_RS03720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL91_RS03725	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL91_RS03730	COG0564	pseudouridine synthase activity
LGL91_RS03735	COG1496	oxidoreductase activity
LGL91_RS03740	COG0542	response to heat
LGL91_RS03770	COG3021	interspecies interaction between organisms
LGL91_RS03775	COG1388	LysM domain
LGL91_RS03775	COG0741	lytic transglycosylase activity
LGL91_RS03785	COG2226	methyltransferase
LGL91_RS03795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL91_RS03805	COG1960	acyl-CoA dehydrogenase activity
LGL91_RS03810	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL91_RS03815	COG0121	glutamine amidotransferase
LGL91_RS03820	COG3034	peptidoglycan biosynthetic process
LGL91_RS03830	COG1805	sodium ion transport
LGL91_RS03835	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL91_RS03840	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL91_RS03845	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL91_RS03855	COG1477	protein flavinylation
LGL91_RS03860	COG2991	Protein conserved in bacteria
LGL91_RS03880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL91_RS03885	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL91_RS03890	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL91_RS03895	COG1073	alpha beta
LGL91_RS03910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL91_RS03945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL91_RS03965	COG4126	flavin adenine dinucleotide binding
LGL91_RS03975	COG2974	May be involved in recombination
LGL91_RS03980	COG1940	carbohydrate kinase activity
LGL91_RS03985	COG0419	ATPase involved in DNA repair
LGL91_RS03990	COG0420	3'-5' exonuclease activity
LGL91_RS03995	COG0745	RESPONSE REGULATOR receiver
LGL91_RS04000	COG5002	protein histidine kinase activity
LGL91_RS04010	COG1114	Component of the transport system for branched-chain amino acids
LGL91_RS04015	COG1113	amino acid transport
LGL91_RS04020	COG0366	Alpha amylase catalytic
LGL91_RS04025	COG0300	oxidoreductase activity
LGL91_RS04030	COG0450	alkyl hydroperoxide reductase
LGL91_RS04035	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL91_RS04050	COG1862	Preprotein translocase
LGL91_RS04055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL91_RS04060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL91_RS04065	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL91_RS04070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL91_RS04070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL91_RS04075	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL91_RS04085	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL91_RS04090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL91_RS04095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL91_RS04100	COG0142	geranyltranstransferase activity
LGL91_RS04135	COG0693	protein deglycase activity
LGL91_RS04140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL91_RS04145	COG1666	GTP binding
LGL91_RS04150	COG2814	Major facilitator Superfamily
LGL91_RS04160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL91_RS04165	COG1845	cytochrome c oxidase, subunit III
LGL91_RS04170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL91_RS04175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL91_RS04185	COG2223	nitrite transmembrane transporter activity
LGL91_RS04190	COG3056	Lipoprotein
LGL91_RS04195	COG0271	Belongs to the BolA IbaG family
LGL91_RS04205	COG0740	serine-type endopeptidase activity
LGL91_RS04210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL91_RS04215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL91_RS04220	COG0776	regulation of translation
LGL91_RS04225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL91_RS04230	COG1555	photosystem II stabilization
LGL91_RS04235	COG0824	Thioesterase
LGL91_RS04240	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL91_RS04245	COG4533	DNA binding
LGL91_RS04260	COG1522	sequence-specific DNA binding
LGL91_RS04265	COG1132	(ABC) transporter
LGL91_RS04270	COG1132	(ABC) transporter
LGL91_RS04275	COG0347	Belongs to the P(II) protein family
LGL91_RS04280	COG0004	ammonium transporteR
LGL91_RS04285	COG1946	Acyl-CoA thioesterase
LGL91_RS04290	COG3695	enzyme binding
LGL91_RS04315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL91_RS04320	COG0254	rRNA binding
LGL91_RS04325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL91_RS04330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_RS04335	COG1309	transcriptional regulator
LGL91_RS04340	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL91_RS04345	COG3264	Mechanosensitive ion channel
LGL91_RS04345	COG1196	nuclear chromosome segregation
LGL91_RS04360	COG2832	Protein of unknown function (DUF454)
LGL91_RS04365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL91_RS04405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL91_RS04410	COG0326	Molecular chaperone. Has ATPase activity
LGL91_RS04420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LGL91_RS04425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL91_RS04425	COG0543	2 iron, 2 sulfur cluster binding
LGL91_RS04445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_RS04490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_RS04495	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL91_RS04505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL91_RS04510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL91_RS04510	COG4651	solute:proton antiporter activity
LGL91_RS04515	COG0737	Belongs to the 5'-nucleotidase family
LGL91_RS04520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL91_RS04525	COG3735	TraB family
LGL91_RS04530	COG2217	Heavy metal translocating P-type atpase
LGL91_RS04535	COG0789	Transcriptional regulator
LGL91_RS04540	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL91_RS04545	COG0330	HflC and HflK could
LGL91_RS04550	COG3118	belongs to the thioredoxin family
LGL91_RS04555	COG0300	oxidoreductase activity
LGL91_RS04560	COG2755	lipolytic protein G-D-S-L family
LGL91_RS04565	COG4181	ATPase activity
LGL91_RS04570	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL91_RS04575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL91_RS04580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL91_RS04585	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL91_RS04590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL91_RS04620	COG3121	Chaperone
LGL91_RS04650	COG2501	S4 domain
LGL91_RS04655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL91_RS04670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL91_RS04675	COG1393	Belongs to the ArsC family
LGL91_RS04685	COG1022	Amp-dependent synthetase and ligase
LGL91_RS04740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL91_RS04750	COG1215	transferase activity, transferring glycosyl groups
LGL91_RS04770	COG3250	beta-galactosidase activity
LGL91_RS04785	COG1309	transcriptional regulator
LGL91_RS04815	COG2197	response regulator
LGL91_RS04820	COG1278	Cold shock
LGL91_RS04840	COG3706	GGDEF domain
LGL91_RS04850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL91_RS04860	COG2921	Belongs to the UPF0250 family
LGL91_RS04865	COG1686	Belongs to the peptidase S11 family
LGL91_RS04870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL91_RS04875	COG0772	Belongs to the SEDS family
LGL91_RS04880	COG0768	penicillin binding
LGL91_RS04885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL91_RS04890	COG0799	negative regulation of ribosome biogenesis
LGL91_RS04895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL91_RS04900	COG1466	dna polymerase III delta subunit
LGL91_RS04905	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL91_RS04915	COG2888	peptidyl-tyrosine sulfation
LGL91_RS04920	COG1126	abc transporter atp-binding protein
LGL91_RS04925	COG0765	amino acid transport
LGL91_RS04930	COG0765	amino acid transport
LGL91_RS04940	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL91_RS04945	COG4535	Mg2 and Co2 transporter CorC
LGL91_RS04950	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL91_RS04955	COG1702	phosphate starvation-inducible protein PhoH
LGL91_RS04960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL91_RS04965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL91_RS05000	COG0367	asparagine synthase
LGL91_RS05005	COG0647	UMP catabolic process
LGL91_RS05010	COG1940	carbohydrate kinase activity
LGL91_RS05010	COG1846	Transcriptional regulator
LGL91_RS05015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL91_RS05025	COG2190	(PTS) system
LGL91_RS05025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_RS05025	COG1263	PTS System
LGL91_RS05050	COG0735	belongs to the Fur family
LGL91_RS05060	COG0840	transmembrane signaling receptor activity
LGL91_RS05070	COG0596	Alpha beta hydrolase
LGL91_RS05075	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL91_RS05080	COG0033	Phosphoglucomutase
LGL91_RS05090	COG0745	RESPONSE REGULATOR receiver
LGL91_RS05095	COG2205	protein histidine kinase activity
LGL91_RS05100	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL91_RS05105	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL91_RS05125	COG3272	Protein of unknown function (DUF1722)
LGL91_RS05130	COG0415	Belongs to the DNA photolyase family
LGL91_RS05135	COG5212	phosphodiesterase
LGL91_RS05140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL91_RS05145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL91_RS05150	COG1984	allophanate hydrolase subunit 2
LGL91_RS05155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL91_RS05190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL91_RS05195	COG1053	succinate dehydrogenase
LGL91_RS05200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL91_RS05205	COG0567	Dehydrogenase, E1 component
LGL91_RS05210	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL91_RS05215	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL91_RS05220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL91_RS05230	COG1271	oxidase subunit
LGL91_RS05235	COG1294	oxidase, subunit
LGL91_RS05240	COG4890	Cyd operon protein YbgT
LGL91_RS05245	COG3790	cyd operon protein YbgE
LGL91_RS05250	COG0824	Thioesterase
LGL91_RS05255	COG0811	peptide transport
LGL91_RS05260	COG0848	biopolymer transport protein
LGL91_RS05265	COG3064	Membrane
LGL91_RS05265	COG3064	Membrane
LGL91_RS05270	COG0823	Involved in the tonB-independent uptake of proteins
LGL91_RS05275	COG2885	chlorophyll binding
LGL91_RS05280	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL91_RS05320	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL91_RS05330	COG2205	protein histidine kinase activity
LGL91_RS05330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_RS05340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL91_RS05345	COG0588	phosphoglycerate mutase activity
LGL91_RS05355	COG2017	converts alpha-aldose to the beta-anomer
LGL91_RS05365	COG1085	galactose-1-phosphate uridylyltransferase
LGL91_RS05370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL91_RS05385	COG3585	molybdate ion transport
LGL91_RS05385	COG2005	Transcriptional regulator
LGL91_RS05395	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL91_RS05400	COG4149	molybdate abc transporter
LGL91_RS05410	COG0561	phosphatase activity
LGL91_RS05415	COG2706	6-phosphogluconolactonase activity
LGL91_RS05430	COG0156	8-amino-7-oxononanoate synthase activity
LGL91_RS05435	COG2226	methyltransferase
LGL91_RS05450	COG0556	nucleotide-excision repair
LGL91_RS05455	COG4628	conserved protein (DUF2132)
LGL91_RS05470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_RS05475	COG1120	ATPase activity
LGL91_RS05480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL91_RS05485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL91_RS05495	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL91_RS05500	COG0314	molybdopterin synthase activity
LGL91_RS05505	COG0670	Belongs to the BI1 family
LGL91_RS05510	COG0842	Transport permease protein
LGL91_RS05515	COG0842	Transport permease protein
LGL91_RS05520	COG1131	(ABC) transporter
LGL91_RS05525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_RS05530	COG1309	transcriptional regulator
LGL91_RS05535	COG0513	Belongs to the DEAD box helicase family
LGL91_RS05540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL91_RS05550	COG1686	Belongs to the peptidase S11 family
LGL91_RS05555	COG0277	FAD linked oxidase domain protein
LGL91_RS05575	COG2261	transglycosylase associated protein
LGL91_RS05585	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL91_RS05595	COG3639	organic phosphonate transmembrane transporter activity
LGL91_RS05600	COG4807	Protein conserved in bacteria
LGL91_RS05605	COG2897	thiosulfate sulfurtransferase activity
LGL91_RS05610	COG1732	Glycine betaine
LGL91_RS05620	COG1174	glycine betaine transport
LGL91_RS05625	COG1125	glycine betaine transport
LGL91_RS05630	COG1174	glycine betaine transport
LGL91_RS05635	COG0531	amino acid
LGL91_RS05640	COG1982	Orn Lys Arg decarboxylase major
LGL91_RS05650	COG0697	spore germination
LGL91_RS05665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL91_RS05670	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL91_RS05675	COG1126	abc transporter atp-binding protein
LGL91_RS05680	COG0765	amino acid transport
LGL91_RS05685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_RS05705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL91_RS05710	COG2239	Acts as a magnesium transporter
LGL91_RS05715	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL91_RS05720	COG0488	(ABC) transporter
LGL91_RS05725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL91_RS05730	COG0303	'Molybdopterin
LGL91_RS05750	COG0583	DNA-binding transcription factor activity
LGL91_RS05755	COG0477	Major facilitator Superfamily
LGL91_RS05760	COG0302	gtp cyclohydrolase
LGL91_RS05765	COG2311	Membrane
LGL91_RS05790	COG2949	membrane
LGL91_RS05795	COG0281	malic enzyme
LGL91_RS05805	COG0583	DNA-binding transcription factor activity
LGL91_RS05815	COG1346	cytolysis
LGL91_RS05820	COG1380	Effector of murein hydrolase LrgA
LGL91_RS05830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL91_RS05830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL91_RS05835	COG0489	protein tyrosine kinase activity
LGL91_RS05840	COG0572	uridine kinase
LGL91_RS05845	COG0717	Belongs to the dCTP deaminase family
LGL91_RS05850	COG2982	Protein involved in outer membrane biogenesis
LGL91_RS05855	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL91_RS05860	COG1253	flavin adenine dinucleotide binding
LGL91_RS05865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL91_RS05870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL91_RS05875	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL91_RS05885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL91_RS05885	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL91_RS05895	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL91_RS05905	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL91_RS05905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL91_RS05910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL91_RS05915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL91_RS05930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_RS05935	COG0625	glutathione transferase activity
LGL91_RS05950	COG0626	cystathionine gamma-synthase activity
LGL91_RS05960	COG1686	Belongs to the peptidase S11 family
LGL91_RS05965	COG1760	l-serine dehydratase
LGL91_RS05970	COG0814	amino acid
LGL91_RS05975	COG1349	DNA-binding transcription factor activity
LGL91_RS05985	COG0671	phosphoesterase, PA-phosphatase related
LGL91_RS05995	COG0569	domain protein
LGL91_RS05995	COG2985	domain, Protein
LGL91_RS06015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL91_RS06020	COG3842	ATPase activity
LGL91_RS06025	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL91_RS06030	COG1177	transmembrane transport
LGL91_RS06045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_RS06050	COG4160	amino acid transport
LGL91_RS06055	COG4215	(ABC) transporter
LGL91_RS06060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_RS06065	COG1126	abc transporter atp-binding protein
LGL91_RS06075	COG0393	Putative heavy-metal-binding
LGL91_RS06080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_RS06085	COG0702	epimerase
LGL91_RS06090	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL91_RS06095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL91_RS06100	COG1151	hydroxylamine reductase activity
LGL91_RS06105	COG2431	L-lysine efflux transmembrane transporter activity
LGL91_RS06110	COG3593	DNA synthesis involved in DNA repair
LGL91_RS06115	COG2990	Protein conserved in bacteria
LGL91_RS06120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_RS06130	COG1278	Cold shock
LGL91_RS06135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL91_RS06140	COG0542	response to heat
LGL91_RS06145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL91_RS06155	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL91_RS06165	COG0492	ferredoxin-NADP+ reductase activity
LGL91_RS06170	COG1522	sequence-specific DNA binding
LGL91_RS06175	COG3107	peptidoglycan biosynthetic process
LGL91_RS06175	COG1674	ftsk spoiiie
LGL91_RS06180	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL91_RS06185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL91_RS06190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL91_RS06195	COG2814	Major facilitator Superfamily
LGL91_RS06200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL91_RS06205	COG1882	Formate acetyltransferase
LGL91_RS06210	COG2116	formate transmembrane transporter activity
LGL91_RS06215	COG1944	ATP diphosphatase activity
LGL91_RS06220	COG0252	asparaginase activity
LGL91_RS06230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL91_RS06240	COG0539	negative regulation of cytoplasmic translation
LGL91_RS06250	COG0658	competence protein
LGL91_RS06250	COG2333	competence protein COMEC
LGL91_RS06260	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL91_RS06265	COG5383	Protein conserved in bacteria
LGL91_RS06275	COG1278	Cold shock
LGL91_RS06280	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL91_RS06285	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL91_RS06290	COG3173	Aminoglycoside phosphotransferase
LGL91_RS06295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL91_RS06300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL91_RS06305	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL91_RS06315	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL91_RS06320	COG2989	Protein conserved in bacteria
LGL91_RS06325	COG3108	Peptidase M15
LGL91_RS06330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL91_RS06335	COG1448	Aminotransferase
LGL91_RS06350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL91_RS06355	COG0308	aminopeptidase N
LGL91_RS06360	COG0167	dihydroorotate dehydrogenase activity
LGL91_RS06370	COG0633	Ferredoxin
LGL91_RS06370	COG3217	Mosc domain protein beta barrel domain protein
LGL91_RS06375	COG0116	Belongs to the methyltransferase superfamily
LGL91_RS06375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL91_RS06380	COG0488	(ABC) transporter
LGL91_RS06385	COG2995	paraquat-inducible protein a
LGL91_RS06390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL91_RS06390	COG3008	intermembrane lipid transfer
LGL91_RS06395	COG3009	Protein conserved in bacteria
LGL91_RS06400	COG3130	regulation of translation
LGL91_RS06405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL91_RS06410	COG1067	ATP-dependent peptidase activity
LGL91_RS06415	COG3120	sequence-specific DNA binding
LGL91_RS06425	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL91_RS06430	COG3070	regulator of competence-specific genes
LGL91_RS06435	COG1289	transmembrane transporter activity
LGL91_RS06440	COG3304	Inner membrane component domain
LGL91_RS06445	COG0210	DNA helicase
LGL91_RS06450	COG1803	Methylglyoxal synthase
LGL91_RS06460	COG1832	CoA-binding protein
LGL91_RS06465	COG3785	DNA binding
LGL91_RS06470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL91_RS06475	COG1254	Belongs to the acylphosphatase family
LGL91_RS06480	COG2920	part of a sulfur-relay system
LGL91_RS06490	COG0288	reversible hydration of carbon dioxide
LGL91_RS06510	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL91_RS06515	COG2943	transferase activity, transferring hexosyl groups
LGL91_RS06520	COG0346	lactoylglutathione lyase activity
LGL91_RS06535	COG1560	Kdo2-lipid A biosynthetic process
LGL91_RS06545	COG0628	permease
LGL91_RS06570	COG0418	dihydroorotase activity
LGL91_RS06585	COG1530	ribonuclease E activity
LGL91_RS06590	COG0564	pseudouridine synthase activity
LGL91_RS06595	COG0424	maF-like protein
LGL91_RS06600	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL91_RS06605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL91_RS06615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL91_RS06620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL91_RS06630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL91_RS06635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL91_RS06640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL91_RS06645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL91_RS06650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL91_RS06655	COG0470	DNA polymerase III
LGL91_RS06660	COG0084	hydrolase, TatD family'
LGL91_RS06665	COG1263	PTS System
LGL91_RS06665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_RS06670	COG0537	adenosine 5'-monophosphoramidase activity
LGL91_RS06675	COG5633	Lipoprotein
LGL91_RS06680	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL91_RS06695	COG3150	esterase
LGL91_RS06700	COG1252	NADH dehydrogenase
LGL91_RS06705	COG3134	Outer membrane lipoprotein
LGL91_RS06710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL91_RS06715	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL91_RS06725	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL91_RS06745	COG2850	peptidyl-arginine hydroxylation
LGL91_RS06750	COG2205	protein histidine kinase activity
LGL91_RS06755	COG0745	RESPONSE REGULATOR receiver
LGL91_RS06765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL91_RS06770	COG2915	High frequency lysogenization protein hflD homolog
LGL91_RS06775	COG0482	sulfurtransferase activity
LGL91_RS06785	COG1187	pseudouridine synthase activity
LGL91_RS06790	COG0538	isocitrate dehydrogenase activity
LGL91_RS06795	COG2771	luxR family
LGL91_RS06800	COG3916	Acyl-homoserine-lactone synthase
LGL91_RS06805	COG2723	6-phospho-beta-galactosidase activity
LGL91_RS06810	COG0339	signal peptide processing
LGL91_RS06820	COG3493	citrate carrier protein
LGL91_RS06825	COG4565	transcriptional regulatory protein
LGL91_RS06830	COG3290	protein histidine kinase activity
LGL91_RS06835	COG0471	metal ion transport
LGL91_RS06875	COG4977	sequence-specific DNA binding
LGL91_RS06880	COG1702	phosphate starvation-inducible protein PhoH
LGL91_RS06885	COG0387	Pfam Sodium calcium exchanger
LGL91_RS06890	COG2375	cellular response to nickel ion
LGL91_RS06895	COG3850	Histidine kinase
LGL91_RS06905	COG1294	oxidase, subunit
LGL91_RS06910	COG1271	oxidase subunit
LGL91_RS06915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL91_RS06920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL91_RS06925	COG3138	arginine N-succinyltransferase
LGL91_RS06935	COG3724	N-succinylarginine dihydrolase activity
LGL91_RS06955	COG1228	amidohydrolase
LGL91_RS06965	COG0402	S-adenosylhomocysteine deaminase activity
LGL91_RS06985	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL91_RS06990	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL91_RS06995	COG3383	formate dehydrogenase (NAD+) activity
LGL91_RS07000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_RS07005	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL91_RS07015	COG3260	NADH ubiquinone oxidoreductase 20
LGL91_RS07020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_RS07025	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL91_RS07025	COG3261	NADH dehydrogenase
LGL91_RS07030	COG0650	Formate hydrogenlyase subunit 4
LGL91_RS07035	COG0651	ATP synthesis coupled electron transport
LGL91_RS07040	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_RS07050	COG0375	protein maturation
LGL91_RS07055	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL91_RS07060	COG0298	carbon dioxide binding
LGL91_RS07065	COG0409	Hydrogenase expression formation protein
LGL91_RS07070	COG0309	Hydrogenase expression formation protein (HypE)
LGL91_RS07090	COG0012	GTP binding
LGL91_RS07100	COG0193	aminoacyl-tRNA hydrolase activity
LGL91_RS07110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL91_RS07120	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL91_RS07125	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL91_RS07130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL91_RS07135	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL91_RS07150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL91_RS07155	COG0659	secondary active sulfate transmembrane transporter activity
LGL91_RS07160	COG3706	GGDEF domain
LGL91_RS07185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL91_RS07195	COG3381	protein complex oligomerization
LGL91_RS07215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL91_RS07225	COG0673	inositol 2-dehydrogenase activity
LGL91_RS07230	COG0728	peptidoglycan biosynthetic process
LGL91_RS07265	COG3102	Protein conserved in bacteria
LGL91_RS07270	COG3142	Participates in the control of copper homeostasis
LGL91_RS07285	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL91_RS07290	COG1801	Protein of unknown function DUF72
LGL91_RS07300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL91_RS07305	COG0494	nUDIX hydrolase
LGL91_RS07315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL91_RS07325	COG2255	four-way junction helicase activity
LGL91_RS07330	COG3104	oligopeptide transport
LGL91_RS07335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL91_RS07340	COG1121	(ABC) transporter
LGL91_RS07345	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL91_RS07350	COG0739	heme binding
LGL91_RS07355	COG1560	Kdo2-lipid A biosynthetic process
LGL91_RS07360	COG0469	pyruvate kinase activity
LGL91_RS07365	COG1737	Transcriptional regulator
LGL91_RS07370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL91_RS07375	COG0800	Aldolase
LGL91_RS07385	COG2076	Multidrug Resistance protein
LGL91_RS07390	COG0251	oxidation-reduction process
LGL91_RS07395	COG1199	ATP-dependent helicase activity
LGL91_RS07400	COG1214	PFAM Peptidase M22, glycoprotease
LGL91_RS07410	COG0318	PFAM AMP-dependent synthetase and ligase
LGL91_RS07415	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL91_RS07420	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL91_RS07425	COG2894	cell division
LGL91_RS07430	COG0850	regulation of cytokinetic process
LGL91_RS07435	COG3100	YcgL domain-containing protein
LGL91_RS07440	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL91_RS07445	COG2983	Belongs to the UPF0260 family
LGL91_RS07465	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL91_RS07475	COG2719	SpoVR family
LGL91_RS07480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL91_RS07485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL91_RS07490	COG2814	Major facilitator Superfamily
LGL91_RS07500	COG2200	EAL domain
LGL91_RS07500	COG2199	diguanylate cyclase activity
LGL91_RS07500	COG2202	Pas domain
LGL91_RS07525	COG2718	Belongs to the UPF0229 family
LGL91_RS07530	COG2766	serine protein kinase
LGL91_RS07540	COG3713	MltA-interacting MipA family protein
LGL91_RS07545	COG2194	sulfuric ester hydrolase activity
LGL91_RS07560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL91_RS07565	COG3139	Protein of unknown function (DUF1315)
LGL91_RS07570	COG1335	isochorismatase
LGL91_RS07575	COG0252	asparaginase activity
LGL91_RS07580	COG0616	signal peptide processing
LGL91_RS07585	COG0778	Nitroreductase
LGL91_RS07595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL91_RS07605	COG0494	nUDIX hydrolase
LGL91_RS07610	COG0708	Exodeoxyribonuclease III
LGL91_RS07645	COG0788	formyltetrahydrofolate deformylase activity
LGL91_RS07655	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL91_RS07660	COG0745	RESPONSE REGULATOR receiver
LGL91_RS07680	COG1012	belongs to the aldehyde dehydrogenase family
LGL91_RS07680	COG1454	alcohol dehydrogenase
LGL91_RS07690	COG2095	MarC family integral membrane protein
LGL91_RS07710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL91_RS07725	COG3099	Belongs to the UPF0263 family
LGL91_RS07730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL91_RS07750	COG2350	Protein conserved in bacteria
LGL91_RS07770	COG3710	Transcriptional regulator
LGL91_RS07805	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL91_RS07830	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL91_RS07835	COG3047	cAMP biosynthetic process
LGL91_RS07850	COG0133	tryptophan synthase activity
LGL91_RS07855	COG0135	phosphoribosylanthranilate isomerase activity
LGL91_RS07855	COG0134	indole-3-glycerol-phosphate synthase activity
LGL91_RS07865	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL91_RS07875	COG0613	PHP domain protein
LGL91_RS07880	COG0009	L-threonylcarbamoyladenylate synthase
LGL91_RS07885	COG1187	pseudouridine synthase activity
LGL91_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_RS07900	COG0616	signal peptide processing
LGL91_RS07915	COG0583	DNA-binding transcription factor activity
LGL91_RS07935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL91_RS07945	COG0671	phosphoesterase, PA-phosphatase related
LGL91_RS07950	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL91_RS07955	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL91_RS07975	COG0023	Translation Initiation Factor
LGL91_RS07985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL91_RS07990	COG5002	protein histidine kinase activity
LGL91_RS07990	COG5001	Diguanylate cyclase
LGL91_RS07990	COG3447	MASE1 domain protein
LGL91_RS07995	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL91_RS08000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL91_RS08010	COG4659	FMN binding
LGL91_RS08020	COG3708	Transcriptional regulator
LGL91_RS08020	COG2207	Transcriptional regulator
LGL91_RS08035	COG4657	Part of a membrane complex involved in electron transport
LGL91_RS08045	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL91_RS08055	COG0673	inositol 2-dehydrogenase activity
LGL91_RS08060	COG0385	Bile acid
LGL91_RS08065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL91_RS08085	COG5339	Protein conserved in bacteria
LGL91_RS08090	COG1482	cell wall glycoprotein biosynthetic process
LGL91_RS08095	COG0114	fumarate hydratase activity
LGL91_RS08120	COG1940	carbohydrate kinase activity
LGL91_RS08125	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL91_RS08145	COG1742	UPF0060 membrane protein
LGL91_RS08150	COG4221	oxidoreductase activity
LGL91_RS08155	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL91_RS08235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL91_RS08275	COG1011	Hydrolase
LGL91_RS08285	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL91_RS08290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL91_RS08295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL91_RS08300	COG0589	response to stress
LGL91_RS08330	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL91_RS08335	COG3623	hexulose-6-phosphate isomerase
LGL91_RS08340	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL91_RS08345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL91_RS08355	COG0531	amino acid
LGL91_RS08365	COG0745	RESPONSE REGULATOR receiver
LGL91_RS08370	COG2205	protein histidine kinase activity
LGL91_RS08380	COG2207	Transcriptional regulator
LGL91_RS08385	COG1881	PFAM PEBP family protein
LGL91_RS08395	COG3591	Belongs to the peptidase S1B family
LGL91_RS08400	COG1643	Atp-dependent helicase
LGL91_RS08405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL91_RS08410	COG3784	Protein of unknown function (DUF1318)
LGL91_RS08425	COG2911	Protein conserved in bacteria
LGL91_RS08430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL91_RS08435	COG3187	Heat shock protein
LGL91_RS08440	COG3042	response to heat
LGL91_RS08445	COG1285	pathogenesis
LGL91_RS08455	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL91_RS08455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL91_RS08455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_RS08455	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL91_RS08470	COG4166	transmembrane transport
LGL91_RS08475	COG2866	Carboxypeptidase
LGL91_RS08480	COG4948	Mandelate Racemase Muconate Lactonizing
LGL91_RS08485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL91_RS08495	COG5642	Protein of unknown function (DUF2384)
LGL91_RS08500	COG5654	RES domain protein
LGL91_RS08505	COG3768	UPF0283 membrane protein
LGL91_RS08510	COG3106	COG3106 Predicted ATPase
LGL91_RS08515	COG1983	PspC domain protein
LGL91_RS08525	COG1842	Phage shock protein A
LGL91_RS08530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LGL91_RS08545	COG4166	transmembrane transport
LGL91_RS08555	COG4171	peptide transport system, permease
LGL91_RS08560	COG4172	Belongs to the ABC transporter superfamily
LGL91_RS08565	COG4172	Belongs to the ABC transporter superfamily
LGL91_RS08575	COG3104	oligopeptide transport
LGL91_RS08585	COG0484	heat shock protein binding
LGL91_RS08630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL91_RS08635	COG3133	Outer membrane lipoprotein
LGL91_RS08640	COG1846	Transcriptional regulator
LGL91_RS08650	COG4989	oxidoreductase activity
LGL91_RS08655	COG3313	Fe-S protein
LGL91_RS08660	COG2194	sulfuric ester hydrolase activity
LGL91_RS08665	COG1309	transcriptional regulator
LGL91_RS08670	COG1902	pentaerythritol trinitrate reductase activity
LGL91_RS08685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL91_RS08690	COG0791	NLP P60 protein
LGL91_RS08695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL91_RS08705	COG1609	Transcriptional regulator
LGL91_RS08710	COG0583	DNA-binding transcription factor activity
LGL91_RS08715	COG2814	Major facilitator Superfamily
LGL91_RS08720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL91_RS08725	COG0307	riboflavin synthase, alpha
LGL91_RS08760	COG1376	ErfK ybiS ycfS ynhG family protein
LGL91_RS08760	COG1388	LysM domain
LGL91_RS08765	COG2166	iron-sulfur cluster assembly
LGL91_RS08775	COG0719	Fe-S assembly protein
LGL91_RS08780	COG0396	ATPase activity
LGL91_RS08785	COG0719	Fe-S assembly protein
LGL91_RS08790	COG0316	Belongs to the HesB IscA family
LGL91_RS08795	COG2050	protein possibly involved in aromatic compounds catabolism
LGL91_RS08800	COG0247	lactate metabolic process
LGL91_RS08800	COG0277	FAD linked oxidase domain protein
LGL91_RS08805	COG0628	permease
LGL91_RS08815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL91_RS08815	COG0574	Belongs to the PEP-utilizing enzyme family
LGL91_RS08820	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL91_RS08825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL91_RS08835	COG4771	TonB-dependent receptor
LGL91_RS08840	COG3720	iron ion transport
LGL91_RS08845	COG4558	Periplasmic binding protein
LGL91_RS08850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_RS08855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL91_RS08865	COG0095	Lipoate-protein ligase
LGL91_RS08870	COG0791	NLP P60 protein
LGL91_RS08875	COG2076	Multidrug Resistance protein
LGL91_RS08880	COG2076	Multidrug Resistance protein
LGL91_RS08885	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL91_RS08900	COG0463	Glycosyl transferase, family 2
LGL91_RS08905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL91_RS08915	COG4139	cobalamin transport
LGL91_RS08985	COG0776	regulation of translation
LGL91_RS09055	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL91_RS09060	COG1121	(ABC) transporter
LGL91_RS09065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL91_RS09070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL91_RS09075	COG3001	Fructosamine kinase
LGL91_RS09085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL91_RS09105	COG1823	symporter activity
LGL91_RS09110	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL91_RS09120	COG2814	Major facilitator Superfamily
LGL91_RS09130	COG0501	Belongs to the peptidase M48B family
LGL91_RS09135	COG0793	Belongs to the peptidase S41A family
LGL91_RS09145	COG1956	GAF domain-containing protein
LGL91_RS09150	COG2995	paraquat-inducible protein a
LGL91_RS09155	COG3008	intermembrane lipid transfer
LGL91_RS09160	COG4251	negative regulation of phosphorylation
LGL91_RS09160	COG5001	Diguanylate cyclase
LGL91_RS09160	COG2203	Gaf domain
LGL91_RS09160	COG3706	GGDEF domain
LGL91_RS09295	COG4695	Portal protein
LGL91_RS09390	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL91_RS09450	COG4974	Belongs to the 'phage' integrase family
LGL91_RS09460	COG1276	copper resistance
LGL91_RS09465	COG2372	response to copper ion
LGL91_RS09470	COG1528	Iron-storage protein
LGL91_RS09485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL91_RS09490	COG1770	oligopeptidase
LGL91_RS09500	COG3097	Belongs to the UPF0267 family
LGL91_RS09505	COG3141	response to X-ray
LGL91_RS09510	COG0513	Belongs to the DEAD box helicase family
LGL91_RS09530	COG0494	nUDIX hydrolase
LGL91_RS09535	COG1760	l-serine dehydratase
LGL91_RS09540	COG1253	flavin adenine dinucleotide binding
LGL91_RS09545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_RS09545	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_RS09550	COG3715	PTS system
LGL91_RS09555	COG3716	PTS system mannose fructose sorbose family IID component
LGL91_RS09560	COG4811	Protein of unknown function (DUF986)
LGL91_RS09565	COG1971	Probably functions as a manganese efflux pump
LGL91_RS09585	COG1960	acyl-CoA dehydrogenase activity
LGL91_RS09595	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL91_RS09625	COG2226	methyltransferase
LGL91_RS09635	COG1496	oxidoreductase activity
LGL91_RS09660	COG1113	amino acid transport
LGL91_RS09705	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LGL91_RS09760	COG4386	tail sheath protein
LGL91_RS09785	COG4397	Mu-like prophage major head subunit gpT
LGL91_RS09810	COG4383	Mu-like prophage protein gp29
LGL91_RS09865	COG4382	Mu-like prophage protein Gp16
LGL91_RS09930	COG3423	Transcriptional regulator
LGL91_RS09970	COG2207	Transcriptional regulator
LGL91_RS09990	COG1132	(ABC) transporter
LGL91_RS10000	COG5001	Diguanylate cyclase
LGL91_RS10000	COG3706	GGDEF domain
LGL91_RS10000	COG2203	Gaf domain
LGL91_RS10000	COG4251	negative regulation of phosphorylation
LGL91_RS10020	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL91_RS10040	COG1278	Cold shock
LGL91_RS10055	COG2169	Transcriptional regulator
LGL91_RS10055	COG1917	Cupin 2, conserved barrel domain protein
LGL91_RS10060	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL91_RS10065	COG2723	6-phospho-beta-galactosidase activity
LGL91_RS10070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL91_RS10075	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL91_RS10080	COG1187	pseudouridine synthase activity
LGL91_RS10090	COG3122	Protein conserved in bacteria
LGL91_RS10095	COG1757	Na H antiporter
LGL91_RS10110	COG2235	arginine
LGL91_RS10135	COG0076	glutamate decarboxylase activity
LGL91_RS10140	COG0531	amino acid
LGL91_RS10175	COG2153	protein acetylation
LGL91_RS10180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL91_RS10215	COG0840	transmembrane signaling receptor activity
LGL91_RS10220	COG2801	Transposase and inactivated derivatives
LGL91_RS10240	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL91_RS10280	COG3646	Phage regulatory protein
LGL91_RS10295	COG3772	lysozyme
LGL91_RS10320	COG1403	HNH endonuclease
LGL91_RS10335	COG4626	Terminase
LGL91_RS10335	COG1802	Transcriptional regulator
LGL91_RS10380	COG5532	Uncharacterized conserved protein (DUF2303)
LGL91_RS10385	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL91_RS10435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL91_RS10440	COG0322	excinuclease ABC activity
LGL91_RS10445	COG2197	response regulator
LGL91_RS10470	COG1113	amino acid transport
LGL91_RS10480	COG0531	amino acid
LGL91_RS10485	COG3710	Transcriptional regulator
LGL91_RS10490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL91_RS10495	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL91_RS10495	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL91_RS10495	COG0506	proline dehydrogenase activity
LGL91_RS10500	COG1126	abc transporter atp-binding protein
LGL91_RS10505	COG0765	amino acid transport
LGL91_RS10510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_RS10515	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL91_RS10525	COG1191	sigma factor activity
LGL91_RS10565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL91_RS10570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL91_RS10585	COG1677	Flagellar hook-basal body complex protein FliE
LGL91_RS10595	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL91_RS10605	COG1157	protein secretion by the type III secretion system
LGL91_RS10620	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL91_RS10690	COG1749	Flagellar hook protein flgE
LGL91_RS10700	COG1558	bacterial-type flagellum-dependent cell motility
LGL91_RS10705	COG1815	bacterial-type flagellum-dependent cell motility
LGL91_RS10715	COG2747	anti-sigma28 factor FlgM
LGL91_RS10720	COG3418	PFAM FlgN family protein
LGL91_RS10730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL91_RS10735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL91_RS10740	COG1404	Belongs to the peptidase S8 family
LGL91_RS10740	COG4935	Belongs to the peptidase S8 family
LGL91_RS10745	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL91_RS10750	COG0745	RESPONSE REGULATOR receiver
LGL91_RS10760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL91_RS10765	COG0840	transmembrane signaling receptor activity
LGL91_RS10770	COG0840	transmembrane signaling receptor activity
LGL91_RS10775	COG0835	chemotaxis
LGL91_RS10780	COG2198	Histidine kinase
LGL91_RS10780	COG0643	Histidine kinase
LGL91_RS10785	COG1360	Flagellar Motor Protein
LGL91_RS10805	COG0589	response to stress
LGL91_RS10815	COG1285	pathogenesis
LGL91_RS10820	COG0840	transmembrane signaling receptor activity
LGL91_RS10840	COG1609	Transcriptional regulator
LGL91_RS10850	COG3321	synthase
LGL91_RS10850	COG0604	alcohol dehydrogenase
LGL91_RS10850	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_RS10900	COG0471	metal ion transport
LGL91_RS10915	COG3051	citrate lyase alpha subunit
LGL91_RS10920	COG2301	Belongs to the HpcH HpaI aldolase family
LGL91_RS10925	COG3052	prosthetic group binding
LGL91_RS10930	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL91_RS10935	COG3290	protein histidine kinase activity
LGL91_RS10940	COG4565	transcriptional regulatory protein
LGL91_RS10955	COG2271	Major facilitator Superfamily
LGL91_RS10960	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL91_RS10970	COG3842	ATPase activity
LGL91_RS10985	COG0582	viral genome integration into host DNA
LGL91_RS11010	COG1475	DNA binding
LGL91_RS11135	COG1289	transmembrane transporter activity
LGL91_RS11145	COG2925	Exonuclease
LGL91_RS11150	COG0531	amino acid
LGL91_RS11155	COG4771	TonB-dependent receptor
LGL91_RS11165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_RS11175	COG0833	amino acid
LGL91_RS11180	COG0583	DNA-binding transcription factor activity
LGL91_RS11190	COG2855	membrane
LGL91_RS11195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL91_RS11200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL91_RS11200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL91_RS11200	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL91_RS11205	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL91_RS11220	COG3005	denitrification pathway
LGL91_RS11225	COG0243	molybdopterin cofactor binding
LGL91_RS11245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL91_RS11255	COG0246	Mannitol dehydrogenase
LGL91_RS11265	COG0523	cobalamin synthesis protein
LGL91_RS11270	COG0671	phosphoesterase, PA-phosphatase related
LGL91_RS11275	COG0791	NLP P60 protein
LGL91_RS11280	COG2200	EAL domain
LGL91_RS11285	COG4166	transmembrane transport
LGL91_RS11290	COG4174	ABC transporter (Permease)
LGL91_RS11295	COG4239	(ABC) transporter, permease
LGL91_RS11300	COG4172	Belongs to the ABC transporter superfamily
LGL91_RS11310	COG2814	Major facilitator Superfamily
LGL91_RS11315	COG1187	pseudouridine synthase activity
LGL91_RS11320	COG1061	Type III restriction enzyme res subunit
LGL91_RS11335	COG3082	Protein of unknown function (DUF1414)
LGL91_RS11340	COG3083	sulfuric ester hydrolase activity
LGL91_RS11370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL91_RS11395	COG2223	nitrite transmembrane transporter activity
LGL91_RS11400	COG2198	Histidine kinase
LGL91_RS11400	COG0642	Histidine kinase
LGL91_RS11410	COG2205	protein histidine kinase activity
LGL91_RS11410	COG0784	Response regulator, receiver
LGL91_RS11420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL91_RS11425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL91_RS11435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL91_RS11445	COG4574	serine-type endopeptidase inhibitor activity
LGL91_RS11455	COG2246	polysaccharide biosynthetic process
LGL91_RS11470	COG0814	amino acid
LGL91_RS11495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL91_RS11500	COG0596	Alpha beta hydrolase
LGL91_RS11505	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL91_RS11510	COG1169	isochorismate synthase
LGL91_RS11515	COG4575	ribosome binding
LGL91_RS11530	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_RS11535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL91_RS11545	COG0839	Belongs to the complex I subunit 6 family
LGL91_RS11550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_RS11555	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL91_RS11560	COG1034	ATP synthesis coupled electron transport
LGL91_RS11580	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_RS11585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_RS11590	COG0583	DNA-binding transcription factor activity
LGL91_RS11595	COG0436	Aminotransferase
LGL91_RS11600	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL91_RS11605	COG0490	domain, Protein
LGL91_RS11605	COG0471	metal ion transport
LGL91_RS11615	COG3013	Belongs to the UPF0304 family
LGL91_RS11620	COG3092	negative regulation of chromosome organization
LGL91_RS11630	COG0857	belongs to the CobB CobQ family
LGL91_RS11630	COG0280	phosphate acetyltransferase
LGL91_RS11635	COG1609	Transcriptional regulator
LGL91_RS11650	COG3037	sugar-specific permease SgaT UlaA
LGL91_RS11655	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL91_RS11660	COG0622	Phosphoesterase
LGL91_RS11670	COG0625	glutathione transferase activity
LGL91_RS11675	COG1090	epimerase
LGL91_RS11685	COG4160	amino acid transport
LGL91_RS11690	COG4215	(ABC) transporter
LGL91_RS11705	COG0163	prenyltransferase activity
LGL91_RS11710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL91_RS11715	COG1286	toxin biosynthetic process
LGL91_RS11720	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL91_RS11725	COG0285	dihydrofolate synthase activity
LGL91_RS11735	COG0586	Pfam SNARE associated Golgi protein
LGL91_RS11745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL91_RS11770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL91_RS11775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL91_RS11805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL91_RS11820	COG3101	peptidyl-lysine hydroxylation
LGL91_RS11825	COG0730	response to heat
LGL91_RS11830	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL91_RS11840	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL91_RS11845	COG2840	Smr protein MutS2
LGL91_RS11850	COG2062	phosphohistidine phosphatase, SixA
LGL91_RS11860	COG0183	Belongs to the thiolase family
LGL91_RS11865	COG3691	Protein conserved in bacteria
LGL91_RS11880	COG4235	cytochrome complex assembly
LGL91_RS11880	COG3088	subunit of a heme lyase
LGL91_RS11885	COG4235	cytochrome complex assembly
LGL91_RS11885	COG3088	subunit of a heme lyase
LGL91_RS11890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL91_RS11895	COG1138	Cytochrome C-type biogenesis protein
LGL91_RS11900	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL91_RS11905	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL91_RS11910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL91_RS11915	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL91_RS11930	COG0582	viral genome integration into host DNA
LGL91_RS11995	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL91_RS12000	COG2951	lytic endotransglycosylase activity
LGL91_RS12005	COG1598	PFAM Uncharacterised protein family UPF0150
LGL91_RS12015	COG3038	cytochrome b561
LGL91_RS12020	COG0436	Aminotransferase
LGL91_RS12030	COG3275	phosphorelay sensor kinase activity
LGL91_RS12035	COG3279	Response regulator of the LytR AlgR family
LGL91_RS12040	COG2223	nitrite transmembrane transporter activity
LGL91_RS12045	COG0837	glucose binding
LGL91_RS12065	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL91_RS12070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL91_RS12140	COG3530	Putative quorum-sensing-regulated virulence factor
LGL91_RS12145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL91_RS12155	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL91_RS12165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_RS12180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL91_RS12190	COG4208	sulfate ABC transporter
LGL91_RS12195	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL91_RS12200	COG4150	thiosulfate binding
LGL91_RS12210	COG1737	Transcriptional regulator
LGL91_RS12215	COG2731	YhcH YjgK YiaL family protein
LGL91_RS12230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL91_RS12235	COG2837	iron assimilation
LGL91_RS12245	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL91_RS12260	COG1671	Belongs to the UPF0178 family
LGL91_RS12265	COG0280	phosphate acetyltransferase
LGL91_RS12265	COG0281	malic enzyme
LGL91_RS12270	COG0494	nUDIX hydrolase
LGL91_RS12275	COG3005	denitrification pathway
LGL91_RS12280	COG3043	anaerobic respiration
LGL91_RS12285	COG0243	molybdopterin cofactor binding
LGL91_RS12290	COG3062	negative regulation of establishment of protein localization
LGL91_RS12295	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_RS12295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_RS12300	COG2197	response regulator
LGL91_RS12310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL91_RS12320	COG1605	Chorismate mutase
LGL91_RS12325	COG1393	Belongs to the ArsC family
LGL91_RS12330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL91_RS12335	COG1876	peptidase activity
LGL91_RS12345	COG0400	carboxylic ester hydrolase activity
LGL91_RS12365	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL91_RS12370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL91_RS12375	COG2716	regulation of RNA biosynthetic process
LGL91_RS12380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL91_RS12385	COG0628	permease
LGL91_RS12390	COG4783	chaperone-mediated protein folding
LGL91_RS12395	COG1393	Belongs to the ArsC family
LGL91_RS12400	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL91_RS12405	COG2233	PERMEase
LGL91_RS12410	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL91_RS12415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL91_RS12420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL91_RS12425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL91_RS12435	COG0581	inorganic phosphate transmembrane transporter activity
LGL91_RS12440	COG0573	inorganic phosphate transmembrane transporter activity
LGL91_RS12445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL91_RS12460	COG2239	Acts as a magnesium transporter
LGL91_RS12465	COG0443	Heat shock 70 kDa protein
LGL91_RS12475	COG3121	Chaperone
LGL91_RS12495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_RS12505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL91_RS12510	COG0477	Major facilitator Superfamily
LGL91_RS12515	COG2205	protein histidine kinase activity
LGL91_RS12520	COG0745	RESPONSE REGULATOR receiver
LGL91_RS12525	COG3422	double-strand break repair
LGL91_RS12530	COG0826	peptidase U32
LGL91_RS12535	COG1597	lipid kinase activity
LGL91_RS12550	COG0351	phosphomethylpyrimidine kinase
LGL91_RS12560	COG0519	Catalyzes the synthesis of GMP from XMP
LGL91_RS12560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL91_RS12565	COG0517	IMP dehydrogenase activity
LGL91_RS12565	COG0516	GMP reductase activity
LGL91_RS12570	COG1570	exodeoxyribonuclease VII activity
LGL91_RS12575	COG1645	bacterial-type flagellum-dependent swarming motility
LGL91_RS12585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL91_RS12590	COG2976	Protein conserved in bacteria
LGL91_RS12595	COG0124	histidyl-tRNA synthetase
LGL91_RS12615	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL91_RS12630	COG4953	penicillin-binding protein 1C
LGL91_RS12635	COG2373	Large extracellular alpha-helical protein
LGL91_RS12650	COG2975	iron-sulfur cluster assembly
LGL91_RS12655	COG0633	Ferredoxin
LGL91_RS12660	COG0443	Heat shock 70 kDa protein
LGL91_RS12675	COG0822	iron-sulfur transferase activity
LGL91_RS12685	COG1959	2 iron, 2 sulfur cluster binding
LGL91_RS12690	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL91_RS12700	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL91_RS12705	COG3683	transport system, periplasmic component
LGL91_RS12710	COG3711	transcriptional antiterminator
LGL91_RS12715	COG2814	Major facilitator Superfamily
LGL91_RS12725	COG1017	nitric oxide dioxygenase activity
LGL91_RS12725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL91_RS12730	COG2188	Transcriptional regulator
LGL91_RS12740	COG3457	Alanine racemase
LGL91_RS12745	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL91_RS12760	COG0347	Belongs to the P(II) protein family
LGL91_RS12765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL91_RS12765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL91_RS12770	COG2204	response regulator
LGL91_RS12775	COG3170	Tfp pilus assembly protein FimV
LGL91_RS12780	COG2205	protein histidine kinase activity
LGL91_RS12795	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL91_RS12805	COG0560	Phosphoserine phosphatase
LGL91_RS12810	COG1263	PTS System
LGL91_RS12810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_RS12820	COG1737	Transcriptional regulator
LGL91_RS12840	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL91_RS12915	COG0305	Participates in initiation and elongation during chromosome replication
LGL91_RS12920	COG1484	DNA-dependent DNA replication
LGL91_RS13070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_RS13080	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL91_RS13090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL91_RS13105	COG0481	GTPase activity
LGL91_RS13110	COG3086	response to oxidative stress
LGL91_RS13120	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL91_RS13130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL91_RS13140	COG0513	Belongs to the DEAD box helicase family
LGL91_RS13155	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL91_RS13165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL91_RS13170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL91_RS13175	COG0497	DNA recombination
LGL91_RS13180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL91_RS13190	COG2867	negative regulation of translational initiation
LGL91_RS13195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL91_RS13230	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL91_RS13295	COG0582	viral genome integration into host DNA
LGL91_RS13300	COG0582	viral genome integration into host DNA
LGL91_RS13335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL91_RS13415	COG1069	ribulokinase activity
LGL91_RS13425	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL91_RS13430	COG1129	ABC transporter
LGL91_RS13450	COG1620	l-lactate permease
LGL91_RS13455	COG1304	FMN binding
LGL91_RS13460	COG0579	oxidoreductase
LGL91_RS13465	COG1278	Cold shock
LGL91_RS13495	COG1780	Probably involved in ribonucleotide reductase function
LGL91_RS13500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL91_RS13510	COG4175	Glycine betaine
LGL91_RS13515	COG4176	ABC-type proline glycine betaine transport system permease component
LGL91_RS13520	COG2113	Glycine betaine
LGL91_RS13530	COG2814	Major facilitator Superfamily
LGL91_RS13535	COG1846	Transcriptional regulator
LGL91_RS13545	COG1566	PFAM secretion protein HlyD family protein
LGL91_RS13550	COG2814	Major facilitator Superfamily
LGL91_RS13555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL91_RS13560	COG3118	belongs to the thioredoxin family
LGL91_RS13570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL91_RS13570	COG1042	CoA-binding domain protein
LGL91_RS13570	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL91_RS13575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL91_RS13580	COG5544	Lipoprotein
LGL91_RS13605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL91_RS13615	COG2011	ABC-type metal ion transport system permease component
LGL91_RS13620	COG1464	Belongs to the NlpA lipoprotein family
LGL91_RS13630	COG1720	tRNA m6t6A37 methyltransferase activity
LGL91_RS13635	COG0442	prolyl-tRNA aminoacylation
LGL91_RS13640	COG3015	lipoprotein NlpE involved in copper resistance
LGL91_RS13650	COG4681	YaeQ
LGL91_RS13660	COG4568	rho-dependent transcription termination
LGL91_RS13675	COG0346	lactoylglutathione lyase activity
LGL91_RS13690	COG0825	malonyl-CoA metabolic process
LGL91_RS13695	COG0587	DNA-directed DNA polymerase activity
LGL91_RS13700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL91_RS13720	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL91_RS13725	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL91_RS13735	COG0750	zinc metalloprotease
LGL91_RS13740	COG0575	Belongs to the CDS family
LGL91_RS13760	COG0528	UMP kinase activity
LGL91_RS13765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL91_RS13780	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL91_RS13785	COG2171	N-acyltransferase activity
LGL91_RS13800	COG0564	pseudouridine synthase activity
LGL91_RS13805	COG3098	single-species biofilm formation
LGL91_RS13820	COG1611	Belongs to the LOG family
LGL91_RS13830	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL91_RS13835	COG2363	Small membrane protein
LGL91_RS13840	COG0583	DNA-binding transcription factor activity
LGL91_RS13850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL91_RS13855	COG2166	iron-sulfur cluster assembly
LGL91_RS13860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL91_RS13865	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL91_RS13885	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL91_RS13890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL91_RS13890	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL91_RS13895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL91_RS13900	COG1074	ATP-dependent DNA helicase activity
LGL91_RS13905	COG1025	Belongs to the peptidase M16 family
LGL91_RS13910	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL91_RS13915	COG4967	type IV pilus modification protein PilV
LGL91_RS13940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL91_RS13945	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL91_RS13955	COG3066	DNA modification
LGL91_RS13960	COG0861	Integral membrane protein TerC family
LGL91_RS13965	COG0667	Aldo Keto reductase
LGL91_RS13970	COG0477	Major facilitator Superfamily
LGL91_RS13975	COG0318	PFAM AMP-dependent synthetase and ligase
LGL91_RS13975	COG0204	Acyl-transferase
LGL91_RS13980	COG1609	Transcriptional regulator
LGL91_RS13990	COG0583	DNA-binding transcription factor activity
LGL91_RS13995	COG0583	DNA-binding transcription factor activity
LGL91_RS14050	COG2165	general secretion pathway protein
LGL91_RS14095	COG1127	ABC transporter
LGL91_RS14100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL91_RS14110	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL91_RS14120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL91_RS14125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL91_RS14130	COG4974	Belongs to the 'phage' integrase family
LGL91_RS14135	COG0716	FMN binding
LGL91_RS14145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL91_RS14155	COG1272	protein, Hemolysin III
LGL91_RS14175	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL91_RS14180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL91_RS14185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL91_RS14190	COG0006	proline dipeptidase activity
LGL91_RS14200	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL91_RS14210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL91_RS14215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL91_RS14220	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL91_RS14235	COG1279	arginine transmembrane transporter activity
LGL91_RS14245	COG0191	fructose-bisphosphate aldolase activity
LGL91_RS14250	COG0126	phosphoglycerate kinase activity
LGL91_RS14255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL91_RS14260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL91_RS14270	COG1166	arginine decarboxylase activity
LGL91_RS14275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL91_RS14290	COG0640	Transcriptional regulator
LGL91_RS14295	COG3091	SprT-like family
LGL91_RS14300	COG2356	endonuclease I
LGL91_RS14305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL91_RS14310	COG0189	ligase activity
LGL91_RS14315	COG1678	Uncharacterized ACR, COG1678
LGL91_RS14320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL91_RS14325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL91_RS14335	COG2805	Type II/IV secretion system protein
LGL91_RS14340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL91_RS14345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL91_RS14350	COG0762	integral membrane protein
LGL91_RS14355	COG1872	DUF167
LGL91_RS14360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL91_RS14365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL91_RS14380	COG3171	Protein conserved in bacteria
LGL91_RS14390	COG1194	a g-specific adenine glycosylase
LGL91_RS14395	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL91_RS14400	COG0741	lytic transglycosylase activity
LGL91_RS14485	COG0583	DNA-binding transcription factor activity
LGL91_RS14500	COG3730	PTS system glucitol sorbitol-specific
LGL91_RS14505	COG3732	PTS system glucitol sorbitol-specific
LGL91_RS14510	COG3731	PTS system glucitol sorbitol-specific IIA component
LGL91_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_RS14520	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_RS14525	COG1349	DNA-binding transcription factor activity
LGL91_RS14535	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL91_RS14540	COG1882	Formate acetyltransferase
LGL91_RS14545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL91_RS14550	COG0814	amino acid
LGL91_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_RS14570	COG1535	isochorismatase
LGL91_RS14570	COG3433	isochorismatase activity
LGL91_RS14575	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL91_RS14580	COG1169	isochorismate synthase
LGL91_RS14585	COG4592	Periplasmic binding protein
LGL91_RS14595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_RS14600	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_RS14605	COG1120	ATPase activity
LGL91_RS14615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL91_RS14620	COG3251	PFAM MbtH domain protein
LGL91_RS14630	COG4774	siderophore transport
LGL91_RS14635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL91_RS14665	COG4964	Belongs to the GSP D family
LGL91_RS14725	COG0848	biopolymer transport protein
LGL91_RS14730	COG0811	peptide transport
LGL91_RS14735	COG0626	cystathionine gamma-synthase activity
LGL91_RS14740	COG0586	Pfam SNARE associated Golgi protein
LGL91_RS14745	COG2207	Transcriptional regulator
LGL91_RS14750	COG1979	alcohol dehydrogenase
LGL91_RS14755	COG0656	L-ascorbic acid biosynthetic process
LGL91_RS14765	COG2132	Multicopper oxidase
LGL91_RS14775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGL91_RS14780	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL91_RS14785	COG0583	DNA-binding transcription factor activity
LGL91_RS14790	COG0187	DNA topoisomerase II activity
LGL91_RS14795	COG3150	esterase
LGL91_RS14800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL91_RS14805	COG3151	Protein conserved in bacteria
LGL91_RS14810	COG0494	nUDIX hydrolase
LGL91_RS14815	COG1538	Outer membrane efflux protein
LGL91_RS14820	COG5463	Belongs to the UPF0441 family
LGL91_RS14825	COG0754	glutathionylspermidine amidase activity
LGL91_RS14830	COG3384	dioxygenase
LGL91_RS14835	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL91_RS14845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL91_RS14845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL91_RS14855	COG3025	triphosphatase activity
LGL91_RS14860	COG4991	sh3 domain protein
LGL91_RS14865	COG0617	tRNA 3'-terminal CCA addition
LGL91_RS14870	COG1968	undecaprenyl-diphosphatase activity
LGL91_RS14875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL91_RS14880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL91_RS14885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL91_RS14890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL91_RS14895	COG0358	DNA primase activity
LGL91_RS14920	COG1201	RNA secondary structure unwinding
LGL91_RS14955	COG4983	Phage plasmid primase, P4 family domain protein
LGL91_RS15000	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_RS15025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL91_RS15055	COG3210	domain, Protein
LGL91_RS15060	COG2831	hemolysin activation secretion protein
LGL91_RS15065	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL91_RS15065	COG1902	pentaerythritol trinitrate reductase activity
LGL91_RS15080	COG2963	transposase activity
LGL91_RS15100	COG1451	nucleotide metabolic process
LGL91_RS15105	COG0673	inositol 2-dehydrogenase activity
LGL91_RS15110	COG0861	Integral membrane protein TerC family
LGL91_RS15115	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL91_RS15125	COG2721	sulfolactate sulfo-lyase activity
LGL91_RS15140	COG2271	Major facilitator Superfamily
LGL91_RS15155	COG0586	Pfam SNARE associated Golgi protein
LGL91_RS15170	COG4575	ribosome binding
LGL91_RS15175	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL91_RS15185	COG2259	Doxx family
LGL91_RS15190	COG0583	DNA-binding transcription factor activity
LGL91_RS15195	COG1741	Belongs to the pirin family
LGL91_RS15210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL91_RS15225	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL91_RS15230	COG2823	Periplasmic or secreted lipoprotein
LGL91_RS15235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL91_RS15240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL91_RS15245	COG5002	protein histidine kinase activity
LGL91_RS15245	COG0784	Response regulator, receiver
LGL91_RS15245	COG2198	Histidine kinase
LGL91_RS15255	COG1242	4 iron, 4 sulfur cluster binding
LGL91_RS15260	COG0070	glutamate synthase
LGL91_RS15260	COG0069	glutamate synthase activity
LGL91_RS15260	COG0067	glutamate synthase
LGL91_RS15265	COG0493	'glutamate synthase
LGL91_RS15275	COG2969	positive regulation of protein catabolic process
LGL91_RS15280	COG0625	glutathione transferase activity
LGL91_RS15285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL91_RS15290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL91_RS15295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL91_RS15300	COG3105	Protein conserved in bacteria
LGL91_RS15305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL91_RS15315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL91_RS15320	COG5007	Belongs to the BolA IbaG family
LGL91_RS15325	COG3113	response to antibiotic
LGL91_RS15330	COG2854	intermembrane phospholipid transfer
LGL91_RS15335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL91_RS15340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL91_RS15345	COG1127	ABC transporter
LGL91_RS15350	COG0530	calcium, potassium:sodium antiporter activity
LGL91_RS15355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL91_RS15355	COG0517	IMP dehydrogenase activity
LGL91_RS15360	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL91_RS15365	COG3117	lipopolysaccharide transmembrane transporter activity
LGL91_RS15370	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL91_RS15375	COG1137	ATPase activity
LGL91_RS15380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL91_RS15400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_RS15405	COG0540	Belongs to the ATCase OTCase family
LGL91_RS15410	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL91_RS15420	COG0366	Alpha amylase catalytic
LGL91_RS15425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_RS15425	COG1263	PTS System
LGL91_RS15435	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL91_RS15445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL91_RS15450	COG3783	Cytochrome b(562)
LGL91_RS15455	COG0312	modulator of DNA gyrase
LGL91_RS15460	COG3028	Belongs to the UPF0307 family
LGL91_RS15465	COG2732	(Barnase) inhibitor
LGL91_RS15470	COG4290	ribonuclease
LGL91_RS15480	COG1289	transmembrane transporter activity
LGL91_RS15485	COG1566	PFAM secretion protein HlyD family protein
LGL91_RS15495	COG0583	DNA-binding transcription factor activity
LGL91_RS15500	COG0312	modulator of DNA gyrase
LGL91_RS15505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL91_RS15510	COG3164	Protein of unknown function
LGL91_RS15520	COG0424	maF-like protein
LGL91_RS15525	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL91_RS15530	COG1792	Involved in formation and maintenance of cell shape
LGL91_RS15535	COG1077	Cell shape determining protein MreB Mrl
LGL91_RS15540	COG2200	EAL domain
LGL91_RS15540	COG2199	diguanylate cyclase activity
LGL91_RS15545	COG0604	alcohol dehydrogenase
LGL91_RS15550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL91_RS15555	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL91_RS15565	COG0511	ligase activity, forming carbon-carbon bonds
LGL91_RS15570	COG0439	Biotin carboxylase
LGL91_RS15575	COG3924	membrane
LGL91_RS15580	COG4145	pantothenate transmembrane transporter activity
LGL91_RS15585	COG2264	protein methyltransferase activity
LGL91_RS15590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL91_RS15595	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL91_RS15605	COG1560	Kdo2-lipid A biosynthetic process
LGL91_RS15615	COG1346	cytolysis
LGL91_RS15620	COG1380	Effector of murein hydrolase LrgA
LGL91_RS15625	COG0583	DNA-binding transcription factor activity
LGL91_RS15630	COG0025	NhaP-type Na H and K H
LGL91_RS15635	COG2252	PERMEase
LGL91_RS15650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL91_RS15655	COG2315	Protein conserved in bacteria
LGL91_RS15660	COG1448	Aminotransferase
LGL91_RS15675	COG0604	alcohol dehydrogenase
LGL91_RS15685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL91_RS15690	COG0735	belongs to the Fur family
LGL91_RS15695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL91_RS15700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL91_RS15705	COG2937	Belongs to the GPAT DAPAT family
LGL91_RS15725	COG4580	involved in the transport of maltose and maltodextrins
LGL91_RS15740	COG2182	Extracellular solute-binding protein
LGL91_RS15745	COG1175	transmembrane transport
LGL91_RS15750	COG3833	ABC-type maltose transport systems, permease component
LGL91_RS15755	COG3223	Belongs to the PsiE family
LGL91_RS15765	COG0527	aspartate kinase activity
LGL91_RS15805	COG1222	aaa ATPase
LGL91_RS15885	COG0583	DNA-binding transcription factor activity
LGL91_RS15920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL91_RS15960	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL91_RS15965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL91_RS15970	COG1739	Uncharacterized protein family UPF0029
LGL91_RS15980	COG1024	Enoyl-CoA hydratase
LGL91_RS15980	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL91_RS15990	COG0543	2 iron, 2 sulfur cluster binding
LGL91_RS16005	COG0250	Participates in transcription elongation, termination and antitermination
LGL91_RS16020	COG0805	protein transport
LGL91_RS16025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL91_RS16030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL91_RS16035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL91_RS16040	COG3165	ubiquinone biosynthetic process from chorismate
LGL91_RS16045	COG2226	methyltransferase
LGL91_RS16050	COG1322	Protein conserved in bacteria
LGL91_RS16055	COG0586	Pfam SNARE associated Golgi protein
LGL91_RS16060	COG1966	Carbon starvation protein
LGL91_RS16075	COG0412	Dienelactone hydrolase
LGL91_RS16080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL91_RS16085	COG0583	DNA-binding transcription factor activity
LGL91_RS16090	COG0697	spore germination
LGL91_RS16100	COG0584	glycerophosphoryl diester phosphodiesterase
LGL91_RS16110	COG0395	ABC-type sugar transport system, permease component
LGL91_RS16115	COG1175	transmembrane transport
LGL91_RS16120	COG1653	transport
LGL91_RS16155	COG0410	ABC transporter
LGL91_RS16165	COG4177	L-phenylalanine transmembrane transporter activity
LGL91_RS16185	COG1929	Belongs to the glycerate kinase type-1 family
LGL91_RS16190	COG2610	gluconate transmembrane transporter activity
LGL91_RS16195	COG3835	regulator
LGL91_RS16205	COG2177	Part of the ABC transporter FtsEX involved in
LGL91_RS16210	COG2884	Cell division ATP-binding protein ftsE
LGL91_RS16215	COG0552	protein localization to endoplasmic reticulum
LGL91_RS16215	COG0552	protein localization to endoplasmic reticulum
LGL91_RS16220	COG0742	ribosomal rna small subunit methyltransferase
LGL91_RS16225	COG3776	membrane
LGL91_RS16240	COG3714	YhhN family
LGL91_RS16255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL91_RS16265	COG0247	lactate metabolic process
LGL91_RS16275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL91_RS16285	COG2271	Major facilitator Superfamily
LGL91_RS16290	COG0584	glycerophosphoryl diester phosphodiesterase
LGL91_RS16295	COG0561	phosphatase activity
LGL91_RS16300	COG2267	carboxylic ester hydrolase activity
LGL91_RS16305	COG1280	lysine exporter protein (LysE YggA)
LGL91_RS16310	COG0514	ATP-dependent DNA helicase (RecQ)
LGL91_RS16315	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL91_RS16320	COG2050	protein possibly involved in aromatic compounds catabolism
LGL91_RS16340	COG5564	TIM-barrel signal transduction protein
LGL91_RS16345	COG5441	Belongs to the UPF0261 family
LGL91_RS16355	COG0210	DNA helicase
LGL91_RS16365	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL91_RS16370	COG3159	Protein conserved in bacteria
LGL91_RS16375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL91_RS16380	COG5567	small periplasmic lipoprotein
LGL91_RS16390	COG3072	Adenylate cyclase
LGL91_RS16395	COG0181	hydroxymethylbilane synthase activity
LGL91_RS16400	COG1587	Uroporphyrinogen-III synthase
LGL91_RS16405	COG2959	enzyme of heme biosynthesis
LGL91_RS16410	COG3071	HemY protein
LGL91_RS16460	COG2244	polysaccharide biosynthetic process
LGL91_RS16465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL91_RS16470	COG0456	acetyltransferase
LGL91_RS16475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL91_RS16480	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL91_RS16485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL91_RS16490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL91_RS16495	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL91_RS16500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL91_RS16505	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL91_RS16510	COG3118	belongs to the thioredoxin family
LGL91_RS16520	COG0248	Ppx GppA phosphatase
LGL91_RS16530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL91_RS16545	COG3397	chitin binding
LGL91_RS16555	COG0129	dihydroxy-acid dehydratase activity
LGL91_RS16565	COG3978	acetolactate synthase activity
LGL91_RS16585	COG3085	chromosome segregation
LGL91_RS16590	COG0583	DNA-binding transcription factor activity
LGL91_RS16670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL91_RS16680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL91_RS16680	COG0678	peroxiredoxin activity
LGL91_RS16685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL91_RS16725	COG0165	Argininosuccinate lyase
LGL91_RS16730	COG0137	argininosuccinate synthase activity
LGL91_RS16735	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL91_RS16785	COG0527	aspartate kinase activity
LGL91_RS16785	COG0460	homoserine dehydrogenase
LGL91_RS16790	COG0626	cystathionine gamma-synthase activity
LGL91_RS16795	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL91_RS16805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL91_RS16810	COG1609	Transcriptional regulator
LGL91_RS16815	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL91_RS16820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL91_RS16825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL91_RS16830	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL91_RS16835	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL91_RS16840	COG3074	FtsZ-dependent cytokinesis
LGL91_RS16845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL91_RS16850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL91_RS16855	COG1494	fructose-1,6-bisphosphatase
LGL91_RS16860	COG2814	Major facilitator Superfamily
LGL91_RS16870	COG3152	Membrane
LGL91_RS16885	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL91_RS16895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL91_RS16900	COG3678	ATP-independent chaperone mediated protein folding
LGL91_RS16905	COG0745	RESPONSE REGULATOR receiver
LGL91_RS16910	COG2205	protein histidine kinase activity
LGL91_RS16915	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL91_RS16920	COG1045	serine acetyltransferase
LGL91_RS16925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL91_RS16930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL91_RS16935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL91_RS16940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL91_RS16945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL91_RS16950	COG4942	peptidase
LGL91_RS16955	COG2861	carbohydrate metabolic process
LGL91_RS16970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_RS16975	COG0859	PFAM glycosyl transferase family 9
LGL91_RS16980	COG0859	PFAM glycosyl transferase family 9
LGL91_RS16985	COG1519	Transferase
LGL91_RS17005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL91_RS17010	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL91_RS17015	COG2003	Belongs to the UPF0758 family
LGL91_RS17020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL91_RS17025	COG0756	dUTP diphosphatase activity
LGL91_RS17030	COG1309	transcriptional regulator
LGL91_RS17035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL91_RS17040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL91_RS17045	COG1561	YicC-like family, N-terminal region
LGL91_RS17095	COG5001	Diguanylate cyclase
LGL91_RS17100	COG1024	Enoyl-CoA hydratase
LGL91_RS17105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL91_RS17115	COG2860	membrane
LGL91_RS17120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL91_RS17130	COG1758	RNA polymerase activity
LGL91_RS17135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL91_RS17140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL91_RS17145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL91_RS17150	COG0786	glutamate:sodium symporter activity
LGL91_RS17155	COG2233	PERMEase
LGL91_RS17160	COG2982	Protein involved in outer membrane biogenesis
LGL91_RS17165	COG0456	acetyltransferase
LGL91_RS17180	COG1011	Hydrolase
LGL91_RS17195	COG3852	Histidine kinase
LGL91_RS17205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL91_RS17215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL91_RS17220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL91_RS17220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL91_RS17225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL91_RS17230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL91_RS17235	COG3084	Protein conserved in bacteria
LGL91_RS17245	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL91_RS17270	COG2186	Transcriptional regulator
LGL91_RS17275	COG1609	Transcriptional regulator
LGL91_RS17280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL91_RS17290	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL91_RS17295	COG1129	ABC transporter
LGL91_RS17300	COG1869	D-ribose catabolic process
LGL91_RS17305	COG3158	transport of potassium into the cell
LGL91_RS17310	COG0714	Associated with various cellular activities
LGL91_RS17315	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL91_RS17325	COG2502	aspartate--ammonia ligase
LGL91_RS17330	COG1522	sequence-specific DNA binding
LGL91_RS17335	COG0716	FMN binding
LGL91_RS17340	COG0445	tRNA wobble uridine modification
LGL91_RS17345	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL91_RS17350	COG3312	ion transport
LGL91_RS17355	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL91_RS17365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL91_RS17375	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL91_RS17380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL91_RS17390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL91_RS17405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL91_RS17410	COG0573	inorganic phosphate transmembrane transporter activity
LGL91_RS17415	COG0581	inorganic phosphate transmembrane transporter activity
LGL91_RS17425	COG0704	Plays a role in the regulation of phosphate uptake
LGL91_RS17430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_RS17435	COG0765	amino acid transport
LGL91_RS17440	COG0765	amino acid transport
LGL91_RS17445	COG2252	PERMEase
LGL91_RS17450	COG0840	transmembrane signaling receptor activity
LGL91_RS17460	COG3121	Chaperone
LGL91_RS17475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL91_RS17480	COG0706	membrane insertase activity
LGL91_RS17490	COG0594	ribonuclease P activity
LGL91_RS17495	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGL91_RS17515	COG5433	transposase activity
LGL91_RS17525	COG3210	domain, Protein
LGL91_RS17530	COG1598	PFAM Uncharacterised protein family UPF0150
LGL91_RS17540	COG1192	Involved in chromosome partitioning
LGL91_RS17550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL91_RS17555	COG0066	3-isopropylmalate dehydratase activity
LGL91_RS17575	COG1192	Involved in chromosome partitioning
LGL91_RS17585	COG3657	addiction module killer protein
LGL91_RS17665	COG1304	FMN binding
LGL91_RS17685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL91_RS17690	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LGL91_RS17770	COG0840	transmembrane signaling receptor activity
LGL91_RS17785	COG3547	Transposase (IS116 IS110 IS902 family)
LGL91_RS17810	COG3657	addiction module killer protein
LGL91_RS17815	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL91_RS17830	COG3210	domain, Protein
LGL91_RS17935	COG3547	Transposase (IS116 IS110 IS902 family)
LGL91_RS17965	COG3718	enzyme involved in inositol metabolism
LGL91_RS17975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL91_RS17980	COG0673	inositol 2-dehydrogenase activity
LGL91_RS17985	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL91_RS17990	COG1129	ABC transporter
LGL91_RS17995	COG1879	ABC-type sugar transport system periplasmic component
LGL91_RS18000	COG0673	inositol 2-dehydrogenase activity
LGL91_RS18005	COG3962	Belongs to the TPP enzyme family
LGL91_RS18060	COG0625	glutathione transferase activity
LGL91_RS18065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL91_RS18230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL91_RS18235	COG2916	Histone family protein nucleoid-structuring protein H-NS
LGL91_RS18305	COG0840	transmembrane signaling receptor activity
LGL91_RS18310	COG0840	transmembrane signaling receptor activity
LGL91_RS18320	COG2200	EAL domain
LGL91_RS18325	COG2200	EAL domain