locus-tag	class	description
LGL85_RS00010	COG0592	DNA-directed DNA polymerase activity
LGL85_RS00020	COG0187	DNA topoisomerase II activity
LGL85_RS00025	COG0561	phosphatase activity
LGL85_RS00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL85_RS00035	COG5645	(Lipo)protein
LGL85_RS00050	COG0569	domain protein
LGL85_RS00050	COG2985	domain, Protein
LGL85_RS00055	COG3977	Valine--pyruvate aminotransferase
LGL85_RS00060	COG2885	chlorophyll binding
LGL85_RS00085	COG2818	Glycosylase
LGL85_RS00135	COG2213	PTS system mannitol-specific
LGL85_RS00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_RS00145	COG3722	fumarate hydratase activity
LGL85_RS00155	COG2258	MOSC domain
LGL85_RS00160	COG0840	transmembrane signaling receptor activity
LGL85_RS00165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL85_RS00180	COG0437	4 iron, 4 sulfur cluster binding
LGL85_RS00185	COG2864	formate dehydrogenase
LGL85_RS00195	COG1921	L-seryl-tRNASec selenium transferase activity
LGL85_RS00200	COG3276	selenocysteine insertion sequence binding
LGL85_RS00205	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL85_RS00215	COG3274	enterobacterial common antigen metabolic process
LGL85_RS00225	COG0582	viral genome integration into host DNA
LGL85_RS00270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL85_RS00275	COG2986	histidine ammonia-lyase
LGL85_RS00295	COG2194	sulfuric ester hydrolase activity
LGL85_RS00300	COG2197	response regulator
LGL85_RS00305	COG3851	Histidine kinase
LGL85_RS00310	COG2271	Major facilitator Superfamily
LGL85_RS00320	COG0747	negative chemotaxis
LGL85_RS00325	COG0601	transmembrane transport
LGL85_RS00330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL85_RS00335	COG0444	Belongs to the ABC transporter superfamily
LGL85_RS00340	COG4608	Belongs to the ABC transporter superfamily
LGL85_RS00345	COG2194	sulfuric ester hydrolase activity
LGL85_RS00370	COG1215	transferase activity, transferring glycosyl groups
LGL85_RS00375	COG1215	transferase activity, transferring glycosyl groups
LGL85_RS00380	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL85_RS00385	COG3118	belongs to the thioredoxin family
LGL85_RS00385	COG0457	Tetratricopeptide repeat
LGL85_RS00390	COG2199	diguanylate cyclase activity
LGL85_RS00390	COG2200	EAL domain
LGL85_RS00395	COG1301	dicarboxylic acid transport
LGL85_RS00400	COG0612	Peptidase, M16
LGL85_RS00405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL85_RS00410	COG1942	4-Oxalocrotonate Tautomerase
LGL85_RS00415	COG2200	EAL domain
LGL85_RS00420	COG2134	cdp-diacylglycerol pyrophosphatase
LGL85_RS00425	COG1295	ribonuclease BN
LGL85_RS00435	COG1301	dicarboxylic acid transport
LGL85_RS00440	COG0626	cystathionine gamma-synthase activity
LGL85_RS00455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL85_RS00460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL85_RS00465	COG0339	signal peptide processing
LGL85_RS00470	COG0742	ribosomal rna small subunit methyltransferase
LGL85_RS00480	COG0589	response to stress
LGL85_RS00490	COG0306	phosphate transporter
LGL85_RS00495	COG2081	HI0933 family
LGL85_RS00505	COG1247	-acetyltransferase
LGL85_RS00515	COG1741	Belongs to the pirin family
LGL85_RS00520	COG1609	Transcriptional regulator
LGL85_RS00530	COG3265	gluconokinase activity
LGL85_RS00535	COG2095	MarC family integral membrane protein
LGL85_RS00540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL85_RS00545	COG3275	phosphorelay sensor kinase activity
LGL85_RS00550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL85_RS00555	COG1523	belongs to the glycosyl hydrolase 13 family
LGL85_RS00560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL85_RS00565	COG0297	glycogen (starch) synthase activity
LGL85_RS00570	COG0058	SHG alpha-glucan phosphorylase activity
LGL85_RS00575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL85_RS00580	COG1349	DNA-binding transcription factor activity
LGL85_RS00585	COG0705	Rhomboid family
LGL85_RS00595	COG2909	trisaccharide binding
LGL85_RS00600	COG0058	SHG alpha-glucan phosphorylase activity
LGL85_RS00605	COG1640	4-alpha-glucanotransferase
LGL85_RS00615	COG1040	competence protein
LGL85_RS00620	COG0596	Alpha beta hydrolase
LGL85_RS00640	COG1918	ferrous iron import across plasma membrane
LGL85_RS00645	COG2183	response to ionizing radiation
LGL85_RS00670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL85_RS00685	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL85_RS00695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL85_RS00700	COG1011	Hydrolase
LGL85_RS00710	COG0494	nUDIX hydrolase
LGL85_RS00715	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL85_RS00740	COG4796	Type ii and iii secretion system protein
LGL85_RS00745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL85_RS00765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL85_RS00775	COG0180	Tryptophanyl-tRNA synthetase
LGL85_RS00795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL85_RS00800	COG0402	S-adenosylhomocysteine deaminase activity
LGL85_RS00805	COG0738	Major facilitator superfamily
LGL85_RS00820	COG1609	Transcriptional regulator
LGL85_RS00825	COG1486	melibiose metabolic process
LGL85_RS00830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL85_RS00845	COG1289	transmembrane transporter activity
LGL85_RS00850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL85_RS00855	COG1765	OsmC-like protein
LGL85_RS00880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL85_RS00885	COG3954	Phosphoribulokinase
LGL85_RS00895	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL85_RS00905	COG0859	PFAM glycosyl transferase family 9
LGL85_RS00910	COG1216	Glycosyl transferase, family 2
LGL85_RS00915	COG0488	(ABC) transporter
LGL85_RS00920	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL85_RS00930	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL85_RS00935	COG1047	Peptidyl-prolyl cis-trans
LGL85_RS00945	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL85_RS00950	COG2964	Protein conserved in bacteria
LGL85_RS00960	COG2923	Belongs to the DsrF TusC family
LGL85_RS00965	COG2168	tRNA wobble position uridine thiolation
LGL85_RS00970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL85_RS00975	COG0049	tRNA binding
LGL85_RS00985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL85_RS01000	COG0051	transcription antitermination factor activity, RNA binding
LGL85_RS01005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL85_RS01015	COG0089	rRNA binding
LGL85_RS01020	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL85_RS01025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL85_RS01030	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL85_RS01040	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL85_RS01045	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL85_RS01050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL85_RS01055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL85_RS01065	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL85_RS01090	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL85_RS01095	COG1841	ribosomal large subunit assembly
LGL85_RS01100	COG0200	Binds to the 23S rRNA
LGL85_RS01105	COG0201	protein transport
LGL85_RS01110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL85_RS01115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL85_RS01125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL85_RS01135	COG0203	ribosomal protein L17
LGL85_RS01140	COG0789	Transcriptional regulator
LGL85_RS01145	COG3036	rescue of stalled ribosome
LGL85_RS01150	COG1970	mechanosensitive ion channel activity
LGL85_RS01160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL85_RS01160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL85_RS01165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL85_RS01170	COG0242	peptide deformylase activity
LGL85_RS01175	COG0758	DNA mediated transformation
LGL85_RS01180	COG2922	Belongs to the Smg family
LGL85_RS01185	COG0551	DNA topoisomerase type I activity
LGL85_RS01190	COG0009	L-threonylcarbamoyladenylate synthase
LGL85_RS01200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL85_RS01225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL85_RS01230	COG3162	membrane
LGL85_RS01235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL85_RS01240	COG1301	dicarboxylic acid transport
LGL85_RS01250	COG2391	methyltransferase activity
LGL85_RS01255	COG0425	Belongs to the sulfur carrier protein TusA family
LGL85_RS01260	COG1086	Polysaccharide biosynthesis protein
LGL85_RS01265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL85_RS01270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL85_RS01275	COG2089	acid synthase
LGL85_RS01295	COG1083	cytidylyl-transferase
LGL85_RS01295	COG2755	lipolytic protein G-D-S-L family
LGL85_RS01300	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_RS01320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL85_RS01320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL85_RS01325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGL85_RS01345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL85_RS01365	COG1309	transcriptional regulator
LGL85_RS01375	COG4232	protein-disulfide reductase activity
LGL85_RS01385	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL85_RS01415	COG1509	lysine 2,3-aminomutase activity
LGL85_RS01425	COG3397	chitin binding
LGL85_RS01445	COG3188	usher protein
LGL85_RS01465	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL85_RS01470	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL85_RS01475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL85_RS01480	COG1053	succinate dehydrogenase
LGL85_RS01485	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL85_RS01490	COG3264	Mechanosensitive ion channel
LGL85_RS01490	COG1511	domain protein
LGL85_RS01495	COG0688	phosphatidylethanolamine metabolic process
LGL85_RS01500	COG1162	GTPase activity
LGL85_RS01505	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL85_RS01525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL85_RS01530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL85_RS01530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL85_RS01535	COG0802	atpase or kinase
LGL85_RS01540	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL85_RS01550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL85_RS01560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL85_RS01565	COG0330	HflC and HflK could
LGL85_RS01570	COG0330	HflC and HflK could
LGL85_RS01575	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL85_RS01580	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL85_RS01585	COG1959	2 iron, 2 sulfur cluster binding
LGL85_RS01590	COG0557	exoribonuclease II activity
LGL85_RS01595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL85_RS01615	COG3121	Chaperone
LGL85_RS01620	COG3188	usher protein
LGL85_RS01640	COG1073	alpha beta
LGL85_RS01650	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL85_RS01655	COG2965	DNA replication, synthesis of RNA primer
LGL85_RS01660	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL85_RS01665	COG0359	binds to the 23S rRNA
LGL85_RS01670	COG3061	Opacity-associated protein A
LGL85_RS01675	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL85_RS01685	COG0737	Belongs to the 5'-nucleotidase family
LGL85_RS01690	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL85_RS01695	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL85_RS01705	COG1253	flavin adenine dinucleotide binding
LGL85_RS01710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL85_RS01715	COG0729	surface antigen
LGL85_RS01720	COG2911	Protein conserved in bacteria
LGL85_RS01725	COG2105	PFAM AIG2 family protein
LGL85_RS01730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL85_RS01740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL85_RS01755	COG3423	Transcriptional regulator
LGL85_RS01770	COG0142	geranyltranstransferase activity
LGL85_RS01790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL85_RS01795	COG0642	Histidine kinase
LGL85_RS01800	COG0745	RESPONSE REGULATOR receiver
LGL85_RS01805	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL85_RS01815	COG1534	Rna-binding protein
LGL85_RS01820	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL85_RS01830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL85_RS01835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL85_RS01840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL85_RS01860	COG0195	Participates in both transcription termination and antitermination
LGL85_RS01870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL85_RS01885	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL85_RS01895	COG0513	Belongs to the DEAD box helicase family
LGL85_RS01900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL85_RS01915	COG0826	peptidase U32
LGL85_RS01920	COG0826	peptidase U32
LGL85_RS01925	COG3154	lipid carrier protein
LGL85_RS01930	COG3153	acetyltransferase
LGL85_RS01935	COG2827	Endonuclease containing a URI domain
LGL85_RS01940	COG0531	amino acid
LGL85_RS01945	COG1982	Orn Lys Arg decarboxylase major
LGL85_RS01955	COG3787	Belongs to the UPF0306 family
LGL85_RS01960	COG0702	epimerase
LGL85_RS01965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL85_RS01970	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL85_RS01975	COG3454	Phosphonate metabolism
LGL85_RS01980	COG4778	phosphonate C-P lyase system protein PhnL
LGL85_RS01985	COG4107	phosphonate C-P lyase system protein PhnK
LGL85_RS01990	COG3627	carbon phosphorus lyase activity
LGL85_RS01995	COG3626	phosphonate metabolism
LGL85_RS02000	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL85_RS02005	COG3624	Phosphonate C-P lyase system protein PhnG
LGL85_RS02025	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL85_RS02040	COG2927	DNA polymerase III (CHI subunit)
LGL85_RS02045	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL85_RS02050	COG0795	lipopolysaccharide-transporting ATPase activity
LGL85_RS02055	COG0795	lipopolysaccharide-transporting ATPase activity
LGL85_RS02095	COG5492	domain, Protein
LGL85_RS02115	COG3119	arylsulfatase activity
LGL85_RS02120	COG1349	DNA-binding transcription factor activity
LGL85_RS02130	COG2222	sugar isomerase
LGL85_RS02135	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_RS02140	COG3715	PTS system
LGL85_RS02145	COG3716	PTS system mannose fructose sorbose family IID component
LGL85_RS02155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL85_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_RS02175	COG0641	radical SAM
LGL85_RS02180	COG3119	arylsulfatase activity
LGL85_RS02205	COG0859	PFAM glycosyl transferase family 9
LGL85_RS02220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_RS02225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL85_RS02235	COG2376	Dihydroxyacetone kinase
LGL85_RS02240	COG1461	Dihydroxyacetone kinase
LGL85_RS02245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL85_RS02245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_RS02245	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL85_RS02285	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL85_RS02300	COG2823	Periplasmic or secreted lipoprotein
LGL85_RS02310	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL85_RS02315	COG0084	hydrolase, TatD family'
LGL85_RS02320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL85_RS02335	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL85_RS02345	COG3726	membrane protein affecting hemolysin expression
LGL85_RS02350	COG0560	Phosphoserine phosphatase
LGL85_RS02365	COG0488	(ABC) transporter
LGL85_RS02390	COG0741	lytic transglycosylase activity
LGL85_RS02395	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL85_RS02400	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL85_RS02405	COG0406	alpha-ribazole phosphatase activity
LGL85_RS02410	COG2207	Transcriptional regulator
LGL85_RS02410	COG3708	Transcriptional regulator
LGL85_RS02415	COG3045	CreA protein
LGL85_RS02420	COG0745	RESPONSE REGULATOR receiver
LGL85_RS02455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL85_RS02460	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL85_RS02465	COG0477	Major facilitator Superfamily
LGL85_RS02475	COG1584	GPR1 FUN34 yaaH family protein
LGL85_RS02480	COG0443	Heat shock 70 kDa protein
LGL85_RS02490	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL85_RS02495	COG0583	DNA-binding transcription factor activity
LGL85_RS02505	COG0196	riboflavin kinase activity
LGL85_RS02515	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL85_RS02520	COG1047	Peptidyl-prolyl cis-trans
LGL85_RS02525	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL85_RS02540	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL85_RS02550	COG2966	Psort location CytoplasmicMembrane, score
LGL85_RS02575	COG2967	ApaG domain
LGL85_RS02580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL85_RS02585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL85_RS02595	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL85_RS02605	COG0564	pseudouridine synthase activity
LGL85_RS02610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL85_RS02615	COG0417	DNA replication proofreading
LGL85_RS02620	COG0586	Pfam SNARE associated Golgi protein
LGL85_RS02630	COG1178	ABC-type Fe3 transport system permease component
LGL85_RS02635	COG4143	(ABC) transporter
LGL85_RS02650	COG2814	Major facilitator Superfamily
LGL85_RS02660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL85_RS02665	COG0473	3-isopropylmalate dehydrogenase activity
LGL85_RS02680	COG1022	Amp-dependent synthetase and ligase
LGL85_RS02685	COG0028	Belongs to the TPP enzyme family
LGL85_RS02710	COG0275	rRNA processing
LGL85_RS02715	COG3116	cell division
LGL85_RS02720	COG0768	penicillin binding
LGL85_RS02725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL85_RS02730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL85_RS02745	COG0772	Belongs to the SEDS family
LGL85_RS02750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL85_RS02755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL85_RS02770	COG0849	cell division
LGL85_RS02775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL85_RS02800	COG0494	nUDIX hydrolase
LGL85_RS02820	COG0516	GMP reductase activity
LGL85_RS02825	COG1459	type II secretion system
LGL85_RS02830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL85_RS02835	COG4969	Belongs to the N-Me-Phe pilin family
LGL85_RS02850	COG3725	Membrane protein required for beta-lactamase induction
LGL85_RS02855	COG1113	amino acid transport
LGL85_RS02860	COG2186	Transcriptional regulator
LGL85_RS02865	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL85_RS02870	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL85_RS02875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL85_RS02885	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL85_RS02890	COG3112	Uncharacterised protein family (UPF0231)
LGL85_RS02905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL85_RS02915	COG2132	Multicopper oxidase
LGL85_RS02925	COG0288	reversible hydration of carbon dioxide
LGL85_RS02930	COG1131	(ABC) transporter
LGL85_RS02935	COG0842	Transport permease protein
LGL85_RS02940	COG0726	polysaccharide deacetylase
LGL85_RS02945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL85_RS02950	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL85_RS02955	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL85_RS02960	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL85_RS02965	COG0617	tRNA 3'-terminal CCA addition
LGL85_RS02980	COG1489	DNA binding
LGL85_RS02985	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL85_RS02990	COG1643	Atp-dependent helicase
LGL85_RS02995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL85_RS03000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL85_RS03010	COG0316	Belongs to the HesB IscA family
LGL85_RS03015	COG2860	membrane
LGL85_RS03025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL85_RS03030	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL85_RS03035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL85_RS03045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL85_RS03050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL85_RS03055	COG3956	TIGRFAM MazG family protein
LGL85_RS03060	COG0504	CTP synthase activity
LGL85_RS03070	COG0602	queuosine metabolic process
LGL85_RS03075	COG0720	synthase
LGL85_RS03080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL85_RS03090	COG0175	sulfate reduction
LGL85_RS03105	COG2234	aminopeptidase activity
LGL85_RS03110	COG1648	precorrin-2 dehydrogenase activity
LGL85_RS03110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL85_RS03115	COG0175	sulfate reduction
LGL85_RS03120	COG2895	sulfate adenylyltransferase (ATP) activity
LGL85_RS03125	COG0529	Catalyzes the synthesis of activated sulfate
LGL85_RS03135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL85_RS03145	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL85_RS03150	COG0585	pseudouridine synthase activity
LGL85_RS03155	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL85_RS03165	COG4942	peptidase
LGL85_RS03165	COG1388	LysM domain
LGL85_RS03170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL85_RS03175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL85_RS03250	COG2205	protein histidine kinase activity
LGL85_RS03275	COG0741	lytic transglycosylase activity
LGL85_RS03405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL85_RS03425	COG3397	chitin binding
LGL85_RS03435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL85_RS03480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL85_RS03490	COG3031	protein transport across the cell outer membrane
LGL85_RS03515	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL85_RS03515	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL85_RS03530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL85_RS03535	COG2137	regulation of response to DNA damage stimulus
LGL85_RS03540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL85_RS03545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL85_RS03585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL85_RS03590	COG1238	metal cluster binding
LGL85_RS03595	COG2918	glutathione biosynthetic process
LGL85_RS03600	COG1854	S-ribosylhomocysteine lyase activity
LGL85_RS03605	COG4536	flavin adenine dinucleotide binding
LGL85_RS03610	COG4137	Cytochrome C assembly protein
LGL85_RS03615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL85_RS03625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL85_RS03630	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL85_RS03635	COG0335	large ribosomal subunit rRNA binding
LGL85_RS03640	COG3137	Salt-induced outer membrane protein
LGL85_RS03645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL85_RS03650	COG3279	Response regulator of the LytR AlgR family
LGL85_RS03655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL85_RS03660	COG1605	Chorismate mutase
LGL85_RS03660	COG0287	Prephenate dehydrogenase
LGL85_RS03665	COG1605	Chorismate mutase
LGL85_RS03665	COG0077	Prephenate dehydratase
LGL85_RS03675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL85_RS03680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL85_RS03685	COG0564	pseudouridine synthase activity
LGL85_RS03690	COG1496	oxidoreductase activity
LGL85_RS03695	COG0542	response to heat
LGL85_RS03730	COG3021	interspecies interaction between organisms
LGL85_RS03735	COG0741	lytic transglycosylase activity
LGL85_RS03735	COG1388	LysM domain
LGL85_RS03745	COG2226	methyltransferase
LGL85_RS03755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL85_RS03765	COG1960	acyl-CoA dehydrogenase activity
LGL85_RS03770	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL85_RS03775	COG0121	glutamine amidotransferase
LGL85_RS03780	COG3034	peptidoglycan biosynthetic process
LGL85_RS03790	COG1805	sodium ion transport
LGL85_RS03795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL85_RS03800	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL85_RS03805	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL85_RS03815	COG1477	protein flavinylation
LGL85_RS03820	COG2991	Protein conserved in bacteria
LGL85_RS03830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL85_RS03835	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL85_RS03840	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL85_RS03845	COG1073	alpha beta
LGL85_RS03860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL85_RS03895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL85_RS03920	COG4126	flavin adenine dinucleotide binding
LGL85_RS03930	COG2974	May be involved in recombination
LGL85_RS03935	COG1940	carbohydrate kinase activity
LGL85_RS03940	COG0419	ATPase involved in DNA repair
LGL85_RS03945	COG0420	3'-5' exonuclease activity
LGL85_RS03950	COG0745	RESPONSE REGULATOR receiver
LGL85_RS03955	COG5002	protein histidine kinase activity
LGL85_RS03970	COG1113	amino acid transport
LGL85_RS03975	COG0366	Alpha amylase catalytic
LGL85_RS03980	COG0300	oxidoreductase activity
LGL85_RS03985	COG0450	alkyl hydroperoxide reductase
LGL85_RS03990	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL85_RS04005	COG1862	Preprotein translocase
LGL85_RS04010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL85_RS04015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL85_RS04020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL85_RS04025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL85_RS04025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL85_RS04030	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL85_RS04040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL85_RS04045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL85_RS04050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL85_RS04055	COG0142	geranyltranstransferase activity
LGL85_RS04090	COG0693	protein deglycase activity
LGL85_RS04095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL85_RS04100	COG1666	GTP binding
LGL85_RS04105	COG2814	Major facilitator Superfamily
LGL85_RS04115	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL85_RS04120	COG1845	cytochrome c oxidase, subunit III
LGL85_RS04125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL85_RS04130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL85_RS04140	COG2223	nitrite transmembrane transporter activity
LGL85_RS04145	COG3056	Lipoprotein
LGL85_RS04150	COG0271	Belongs to the BolA IbaG family
LGL85_RS04160	COG0740	serine-type endopeptidase activity
LGL85_RS04165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL85_RS04170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL85_RS04175	COG0776	regulation of translation
LGL85_RS04180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL85_RS04185	COG1555	photosystem II stabilization
LGL85_RS04190	COG0824	Thioesterase
LGL85_RS04195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL85_RS04200	COG4533	DNA binding
LGL85_RS04215	COG1522	sequence-specific DNA binding
LGL85_RS04220	COG1132	(ABC) transporter
LGL85_RS04225	COG1132	(ABC) transporter
LGL85_RS04230	COG0347	Belongs to the P(II) protein family
LGL85_RS04240	COG1946	Acyl-CoA thioesterase
LGL85_RS04245	COG3695	enzyme binding
LGL85_RS04270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL85_RS04275	COG0254	rRNA binding
LGL85_RS04280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL85_RS04285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_RS04290	COG1309	transcriptional regulator
LGL85_RS04295	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL85_RS04300	COG1196	nuclear chromosome segregation
LGL85_RS04300	COG3264	Mechanosensitive ion channel
LGL85_RS04315	COG2832	Protein of unknown function (DUF454)
LGL85_RS04320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL85_RS04360	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL85_RS04365	COG0326	Molecular chaperone. Has ATPase activity
LGL85_RS04380	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL85_RS04385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL85_RS04390	COG4651	solute:proton antiporter activity
LGL85_RS04390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL85_RS04395	COG0737	Belongs to the 5'-nucleotidase family
LGL85_RS04400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL85_RS04405	COG3735	TraB family
LGL85_RS04410	COG2217	Heavy metal translocating P-type atpase
LGL85_RS04415	COG0789	Transcriptional regulator
LGL85_RS04420	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL85_RS04425	COG0330	HflC and HflK could
LGL85_RS04430	COG3118	belongs to the thioredoxin family
LGL85_RS04435	COG0300	oxidoreductase activity
LGL85_RS04440	COG2755	lipolytic protein G-D-S-L family
LGL85_RS04445	COG4181	ATPase activity
LGL85_RS04450	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL85_RS04455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL85_RS04460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL85_RS04465	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL85_RS04470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL85_RS04500	COG3188	usher protein
LGL85_RS04505	COG3121	Chaperone
LGL85_RS04535	COG2501	S4 domain
LGL85_RS04540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL85_RS04555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL85_RS04560	COG1393	Belongs to the ArsC family
LGL85_RS04570	COG1022	Amp-dependent synthetase and ligase
LGL85_RS04595	COG3038	cytochrome b561
LGL85_RS04625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL85_RS04635	COG1215	transferase activity, transferring glycosyl groups
LGL85_RS04655	COG3250	beta-galactosidase activity
LGL85_RS04670	COG1309	transcriptional regulator
LGL85_RS04700	COG2197	response regulator
LGL85_RS04705	COG1278	Cold shock
LGL85_RS04725	COG3706	GGDEF domain
LGL85_RS04735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL85_RS04745	COG2921	Belongs to the UPF0250 family
LGL85_RS04750	COG1686	Belongs to the peptidase S11 family
LGL85_RS04755	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL85_RS04760	COG0772	Belongs to the SEDS family
LGL85_RS04765	COG0768	penicillin binding
LGL85_RS04770	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL85_RS04775	COG0799	negative regulation of ribosome biogenesis
LGL85_RS04780	COG0582	viral genome integration into host DNA
LGL85_RS04895	COG0305	Participates in initiation and elongation during chromosome replication
LGL85_RS04945	COG3646	Phage regulatory protein
LGL85_RS04970	COG3567	Phage-associated protein, HI1409 family
LGL85_RS04975	COG2369	cell adhesion
LGL85_RS05105	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL85_RS05115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL85_RS05120	COG1466	dna polymerase III delta subunit
LGL85_RS05125	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL85_RS05135	COG2888	peptidyl-tyrosine sulfation
LGL85_RS05140	COG1126	abc transporter atp-binding protein
LGL85_RS05145	COG0765	amino acid transport
LGL85_RS05150	COG0765	amino acid transport
LGL85_RS05160	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL85_RS05165	COG4535	Mg2 and Co2 transporter CorC
LGL85_RS05170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL85_RS05175	COG1702	phosphate starvation-inducible protein PhoH
LGL85_RS05180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL85_RS05185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL85_RS05220	COG0367	asparagine synthase
LGL85_RS05225	COG0647	UMP catabolic process
LGL85_RS05230	COG1940	carbohydrate kinase activity
LGL85_RS05230	COG1846	Transcriptional regulator
LGL85_RS05235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL85_RS05245	COG1263	PTS System
LGL85_RS05245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_RS05245	COG2190	(PTS) system
LGL85_RS05270	COG0735	belongs to the Fur family
LGL85_RS05280	COG0840	transmembrane signaling receptor activity
LGL85_RS05290	COG0596	Alpha beta hydrolase
LGL85_RS05295	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL85_RS05300	COG0033	Phosphoglucomutase
LGL85_RS05310	COG0745	RESPONSE REGULATOR receiver
LGL85_RS05315	COG2205	protein histidine kinase activity
LGL85_RS05320	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL85_RS05325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL85_RS05345	COG3272	Protein of unknown function (DUF1722)
LGL85_RS05350	COG0415	Belongs to the DNA photolyase family
LGL85_RS05355	COG5212	phosphodiesterase
LGL85_RS05360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL85_RS05365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL85_RS05370	COG1984	allophanate hydrolase subunit 2
LGL85_RS05375	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL85_RS05410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL85_RS05415	COG1053	succinate dehydrogenase
LGL85_RS05420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL85_RS05425	COG0567	Dehydrogenase, E1 component
LGL85_RS05430	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL85_RS05435	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL85_RS05440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL85_RS05445	COG0737	Belongs to the 5'-nucleotidase family
LGL85_RS05450	COG1271	oxidase subunit
LGL85_RS05455	COG1294	oxidase, subunit
LGL85_RS05460	COG4890	Cyd operon protein YbgT
LGL85_RS05465	COG3790	cyd operon protein YbgE
LGL85_RS05470	COG0824	Thioesterase
LGL85_RS05475	COG0811	peptide transport
LGL85_RS05480	COG0848	biopolymer transport protein
LGL85_RS05485	COG3064	Membrane
LGL85_RS05485	COG3064	Membrane
LGL85_RS05490	COG0823	Involved in the tonB-independent uptake of proteins
LGL85_RS05495	COG2885	chlorophyll binding
LGL85_RS05500	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL85_RS05540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL85_RS05550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_RS05550	COG2205	protein histidine kinase activity
LGL85_RS05560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL85_RS05565	COG0588	phosphoglycerate mutase activity
LGL85_RS05575	COG2017	converts alpha-aldose to the beta-anomer
LGL85_RS05585	COG1085	galactose-1-phosphate uridylyltransferase
LGL85_RS05590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL85_RS05605	COG2005	Transcriptional regulator
LGL85_RS05605	COG3585	molybdate ion transport
LGL85_RS05615	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL85_RS05620	COG4149	molybdate abc transporter
LGL85_RS05630	COG0561	phosphatase activity
LGL85_RS05635	COG2706	6-phosphogluconolactonase activity
LGL85_RS05650	COG0156	8-amino-7-oxononanoate synthase activity
LGL85_RS05655	COG2226	methyltransferase
LGL85_RS05670	COG0556	nucleotide-excision repair
LGL85_RS05675	COG4628	conserved protein (DUF2132)
LGL85_RS05690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_RS05695	COG1120	ATPase activity
LGL85_RS05700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL85_RS05705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL85_RS05715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL85_RS05720	COG0314	molybdopterin synthase activity
LGL85_RS05725	COG0670	Belongs to the BI1 family
LGL85_RS05730	COG0842	Transport permease protein
LGL85_RS05735	COG0842	Transport permease protein
LGL85_RS05740	COG1131	(ABC) transporter
LGL85_RS05745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_RS05750	COG1309	transcriptional regulator
LGL85_RS05755	COG0513	Belongs to the DEAD box helicase family
LGL85_RS05760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL85_RS05770	COG1686	Belongs to the peptidase S11 family
LGL85_RS05775	COG0277	FAD linked oxidase domain protein
LGL85_RS05795	COG2261	transglycosylase associated protein
LGL85_RS05805	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL85_RS05815	COG3639	organic phosphonate transmembrane transporter activity
LGL85_RS05820	COG4807	Protein conserved in bacteria
LGL85_RS05825	COG2897	thiosulfate sulfurtransferase activity
LGL85_RS05830	COG1732	Glycine betaine
LGL85_RS05835	COG1174	glycine betaine transport
LGL85_RS05840	COG1125	glycine betaine transport
LGL85_RS05845	COG1174	glycine betaine transport
LGL85_RS05850	COG0531	amino acid
LGL85_RS05855	COG1982	Orn Lys Arg decarboxylase major
LGL85_RS05865	COG0697	spore germination
LGL85_RS05880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL85_RS05885	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL85_RS05890	COG1126	abc transporter atp-binding protein
LGL85_RS05895	COG0765	amino acid transport
LGL85_RS05900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_RS05920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL85_RS05925	COG2239	Acts as a magnesium transporter
LGL85_RS05930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL85_RS05935	COG0488	(ABC) transporter
LGL85_RS05940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL85_RS05945	COG0303	'Molybdopterin
LGL85_RS05965	COG0583	DNA-binding transcription factor activity
LGL85_RS05970	COG0477	Major facilitator Superfamily
LGL85_RS05975	COG0302	gtp cyclohydrolase
LGL85_RS05980	COG2311	Membrane
LGL85_RS06005	COG2949	membrane
LGL85_RS06010	COG0281	malic enzyme
LGL85_RS06020	COG0583	DNA-binding transcription factor activity
LGL85_RS06030	COG1346	cytolysis
LGL85_RS06035	COG1380	Effector of murein hydrolase LrgA
LGL85_RS06045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL85_RS06045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL85_RS06050	COG0489	protein tyrosine kinase activity
LGL85_RS06055	COG0572	uridine kinase
LGL85_RS06060	COG0717	Belongs to the dCTP deaminase family
LGL85_RS06065	COG2982	Protein involved in outer membrane biogenesis
LGL85_RS06070	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL85_RS06075	COG1253	flavin adenine dinucleotide binding
LGL85_RS06080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL85_RS06085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL85_RS06090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL85_RS06100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL85_RS06100	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL85_RS06110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL85_RS06120	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL85_RS06120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL85_RS06125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL85_RS06130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL85_RS06145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL85_RS06150	COG0625	glutathione transferase activity
LGL85_RS06165	COG0626	cystathionine gamma-synthase activity
LGL85_RS06175	COG1686	Belongs to the peptidase S11 family
LGL85_RS06180	COG1760	l-serine dehydratase
LGL85_RS06185	COG0814	amino acid
LGL85_RS06190	COG1349	DNA-binding transcription factor activity
LGL85_RS06200	COG0671	phosphoesterase, PA-phosphatase related
LGL85_RS06210	COG0569	domain protein
LGL85_RS06210	COG2985	domain, Protein
LGL85_RS06230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL85_RS06235	COG3842	ATPase activity
LGL85_RS06240	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL85_RS06245	COG1177	transmembrane transport
LGL85_RS06260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_RS06265	COG4160	amino acid transport
LGL85_RS06270	COG4215	(ABC) transporter
LGL85_RS06275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_RS06280	COG1126	abc transporter atp-binding protein
LGL85_RS06290	COG0393	Putative heavy-metal-binding
LGL85_RS06295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL85_RS06300	COG0702	epimerase
LGL85_RS06305	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL85_RS06310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL85_RS06315	COG1151	hydroxylamine reductase activity
LGL85_RS06320	COG2431	L-lysine efflux transmembrane transporter activity
LGL85_RS06325	COG3593	DNA synthesis involved in DNA repair
LGL85_RS06330	COG2990	Protein conserved in bacteria
LGL85_RS06335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_RS06345	COG1278	Cold shock
LGL85_RS06350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL85_RS06355	COG0542	response to heat
LGL85_RS06360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL85_RS06370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL85_RS06380	COG0492	ferredoxin-NADP+ reductase activity
LGL85_RS06385	COG1522	sequence-specific DNA binding
LGL85_RS06390	COG1674	ftsk spoiiie
LGL85_RS06390	COG3107	peptidoglycan biosynthetic process
LGL85_RS06395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL85_RS06400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL85_RS06405	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL85_RS06410	COG2814	Major facilitator Superfamily
LGL85_RS06415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL85_RS06420	COG1882	Formate acetyltransferase
LGL85_RS06425	COG2116	formate transmembrane transporter activity
LGL85_RS06430	COG1944	ATP diphosphatase activity
LGL85_RS06435	COG0252	asparaginase activity
LGL85_RS06445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL85_RS06455	COG0539	negative regulation of cytoplasmic translation
LGL85_RS06465	COG0658	competence protein
LGL85_RS06465	COG2333	competence protein COMEC
LGL85_RS06475	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL85_RS06480	COG5383	Protein conserved in bacteria
LGL85_RS06490	COG1278	Cold shock
LGL85_RS06495	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL85_RS06500	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL85_RS06505	COG3173	Aminoglycoside phosphotransferase
LGL85_RS06510	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL85_RS06515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL85_RS06520	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL85_RS06530	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL85_RS06535	COG2989	Protein conserved in bacteria
LGL85_RS06540	COG3108	Peptidase M15
LGL85_RS06545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL85_RS06550	COG1448	Aminotransferase
LGL85_RS06565	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL85_RS06570	COG0308	aminopeptidase N
LGL85_RS06575	COG0167	dihydroorotate dehydrogenase activity
LGL85_RS06585	COG0633	Ferredoxin
LGL85_RS06585	COG3217	Mosc domain protein beta barrel domain protein
LGL85_RS06590	COG0116	Belongs to the methyltransferase superfamily
LGL85_RS06590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL85_RS06595	COG0488	(ABC) transporter
LGL85_RS06600	COG2995	paraquat-inducible protein a
LGL85_RS06605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL85_RS06605	COG3008	intermembrane lipid transfer
LGL85_RS06610	COG3009	Protein conserved in bacteria
LGL85_RS06615	COG3130	regulation of translation
LGL85_RS06620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL85_RS06625	COG1067	ATP-dependent peptidase activity
LGL85_RS06630	COG3120	sequence-specific DNA binding
LGL85_RS06640	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL85_RS06645	COG3070	regulator of competence-specific genes
LGL85_RS06650	COG1289	transmembrane transporter activity
LGL85_RS06655	COG3304	Inner membrane component domain
LGL85_RS06660	COG0210	DNA helicase
LGL85_RS06665	COG1803	Methylglyoxal synthase
LGL85_RS06675	COG1832	CoA-binding protein
LGL85_RS06680	COG3785	DNA binding
LGL85_RS06685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL85_RS06690	COG1254	Belongs to the acylphosphatase family
LGL85_RS06695	COG2920	part of a sulfur-relay system
LGL85_RS06705	COG0288	reversible hydration of carbon dioxide
LGL85_RS06725	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL85_RS06730	COG2943	transferase activity, transferring hexosyl groups
LGL85_RS06745	COG0675	Transposase, IS605 OrfB family
LGL85_RS06760	COG1560	Kdo2-lipid A biosynthetic process
LGL85_RS06770	COG0628	permease
LGL85_RS06795	COG0418	dihydroorotase activity
LGL85_RS06800	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGL85_RS06810	COG1530	ribonuclease E activity
LGL85_RS06815	COG0564	pseudouridine synthase activity
LGL85_RS06820	COG0424	maF-like protein
LGL85_RS06825	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL85_RS06830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL85_RS06840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL85_RS06845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL85_RS06855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL85_RS06860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL85_RS06865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL85_RS06870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL85_RS06875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL85_RS06880	COG0470	DNA polymerase III
LGL85_RS06885	COG0084	hydrolase, TatD family'
LGL85_RS06890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_RS06890	COG1263	PTS System
LGL85_RS06895	COG0537	adenosine 5'-monophosphoramidase activity
LGL85_RS06900	COG5633	Lipoprotein
LGL85_RS06905	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL85_RS06920	COG3150	esterase
LGL85_RS06925	COG1252	NADH dehydrogenase
LGL85_RS06930	COG3134	Outer membrane lipoprotein
LGL85_RS06935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL85_RS06940	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL85_RS06950	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL85_RS06970	COG2850	peptidyl-arginine hydroxylation
LGL85_RS06975	COG2205	protein histidine kinase activity
LGL85_RS06980	COG0745	RESPONSE REGULATOR receiver
LGL85_RS06990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL85_RS06995	COG2915	High frequency lysogenization protein hflD homolog
LGL85_RS07000	COG0482	sulfurtransferase activity
LGL85_RS07010	COG1187	pseudouridine synthase activity
LGL85_RS07015	COG0538	isocitrate dehydrogenase activity
LGL85_RS07020	COG0582	viral genome integration into host DNA
LGL85_RS07060	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL85_RS07065	COG5532	Uncharacterized conserved protein (DUF2303)
LGL85_RS07115	COG1802	Transcriptional regulator
LGL85_RS07115	COG4626	Terminase
LGL85_RS07120	COG0270	DNA (cytosine-5-)-methyltransferase activity
LGL85_RS07150	COG1403	HNH endonuclease
LGL85_RS07185	COG3179	chitinase
LGL85_RS07195	COG3646	Phage regulatory protein
LGL85_RS07210	COG4626	Terminase
LGL85_RS07210	COG1802	Transcriptional regulator
LGL85_RS07290	COG1674	ftsk spoiiie
LGL85_RS07290	COG1178	ABC-type Fe3 transport system permease component
LGL85_RS07335	COG2771	luxR family
LGL85_RS07340	COG3916	Acyl-homoserine-lactone synthase
LGL85_RS07345	COG2723	6-phospho-beta-galactosidase activity
LGL85_RS07355	COG0339	signal peptide processing
LGL85_RS07360	COG0840	transmembrane signaling receptor activity
LGL85_RS07385	COG0675	Transposase, IS605 OrfB family
LGL85_RS07395	COG4565	transcriptional regulatory protein
LGL85_RS07400	COG3290	protein histidine kinase activity
LGL85_RS07405	COG0471	metal ion transport
LGL85_RS07445	COG4977	sequence-specific DNA binding
LGL85_RS07450	COG1702	phosphate starvation-inducible protein PhoH
LGL85_RS07455	COG0387	Pfam Sodium calcium exchanger
LGL85_RS07460	COG2375	cellular response to nickel ion
LGL85_RS07465	COG3850	Histidine kinase
LGL85_RS07475	COG1294	oxidase, subunit
LGL85_RS07480	COG1271	oxidase subunit
LGL85_RS07485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL85_RS07490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL85_RS07495	COG3138	arginine N-succinyltransferase
LGL85_RS07505	COG3724	N-succinylarginine dihydrolase activity
LGL85_RS07525	COG1228	amidohydrolase
LGL85_RS07535	COG0402	S-adenosylhomocysteine deaminase activity
LGL85_RS07555	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL85_RS07560	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL85_RS07565	COG3383	formate dehydrogenase (NAD+) activity
LGL85_RS07570	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_RS07575	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL85_RS07585	COG3260	NADH ubiquinone oxidoreductase 20
LGL85_RS07590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_RS07595	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL85_RS07595	COG3261	NADH dehydrogenase
LGL85_RS07600	COG0650	Formate hydrogenlyase subunit 4
LGL85_RS07605	COG0651	ATP synthesis coupled electron transport
LGL85_RS07610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_RS07620	COG0375	protein maturation
LGL85_RS07625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL85_RS07630	COG0298	carbon dioxide binding
LGL85_RS07635	COG0409	Hydrogenase expression formation protein
LGL85_RS07640	COG0309	Hydrogenase expression formation protein (HypE)
LGL85_RS07675	COG3708	Transcriptional regulator
LGL85_RS07675	COG2207	Transcriptional regulator
LGL85_RS07680	COG0012	GTP binding
LGL85_RS07690	COG0193	aminoacyl-tRNA hydrolase activity
LGL85_RS07700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL85_RS07710	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL85_RS07715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL85_RS07720	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL85_RS07725	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL85_RS07740	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL85_RS07745	COG0659	secondary active sulfate transmembrane transporter activity
LGL85_RS07750	COG3706	GGDEF domain
LGL85_RS07775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL85_RS07785	COG3381	protein complex oligomerization
LGL85_RS07805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL85_RS07815	COG0673	inositol 2-dehydrogenase activity
LGL85_RS07820	COG0728	peptidoglycan biosynthetic process
LGL85_RS07855	COG3102	Protein conserved in bacteria
LGL85_RS07860	COG3142	Participates in the control of copper homeostasis
LGL85_RS07875	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL85_RS07880	COG1801	Protein of unknown function DUF72
LGL85_RS07890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL85_RS07895	COG0494	nUDIX hydrolase
LGL85_RS07905	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL85_RS07915	COG2255	four-way junction helicase activity
LGL85_RS07920	COG3104	oligopeptide transport
LGL85_RS07925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL85_RS07930	COG1121	(ABC) transporter
LGL85_RS07935	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL85_RS07940	COG0739	heme binding
LGL85_RS07945	COG1560	Kdo2-lipid A biosynthetic process
LGL85_RS07950	COG0469	pyruvate kinase activity
LGL85_RS07955	COG1737	Transcriptional regulator
LGL85_RS07960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL85_RS07965	COG0800	Aldolase
LGL85_RS07975	COG2076	Multidrug Resistance protein
LGL85_RS07980	COG0251	oxidation-reduction process
LGL85_RS07985	COG1199	ATP-dependent helicase activity
LGL85_RS07990	COG1214	PFAM Peptidase M22, glycoprotease
LGL85_RS07995	COG3065	identical protein binding
LGL85_RS08000	COG0318	PFAM AMP-dependent synthetase and ligase
LGL85_RS08005	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL85_RS08010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL85_RS08015	COG2894	cell division
LGL85_RS08020	COG0850	regulation of cytokinetic process
LGL85_RS08025	COG3100	YcgL domain-containing protein
LGL85_RS08030	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL85_RS08035	COG2983	Belongs to the UPF0260 family
LGL85_RS08055	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL85_RS08065	COG2719	SpoVR family
LGL85_RS08070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL85_RS08075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL85_RS08080	COG2814	Major facilitator Superfamily
LGL85_RS08090	COG2199	diguanylate cyclase activity
LGL85_RS08090	COG2200	EAL domain
LGL85_RS08090	COG2202	Pas domain
LGL85_RS08110	COG2718	Belongs to the UPF0229 family
LGL85_RS08115	COG2766	serine protein kinase
LGL85_RS08125	COG3713	MltA-interacting MipA family protein
LGL85_RS08130	COG2194	sulfuric ester hydrolase activity
LGL85_RS08145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL85_RS08150	COG3139	Protein of unknown function (DUF1315)
LGL85_RS08155	COG1335	isochorismatase
LGL85_RS08160	COG0252	asparaginase activity
LGL85_RS08165	COG0616	signal peptide processing
LGL85_RS08170	COG0778	Nitroreductase
LGL85_RS08180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL85_RS08190	COG0494	nUDIX hydrolase
LGL85_RS08195	COG0708	Exodeoxyribonuclease III
LGL85_RS08225	COG0788	formyltetrahydrofolate deformylase activity
LGL85_RS08235	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL85_RS08240	COG0745	RESPONSE REGULATOR receiver
LGL85_RS08260	COG1012	belongs to the aldehyde dehydrogenase family
LGL85_RS08260	COG1454	alcohol dehydrogenase
LGL85_RS08270	COG2095	MarC family integral membrane protein
LGL85_RS08275	COG4166	transmembrane transport
LGL85_RS08290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL85_RS08305	COG3099	Belongs to the UPF0263 family
LGL85_RS08310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL85_RS08330	COG2350	Protein conserved in bacteria
LGL85_RS08345	COG3710	Transcriptional regulator
LGL85_RS08380	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL85_RS08405	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL85_RS08410	COG3047	cAMP biosynthetic process
LGL85_RS08425	COG0133	tryptophan synthase activity
LGL85_RS08430	COG0134	indole-3-glycerol-phosphate synthase activity
LGL85_RS08430	COG0135	phosphoribosylanthranilate isomerase activity
LGL85_RS08440	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL85_RS08450	COG0613	PHP domain protein
LGL85_RS08455	COG0009	L-threonylcarbamoyladenylate synthase
LGL85_RS08470	COG1187	pseudouridine synthase activity
LGL85_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_RS08485	COG0616	signal peptide processing
LGL85_RS08500	COG0583	DNA-binding transcription factor activity
LGL85_RS08515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL85_RS08525	COG0671	phosphoesterase, PA-phosphatase related
LGL85_RS08530	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL85_RS08535	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL85_RS08555	COG0023	Translation Initiation Factor
LGL85_RS08565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL85_RS08570	COG3447	MASE1 domain protein
LGL85_RS08570	COG5001	Diguanylate cyclase
LGL85_RS08570	COG5002	protein histidine kinase activity
LGL85_RS08575	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL85_RS08580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL85_RS08590	COG4659	FMN binding
LGL85_RS08600	COG3708	Transcriptional regulator
LGL85_RS08600	COG2207	Transcriptional regulator
LGL85_RS08615	COG4657	Part of a membrane complex involved in electron transport
LGL85_RS08625	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL85_RS08635	COG0673	inositol 2-dehydrogenase activity
LGL85_RS08640	COG0385	Bile acid
LGL85_RS08645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL85_RS08650	COG5339	Protein conserved in bacteria
LGL85_RS08655	COG1482	cell wall glycoprotein biosynthetic process
LGL85_RS08660	COG0114	fumarate hydratase activity
LGL85_RS08670	COG1940	carbohydrate kinase activity
LGL85_RS08675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL85_RS08695	COG1742	UPF0060 membrane protein
LGL85_RS08700	COG4221	oxidoreductase activity
LGL85_RS08705	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL85_RS08725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL85_RS08765	COG1011	Hydrolase
LGL85_RS08775	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL85_RS08780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL85_RS08785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL85_RS08790	COG0589	response to stress
LGL85_RS08820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL85_RS08825	COG3623	hexulose-6-phosphate isomerase
LGL85_RS08830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL85_RS08835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL85_RS08845	COG0531	amino acid
LGL85_RS08855	COG0745	RESPONSE REGULATOR receiver
LGL85_RS08860	COG2205	protein histidine kinase activity
LGL85_RS08875	COG2207	Transcriptional regulator
LGL85_RS08880	COG1881	PFAM PEBP family protein
LGL85_RS08890	COG3591	Belongs to the peptidase S1B family
LGL85_RS08895	COG1643	Atp-dependent helicase
LGL85_RS08900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL85_RS08905	COG3784	Protein of unknown function (DUF1318)
LGL85_RS08920	COG2911	Protein conserved in bacteria
LGL85_RS08925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL85_RS08930	COG3187	Heat shock protein
LGL85_RS08935	COG3042	response to heat
LGL85_RS08940	COG1285	pathogenesis
LGL85_RS08950	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL85_RS08950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL85_RS08950	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_RS08950	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL85_RS08965	COG4166	transmembrane transport
LGL85_RS08970	COG2866	Carboxypeptidase
LGL85_RS08975	COG4948	Mandelate Racemase Muconate Lactonizing
LGL85_RS08980	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL85_RS08990	COG5642	Protein of unknown function (DUF2384)
LGL85_RS08995	COG5654	RES domain protein
LGL85_RS09000	COG3768	UPF0283 membrane protein
LGL85_RS09005	COG3106	COG3106 Predicted ATPase
LGL85_RS09015	COG1983	PspC domain protein
LGL85_RS09025	COG1842	Phage shock protein A
LGL85_RS09030	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LGL85_RS09045	COG4166	transmembrane transport
LGL85_RS09055	COG4171	peptide transport system, permease
LGL85_RS09060	COG4172	Belongs to the ABC transporter superfamily
LGL85_RS09065	COG4172	Belongs to the ABC transporter superfamily
LGL85_RS09075	COG3104	oligopeptide transport
LGL85_RS09085	COG0484	heat shock protein binding
LGL85_RS09130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL85_RS09135	COG3133	Outer membrane lipoprotein
LGL85_RS09140	COG1846	Transcriptional regulator
LGL85_RS09150	COG4989	oxidoreductase activity
LGL85_RS09155	COG3313	Fe-S protein
LGL85_RS09160	COG2194	sulfuric ester hydrolase activity
LGL85_RS09165	COG1309	transcriptional regulator
LGL85_RS09170	COG1902	pentaerythritol trinitrate reductase activity
LGL85_RS09185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL85_RS09190	COG0791	NLP P60 protein
LGL85_RS09195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL85_RS09205	COG1609	Transcriptional regulator
LGL85_RS09210	COG0583	DNA-binding transcription factor activity
LGL85_RS09215	COG2814	Major facilitator Superfamily
LGL85_RS09220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL85_RS09225	COG0307	riboflavin synthase, alpha
LGL85_RS09260	COG1376	ErfK ybiS ycfS ynhG family protein
LGL85_RS09260	COG1388	LysM domain
LGL85_RS09265	COG2166	iron-sulfur cluster assembly
LGL85_RS09275	COG0719	Fe-S assembly protein
LGL85_RS09280	COG0396	ATPase activity
LGL85_RS09285	COG0719	Fe-S assembly protein
LGL85_RS09290	COG0316	Belongs to the HesB IscA family
LGL85_RS09295	COG2050	protein possibly involved in aromatic compounds catabolism
LGL85_RS09300	COG0277	FAD linked oxidase domain protein
LGL85_RS09300	COG0247	lactate metabolic process
LGL85_RS09305	COG0628	permease
LGL85_RS09315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL85_RS09315	COG0574	Belongs to the PEP-utilizing enzyme family
LGL85_RS09320	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL85_RS09325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL85_RS09335	COG4771	TonB-dependent receptor
LGL85_RS09340	COG3720	iron ion transport
LGL85_RS09345	COG4558	Periplasmic binding protein
LGL85_RS09350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_RS09355	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL85_RS09365	COG0095	Lipoate-protein ligase
LGL85_RS09370	COG0791	NLP P60 protein
LGL85_RS09375	COG2076	Multidrug Resistance protein
LGL85_RS09380	COG2076	Multidrug Resistance protein
LGL85_RS09385	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL85_RS09400	COG0463	Glycosyl transferase, family 2
LGL85_RS09405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL85_RS09415	COG4139	cobalamin transport
LGL85_RS09460	COG2184	nucleotidyltransferase activity
LGL85_RS09475	COG2314	TM2 domain
LGL85_RS09480	COG0776	regulation of translation
LGL85_RS09550	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL85_RS09555	COG1121	(ABC) transporter
LGL85_RS09560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL85_RS09565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL85_RS09570	COG3001	Fructosamine kinase
LGL85_RS09580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL85_RS09585	COG1988	membrane-bound metal-dependent
LGL85_RS09590	COG1823	symporter activity
LGL85_RS09595	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL85_RS09605	COG2814	Major facilitator Superfamily
LGL85_RS09615	COG0501	Belongs to the peptidase M48B family
LGL85_RS09620	COG0793	Belongs to the peptidase S41A family
LGL85_RS09630	COG1956	GAF domain-containing protein
LGL85_RS09635	COG2995	paraquat-inducible protein a
LGL85_RS09640	COG3008	intermembrane lipid transfer
LGL85_RS09645	COG4251	negative regulation of phosphorylation
LGL85_RS09645	COG5001	Diguanylate cyclase
LGL85_RS09645	COG3706	GGDEF domain
LGL85_RS09645	COG2203	Gaf domain
LGL85_RS09725	COG1276	copper resistance
LGL85_RS09730	COG2372	response to copper ion
LGL85_RS09735	COG1528	Iron-storage protein
LGL85_RS09750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL85_RS09755	COG1770	oligopeptidase
LGL85_RS09765	COG3097	Belongs to the UPF0267 family
LGL85_RS09770	COG3141	response to X-ray
LGL85_RS09775	COG0513	Belongs to the DEAD box helicase family
LGL85_RS09795	COG0494	nUDIX hydrolase
LGL85_RS09800	COG1760	l-serine dehydratase
LGL85_RS09805	COG1253	flavin adenine dinucleotide binding
LGL85_RS09810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_RS09810	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_RS09815	COG3715	PTS system
LGL85_RS09820	COG3716	PTS system mannose fructose sorbose family IID component
LGL85_RS09825	COG4811	Protein of unknown function (DUF986)
LGL85_RS09830	COG1971	Probably functions as a manganese efflux pump
LGL85_RS09850	COG1960	acyl-CoA dehydrogenase activity
LGL85_RS09860	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL85_RS09890	COG2226	methyltransferase
LGL85_RS09895	COG0768	penicillin binding
LGL85_RS09900	COG1496	oxidoreductase activity
LGL85_RS09920	COG1113	amino acid transport
LGL85_RS09955	COG2207	Transcriptional regulator
LGL85_RS09975	COG1132	(ABC) transporter
LGL85_RS09985	COG2203	Gaf domain
LGL85_RS09985	COG3706	GGDEF domain
LGL85_RS09985	COG4251	negative regulation of phosphorylation
LGL85_RS09985	COG5001	Diguanylate cyclase
LGL85_RS10005	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL85_RS10025	COG1278	Cold shock
LGL85_RS10030	COG1278	Cold shock
LGL85_RS10035	COG1278	Cold shock
LGL85_RS10050	COG1917	Cupin 2, conserved barrel domain protein
LGL85_RS10050	COG2169	Transcriptional regulator
LGL85_RS10055	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL85_RS10060	COG2723	6-phospho-beta-galactosidase activity
LGL85_RS10065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL85_RS10070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL85_RS10075	COG1187	pseudouridine synthase activity
LGL85_RS10085	COG3122	Protein conserved in bacteria
LGL85_RS10090	COG1757	Na H antiporter
LGL85_RS10105	COG2235	arginine
LGL85_RS10120	COG0076	glutamate decarboxylase activity
LGL85_RS10125	COG0531	amino acid
LGL85_RS10160	COG2153	protein acetylation
LGL85_RS10165	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL85_RS10195	COG0840	transmembrane signaling receptor activity
LGL85_RS10200	COG2801	Transposase and inactivated derivatives
LGL85_RS10220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL85_RS10225	COG0322	excinuclease ABC activity
LGL85_RS10230	COG2197	response regulator
LGL85_RS10255	COG1113	amino acid transport
LGL85_RS10265	COG0531	amino acid
LGL85_RS10270	COG3710	Transcriptional regulator
LGL85_RS10275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL85_RS10280	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL85_RS10280	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL85_RS10280	COG0506	proline dehydrogenase activity
LGL85_RS10285	COG1126	abc transporter atp-binding protein
LGL85_RS10290	COG0765	amino acid transport
LGL85_RS10295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_RS10300	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL85_RS10310	COG1191	sigma factor activity
LGL85_RS10350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL85_RS10355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL85_RS10370	COG1677	Flagellar hook-basal body complex protein FliE
LGL85_RS10380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL85_RS10385	COG1317	bacterial-type flagellum organization
LGL85_RS10390	COG1157	protein secretion by the type III secretion system
LGL85_RS10405	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL85_RS10485	COG1558	bacterial-type flagellum-dependent cell motility
LGL85_RS10490	COG1815	bacterial-type flagellum-dependent cell motility
LGL85_RS10500	COG2747	anti-sigma28 factor FlgM
LGL85_RS10505	COG3418	PFAM FlgN family protein
LGL85_RS10515	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL85_RS10520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL85_RS10530	COG2197	response regulator
LGL85_RS10545	COG3188	usher protein
LGL85_RS10550	COG3121	Chaperone
LGL85_RS10560	COG3539	Fimbrial protein
LGL85_RS10590	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL85_RS10595	COG0745	RESPONSE REGULATOR receiver
LGL85_RS10605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL85_RS10610	COG0840	transmembrane signaling receptor activity
LGL85_RS10615	COG0840	transmembrane signaling receptor activity
LGL85_RS10620	COG0835	chemotaxis
LGL85_RS10625	COG0643	Histidine kinase
LGL85_RS10625	COG2198	Histidine kinase
LGL85_RS10630	COG1360	Flagellar Motor Protein
LGL85_RS10650	COG0589	response to stress
LGL85_RS10655	COG1285	pathogenesis
LGL85_RS10660	COG0840	transmembrane signaling receptor activity
LGL85_RS10680	COG1609	Transcriptional regulator
LGL85_RS10690	COG0604	alcohol dehydrogenase
LGL85_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_RS10690	COG3321	synthase
LGL85_RS10710	COG3423	Transcriptional regulator
LGL85_RS10775	COG4382	Mu-like prophage protein Gp16
LGL85_RS10830	COG4383	Mu-like prophage protein gp29
LGL85_RS10855	COG4397	Mu-like prophage major head subunit gpT
LGL85_RS10880	COG4386	tail sheath protein
LGL85_RS10930	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL85_RS10950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGL85_RS10975	COG0582	viral genome integration into host DNA
LGL85_RS10990	COG3423	Transcriptional regulator
LGL85_RS11025	COG3451	type IV secretory pathway VirB4
LGL85_RS11045	COG3736	Type IV secretory pathway, component VirB8
LGL85_RS11060	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LGL85_RS11075	COG4227	nucleotidyltransferase activity
LGL85_RS11125	COG0471	metal ion transport
LGL85_RS11140	COG3051	citrate lyase alpha subunit
LGL85_RS11145	COG2301	Belongs to the HpcH HpaI aldolase family
LGL85_RS11150	COG3052	prosthetic group binding
LGL85_RS11155	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL85_RS11160	COG3290	protein histidine kinase activity
LGL85_RS11165	COG4565	transcriptional regulatory protein
LGL85_RS11180	COG2271	Major facilitator Superfamily
LGL85_RS11185	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL85_RS11195	COG3842	ATPase activity
LGL85_RS11215	COG1289	transmembrane transporter activity
LGL85_RS11225	COG2925	Exonuclease
LGL85_RS11230	COG0531	amino acid
LGL85_RS11235	COG4771	TonB-dependent receptor
LGL85_RS11245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_RS11255	COG0833	amino acid
LGL85_RS11260	COG0583	DNA-binding transcription factor activity
LGL85_RS11270	COG2855	membrane
LGL85_RS11275	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL85_RS11280	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL85_RS11280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL85_RS11280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL85_RS11285	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL85_RS11300	COG3005	denitrification pathway
LGL85_RS11305	COG0243	molybdopterin cofactor binding
LGL85_RS11320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL85_RS11330	COG0246	Mannitol dehydrogenase
LGL85_RS11340	COG0523	cobalamin synthesis protein
LGL85_RS11345	COG0671	phosphoesterase, PA-phosphatase related
LGL85_RS11350	COG0791	NLP P60 protein
LGL85_RS11355	COG2200	EAL domain
LGL85_RS11360	COG4166	transmembrane transport
LGL85_RS11365	COG4174	ABC transporter (Permease)
LGL85_RS11370	COG4239	(ABC) transporter, permease
LGL85_RS11375	COG4172	Belongs to the ABC transporter superfamily
LGL85_RS11385	COG2814	Major facilitator Superfamily
LGL85_RS11390	COG1187	pseudouridine synthase activity
LGL85_RS11395	COG1061	Type III restriction enzyme res subunit
LGL85_RS11410	COG3082	Protein of unknown function (DUF1414)
LGL85_RS11415	COG3083	sulfuric ester hydrolase activity
LGL85_RS11440	COG3778	Protein conserved in bacteria
LGL85_RS11445	COG3299	homolog of phage Mu protein gp47
LGL85_RS11490	COG4386	tail sheath protein
LGL85_RS11540	COG1802	Transcriptional regulator
LGL85_RS11540	COG4626	Terminase
LGL85_RS11590	COG1403	HNH endonuclease
LGL85_RS11615	COG4626	Terminase
LGL85_RS11615	COG1802	Transcriptional regulator
LGL85_RS11665	COG5532	Uncharacterized conserved protein (DUF2303)
LGL85_RS11670	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL85_RS11720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL85_RS11725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL85_RS11745	COG2223	nitrite transmembrane transporter activity
LGL85_RS11750	COG2198	Histidine kinase
LGL85_RS11750	COG0642	Histidine kinase
LGL85_RS11760	COG2205	protein histidine kinase activity
LGL85_RS11760	COG0784	Response regulator, receiver
LGL85_RS11770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL85_RS11775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL85_RS11785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL85_RS11795	COG4574	serine-type endopeptidase inhibitor activity
LGL85_RS11805	COG2246	polysaccharide biosynthetic process
LGL85_RS11820	COG0814	amino acid
LGL85_RS11845	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL85_RS11850	COG0596	Alpha beta hydrolase
LGL85_RS11855	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL85_RS11860	COG1169	isochorismate synthase
LGL85_RS11865	COG4575	ribosome binding
LGL85_RS11880	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_RS11885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL85_RS11895	COG0839	Belongs to the complex I subunit 6 family
LGL85_RS11900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_RS11905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL85_RS11910	COG1034	ATP synthesis coupled electron transport
LGL85_RS11930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_RS11935	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_RS11940	COG0583	DNA-binding transcription factor activity
LGL85_RS11945	COG0436	Aminotransferase
LGL85_RS11950	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL85_RS11955	COG0490	domain, Protein
LGL85_RS11955	COG0471	metal ion transport
LGL85_RS11965	COG3013	Belongs to the UPF0304 family
LGL85_RS11970	COG3092	negative regulation of chromosome organization
LGL85_RS11980	COG0280	phosphate acetyltransferase
LGL85_RS11980	COG0857	belongs to the CobB CobQ family
LGL85_RS11985	COG1609	Transcriptional regulator
LGL85_RS12000	COG3037	sugar-specific permease SgaT UlaA
LGL85_RS12005	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL85_RS12010	COG0622	Phosphoesterase
LGL85_RS12025	COG0625	glutathione transferase activity
LGL85_RS12030	COG1090	epimerase
LGL85_RS12040	COG4160	amino acid transport
LGL85_RS12045	COG4215	(ABC) transporter
LGL85_RS12060	COG0163	prenyltransferase activity
LGL85_RS12065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL85_RS12070	COG1286	toxin biosynthetic process
LGL85_RS12075	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL85_RS12080	COG0285	dihydrofolate synthase activity
LGL85_RS12090	COG0586	Pfam SNARE associated Golgi protein
LGL85_RS12100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL85_RS12125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL85_RS12130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL85_RS12160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL85_RS12175	COG3101	peptidyl-lysine hydroxylation
LGL85_RS12180	COG0730	response to heat
LGL85_RS12185	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL85_RS12195	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL85_RS12200	COG2840	Smr protein MutS2
LGL85_RS12205	COG2062	phosphohistidine phosphatase, SixA
LGL85_RS12210	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL85_RS12210	COG1024	Enoyl-CoA hydratase
LGL85_RS12215	COG0183	Belongs to the thiolase family
LGL85_RS12220	COG3691	Protein conserved in bacteria
LGL85_RS12235	COG4235	cytochrome complex assembly
LGL85_RS12235	COG3088	subunit of a heme lyase
LGL85_RS12240	COG4235	cytochrome complex assembly
LGL85_RS12240	COG3088	subunit of a heme lyase
LGL85_RS12245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL85_RS12250	COG1138	Cytochrome C-type biogenesis protein
LGL85_RS12255	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL85_RS12260	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL85_RS12265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL85_RS12270	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL85_RS12285	COG0582	viral genome integration into host DNA
LGL85_RS12295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LGL85_RS12350	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL85_RS12355	COG2951	lytic endotransglycosylase activity
LGL85_RS12360	COG1598	PFAM Uncharacterised protein family UPF0150
LGL85_RS12370	COG3038	cytochrome b561
LGL85_RS12375	COG0436	Aminotransferase
LGL85_RS12385	COG3275	phosphorelay sensor kinase activity
LGL85_RS12390	COG3279	Response regulator of the LytR AlgR family
LGL85_RS12395	COG2223	nitrite transmembrane transporter activity
LGL85_RS12400	COG0837	glucose binding
LGL85_RS12420	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL85_RS12425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL85_RS12495	COG3530	Putative quorum-sensing-regulated virulence factor
LGL85_RS12500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL85_RS12510	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL85_RS12520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_RS12535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL85_RS12545	COG4208	sulfate ABC transporter
LGL85_RS12550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL85_RS12555	COG4150	thiosulfate binding
LGL85_RS12565	COG1737	Transcriptional regulator
LGL85_RS12570	COG2731	YhcH YjgK YiaL family protein
LGL85_RS12585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL85_RS12590	COG2837	iron assimilation
LGL85_RS12600	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL85_RS12660	COG1671	Belongs to the UPF0178 family
LGL85_RS12665	COG0281	malic enzyme
LGL85_RS12665	COG0280	phosphate acetyltransferase
LGL85_RS12670	COG0494	nUDIX hydrolase
LGL85_RS12675	COG3005	denitrification pathway
LGL85_RS12680	COG3043	anaerobic respiration
LGL85_RS12685	COG0243	molybdopterin cofactor binding
LGL85_RS12690	COG3062	negative regulation of establishment of protein localization
LGL85_RS12695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_RS12695	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_RS12700	COG2197	response regulator
LGL85_RS12710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL85_RS12720	COG1605	Chorismate mutase
LGL85_RS12725	COG1393	Belongs to the ArsC family
LGL85_RS12730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL85_RS12735	COG1876	peptidase activity
LGL85_RS12745	COG0400	carboxylic ester hydrolase activity
LGL85_RS12765	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL85_RS12770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL85_RS12775	COG2716	regulation of RNA biosynthetic process
LGL85_RS12780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL85_RS12785	COG0628	permease
LGL85_RS12790	COG4783	chaperone-mediated protein folding
LGL85_RS12795	COG1393	Belongs to the ArsC family
LGL85_RS12800	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL85_RS12805	COG2233	PERMEase
LGL85_RS12810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL85_RS12815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL85_RS12820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL85_RS12825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL85_RS12835	COG0581	inorganic phosphate transmembrane transporter activity
LGL85_RS12840	COG0573	inorganic phosphate transmembrane transporter activity
LGL85_RS12845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL85_RS12860	COG2239	Acts as a magnesium transporter
LGL85_RS12865	COG0443	Heat shock 70 kDa protein
LGL85_RS12875	COG3121	Chaperone
LGL85_RS12895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_RS12905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL85_RS12910	COG0477	Major facilitator Superfamily
LGL85_RS12915	COG2205	protein histidine kinase activity
LGL85_RS12920	COG0745	RESPONSE REGULATOR receiver
LGL85_RS12925	COG3422	double-strand break repair
LGL85_RS12930	COG0826	peptidase U32
LGL85_RS12935	COG1597	lipid kinase activity
LGL85_RS12950	COG0351	phosphomethylpyrimidine kinase
LGL85_RS12965	COG0519	Catalyzes the synthesis of GMP from XMP
LGL85_RS12965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL85_RS12970	COG0517	IMP dehydrogenase activity
LGL85_RS12970	COG0516	GMP reductase activity
LGL85_RS12975	COG1570	exodeoxyribonuclease VII activity
LGL85_RS12980	COG1645	bacterial-type flagellum-dependent swarming motility
LGL85_RS12990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL85_RS12995	COG2976	Protein conserved in bacteria
LGL85_RS13000	COG0124	histidyl-tRNA synthetase
LGL85_RS13020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL85_RS13035	COG4953	penicillin-binding protein 1C
LGL85_RS13040	COG2373	Large extracellular alpha-helical protein
LGL85_RS13055	COG2975	iron-sulfur cluster assembly
LGL85_RS13060	COG0633	Ferredoxin
LGL85_RS13065	COG0443	Heat shock 70 kDa protein
LGL85_RS13080	COG0822	iron-sulfur transferase activity
LGL85_RS13090	COG1959	2 iron, 2 sulfur cluster binding
LGL85_RS13095	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL85_RS13105	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL85_RS13110	COG3683	transport system, periplasmic component
LGL85_RS13115	COG3711	transcriptional antiterminator
LGL85_RS13120	COG2814	Major facilitator Superfamily
LGL85_RS13130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL85_RS13130	COG1017	nitric oxide dioxygenase activity
LGL85_RS13135	COG2188	Transcriptional regulator
LGL85_RS13145	COG3457	Alanine racemase
LGL85_RS13150	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL85_RS13165	COG0347	Belongs to the P(II) protein family
LGL85_RS13170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL85_RS13170	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL85_RS13175	COG2204	response regulator
LGL85_RS13180	COG3170	Tfp pilus assembly protein FimV
LGL85_RS13185	COG2205	protein histidine kinase activity
LGL85_RS13200	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL85_RS13210	COG0560	Phosphoserine phosphatase
LGL85_RS13215	COG1263	PTS System
LGL85_RS13215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_RS13225	COG1737	Transcriptional regulator
LGL85_RS13230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_RS13240	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL85_RS13250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL85_RS13265	COG0481	GTPase activity
LGL85_RS13270	COG3086	response to oxidative stress
LGL85_RS13280	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL85_RS13290	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL85_RS13300	COG0513	Belongs to the DEAD box helicase family
LGL85_RS13315	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL85_RS13325	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL85_RS13330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL85_RS13335	COG0497	DNA recombination
LGL85_RS13340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL85_RS13350	COG2867	negative regulation of translational initiation
LGL85_RS13355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL85_RS13365	COG0582	viral genome integration into host DNA
LGL85_RS13400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL85_RS13495	COG3121	Chaperone
LGL85_RS13500	COG3188	usher protein
LGL85_RS13525	COG0583	DNA-binding transcription factor activity
LGL85_RS13600	COG1069	ribulokinase activity
LGL85_RS13610	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL85_RS13615	COG1129	ABC transporter
LGL85_RS13635	COG1620	l-lactate permease
LGL85_RS13640	COG1304	FMN binding
LGL85_RS13645	COG0579	oxidoreductase
LGL85_RS13650	COG1278	Cold shock
LGL85_RS13680	COG1780	Probably involved in ribonucleotide reductase function
LGL85_RS13685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL85_RS13695	COG4175	Glycine betaine
LGL85_RS13700	COG4176	ABC-type proline glycine betaine transport system permease component
LGL85_RS13705	COG2113	Glycine betaine
LGL85_RS13715	COG2814	Major facilitator Superfamily
LGL85_RS13720	COG1846	Transcriptional regulator
LGL85_RS13730	COG1566	PFAM secretion protein HlyD family protein
LGL85_RS13735	COG2814	Major facilitator Superfamily
LGL85_RS13740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL85_RS13745	COG3118	belongs to the thioredoxin family
LGL85_RS13750	COG3148	PFAM DTW domain containing protein
LGL85_RS13755	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL85_RS13755	COG1042	CoA-binding domain protein
LGL85_RS13755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL85_RS13760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL85_RS13765	COG5544	Lipoprotein
LGL85_RS13790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL85_RS13800	COG2011	ABC-type metal ion transport system permease component
LGL85_RS13805	COG1464	Belongs to the NlpA lipoprotein family
LGL85_RS13815	COG1720	tRNA m6t6A37 methyltransferase activity
LGL85_RS13820	COG0442	prolyl-tRNA aminoacylation
LGL85_RS13825	COG3015	lipoprotein NlpE involved in copper resistance
LGL85_RS13835	COG4681	YaeQ
LGL85_RS13845	COG4568	rho-dependent transcription termination
LGL85_RS13860	COG0346	lactoylglutathione lyase activity
LGL85_RS13875	COG0825	malonyl-CoA metabolic process
LGL85_RS13880	COG0587	DNA-directed DNA polymerase activity
LGL85_RS13885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL85_RS13905	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL85_RS13910	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL85_RS13920	COG0750	zinc metalloprotease
LGL85_RS13925	COG0575	Belongs to the CDS family
LGL85_RS13945	COG0528	UMP kinase activity
LGL85_RS13950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL85_RS13965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL85_RS13970	COG2171	N-acyltransferase activity
LGL85_RS13985	COG0564	pseudouridine synthase activity
LGL85_RS13990	COG3098	single-species biofilm formation
LGL85_RS14005	COG1611	Belongs to the LOG family
LGL85_RS14015	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL85_RS14020	COG2363	Small membrane protein
LGL85_RS14025	COG0583	DNA-binding transcription factor activity
LGL85_RS14035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL85_RS14040	COG2166	iron-sulfur cluster assembly
LGL85_RS14045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL85_RS14050	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL85_RS14070	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL85_RS14075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL85_RS14075	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL85_RS14080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL85_RS14085	COG1074	ATP-dependent DNA helicase activity
LGL85_RS14090	COG1025	Belongs to the peptidase M16 family
LGL85_RS14095	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL85_RS14100	COG4967	type IV pilus modification protein PilV
LGL85_RS14125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL85_RS14130	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL85_RS14140	COG3066	DNA modification
LGL85_RS14145	COG0861	Integral membrane protein TerC family
LGL85_RS14150	COG0667	Aldo Keto reductase
LGL85_RS14155	COG0477	Major facilitator Superfamily
LGL85_RS14160	COG0318	PFAM AMP-dependent synthetase and ligase
LGL85_RS14160	COG0204	Acyl-transferase
LGL85_RS14165	COG1609	Transcriptional regulator
LGL85_RS14175	COG0583	DNA-binding transcription factor activity
LGL85_RS14180	COG0583	DNA-binding transcription factor activity
LGL85_RS14230	COG4795	General secretion pathway protein
LGL85_RS14245	COG2165	general secretion pathway protein
LGL85_RS14260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL85_RS14290	COG1127	ABC transporter
LGL85_RS14295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL85_RS14305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL85_RS14315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL85_RS14320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL85_RS14325	COG4974	Belongs to the 'phage' integrase family
LGL85_RS14330	COG0716	FMN binding
LGL85_RS14340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL85_RS14350	COG1272	protein, Hemolysin III
LGL85_RS14370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL85_RS14375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL85_RS14380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL85_RS14385	COG0006	proline dipeptidase activity
LGL85_RS14395	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL85_RS14405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL85_RS14410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL85_RS14415	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL85_RS14430	COG1279	arginine transmembrane transporter activity
LGL85_RS14440	COG0191	fructose-bisphosphate aldolase activity
LGL85_RS14445	COG0126	phosphoglycerate kinase activity
LGL85_RS14450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL85_RS14455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL85_RS14465	COG1166	arginine decarboxylase activity
LGL85_RS14470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL85_RS14485	COG0640	Transcriptional regulator
LGL85_RS14490	COG3091	SprT-like family
LGL85_RS14495	COG2356	endonuclease I
LGL85_RS14500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL85_RS14505	COG0189	ligase activity
LGL85_RS14510	COG1678	Uncharacterized ACR, COG1678
LGL85_RS14515	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL85_RS14520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL85_RS14530	COG2805	Type II/IV secretion system protein
LGL85_RS14535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL85_RS14540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL85_RS14545	COG0762	integral membrane protein
LGL85_RS14550	COG1872	DUF167
LGL85_RS14555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL85_RS14560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL85_RS14575	COG3171	Protein conserved in bacteria
LGL85_RS14585	COG1194	a g-specific adenine glycosylase
LGL85_RS14590	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL85_RS14595	COG0741	lytic transglycosylase activity
LGL85_RS14630	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL85_RS14635	COG1882	Formate acetyltransferase
LGL85_RS14640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL85_RS14645	COG0814	amino acid
LGL85_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_RS14665	COG1535	isochorismatase
LGL85_RS14665	COG3433	isochorismatase activity
LGL85_RS14670	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL85_RS14675	COG1169	isochorismate synthase
LGL85_RS14680	COG4592	Periplasmic binding protein
LGL85_RS14690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_RS14695	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_RS14700	COG1120	ATPase activity
LGL85_RS14710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL85_RS14715	COG3251	PFAM MbtH domain protein
LGL85_RS14725	COG4774	siderophore transport
LGL85_RS14730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL85_RS14755	COG4964	Belongs to the GSP D family
LGL85_RS14810	COG0848	biopolymer transport protein
LGL85_RS14815	COG0811	peptide transport
LGL85_RS14820	COG0626	cystathionine gamma-synthase activity
LGL85_RS14825	COG0586	Pfam SNARE associated Golgi protein
LGL85_RS14830	COG2207	Transcriptional regulator
LGL85_RS14835	COG1979	alcohol dehydrogenase
LGL85_RS14840	COG0656	L-ascorbic acid biosynthetic process
LGL85_RS14850	COG2132	Multicopper oxidase
LGL85_RS14865	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL85_RS14870	COG0583	DNA-binding transcription factor activity
LGL85_RS14875	COG0187	DNA topoisomerase II activity
LGL85_RS14880	COG3150	esterase
LGL85_RS14885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL85_RS14890	COG3151	Protein conserved in bacteria
LGL85_RS14895	COG0494	nUDIX hydrolase
LGL85_RS14900	COG1538	Outer membrane efflux protein
LGL85_RS14905	COG5463	Belongs to the UPF0441 family
LGL85_RS14910	COG0754	glutathionylspermidine amidase activity
LGL85_RS14915	COG3384	dioxygenase
LGL85_RS14920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL85_RS14935	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL85_RS14935	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL85_RS14945	COG3025	triphosphatase activity
LGL85_RS14950	COG4991	sh3 domain protein
LGL85_RS14955	COG0617	tRNA 3'-terminal CCA addition
LGL85_RS14960	COG1968	undecaprenyl-diphosphatase activity
LGL85_RS14965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL85_RS14970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL85_RS14975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL85_RS14980	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL85_RS14985	COG0358	DNA primase activity
LGL85_RS15015	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_RS15045	COG0463	Glycosyl transferase, family 2
LGL85_RS15085	COG3210	domain, Protein
LGL85_RS15095	COG2831	hemolysin activation secretion protein
LGL85_RS15100	COG1902	pentaerythritol trinitrate reductase activity
LGL85_RS15100	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL85_RS15115	COG1451	nucleotide metabolic process
LGL85_RS15120	COG0673	inositol 2-dehydrogenase activity
LGL85_RS15125	COG0861	Integral membrane protein TerC family
LGL85_RS15130	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL85_RS15140	COG2721	sulfolactate sulfo-lyase activity
LGL85_RS15155	COG2271	Major facilitator Superfamily
LGL85_RS15170	COG0586	Pfam SNARE associated Golgi protein
LGL85_RS15185	COG4575	ribosome binding
LGL85_RS15190	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL85_RS15200	COG2259	Doxx family
LGL85_RS15205	COG0583	DNA-binding transcription factor activity
LGL85_RS15210	COG1741	Belongs to the pirin family
LGL85_RS15225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL85_RS15240	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL85_RS15245	COG2823	Periplasmic or secreted lipoprotein
LGL85_RS15250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL85_RS15255	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL85_RS15260	COG2198	Histidine kinase
LGL85_RS15260	COG0784	Response regulator, receiver
LGL85_RS15260	COG5002	protein histidine kinase activity
LGL85_RS15265	COG1242	4 iron, 4 sulfur cluster binding
LGL85_RS15270	COG0067	glutamate synthase
LGL85_RS15270	COG0070	glutamate synthase
LGL85_RS15270	COG0069	glutamate synthase activity
LGL85_RS15275	COG0493	'glutamate synthase
LGL85_RS15285	COG2969	positive regulation of protein catabolic process
LGL85_RS15290	COG0625	glutathione transferase activity
LGL85_RS15295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL85_RS15300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL85_RS15305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL85_RS15310	COG3105	Protein conserved in bacteria
LGL85_RS15315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL85_RS15325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL85_RS15330	COG5007	Belongs to the BolA IbaG family
LGL85_RS15335	COG3113	response to antibiotic
LGL85_RS15340	COG2854	intermembrane phospholipid transfer
LGL85_RS15345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL85_RS15350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL85_RS15355	COG1127	ABC transporter
LGL85_RS15360	COG0530	calcium, potassium:sodium antiporter activity
LGL85_RS15365	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL85_RS15365	COG0517	IMP dehydrogenase activity
LGL85_RS15370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL85_RS15375	COG3117	lipopolysaccharide transmembrane transporter activity
LGL85_RS15380	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL85_RS15385	COG1137	ATPase activity
LGL85_RS15390	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL85_RS15410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_RS15415	COG0540	Belongs to the ATCase OTCase family
LGL85_RS15420	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL85_RS15430	COG0366	Alpha amylase catalytic
LGL85_RS15435	COG1263	PTS System
LGL85_RS15435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_RS15445	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL85_RS15455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL85_RS15460	COG3783	Cytochrome b(562)
LGL85_RS15465	COG0312	modulator of DNA gyrase
LGL85_RS15470	COG3028	Belongs to the UPF0307 family
LGL85_RS15475	COG2732	(Barnase) inhibitor
LGL85_RS15480	COG4290	ribonuclease
LGL85_RS15490	COG1289	transmembrane transporter activity
LGL85_RS15495	COG1566	PFAM secretion protein HlyD family protein
LGL85_RS15505	COG0583	DNA-binding transcription factor activity
LGL85_RS15510	COG0312	modulator of DNA gyrase
LGL85_RS15515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL85_RS15520	COG3164	Protein of unknown function
LGL85_RS15530	COG0424	maF-like protein
LGL85_RS15535	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL85_RS15540	COG1792	Involved in formation and maintenance of cell shape
LGL85_RS15545	COG1077	Cell shape determining protein MreB Mrl
LGL85_RS15550	COG2200	EAL domain
LGL85_RS15550	COG2199	diguanylate cyclase activity
LGL85_RS15555	COG0604	alcohol dehydrogenase
LGL85_RS15560	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL85_RS15565	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL85_RS15575	COG0511	ligase activity, forming carbon-carbon bonds
LGL85_RS15580	COG0439	Biotin carboxylase
LGL85_RS15585	COG3924	membrane
LGL85_RS15590	COG4145	pantothenate transmembrane transporter activity
LGL85_RS15595	COG2264	protein methyltransferase activity
LGL85_RS15600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL85_RS15605	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL85_RS15615	COG1560	Kdo2-lipid A biosynthetic process
LGL85_RS15625	COG1346	cytolysis
LGL85_RS15630	COG1380	Effector of murein hydrolase LrgA
LGL85_RS15635	COG0583	DNA-binding transcription factor activity
LGL85_RS15640	COG0025	NhaP-type Na H and K H
LGL85_RS15645	COG2252	PERMEase
LGL85_RS15660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL85_RS15665	COG2315	Protein conserved in bacteria
LGL85_RS15670	COG1448	Aminotransferase
LGL85_RS15695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL85_RS15700	COG0735	belongs to the Fur family
LGL85_RS15705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL85_RS15710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL85_RS15715	COG2937	Belongs to the GPAT DAPAT family
LGL85_RS15735	COG4580	involved in the transport of maltose and maltodextrins
LGL85_RS15750	COG2182	Extracellular solute-binding protein
LGL85_RS15755	COG1175	transmembrane transport
LGL85_RS15760	COG3833	ABC-type maltose transport systems, permease component
LGL85_RS15765	COG3223	Belongs to the PsiE family
LGL85_RS15775	COG0527	aspartate kinase activity
LGL85_RS15790	COG3328	transposase activity
LGL85_RS15820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGL85_RS15900	COG0583	DNA-binding transcription factor activity
LGL85_RS15935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL85_RS15975	COG0138	bifunctional purine biosynthesis protein purh
LGL85_RS15980	COG0151	Belongs to the GarS family
LGL85_RS16000	COG1515	deoxyribonuclease V activity
LGL85_RS16005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL85_RS16010	COG2816	NAD+ diphosphatase activity
LGL85_RS16015	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL85_RS16030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL85_RS16035	COG2104	thiamine diphosphate biosynthetic process
LGL85_RS16040	COG2022	thiamine diphosphate biosynthetic process
LGL85_RS16050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL85_RS16055	COG0085	RNA polymerase activity
LGL85_RS16060	COG0222	ribosome binding
LGL85_RS16065	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL85_RS16075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL85_RS16080	COG0250	Participates in transcription elongation, termination and antitermination
LGL85_RS16125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL85_RS16150	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL85_RS16155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL85_RS16160	COG1739	Uncharacterized protein family UPF0029
LGL85_RS16170	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL85_RS16170	COG1024	Enoyl-CoA hydratase
LGL85_RS16180	COG0543	2 iron, 2 sulfur cluster binding
LGL85_RS16195	COG0250	Participates in transcription elongation, termination and antitermination
LGL85_RS16210	COG0805	protein transport
LGL85_RS16215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL85_RS16220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL85_RS16225	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL85_RS16230	COG3165	ubiquinone biosynthetic process from chorismate
LGL85_RS16235	COG2226	methyltransferase
LGL85_RS16240	COG1322	Protein conserved in bacteria
LGL85_RS16245	COG0586	Pfam SNARE associated Golgi protein
LGL85_RS16250	COG1966	Carbon starvation protein
LGL85_RS16265	COG0412	Dienelactone hydrolase
LGL85_RS16270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL85_RS16275	COG0583	DNA-binding transcription factor activity
LGL85_RS16280	COG0697	spore germination
LGL85_RS16290	COG0584	glycerophosphoryl diester phosphodiesterase
LGL85_RS16300	COG0395	ABC-type sugar transport system, permease component
LGL85_RS16305	COG1175	transmembrane transport
LGL85_RS16310	COG1653	transport
LGL85_RS16345	COG0410	ABC transporter
LGL85_RS16355	COG4177	L-phenylalanine transmembrane transporter activity
LGL85_RS16375	COG1929	Belongs to the glycerate kinase type-1 family
LGL85_RS16380	COG2610	gluconate transmembrane transporter activity
LGL85_RS16385	COG3835	regulator
LGL85_RS16395	COG2177	Part of the ABC transporter FtsEX involved in
LGL85_RS16400	COG2884	Cell division ATP-binding protein ftsE
LGL85_RS16405	COG0552	protein localization to endoplasmic reticulum
LGL85_RS16405	COG0552	protein localization to endoplasmic reticulum
LGL85_RS16410	COG0742	ribosomal rna small subunit methyltransferase
LGL85_RS16415	COG3776	membrane
LGL85_RS16430	COG3714	YhhN family
LGL85_RS16445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL85_RS16455	COG0247	lactate metabolic process
LGL85_RS16465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL85_RS16475	COG2271	Major facilitator Superfamily
LGL85_RS16480	COG0584	glycerophosphoryl diester phosphodiesterase
LGL85_RS16485	COG0561	phosphatase activity
LGL85_RS16490	COG2267	carboxylic ester hydrolase activity
LGL85_RS16495	COG1280	lysine exporter protein (LysE YggA)
LGL85_RS16500	COG0514	ATP-dependent DNA helicase (RecQ)
LGL85_RS16505	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL85_RS16510	COG2050	protein possibly involved in aromatic compounds catabolism
LGL85_RS16530	COG5564	TIM-barrel signal transduction protein
LGL85_RS16535	COG5441	Belongs to the UPF0261 family
LGL85_RS16545	COG0210	DNA helicase
LGL85_RS16550	COG1011	Hydrolase
LGL85_RS16555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL85_RS16560	COG3159	Protein conserved in bacteria
LGL85_RS16565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL85_RS16570	COG5567	small periplasmic lipoprotein
LGL85_RS16580	COG3072	Adenylate cyclase
LGL85_RS16585	COG0181	hydroxymethylbilane synthase activity
LGL85_RS16590	COG1587	Uroporphyrinogen-III synthase
LGL85_RS16595	COG2959	enzyme of heme biosynthesis
LGL85_RS16600	COG3071	HemY protein
LGL85_RS16650	COG2244	polysaccharide biosynthetic process
LGL85_RS16655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL85_RS16660	COG0456	acetyltransferase
LGL85_RS16665	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL85_RS16670	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL85_RS16675	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL85_RS16680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL85_RS16685	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL85_RS16690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL85_RS16695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL85_RS16700	COG3118	belongs to the thioredoxin family
LGL85_RS16710	COG0248	Ppx GppA phosphatase
LGL85_RS16720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL85_RS16735	COG3397	chitin binding
LGL85_RS16745	COG0129	dihydroxy-acid dehydratase activity
LGL85_RS16755	COG3978	acetolactate synthase activity
LGL85_RS16775	COG3085	chromosome segregation
LGL85_RS16780	COG0583	DNA-binding transcription factor activity
LGL85_RS16855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL85_RS16865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL85_RS16865	COG0678	peroxiredoxin activity
LGL85_RS16870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL85_RS16905	COG1629	transport
LGL85_RS16910	COG0165	Argininosuccinate lyase
LGL85_RS16915	COG0137	argininosuccinate synthase activity
LGL85_RS16920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL85_RS16965	COG0460	homoserine dehydrogenase
LGL85_RS16965	COG0527	aspartate kinase activity
LGL85_RS16970	COG0626	cystathionine gamma-synthase activity
LGL85_RS16975	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL85_RS16985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL85_RS16990	COG1609	Transcriptional regulator
LGL85_RS16995	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL85_RS17000	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL85_RS17005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL85_RS17010	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL85_RS17015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL85_RS17020	COG3074	FtsZ-dependent cytokinesis
LGL85_RS17025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL85_RS17030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL85_RS17035	COG1494	fructose-1,6-bisphosphatase
LGL85_RS17040	COG2814	Major facilitator Superfamily
LGL85_RS17050	COG3152	Membrane
LGL85_RS17065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL85_RS17075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL85_RS17080	COG3678	ATP-independent chaperone mediated protein folding
LGL85_RS17085	COG0745	RESPONSE REGULATOR receiver
LGL85_RS17090	COG2205	protein histidine kinase activity
LGL85_RS17095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL85_RS17100	COG1045	serine acetyltransferase
LGL85_RS17105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL85_RS17110	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL85_RS17115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL85_RS17120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL85_RS17125	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL85_RS17130	COG4942	peptidase
LGL85_RS17135	COG2861	carbohydrate metabolic process
LGL85_RS17150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL85_RS17155	COG0859	PFAM glycosyl transferase family 9
LGL85_RS17160	COG0859	PFAM glycosyl transferase family 9
LGL85_RS17165	COG1519	Transferase
LGL85_RS17185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL85_RS17190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL85_RS17195	COG2003	Belongs to the UPF0758 family
LGL85_RS17200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL85_RS17205	COG0756	dUTP diphosphatase activity
LGL85_RS17210	COG1309	transcriptional regulator
LGL85_RS17215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL85_RS17220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL85_RS17225	COG1561	YicC-like family, N-terminal region
LGL85_RS17240	COG5001	Diguanylate cyclase
LGL85_RS17245	COG1024	Enoyl-CoA hydratase
LGL85_RS17250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL85_RS17265	COG2860	membrane
LGL85_RS17270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL85_RS17280	COG1758	RNA polymerase activity
LGL85_RS17285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL85_RS17290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL85_RS17295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL85_RS17300	COG0786	glutamate:sodium symporter activity
LGL85_RS17305	COG2233	PERMEase
LGL85_RS17310	COG2982	Protein involved in outer membrane biogenesis
LGL85_RS17315	COG0456	acetyltransferase
LGL85_RS17330	COG1011	Hydrolase
LGL85_RS17345	COG3852	Histidine kinase
LGL85_RS17355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL85_RS17365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL85_RS17370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL85_RS17370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL85_RS17375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL85_RS17380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL85_RS17385	COG3084	Protein conserved in bacteria
LGL85_RS17395	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL85_RS17420	COG2186	Transcriptional regulator
LGL85_RS17425	COG1609	Transcriptional regulator
LGL85_RS17430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL85_RS17440	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL85_RS17445	COG1129	ABC transporter
LGL85_RS17450	COG1869	D-ribose catabolic process
LGL85_RS17455	COG3158	transport of potassium into the cell
LGL85_RS17460	COG0714	Associated with various cellular activities
LGL85_RS17465	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL85_RS17475	COG2502	aspartate--ammonia ligase
LGL85_RS17480	COG1522	sequence-specific DNA binding
LGL85_RS17485	COG0716	FMN binding
LGL85_RS17490	COG0445	tRNA wobble uridine modification
LGL85_RS17495	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL85_RS17500	COG3312	ion transport
LGL85_RS17505	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL85_RS17515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL85_RS17525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL85_RS17530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL85_RS17540	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL85_RS17555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL85_RS17560	COG0573	inorganic phosphate transmembrane transporter activity
LGL85_RS17565	COG0581	inorganic phosphate transmembrane transporter activity
LGL85_RS17575	COG0704	Plays a role in the regulation of phosphate uptake
LGL85_RS17580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_RS17585	COG0765	amino acid transport
LGL85_RS17590	COG0765	amino acid transport
LGL85_RS17595	COG2252	PERMEase
LGL85_RS17600	COG0840	transmembrane signaling receptor activity
LGL85_RS17610	COG3121	Chaperone
LGL85_RS17625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL85_RS17630	COG0706	membrane insertase activity
LGL85_RS17640	COG0594	ribonuclease P activity
LGL85_RS17645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGL85_RS17945	COG3093	addiction module antidote protein HigA
LGL85_RS17950	COG3549	Plasmid maintenance system killer
LGL85_RS17965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL85_RS17990	COG1122	ATPase activity
LGL85_RS18015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGL85_RS18025	COG0431	NADPH-dependent FMN reductase
LGL85_RS18030	COG0640	Transcriptional regulator