locus-tag	class	description
UGYR_RS00010	COG0308	aminopeptidase N
UGYR_RS00015	COG0167	dihydroorotate dehydrogenase activity
UGYR_RS00025	COG0633	Ferredoxin
UGYR_RS00025	COG3217	Mosc domain protein beta barrel domain protein
UGYR_RS00030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
UGYR_RS00030	COG0116	Belongs to the methyltransferase superfamily
UGYR_RS00035	COG0488	(ABC) transporter
UGYR_RS00040	COG2995	paraquat-inducible protein a
UGYR_RS00045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
UGYR_RS00045	COG3008	intermembrane lipid transfer
UGYR_RS00050	COG3009	Protein conserved in bacteria
UGYR_RS00055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UGYR_RS00060	COG1067	ATP-dependent peptidase activity
UGYR_RS00065	COG3120	sequence-specific DNA binding
UGYR_RS00075	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
UGYR_RS00080	COG3070	regulator of competence-specific genes
UGYR_RS00085	COG1289	transmembrane transporter activity
UGYR_RS00090	COG3304	Inner membrane component domain
UGYR_RS00095	COG0210	DNA helicase
UGYR_RS00100	COG1803	Methylglyoxal synthase
UGYR_RS00110	COG1832	CoA-binding protein
UGYR_RS00115	COG3785	DNA binding
UGYR_RS00120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
UGYR_RS00125	COG1254	Belongs to the acylphosphatase family
UGYR_RS00130	COG2920	part of a sulfur-relay system
UGYR_RS00140	COG0288	reversible hydration of carbon dioxide
UGYR_RS00160	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
UGYR_RS00165	COG2943	transferase activity, transferring hexosyl groups
UGYR_RS00185	COG1560	Kdo2-lipid A biosynthetic process
UGYR_RS00195	COG0628	permease
UGYR_RS00220	COG0418	dihydroorotase activity
UGYR_RS00225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
UGYR_RS00235	COG1530	ribonuclease E activity
UGYR_RS00240	COG0564	pseudouridine synthase activity
UGYR_RS00245	COG0424	maF-like protein
UGYR_RS00250	COG1399	metal-binding, possibly nucleic acid-binding protein
UGYR_RS00255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
UGYR_RS00265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
UGYR_RS00270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
UGYR_RS00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UGYR_RS00285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UGYR_RS00290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UGYR_RS00295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
UGYR_RS00300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
UGYR_RS00305	COG0470	DNA polymerase III
UGYR_RS00310	COG0084	hydrolase, TatD family'
UGYR_RS00315	COG1263	PTS System
UGYR_RS00315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
UGYR_RS00325	COG5633	Lipoprotein
UGYR_RS00330	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
UGYR_RS00345	COG3150	esterase
UGYR_RS00350	COG1252	NADH dehydrogenase
UGYR_RS00355	COG3134	Outer membrane lipoprotein
UGYR_RS00360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
UGYR_RS00365	COG4591	ABC-type transport system involved in lipoprotein release permease component
UGYR_RS00375	COG4591	ABC-type transport system involved in lipoprotein release permease component
UGYR_RS00395	COG2850	peptidyl-arginine hydroxylation
UGYR_RS00400	COG2205	protein histidine kinase activity
UGYR_RS00405	COG0745	RESPONSE REGULATOR receiver
UGYR_RS00415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
UGYR_RS00420	COG2915	High frequency lysogenization protein hflD homolog
UGYR_RS00425	COG0482	sulfurtransferase activity
UGYR_RS00435	COG1187	pseudouridine synthase activity
UGYR_RS00440	COG0538	isocitrate dehydrogenase activity
UGYR_RS00445	COG2771	luxR family
UGYR_RS00450	COG3916	Acyl-homoserine-lactone synthase
UGYR_RS00455	COG2723	6-phospho-beta-galactosidase activity
UGYR_RS00460	COG0339	signal peptide processing
UGYR_RS00465	COG0840	transmembrane signaling receptor activity
UGYR_RS00470	COG3493	citrate carrier protein
UGYR_RS00475	COG4565	transcriptional regulatory protein
UGYR_RS00480	COG3290	protein histidine kinase activity
UGYR_RS00485	COG0471	metal ion transport
UGYR_RS00525	COG4977	sequence-specific DNA binding
UGYR_RS00530	COG1702	phosphate starvation-inducible protein PhoH
UGYR_RS00535	COG0387	Pfam Sodium calcium exchanger
UGYR_RS00540	COG2375	cellular response to nickel ion
UGYR_RS00545	COG3850	Histidine kinase
UGYR_RS00550	COG1294	oxidase, subunit
UGYR_RS00555	COG1271	oxidase subunit
UGYR_RS00560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UGYR_RS00565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
UGYR_RS00570	COG3138	arginine N-succinyltransferase
UGYR_RS00580	COG3724	N-succinylarginine dihydrolase activity
UGYR_RS00600	COG1228	amidohydrolase
UGYR_RS00610	COG0402	S-adenosylhomocysteine deaminase activity
UGYR_RS00630	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
UGYR_RS00635	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
UGYR_RS00640	COG3383	formate dehydrogenase (NAD+) activity
UGYR_RS00645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_RS00650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
UGYR_RS00660	COG3260	NADH ubiquinone oxidoreductase 20
UGYR_RS00665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_RS00670	COG3261	NADH dehydrogenase
UGYR_RS00670	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
UGYR_RS00675	COG0650	Formate hydrogenlyase subunit 4
UGYR_RS00680	COG0651	ATP synthesis coupled electron transport
UGYR_RS00685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_RS00695	COG0375	protein maturation
UGYR_RS00700	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
UGYR_RS00705	COG0298	carbon dioxide binding
UGYR_RS00710	COG0409	Hydrogenase expression formation protein
UGYR_RS00715	COG0309	Hydrogenase expression formation protein (HypE)
UGYR_RS00755	COG3708	Transcriptional regulator
UGYR_RS00755	COG2207	Transcriptional regulator
UGYR_RS00760	COG0012	GTP binding
UGYR_RS00770	COG0193	aminoacyl-tRNA hydrolase activity
UGYR_RS00780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
UGYR_RS00790	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
UGYR_RS00795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
UGYR_RS00800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
UGYR_RS00805	COG2890	protein-(glutamine-N5) methyltransferase activity
UGYR_RS00820	COG2877	3-deoxy-8-phosphooctulonate synthase activity
UGYR_RS00825	COG0659	secondary active sulfate transmembrane transporter activity
UGYR_RS00840	COG3706	GGDEF domain
UGYR_RS00865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UGYR_RS00875	COG3381	protein complex oligomerization
UGYR_RS00895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UGYR_RS00905	COG0673	inositol 2-dehydrogenase activity
UGYR_RS00910	COG0728	peptidoglycan biosynthetic process
UGYR_RS00935	COG3102	Protein conserved in bacteria
UGYR_RS00940	COG3142	Participates in the control of copper homeostasis
UGYR_RS00955	COG3788	relative of glutathione S-transferase, MAPEG superfamily
UGYR_RS00960	COG1801	Protein of unknown function DUF72
UGYR_RS00970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
UGYR_RS00975	COG0494	nUDIX hydrolase
UGYR_RS00985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
UGYR_RS00995	COG2255	four-way junction helicase activity
UGYR_RS01000	COG3104	oligopeptide transport
UGYR_RS01005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UGYR_RS01010	COG1121	(ABC) transporter
UGYR_RS01015	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
UGYR_RS01020	COG0739	heme binding
UGYR_RS01025	COG1560	Kdo2-lipid A biosynthetic process
UGYR_RS01030	COG0469	pyruvate kinase activity
UGYR_RS01035	COG1737	Transcriptional regulator
UGYR_RS01040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
UGYR_RS01045	COG0800	Aldolase
UGYR_RS01055	COG2076	Multidrug Resistance protein
UGYR_RS01060	COG0251	oxidation-reduction process
UGYR_RS01065	COG1199	ATP-dependent helicase activity
UGYR_RS01070	COG1214	PFAM Peptidase M22, glycoprotease
UGYR_RS01075	COG3065	identical protein binding
UGYR_RS01080	COG0318	PFAM AMP-dependent synthetase and ligase
UGYR_RS01085	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
UGYR_RS01090	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
UGYR_RS01095	COG2894	cell division
UGYR_RS01100	COG0850	regulation of cytokinetic process
UGYR_RS01105	COG3100	YcgL domain-containing protein
UGYR_RS01110	COG0179	Fumarylacetoacetate (FAA) hydrolase
UGYR_RS01115	COG2983	Belongs to the UPF0260 family
UGYR_RS01130	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
UGYR_RS01140	COG2719	SpoVR family
UGYR_RS01145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UGYR_RS01150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
UGYR_RS01165	COG2200	EAL domain
UGYR_RS01165	COG2202	Pas domain
UGYR_RS01165	COG2199	diguanylate cyclase activity
UGYR_RS01185	COG2718	Belongs to the UPF0229 family
UGYR_RS01190	COG2766	serine protein kinase
UGYR_RS01195	COG3713	MltA-interacting MipA family protein
UGYR_RS01200	COG2194	sulfuric ester hydrolase activity
UGYR_RS01215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UGYR_RS01220	COG3139	Protein of unknown function (DUF1315)
UGYR_RS01225	COG1335	isochorismatase
UGYR_RS01230	COG0252	asparaginase activity
UGYR_RS01235	COG0616	signal peptide processing
UGYR_RS01240	COG0778	Nitroreductase
UGYR_RS01250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UGYR_RS01260	COG0494	nUDIX hydrolase
UGYR_RS01265	COG0708	Exodeoxyribonuclease III
UGYR_RS01295	COG0788	formyltetrahydrofolate deformylase activity
UGYR_RS01305	COG1752	Esterase of the alpha-beta hydrolase superfamily
UGYR_RS01310	COG0745	RESPONSE REGULATOR receiver
UGYR_RS01330	COG1012	belongs to the aldehyde dehydrogenase family
UGYR_RS01330	COG1454	alcohol dehydrogenase
UGYR_RS01335	COG2095	MarC family integral membrane protein
UGYR_RS01345	COG4166	transmembrane transport
UGYR_RS01360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UGYR_RS01375	COG3099	Belongs to the UPF0263 family
UGYR_RS01380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UGYR_RS01400	COG2350	Protein conserved in bacteria
UGYR_RS01450	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
UGYR_RS01475	COG0727	PFAM Uncharacterised protein family (UPF0153)
UGYR_RS01480	COG3047	cAMP biosynthetic process
UGYR_RS01495	COG0133	tryptophan synthase activity
UGYR_RS01500	COG0134	indole-3-glycerol-phosphate synthase activity
UGYR_RS01500	COG0135	phosphoribosylanthranilate isomerase activity
UGYR_RS01510	COG0512	Glutamine amidotransferase of anthranilate synthase
UGYR_RS01520	COG0613	PHP domain protein
UGYR_RS01525	COG0009	L-threonylcarbamoyladenylate synthase
UGYR_RS01530	COG1187	pseudouridine synthase activity
UGYR_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_RS01545	COG0616	signal peptide processing
UGYR_RS01560	COG0583	DNA-binding transcription factor activity
UGYR_RS01575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
UGYR_RS01585	COG0671	phosphoesterase, PA-phosphatase related
UGYR_RS01590	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
UGYR_RS01595	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
UGYR_RS01615	COG0023	Translation Initiation Factor
UGYR_RS01625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
UGYR_RS01630	COG5001	Diguanylate cyclase
UGYR_RS01630	COG5002	protein histidine kinase activity
UGYR_RS01630	COG3447	MASE1 domain protein
UGYR_RS01635	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
UGYR_RS01640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
UGYR_RS01650	COG4659	FMN binding
UGYR_RS01660	COG2207	Transcriptional regulator
UGYR_RS01660	COG3708	Transcriptional regulator
UGYR_RS01675	COG4657	Part of a membrane complex involved in electron transport
UGYR_RS01685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
UGYR_RS01695	COG0673	inositol 2-dehydrogenase activity
UGYR_RS01700	COG0385	Bile acid
UGYR_RS01705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
UGYR_RS01710	COG5339	Protein conserved in bacteria
UGYR_RS01715	COG1482	cell wall glycoprotein biosynthetic process
UGYR_RS01720	COG0114	fumarate hydratase activity
UGYR_RS01730	COG1940	carbohydrate kinase activity
UGYR_RS01735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UGYR_RS01755	COG1742	UPF0060 membrane protein
UGYR_RS01760	COG4221	oxidoreductase activity
UGYR_RS01765	COG3023	N-Acetylmuramoyl-L-alanine amidase
UGYR_RS01785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
UGYR_RS01825	COG1011	Hydrolase
UGYR_RS01835	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
UGYR_RS01840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
UGYR_RS01845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UGYR_RS01850	COG0589	response to stress
UGYR_RS01880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
UGYR_RS01885	COG3623	hexulose-6-phosphate isomerase
UGYR_RS01890	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
UGYR_RS01895	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
UGYR_RS01905	COG0531	amino acid
UGYR_RS01915	COG0745	RESPONSE REGULATOR receiver
UGYR_RS01920	COG2205	protein histidine kinase activity
UGYR_RS01935	COG2207	Transcriptional regulator
UGYR_RS01940	COG1881	PFAM PEBP family protein
UGYR_RS01950	COG3591	Belongs to the peptidase S1B family
UGYR_RS01955	COG1643	Atp-dependent helicase
UGYR_RS01965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
UGYR_RS01970	COG3784	Protein of unknown function (DUF1318)
UGYR_RS01985	COG2911	Protein conserved in bacteria
UGYR_RS01990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UGYR_RS01995	COG3187	Heat shock protein
UGYR_RS02000	COG3042	response to heat
UGYR_RS02005	COG1285	pathogenesis
UGYR_RS02015	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
UGYR_RS02015	COG1013	pyruvate-flavodoxin oxidoreductase activity
UGYR_RS02015	COG0674	pyruvate-flavodoxin oxidoreductase activity
UGYR_RS02015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_RS02030	COG4166	transmembrane transport
UGYR_RS02035	COG2866	Carboxypeptidase
UGYR_RS02040	COG4948	Mandelate Racemase Muconate Lactonizing
UGYR_RS02045	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
UGYR_RS02055	COG5642	Protein of unknown function (DUF2384)
UGYR_RS02065	COG3768	UPF0283 membrane protein
UGYR_RS02070	COG3106	COG3106 Predicted ATPase
UGYR_RS02080	COG1983	PspC domain protein
UGYR_RS02090	COG1842	Phage shock protein A
UGYR_RS02095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
UGYR_RS02115	COG4166	transmembrane transport
UGYR_RS02125	COG4171	peptide transport system, permease
UGYR_RS02130	COG4172	Belongs to the ABC transporter superfamily
UGYR_RS02135	COG4172	Belongs to the ABC transporter superfamily
UGYR_RS02145	COG3104	oligopeptide transport
UGYR_RS02155	COG0484	heat shock protein binding
UGYR_RS02200	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
UGYR_RS02205	COG3133	Outer membrane lipoprotein
UGYR_RS02210	COG1846	Transcriptional regulator
UGYR_RS02215	COG4989	oxidoreductase activity
UGYR_RS02220	COG3313	Fe-S protein
UGYR_RS02225	COG2194	sulfuric ester hydrolase activity
UGYR_RS02230	COG1309	transcriptional regulator
UGYR_RS02235	COG1902	pentaerythritol trinitrate reductase activity
UGYR_RS02250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
UGYR_RS02255	COG0791	NLP P60 protein
UGYR_RS02260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UGYR_RS02265	COG1609	Transcriptional regulator
UGYR_RS02270	COG0583	DNA-binding transcription factor activity
UGYR_RS02275	COG2814	Major facilitator Superfamily
UGYR_RS02280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UGYR_RS02285	COG0307	riboflavin synthase, alpha
UGYR_RS02325	COG1388	LysM domain
UGYR_RS02325	COG1376	ErfK ybiS ycfS ynhG family protein
UGYR_RS02330	COG2166	iron-sulfur cluster assembly
UGYR_RS02340	COG0719	Fe-S assembly protein
UGYR_RS02345	COG0396	ATPase activity
UGYR_RS02350	COG0719	Fe-S assembly protein
UGYR_RS02355	COG0316	Belongs to the HesB IscA family
UGYR_RS02360	COG2050	protein possibly involved in aromatic compounds catabolism
UGYR_RS02365	COG0277	FAD linked oxidase domain protein
UGYR_RS02365	COG0247	lactate metabolic process
UGYR_RS02370	COG0628	permease
UGYR_RS02375	COG0574	Belongs to the PEP-utilizing enzyme family
UGYR_RS02375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UGYR_RS02380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
UGYR_RS02385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UGYR_RS02390	COG4771	TonB-dependent receptor
UGYR_RS02395	COG3720	iron ion transport
UGYR_RS02400	COG4558	Periplasmic binding protein
UGYR_RS02405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_RS02410	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
UGYR_RS02420	COG0095	Lipoate-protein ligase
UGYR_RS02425	COG0791	NLP P60 protein
UGYR_RS02430	COG2076	Multidrug Resistance protein
UGYR_RS02435	COG2076	Multidrug Resistance protein
UGYR_RS02440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
UGYR_RS02455	COG0463	Glycosyl transferase, family 2
UGYR_RS02460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UGYR_RS02465	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
UGYR_RS02470	COG4139	cobalamin transport
UGYR_RS02480	COG4974	Belongs to the 'phage' integrase family
UGYR_RS02515	COG2314	TM2 domain
UGYR_RS02520	COG0776	regulation of translation
UGYR_RS02595	COG0803	Belongs to the bacterial solute-binding protein 9 family
UGYR_RS02600	COG1121	(ABC) transporter
UGYR_RS02605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UGYR_RS02610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UGYR_RS02615	COG3001	Fructosamine kinase
UGYR_RS02625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UGYR_RS02630	COG1988	membrane-bound metal-dependent
UGYR_RS02635	COG1823	symporter activity
UGYR_RS02640	COG3023	N-Acetylmuramoyl-L-alanine amidase
UGYR_RS02650	COG2814	Major facilitator Superfamily
UGYR_RS02655	COG0501	Belongs to the peptidase M48B family
UGYR_RS02660	COG0793	Belongs to the peptidase S41A family
UGYR_RS02670	COG1956	GAF domain-containing protein
UGYR_RS02675	COG2995	paraquat-inducible protein a
UGYR_RS02680	COG3008	intermembrane lipid transfer
UGYR_RS02685	COG3706	GGDEF domain
UGYR_RS02685	COG5001	Diguanylate cyclase
UGYR_RS02685	COG4251	negative regulation of phosphorylation
UGYR_RS02685	COG2203	Gaf domain
UGYR_RS02800	COG4695	Portal protein
UGYR_RS02895	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
UGYR_RS02940	COG4974	Belongs to the 'phage' integrase family
UGYR_RS02950	COG1276	copper resistance
UGYR_RS02955	COG2372	response to copper ion
UGYR_RS02960	COG1528	Iron-storage protein
UGYR_RS02975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
UGYR_RS02980	COG1770	oligopeptidase
UGYR_RS02990	COG3097	Belongs to the UPF0267 family
UGYR_RS02995	COG3141	response to X-ray
UGYR_RS03000	COG0513	Belongs to the DEAD box helicase family
UGYR_RS03020	COG0494	nUDIX hydrolase
UGYR_RS03025	COG1760	l-serine dehydratase
UGYR_RS03030	COG1253	flavin adenine dinucleotide binding
UGYR_RS03035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_RS03035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_RS03040	COG3715	PTS system
UGYR_RS03045	COG3716	PTS system mannose fructose sorbose family IID component
UGYR_RS03050	COG4811	Protein of unknown function (DUF986)
UGYR_RS03055	COG1971	Probably functions as a manganese efflux pump
UGYR_RS03075	COG1960	acyl-CoA dehydrogenase activity
UGYR_RS03085	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
UGYR_RS03115	COG2226	methyltransferase
UGYR_RS03120	COG0768	penicillin binding
UGYR_RS03125	COG1496	oxidoreductase activity
UGYR_RS03140	COG1113	amino acid transport
UGYR_RS03180	COG2207	Transcriptional regulator
UGYR_RS03195	COG1132	(ABC) transporter
UGYR_RS03205	COG5001	Diguanylate cyclase
UGYR_RS03205	COG3706	GGDEF domain
UGYR_RS03205	COG2203	Gaf domain
UGYR_RS03205	COG4251	negative regulation of phosphorylation
UGYR_RS03225	COG1181	Belongs to the D-alanine--D-alanine ligase family
UGYR_RS03245	COG1278	Cold shock
UGYR_RS03250	COG1278	Cold shock
UGYR_RS03265	COG1917	Cupin 2, conserved barrel domain protein
UGYR_RS03265	COG2169	Transcriptional regulator
UGYR_RS03270	COG1447	Phosphotransferase system cellobiose-specific component IIA
UGYR_RS03275	COG2723	6-phospho-beta-galactosidase activity
UGYR_RS03280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
UGYR_RS03285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
UGYR_RS03295	COG1187	pseudouridine synthase activity
UGYR_RS03305	COG3122	Protein conserved in bacteria
UGYR_RS03310	COG1757	Na H antiporter
UGYR_RS03325	COG2235	arginine
UGYR_RS03340	COG0076	glutamate decarboxylase activity
UGYR_RS03345	COG0531	amino acid
UGYR_RS03380	COG2153	protein acetylation
UGYR_RS03390	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
UGYR_RS03425	COG0840	transmembrane signaling receptor activity
UGYR_RS03450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UGYR_RS03455	COG0322	excinuclease ABC activity
UGYR_RS03460	COG2197	response regulator
UGYR_RS03480	COG1113	amino acid transport
UGYR_RS03490	COG0531	amino acid
UGYR_RS03495	COG3710	Transcriptional regulator
UGYR_RS03500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UGYR_RS03505	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
UGYR_RS03505	COG0506	proline dehydrogenase activity
UGYR_RS03505	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
UGYR_RS03510	COG1126	abc transporter atp-binding protein
UGYR_RS03515	COG0765	amino acid transport
UGYR_RS03520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_RS03525	COG2515	1-aminocyclopropane-1-carboxylate deaminase
UGYR_RS03535	COG1191	sigma factor activity
UGYR_RS03575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
UGYR_RS03580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UGYR_RS03595	COG1677	Flagellar hook-basal body complex protein FliE
UGYR_RS03605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UGYR_RS03615	COG1157	protein secretion by the type III secretion system
UGYR_RS03630	COG1580	Controls the rotational direction of flagella during chemotaxis
UGYR_RS03700	COG1749	Flagellar hook protein flgE
UGYR_RS03710	COG1558	bacterial-type flagellum-dependent cell motility
UGYR_RS03715	COG1815	bacterial-type flagellum-dependent cell motility
UGYR_RS03725	COG2747	anti-sigma28 factor FlgM
UGYR_RS03730	COG3418	PFAM FlgN family protein
UGYR_RS03745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UGYR_RS03750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UGYR_RS03755	COG1404	Belongs to the peptidase S8 family
UGYR_RS03755	COG4935	Belongs to the peptidase S8 family
UGYR_RS03760	COG2197	response regulator
UGYR_RS03780	COG3188	usher protein
UGYR_RS03785	COG3121	Chaperone
UGYR_RS03795	COG3539	Fimbrial protein
UGYR_RS03825	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
UGYR_RS03830	COG0745	RESPONSE REGULATOR receiver
UGYR_RS03840	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
UGYR_RS03845	COG0840	transmembrane signaling receptor activity
UGYR_RS03850	COG0840	transmembrane signaling receptor activity
UGYR_RS03855	COG0835	chemotaxis
UGYR_RS03860	COG2198	Histidine kinase
UGYR_RS03860	COG0643	Histidine kinase
UGYR_RS03865	COG1360	Flagellar Motor Protein
UGYR_RS03890	COG0589	response to stress
UGYR_RS03895	COG1285	pathogenesis
UGYR_RS03900	COG0840	transmembrane signaling receptor activity
UGYR_RS03920	COG1609	Transcriptional regulator
UGYR_RS03930	COG3321	synthase
UGYR_RS03930	COG0604	alcohol dehydrogenase
UGYR_RS03930	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_RS03975	COG0471	metal ion transport
UGYR_RS03990	COG3051	citrate lyase alpha subunit
UGYR_RS03995	COG2301	Belongs to the HpcH HpaI aldolase family
UGYR_RS04000	COG3052	prosthetic group binding
UGYR_RS04005	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
UGYR_RS04010	COG3290	protein histidine kinase activity
UGYR_RS04015	COG4565	transcriptional regulatory protein
UGYR_RS04030	COG2271	Major facilitator Superfamily
UGYR_RS04035	COG1840	ABC-type Fe3 transport system, periplasmic component
UGYR_RS04045	COG3842	ATPase activity
UGYR_RS04065	COG1289	transmembrane transporter activity
UGYR_RS04075	COG2925	Exonuclease
UGYR_RS04080	COG0531	amino acid
UGYR_RS04085	COG4771	TonB-dependent receptor
UGYR_RS04095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_RS04105	COG0833	amino acid
UGYR_RS04110	COG0583	DNA-binding transcription factor activity
UGYR_RS04125	COG2855	membrane
UGYR_RS04130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
UGYR_RS04135	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
UGYR_RS04135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
UGYR_RS04135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
UGYR_RS04140	COG1105	Belongs to the carbohydrate kinase PfkB family
UGYR_RS04155	COG3005	denitrification pathway
UGYR_RS04160	COG0243	molybdopterin cofactor binding
UGYR_RS04175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
UGYR_RS04185	COG0246	Mannitol dehydrogenase
UGYR_RS04195	COG0523	cobalamin synthesis protein
UGYR_RS04200	COG0671	phosphoesterase, PA-phosphatase related
UGYR_RS04205	COG0791	NLP P60 protein
UGYR_RS04210	COG2200	EAL domain
UGYR_RS04215	COG4166	transmembrane transport
UGYR_RS04220	COG4174	ABC transporter (Permease)
UGYR_RS04225	COG4239	(ABC) transporter, permease
UGYR_RS04230	COG4172	Belongs to the ABC transporter superfamily
UGYR_RS04240	COG2814	Major facilitator Superfamily
UGYR_RS04245	COG1187	pseudouridine synthase activity
UGYR_RS04265	COG3082	Protein of unknown function (DUF1414)
UGYR_RS04275	COG3083	sulfuric ester hydrolase activity
UGYR_RS04280	COG3083	sulfuric ester hydrolase activity
UGYR_RS04295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
UGYR_RS04315	COG3778	Protein conserved in bacteria
UGYR_RS04320	COG3299	homolog of phage Mu protein gp47
UGYR_RS04365	COG4386	tail sheath protein
UGYR_RS04405	COG0740	serine-type endopeptidase activity
UGYR_RS04415	COG1802	Transcriptional regulator
UGYR_RS04415	COG4626	Terminase
UGYR_RS04430	COG3646	Phage regulatory protein
UGYR_RS04465	COG1403	HNH endonuclease
UGYR_RS04490	COG0270	DNA (cytosine-5-)-methyltransferase activity
UGYR_RS04495	COG1802	Transcriptional regulator
UGYR_RS04495	COG4626	Terminase
UGYR_RS04545	COG5532	Uncharacterized conserved protein (DUF2303)
UGYR_RS04550	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
UGYR_RS04585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
UGYR_RS04590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UGYR_RS04610	COG2223	nitrite transmembrane transporter activity
UGYR_RS04615	COG2198	Histidine kinase
UGYR_RS04615	COG0642	Histidine kinase
UGYR_RS04625	COG0784	Response regulator, receiver
UGYR_RS04625	COG2205	protein histidine kinase activity
UGYR_RS04635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UGYR_RS04640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UGYR_RS04650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UGYR_RS04660	COG4574	serine-type endopeptidase inhibitor activity
UGYR_RS04670	COG2246	polysaccharide biosynthetic process
UGYR_RS04685	COG0814	amino acid
UGYR_RS04710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
UGYR_RS04715	COG0596	Alpha beta hydrolase
UGYR_RS04720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
UGYR_RS04725	COG1169	isochorismate synthase
UGYR_RS04730	COG4575	ribosome binding
UGYR_RS04745	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_RS04750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
UGYR_RS04760	COG0839	Belongs to the complex I subunit 6 family
UGYR_RS04765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_RS04770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
UGYR_RS04775	COG1034	ATP synthesis coupled electron transport
UGYR_RS04795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_RS04800	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_RS04805	COG0583	DNA-binding transcription factor activity
UGYR_RS04815	COG0436	Aminotransferase
UGYR_RS04820	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
UGYR_RS04825	COG0490	domain, Protein
UGYR_RS04825	COG0471	metal ion transport
UGYR_RS04835	COG3013	Belongs to the UPF0304 family
UGYR_RS04840	COG3092	negative regulation of chromosome organization
UGYR_RS04850	COG0280	phosphate acetyltransferase
UGYR_RS04850	COG0857	belongs to the CobB CobQ family
UGYR_RS04855	COG1609	Transcriptional regulator
UGYR_RS04870	COG3037	sugar-specific permease SgaT UlaA
UGYR_RS04875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
UGYR_RS04880	COG0622	Phosphoesterase
UGYR_RS04890	COG0625	glutathione transferase activity
UGYR_RS04895	COG1090	epimerase
UGYR_RS04905	COG4160	amino acid transport
UGYR_RS04910	COG4215	(ABC) transporter
UGYR_RS04920	COG0163	prenyltransferase activity
UGYR_RS04925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
UGYR_RS04930	COG1286	toxin biosynthetic process
UGYR_RS04935	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
UGYR_RS04940	COG0285	dihydrofolate synthase activity
UGYR_RS04950	COG0586	Pfam SNARE associated Golgi protein
UGYR_RS04960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UGYR_RS04985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UGYR_RS04990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UGYR_RS05030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UGYR_RS05045	COG3101	peptidyl-lysine hydroxylation
UGYR_RS05050	COG0730	response to heat
UGYR_RS05055	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
UGYR_RS05065	COG2890	protein-(glutamine-N5) methyltransferase activity
UGYR_RS05070	COG2840	Smr protein MutS2
UGYR_RS05075	COG2062	phosphohistidine phosphatase, SixA
UGYR_RS05080	COG1024	Enoyl-CoA hydratase
UGYR_RS05080	COG1250	3-hydroxyacyl-CoA dehydrogenase
UGYR_RS05085	COG0183	Belongs to the thiolase family
UGYR_RS05090	COG3691	Protein conserved in bacteria
UGYR_RS05105	COG3088	subunit of a heme lyase
UGYR_RS05105	COG4235	cytochrome complex assembly
UGYR_RS05110	COG4235	cytochrome complex assembly
UGYR_RS05110	COG3088	subunit of a heme lyase
UGYR_RS05115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UGYR_RS05120	COG1138	Cytochrome C-type biogenesis protein
UGYR_RS05125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
UGYR_RS05130	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UGYR_RS05135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UGYR_RS05140	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UGYR_RS05160	COG2824	Alkylphosphonate utilization operon protein PhnA
UGYR_RS05165	COG2951	lytic endotransglycosylase activity
UGYR_RS05170	COG1598	PFAM Uncharacterised protein family UPF0150
UGYR_RS05175	COG3038	cytochrome b561
UGYR_RS05180	COG0436	Aminotransferase
UGYR_RS05190	COG3275	phosphorelay sensor kinase activity
UGYR_RS05195	COG3279	Response regulator of the LytR AlgR family
UGYR_RS05200	COG2223	nitrite transmembrane transporter activity
UGYR_RS05205	COG0837	glucose binding
UGYR_RS05225	COG1914	H( )-stimulated, divalent metal cation uptake system
UGYR_RS05230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
UGYR_RS05295	COG3530	Putative quorum-sensing-regulated virulence factor
UGYR_RS05300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UGYR_RS05310	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
UGYR_RS05320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_RS05335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UGYR_RS05345	COG4208	sulfate ABC transporter
UGYR_RS05350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
UGYR_RS05365	COG1737	Transcriptional regulator
UGYR_RS05370	COG2731	YhcH YjgK YiaL family protein
UGYR_RS05385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UGYR_RS05390	COG2837	iron assimilation
UGYR_RS05400	COG3111	PFAM Bacterial OB fold (BOF) protein
UGYR_RS05415	COG1671	Belongs to the UPF0178 family
UGYR_RS05420	COG0280	phosphate acetyltransferase
UGYR_RS05420	COG0281	malic enzyme
UGYR_RS05425	COG0494	nUDIX hydrolase
UGYR_RS05430	COG3005	denitrification pathway
UGYR_RS05435	COG3043	anaerobic respiration
UGYR_RS05440	COG0243	molybdopterin cofactor binding
UGYR_RS05445	COG3062	negative regulation of establishment of protein localization
UGYR_RS05450	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_RS05450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_RS05460	COG2197	response regulator
UGYR_RS05470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UGYR_RS05480	COG1605	Chorismate mutase
UGYR_RS05485	COG1393	Belongs to the ArsC family
UGYR_RS05490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UGYR_RS05495	COG1876	peptidase activity
UGYR_RS05505	COG0400	carboxylic ester hydrolase activity
UGYR_RS05525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
UGYR_RS05530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UGYR_RS05535	COG2716	regulation of RNA biosynthetic process
UGYR_RS05540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UGYR_RS05545	COG0628	permease
UGYR_RS05550	COG4783	chaperone-mediated protein folding
UGYR_RS05555	COG1393	Belongs to the ArsC family
UGYR_RS05560	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UGYR_RS05565	COG2233	PERMEase
UGYR_RS05570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
UGYR_RS05575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
UGYR_RS05580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
UGYR_RS05585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UGYR_RS05595	COG0581	inorganic phosphate transmembrane transporter activity
UGYR_RS05600	COG0573	inorganic phosphate transmembrane transporter activity
UGYR_RS05610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
UGYR_RS05625	COG2239	Acts as a magnesium transporter
UGYR_RS05630	COG0443	Heat shock 70 kDa protein
UGYR_RS05640	COG3121	Chaperone
UGYR_RS05660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_RS05670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UGYR_RS05675	COG0477	Major facilitator Superfamily
UGYR_RS05680	COG2205	protein histidine kinase activity
UGYR_RS05685	COG0745	RESPONSE REGULATOR receiver
UGYR_RS05690	COG3422	double-strand break repair
UGYR_RS05695	COG0826	peptidase U32
UGYR_RS05700	COG1597	lipid kinase activity
UGYR_RS05715	COG0351	phosphomethylpyrimidine kinase
UGYR_RS05800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UGYR_RS05800	COG0519	Catalyzes the synthesis of GMP from XMP
UGYR_RS05805	COG0517	IMP dehydrogenase activity
UGYR_RS05805	COG0516	GMP reductase activity
UGYR_RS05810	COG1570	exodeoxyribonuclease VII activity
UGYR_RS05820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UGYR_RS05825	COG2976	Protein conserved in bacteria
UGYR_RS05830	COG0124	histidyl-tRNA synthetase
UGYR_RS05865	COG4953	penicillin-binding protein 1C
UGYR_RS05870	COG2373	Large extracellular alpha-helical protein
UGYR_RS05885	COG2975	iron-sulfur cluster assembly
UGYR_RS05890	COG0633	Ferredoxin
UGYR_RS05895	COG0443	Heat shock 70 kDa protein
UGYR_RS05910	COG0822	iron-sulfur transferase activity
UGYR_RS05920	COG1959	2 iron, 2 sulfur cluster binding
UGYR_RS05925	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
UGYR_RS05935	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
UGYR_RS05940	COG3683	transport system, periplasmic component
UGYR_RS05945	COG3711	transcriptional antiterminator
UGYR_RS05950	COG2814	Major facilitator Superfamily
UGYR_RS05960	COG1017	nitric oxide dioxygenase activity
UGYR_RS05960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UGYR_RS05965	COG2188	Transcriptional regulator
UGYR_RS05975	COG3457	Alanine racemase
UGYR_RS05980	COG1735	metal-dependent hydrolase with the TIM-barrel fold
UGYR_RS05995	COG0347	Belongs to the P(II) protein family
UGYR_RS06000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UGYR_RS06000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
UGYR_RS06005	COG2204	response regulator
UGYR_RS06010	COG3170	Tfp pilus assembly protein FimV
UGYR_RS06015	COG2205	protein histidine kinase activity
UGYR_RS06035	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
UGYR_RS06045	COG0560	Phosphoserine phosphatase
UGYR_RS06050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_RS06050	COG1263	PTS System
UGYR_RS06060	COG1737	Transcriptional regulator
UGYR_RS06065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_RS06075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
UGYR_RS06085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
UGYR_RS06100	COG0481	GTPase activity
UGYR_RS06105	COG3086	response to oxidative stress
UGYR_RS06115	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
UGYR_RS06125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
UGYR_RS06135	COG0513	Belongs to the DEAD box helicase family
UGYR_RS06150	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
UGYR_RS06160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UGYR_RS06165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
UGYR_RS06170	COG0497	DNA recombination
UGYR_RS06175	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UGYR_RS06185	COG2867	negative regulation of translational initiation
UGYR_RS06190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
UGYR_RS06195	COG0582	viral genome integration into host DNA
UGYR_RS06205	COG2963	transposase activity
UGYR_RS06225	COG2856	Zn peptidase
UGYR_RS06235	COG3596	GTP binding
UGYR_RS06240	COG2378	regulation of single-species biofilm formation
UGYR_RS06255	COG1204	response to ionizing radiation
UGYR_RS06265	COG0582	viral genome integration into host DNA
UGYR_RS06270	COG2801	Transposase and inactivated derivatives
UGYR_RS06280	COG3121	Chaperone
UGYR_RS06285	COG3188	usher protein
UGYR_RS06300	COG0583	DNA-binding transcription factor activity
UGYR_RS06340	COG2963	transposase activity
UGYR_RS06350	COG1069	ribulokinase activity
UGYR_RS06360	COG1172	Belongs to the binding-protein-dependent transport system permease family
UGYR_RS06365	COG1129	ABC transporter
UGYR_RS06385	COG1620	l-lactate permease
UGYR_RS06390	COG1304	FMN binding
UGYR_RS06395	COG0579	oxidoreductase
UGYR_RS06400	COG1278	Cold shock
UGYR_RS06430	COG1780	Probably involved in ribonucleotide reductase function
UGYR_RS06435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UGYR_RS06445	COG4175	Glycine betaine
UGYR_RS06450	COG4176	ABC-type proline glycine betaine transport system permease component
UGYR_RS06455	COG2113	Glycine betaine
UGYR_RS06465	COG2814	Major facilitator Superfamily
UGYR_RS06470	COG1846	Transcriptional regulator
UGYR_RS06480	COG1566	PFAM secretion protein HlyD family protein
UGYR_RS06485	COG2814	Major facilitator Superfamily
UGYR_RS06490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UGYR_RS06495	COG3118	belongs to the thioredoxin family
UGYR_RS06500	COG3148	PFAM DTW domain containing protein
UGYR_RS06505	COG1042	CoA-binding domain protein
UGYR_RS06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UGYR_RS06505	COG0045	succinate-CoA ligase (ADP-forming) activity
UGYR_RS06510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UGYR_RS06515	COG5544	Lipoprotein
UGYR_RS06540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UGYR_RS06550	COG2011	ABC-type metal ion transport system permease component
UGYR_RS06555	COG1464	Belongs to the NlpA lipoprotein family
UGYR_RS06565	COG1720	tRNA m6t6A37 methyltransferase activity
UGYR_RS06570	COG0442	prolyl-tRNA aminoacylation
UGYR_RS06575	COG3015	lipoprotein NlpE involved in copper resistance
UGYR_RS06585	COG4681	YaeQ
UGYR_RS06595	COG4568	rho-dependent transcription termination
UGYR_RS06610	COG0346	lactoylglutathione lyase activity
UGYR_RS06625	COG0825	malonyl-CoA metabolic process
UGYR_RS06630	COG0587	DNA-directed DNA polymerase activity
UGYR_RS06635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
UGYR_RS06655	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UGYR_RS06660	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
UGYR_RS06670	COG0750	zinc metalloprotease
UGYR_RS06675	COG0575	Belongs to the CDS family
UGYR_RS06695	COG0528	UMP kinase activity
UGYR_RS06700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
UGYR_RS06715	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
UGYR_RS06720	COG2171	N-acyltransferase activity
UGYR_RS06735	COG0564	pseudouridine synthase activity
UGYR_RS06740	COG3098	single-species biofilm formation
UGYR_RS06755	COG1611	Belongs to the LOG family
UGYR_RS06765	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
UGYR_RS06770	COG2363	Small membrane protein
UGYR_RS06775	COG0583	DNA-binding transcription factor activity
UGYR_RS06785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
UGYR_RS06790	COG2166	iron-sulfur cluster assembly
UGYR_RS06795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
UGYR_RS06800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
UGYR_RS06820	COG0860	N-Acetylmuramoyl-L-alanine amidase
UGYR_RS06825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
UGYR_RS06825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UGYR_RS06830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
UGYR_RS06835	COG1074	ATP-dependent DNA helicase activity
UGYR_RS06840	COG1025	Belongs to the peptidase M16 family
UGYR_RS06845	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
UGYR_RS06850	COG4967	type IV pilus modification protein PilV
UGYR_RS06880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
UGYR_RS06885	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
UGYR_RS06895	COG3066	DNA modification
UGYR_RS06900	COG0861	Integral membrane protein TerC family
UGYR_RS06905	COG0667	Aldo Keto reductase
UGYR_RS06910	COG0477	Major facilitator Superfamily
UGYR_RS06915	COG0318	PFAM AMP-dependent synthetase and ligase
UGYR_RS06915	COG0204	Acyl-transferase
UGYR_RS06920	COG1609	Transcriptional regulator
UGYR_RS06930	COG0583	DNA-binding transcription factor activity
UGYR_RS06935	COG0583	DNA-binding transcription factor activity
UGYR_RS06990	COG2165	general secretion pathway protein
UGYR_RS07000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UGYR_RS07030	COG1127	ABC transporter
UGYR_RS07035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UGYR_RS07045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
UGYR_RS07050	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
UGYR_RS07055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
UGYR_RS07060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UGYR_RS07065	COG4974	Belongs to the 'phage' integrase family
UGYR_RS07070	COG0716	FMN binding
UGYR_RS07080	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
UGYR_RS07090	COG1272	protein, Hemolysin III
UGYR_RS07105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
UGYR_RS07110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UGYR_RS07115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UGYR_RS07120	COG0006	proline dipeptidase activity
UGYR_RS07130	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
UGYR_RS07135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
UGYR_RS07140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UGYR_RS07145	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
UGYR_RS07160	COG1279	arginine transmembrane transporter activity
UGYR_RS07170	COG0191	fructose-bisphosphate aldolase activity
UGYR_RS07175	COG0126	phosphoglycerate kinase activity
UGYR_RS07180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
UGYR_RS07185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
UGYR_RS07195	COG1166	arginine decarboxylase activity
UGYR_RS07200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
UGYR_RS07215	COG0640	Transcriptional regulator
UGYR_RS07220	COG3091	SprT-like family
UGYR_RS07225	COG2356	endonuclease I
UGYR_RS07230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
UGYR_RS07235	COG0189	ligase activity
UGYR_RS07240	COG1678	Uncharacterized ACR, COG1678
UGYR_RS07245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
UGYR_RS07250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UGYR_RS07260	COG2805	Type II/IV secretion system protein
UGYR_RS07265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
UGYR_RS07270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
UGYR_RS07275	COG0762	integral membrane protein
UGYR_RS07280	COG1872	DUF167
UGYR_RS07285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
UGYR_RS07290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UGYR_RS07305	COG3171	Protein conserved in bacteria
UGYR_RS07315	COG1194	a g-specific adenine glycosylase
UGYR_RS07320	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
UGYR_RS07325	COG0741	lytic transglycosylase activity
UGYR_RS07350	COG3730	PTS system glucitol sorbitol-specific
UGYR_RS07355	COG3732	PTS system glucitol sorbitol-specific
UGYR_RS07360	COG3731	PTS system glucitol sorbitol-specific IIA component
UGYR_RS07365	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_RS07370	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_RS07375	COG1349	DNA-binding transcription factor activity
UGYR_RS07385	COG1105	Belongs to the carbohydrate kinase PfkB family
UGYR_RS07390	COG1882	Formate acetyltransferase
UGYR_RS07395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
UGYR_RS07400	COG0814	amino acid
UGYR_RS07415	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_RS07420	COG3433	isochorismatase activity
UGYR_RS07420	COG1535	isochorismatase
UGYR_RS07425	COG1021	2,3-dihydroxybenzoate-AMP ligase
UGYR_RS07430	COG1169	isochorismate synthase
UGYR_RS07435	COG4592	Periplasmic binding protein
UGYR_RS07445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_RS07450	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_RS07455	COG1120	ATPase activity
UGYR_RS07465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UGYR_RS07470	COG3251	PFAM MbtH domain protein
UGYR_RS07480	COG4774	siderophore transport
UGYR_RS07485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
UGYR_RS07510	COG4964	Belongs to the GSP D family
UGYR_RS07560	COG0848	biopolymer transport protein
UGYR_RS07565	COG0811	peptide transport
UGYR_RS07570	COG0626	cystathionine gamma-synthase activity
UGYR_RS07575	COG0586	Pfam SNARE associated Golgi protein
UGYR_RS07580	COG2207	Transcriptional regulator
UGYR_RS07585	COG1979	alcohol dehydrogenase
UGYR_RS07590	COG0656	L-ascorbic acid biosynthetic process
UGYR_RS07600	COG2132	Multicopper oxidase
UGYR_RS07610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
UGYR_RS07615	COG2249	NAD(P)H dehydrogenase (quinone) activity
UGYR_RS07620	COG0583	DNA-binding transcription factor activity
UGYR_RS07625	COG0187	DNA topoisomerase II activity
UGYR_RS07630	COG3150	esterase
UGYR_RS07640	COG3151	Protein conserved in bacteria
UGYR_RS07645	COG0494	nUDIX hydrolase
UGYR_RS07650	COG1538	Outer membrane efflux protein
UGYR_RS07655	COG5463	Belongs to the UPF0441 family
UGYR_RS07660	COG0754	glutathionylspermidine amidase activity
UGYR_RS07665	COG3384	dioxygenase
UGYR_RS07670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UGYR_RS07680	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
UGYR_RS07680	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
UGYR_RS07690	COG3025	triphosphatase activity
UGYR_RS07695	COG4991	sh3 domain protein
UGYR_RS07700	COG0617	tRNA 3'-terminal CCA addition
UGYR_RS07705	COG1968	undecaprenyl-diphosphatase activity
UGYR_RS07710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
UGYR_RS07715	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
UGYR_RS07720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
UGYR_RS07725	COG0828	Belongs to the bacterial ribosomal protein bS21 family
UGYR_RS07730	COG0358	DNA primase activity
UGYR_RS07755	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_RS07770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UGYR_RS07825	COG3210	domain, Protein
UGYR_RS07830	COG2831	hemolysin activation secretion protein
UGYR_RS07835	COG1902	pentaerythritol trinitrate reductase activity
UGYR_RS07835	COG0446	pyridine nucleotide-disulphide oxidoreductase
UGYR_RS07850	COG1451	nucleotide metabolic process
UGYR_RS07855	COG0673	inositol 2-dehydrogenase activity
UGYR_RS07860	COG0861	Integral membrane protein TerC family
UGYR_RS07865	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
UGYR_RS07875	COG2721	sulfolactate sulfo-lyase activity
UGYR_RS07890	COG2271	Major facilitator Superfamily
UGYR_RS07905	COG0586	Pfam SNARE associated Golgi protein
UGYR_RS07920	COG4575	ribosome binding
UGYR_RS07925	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
UGYR_RS07935	COG2259	Doxx family
UGYR_RS07940	COG0583	DNA-binding transcription factor activity
UGYR_RS07945	COG1741	Belongs to the pirin family
UGYR_RS07950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
UGYR_RS07965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
UGYR_RS07970	COG2823	Periplasmic or secreted lipoprotein
UGYR_RS07975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UGYR_RS07980	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
UGYR_RS07985	COG0784	Response regulator, receiver
UGYR_RS07985	COG2198	Histidine kinase
UGYR_RS07985	COG5002	protein histidine kinase activity
UGYR_RS07990	COG1242	4 iron, 4 sulfur cluster binding
UGYR_RS07995	COG0067	glutamate synthase
UGYR_RS07995	COG0070	glutamate synthase
UGYR_RS07995	COG0069	glutamate synthase activity
UGYR_RS08000	COG0493	'glutamate synthase
UGYR_RS08010	COG2969	positive regulation of protein catabolic process
UGYR_RS08015	COG0625	glutathione transferase activity
UGYR_RS08020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UGYR_RS08025	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
UGYR_RS08030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
UGYR_RS08035	COG3105	Protein conserved in bacteria
UGYR_RS08040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UGYR_RS08050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
UGYR_RS08055	COG5007	Belongs to the BolA IbaG family
UGYR_RS08060	COG3113	response to antibiotic
UGYR_RS08065	COG2854	intermembrane phospholipid transfer
UGYR_RS08070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
UGYR_RS08075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UGYR_RS08080	COG1127	ABC transporter
UGYR_RS08085	COG0530	calcium, potassium:sodium antiporter activity
UGYR_RS08090	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
UGYR_RS08090	COG0517	IMP dehydrogenase activity
UGYR_RS08095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
UGYR_RS08100	COG3117	lipopolysaccharide transmembrane transporter activity
UGYR_RS08105	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
UGYR_RS08110	COG1137	ATPase activity
UGYR_RS08115	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
UGYR_RS08135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_RS08140	COG0540	Belongs to the ATCase OTCase family
UGYR_RS08145	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
UGYR_RS08155	COG0366	Alpha amylase catalytic
UGYR_RS08160	COG1263	PTS System
UGYR_RS08160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_RS08170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
UGYR_RS08185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UGYR_RS08190	COG3783	Cytochrome b(562)
UGYR_RS08195	COG0312	modulator of DNA gyrase
UGYR_RS08200	COG3028	Belongs to the UPF0307 family
UGYR_RS08205	COG2732	(Barnase) inhibitor
UGYR_RS08210	COG4290	ribonuclease
UGYR_RS08220	COG1289	transmembrane transporter activity
UGYR_RS08225	COG1566	PFAM secretion protein HlyD family protein
UGYR_RS08235	COG0583	DNA-binding transcription factor activity
UGYR_RS08240	COG0312	modulator of DNA gyrase
UGYR_RS08245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UGYR_RS08250	COG3164	Protein of unknown function
UGYR_RS08260	COG0424	maF-like protein
UGYR_RS08265	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
UGYR_RS08270	COG1792	Involved in formation and maintenance of cell shape
UGYR_RS08275	COG1077	Cell shape determining protein MreB Mrl
UGYR_RS08280	COG2200	EAL domain
UGYR_RS08280	COG2199	diguanylate cyclase activity
UGYR_RS08285	COG0604	alcohol dehydrogenase
UGYR_RS08290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
UGYR_RS08295	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
UGYR_RS08305	COG0511	ligase activity, forming carbon-carbon bonds
UGYR_RS08310	COG0439	Biotin carboxylase
UGYR_RS08315	COG3924	membrane
UGYR_RS08320	COG4145	pantothenate transmembrane transporter activity
UGYR_RS08325	COG2264	protein methyltransferase activity
UGYR_RS08330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UGYR_RS08335	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
UGYR_RS08345	COG1560	Kdo2-lipid A biosynthetic process
UGYR_RS08355	COG1346	cytolysis
UGYR_RS08360	COG1380	Effector of murein hydrolase LrgA
UGYR_RS08365	COG0583	DNA-binding transcription factor activity
UGYR_RS08370	COG0025	NhaP-type Na H and K H
UGYR_RS08375	COG2252	PERMEase
UGYR_RS08390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UGYR_RS08395	COG2315	Protein conserved in bacteria
UGYR_RS08400	COG1448	Aminotransferase
UGYR_RS08415	COG0604	alcohol dehydrogenase
UGYR_RS08425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UGYR_RS08430	COG0735	belongs to the Fur family
UGYR_RS08435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
UGYR_RS08440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
UGYR_RS08445	COG2937	Belongs to the GPAT DAPAT family
UGYR_RS08465	COG4580	involved in the transport of maltose and maltodextrins
UGYR_RS08480	COG2182	Extracellular solute-binding protein
UGYR_RS08485	COG1175	transmembrane transport
UGYR_RS08490	COG3833	ABC-type maltose transport systems, permease component
UGYR_RS08495	COG3223	Belongs to the PsiE family
UGYR_RS08505	COG0527	aspartate kinase activity
UGYR_RS08520	COG3328	transposase activity
UGYR_RS08545	COG1222	aaa ATPase
UGYR_RS08620	COG0583	DNA-binding transcription factor activity
UGYR_RS08655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
UGYR_RS08695	COG0138	bifunctional purine biosynthesis protein purh
UGYR_RS08700	COG0151	Belongs to the GarS family
UGYR_RS08720	COG1515	deoxyribonuclease V activity
UGYR_RS08725	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
UGYR_RS08730	COG2816	NAD+ diphosphatase activity
UGYR_RS08735	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
UGYR_RS08750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UGYR_RS08755	COG2104	thiamine diphosphate biosynthetic process
UGYR_RS08760	COG2022	thiamine diphosphate biosynthetic process
UGYR_RS08770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
UGYR_RS08775	COG0085	RNA polymerase activity
UGYR_RS08780	COG0222	ribosome binding
UGYR_RS08785	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
UGYR_RS08795	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
UGYR_RS08800	COG0250	Participates in transcription elongation, termination and antitermination
UGYR_RS08845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
UGYR_RS08875	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
UGYR_RS08880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
UGYR_RS08885	COG1739	Uncharacterized protein family UPF0029
UGYR_RS08895	COG1250	3-hydroxyacyl-CoA dehydrogenase
UGYR_RS08895	COG1024	Enoyl-CoA hydratase
UGYR_RS08905	COG0543	2 iron, 2 sulfur cluster binding
UGYR_RS08920	COG0250	Participates in transcription elongation, termination and antitermination
UGYR_RS08935	COG0805	protein transport
UGYR_RS08945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UGYR_RS08950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
UGYR_RS08955	COG3165	ubiquinone biosynthetic process from chorismate
UGYR_RS08960	COG2226	methyltransferase
UGYR_RS08965	COG1322	Protein conserved in bacteria
UGYR_RS08970	COG0586	Pfam SNARE associated Golgi protein
UGYR_RS08975	COG1966	Carbon starvation protein
UGYR_RS08990	COG0412	Dienelactone hydrolase
UGYR_RS08995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
UGYR_RS09000	COG0583	DNA-binding transcription factor activity
UGYR_RS09005	COG0697	spore germination
UGYR_RS09015	COG0584	glycerophosphoryl diester phosphodiesterase
UGYR_RS09025	COG0395	ABC-type sugar transport system, permease component
UGYR_RS09030	COG1175	transmembrane transport
UGYR_RS09035	COG1653	transport
UGYR_RS09070	COG0410	ABC transporter
UGYR_RS09080	COG4177	L-phenylalanine transmembrane transporter activity
UGYR_RS09100	COG1929	Belongs to the glycerate kinase type-1 family
UGYR_RS09105	COG2610	gluconate transmembrane transporter activity
UGYR_RS09110	COG3835	regulator
UGYR_RS09120	COG2177	Part of the ABC transporter FtsEX involved in
UGYR_RS09125	COG2884	Cell division ATP-binding protein ftsE
UGYR_RS09130	COG0552	protein localization to endoplasmic reticulum
UGYR_RS09130	COG0552	protein localization to endoplasmic reticulum
UGYR_RS09135	COG0742	ribosomal rna small subunit methyltransferase
UGYR_RS09140	COG3776	membrane
UGYR_RS09155	COG3714	YhhN family
UGYR_RS09170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
UGYR_RS09180	COG0247	lactate metabolic process
UGYR_RS09190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UGYR_RS09200	COG2271	Major facilitator Superfamily
UGYR_RS09205	COG0584	glycerophosphoryl diester phosphodiesterase
UGYR_RS09210	COG0561	phosphatase activity
UGYR_RS09215	COG2267	carboxylic ester hydrolase activity
UGYR_RS09220	COG1280	lysine exporter protein (LysE YggA)
UGYR_RS09225	COG0514	ATP-dependent DNA helicase (RecQ)
UGYR_RS09230	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
UGYR_RS09235	COG2050	protein possibly involved in aromatic compounds catabolism
UGYR_RS09255	COG5564	TIM-barrel signal transduction protein
UGYR_RS09260	COG5441	Belongs to the UPF0261 family
UGYR_RS09270	COG0210	DNA helicase
UGYR_RS09275	COG1011	Hydrolase
UGYR_RS09280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
UGYR_RS09285	COG3159	Protein conserved in bacteria
UGYR_RS09290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
UGYR_RS09295	COG5567	small periplasmic lipoprotein
UGYR_RS09305	COG3072	Adenylate cyclase
UGYR_RS09310	COG0181	hydroxymethylbilane synthase activity
UGYR_RS09315	COG1587	Uroporphyrinogen-III synthase
UGYR_RS09320	COG2959	enzyme of heme biosynthesis
UGYR_RS09325	COG3071	HemY protein
UGYR_RS09375	COG2244	polysaccharide biosynthetic process
UGYR_RS09380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UGYR_RS09385	COG0456	acetyltransferase
UGYR_RS09390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
UGYR_RS09395	COG1088	dTDP-glucose 4,6-dehydratase activity
UGYR_RS09400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
UGYR_RS09405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
UGYR_RS09410	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
UGYR_RS09415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
UGYR_RS09420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
UGYR_RS09425	COG3118	belongs to the thioredoxin family
UGYR_RS09435	COG0248	Ppx GppA phosphatase
UGYR_RS09445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UGYR_RS09460	COG3397	chitin binding
UGYR_RS09470	COG0129	dihydroxy-acid dehydratase activity
UGYR_RS09480	COG3978	acetolactate synthase activity
UGYR_RS09495	COG3085	chromosome segregation
UGYR_RS09500	COG0583	DNA-binding transcription factor activity
UGYR_RS09570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UGYR_RS09580	COG0678	peroxiredoxin activity
UGYR_RS09580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
UGYR_RS09585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UGYR_RS09620	COG1629	transport
UGYR_RS09625	COG0165	Argininosuccinate lyase
UGYR_RS09630	COG0137	argininosuccinate synthase activity
UGYR_RS09635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UGYR_RS09675	COG0527	aspartate kinase activity
UGYR_RS09675	COG0460	homoserine dehydrogenase
UGYR_RS09680	COG0626	cystathionine gamma-synthase activity
UGYR_RS09685	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
UGYR_RS09695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
UGYR_RS09700	COG1609	Transcriptional regulator
UGYR_RS09705	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
UGYR_RS09710	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
UGYR_RS09715	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
UGYR_RS09720	COG1575	Belongs to the MenA family. Type 1 subfamily
UGYR_RS09725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
UGYR_RS09730	COG3074	FtsZ-dependent cytokinesis
UGYR_RS09735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
UGYR_RS09740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
UGYR_RS09745	COG1494	fructose-1,6-bisphosphatase
UGYR_RS09750	COG2814	Major facilitator Superfamily
UGYR_RS09760	COG3152	Membrane
UGYR_RS09775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
UGYR_RS09785	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
UGYR_RS09790	COG3678	ATP-independent chaperone mediated protein folding
UGYR_RS09795	COG0745	RESPONSE REGULATOR receiver
UGYR_RS09800	COG2205	protein histidine kinase activity
UGYR_RS09805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
UGYR_RS09810	COG1045	serine acetyltransferase
UGYR_RS09815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
UGYR_RS09820	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
UGYR_RS09825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
UGYR_RS09830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
UGYR_RS09835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
UGYR_RS09840	COG4942	peptidase
UGYR_RS09845	COG2861	carbohydrate metabolic process
UGYR_RS09860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UGYR_RS09865	COG0859	PFAM glycosyl transferase family 9
UGYR_RS09870	COG0859	PFAM glycosyl transferase family 9
UGYR_RS09875	COG1519	Transferase
UGYR_RS09895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UGYR_RS09900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
UGYR_RS09905	COG2003	Belongs to the UPF0758 family
UGYR_RS09910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
UGYR_RS09915	COG0756	dUTP diphosphatase activity
UGYR_RS09920	COG1309	transcriptional regulator
UGYR_RS09925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
UGYR_RS09930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
UGYR_RS09935	COG1561	YicC-like family, N-terminal region
UGYR_RS09950	COG5001	Diguanylate cyclase
UGYR_RS09965	COG5001	Diguanylate cyclase
UGYR_RS09970	COG1024	Enoyl-CoA hydratase
UGYR_RS09975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
UGYR_RS09985	COG2860	membrane
UGYR_RS09990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UGYR_RS10000	COG1758	RNA polymerase activity
UGYR_RS10005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UGYR_RS10010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UGYR_RS10015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
UGYR_RS10020	COG0786	glutamate:sodium symporter activity
UGYR_RS10025	COG2233	PERMEase
UGYR_RS10030	COG2982	Protein involved in outer membrane biogenesis
UGYR_RS10035	COG0456	acetyltransferase
UGYR_RS10050	COG1011	Hydrolase
UGYR_RS10065	COG3852	Histidine kinase
UGYR_RS10075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UGYR_RS10085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
UGYR_RS10090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UGYR_RS10090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UGYR_RS10095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UGYR_RS10100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
UGYR_RS10105	COG3084	Protein conserved in bacteria
UGYR_RS10115	COG1763	Mo-molybdopterin cofactor biosynthetic process
UGYR_RS10140	COG2186	Transcriptional regulator
UGYR_RS10145	COG1609	Transcriptional regulator
UGYR_RS10150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UGYR_RS10160	COG1172	Belongs to the binding-protein-dependent transport system permease family
UGYR_RS10165	COG1129	ABC transporter
UGYR_RS10170	COG1869	D-ribose catabolic process
UGYR_RS10175	COG3158	transport of potassium into the cell
UGYR_RS10180	COG0714	Associated with various cellular activities
UGYR_RS10185	COG2425	protein containing a von Willebrand factor type A (vWA) domain
UGYR_RS10195	COG2502	aspartate--ammonia ligase
UGYR_RS10200	COG1522	sequence-specific DNA binding
UGYR_RS10205	COG0716	FMN binding
UGYR_RS10210	COG0445	tRNA wobble uridine modification
UGYR_RS10215	COG0357	Ribosomal RNA small subunit methyltransferase G
UGYR_RS10220	COG3312	ion transport
UGYR_RS10225	COG0356	it plays a direct role in the translocation of protons across the membrane
UGYR_RS10235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
UGYR_RS10245	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
UGYR_RS10250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
UGYR_RS10260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
UGYR_RS10275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
UGYR_RS10280	COG0573	inorganic phosphate transmembrane transporter activity
UGYR_RS10285	COG0581	inorganic phosphate transmembrane transporter activity
UGYR_RS10295	COG0704	Plays a role in the regulation of phosphate uptake
UGYR_RS10300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_RS10305	COG0765	amino acid transport
UGYR_RS10310	COG0765	amino acid transport
UGYR_RS10315	COG2252	PERMEase
UGYR_RS10320	COG0840	transmembrane signaling receptor activity
UGYR_RS10330	COG3121	Chaperone
UGYR_RS10345	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
UGYR_RS10350	COG0706	membrane insertase activity
UGYR_RS10360	COG0594	ribonuclease P activity
UGYR_RS10365	COG0230	Belongs to the bacterial ribosomal protein bL34 family
UGYR_RS10375	COG0592	DNA-directed DNA polymerase activity
UGYR_RS10385	COG0187	DNA topoisomerase II activity
UGYR_RS10390	COG0561	phosphatase activity
UGYR_RS10395	COG0823	Involved in the tonB-independent uptake of proteins
UGYR_RS10400	COG5645	(Lipo)protein
UGYR_RS10415	COG2985	domain, Protein
UGYR_RS10415	COG0569	domain protein
UGYR_RS10420	COG3977	Valine--pyruvate aminotransferase
UGYR_RS10425	COG2885	chlorophyll binding
UGYR_RS10445	COG2818	Glycosylase
UGYR_RS10495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_RS10495	COG2213	PTS system mannitol-specific
UGYR_RS10505	COG3722	fumarate hydratase activity
UGYR_RS10515	COG2258	MOSC domain
UGYR_RS10520	COG0840	transmembrane signaling receptor activity
UGYR_RS10525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UGYR_RS10535	COG0243	molybdopterin cofactor binding
UGYR_RS10535	COG3383	formate dehydrogenase (NAD+) activity
UGYR_RS10540	COG0243	molybdopterin cofactor binding
UGYR_RS10540	COG3383	formate dehydrogenase (NAD+) activity
UGYR_RS10545	COG0437	4 iron, 4 sulfur cluster binding
UGYR_RS10550	COG2864	formate dehydrogenase
UGYR_RS10560	COG1921	L-seryl-tRNASec selenium transferase activity
UGYR_RS10565	COG3276	selenocysteine insertion sequence binding
UGYR_RS10570	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
UGYR_RS10580	COG3274	enterobacterial common antigen metabolic process
UGYR_RS10585	COG2801	Transposase and inactivated derivatives
UGYR_RS10610	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
UGYR_RS10615	COG2986	histidine ammonia-lyase
UGYR_RS10635	COG2194	sulfuric ester hydrolase activity
UGYR_RS10640	COG2197	response regulator
UGYR_RS10645	COG3851	Histidine kinase
UGYR_RS10650	COG2271	Major facilitator Superfamily
UGYR_RS10660	COG0747	negative chemotaxis
UGYR_RS10665	COG0601	transmembrane transport
UGYR_RS10670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UGYR_RS10675	COG0444	Belongs to the ABC transporter superfamily
UGYR_RS10680	COG4608	Belongs to the ABC transporter superfamily
UGYR_RS10685	COG2194	sulfuric ester hydrolase activity
UGYR_RS10710	COG1215	transferase activity, transferring glycosyl groups
UGYR_RS10715	COG1215	transferase activity, transferring glycosyl groups
UGYR_RS10720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
UGYR_RS10725	COG0457	Tetratricopeptide repeat
UGYR_RS10725	COG3118	belongs to the thioredoxin family
UGYR_RS10730	COG2200	EAL domain
UGYR_RS10730	COG2199	diguanylate cyclase activity
UGYR_RS10735	COG1301	dicarboxylic acid transport
UGYR_RS10740	COG0612	Peptidase, M16
UGYR_RS10745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UGYR_RS10750	COG1942	4-Oxalocrotonate Tautomerase
UGYR_RS10755	COG2200	EAL domain
UGYR_RS10760	COG2134	cdp-diacylglycerol pyrophosphatase
UGYR_RS10765	COG1295	ribonuclease BN
UGYR_RS10775	COG1301	dicarboxylic acid transport
UGYR_RS10780	COG0626	cystathionine gamma-synthase activity
UGYR_RS10785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UGYR_RS10790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
UGYR_RS10795	COG0339	signal peptide processing
UGYR_RS10800	COG0742	ribosomal rna small subunit methyltransferase
UGYR_RS10810	COG0589	response to stress
UGYR_RS10820	COG0306	phosphate transporter
UGYR_RS10825	COG2081	HI0933 family
UGYR_RS10835	COG1247	-acetyltransferase
UGYR_RS10840	COG1741	Belongs to the pirin family
UGYR_RS10845	COG1609	Transcriptional regulator
UGYR_RS10850	COG2610	gluconate transmembrane transporter activity
UGYR_RS10855	COG3265	gluconokinase activity
UGYR_RS10860	COG2095	MarC family integral membrane protein
UGYR_RS10865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UGYR_RS10870	COG3275	phosphorelay sensor kinase activity
UGYR_RS10875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
UGYR_RS10880	COG1523	belongs to the glycosyl hydrolase 13 family
UGYR_RS10885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
UGYR_RS10890	COG0297	glycogen (starch) synthase activity
UGYR_RS10895	COG0058	SHG alpha-glucan phosphorylase activity
UGYR_RS10900	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UGYR_RS10905	COG1349	DNA-binding transcription factor activity
UGYR_RS10910	COG0705	Rhomboid family
UGYR_RS10920	COG2909	trisaccharide binding
UGYR_RS10925	COG0058	SHG alpha-glucan phosphorylase activity
UGYR_RS10930	COG1640	4-alpha-glucanotransferase
UGYR_RS10940	COG1040	competence protein
UGYR_RS10945	COG0596	Alpha beta hydrolase
UGYR_RS10965	COG1918	ferrous iron import across plasma membrane
UGYR_RS10970	COG2183	response to ionizing radiation
UGYR_RS10995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UGYR_RS11010	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
UGYR_RS11020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
UGYR_RS11025	COG1011	Hydrolase
UGYR_RS11035	COG0494	nUDIX hydrolase
UGYR_RS11040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
UGYR_RS11065	COG4796	Type ii and iii secretion system protein
UGYR_RS11070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
UGYR_RS11090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
UGYR_RS11100	COG0180	Tryptophanyl-tRNA synthetase
UGYR_RS11120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UGYR_RS11125	COG0402	S-adenosylhomocysteine deaminase activity
UGYR_RS11130	COG0738	Major facilitator superfamily
UGYR_RS11145	COG1609	Transcriptional regulator
UGYR_RS11150	COG1486	melibiose metabolic process
UGYR_RS11160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UGYR_RS11175	COG1289	transmembrane transporter activity
UGYR_RS11180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UGYR_RS11185	COG1765	OsmC-like protein
UGYR_RS11210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UGYR_RS11215	COG3954	Phosphoribulokinase
UGYR_RS11225	COG0429	hydrolase of the alpha beta-hydrolase fold
UGYR_RS11235	COG0859	PFAM glycosyl transferase family 9
UGYR_RS11240	COG1216	Glycosyl transferase, family 2
UGYR_RS11245	COG0488	(ABC) transporter
UGYR_RS11250	COG2249	NAD(P)H dehydrogenase (quinone) activity
UGYR_RS11260	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
UGYR_RS11265	COG1047	Peptidyl-prolyl cis-trans
UGYR_RS11275	COG0545	Peptidyl-prolyl cis-trans isomerase
UGYR_RS11280	COG2964	Protein conserved in bacteria
UGYR_RS11290	COG2923	Belongs to the DsrF TusC family
UGYR_RS11295	COG2168	tRNA wobble position uridine thiolation
UGYR_RS11300	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
UGYR_RS11305	COG0049	tRNA binding
UGYR_RS11315	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UGYR_RS11325	COG0051	transcription antitermination factor activity, RNA binding
UGYR_RS11330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
UGYR_RS11340	COG0089	rRNA binding
UGYR_RS11345	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UGYR_RS11350	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
UGYR_RS11355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
UGYR_RS11365	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
UGYR_RS11370	COG0255	Belongs to the universal ribosomal protein uL29 family
UGYR_RS11375	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
UGYR_RS11380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
UGYR_RS11390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
UGYR_RS11415	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
UGYR_RS11420	COG1841	ribosomal large subunit assembly
UGYR_RS11425	COG0200	Binds to the 23S rRNA
UGYR_RS11430	COG0201	protein transport
UGYR_RS11435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
UGYR_RS11440	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
UGYR_RS11450	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
UGYR_RS11460	COG0203	ribosomal protein L17
UGYR_RS11465	COG0789	Transcriptional regulator
UGYR_RS11470	COG3036	rescue of stalled ribosome
UGYR_RS11475	COG1970	mechanosensitive ion channel activity
UGYR_RS11485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
UGYR_RS11485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UGYR_RS11490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
UGYR_RS11495	COG0242	peptide deformylase activity
UGYR_RS11500	COG0758	DNA mediated transformation
UGYR_RS11505	COG2922	Belongs to the Smg family
UGYR_RS11510	COG0009	L-threonylcarbamoyladenylate synthase
UGYR_RS11520	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
UGYR_RS11550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UGYR_RS11555	COG3162	membrane
UGYR_RS11560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
UGYR_RS11565	COG1301	dicarboxylic acid transport
UGYR_RS11575	COG1309	transcriptional regulator
UGYR_RS11580	COG4232	protein-disulfide reductase activity
UGYR_RS11590	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
UGYR_RS11620	COG1509	lysine 2,3-aminomutase activity
UGYR_RS11630	COG3397	chitin binding
UGYR_RS11650	COG3188	usher protein
UGYR_RS11670	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
UGYR_RS11675	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
UGYR_RS11680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UGYR_RS11685	COG1053	succinate dehydrogenase
UGYR_RS11690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
UGYR_RS11695	COG3264	Mechanosensitive ion channel
UGYR_RS11695	COG1511	domain protein
UGYR_RS11700	COG0688	phosphatidylethanolamine metabolic process
UGYR_RS11705	COG1162	GTPase activity
UGYR_RS11710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
UGYR_RS11730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
UGYR_RS11735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
UGYR_RS11735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
UGYR_RS11740	COG0802	atpase or kinase
UGYR_RS11745	COG0860	N-Acetylmuramoyl-L-alanine amidase
UGYR_RS11755	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
UGYR_RS11765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
UGYR_RS11770	COG0330	HflC and HflK could
UGYR_RS11775	COG0330	HflC and HflK could
UGYR_RS11780	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
UGYR_RS11785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
UGYR_RS11790	COG1959	2 iron, 2 sulfur cluster binding
UGYR_RS11795	COG0557	exoribonuclease II activity
UGYR_RS11800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UGYR_RS11820	COG3121	Chaperone
UGYR_RS11825	COG3188	usher protein
UGYR_RS11845	COG1073	alpha beta
UGYR_RS11855	COG0360	Binds together with S18 to 16S ribosomal RNA
UGYR_RS11860	COG2965	DNA replication, synthesis of RNA primer
UGYR_RS11865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
UGYR_RS11870	COG0359	binds to the 23S rRNA
UGYR_RS11875	COG3061	Opacity-associated protein A
UGYR_RS11880	COG0545	Peptidyl-prolyl cis-trans isomerase
UGYR_RS11890	COG0737	Belongs to the 5'-nucleotidase family
UGYR_RS11895	COG1218	3'(2'),5'-bisphosphate nucleotidase
UGYR_RS11900	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
UGYR_RS11910	COG1253	flavin adenine dinucleotide binding
UGYR_RS11915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UGYR_RS11920	COG0729	surface antigen
UGYR_RS11925	COG2911	Protein conserved in bacteria
UGYR_RS11930	COG2105	PFAM AIG2 family protein
UGYR_RS11935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
UGYR_RS11945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UGYR_RS11960	COG3423	Transcriptional regulator
UGYR_RS11975	COG0142	geranyltranstransferase activity
UGYR_RS11990	COG0697	spore germination
UGYR_RS11995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UGYR_RS12000	COG0642	Histidine kinase
UGYR_RS12005	COG0745	RESPONSE REGULATOR receiver
UGYR_RS12010	COG2027	D-alanyl-D-alanine carboxypeptidase
UGYR_RS12020	COG1534	Rna-binding protein
UGYR_RS12025	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
UGYR_RS12035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
UGYR_RS12040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UGYR_RS12045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
UGYR_RS12065	COG0195	Participates in both transcription termination and antitermination
UGYR_RS12075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
UGYR_RS12090	COG1185	polyribonucleotide nucleotidyltransferase activity
UGYR_RS12100	COG0513	Belongs to the DEAD box helicase family
UGYR_RS12105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UGYR_RS12110	COG0814	amino acid
UGYR_RS12120	COG0826	peptidase U32
UGYR_RS12125	COG0826	peptidase U32
UGYR_RS12130	COG3154	lipid carrier protein
UGYR_RS12135	COG3153	acetyltransferase
UGYR_RS12140	COG2827	Endonuclease containing a URI domain
UGYR_RS12145	COG0531	amino acid
UGYR_RS12150	COG1982	Orn Lys Arg decarboxylase major
UGYR_RS12160	COG3787	Belongs to the UPF0306 family
UGYR_RS12165	COG0702	epimerase
UGYR_RS12170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
UGYR_RS12175	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
UGYR_RS12180	COG3454	Phosphonate metabolism
UGYR_RS12185	COG4778	phosphonate C-P lyase system protein PhnL
UGYR_RS12190	COG4107	phosphonate C-P lyase system protein PhnK
UGYR_RS12195	COG3627	carbon phosphorus lyase activity
UGYR_RS12200	COG3626	phosphonate metabolism
UGYR_RS12205	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
UGYR_RS12210	COG3624	Phosphonate C-P lyase system protein PhnG
UGYR_RS12230	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
UGYR_RS12245	COG2927	DNA polymerase III (CHI subunit)
UGYR_RS12250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
UGYR_RS12255	COG0795	lipopolysaccharide-transporting ATPase activity
UGYR_RS12260	COG0795	lipopolysaccharide-transporting ATPase activity
UGYR_RS12270	COG0582	viral genome integration into host DNA
UGYR_RS12275	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
UGYR_RS12295	COG1196	nuclear chromosome segregation
UGYR_RS12305	COG1401	restriction endodeoxyribonuclease activity
UGYR_RS12390	COG2801	Transposase and inactivated derivatives
UGYR_RS12460	COG3077	Addiction module antitoxin, RelB DinJ family
UGYR_RS12490	COG2801	Transposase and inactivated derivatives
UGYR_RS12525	COG5492	domain, Protein
UGYR_RS12545	COG3119	arylsulfatase activity
UGYR_RS12555	COG1349	DNA-binding transcription factor activity
UGYR_RS12565	COG2222	sugar isomerase
UGYR_RS12570	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_RS12575	COG3715	PTS system
UGYR_RS12580	COG3716	PTS system mannose fructose sorbose family IID component
UGYR_RS12590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
UGYR_RS12600	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_RS12610	COG0641	radical SAM
UGYR_RS12615	COG3119	arylsulfatase activity
UGYR_RS12640	COG0859	PFAM glycosyl transferase family 9
UGYR_RS12655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_RS12660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UGYR_RS12670	COG2376	Dihydroxyacetone kinase
UGYR_RS12675	COG1461	Dihydroxyacetone kinase
UGYR_RS12680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_RS12680	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
UGYR_RS12680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UGYR_RS12720	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
UGYR_RS12735	COG2823	Periplasmic or secreted lipoprotein
UGYR_RS12740	COG4667	esterase of the alpha-beta hydrolase superfamily
UGYR_RS12745	COG0084	hydrolase, TatD family'
UGYR_RS12750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
UGYR_RS12765	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
UGYR_RS12775	COG3726	membrane protein affecting hemolysin expression
UGYR_RS12780	COG0560	Phosphoserine phosphatase
UGYR_RS12795	COG0488	(ABC) transporter
UGYR_RS12800	COG2885	chlorophyll binding
UGYR_RS12815	COG0741	lytic transglycosylase activity
UGYR_RS12820	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
UGYR_RS12825	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
UGYR_RS12830	COG0406	alpha-ribazole phosphatase activity
UGYR_RS12835	COG2207	Transcriptional regulator
UGYR_RS12835	COG3708	Transcriptional regulator
UGYR_RS12840	COG3045	CreA protein
UGYR_RS12845	COG0745	RESPONSE REGULATOR receiver
UGYR_RS12870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
UGYR_RS12875	COG0521	Mo-molybdopterin cofactor biosynthetic process
UGYR_RS12880	COG0477	Major facilitator Superfamily
UGYR_RS12890	COG1584	GPR1 FUN34 yaaH family protein
UGYR_RS12895	COG0443	Heat shock 70 kDa protein
UGYR_RS12905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
UGYR_RS12910	COG0583	DNA-binding transcription factor activity
UGYR_RS12920	COG0196	riboflavin kinase activity
UGYR_RS12930	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UGYR_RS12935	COG1047	Peptidyl-prolyl cis-trans
UGYR_RS12940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
UGYR_RS12955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
UGYR_RS12965	COG2966	Psort location CytoplasmicMembrane, score
UGYR_RS12990	COG2967	ApaG domain
UGYR_RS12995	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
UGYR_RS13000	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UGYR_RS13010	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
UGYR_RS13020	COG0564	pseudouridine synthase activity
UGYR_RS13025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UGYR_RS13030	COG0417	DNA replication proofreading
UGYR_RS13035	COG0586	Pfam SNARE associated Golgi protein
UGYR_RS13045	COG1178	ABC-type Fe3 transport system permease component
UGYR_RS13050	COG4143	(ABC) transporter
UGYR_RS13060	COG2814	Major facilitator Superfamily
UGYR_RS13070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
UGYR_RS13075	COG0473	3-isopropylmalate dehydrogenase activity
UGYR_RS13090	COG1022	Amp-dependent synthetase and ligase
UGYR_RS13095	COG0028	Belongs to the TPP enzyme family
UGYR_RS13115	COG0675	Transposase, IS605 OrfB family
UGYR_RS13130	COG0275	rRNA processing
UGYR_RS13135	COG3116	cell division
UGYR_RS13140	COG0768	penicillin binding
UGYR_RS13145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
UGYR_RS13150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
UGYR_RS13165	COG0772	Belongs to the SEDS family
UGYR_RS13170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
UGYR_RS13175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UGYR_RS13185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
UGYR_RS13190	COG0849	cell division
UGYR_RS13195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
UGYR_RS13220	COG0494	nUDIX hydrolase
UGYR_RS13240	COG0516	GMP reductase activity
UGYR_RS13245	COG1459	type II secretion system
UGYR_RS13250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UGYR_RS13255	COG4969	Belongs to the N-Me-Phe pilin family
UGYR_RS13270	COG3725	Membrane protein required for beta-lactamase induction
UGYR_RS13275	COG1113	amino acid transport
UGYR_RS13280	COG2186	Transcriptional regulator
UGYR_RS13285	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
UGYR_RS13290	COG0508	dehydrogenase complex catalyzes the overall conversion of
UGYR_RS13295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UGYR_RS13305	COG1049	propionate catabolic process, 2-methylcitrate cycle
UGYR_RS13310	COG3112	Uncharacterised protein family (UPF0231)
UGYR_RS13325	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
UGYR_RS13335	COG2132	Multicopper oxidase
UGYR_RS13345	COG0288	reversible hydration of carbon dioxide
UGYR_RS13350	COG1131	(ABC) transporter
UGYR_RS13355	COG0842	Transport permease protein
UGYR_RS13360	COG0726	polysaccharide deacetylase
UGYR_RS13365	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
UGYR_RS13370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
UGYR_RS13375	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
UGYR_RS13380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
UGYR_RS13385	COG0617	tRNA 3'-terminal CCA addition
UGYR_RS13400	COG1489	DNA binding
UGYR_RS13405	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
UGYR_RS13410	COG1643	Atp-dependent helicase
UGYR_RS13415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UGYR_RS13420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
UGYR_RS13430	COG0316	Belongs to the HesB IscA family
UGYR_RS13435	COG2860	membrane
UGYR_RS13445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
UGYR_RS13450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
UGYR_RS13455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UGYR_RS13465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UGYR_RS13470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UGYR_RS13475	COG3956	TIGRFAM MazG family protein
UGYR_RS13480	COG0504	CTP synthase activity
UGYR_RS13490	COG0602	queuosine metabolic process
UGYR_RS13495	COG0720	synthase
UGYR_RS13500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
UGYR_RS13525	COG2234	aminopeptidase activity
UGYR_RS13530	COG1648	precorrin-2 dehydrogenase activity
UGYR_RS13530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
UGYR_RS13535	COG0175	sulfate reduction
UGYR_RS13540	COG2895	sulfate adenylyltransferase (ATP) activity
UGYR_RS13545	COG0529	Catalyzes the synthesis of activated sulfate
UGYR_RS13555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
UGYR_RS13565	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
UGYR_RS13570	COG0585	pseudouridine synthase activity
UGYR_RS13575	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
UGYR_RS13585	COG4942	peptidase
UGYR_RS13585	COG1388	LysM domain
UGYR_RS13590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UGYR_RS13595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
UGYR_RS13655	COG0784	Response regulator, receiver
UGYR_RS13655	COG2205	protein histidine kinase activity
UGYR_RS13675	COG0741	lytic transglycosylase activity
UGYR_RS13805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UGYR_RS13825	COG3397	chitin binding
UGYR_RS13835	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
UGYR_RS13880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UGYR_RS13890	COG3031	protein transport across the cell outer membrane
UGYR_RS13915	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
UGYR_RS13915	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
UGYR_RS13930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
UGYR_RS13935	COG2137	regulation of response to DNA damage stimulus
UGYR_RS13940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
UGYR_RS13945	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
UGYR_RS13970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UGYR_RS13975	COG1238	metal cluster binding
UGYR_RS13980	COG2918	glutathione biosynthetic process
UGYR_RS13985	COG1854	S-ribosylhomocysteine lyase activity
UGYR_RS13990	COG4536	flavin adenine dinucleotide binding
UGYR_RS13995	COG4137	Cytochrome C assembly protein
UGYR_RS14000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
UGYR_RS14010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
UGYR_RS14015	COG0336	Belongs to the RNA methyltransferase TrmD family
UGYR_RS14020	COG0335	large ribosomal subunit rRNA binding
UGYR_RS14025	COG3137	Salt-induced outer membrane protein
UGYR_RS14030	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
UGYR_RS14035	COG3279	Response regulator of the LytR AlgR family
UGYR_RS14040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UGYR_RS14045	COG0287	Prephenate dehydrogenase
UGYR_RS14045	COG1605	Chorismate mutase
UGYR_RS14050	COG1605	Chorismate mutase
UGYR_RS14050	COG0077	Prephenate dehydratase
UGYR_RS14055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
UGYR_RS14060	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UGYR_RS14065	COG0564	pseudouridine synthase activity
UGYR_RS14070	COG1496	oxidoreductase activity
UGYR_RS14110	COG3021	interspecies interaction between organisms
UGYR_RS14115	COG1388	LysM domain
UGYR_RS14115	COG0741	lytic transglycosylase activity
UGYR_RS14125	COG2226	methyltransferase
UGYR_RS14135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
UGYR_RS14145	COG1960	acyl-CoA dehydrogenase activity
UGYR_RS14150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
UGYR_RS14155	COG0121	glutamine amidotransferase
UGYR_RS14160	COG3034	peptidoglycan biosynthetic process
UGYR_RS14170	COG1805	sodium ion transport
UGYR_RS14175	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UGYR_RS14180	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UGYR_RS14185	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UGYR_RS14195	COG1477	protein flavinylation
UGYR_RS14200	COG2991	Protein conserved in bacteria
UGYR_RS14210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
UGYR_RS14215	COG2195	Cleaves the N-terminal amino acid of tripeptides
UGYR_RS14220	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
UGYR_RS14225	COG1073	alpha beta
UGYR_RS14240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
UGYR_RS14275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
UGYR_RS14295	COG4126	flavin adenine dinucleotide binding
UGYR_RS14305	COG2974	May be involved in recombination
UGYR_RS14310	COG1940	carbohydrate kinase activity
UGYR_RS14315	COG0419	ATPase involved in DNA repair
UGYR_RS14325	COG0745	RESPONSE REGULATOR receiver
UGYR_RS14330	COG5002	protein histidine kinase activity
UGYR_RS14345	COG1113	amino acid transport
UGYR_RS14350	COG0366	Alpha amylase catalytic
UGYR_RS14355	COG0300	oxidoreductase activity
UGYR_RS14360	COG0450	alkyl hydroperoxide reductase
UGYR_RS14365	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
UGYR_RS14380	COG1862	Preprotein translocase
UGYR_RS14385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UGYR_RS14390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UGYR_RS14395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
UGYR_RS14400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UGYR_RS14400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UGYR_RS14405	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
UGYR_RS14415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
UGYR_RS14420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
UGYR_RS14425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
UGYR_RS14430	COG0142	geranyltranstransferase activity
UGYR_RS14465	COG0693	protein deglycase activity
UGYR_RS14470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
UGYR_RS14475	COG1666	GTP binding
UGYR_RS14480	COG2814	Major facilitator Superfamily
UGYR_RS14490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
UGYR_RS14495	COG1845	cytochrome c oxidase, subunit III
UGYR_RS14500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
UGYR_RS14505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
UGYR_RS14515	COG2223	nitrite transmembrane transporter activity
UGYR_RS14520	COG3056	Lipoprotein
UGYR_RS14525	COG0271	Belongs to the BolA IbaG family
UGYR_RS14535	COG0740	serine-type endopeptidase activity
UGYR_RS14540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
UGYR_RS14545	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
UGYR_RS14550	COG0776	regulation of translation
UGYR_RS14555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UGYR_RS14560	COG1555	photosystem II stabilization
UGYR_RS14565	COG0824	Thioesterase
UGYR_RS14570	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
UGYR_RS14575	COG4533	DNA binding
UGYR_RS14590	COG1522	sequence-specific DNA binding
UGYR_RS14595	COG1132	(ABC) transporter
UGYR_RS14600	COG1132	(ABC) transporter
UGYR_RS14605	COG0347	Belongs to the P(II) protein family
UGYR_RS14610	COG0004	ammonium transporteR
UGYR_RS14615	COG1946	Acyl-CoA thioesterase
UGYR_RS14620	COG3695	enzyme binding
UGYR_RS14640	COG0254	rRNA binding
UGYR_RS14645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UGYR_RS14650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_RS14655	COG1309	transcriptional regulator
UGYR_RS14660	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
UGYR_RS14665	COG1196	nuclear chromosome segregation
UGYR_RS14665	COG3264	Mechanosensitive ion channel
UGYR_RS14675	COG2832	Protein of unknown function (DUF454)
UGYR_RS14680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
UGYR_RS14720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
UGYR_RS14725	COG0326	Molecular chaperone. Has ATPase activity
UGYR_RS14740	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
UGYR_RS14745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UGYR_RS14750	COG4651	solute:proton antiporter activity
UGYR_RS14750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UGYR_RS14755	COG0737	Belongs to the 5'-nucleotidase family
UGYR_RS14770	COG0500	methyltransferase
UGYR_RS14795	COG1086	Polysaccharide biosynthesis protein
UGYR_RS14810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
UGYR_RS14815	COG3735	TraB family
UGYR_RS14820	COG2217	Heavy metal translocating P-type atpase
UGYR_RS14825	COG0789	Transcriptional regulator
UGYR_RS14830	COG1585	Membrane protein implicated in regulation of membrane protease activity
UGYR_RS14835	COG0330	HflC and HflK could
UGYR_RS14840	COG3118	belongs to the thioredoxin family
UGYR_RS14845	COG0300	oxidoreductase activity
UGYR_RS14850	COG2755	lipolytic protein G-D-S-L family
UGYR_RS14855	COG4181	ATPase activity
UGYR_RS14860	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
UGYR_RS14865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
UGYR_RS14870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
UGYR_RS14880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UGYR_RS14905	COG3188	usher protein
UGYR_RS14910	COG3121	Chaperone
UGYR_RS14940	COG2501	S4 domain
UGYR_RS14945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
UGYR_RS14960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
UGYR_RS14965	COG1393	Belongs to the ArsC family
UGYR_RS14975	COG1022	Amp-dependent synthetase and ligase
UGYR_RS15000	COG3038	cytochrome b561
UGYR_RS15030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
UGYR_RS15040	COG1215	transferase activity, transferring glycosyl groups
UGYR_RS15060	COG3250	beta-galactosidase activity
UGYR_RS15075	COG1309	transcriptional regulator
UGYR_RS15100	COG2197	response regulator
UGYR_RS15105	COG1278	Cold shock
UGYR_RS15125	COG3706	GGDEF domain
UGYR_RS15135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
UGYR_RS15145	COG2921	Belongs to the UPF0250 family
UGYR_RS15150	COG1686	Belongs to the peptidase S11 family
UGYR_RS15155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
UGYR_RS15160	COG0772	Belongs to the SEDS family
UGYR_RS15165	COG0768	penicillin binding
UGYR_RS15170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
UGYR_RS15175	COG0799	negative regulation of ribosome biogenesis
UGYR_RS15180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
UGYR_RS15185	COG1466	dna polymerase III delta subunit
UGYR_RS15190	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
UGYR_RS15200	COG2888	peptidyl-tyrosine sulfation
UGYR_RS15205	COG1126	abc transporter atp-binding protein
UGYR_RS15210	COG0765	amino acid transport
UGYR_RS15215	COG0765	amino acid transport
UGYR_RS15230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
UGYR_RS15235	COG4535	Mg2 and Co2 transporter CorC
UGYR_RS15240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
UGYR_RS15245	COG1702	phosphate starvation-inducible protein PhoH
UGYR_RS15250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UGYR_RS15255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UGYR_RS15290	COG0367	asparagine synthase
UGYR_RS15295	COG0647	UMP catabolic process
UGYR_RS15300	COG1846	Transcriptional regulator
UGYR_RS15300	COG1940	carbohydrate kinase activity
UGYR_RS15305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
UGYR_RS15315	COG2190	(PTS) system
UGYR_RS15315	COG1263	PTS System
UGYR_RS15315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_RS15340	COG0735	belongs to the Fur family
UGYR_RS15350	COG0840	transmembrane signaling receptor activity
UGYR_RS15360	COG0596	Alpha beta hydrolase
UGYR_RS15365	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
UGYR_RS15370	COG0033	Phosphoglucomutase
UGYR_RS15380	COG0745	RESPONSE REGULATOR receiver
UGYR_RS15385	COG2205	protein histidine kinase activity
UGYR_RS15390	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
UGYR_RS15395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
UGYR_RS15415	COG3272	Protein of unknown function (DUF1722)
UGYR_RS15420	COG0415	Belongs to the DNA photolyase family
UGYR_RS15425	COG5212	phosphodiesterase
UGYR_RS15430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
UGYR_RS15435	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
UGYR_RS15440	COG1984	allophanate hydrolase subunit 2
UGYR_RS15445	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
UGYR_RS15480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
UGYR_RS15485	COG1053	succinate dehydrogenase
UGYR_RS15490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UGYR_RS15495	COG0567	Dehydrogenase, E1 component
UGYR_RS15500	COG0508	dehydrogenase complex catalyzes the overall conversion of
UGYR_RS15505	COG0045	succinate-CoA ligase (ADP-forming) activity
UGYR_RS15510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
UGYR_RS15515	COG0737	Belongs to the 5'-nucleotidase family
UGYR_RS15520	COG1271	oxidase subunit
UGYR_RS15525	COG1294	oxidase, subunit
UGYR_RS15530	COG4890	Cyd operon protein YbgT
UGYR_RS15535	COG3790	cyd operon protein YbgE
UGYR_RS15540	COG0824	Thioesterase
UGYR_RS15545	COG0811	peptide transport
UGYR_RS15550	COG0848	biopolymer transport protein
UGYR_RS15555	COG3064	Membrane
UGYR_RS15555	COG3064	Membrane
UGYR_RS15560	COG0823	Involved in the tonB-independent uptake of proteins
UGYR_RS15565	COG2885	chlorophyll binding
UGYR_RS15570	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
UGYR_RS15595	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
UGYR_RS15605	COG2205	protein histidine kinase activity
UGYR_RS15605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_RS15615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UGYR_RS15620	COG0588	phosphoglycerate mutase activity
UGYR_RS15630	COG2017	converts alpha-aldose to the beta-anomer
UGYR_RS15640	COG1085	galactose-1-phosphate uridylyltransferase
UGYR_RS15645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
UGYR_RS15655	COG2005	Transcriptional regulator
UGYR_RS15655	COG3585	molybdate ion transport
UGYR_RS15665	COG0725	ABC transporter, periplasmic molybdate-binding protein
UGYR_RS15670	COG4149	molybdate abc transporter
UGYR_RS15680	COG0561	phosphatase activity
UGYR_RS15685	COG2706	6-phosphogluconolactonase activity
UGYR_RS15700	COG0156	8-amino-7-oxononanoate synthase activity
UGYR_RS15705	COG2226	methyltransferase
UGYR_RS15720	COG0556	nucleotide-excision repair
UGYR_RS15725	COG4628	conserved protein (DUF2132)
UGYR_RS15740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_RS15745	COG1120	ATPase activity
UGYR_RS15750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
UGYR_RS15755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
UGYR_RS15765	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
UGYR_RS15770	COG0314	molybdopterin synthase activity
UGYR_RS15775	COG0670	Belongs to the BI1 family
UGYR_RS15780	COG0842	Transport permease protein
UGYR_RS15785	COG0842	Transport permease protein
UGYR_RS15790	COG1131	(ABC) transporter
UGYR_RS15795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_RS15800	COG1309	transcriptional regulator
UGYR_RS15805	COG0513	Belongs to the DEAD box helicase family
UGYR_RS15810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UGYR_RS15820	COG1686	Belongs to the peptidase S11 family
UGYR_RS15825	COG0277	FAD linked oxidase domain protein
UGYR_RS15845	COG2261	transglycosylase associated protein
UGYR_RS15855	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
UGYR_RS15865	COG3639	organic phosphonate transmembrane transporter activity
UGYR_RS15870	COG4807	Protein conserved in bacteria
UGYR_RS15875	COG2897	thiosulfate sulfurtransferase activity
UGYR_RS15880	COG1732	Glycine betaine
UGYR_RS15885	COG1174	glycine betaine transport
UGYR_RS15890	COG1125	glycine betaine transport
UGYR_RS15895	COG1174	glycine betaine transport
UGYR_RS15900	COG0531	amino acid
UGYR_RS15905	COG1982	Orn Lys Arg decarboxylase major
UGYR_RS15915	COG0697	spore germination
UGYR_RS15930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
UGYR_RS15935	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
UGYR_RS15940	COG1126	abc transporter atp-binding protein
UGYR_RS15945	COG0765	amino acid transport
UGYR_RS15950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_RS15970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
UGYR_RS15975	COG2239	Acts as a magnesium transporter
UGYR_RS15985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
UGYR_RS15990	COG0488	(ABC) transporter
UGYR_RS15995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UGYR_RS16000	COG0303	'Molybdopterin
UGYR_RS16020	COG0583	DNA-binding transcription factor activity
UGYR_RS16025	COG0477	Major facilitator Superfamily
UGYR_RS16030	COG0302	gtp cyclohydrolase
UGYR_RS16035	COG2311	Membrane
UGYR_RS16060	COG2949	membrane
UGYR_RS16065	COG0281	malic enzyme
UGYR_RS16075	COG0583	DNA-binding transcription factor activity
UGYR_RS16085	COG1346	cytolysis
UGYR_RS16090	COG1380	Effector of murein hydrolase LrgA
UGYR_RS16100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UGYR_RS16100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UGYR_RS16105	COG0489	protein tyrosine kinase activity
UGYR_RS16110	COG0572	uridine kinase
UGYR_RS16115	COG0717	Belongs to the dCTP deaminase family
UGYR_RS16120	COG2982	Protein involved in outer membrane biogenesis
UGYR_RS16125	COG3069	C4-dicarboxylate transmembrane transporter activity
UGYR_RS16130	COG1253	flavin adenine dinucleotide binding
UGYR_RS16135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
UGYR_RS16140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
UGYR_RS16145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
UGYR_RS16150	COG0140	phosphoribosyl-ATP diphosphatase activity
UGYR_RS16150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
UGYR_RS16160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
UGYR_RS16170	COG0131	Imidazoleglycerol-phosphate dehydratase
UGYR_RS16170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UGYR_RS16175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
UGYR_RS16180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
UGYR_RS16190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UGYR_RS16195	COG0625	glutathione transferase activity
UGYR_RS16210	COG0626	cystathionine gamma-synthase activity
UGYR_RS16220	COG1686	Belongs to the peptidase S11 family
UGYR_RS16225	COG1760	l-serine dehydratase
UGYR_RS16230	COG0814	amino acid
UGYR_RS16235	COG1349	DNA-binding transcription factor activity
UGYR_RS16245	COG0671	phosphoesterase, PA-phosphatase related
UGYR_RS16255	COG0569	domain protein
UGYR_RS16255	COG2985	domain, Protein
UGYR_RS16275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
UGYR_RS16280	COG3842	ATPase activity
UGYR_RS16285	COG1176	ABC-type spermidine putrescine transport system, permease component I
UGYR_RS16290	COG1177	transmembrane transport
UGYR_RS16305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_RS16310	COG4160	amino acid transport
UGYR_RS16315	COG4215	(ABC) transporter
UGYR_RS16320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_RS16325	COG1126	abc transporter atp-binding protein
UGYR_RS16335	COG0393	Putative heavy-metal-binding
UGYR_RS16340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UGYR_RS16345	COG0702	epimerase
UGYR_RS16350	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
UGYR_RS16355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UGYR_RS16360	COG1151	hydroxylamine reductase activity
UGYR_RS16365	COG2431	L-lysine efflux transmembrane transporter activity
UGYR_RS16370	COG3593	DNA synthesis involved in DNA repair
UGYR_RS16375	COG2990	Protein conserved in bacteria
UGYR_RS16380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_RS16390	COG1278	Cold shock
UGYR_RS16395	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
UGYR_RS16400	COG0542	response to heat
UGYR_RS16405	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
UGYR_RS16415	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
UGYR_RS16425	COG0492	ferredoxin-NADP+ reductase activity
UGYR_RS16430	COG1522	sequence-specific DNA binding
UGYR_RS16435	COG1674	ftsk spoiiie
UGYR_RS16435	COG3107	peptidoglycan biosynthetic process
UGYR_RS16440	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
UGYR_RS16445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
UGYR_RS16450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
UGYR_RS16455	COG2814	Major facilitator Superfamily
UGYR_RS16460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
UGYR_RS16465	COG1882	Formate acetyltransferase
UGYR_RS16470	COG2116	formate transmembrane transporter activity
UGYR_RS16475	COG1944	ATP diphosphatase activity
UGYR_RS16480	COG0252	asparaginase activity
UGYR_RS16490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
UGYR_RS16500	COG0539	negative regulation of cytoplasmic translation
UGYR_RS16510	COG0658	competence protein
UGYR_RS16510	COG2333	competence protein COMEC
UGYR_RS16520	COG1663	tetraacyldisaccharide 4'-kinase activity
UGYR_RS16525	COG5383	Protein conserved in bacteria
UGYR_RS16535	COG1278	Cold shock
UGYR_RS16540	COG2835	tetraacyldisaccharide 4'-kinase activity
UGYR_RS16545	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
UGYR_RS16550	COG3173	Aminoglycoside phosphotransferase
UGYR_RS16555	COG1434	Gram-negative-bacterium-type cell wall biogenesis
UGYR_RS16560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UGYR_RS16565	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
UGYR_RS16575	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
UGYR_RS16580	COG2989	Protein conserved in bacteria
UGYR_RS16585	COG3108	Peptidase M15
UGYR_RS16590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UGYR_RS16595	COG1448	Aminotransferase
UGYR_RS16625	COG3710	Transcriptional regulator