locus-tag	class	description
CLC90_RS00005	COG0527	aspartate kinase activity
CLC90_RS00005	COG0460	homoserine dehydrogenase
CLC90_RS00010	COG0626	cystathionine gamma-synthase activity
CLC90_RS00015	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CLC90_RS00025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLC90_RS00030	COG1609	Transcriptional regulator
CLC90_RS00035	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLC90_RS00040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CLC90_RS00045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CLC90_RS00050	COG1575	Belongs to the MenA family. Type 1 subfamily
CLC90_RS00055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CLC90_RS00060	COG3074	FtsZ-dependent cytokinesis
CLC90_RS00070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CLC90_RS00075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLC90_RS00080	COG1494	fructose-1,6-bisphosphatase
CLC90_RS00085	COG2814	Major facilitator Superfamily
CLC90_RS00095	COG3152	Membrane
CLC90_RS00110	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CLC90_RS00120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLC90_RS00125	COG3678	ATP-independent chaperone mediated protein folding
CLC90_RS00130	COG0745	RESPONSE REGULATOR receiver
CLC90_RS00135	COG2205	protein histidine kinase activity
CLC90_RS00140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CLC90_RS00145	COG1045	serine acetyltransferase
CLC90_RS00150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CLC90_RS00155	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CLC90_RS00160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLC90_RS00165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLC90_RS00170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CLC90_RS00175	COG4942	peptidase
CLC90_RS00180	COG2861	carbohydrate metabolic process
CLC90_RS00195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLC90_RS00200	COG0859	PFAM glycosyl transferase family 9
CLC90_RS00205	COG0859	PFAM glycosyl transferase family 9
CLC90_RS00210	COG1519	Transferase
CLC90_RS00230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CLC90_RS00235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CLC90_RS00245	COG2003	Belongs to the UPF0758 family
CLC90_RS00250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLC90_RS00255	COG0756	dUTP diphosphatase activity
CLC90_RS00260	COG1309	transcriptional regulator
CLC90_RS00265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLC90_RS00270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLC90_RS00275	COG1561	YicC-like family, N-terminal region
CLC90_RS00290	COG5001	Diguanylate cyclase
CLC90_RS00295	COG1024	Enoyl-CoA hydratase
CLC90_RS00300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLC90_RS00310	COG2860	membrane
CLC90_RS00315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLC90_RS00325	COG1758	RNA polymerase activity
CLC90_RS00330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLC90_RS00335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLC90_RS00340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLC90_RS00345	COG0786	glutamate:sodium symporter activity
CLC90_RS00350	COG2233	PERMEase
CLC90_RS00355	COG2982	Protein involved in outer membrane biogenesis
CLC90_RS00360	COG0456	acetyltransferase
CLC90_RS00375	COG1011	Hydrolase
CLC90_RS00390	COG3852	Histidine kinase
CLC90_RS00400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLC90_RS00415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CLC90_RS00420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLC90_RS00420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLC90_RS00425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLC90_RS00430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLC90_RS00435	COG3084	Protein conserved in bacteria
CLC90_RS00445	COG1763	Mo-molybdopterin cofactor biosynthetic process
CLC90_RS00470	COG2186	Transcriptional regulator
CLC90_RS00475	COG1609	Transcriptional regulator
CLC90_RS00480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLC90_RS00490	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLC90_RS00495	COG1129	ABC transporter
CLC90_RS00500	COG1869	D-ribose catabolic process
CLC90_RS00505	COG3158	transport of potassium into the cell
CLC90_RS00510	COG0714	Associated with various cellular activities
CLC90_RS00515	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CLC90_RS00525	COG2502	aspartate--ammonia ligase
CLC90_RS00530	COG1522	sequence-specific DNA binding
CLC90_RS00535	COG0716	FMN binding
CLC90_RS00545	COG0445	tRNA wobble uridine modification
CLC90_RS00550	COG0357	Ribosomal RNA small subunit methyltransferase G
CLC90_RS00555	COG3312	ion transport
CLC90_RS00560	COG0356	it plays a direct role in the translocation of protons across the membrane
CLC90_RS00570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLC90_RS00580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLC90_RS00585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLC90_RS00595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CLC90_RS00610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CLC90_RS00615	COG0573	inorganic phosphate transmembrane transporter activity
CLC90_RS00620	COG0581	inorganic phosphate transmembrane transporter activity
CLC90_RS00630	COG0704	Plays a role in the regulation of phosphate uptake
CLC90_RS00635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLC90_RS00640	COG0765	amino acid transport
CLC90_RS00645	COG0765	amino acid transport
CLC90_RS00650	COG2252	PERMEase
CLC90_RS00655	COG0840	transmembrane signaling receptor activity
CLC90_RS00665	COG3121	Chaperone
CLC90_RS00680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLC90_RS00685	COG0706	membrane insertase activity
CLC90_RS00695	COG0594	ribonuclease P activity
CLC90_RS00700	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CLC90_RS00715	COG0592	DNA-directed DNA polymerase activity
CLC90_RS00725	COG0187	DNA topoisomerase II activity
CLC90_RS00730	COG0561	phosphatase activity
CLC90_RS00735	COG0823	Involved in the tonB-independent uptake of proteins
CLC90_RS00740	COG5645	(Lipo)protein
CLC90_RS00755	COG0569	domain protein
CLC90_RS00755	COG2985	domain, Protein
CLC90_RS00760	COG3977	Valine--pyruvate aminotransferase
CLC90_RS00765	COG2885	chlorophyll binding
CLC90_RS00785	COG2818	Glycosylase
CLC90_RS00835	COG2213	PTS system mannitol-specific
CLC90_RS00835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLC90_RS00845	COG3722	fumarate hydratase activity
CLC90_RS00855	COG2258	MOSC domain
CLC90_RS00860	COG0840	transmembrane signaling receptor activity
CLC90_RS00865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLC90_RS00875	COG0243	molybdopterin cofactor binding
CLC90_RS00875	COG3383	formate dehydrogenase (NAD+) activity
CLC90_RS00880	COG3383	formate dehydrogenase (NAD+) activity
CLC90_RS00880	COG0243	molybdopterin cofactor binding
CLC90_RS00885	COG0437	4 iron, 4 sulfur cluster binding
CLC90_RS00890	COG2864	formate dehydrogenase
CLC90_RS00900	COG1921	L-seryl-tRNASec selenium transferase activity
CLC90_RS00905	COG3276	selenocysteine insertion sequence binding
CLC90_RS00910	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CLC90_RS00920	COG3274	enterobacterial common antigen metabolic process
CLC90_RS00925	COG0582	viral genome integration into host DNA
CLC90_RS00960	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CLC90_RS00965	COG2986	histidine ammonia-lyase
CLC90_RS00985	COG2194	sulfuric ester hydrolase activity
CLC90_RS00990	COG2197	response regulator
CLC90_RS00995	COG3851	Histidine kinase
CLC90_RS01000	COG2271	Major facilitator Superfamily
CLC90_RS01010	COG0747	negative chemotaxis
CLC90_RS01015	COG0601	transmembrane transport
CLC90_RS01020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLC90_RS01025	COG0444	Belongs to the ABC transporter superfamily
CLC90_RS01030	COG4608	Belongs to the ABC transporter superfamily
CLC90_RS01035	COG2194	sulfuric ester hydrolase activity
CLC90_RS01060	COG1215	transferase activity, transferring glycosyl groups
CLC90_RS01065	COG1215	transferase activity, transferring glycosyl groups
CLC90_RS01070	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CLC90_RS01075	COG0457	Tetratricopeptide repeat
CLC90_RS01075	COG3118	belongs to the thioredoxin family
CLC90_RS01080	COG2200	EAL domain
CLC90_RS01080	COG2199	diguanylate cyclase activity
CLC90_RS01085	COG1301	dicarboxylic acid transport
CLC90_RS01090	COG0612	Peptidase, M16
CLC90_RS01095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLC90_RS01100	COG1942	4-Oxalocrotonate Tautomerase
CLC90_RS01105	COG2200	EAL domain
CLC90_RS01110	COG2134	cdp-diacylglycerol pyrophosphatase
CLC90_RS01115	COG1295	ribonuclease BN
CLC90_RS01125	COG1301	dicarboxylic acid transport
CLC90_RS01130	COG0626	cystathionine gamma-synthase activity
CLC90_RS01145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLC90_RS01150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CLC90_RS01155	COG0339	signal peptide processing
CLC90_RS01160	COG0742	ribosomal rna small subunit methyltransferase
CLC90_RS01170	COG0589	response to stress
CLC90_RS01180	COG0306	phosphate transporter
CLC90_RS01185	COG2081	HI0933 family
CLC90_RS01195	COG1247	-acetyltransferase
CLC90_RS01200	COG1741	Belongs to the pirin family
CLC90_RS01205	COG1609	Transcriptional regulator
CLC90_RS01210	COG2610	gluconate transmembrane transporter activity
CLC90_RS01215	COG3265	gluconokinase activity
CLC90_RS01220	COG2095	MarC family integral membrane protein
CLC90_RS01225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLC90_RS01230	COG3275	phosphorelay sensor kinase activity
CLC90_RS01235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLC90_RS01240	COG1523	belongs to the glycosyl hydrolase 13 family
CLC90_RS01245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLC90_RS01250	COG0297	glycogen (starch) synthase activity
CLC90_RS01255	COG0058	SHG alpha-glucan phosphorylase activity
CLC90_RS01260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLC90_RS01265	COG1349	DNA-binding transcription factor activity
CLC90_RS01270	COG0705	Rhomboid family
CLC90_RS01280	COG2909	trisaccharide binding
CLC90_RS01285	COG0058	SHG alpha-glucan phosphorylase activity
CLC90_RS01290	COG1640	4-alpha-glucanotransferase
CLC90_RS01300	COG1040	competence protein
CLC90_RS01305	COG0596	Alpha beta hydrolase
CLC90_RS01325	COG1918	ferrous iron import across plasma membrane
CLC90_RS01330	COG2183	response to ionizing radiation
CLC90_RS01355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLC90_RS01370	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CLC90_RS01380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CLC90_RS01385	COG1011	Hydrolase
CLC90_RS01395	COG0494	nUDIX hydrolase
CLC90_RS01400	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CLC90_RS01425	COG4796	Type ii and iii secretion system protein
CLC90_RS01430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLC90_RS01450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CLC90_RS01460	COG0180	Tryptophanyl-tRNA synthetase
CLC90_RS01480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLC90_RS01485	COG0402	S-adenosylhomocysteine deaminase activity
CLC90_RS01490	COG0738	Major facilitator superfamily
CLC90_RS01505	COG1609	Transcriptional regulator
CLC90_RS01510	COG1486	melibiose metabolic process
CLC90_RS01515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLC90_RS01530	COG1289	transmembrane transporter activity
CLC90_RS01535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLC90_RS01540	COG1765	OsmC-like protein
CLC90_RS01565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLC90_RS01570	COG3954	Phosphoribulokinase
CLC90_RS01580	COG0429	hydrolase of the alpha beta-hydrolase fold
CLC90_RS01590	COG0859	PFAM glycosyl transferase family 9
CLC90_RS01595	COG1216	Glycosyl transferase, family 2
CLC90_RS01600	COG0488	(ABC) transporter
CLC90_RS01605	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLC90_RS01615	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CLC90_RS01620	COG1047	Peptidyl-prolyl cis-trans
CLC90_RS01630	COG0545	Peptidyl-prolyl cis-trans isomerase
CLC90_RS01635	COG2964	Protein conserved in bacteria
CLC90_RS01645	COG2923	Belongs to the DsrF TusC family
CLC90_RS01650	COG2168	tRNA wobble position uridine thiolation
CLC90_RS01655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLC90_RS01660	COG0049	tRNA binding
CLC90_RS01675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLC90_RS01690	COG0051	transcription antitermination factor activity, RNA binding
CLC90_RS01695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLC90_RS01705	COG0089	rRNA binding
CLC90_RS01710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLC90_RS01715	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLC90_RS01720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLC90_RS01730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLC90_RS01735	COG0255	Belongs to the universal ribosomal protein uL29 family
CLC90_RS01740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLC90_RS01745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLC90_RS01755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLC90_RS01780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLC90_RS01785	COG1841	ribosomal large subunit assembly
CLC90_RS01790	COG0200	Binds to the 23S rRNA
CLC90_RS01795	COG0201	protein transport
CLC90_RS01800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLC90_RS01805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLC90_RS01815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLC90_RS01825	COG0203	ribosomal protein L17
CLC90_RS01830	COG0789	Transcriptional regulator
CLC90_RS01835	COG3036	rescue of stalled ribosome
CLC90_RS01840	COG1970	mechanosensitive ion channel activity
CLC90_RS01850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLC90_RS01850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLC90_RS01855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLC90_RS01860	COG0242	peptide deformylase activity
CLC90_RS01865	COG0758	DNA mediated transformation
CLC90_RS01870	COG2922	Belongs to the Smg family
CLC90_RS01875	COG0551	DNA topoisomerase type I activity
CLC90_RS01880	COG0009	L-threonylcarbamoyladenylate synthase
CLC90_RS01890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLC90_RS01920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLC90_RS01925	COG3162	membrane
CLC90_RS01930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CLC90_RS01935	COG1301	dicarboxylic acid transport
CLC90_RS01945	COG2391	methyltransferase activity
CLC90_RS01950	COG0425	Belongs to the sulfur carrier protein TusA family
CLC90_RS01955	COG1086	Polysaccharide biosynthesis protein
CLC90_RS01960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLC90_RS01965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLC90_RS01970	COG2089	acid synthase
CLC90_RS01990	COG2755	lipolytic protein G-D-S-L family
CLC90_RS01990	COG1083	cytidylyl-transferase
CLC90_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
CLC90_RS02015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CLC90_RS02015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLC90_RS02020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLC90_RS02040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLC90_RS02060	COG1309	transcriptional regulator
CLC90_RS02065	COG4232	protein-disulfide reductase activity
CLC90_RS02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CLC90_RS02105	COG1509	lysine 2,3-aminomutase activity
CLC90_RS02115	COG3397	chitin binding
CLC90_RS02135	COG3188	usher protein
CLC90_RS02155	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CLC90_RS02160	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CLC90_RS02165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLC90_RS02170	COG1053	succinate dehydrogenase
CLC90_RS02175	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CLC90_RS02180	COG1511	domain protein
CLC90_RS02180	COG3264	Mechanosensitive ion channel
CLC90_RS02185	COG0688	phosphatidylethanolamine metabolic process
CLC90_RS02190	COG1162	GTPase activity
CLC90_RS02195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CLC90_RS02215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLC90_RS02220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLC90_RS02220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CLC90_RS02225	COG0802	atpase or kinase
CLC90_RS02230	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLC90_RS02240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLC90_RS02250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLC90_RS02255	COG0330	HflC and HflK could
CLC90_RS02260	COG0330	HflC and HflK could
CLC90_RS02265	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CLC90_RS02270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLC90_RS02275	COG1959	2 iron, 2 sulfur cluster binding
CLC90_RS02280	COG0557	exoribonuclease II activity
CLC90_RS02285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLC90_RS02305	COG3121	Chaperone
CLC90_RS02310	COG3188	usher protein
CLC90_RS02330	COG1073	alpha beta
CLC90_RS02345	COG0360	Binds together with S18 to 16S ribosomal RNA
CLC90_RS02350	COG2965	DNA replication, synthesis of RNA primer
CLC90_RS02355	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLC90_RS02360	COG0359	binds to the 23S rRNA
CLC90_RS02365	COG3061	Opacity-associated protein A
CLC90_RS02370	COG0545	Peptidyl-prolyl cis-trans isomerase
CLC90_RS02380	COG0737	Belongs to the 5'-nucleotidase family
CLC90_RS02385	COG1218	3'(2'),5'-bisphosphate nucleotidase
CLC90_RS02390	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CLC90_RS02400	COG1253	flavin adenine dinucleotide binding
CLC90_RS02405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLC90_RS02410	COG0729	surface antigen
CLC90_RS02415	COG2911	Protein conserved in bacteria
CLC90_RS02420	COG2105	PFAM AIG2 family protein
CLC90_RS02425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CLC90_RS02435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLC90_RS02450	COG3423	Transcriptional regulator
CLC90_RS02465	COG0142	geranyltranstransferase activity
CLC90_RS02480	COG0697	spore germination
CLC90_RS02485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLC90_RS02490	COG0642	Histidine kinase
CLC90_RS02495	COG0745	RESPONSE REGULATOR receiver
CLC90_RS02500	COG2027	D-alanyl-D-alanine carboxypeptidase
CLC90_RS02510	COG1534	Rna-binding protein
CLC90_RS02515	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CLC90_RS02525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLC90_RS02530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLC90_RS02535	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CLC90_RS02555	COG0195	Participates in both transcription termination and antitermination
CLC90_RS02565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLC90_RS02580	COG1185	polyribonucleotide nucleotidyltransferase activity
CLC90_RS02595	COG0513	Belongs to the DEAD box helicase family
CLC90_RS02600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLC90_RS02615	COG0826	peptidase U32
CLC90_RS02620	COG0826	peptidase U32
CLC90_RS02625	COG3154	lipid carrier protein
CLC90_RS02630	COG3153	acetyltransferase
CLC90_RS02635	COG2827	Endonuclease containing a URI domain
CLC90_RS02640	COG0531	amino acid
CLC90_RS02645	COG1982	Orn Lys Arg decarboxylase major
CLC90_RS02655	COG3787	Belongs to the UPF0306 family
CLC90_RS02660	COG0702	epimerase
CLC90_RS02665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CLC90_RS02670	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CLC90_RS02675	COG3454	Phosphonate metabolism
CLC90_RS02680	COG4778	phosphonate C-P lyase system protein PhnL
CLC90_RS02685	COG4107	phosphonate C-P lyase system protein PhnK
CLC90_RS02690	COG3627	carbon phosphorus lyase activity
CLC90_RS02695	COG3626	phosphonate metabolism
CLC90_RS02700	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CLC90_RS02705	COG3624	Phosphonate C-P lyase system protein PhnG
CLC90_RS02725	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CLC90_RS02740	COG2927	DNA polymerase III (CHI subunit)
CLC90_RS02745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLC90_RS02750	COG0795	lipopolysaccharide-transporting ATPase activity
CLC90_RS02755	COG0795	lipopolysaccharide-transporting ATPase activity
CLC90_RS02800	COG3077	Addiction module antitoxin, RelB DinJ family
CLC90_RS02905	COG5492	domain, Protein
CLC90_RS02930	COG1349	DNA-binding transcription factor activity
CLC90_RS02940	COG2222	sugar isomerase
CLC90_RS02945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLC90_RS02950	COG3715	PTS system
CLC90_RS02955	COG3716	PTS system mannose fructose sorbose family IID component
CLC90_RS02965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLC90_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
CLC90_RS02985	COG0641	radical SAM
CLC90_RS02990	COG3119	arylsulfatase activity
CLC90_RS03015	COG0859	PFAM glycosyl transferase family 9
CLC90_RS03030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLC90_RS03035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLC90_RS03045	COG2376	Dihydroxyacetone kinase
CLC90_RS03050	COG1461	Dihydroxyacetone kinase
CLC90_RS03055	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CLC90_RS03055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLC90_RS03055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLC90_RS03095	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CLC90_RS03110	COG2823	Periplasmic or secreted lipoprotein
CLC90_RS03120	COG4667	esterase of the alpha-beta hydrolase superfamily
CLC90_RS03125	COG0084	hydrolase, TatD family'
CLC90_RS03130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLC90_RS03145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLC90_RS03155	COG3726	membrane protein affecting hemolysin expression
CLC90_RS03160	COG0560	Phosphoserine phosphatase
CLC90_RS03175	COG0488	(ABC) transporter
CLC90_RS03200	COG0741	lytic transglycosylase activity
CLC90_RS03205	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CLC90_RS03210	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CLC90_RS03215	COG0406	alpha-ribazole phosphatase activity
CLC90_RS03220	COG3708	Transcriptional regulator
CLC90_RS03220	COG2207	Transcriptional regulator
CLC90_RS03225	COG3045	CreA protein
CLC90_RS03230	COG0745	RESPONSE REGULATOR receiver
CLC90_RS03260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLC90_RS03265	COG0521	Mo-molybdopterin cofactor biosynthetic process
CLC90_RS03270	COG0477	Major facilitator Superfamily
CLC90_RS03280	COG1584	GPR1 FUN34 yaaH family protein
CLC90_RS03285	COG0443	Heat shock 70 kDa protein
CLC90_RS03295	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLC90_RS03300	COG0583	DNA-binding transcription factor activity
CLC90_RS03320	COG0196	riboflavin kinase activity
CLC90_RS03330	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLC90_RS03335	COG1047	Peptidyl-prolyl cis-trans
CLC90_RS03340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLC90_RS03355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CLC90_RS03365	COG2966	Psort location CytoplasmicMembrane, score
CLC90_RS03390	COG2967	ApaG domain
CLC90_RS03395	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CLC90_RS03400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CLC90_RS03410	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CLC90_RS03420	COG0564	pseudouridine synthase activity
CLC90_RS03425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CLC90_RS03430	COG0417	DNA replication proofreading
CLC90_RS03435	COG0586	Pfam SNARE associated Golgi protein
CLC90_RS03445	COG1178	ABC-type Fe3 transport system permease component
CLC90_RS03450	COG4143	(ABC) transporter
CLC90_RS03465	COG2814	Major facilitator Superfamily
CLC90_RS03475	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLC90_RS03480	COG0473	3-isopropylmalate dehydrogenase activity
CLC90_RS03500	COG1022	Amp-dependent synthetase and ligase
CLC90_RS03505	COG0028	Belongs to the TPP enzyme family
CLC90_RS03530	COG0275	rRNA processing
CLC90_RS03535	COG3116	cell division
CLC90_RS03540	COG0768	penicillin binding
CLC90_RS03545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLC90_RS03550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CLC90_RS03565	COG0772	Belongs to the SEDS family
CLC90_RS03570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLC90_RS03575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CLC90_RS03585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CLC90_RS03590	COG0849	cell division
CLC90_RS03595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLC90_RS03620	COG0494	nUDIX hydrolase
CLC90_RS03640	COG0516	GMP reductase activity
CLC90_RS03650	COG1459	type II secretion system
CLC90_RS03655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLC90_RS03660	COG4969	Belongs to the N-Me-Phe pilin family
CLC90_RS03675	COG3725	Membrane protein required for beta-lactamase induction
CLC90_RS03680	COG1113	amino acid transport
CLC90_RS03690	COG2186	Transcriptional regulator
CLC90_RS03695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CLC90_RS03700	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLC90_RS03705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLC90_RS03715	COG1049	propionate catabolic process, 2-methylcitrate cycle
CLC90_RS03720	COG3112	Uncharacterised protein family (UPF0231)
CLC90_RS03735	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CLC90_RS03745	COG2132	Multicopper oxidase
CLC90_RS03755	COG0288	reversible hydration of carbon dioxide
CLC90_RS03760	COG1131	(ABC) transporter
CLC90_RS03765	COG0842	Transport permease protein
CLC90_RS03770	COG0726	polysaccharide deacetylase
CLC90_RS03775	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CLC90_RS03780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLC90_RS03785	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CLC90_RS03790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLC90_RS03795	COG0617	tRNA 3'-terminal CCA addition
CLC90_RS03815	COG1489	DNA binding
CLC90_RS03820	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CLC90_RS03825	COG1643	Atp-dependent helicase
CLC90_RS03830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLC90_RS03835	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CLC90_RS03845	COG0316	Belongs to the HesB IscA family
CLC90_RS03850	COG2860	membrane
CLC90_RS03860	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLC90_RS03865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CLC90_RS03870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLC90_RS03880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLC90_RS03885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLC90_RS03890	COG3956	TIGRFAM MazG family protein
CLC90_RS03895	COG0504	CTP synthase activity
CLC90_RS03905	COG0602	queuosine metabolic process
CLC90_RS03910	COG0720	synthase
CLC90_RS03915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLC90_RS03925	COG0175	sulfate reduction
CLC90_RS03940	COG2234	aminopeptidase activity
CLC90_RS03945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CLC90_RS03945	COG1648	precorrin-2 dehydrogenase activity
CLC90_RS03950	COG0175	sulfate reduction
CLC90_RS03955	COG2895	sulfate adenylyltransferase (ATP) activity
CLC90_RS03960	COG0529	Catalyzes the synthesis of activated sulfate
CLC90_RS03970	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CLC90_RS03980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CLC90_RS03985	COG0585	pseudouridine synthase activity
CLC90_RS03990	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CLC90_RS04000	COG1388	LysM domain
CLC90_RS04000	COG4942	peptidase
CLC90_RS04005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLC90_RS04010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLC90_RS04085	COG2205	protein histidine kinase activity
CLC90_RS04085	COG0784	Response regulator, receiver
CLC90_RS04105	COG0741	lytic transglycosylase activity
CLC90_RS04240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLC90_RS04260	COG3397	chitin binding
CLC90_RS04270	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CLC90_RS04315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLC90_RS04325	COG3031	protein transport across the cell outer membrane
CLC90_RS04350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CLC90_RS04350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CLC90_RS04365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLC90_RS04370	COG2137	regulation of response to DNA damage stimulus
CLC90_RS04375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLC90_RS04380	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLC90_RS04420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLC90_RS04425	COG1238	metal cluster binding
CLC90_RS04430	COG2918	glutathione biosynthetic process
CLC90_RS04435	COG1854	S-ribosylhomocysteine lyase activity
CLC90_RS04440	COG4536	flavin adenine dinucleotide binding
CLC90_RS04445	COG4137	Cytochrome C assembly protein
CLC90_RS04450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLC90_RS04460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLC90_RS04465	COG0336	Belongs to the RNA methyltransferase TrmD family
CLC90_RS04470	COG0335	large ribosomal subunit rRNA binding
CLC90_RS04475	COG3137	Salt-induced outer membrane protein
CLC90_RS04480	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CLC90_RS04485	COG3279	Response regulator of the LytR AlgR family
CLC90_RS04490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLC90_RS04495	COG1605	Chorismate mutase
CLC90_RS04495	COG0287	Prephenate dehydrogenase
CLC90_RS04500	COG0077	Prephenate dehydratase
CLC90_RS04500	COG1605	Chorismate mutase
CLC90_RS04505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLC90_RS04510	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLC90_RS04520	COG0564	pseudouridine synthase activity
CLC90_RS04525	COG1496	oxidoreductase activity
CLC90_RS04530	COG0542	response to heat
CLC90_RS04565	COG3021	interspecies interaction between organisms
CLC90_RS04570	COG0741	lytic transglycosylase activity
CLC90_RS04570	COG1388	LysM domain
CLC90_RS04580	COG2226	methyltransferase
CLC90_RS04590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CLC90_RS04600	COG1960	acyl-CoA dehydrogenase activity
CLC90_RS04605	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLC90_RS04610	COG0121	glutamine amidotransferase
CLC90_RS04615	COG3034	peptidoglycan biosynthetic process
CLC90_RS04625	COG1805	sodium ion transport
CLC90_RS04630	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CLC90_RS04635	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CLC90_RS04640	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CLC90_RS04650	COG1477	protein flavinylation
CLC90_RS04655	COG2991	Protein conserved in bacteria
CLC90_RS04665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLC90_RS04670	COG2195	Cleaves the N-terminal amino acid of tripeptides
CLC90_RS04675	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CLC90_RS04680	COG1073	alpha beta
CLC90_RS04695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLC90_RS04730	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLC90_RS04750	COG4126	flavin adenine dinucleotide binding
CLC90_RS04760	COG2974	May be involved in recombination
CLC90_RS04765	COG1940	carbohydrate kinase activity
CLC90_RS04770	COG0419	ATPase involved in DNA repair
CLC90_RS04775	COG0420	3'-5' exonuclease activity
CLC90_RS04780	COG0745	RESPONSE REGULATOR receiver
CLC90_RS04785	COG5002	protein histidine kinase activity
CLC90_RS04800	COG1113	amino acid transport
CLC90_RS04805	COG0366	Alpha amylase catalytic
CLC90_RS04810	COG0300	oxidoreductase activity
CLC90_RS04815	COG0450	alkyl hydroperoxide reductase
CLC90_RS04820	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CLC90_RS04835	COG1862	Preprotein translocase
CLC90_RS04840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLC90_RS04845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLC90_RS04850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLC90_RS04855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLC90_RS04855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLC90_RS04860	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CLC90_RS04870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLC90_RS04875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CLC90_RS04880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLC90_RS04885	COG0142	geranyltranstransferase activity
CLC90_RS04920	COG0693	protein deglycase activity
CLC90_RS04925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLC90_RS04930	COG1666	GTP binding
CLC90_RS04935	COG2814	Major facilitator Superfamily
CLC90_RS04945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CLC90_RS04950	COG1845	cytochrome c oxidase, subunit III
CLC90_RS04955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLC90_RS04960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CLC90_RS04970	COG2223	nitrite transmembrane transporter activity
CLC90_RS04975	COG3056	Lipoprotein
CLC90_RS04980	COG0271	Belongs to the BolA IbaG family
CLC90_RS04995	COG0740	serine-type endopeptidase activity
CLC90_RS05000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLC90_RS05005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLC90_RS05010	COG0776	regulation of translation
CLC90_RS05015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLC90_RS05020	COG1555	photosystem II stabilization
CLC90_RS05025	COG0824	Thioesterase
CLC90_RS05030	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLC90_RS05035	COG4533	DNA binding
CLC90_RS05050	COG1522	sequence-specific DNA binding
CLC90_RS05055	COG1132	(ABC) transporter
CLC90_RS05060	COG1132	(ABC) transporter
CLC90_RS05065	COG0347	Belongs to the P(II) protein family
CLC90_RS05070	COG0004	ammonium transporteR
CLC90_RS05075	COG1946	Acyl-CoA thioesterase
CLC90_RS05080	COG3695	enzyme binding
CLC90_RS05105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CLC90_RS05110	COG0254	rRNA binding
CLC90_RS05115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLC90_RS05120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLC90_RS05125	COG1309	transcriptional regulator
CLC90_RS05130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CLC90_RS05135	COG1196	nuclear chromosome segregation
CLC90_RS05135	COG3264	Mechanosensitive ion channel
CLC90_RS05150	COG2832	Protein of unknown function (DUF454)
CLC90_RS05155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLC90_RS05195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLC90_RS05200	COG0326	Molecular chaperone. Has ATPase activity
CLC90_RS05215	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CLC90_RS05220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLC90_RS05225	COG4651	solute:proton antiporter activity
CLC90_RS05225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLC90_RS05230	COG0737	Belongs to the 5'-nucleotidase family
CLC90_RS05235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLC90_RS05240	COG3735	TraB family
CLC90_RS05245	COG2217	Heavy metal translocating P-type atpase
CLC90_RS05250	COG0789	Transcriptional regulator
CLC90_RS05255	COG1585	Membrane protein implicated in regulation of membrane protease activity
CLC90_RS05260	COG0330	HflC and HflK could
CLC90_RS05265	COG3118	belongs to the thioredoxin family
CLC90_RS05270	COG0300	oxidoreductase activity
CLC90_RS05275	COG2755	lipolytic protein G-D-S-L family
CLC90_RS05280	COG4181	ATPase activity
CLC90_RS05285	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CLC90_RS05290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLC90_RS05295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLC90_RS05300	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLC90_RS05305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLC90_RS05330	COG3188	usher protein
CLC90_RS05335	COG3121	Chaperone
CLC90_RS05365	COG2501	S4 domain
CLC90_RS05370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLC90_RS05385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLC90_RS05390	COG1393	Belongs to the ArsC family
CLC90_RS05400	COG1022	Amp-dependent synthetase and ligase
CLC90_RS05425	COG3038	cytochrome b561
CLC90_RS05455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CLC90_RS05465	COG1215	transferase activity, transferring glycosyl groups
CLC90_RS05485	COG3250	beta-galactosidase activity
CLC90_RS05500	COG1309	transcriptional regulator
CLC90_RS05530	COG2197	response regulator
CLC90_RS05535	COG1278	Cold shock
CLC90_RS05555	COG3706	GGDEF domain
CLC90_RS05565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CLC90_RS05575	COG2921	Belongs to the UPF0250 family
CLC90_RS05580	COG1686	Belongs to the peptidase S11 family
CLC90_RS05585	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CLC90_RS05590	COG0772	Belongs to the SEDS family
CLC90_RS05595	COG0768	penicillin binding
CLC90_RS05600	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLC90_RS05605	COG0799	negative regulation of ribosome biogenesis
CLC90_RS05610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLC90_RS05615	COG1466	dna polymerase III delta subunit
CLC90_RS05620	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CLC90_RS05630	COG2888	peptidyl-tyrosine sulfation
CLC90_RS05635	COG1126	abc transporter atp-binding protein
CLC90_RS05640	COG0765	amino acid transport
CLC90_RS05645	COG0765	amino acid transport
CLC90_RS05655	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CLC90_RS05660	COG4535	Mg2 and Co2 transporter CorC
CLC90_RS05665	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLC90_RS05670	COG1702	phosphate starvation-inducible protein PhoH
CLC90_RS05675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLC90_RS05680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLC90_RS05715	COG0367	asparagine synthase
CLC90_RS05720	COG0647	UMP catabolic process
CLC90_RS05725	COG1940	carbohydrate kinase activity
CLC90_RS05725	COG1846	Transcriptional regulator
CLC90_RS05730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLC90_RS05740	COG2190	(PTS) system
CLC90_RS05740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLC90_RS05740	COG1263	PTS System
CLC90_RS05765	COG0735	belongs to the Fur family
CLC90_RS05775	COG0840	transmembrane signaling receptor activity
CLC90_RS05785	COG0596	Alpha beta hydrolase
CLC90_RS05790	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CLC90_RS05795	COG0033	Phosphoglucomutase
CLC90_RS05805	COG0745	RESPONSE REGULATOR receiver
CLC90_RS05810	COG2205	protein histidine kinase activity
CLC90_RS05815	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CLC90_RS05820	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CLC90_RS05840	COG3272	Protein of unknown function (DUF1722)
CLC90_RS05845	COG0415	Belongs to the DNA photolyase family
CLC90_RS05850	COG5212	phosphodiesterase
CLC90_RS05855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLC90_RS05860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CLC90_RS05865	COG1984	allophanate hydrolase subunit 2
CLC90_RS05870	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CLC90_RS05905	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CLC90_RS05910	COG1053	succinate dehydrogenase
CLC90_RS05915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CLC90_RS05920	COG0567	Dehydrogenase, E1 component
CLC90_RS05925	COG0508	dehydrogenase complex catalyzes the overall conversion of
CLC90_RS05930	COG0045	succinate-CoA ligase (ADP-forming) activity
CLC90_RS05935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CLC90_RS05940	COG0737	Belongs to the 5'-nucleotidase family
CLC90_RS05945	COG1271	oxidase subunit
CLC90_RS05950	COG1294	oxidase, subunit
CLC90_RS05955	COG4890	Cyd operon protein YbgT
CLC90_RS05960	COG3790	cyd operon protein YbgE
CLC90_RS05965	COG0824	Thioesterase
CLC90_RS05970	COG0811	peptide transport
CLC90_RS05975	COG0848	biopolymer transport protein
CLC90_RS05980	COG3064	Membrane
CLC90_RS05980	COG3064	Membrane
CLC90_RS05985	COG0823	Involved in the tonB-independent uptake of proteins
CLC90_RS05990	COG2885	chlorophyll binding
CLC90_RS05995	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CLC90_RS06035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CLC90_RS06045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLC90_RS06045	COG2205	protein histidine kinase activity
CLC90_RS06055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLC90_RS06060	COG0588	phosphoglycerate mutase activity
CLC90_RS06070	COG2017	converts alpha-aldose to the beta-anomer
CLC90_RS06080	COG1085	galactose-1-phosphate uridylyltransferase
CLC90_RS06085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CLC90_RS06095	COG2005	Transcriptional regulator
CLC90_RS06095	COG3585	molybdate ion transport
CLC90_RS06105	COG0725	ABC transporter, periplasmic molybdate-binding protein
CLC90_RS06110	COG4149	molybdate abc transporter
CLC90_RS06120	COG0561	phosphatase activity
CLC90_RS06125	COG2706	6-phosphogluconolactonase activity
CLC90_RS06140	COG0156	8-amino-7-oxononanoate synthase activity
CLC90_RS06145	COG2226	methyltransferase
CLC90_RS06160	COG0556	nucleotide-excision repair
CLC90_RS06165	COG4628	conserved protein (DUF2132)
CLC90_RS06180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLC90_RS06185	COG1120	ATPase activity
CLC90_RS06190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CLC90_RS06205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CLC90_RS06210	COG0314	molybdopterin synthase activity
CLC90_RS06215	COG0670	Belongs to the BI1 family
CLC90_RS06220	COG0842	Transport permease protein
CLC90_RS06225	COG0842	Transport permease protein
CLC90_RS06230	COG1131	(ABC) transporter
CLC90_RS06235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLC90_RS06240	COG1309	transcriptional regulator
CLC90_RS06245	COG0513	Belongs to the DEAD box helicase family
CLC90_RS06250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLC90_RS06260	COG1686	Belongs to the peptidase S11 family
CLC90_RS06265	COG0277	FAD linked oxidase domain protein
CLC90_RS06285	COG2261	transglycosylase associated protein
CLC90_RS06295	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CLC90_RS06305	COG3639	organic phosphonate transmembrane transporter activity
CLC90_RS06310	COG4807	Protein conserved in bacteria
CLC90_RS06315	COG2897	thiosulfate sulfurtransferase activity
CLC90_RS06320	COG1732	Glycine betaine
CLC90_RS06325	COG1174	glycine betaine transport
CLC90_RS06330	COG1125	glycine betaine transport
CLC90_RS06335	COG1174	glycine betaine transport
CLC90_RS06340	COG0531	amino acid
CLC90_RS06345	COG1982	Orn Lys Arg decarboxylase major
CLC90_RS06355	COG0697	spore germination
CLC90_RS06370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLC90_RS06375	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CLC90_RS06380	COG1126	abc transporter atp-binding protein
CLC90_RS06385	COG0765	amino acid transport
CLC90_RS06390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLC90_RS06410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CLC90_RS06415	COG2239	Acts as a magnesium transporter
CLC90_RS06420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLC90_RS06425	COG0488	(ABC) transporter
CLC90_RS06430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLC90_RS06435	COG0303	'Molybdopterin
CLC90_RS06455	COG0583	DNA-binding transcription factor activity
CLC90_RS06460	COG0477	Major facilitator Superfamily
CLC90_RS06465	COG0302	gtp cyclohydrolase
CLC90_RS06470	COG2311	Membrane
CLC90_RS06495	COG2949	membrane
CLC90_RS06500	COG0281	malic enzyme
CLC90_RS06510	COG0583	DNA-binding transcription factor activity
CLC90_RS06520	COG1346	cytolysis
CLC90_RS06525	COG1380	Effector of murein hydrolase LrgA
CLC90_RS06535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLC90_RS06535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLC90_RS06540	COG0489	protein tyrosine kinase activity
CLC90_RS06545	COG0572	uridine kinase
CLC90_RS06550	COG0717	Belongs to the dCTP deaminase family
CLC90_RS06555	COG2982	Protein involved in outer membrane biogenesis
CLC90_RS06560	COG3069	C4-dicarboxylate transmembrane transporter activity
CLC90_RS06565	COG1253	flavin adenine dinucleotide binding
CLC90_RS06570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLC90_RS06575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CLC90_RS06580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CLC90_RS06590	COG0140	phosphoribosyl-ATP diphosphatase activity
CLC90_RS06590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CLC90_RS06600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLC90_RS06610	COG0131	Imidazoleglycerol-phosphate dehydratase
CLC90_RS06610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLC90_RS06615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLC90_RS06620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLC90_RS06635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLC90_RS06640	COG0625	glutathione transferase activity
CLC90_RS06655	COG0626	cystathionine gamma-synthase activity
CLC90_RS06665	COG1686	Belongs to the peptidase S11 family
CLC90_RS06670	COG1760	l-serine dehydratase
CLC90_RS06675	COG0814	amino acid
CLC90_RS06680	COG1349	DNA-binding transcription factor activity
CLC90_RS06690	COG0671	phosphoesterase, PA-phosphatase related
CLC90_RS06700	COG0569	domain protein
CLC90_RS06700	COG2985	domain, Protein
CLC90_RS06720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CLC90_RS06725	COG3842	ATPase activity
CLC90_RS06730	COG1176	ABC-type spermidine putrescine transport system, permease component I
CLC90_RS06735	COG1177	transmembrane transport
CLC90_RS06750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLC90_RS06755	COG4160	amino acid transport
CLC90_RS06760	COG4215	(ABC) transporter
CLC90_RS06765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLC90_RS06770	COG1126	abc transporter atp-binding protein
CLC90_RS06780	COG0393	Putative heavy-metal-binding
CLC90_RS06785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CLC90_RS06790	COG0702	epimerase
CLC90_RS06795	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CLC90_RS06800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLC90_RS06805	COG1151	hydroxylamine reductase activity
CLC90_RS06810	COG2431	L-lysine efflux transmembrane transporter activity
CLC90_RS06815	COG3593	DNA synthesis involved in DNA repair
CLC90_RS06820	COG2990	Protein conserved in bacteria
CLC90_RS06825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLC90_RS06835	COG1278	Cold shock
CLC90_RS06840	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CLC90_RS06845	COG0542	response to heat
CLC90_RS06850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLC90_RS06860	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CLC90_RS06870	COG0492	ferredoxin-NADP+ reductase activity
CLC90_RS06875	COG1522	sequence-specific DNA binding
CLC90_RS06880	COG3107	peptidoglycan biosynthetic process
CLC90_RS06880	COG1674	ftsk spoiiie
CLC90_RS06885	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CLC90_RS06890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CLC90_RS06895	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLC90_RS06900	COG2814	Major facilitator Superfamily
CLC90_RS06905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CLC90_RS06910	COG1882	Formate acetyltransferase
CLC90_RS06915	COG2116	formate transmembrane transporter activity
CLC90_RS06920	COG1944	ATP diphosphatase activity
CLC90_RS06925	COG0252	asparaginase activity
CLC90_RS06935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CLC90_RS06945	COG0539	negative regulation of cytoplasmic translation
CLC90_RS06955	COG0658	competence protein
CLC90_RS06955	COG2333	competence protein COMEC
CLC90_RS06965	COG1663	tetraacyldisaccharide 4'-kinase activity
CLC90_RS06970	COG5383	Protein conserved in bacteria
CLC90_RS06980	COG1278	Cold shock
CLC90_RS06985	COG2835	tetraacyldisaccharide 4'-kinase activity
CLC90_RS06990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CLC90_RS06995	COG3173	Aminoglycoside phosphotransferase
CLC90_RS07000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CLC90_RS07005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLC90_RS07010	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CLC90_RS07020	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CLC90_RS07025	COG2989	Protein conserved in bacteria
CLC90_RS07030	COG3108	Peptidase M15
CLC90_RS07035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CLC90_RS07040	COG1448	Aminotransferase
CLC90_RS07055	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLC90_RS07060	COG0308	aminopeptidase N
CLC90_RS07065	COG0167	dihydroorotate dehydrogenase activity
CLC90_RS07075	COG3217	Mosc domain protein beta barrel domain protein
CLC90_RS07075	COG0633	Ferredoxin
CLC90_RS07080	COG0116	Belongs to the methyltransferase superfamily
CLC90_RS07080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLC90_RS07085	COG0488	(ABC) transporter
CLC90_RS07090	COG2995	paraquat-inducible protein a
CLC90_RS07095	COG3008	intermembrane lipid transfer
CLC90_RS07095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLC90_RS07100	COG3009	Protein conserved in bacteria
CLC90_RS07105	COG3130	regulation of translation
CLC90_RS07110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CLC90_RS07115	COG1067	ATP-dependent peptidase activity
CLC90_RS07120	COG3120	sequence-specific DNA binding
CLC90_RS07130	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
CLC90_RS07135	COG3070	regulator of competence-specific genes
CLC90_RS07140	COG1289	transmembrane transporter activity
CLC90_RS07145	COG3304	Inner membrane component domain
CLC90_RS07150	COG0210	DNA helicase
CLC90_RS07155	COG1803	Methylglyoxal synthase
CLC90_RS07165	COG1832	CoA-binding protein
CLC90_RS07170	COG3785	DNA binding
CLC90_RS07175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CLC90_RS07180	COG1254	Belongs to the acylphosphatase family
CLC90_RS07185	COG2920	part of a sulfur-relay system
CLC90_RS07195	COG0288	reversible hydration of carbon dioxide
CLC90_RS07215	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CLC90_RS07220	COG2943	transferase activity, transferring hexosyl groups
CLC90_RS07235	COG0675	Transposase, IS605 OrfB family
CLC90_RS07250	COG1560	Kdo2-lipid A biosynthetic process
CLC90_RS07260	COG0628	permease
CLC90_RS07270	COG2197	response regulator
CLC90_RS07290	COG0418	dihydroorotase activity
CLC90_RS07295	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CLC90_RS07305	COG1530	ribonuclease E activity
CLC90_RS07315	COG0564	pseudouridine synthase activity
CLC90_RS07320	COG0424	maF-like protein
CLC90_RS07325	COG1399	metal-binding, possibly nucleic acid-binding protein
CLC90_RS07330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CLC90_RS07340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLC90_RS07345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CLC90_RS07355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLC90_RS07360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLC90_RS07365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CLC90_RS07370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLC90_RS07375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLC90_RS07380	COG0470	DNA polymerase III
CLC90_RS07385	COG0084	hydrolase, TatD family'
CLC90_RS07390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLC90_RS07390	COG1263	PTS System
CLC90_RS07395	COG0537	adenosine 5'-monophosphoramidase activity
CLC90_RS07400	COG5633	Lipoprotein
CLC90_RS07405	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CLC90_RS07420	COG3150	esterase
CLC90_RS07425	COG1252	NADH dehydrogenase
CLC90_RS07430	COG3134	Outer membrane lipoprotein
CLC90_RS07435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLC90_RS07445	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLC90_RS07455	COG4591	ABC-type transport system involved in lipoprotein release permease component
CLC90_RS07475	COG2850	peptidyl-arginine hydroxylation
CLC90_RS07480	COG2205	protein histidine kinase activity
CLC90_RS07485	COG0745	RESPONSE REGULATOR receiver
CLC90_RS07495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLC90_RS07500	COG2915	High frequency lysogenization protein hflD homolog
CLC90_RS07505	COG0482	sulfurtransferase activity
CLC90_RS07515	COG1187	pseudouridine synthase activity
CLC90_RS07520	COG0538	isocitrate dehydrogenase activity
CLC90_RS07525	COG2771	luxR family
CLC90_RS07530	COG3916	Acyl-homoserine-lactone synthase
CLC90_RS07535	COG2723	6-phospho-beta-galactosidase activity
CLC90_RS07540	COG0339	signal peptide processing
CLC90_RS07545	COG0840	transmembrane signaling receptor activity
CLC90_RS07570	COG0675	Transposase, IS605 OrfB family
CLC90_RS07580	COG4565	transcriptional regulatory protein
CLC90_RS07585	COG3290	protein histidine kinase activity
CLC90_RS07590	COG0471	metal ion transport
CLC90_RS07630	COG4977	sequence-specific DNA binding
CLC90_RS07635	COG1702	phosphate starvation-inducible protein PhoH
CLC90_RS07640	COG0387	Pfam Sodium calcium exchanger
CLC90_RS07645	COG2375	cellular response to nickel ion
CLC90_RS07650	COG3850	Histidine kinase
CLC90_RS07660	COG1294	oxidase, subunit
CLC90_RS07665	COG1271	oxidase subunit
CLC90_RS07670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLC90_RS07675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CLC90_RS07680	COG3138	arginine N-succinyltransferase
CLC90_RS07690	COG3724	N-succinylarginine dihydrolase activity
CLC90_RS07710	COG1228	amidohydrolase
CLC90_RS07720	COG0402	S-adenosylhomocysteine deaminase activity
CLC90_RS07740	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CLC90_RS07745	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CLC90_RS07750	COG3383	formate dehydrogenase (NAD+) activity
CLC90_RS07755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLC90_RS07760	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CLC90_RS07770	COG3260	NADH ubiquinone oxidoreductase 20
CLC90_RS07775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLC90_RS07780	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CLC90_RS07780	COG3261	NADH dehydrogenase
CLC90_RS07785	COG0650	Formate hydrogenlyase subunit 4
CLC90_RS07790	COG0651	ATP synthesis coupled electron transport
CLC90_RS07795	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLC90_RS07805	COG0375	protein maturation
CLC90_RS07810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CLC90_RS07815	COG0298	carbon dioxide binding
CLC90_RS07820	COG0409	Hydrogenase expression formation protein
CLC90_RS07825	COG0309	Hydrogenase expression formation protein (HypE)
CLC90_RS07860	COG2207	Transcriptional regulator
CLC90_RS07860	COG3708	Transcriptional regulator
CLC90_RS07865	COG0012	GTP binding
CLC90_RS07875	COG0193	aminoacyl-tRNA hydrolase activity
CLC90_RS07885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLC90_RS07895	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CLC90_RS07900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLC90_RS07905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLC90_RS07910	COG2890	protein-(glutamine-N5) methyltransferase activity
CLC90_RS07925	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CLC90_RS07930	COG0659	secondary active sulfate transmembrane transporter activity
CLC90_RS07935	COG3706	GGDEF domain
CLC90_RS07960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLC90_RS07970	COG3381	protein complex oligomerization
CLC90_RS07990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLC90_RS08000	COG0673	inositol 2-dehydrogenase activity
CLC90_RS08005	COG0728	peptidoglycan biosynthetic process
CLC90_RS08030	COG3102	Protein conserved in bacteria
CLC90_RS08035	COG3142	Participates in the control of copper homeostasis
CLC90_RS08050	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CLC90_RS08055	COG1801	Protein of unknown function DUF72
CLC90_RS08065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLC90_RS08070	COG0494	nUDIX hydrolase
CLC90_RS08080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CLC90_RS08090	COG2255	four-way junction helicase activity
CLC90_RS08095	COG3104	oligopeptide transport
CLC90_RS08100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLC90_RS08105	COG1121	(ABC) transporter
CLC90_RS08110	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CLC90_RS08115	COG0739	heme binding
CLC90_RS08120	COG1560	Kdo2-lipid A biosynthetic process
CLC90_RS08125	COG0469	pyruvate kinase activity
CLC90_RS08130	COG1737	Transcriptional regulator
CLC90_RS08135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLC90_RS08140	COG0800	Aldolase
CLC90_RS08150	COG2076	Multidrug Resistance protein
CLC90_RS08155	COG0251	oxidation-reduction process
CLC90_RS08160	COG1199	ATP-dependent helicase activity
CLC90_RS08165	COG1214	PFAM Peptidase M22, glycoprotease
CLC90_RS08170	COG3065	identical protein binding
CLC90_RS08175	COG0318	PFAM AMP-dependent synthetase and ligase
CLC90_RS08180	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CLC90_RS08185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CLC90_RS08190	COG2894	cell division
CLC90_RS08195	COG0850	regulation of cytokinetic process
CLC90_RS08200	COG3100	YcgL domain-containing protein
CLC90_RS08205	COG0179	Fumarylacetoacetate (FAA) hydrolase
CLC90_RS08210	COG2983	Belongs to the UPF0260 family
CLC90_RS08230	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CLC90_RS08240	COG2719	SpoVR family
CLC90_RS08245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CLC90_RS08250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLC90_RS08255	COG2814	Major facilitator Superfamily
CLC90_RS08265	COG2202	Pas domain
CLC90_RS08265	COG2199	diguanylate cyclase activity
CLC90_RS08265	COG2200	EAL domain
CLC90_RS08285	COG2718	Belongs to the UPF0229 family
CLC90_RS08290	COG2766	serine protein kinase
CLC90_RS08300	COG3713	MltA-interacting MipA family protein
CLC90_RS08305	COG2194	sulfuric ester hydrolase activity
CLC90_RS08320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLC90_RS08325	COG3139	Protein of unknown function (DUF1315)
CLC90_RS08330	COG1335	isochorismatase
CLC90_RS08335	COG0252	asparaginase activity
CLC90_RS08340	COG0616	signal peptide processing
CLC90_RS08345	COG0778	Nitroreductase
CLC90_RS08355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLC90_RS08365	COG0494	nUDIX hydrolase
CLC90_RS08370	COG0708	Exodeoxyribonuclease III
CLC90_RS08400	COG0788	formyltetrahydrofolate deformylase activity
CLC90_RS08410	COG1752	Esterase of the alpha-beta hydrolase superfamily
CLC90_RS08415	COG0745	RESPONSE REGULATOR receiver
CLC90_RS08435	COG1454	alcohol dehydrogenase
CLC90_RS08435	COG1012	belongs to the aldehyde dehydrogenase family
CLC90_RS08450	COG2095	MarC family integral membrane protein
CLC90_RS08455	COG4166	transmembrane transport
CLC90_RS08470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLC90_RS08485	COG3099	Belongs to the UPF0263 family
CLC90_RS08490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLC90_RS08510	COG2350	Protein conserved in bacteria
CLC90_RS08525	COG3710	Transcriptional regulator
CLC90_RS08560	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CLC90_RS08585	COG0727	PFAM Uncharacterised protein family (UPF0153)
CLC90_RS08590	COG3047	cAMP biosynthetic process
CLC90_RS08605	COG0133	tryptophan synthase activity
CLC90_RS08610	COG0134	indole-3-glycerol-phosphate synthase activity
CLC90_RS08610	COG0135	phosphoribosylanthranilate isomerase activity
CLC90_RS08620	COG0512	Glutamine amidotransferase of anthranilate synthase
CLC90_RS08630	COG0613	PHP domain protein
CLC90_RS08635	COG0009	L-threonylcarbamoyladenylate synthase
CLC90_RS08655	COG1187	pseudouridine synthase activity
CLC90_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
CLC90_RS08670	COG0616	signal peptide processing
CLC90_RS08690	COG0583	DNA-binding transcription factor activity
CLC90_RS08710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLC90_RS08720	COG0671	phosphoesterase, PA-phosphatase related
CLC90_RS08725	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CLC90_RS08730	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CLC90_RS08750	COG0023	Translation Initiation Factor
CLC90_RS08760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLC90_RS08765	COG5002	protein histidine kinase activity
CLC90_RS08765	COG5001	Diguanylate cyclase
CLC90_RS08765	COG3447	MASE1 domain protein
CLC90_RS08770	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CLC90_RS08775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLC90_RS08785	COG4659	FMN binding
CLC90_RS08795	COG2207	Transcriptional regulator
CLC90_RS08795	COG3708	Transcriptional regulator
CLC90_RS08810	COG4657	Part of a membrane complex involved in electron transport
CLC90_RS08820	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CLC90_RS08830	COG0673	inositol 2-dehydrogenase activity
CLC90_RS08835	COG0385	Bile acid
CLC90_RS08840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CLC90_RS08845	COG5339	Protein conserved in bacteria
CLC90_RS08850	COG1482	cell wall glycoprotein biosynthetic process
CLC90_RS08855	COG0114	fumarate hydratase activity
CLC90_RS08865	COG1940	carbohydrate kinase activity
CLC90_RS08870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLC90_RS08890	COG1742	UPF0060 membrane protein
CLC90_RS08895	COG4221	oxidoreductase activity
CLC90_RS08900	COG3023	N-Acetylmuramoyl-L-alanine amidase
CLC90_RS08920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLC90_RS08960	COG1011	Hydrolase
CLC90_RS08970	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CLC90_RS08975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLC90_RS08980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CLC90_RS08985	COG0589	response to stress
CLC90_RS09015	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CLC90_RS09020	COG3623	hexulose-6-phosphate isomerase
CLC90_RS09025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CLC90_RS09030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CLC90_RS09040	COG0531	amino acid
CLC90_RS09050	COG0745	RESPONSE REGULATOR receiver
CLC90_RS09055	COG2205	protein histidine kinase activity
CLC90_RS09070	COG2207	Transcriptional regulator
CLC90_RS09075	COG1881	PFAM PEBP family protein
CLC90_RS09085	COG3591	Belongs to the peptidase S1B family
CLC90_RS09090	COG1643	Atp-dependent helicase
CLC90_RS09095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLC90_RS09100	COG3784	Protein of unknown function (DUF1318)
CLC90_RS09115	COG2911	Protein conserved in bacteria
CLC90_RS09120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLC90_RS09125	COG3187	Heat shock protein
CLC90_RS09130	COG3042	response to heat
CLC90_RS09135	COG1285	pathogenesis
CLC90_RS09145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLC90_RS09145	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CLC90_RS09145	COG1013	pyruvate-flavodoxin oxidoreductase activity
CLC90_RS09145	COG0674	pyruvate-flavodoxin oxidoreductase activity
CLC90_RS09160	COG4166	transmembrane transport
CLC90_RS09165	COG2866	Carboxypeptidase
CLC90_RS09170	COG4948	Mandelate Racemase Muconate Lactonizing
CLC90_RS09175	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLC90_RS09185	COG5642	Protein of unknown function (DUF2384)
CLC90_RS09190	COG5654	RES domain protein
CLC90_RS09195	COG3768	UPF0283 membrane protein
CLC90_RS09200	COG3106	COG3106 Predicted ATPase
CLC90_RS09210	COG1983	PspC domain protein
CLC90_RS09220	COG1842	Phage shock protein A
CLC90_RS09225	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CLC90_RS09240	COG4166	transmembrane transport
CLC90_RS09250	COG4171	peptide transport system, permease
CLC90_RS09255	COG4172	Belongs to the ABC transporter superfamily
CLC90_RS09260	COG4172	Belongs to the ABC transporter superfamily
CLC90_RS09270	COG3104	oligopeptide transport
CLC90_RS09280	COG0484	heat shock protein binding
CLC90_RS09325	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CLC90_RS09330	COG3133	Outer membrane lipoprotein
CLC90_RS09335	COG1846	Transcriptional regulator
CLC90_RS09345	COG4989	oxidoreductase activity
CLC90_RS09350	COG3313	Fe-S protein
CLC90_RS09355	COG2194	sulfuric ester hydrolase activity
CLC90_RS09360	COG1309	transcriptional regulator
CLC90_RS09365	COG1902	pentaerythritol trinitrate reductase activity
CLC90_RS09380	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CLC90_RS09385	COG0791	NLP P60 protein
CLC90_RS09390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLC90_RS09400	COG1609	Transcriptional regulator
CLC90_RS09405	COG0583	DNA-binding transcription factor activity
CLC90_RS09410	COG2814	Major facilitator Superfamily
CLC90_RS09415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CLC90_RS09420	COG0307	riboflavin synthase, alpha
CLC90_RS09455	COG1388	LysM domain
CLC90_RS09455	COG1376	ErfK ybiS ycfS ynhG family protein
CLC90_RS09460	COG2166	iron-sulfur cluster assembly
CLC90_RS09470	COG0719	Fe-S assembly protein
CLC90_RS09475	COG0396	ATPase activity
CLC90_RS09480	COG0719	Fe-S assembly protein
CLC90_RS09485	COG0316	Belongs to the HesB IscA family
CLC90_RS09490	COG2050	protein possibly involved in aromatic compounds catabolism
CLC90_RS09495	COG0247	lactate metabolic process
CLC90_RS09495	COG0277	FAD linked oxidase domain protein
CLC90_RS09500	COG0628	permease
CLC90_RS09510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLC90_RS09510	COG0574	Belongs to the PEP-utilizing enzyme family
CLC90_RS09515	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CLC90_RS09520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CLC90_RS09530	COG4771	TonB-dependent receptor
CLC90_RS09535	COG3720	iron ion transport
CLC90_RS09540	COG4558	Periplasmic binding protein
CLC90_RS09545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLC90_RS09550	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CLC90_RS09560	COG0095	Lipoate-protein ligase
CLC90_RS09565	COG0791	NLP P60 protein
CLC90_RS09570	COG2076	Multidrug Resistance protein
CLC90_RS09575	COG2076	Multidrug Resistance protein
CLC90_RS09580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLC90_RS09595	COG0463	Glycosyl transferase, family 2
CLC90_RS09600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLC90_RS09610	COG4139	cobalamin transport
CLC90_RS09650	COG2184	nucleotidyltransferase activity
CLC90_RS09665	COG2314	TM2 domain
CLC90_RS09670	COG0776	regulation of translation
CLC90_RS09745	COG0803	Belongs to the bacterial solute-binding protein 9 family
CLC90_RS09750	COG1121	(ABC) transporter
CLC90_RS09755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CLC90_RS09765	COG3001	Fructosamine kinase
CLC90_RS09775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CLC90_RS09780	COG1988	membrane-bound metal-dependent
CLC90_RS09785	COG1823	symporter activity
CLC90_RS09790	COG3023	N-Acetylmuramoyl-L-alanine amidase
CLC90_RS09800	COG2814	Major facilitator Superfamily
CLC90_RS09810	COG0501	Belongs to the peptidase M48B family
CLC90_RS09815	COG0793	Belongs to the peptidase S41A family
CLC90_RS09825	COG1956	GAF domain-containing protein
CLC90_RS09830	COG2995	paraquat-inducible protein a
CLC90_RS09835	COG3008	intermembrane lipid transfer
CLC90_RS09840	COG2203	Gaf domain
CLC90_RS09840	COG3706	GGDEF domain
CLC90_RS09840	COG5001	Diguanylate cyclase
CLC90_RS09840	COG4251	negative regulation of phosphorylation
CLC90_RS10025	COG3772	lysozyme
CLC90_RS10075	COG2974	May be involved in recombination
CLC90_RS10185	COG1276	copper resistance
CLC90_RS10190	COG2372	response to copper ion
CLC90_RS10195	COG1528	Iron-storage protein
CLC90_RS10215	COG1770	oligopeptidase
CLC90_RS10225	COG3097	Belongs to the UPF0267 family
CLC90_RS10230	COG3141	response to X-ray
CLC90_RS10235	COG0513	Belongs to the DEAD box helicase family
CLC90_RS10255	COG0494	nUDIX hydrolase
CLC90_RS10260	COG1760	l-serine dehydratase
CLC90_RS10265	COG1253	flavin adenine dinucleotide binding
CLC90_RS10270	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLC90_RS10270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLC90_RS10275	COG3715	PTS system
CLC90_RS10280	COG3716	PTS system mannose fructose sorbose family IID component
CLC90_RS10285	COG4811	Protein of unknown function (DUF986)
CLC90_RS10290	COG1971	Probably functions as a manganese efflux pump
CLC90_RS10310	COG1960	acyl-CoA dehydrogenase activity
CLC90_RS10320	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CLC90_RS10350	COG2226	methyltransferase
CLC90_RS10355	COG0768	penicillin binding
CLC90_RS10360	COG1496	oxidoreductase activity
CLC90_RS10380	COG1113	amino acid transport
CLC90_RS10415	COG2207	Transcriptional regulator
CLC90_RS10425	COG1132	(ABC) transporter
CLC90_RS10435	COG3706	GGDEF domain
CLC90_RS10435	COG5001	Diguanylate cyclase
CLC90_RS10435	COG4251	negative regulation of phosphorylation
CLC90_RS10435	COG2203	Gaf domain
CLC90_RS10455	COG1181	Belongs to the D-alanine--D-alanine ligase family
CLC90_RS10475	COG1278	Cold shock
CLC90_RS10480	COG1278	Cold shock
CLC90_RS10485	COG1278	Cold shock
CLC90_RS10510	COG1917	Cupin 2, conserved barrel domain protein
CLC90_RS10510	COG2169	Transcriptional regulator
CLC90_RS10515	COG1447	Phosphotransferase system cellobiose-specific component IIA
CLC90_RS10520	COG2723	6-phospho-beta-galactosidase activity
CLC90_RS10525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLC90_RS10530	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CLC90_RS10535	COG1187	pseudouridine synthase activity
CLC90_RS10545	COG3122	Protein conserved in bacteria
CLC90_RS10550	COG1757	Na H antiporter
CLC90_RS10565	COG2235	arginine
CLC90_RS10580	COG0076	glutamate decarboxylase activity
CLC90_RS10585	COG0531	amino acid
CLC90_RS10620	COG2153	protein acetylation
CLC90_RS10625	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CLC90_RS10655	COG0840	transmembrane signaling receptor activity
CLC90_RS10660	COG2801	Transposase and inactivated derivatives
CLC90_RS10685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLC90_RS10690	COG0322	excinuclease ABC activity
CLC90_RS10695	COG2197	response regulator
CLC90_RS10710	COG0582	viral genome integration into host DNA
CLC90_RS10720	COG1113	amino acid transport
CLC90_RS10730	COG0531	amino acid
CLC90_RS10735	COG3710	Transcriptional regulator
CLC90_RS10740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLC90_RS10745	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CLC90_RS10745	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CLC90_RS10745	COG0506	proline dehydrogenase activity
CLC90_RS10750	COG1126	abc transporter atp-binding protein
CLC90_RS10755	COG0765	amino acid transport
CLC90_RS10760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CLC90_RS10765	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CLC90_RS10775	COG1191	sigma factor activity
CLC90_RS10815	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CLC90_RS10820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CLC90_RS10830	COG1677	Flagellar hook-basal body complex protein FliE
CLC90_RS10840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLC90_RS10845	COG1317	bacterial-type flagellum organization
CLC90_RS10850	COG1157	protein secretion by the type III secretion system
CLC90_RS10865	COG1580	Controls the rotational direction of flagella during chemotaxis
CLC90_RS10945	COG1558	bacterial-type flagellum-dependent cell motility
CLC90_RS10950	COG1815	bacterial-type flagellum-dependent cell motility
CLC90_RS10960	COG2747	anti-sigma28 factor FlgM
CLC90_RS10965	COG3418	PFAM FlgN family protein
CLC90_RS10975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLC90_RS10980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLC90_RS10985	COG4935	Belongs to the peptidase S8 family
CLC90_RS10985	COG1404	Belongs to the peptidase S8 family
CLC90_RS10990	COG2197	response regulator
CLC90_RS11005	COG3188	usher protein
CLC90_RS11010	COG3121	Chaperone
CLC90_RS11020	COG3539	Fimbrial protein
CLC90_RS11050	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CLC90_RS11055	COG0745	RESPONSE REGULATOR receiver
CLC90_RS11065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CLC90_RS11070	COG0840	transmembrane signaling receptor activity
CLC90_RS11075	COG0840	transmembrane signaling receptor activity
CLC90_RS11080	COG0835	chemotaxis
CLC90_RS11085	COG0643	Histidine kinase
CLC90_RS11085	COG2198	Histidine kinase
CLC90_RS11090	COG1360	Flagellar Motor Protein
CLC90_RS11115	COG0589	response to stress
CLC90_RS11120	COG1285	pathogenesis
CLC90_RS11125	COG0840	transmembrane signaling receptor activity
CLC90_RS11140	COG1609	Transcriptional regulator
CLC90_RS11150	COG0604	alcohol dehydrogenase
CLC90_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
CLC90_RS11150	COG3321	synthase
CLC90_RS11185	COG0582	viral genome integration into host DNA
CLC90_RS11200	COG3423	Transcriptional regulator
CLC90_RS11235	COG3451	type IV secretory pathway VirB4
CLC90_RS11255	COG3736	Type IV secretory pathway, component VirB8
CLC90_RS11270	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CLC90_RS11290	COG4227	nucleotidyltransferase activity
CLC90_RS11345	COG0471	metal ion transport
CLC90_RS11360	COG3051	citrate lyase alpha subunit
CLC90_RS11365	COG2301	Belongs to the HpcH HpaI aldolase family
CLC90_RS11370	COG3052	prosthetic group binding
CLC90_RS11375	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CLC90_RS11380	COG3290	protein histidine kinase activity
CLC90_RS11385	COG4565	transcriptional regulatory protein
CLC90_RS11400	COG2271	Major facilitator Superfamily
CLC90_RS11405	COG1840	ABC-type Fe3 transport system, periplasmic component
CLC90_RS11415	COG3842	ATPase activity
CLC90_RS11435	COG1289	transmembrane transporter activity
CLC90_RS11445	COG2925	Exonuclease
CLC90_RS11450	COG0531	amino acid
CLC90_RS11460	COG4771	TonB-dependent receptor
CLC90_RS11470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLC90_RS11480	COG0833	amino acid
CLC90_RS11485	COG0583	DNA-binding transcription factor activity
CLC90_RS11495	COG2855	membrane
CLC90_RS11500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CLC90_RS11505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLC90_RS11505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CLC90_RS11505	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CLC90_RS11510	COG1105	Belongs to the carbohydrate kinase PfkB family
CLC90_RS11525	COG3005	denitrification pathway
CLC90_RS11530	COG0243	molybdopterin cofactor binding
CLC90_RS11545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLC90_RS11560	COG0246	Mannitol dehydrogenase
CLC90_RS11575	COG0523	cobalamin synthesis protein
CLC90_RS11580	COG0671	phosphoesterase, PA-phosphatase related
CLC90_RS11585	COG0791	NLP P60 protein
CLC90_RS11590	COG2200	EAL domain
CLC90_RS11595	COG4166	transmembrane transport
CLC90_RS11600	COG4174	ABC transporter (Permease)
CLC90_RS11605	COG4239	(ABC) transporter, permease
CLC90_RS11610	COG4172	Belongs to the ABC transporter superfamily
CLC90_RS11620	COG2814	Major facilitator Superfamily
CLC90_RS11625	COG1187	pseudouridine synthase activity
CLC90_RS11630	COG1061	Type III restriction enzyme res subunit
CLC90_RS11645	COG3082	Protein of unknown function (DUF1414)
CLC90_RS11650	COG3083	sulfuric ester hydrolase activity
CLC90_RS11675	COG3778	Protein conserved in bacteria
CLC90_RS11680	COG3299	homolog of phage Mu protein gp47
CLC90_RS11725	COG4386	tail sheath protein
CLC90_RS11770	COG1802	Transcriptional regulator
CLC90_RS11770	COG4626	Terminase
CLC90_RS11795	COG1876	peptidase activity
CLC90_RS11820	COG2815	serine threonine protein kinase
CLC90_RS11820	COG0515	serine threonine protein kinase
CLC90_RS11835	COG1403	HNH endonuclease
CLC90_RS11850	COG4725	Belongs to the MT-A70-like family
CLC90_RS11855	COG1802	Transcriptional regulator
CLC90_RS11855	COG4626	Terminase
CLC90_RS11890	COG5532	Uncharacterized conserved protein (DUF2303)
CLC90_RS11895	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CLC90_RS11940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CLC90_RS11945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLC90_RS11965	COG2223	nitrite transmembrane transporter activity
CLC90_RS11970	COG2198	Histidine kinase
CLC90_RS11970	COG0642	Histidine kinase
CLC90_RS11980	COG0784	Response regulator, receiver
CLC90_RS11980	COG2205	protein histidine kinase activity
CLC90_RS11990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CLC90_RS11995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLC90_RS12005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLC90_RS12015	COG4574	serine-type endopeptidase inhibitor activity
CLC90_RS12025	COG2246	polysaccharide biosynthetic process
CLC90_RS12040	COG0814	amino acid
CLC90_RS12065	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLC90_RS12070	COG0596	Alpha beta hydrolase
CLC90_RS12075	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CLC90_RS12080	COG1169	isochorismate synthase
CLC90_RS12085	COG4575	ribosome binding
CLC90_RS12100	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLC90_RS12105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CLC90_RS12115	COG0839	Belongs to the complex I subunit 6 family
CLC90_RS12120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLC90_RS12125	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CLC90_RS12130	COG1034	ATP synthesis coupled electron transport
CLC90_RS12150	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLC90_RS12155	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CLC90_RS12160	COG0583	DNA-binding transcription factor activity
CLC90_RS12165	COG0436	Aminotransferase
CLC90_RS12170	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CLC90_RS12175	COG0471	metal ion transport
CLC90_RS12175	COG0490	domain, Protein
CLC90_RS12185	COG3013	Belongs to the UPF0304 family
CLC90_RS12190	COG3092	negative regulation of chromosome organization
CLC90_RS12200	COG0280	phosphate acetyltransferase
CLC90_RS12200	COG0857	belongs to the CobB CobQ family
CLC90_RS12205	COG1609	Transcriptional regulator
CLC90_RS12220	COG3037	sugar-specific permease SgaT UlaA
CLC90_RS12225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CLC90_RS12230	COG0622	Phosphoesterase
CLC90_RS12245	COG0625	glutathione transferase activity
CLC90_RS12250	COG1090	epimerase
CLC90_RS12260	COG4160	amino acid transport
CLC90_RS12265	COG4215	(ABC) transporter
CLC90_RS12275	COG0163	prenyltransferase activity
CLC90_RS12280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLC90_RS12285	COG1286	toxin biosynthetic process
CLC90_RS12290	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CLC90_RS12295	COG0285	dihydrofolate synthase activity
CLC90_RS12305	COG0586	Pfam SNARE associated Golgi protein
CLC90_RS12315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLC90_RS12340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CLC90_RS12345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLC90_RS12375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CLC90_RS12390	COG3101	peptidyl-lysine hydroxylation
CLC90_RS12395	COG0730	response to heat
CLC90_RS12400	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CLC90_RS12410	COG2890	protein-(glutamine-N5) methyltransferase activity
CLC90_RS12415	COG2840	Smr protein MutS2
CLC90_RS12420	COG2062	phosphohistidine phosphatase, SixA
CLC90_RS12430	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLC90_RS12430	COG1024	Enoyl-CoA hydratase
CLC90_RS12435	COG0183	Belongs to the thiolase family
CLC90_RS12440	COG3691	Protein conserved in bacteria
CLC90_RS12455	COG4235	cytochrome complex assembly
CLC90_RS12455	COG3088	subunit of a heme lyase
CLC90_RS12460	COG3088	subunit of a heme lyase
CLC90_RS12460	COG4235	cytochrome complex assembly
CLC90_RS12465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CLC90_RS12470	COG1138	Cytochrome C-type biogenesis protein
CLC90_RS12475	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CLC90_RS12480	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLC90_RS12485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLC90_RS12495	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CLC90_RS12510	COG0582	viral genome integration into host DNA
CLC90_RS12515	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLC90_RS12570	COG2824	Alkylphosphonate utilization operon protein PhnA
CLC90_RS12575	COG2951	lytic endotransglycosylase activity
CLC90_RS12580	COG1598	PFAM Uncharacterised protein family UPF0150
CLC90_RS12590	COG3038	cytochrome b561
CLC90_RS12595	COG0436	Aminotransferase
CLC90_RS12605	COG3275	phosphorelay sensor kinase activity
CLC90_RS12610	COG3279	Response regulator of the LytR AlgR family
CLC90_RS12615	COG2223	nitrite transmembrane transporter activity
CLC90_RS12620	COG0837	glucose binding
CLC90_RS12640	COG1914	H( )-stimulated, divalent metal cation uptake system
CLC90_RS12645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLC90_RS12720	COG3530	Putative quorum-sensing-regulated virulence factor
CLC90_RS12725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLC90_RS12735	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CLC90_RS12745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLC90_RS12760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CLC90_RS12770	COG4208	sulfate ABC transporter
CLC90_RS12775	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CLC90_RS12780	COG4150	thiosulfate binding
CLC90_RS12790	COG1737	Transcriptional regulator
CLC90_RS12795	COG2731	YhcH YjgK YiaL family protein
CLC90_RS12810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLC90_RS12815	COG2837	iron assimilation
CLC90_RS12825	COG3111	PFAM Bacterial OB fold (BOF) protein
CLC90_RS12880	COG1671	Belongs to the UPF0178 family
CLC90_RS12885	COG0280	phosphate acetyltransferase
CLC90_RS12885	COG0281	malic enzyme
CLC90_RS12890	COG0494	nUDIX hydrolase
CLC90_RS12895	COG3005	denitrification pathway
CLC90_RS12900	COG3043	anaerobic respiration
CLC90_RS12905	COG0243	molybdopterin cofactor binding
CLC90_RS12910	COG3062	negative regulation of establishment of protein localization
CLC90_RS12915	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLC90_RS12915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLC90_RS12920	COG2197	response regulator
CLC90_RS12930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLC90_RS12940	COG1605	Chorismate mutase
CLC90_RS12945	COG1393	Belongs to the ArsC family
CLC90_RS12950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CLC90_RS12955	COG1876	peptidase activity
CLC90_RS12965	COG0400	carboxylic ester hydrolase activity
CLC90_RS12985	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CLC90_RS12990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLC90_RS12995	COG2716	regulation of RNA biosynthetic process
CLC90_RS13000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLC90_RS13005	COG0628	permease
CLC90_RS13010	COG4783	chaperone-mediated protein folding
CLC90_RS13015	COG1393	Belongs to the ArsC family
CLC90_RS13020	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLC90_RS13025	COG2233	PERMEase
CLC90_RS13030	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLC90_RS13035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CLC90_RS13040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLC90_RS13045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLC90_RS13055	COG0581	inorganic phosphate transmembrane transporter activity
CLC90_RS13060	COG0573	inorganic phosphate transmembrane transporter activity
CLC90_RS13065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CLC90_RS13080	COG2239	Acts as a magnesium transporter
CLC90_RS13085	COG0443	Heat shock 70 kDa protein
CLC90_RS13095	COG3121	Chaperone
CLC90_RS13115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLC90_RS13125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLC90_RS13130	COG0477	Major facilitator Superfamily
CLC90_RS13135	COG2205	protein histidine kinase activity
CLC90_RS13140	COG0745	RESPONSE REGULATOR receiver
CLC90_RS13145	COG3422	double-strand break repair
CLC90_RS13150	COG0826	peptidase U32
CLC90_RS13155	COG1597	lipid kinase activity
CLC90_RS13170	COG0351	phosphomethylpyrimidine kinase
CLC90_RS13185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CLC90_RS13185	COG0519	Catalyzes the synthesis of GMP from XMP
CLC90_RS13190	COG0516	GMP reductase activity
CLC90_RS13190	COG0517	IMP dehydrogenase activity
CLC90_RS13195	COG1570	exodeoxyribonuclease VII activity
CLC90_RS13200	COG1645	bacterial-type flagellum-dependent swarming motility
CLC90_RS13210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLC90_RS13215	COG2976	Protein conserved in bacteria
CLC90_RS13220	COG0124	histidyl-tRNA synthetase
CLC90_RS13255	COG4953	penicillin-binding protein 1C
CLC90_RS13260	COG2373	Large extracellular alpha-helical protein
CLC90_RS13275	COG2975	iron-sulfur cluster assembly
CLC90_RS13280	COG0633	Ferredoxin
CLC90_RS13285	COG0443	Heat shock 70 kDa protein
CLC90_RS13300	COG0822	iron-sulfur transferase activity
CLC90_RS13310	COG1959	2 iron, 2 sulfur cluster binding
CLC90_RS13315	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CLC90_RS13325	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CLC90_RS13330	COG3683	transport system, periplasmic component
CLC90_RS13335	COG3711	transcriptional antiterminator
CLC90_RS13340	COG2814	Major facilitator Superfamily
CLC90_RS13350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLC90_RS13350	COG1017	nitric oxide dioxygenase activity
CLC90_RS13355	COG2188	Transcriptional regulator
CLC90_RS13365	COG3457	Alanine racemase
CLC90_RS13370	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CLC90_RS13385	COG0347	Belongs to the P(II) protein family
CLC90_RS13390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLC90_RS13390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CLC90_RS13395	COG2204	response regulator
CLC90_RS13400	COG3170	Tfp pilus assembly protein FimV
CLC90_RS13405	COG2205	protein histidine kinase activity
CLC90_RS13420	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CLC90_RS13430	COG0560	Phosphoserine phosphatase
CLC90_RS13435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLC90_RS13435	COG1263	PTS System
CLC90_RS13445	COG1737	Transcriptional regulator
CLC90_RS13450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CLC90_RS13460	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CLC90_RS13470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLC90_RS13485	COG0481	GTPase activity
CLC90_RS13490	COG3086	response to oxidative stress
CLC90_RS13500	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CLC90_RS13510	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CLC90_RS13520	COG0513	Belongs to the DEAD box helicase family
CLC90_RS13535	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CLC90_RS13545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLC90_RS13550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLC90_RS13555	COG0497	DNA recombination
CLC90_RS13560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CLC90_RS13570	COG2867	negative regulation of translational initiation
CLC90_RS13575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLC90_RS13585	COG0582	viral genome integration into host DNA
CLC90_RS13620	COG3596	GTP binding
CLC90_RS13625	COG2378	regulation of single-species biofilm formation
CLC90_RS13635	COG2378	regulation of single-species biofilm formation
CLC90_RS13660	COG2003	Belongs to the UPF0758 family
CLC90_RS13715	COG3121	Chaperone
CLC90_RS13745	COG0583	DNA-binding transcription factor activity
CLC90_RS13815	COG1069	ribulokinase activity
CLC90_RS13825	COG1172	Belongs to the binding-protein-dependent transport system permease family
CLC90_RS13830	COG1129	ABC transporter
CLC90_RS13850	COG1620	l-lactate permease
CLC90_RS13855	COG1304	FMN binding
CLC90_RS13860	COG0579	oxidoreductase
CLC90_RS13865	COG1278	Cold shock
CLC90_RS13895	COG1780	Probably involved in ribonucleotide reductase function
CLC90_RS13900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLC90_RS13910	COG4175	Glycine betaine
CLC90_RS13915	COG4176	ABC-type proline glycine betaine transport system permease component
CLC90_RS13920	COG2113	Glycine betaine
CLC90_RS13930	COG2814	Major facilitator Superfamily
CLC90_RS13935	COG1846	Transcriptional regulator
CLC90_RS13945	COG1566	PFAM secretion protein HlyD family protein
CLC90_RS13950	COG2814	Major facilitator Superfamily
CLC90_RS13955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLC90_RS13960	COG3118	belongs to the thioredoxin family
CLC90_RS13965	COG3148	PFAM DTW domain containing protein
CLC90_RS13970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CLC90_RS13970	COG1042	CoA-binding domain protein
CLC90_RS13970	COG0045	succinate-CoA ligase (ADP-forming) activity
CLC90_RS13975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLC90_RS13980	COG5544	Lipoprotein
CLC90_RS14005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CLC90_RS14015	COG2011	ABC-type metal ion transport system permease component
CLC90_RS14020	COG1464	Belongs to the NlpA lipoprotein family
CLC90_RS14030	COG1720	tRNA m6t6A37 methyltransferase activity
CLC90_RS14035	COG0442	prolyl-tRNA aminoacylation
CLC90_RS14040	COG3015	lipoprotein NlpE involved in copper resistance
CLC90_RS14050	COG4681	YaeQ
CLC90_RS14060	COG4568	rho-dependent transcription termination
CLC90_RS14075	COG0346	lactoylglutathione lyase activity
CLC90_RS14095	COG0825	malonyl-CoA metabolic process
CLC90_RS14100	COG0587	DNA-directed DNA polymerase activity
CLC90_RS14105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLC90_RS14125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CLC90_RS14130	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CLC90_RS14140	COG0750	zinc metalloprotease
CLC90_RS14145	COG0575	Belongs to the CDS family
CLC90_RS14165	COG0528	UMP kinase activity
CLC90_RS14170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLC90_RS14185	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CLC90_RS14190	COG2171	N-acyltransferase activity
CLC90_RS14205	COG0564	pseudouridine synthase activity
CLC90_RS14210	COG3098	single-species biofilm formation
CLC90_RS14225	COG1611	Belongs to the LOG family
CLC90_RS14235	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CLC90_RS14240	COG2363	Small membrane protein
CLC90_RS14245	COG0583	DNA-binding transcription factor activity
CLC90_RS14255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLC90_RS14260	COG2166	iron-sulfur cluster assembly
CLC90_RS14265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CLC90_RS14270	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CLC90_RS14290	COG0860	N-Acetylmuramoyl-L-alanine amidase
CLC90_RS14295	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CLC90_RS14295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLC90_RS14300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CLC90_RS14305	COG1074	ATP-dependent DNA helicase activity
CLC90_RS14310	COG1025	Belongs to the peptidase M16 family
CLC90_RS14315	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CLC90_RS14320	COG4967	type IV pilus modification protein PilV
CLC90_RS14345	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLC90_RS14350	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CLC90_RS14365	COG3066	DNA modification
CLC90_RS14370	COG0861	Integral membrane protein TerC family
CLC90_RS14375	COG0667	Aldo Keto reductase
CLC90_RS14380	COG0477	Major facilitator Superfamily
CLC90_RS14385	COG0204	Acyl-transferase
CLC90_RS14385	COG0318	PFAM AMP-dependent synthetase and ligase
CLC90_RS14390	COG1609	Transcriptional regulator
CLC90_RS14400	COG0583	DNA-binding transcription factor activity
CLC90_RS14405	COG0583	DNA-binding transcription factor activity
CLC90_RS14460	COG2165	general secretion pathway protein
CLC90_RS14470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLC90_RS14500	COG1127	ABC transporter
CLC90_RS14505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLC90_RS14515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CLC90_RS14525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CLC90_RS14530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CLC90_RS14535	COG4974	Belongs to the 'phage' integrase family
CLC90_RS14540	COG0716	FMN binding
CLC90_RS14550	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CLC90_RS14560	COG1272	protein, Hemolysin III
CLC90_RS14580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CLC90_RS14585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLC90_RS14590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CLC90_RS14595	COG0006	proline dipeptidase activity
CLC90_RS14605	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CLC90_RS14615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLC90_RS14620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CLC90_RS14625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CLC90_RS14640	COG1279	arginine transmembrane transporter activity
CLC90_RS14650	COG0191	fructose-bisphosphate aldolase activity
CLC90_RS14655	COG0126	phosphoglycerate kinase activity
CLC90_RS14660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CLC90_RS14665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLC90_RS14675	COG1166	arginine decarboxylase activity
CLC90_RS14680	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLC90_RS14695	COG0640	Transcriptional regulator
CLC90_RS14700	COG3091	SprT-like family
CLC90_RS14705	COG2356	endonuclease I
CLC90_RS14710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CLC90_RS14715	COG0189	ligase activity
CLC90_RS14720	COG1678	Uncharacterized ACR, COG1678
CLC90_RS14725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLC90_RS14730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLC90_RS14740	COG2805	Type II/IV secretion system protein
CLC90_RS14745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLC90_RS14750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLC90_RS14755	COG0762	integral membrane protein
CLC90_RS14760	COG1872	DUF167
CLC90_RS14765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLC90_RS14770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CLC90_RS14785	COG3171	Protein conserved in bacteria
CLC90_RS14795	COG1194	a g-specific adenine glycosylase
CLC90_RS14800	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CLC90_RS14805	COG0741	lytic transglycosylase activity
CLC90_RS14845	COG1105	Belongs to the carbohydrate kinase PfkB family
CLC90_RS14850	COG1882	Formate acetyltransferase
CLC90_RS14855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLC90_RS14860	COG0814	amino acid
CLC90_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
CLC90_RS14880	COG1535	isochorismatase
CLC90_RS14880	COG3433	isochorismatase activity
CLC90_RS14885	COG1021	2,3-dihydroxybenzoate-AMP ligase
CLC90_RS14890	COG1169	isochorismate synthase
CLC90_RS14895	COG4592	Periplasmic binding protein
CLC90_RS14905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLC90_RS14910	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLC90_RS14915	COG1120	ATPase activity
CLC90_RS14925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CLC90_RS14930	COG3251	PFAM MbtH domain protein
CLC90_RS14940	COG4774	siderophore transport
CLC90_RS14945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLC90_RS14970	COG4964	Belongs to the GSP D family
CLC90_RS15030	COG0848	biopolymer transport protein
CLC90_RS15035	COG0811	peptide transport
CLC90_RS15040	COG0626	cystathionine gamma-synthase activity
CLC90_RS15045	COG0586	Pfam SNARE associated Golgi protein
CLC90_RS15050	COG2207	Transcriptional regulator
CLC90_RS15055	COG1979	alcohol dehydrogenase
CLC90_RS15060	COG0656	L-ascorbic acid biosynthetic process
CLC90_RS15070	COG2132	Multicopper oxidase
CLC90_RS15085	COG2249	NAD(P)H dehydrogenase (quinone) activity
CLC90_RS15090	COG0583	DNA-binding transcription factor activity
CLC90_RS15095	COG0187	DNA topoisomerase II activity
CLC90_RS15100	COG3150	esterase
CLC90_RS15105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CLC90_RS15110	COG3151	Protein conserved in bacteria
CLC90_RS15115	COG0494	nUDIX hydrolase
CLC90_RS15120	COG1538	Outer membrane efflux protein
CLC90_RS15125	COG5463	Belongs to the UPF0441 family
CLC90_RS15130	COG0754	glutathionylspermidine amidase activity
CLC90_RS15135	COG3384	dioxygenase
CLC90_RS15140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLC90_RS15155	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CLC90_RS15155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CLC90_RS15165	COG3025	triphosphatase activity
CLC90_RS15170	COG4991	sh3 domain protein
CLC90_RS15175	COG0617	tRNA 3'-terminal CCA addition
CLC90_RS15180	COG1968	undecaprenyl-diphosphatase activity
CLC90_RS15185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLC90_RS15190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CLC90_RS15195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLC90_RS15200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CLC90_RS15205	COG0358	DNA primase activity
CLC90_RS15235	COG1028	Short-chain dehydrogenase reductase Sdr
CLC90_RS15270	COG0463	Glycosyl transferase, family 2
CLC90_RS15295	COG3210	domain, Protein
CLC90_RS15315	COG3210	domain, Protein
CLC90_RS15320	COG2831	hemolysin activation secretion protein
CLC90_RS15325	COG1902	pentaerythritol trinitrate reductase activity
CLC90_RS15325	COG0446	pyridine nucleotide-disulphide oxidoreductase
CLC90_RS15340	COG1451	nucleotide metabolic process
CLC90_RS15345	COG0673	inositol 2-dehydrogenase activity
CLC90_RS15350	COG0861	Integral membrane protein TerC family
CLC90_RS15355	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CLC90_RS15365	COG2721	sulfolactate sulfo-lyase activity
CLC90_RS15380	COG2271	Major facilitator Superfamily
CLC90_RS15395	COG0586	Pfam SNARE associated Golgi protein
CLC90_RS15410	COG4575	ribosome binding
CLC90_RS15415	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CLC90_RS15425	COG2259	Doxx family
CLC90_RS15430	COG0583	DNA-binding transcription factor activity
CLC90_RS15435	COG1741	Belongs to the pirin family
CLC90_RS15450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLC90_RS15465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CLC90_RS15470	COG2823	Periplasmic or secreted lipoprotein
CLC90_RS15475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CLC90_RS15480	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CLC90_RS15490	COG0784	Response regulator, receiver
CLC90_RS15490	COG2198	Histidine kinase
CLC90_RS15490	COG5002	protein histidine kinase activity
CLC90_RS15495	COG1242	4 iron, 4 sulfur cluster binding
CLC90_RS15500	COG0067	glutamate synthase
CLC90_RS15500	COG0069	glutamate synthase activity
CLC90_RS15500	COG0070	glutamate synthase
CLC90_RS15505	COG0493	'glutamate synthase
CLC90_RS15515	COG2969	positive regulation of protein catabolic process
CLC90_RS15520	COG0625	glutathione transferase activity
CLC90_RS15525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CLC90_RS15530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLC90_RS15540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CLC90_RS15545	COG3105	Protein conserved in bacteria
CLC90_RS15550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLC90_RS15560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLC90_RS15565	COG5007	Belongs to the BolA IbaG family
CLC90_RS15570	COG3113	response to antibiotic
CLC90_RS15575	COG2854	intermembrane phospholipid transfer
CLC90_RS15580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CLC90_RS15585	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CLC90_RS15590	COG1127	ABC transporter
CLC90_RS15595	COG0530	calcium, potassium:sodium antiporter activity
CLC90_RS15600	COG0517	IMP dehydrogenase activity
CLC90_RS15600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CLC90_RS15605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CLC90_RS15610	COG3117	lipopolysaccharide transmembrane transporter activity
CLC90_RS15615	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CLC90_RS15620	COG1137	ATPase activity
CLC90_RS15625	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CLC90_RS15645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CLC90_RS15650	COG0540	Belongs to the ATCase OTCase family
CLC90_RS15655	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CLC90_RS15665	COG0366	Alpha amylase catalytic
CLC90_RS15670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CLC90_RS15670	COG1263	PTS System
CLC90_RS15680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CLC90_RS15690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CLC90_RS15695	COG3783	Cytochrome b(562)
CLC90_RS15700	COG0312	modulator of DNA gyrase
CLC90_RS15705	COG3028	Belongs to the UPF0307 family
CLC90_RS15710	COG2732	(Barnase) inhibitor
CLC90_RS15715	COG4290	ribonuclease
CLC90_RS15725	COG1289	transmembrane transporter activity
CLC90_RS15730	COG1566	PFAM secretion protein HlyD family protein
CLC90_RS15740	COG0583	DNA-binding transcription factor activity
CLC90_RS15745	COG0312	modulator of DNA gyrase
CLC90_RS15750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CLC90_RS15755	COG3164	Protein of unknown function
CLC90_RS15765	COG0424	maF-like protein
CLC90_RS15770	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CLC90_RS15775	COG1792	Involved in formation and maintenance of cell shape
CLC90_RS15780	COG1077	Cell shape determining protein MreB Mrl
CLC90_RS15785	COG2199	diguanylate cyclase activity
CLC90_RS15785	COG2200	EAL domain
CLC90_RS15790	COG0604	alcohol dehydrogenase
CLC90_RS15795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLC90_RS15800	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CLC90_RS15810	COG0511	ligase activity, forming carbon-carbon bonds
CLC90_RS15815	COG0439	Biotin carboxylase
CLC90_RS15820	COG3924	membrane
CLC90_RS15825	COG4145	pantothenate transmembrane transporter activity
CLC90_RS15830	COG2264	protein methyltransferase activity
CLC90_RS15835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLC90_RS15840	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CLC90_RS15850	COG1560	Kdo2-lipid A biosynthetic process
CLC90_RS15860	COG1346	cytolysis
CLC90_RS15865	COG1380	Effector of murein hydrolase LrgA
CLC90_RS15870	COG0583	DNA-binding transcription factor activity
CLC90_RS15875	COG0025	NhaP-type Na H and K H
CLC90_RS15880	COG2252	PERMEase
CLC90_RS15895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CLC90_RS15900	COG2315	Protein conserved in bacteria
CLC90_RS15905	COG1448	Aminotransferase
CLC90_RS15930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLC90_RS15935	COG0735	belongs to the Fur family
CLC90_RS15940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLC90_RS15945	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CLC90_RS15950	COG2937	Belongs to the GPAT DAPAT family
CLC90_RS15970	COG4580	involved in the transport of maltose and maltodextrins
CLC90_RS15985	COG2182	Extracellular solute-binding protein
CLC90_RS15990	COG1175	transmembrane transport
CLC90_RS15995	COG3833	ABC-type maltose transport systems, permease component
CLC90_RS16000	COG3223	Belongs to the PsiE family
CLC90_RS16010	COG0527	aspartate kinase activity
CLC90_RS16025	COG3328	transposase activity
CLC90_RS16055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLC90_RS16140	COG0583	DNA-binding transcription factor activity
CLC90_RS16180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CLC90_RS16225	COG0138	bifunctional purine biosynthesis protein purh
CLC90_RS16230	COG0151	Belongs to the GarS family
CLC90_RS16250	COG1515	deoxyribonuclease V activity
CLC90_RS16255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLC90_RS16260	COG2816	NAD+ diphosphatase activity
CLC90_RS16265	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CLC90_RS16280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CLC90_RS16285	COG2104	thiamine diphosphate biosynthetic process
CLC90_RS16290	COG2022	thiamine diphosphate biosynthetic process
CLC90_RS16300	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLC90_RS16305	COG0085	RNA polymerase activity
CLC90_RS16310	COG0222	ribosome binding
CLC90_RS16315	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLC90_RS16325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLC90_RS16330	COG0250	Participates in transcription elongation, termination and antitermination
CLC90_RS16375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CLC90_RS16400	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CLC90_RS16405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CLC90_RS16410	COG1739	Uncharacterized protein family UPF0029
CLC90_RS16420	COG1250	3-hydroxyacyl-CoA dehydrogenase
CLC90_RS16420	COG1024	Enoyl-CoA hydratase
CLC90_RS16430	COG0543	2 iron, 2 sulfur cluster binding
CLC90_RS16445	COG0250	Participates in transcription elongation, termination and antitermination
CLC90_RS16460	COG0805	protein transport
CLC90_RS16465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLC90_RS16470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLC90_RS16475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CLC90_RS16480	COG3165	ubiquinone biosynthetic process from chorismate
CLC90_RS16485	COG2226	methyltransferase
CLC90_RS16490	COG1322	Protein conserved in bacteria
CLC90_RS16495	COG0586	Pfam SNARE associated Golgi protein
CLC90_RS16500	COG1966	Carbon starvation protein
CLC90_RS16515	COG0412	Dienelactone hydrolase
CLC90_RS16520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLC90_RS16525	COG0583	DNA-binding transcription factor activity
CLC90_RS16530	COG0697	spore germination
CLC90_RS16540	COG0584	glycerophosphoryl diester phosphodiesterase
CLC90_RS16550	COG0395	ABC-type sugar transport system, permease component
CLC90_RS16555	COG1175	transmembrane transport
CLC90_RS16560	COG1653	transport
CLC90_RS16595	COG0410	ABC transporter
CLC90_RS16605	COG4177	L-phenylalanine transmembrane transporter activity
CLC90_RS16625	COG1929	Belongs to the glycerate kinase type-1 family
CLC90_RS16630	COG2610	gluconate transmembrane transporter activity
CLC90_RS16635	COG3835	regulator
CLC90_RS16645	COG2177	Part of the ABC transporter FtsEX involved in
CLC90_RS16650	COG2884	Cell division ATP-binding protein ftsE
CLC90_RS16655	COG0552	protein localization to endoplasmic reticulum
CLC90_RS16655	COG0552	protein localization to endoplasmic reticulum
CLC90_RS16660	COG0742	ribosomal rna small subunit methyltransferase
CLC90_RS16665	COG3776	membrane
CLC90_RS16680	COG3714	YhhN family
CLC90_RS16695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLC90_RS16705	COG0247	lactate metabolic process
CLC90_RS16715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLC90_RS16725	COG2271	Major facilitator Superfamily
CLC90_RS16730	COG0584	glycerophosphoryl diester phosphodiesterase
CLC90_RS16735	COG0561	phosphatase activity
CLC90_RS16740	COG2267	carboxylic ester hydrolase activity
CLC90_RS16745	COG1280	lysine exporter protein (LysE YggA)
CLC90_RS16750	COG0514	ATP-dependent DNA helicase (RecQ)
CLC90_RS16755	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CLC90_RS16760	COG2050	protein possibly involved in aromatic compounds catabolism
CLC90_RS16780	COG5564	TIM-barrel signal transduction protein
CLC90_RS16785	COG5441	Belongs to the UPF0261 family
CLC90_RS16795	COG0210	DNA helicase
CLC90_RS16800	COG1011	Hydrolase
CLC90_RS16805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CLC90_RS16810	COG3159	Protein conserved in bacteria
CLC90_RS16815	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLC90_RS16820	COG5567	small periplasmic lipoprotein
CLC90_RS16830	COG3072	Adenylate cyclase
CLC90_RS16835	COG0181	hydroxymethylbilane synthase activity
CLC90_RS16840	COG1587	Uroporphyrinogen-III synthase
CLC90_RS16845	COG2959	enzyme of heme biosynthesis
CLC90_RS16850	COG3071	HemY protein
CLC90_RS16900	COG2244	polysaccharide biosynthetic process
CLC90_RS16905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CLC90_RS16910	COG0456	acetyltransferase
CLC90_RS16915	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLC90_RS16920	COG1088	dTDP-glucose 4,6-dehydratase activity
CLC90_RS16925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CLC90_RS16930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CLC90_RS16935	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CLC90_RS16940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLC90_RS16945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLC90_RS16950	COG3118	belongs to the thioredoxin family
CLC90_RS16960	COG0248	Ppx GppA phosphatase
CLC90_RS16970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CLC90_RS16985	COG3397	chitin binding
CLC90_RS16995	COG0129	dihydroxy-acid dehydratase activity
CLC90_RS17010	COG3978	acetolactate synthase activity
CLC90_RS17030	COG3085	chromosome segregation
CLC90_RS17035	COG0583	DNA-binding transcription factor activity
CLC90_RS17110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLC90_RS17120	COG0678	peroxiredoxin activity
CLC90_RS17120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CLC90_RS17125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CLC90_RS17160	COG1629	transport
CLC90_RS17165	COG0165	Argininosuccinate lyase
CLC90_RS17170	COG0137	argininosuccinate synthase activity
CLC90_RS17175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CLC90_RS17235	COG1454	alcohol dehydrogenase
CLC90_RS17355	COG0741	lytic transglycosylase activity
CLC90_RS17515	COG2944	sequence-specific DNA binding
CLC90_RS17595	COG1192	Involved in chromosome partitioning