locus-tag	class	description
FFE93_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFE93_RS00010	COG0592	DNA-directed DNA polymerase activity
FFE93_RS00020	COG0187	DNA topoisomerase II activity
FFE93_RS00025	COG0561	phosphatase activity
FFE93_RS00035	COG0751	glycine-tRNA ligase activity
FFE93_RS00045	COG2818	Glycosylase
FFE93_RS00050	COG0456	acetyltransferase
FFE93_RS00060	COG2885	chlorophyll binding
FFE93_RS00080	COG0366	Alpha amylase catalytic
FFE93_RS00085	COG3977	Valine--pyruvate aminotransferase
FFE93_RS00090	COG2985	domain, Protein
FFE93_RS00090	COG0569	domain protein
FFE93_RS00105	COG5645	(Lipo)protein
FFE93_RS00110	COG0823	Involved in the tonB-independent uptake of proteins
FFE93_RS00120	COG3727	T/G mismatch-specific endonuclease activity
FFE93_RS00140	COG2423	ornithine cyclodeaminase activity
FFE93_RS00145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_RS00145	COG2213	PTS system mannitol-specific
FFE93_RS00150	COG0246	Mannitol dehydrogenase
FFE93_RS00155	COG3722	fumarate hydratase activity
FFE93_RS00165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE93_RS00180	COG3077	Addiction module antitoxin, RelB DinJ family
FFE93_RS00185	COG2258	MOSC domain
FFE93_RS00190	COG0840	transmembrane signaling receptor activity
FFE93_RS00200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FFE93_RS00205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FFE93_RS00215	COG0437	4 iron, 4 sulfur cluster binding
FFE93_RS00220	COG2864	formate dehydrogenase
FFE93_RS00230	COG1921	L-seryl-tRNASec selenium transferase activity
FFE93_RS00235	COG3276	selenocysteine insertion sequence binding
FFE93_RS00240	COG3622	Belongs to the hyi family
FFE93_RS00255	COG3274	enterobacterial common antigen metabolic process
FFE93_RS00270	COG1070	Carbohydrate kinase
FFE93_RS00275	COG2115	Belongs to the xylose isomerase family
FFE93_RS00280	COG4213	ABC transporter substrate-binding protein
FFE93_RS00290	COG4214	carbohydrate transport
FFE93_RS00295	COG2207	Transcriptional regulator
FFE93_RS00295	COG1609	Transcriptional regulator
FFE93_RS00310	COG1393	Belongs to the ArsC family
FFE93_RS00335	COG1561	YicC-like family, N-terminal region
FFE93_RS00340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FFE93_RS00345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FFE93_RS00350	COG1301	dicarboxylic acid transport
FFE93_RS00355	COG0612	Peptidase, M16
FFE93_RS00360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE93_RS00365	COG1942	4-Oxalocrotonate Tautomerase
FFE93_RS00370	COG2200	EAL domain
FFE93_RS00375	COG2982	Protein involved in outer membrane biogenesis
FFE93_RS00380	COG2134	cdp-diacylglycerol pyrophosphatase
FFE93_RS00385	COG1295	ribonuclease BN
FFE93_RS00395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE93_RS00400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FFE93_RS00410	COG0742	ribosomal rna small subunit methyltransferase
FFE93_RS00430	COG0583	DNA-binding transcription factor activity
FFE93_RS00465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFE93_RS00480	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FFE93_RS00485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE93_RS00510	COG2814	Major facilitator Superfamily
FFE93_RS00525	COG0589	response to stress
FFE93_RS00535	COG0306	phosphate transporter
FFE93_RS00540	COG2081	HI0933 family
FFE93_RS00585	COG1247	-acetyltransferase
FFE93_RS00590	COG1741	Belongs to the pirin family
FFE93_RS00595	COG1609	Transcriptional regulator
FFE93_RS00600	COG2610	gluconate transmembrane transporter activity
FFE93_RS00605	COG3265	gluconokinase activity
FFE93_RS00610	COG2095	MarC family integral membrane protein
FFE93_RS00615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FFE93_RS00620	COG3275	phosphorelay sensor kinase activity
FFE93_RS00625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FFE93_RS00630	COG1523	belongs to the glycosyl hydrolase 13 family
FFE93_RS00640	COG0297	glycogen (starch) synthase activity
FFE93_RS00645	COG0058	SHG alpha-glucan phosphorylase activity
FFE93_RS00650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FFE93_RS00655	COG1349	DNA-binding transcription factor activity
FFE93_RS00660	COG0705	Rhomboid family
FFE93_RS00680	COG2909	trisaccharide binding
FFE93_RS00685	COG0058	SHG alpha-glucan phosphorylase activity
FFE93_RS00690	COG1640	4-alpha-glucanotransferase
FFE93_RS00695	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FFE93_RS00695	COG0316	Belongs to the HesB IscA family
FFE93_RS00700	COG1040	competence protein
FFE93_RS00705	COG0596	Alpha beta hydrolase
FFE93_RS00715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FFE93_RS00720	COG1918	ferrous iron import across plasma membrane
FFE93_RS00725	COG2183	response to ionizing radiation
FFE93_RS00735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFE93_RS00755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FFE93_RS00765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FFE93_RS00770	COG1011	Hydrolase
FFE93_RS00780	COG0494	nUDIX hydrolase
FFE93_RS00785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FFE93_RS00810	COG4796	Type ii and iii secretion system protein
FFE93_RS00815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFE93_RS00835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FFE93_RS00845	COG0180	Tryptophanyl-tRNA synthetase
FFE93_RS00850	COG1648	precorrin-2 dehydrogenase activity
FFE93_RS00850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFE93_RS00865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFE93_RS00870	COG0402	S-adenosylhomocysteine deaminase activity
FFE93_RS00875	COG0738	Major facilitator superfamily
FFE93_RS00895	COG1486	melibiose metabolic process
FFE93_RS00900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FFE93_RS00905	COG0433	COG0433 Predicted ATPase
FFE93_RS00920	COG1289	transmembrane transporter activity
FFE93_RS00930	COG1765	OsmC-like protein
FFE93_RS00935	COG3954	Phosphoribulokinase
FFE93_RS00940	COG3089	Belongs to the UPF0270 family
FFE93_RS00945	COG0429	hydrolase of the alpha beta-hydrolase fold
FFE93_RS00960	COG4521	taurine ABC transporter
FFE93_RS00970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFE93_RS00975	COG2175	clavaminate synthase activity
FFE93_RS00980	COG1216	Glycosyl transferase, family 2
FFE93_RS00985	COG0488	(ABC) transporter
FFE93_RS00990	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFE93_RS01000	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FFE93_RS01005	COG1047	Peptidyl-prolyl cis-trans
FFE93_RS01015	COG0545	Peptidyl-prolyl cis-trans isomerase
FFE93_RS01020	COG2964	Protein conserved in bacteria
FFE93_RS01025	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FFE93_RS01035	COG2168	tRNA wobble position uridine thiolation
FFE93_RS01040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FFE93_RS01045	COG0049	tRNA binding
FFE93_RS01055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFE93_RS01075	COG0051	transcription antitermination factor activity, RNA binding
FFE93_RS01080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FFE93_RS01090	COG0089	rRNA binding
FFE93_RS01095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FFE93_RS01100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FFE93_RS01105	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FFE93_RS01110	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FFE93_RS01115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FFE93_RS01120	COG0255	Belongs to the universal ribosomal protein uL29 family
FFE93_RS01125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FFE93_RS01130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FFE93_RS01145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFE93_RS01155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FFE93_RS01160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FFE93_RS01165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FFE93_RS01170	COG1841	ribosomal large subunit assembly
FFE93_RS01175	COG0200	Binds to the 23S rRNA
FFE93_RS01180	COG0201	protein transport
FFE93_RS01185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FFE93_RS01190	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FFE93_RS01195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FFE93_RS01200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFE93_RS01210	COG0203	ribosomal protein L17
FFE93_RS01220	COG0789	Transcriptional regulator
FFE93_RS01225	COG3036	rescue of stalled ribosome
FFE93_RS01230	COG1970	mechanosensitive ion channel activity
FFE93_RS01240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FFE93_RS01240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFE93_RS01245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFE93_RS01250	COG0242	peptide deformylase activity
FFE93_RS01255	COG0758	DNA mediated transformation
FFE93_RS01265	COG0551	DNA topoisomerase type I activity
FFE93_RS01270	COG0009	L-threonylcarbamoyladenylate synthase
FFE93_RS01275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFE93_RS01280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FFE93_RS01325	COG1072	(Pantothenic acid kinase))
FFE93_RS01375	COG0250	Participates in transcription elongation, termination and antitermination
FFE93_RS01380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FFE93_RS01385	COG0081	regulation of translation
FFE93_RS01390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FFE93_RS01395	COG0222	ribosome binding
FFE93_RS01400	COG0085	RNA polymerase activity
FFE93_RS01405	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FFE93_RS01425	COG2022	thiamine diphosphate biosynthetic process
FFE93_RS01430	COG2104	thiamine diphosphate biosynthetic process
FFE93_RS01435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FFE93_RS01450	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FFE93_RS01455	COG2816	NAD+ diphosphatase activity
FFE93_RS01465	COG1515	deoxyribonuclease V activity
FFE93_RS01485	COG0151	Belongs to the GarS family
FFE93_RS01535	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FFE93_RS01540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FFE93_RS01550	COG2224	Isocitrate lyase
FFE93_RS01555	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FFE93_RS01560	COG1414	Transcriptional regulator
FFE93_RS01580	COG0527	aspartate kinase activity
FFE93_RS01585	COG0166	Belongs to the GPI family
FFE93_RS01590	COG3223	Belongs to the PsiE family
FFE93_RS01595	COG3833	ABC-type maltose transport systems, permease component
FFE93_RS01600	COG1175	transmembrane transport
FFE93_RS01630	COG3161	chorismate lyase activity
FFE93_RS01640	COG2937	Belongs to the GPAT DAPAT family
FFE93_RS01645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FFE93_RS01650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FFE93_RS01655	COG3237	CsbD-like
FFE93_RS01660	COG0735	belongs to the Fur family
FFE93_RS01665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFE93_RS01680	COG0604	alcohol dehydrogenase
FFE93_RS01695	COG1448	Aminotransferase
FFE93_RS01700	COG2315	Protein conserved in bacteria
FFE93_RS01705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FFE93_RS01730	COG2252	PERMEase
FFE93_RS01735	COG0025	NhaP-type Na H and K H
FFE93_RS01750	COG1126	abc transporter atp-binding protein
FFE93_RS01755	COG0765	amino acid transport
FFE93_RS01760	COG4597	amino acid ABC transporter
FFE93_RS01765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS01770	COG1560	Kdo2-lipid A biosynthetic process
FFE93_RS01780	COG1129	ABC transporter
FFE93_RS01785	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS01795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE93_RS01805	COG0471	metal ion transport
FFE93_RS01810	COG1278	Cold shock
FFE93_RS01815	COG1278	Cold shock
FFE93_RS01820	COG3133	Outer membrane lipoprotein
FFE93_RS01825	COG3706	GGDEF domain
FFE93_RS01830	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FFE93_RS01835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFE93_RS01840	COG2264	protein methyltransferase activity
FFE93_RS01845	COG4145	pantothenate transmembrane transporter activity
FFE93_RS01850	COG3924	membrane
FFE93_RS01855	COG0439	Biotin carboxylase
FFE93_RS01860	COG0511	ligase activity, forming carbon-carbon bonds
FFE93_RS01865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FFE93_RS01870	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FFE93_RS01880	COG0604	alcohol dehydrogenase
FFE93_RS01885	COG2200	EAL domain
FFE93_RS01885	COG2199	diguanylate cyclase activity
FFE93_RS01890	COG1077	Cell shape determining protein MreB Mrl
FFE93_RS01895	COG1792	Involved in formation and maintenance of cell shape
FFE93_RS01900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FFE93_RS01905	COG0424	maF-like protein
FFE93_RS01910	COG1530	ribonuclease E activity
FFE93_RS01915	COG3164	Protein of unknown function
FFE93_RS01920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFE93_RS01925	COG0312	modulator of DNA gyrase
FFE93_RS01930	COG0583	DNA-binding transcription factor activity
FFE93_RS01940	COG1566	PFAM secretion protein HlyD family protein
FFE93_RS01945	COG1289	transmembrane transporter activity
FFE93_RS01950	COG1012	belongs to the aldehyde dehydrogenase family
FFE93_RS01960	COG2732	(Barnase) inhibitor
FFE93_RS01965	COG3028	Belongs to the UPF0307 family
FFE93_RS01970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FFE93_RS02040	COG4695	Portal protein
FFE93_RS02200	COG3344	reverse transcriptase
FFE93_RS02210	COG0312	modulator of DNA gyrase
FFE93_RS02215	COG3783	Cytochrome b(562)
FFE93_RS02220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFE93_RS02250	COG3964	amidohydrolase
FFE93_RS02265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_RS02265	COG3711	transcriptional antiterminator
FFE93_RS02270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FFE93_RS02280	COG1263	PTS System
FFE93_RS02280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS02285	COG0366	Alpha amylase catalytic
FFE93_RS02305	COG2308	Evidence 4 Homologs of previously reported genes of
FFE93_RS02315	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FFE93_RS02320	COG0540	Belongs to the ATCase OTCase family
FFE93_RS02325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_RS02345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FFE93_RS02350	COG1137	ATPase activity
FFE93_RS02355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FFE93_RS02360	COG3117	lipopolysaccharide transmembrane transporter activity
FFE93_RS02365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FFE93_RS02370	COG0517	IMP dehydrogenase activity
FFE93_RS02370	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FFE93_RS02375	COG0530	calcium, potassium:sodium antiporter activity
FFE93_RS02380	COG1127	ABC transporter
FFE93_RS02385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FFE93_RS02390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FFE93_RS02395	COG2854	intermembrane phospholipid transfer
FFE93_RS02400	COG3113	response to antibiotic
FFE93_RS02405	COG5007	Belongs to the BolA IbaG family
FFE93_RS02415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE93_RS02420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE93_RS02425	COG3105	Protein conserved in bacteria
FFE93_RS02430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FFE93_RS02435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FFE93_RS02440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FFE93_RS02450	COG0625	glutathione transferase activity
FFE93_RS02455	COG2969	positive regulation of protein catabolic process
FFE93_RS02470	COG0493	'glutamate synthase
FFE93_RS02475	COG0070	glutamate synthase
FFE93_RS02475	COG0069	glutamate synthase activity
FFE93_RS02475	COG0067	glutamate synthase
FFE93_RS02480	COG1242	4 iron, 4 sulfur cluster binding
FFE93_RS02485	COG2198	Histidine kinase
FFE93_RS02485	COG5002	protein histidine kinase activity
FFE93_RS02485	COG0784	Response regulator, receiver
FFE93_RS02495	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FFE93_RS02500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFE93_RS02505	COG2823	Periplasmic or secreted lipoprotein
FFE93_RS02510	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FFE93_RS02515	COG0792	nuclease activity
FFE93_RS02525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FFE93_RS02565	COG1064	alcohol dehydrogenase
FFE93_RS02570	COG1741	Belongs to the pirin family
FFE93_RS02575	COG0583	DNA-binding transcription factor activity
FFE93_RS02580	COG0435	Glutathione S-transferase
FFE93_RS02585	COG2259	Doxx family
FFE93_RS02595	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FFE93_RS02600	COG4575	ribosome binding
FFE93_RS02615	COG0586	Pfam SNARE associated Golgi protein
FFE93_RS02630	COG2271	Major facilitator Superfamily
FFE93_RS02635	COG1904	glucuronate isomerase
FFE93_RS02640	COG0246	Mannitol dehydrogenase
FFE93_RS02645	COG2721	sulfolactate sulfo-lyase activity
FFE93_RS02655	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FFE93_RS02660	COG0861	Integral membrane protein TerC family
FFE93_RS02665	COG0673	inositol 2-dehydrogenase activity
FFE93_RS02670	COG1451	nucleotide metabolic process
FFE93_RS02680	COG2813	Specifically methylates the guanine in position
FFE93_RS02690	COG1902	pentaerythritol trinitrate reductase activity
FFE93_RS02690	COG0446	pyridine nucleotide-disulphide oxidoreductase
FFE93_RS02695	COG3247	response to pH
FFE93_RS02730	COG1815	bacterial-type flagellum-dependent cell motility
FFE93_RS02735	COG1558	bacterial-type flagellum-dependent cell motility
FFE93_RS02740	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FFE93_RS02745	COG1749	Flagellar hook protein flgE
FFE93_RS02770	COG1705	Flagellar rod assembly protein muramidase FlgJ
FFE93_RS02770	COG3951	Flagellar rod assembly protein muramidase FlgJ
FFE93_RS02780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFE93_RS02785	COG0840	transmembrane signaling receptor activity
FFE93_RS02815	COG0643	Histidine kinase
FFE93_RS02815	COG2198	Histidine kinase
FFE93_RS02820	COG0835	chemotaxis
FFE93_RS02825	COG0840	transmembrane signaling receptor activity
FFE93_RS02860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFE93_RS02875	COG0745	RESPONSE REGULATOR receiver
FFE93_RS02885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FFE93_RS02890	COG1677	Flagellar hook-basal body complex protein FliE
FFE93_RS02895	COG1766	The M ring may be actively involved in energy transduction
FFE93_RS02925	COG1580	Controls the rotational direction of flagella during chemotaxis
FFE93_RS02960	COG2197	response regulator
FFE93_RS02965	COG0840	transmembrane signaling receptor activity
FFE93_RS02980	COG0358	DNA primase activity
FFE93_RS02985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FFE93_RS02990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FFE93_RS02995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FFE93_RS03000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FFE93_RS03005	COG1968	undecaprenyl-diphosphatase activity
FFE93_RS03010	COG0617	tRNA 3'-terminal CCA addition
FFE93_RS03015	COG4991	sh3 domain protein
FFE93_RS03020	COG3025	triphosphatase activity
FFE93_RS03025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FFE93_RS03030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FFE93_RS03030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FFE93_RS03035	COG0531	amino acid
FFE93_RS03045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFE93_RS03050	COG3384	dioxygenase
FFE93_RS03055	COG0754	glutathionylspermidine amidase activity
FFE93_RS03060	COG5463	Belongs to the UPF0441 family
FFE93_RS03065	COG1538	Outer membrane efflux protein
FFE93_RS03070	COG0494	nUDIX hydrolase
FFE93_RS03075	COG3151	Protein conserved in bacteria
FFE93_RS03080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FFE93_RS03085	COG3150	esterase
FFE93_RS03090	COG0187	DNA topoisomerase II activity
FFE93_RS03095	COG0583	DNA-binding transcription factor activity
FFE93_RS03100	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FFE93_RS03105	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFE93_RS03120	COG0204	Acyl-transferase
FFE93_RS03125	COG2132	Multicopper oxidase
FFE93_RS03135	COG0656	L-ascorbic acid biosynthetic process
FFE93_RS03140	COG1979	alcohol dehydrogenase
FFE93_RS03145	COG2207	Transcriptional regulator
FFE93_RS03150	COG0586	Pfam SNARE associated Golgi protein
FFE93_RS03165	COG0848	biopolymer transport protein
FFE93_RS03215	COG4964	Belongs to the GSP D family
FFE93_RS03240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_RS03245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS03270	COG1120	ATPase activity
FFE93_RS03275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE93_RS03280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE93_RS03285	COG4592	Periplasmic binding protein
FFE93_RS03290	COG1595	DNA-templated transcription, initiation
FFE93_RS03295	COG3712	iron ion homeostasis
FFE93_RS03300	COG4771	TonB-dependent receptor
FFE93_RS03305	COG0612	Peptidase, M16
FFE93_RS03310	COG4178	(ABC) transporter
FFE93_RS03315	COG0840	transmembrane signaling receptor activity
FFE93_RS03335	COG3133	Outer membrane lipoprotein
FFE93_RS03340	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FFE93_RS03345	COG0437	4 iron, 4 sulfur cluster binding
FFE93_RS03350	COG5557	Pfam Polysulphide reductase, NrfD
FFE93_RS03355	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FFE93_RS03360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FFE93_RS03365	COG1773	rubredoxin
FFE93_RS03375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FFE93_RS03380	COG0298	carbon dioxide binding
FFE93_RS03385	COG0409	Hydrogenase expression formation protein
FFE93_RS03390	COG0309	Hydrogenase expression formation protein (HypE)
FFE93_RS03395	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FFE93_RS03400	COG5001	Diguanylate cyclase
FFE93_RS03410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS03420	COG0477	Major facilitator Superfamily
FFE93_RS03430	COG1283	sodium-dependent phosphate transmembrane transporter activity
FFE93_RS03440	COG1609	Transcriptional regulator
FFE93_RS03450	COG4607	ABC-type enterochelin transport system periplasmic component
FFE93_RS03460	COG4605	iron ion homeostasis
FFE93_RS03465	COG4604	ABC transporter, ATP-binding protein
FFE93_RS03480	COG2831	hemolysin activation secretion protein
FFE93_RS03565	COG1289	transmembrane transporter activity
FFE93_RS03575	COG0288	reversible hydration of carbon dioxide
FFE93_RS03665	COG1360	Flagellar Motor Protein
FFE93_RS03725	COG2771	luxR family
FFE93_RS03735	COG0583	DNA-binding transcription factor activity
FFE93_RS03745	COG1388	LysM domain
FFE93_RS03745	COG4932	domain protein
FFE93_RS03745	COG2373	Large extracellular alpha-helical protein
FFE93_RS03775	COG0582	viral genome integration into host DNA
FFE93_RS03810	COG3539	Fimbrial protein
FFE93_RS03825	COG0583	DNA-binding transcription factor activity
FFE93_RS03880	COG1982	Orn Lys Arg decarboxylase major
FFE93_RS03890	COG0741	lytic transglycosylase activity
FFE93_RS03900	COG1194	a g-specific adenine glycosylase
FFE93_RS03905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FFE93_RS03910	COG3171	Protein conserved in bacteria
FFE93_RS03965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE93_RS04005	COG2184	nucleotidyltransferase activity
FFE93_RS04075	COG4695	Portal protein
FFE93_RS04140	COG4974	Belongs to the 'phage' integrase family
FFE93_RS04155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFE93_RS04160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FFE93_RS04165	COG1872	DUF167
FFE93_RS04170	COG0762	integral membrane protein
FFE93_RS04175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFE93_RS04180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FFE93_RS04185	COG2805	Type II/IV secretion system protein
FFE93_RS04195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFE93_RS04200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FFE93_RS04205	COG1678	Uncharacterized ACR, COG1678
FFE93_RS04210	COG0189	ligase activity
FFE93_RS04215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FFE93_RS04220	COG2356	endonuclease I
FFE93_RS04225	COG3091	SprT-like family
FFE93_RS04235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FFE93_RS04240	COG1166	arginine decarboxylase activity
FFE93_RS04250	COG0501	Belongs to the peptidase M48B family
FFE93_RS04255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FFE93_RS04265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FFE93_RS04270	COG0126	phosphoglycerate kinase activity
FFE93_RS04275	COG0191	fructose-bisphosphate aldolase activity
FFE93_RS04280	COG3344	reverse transcriptase
FFE93_RS04290	COG1279	arginine transmembrane transporter activity
FFE93_RS04300	COG0583	DNA-binding transcription factor activity
FFE93_RS04305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FFE93_RS04310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFE93_RS04315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FFE93_RS04325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FFE93_RS04330	COG3079	Belongs to the UPF0149 family
FFE93_RS04335	COG0006	proline dipeptidase activity
FFE93_RS04340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFE93_RS04345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFE93_RS04350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFE93_RS04360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFE93_RS04360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFE93_RS04365	COG1272	protein, Hemolysin III
FFE93_RS04370	COG0354	folic acid binding
FFE93_RS04385	COG0745	RESPONSE REGULATOR receiver
FFE93_RS04390	COG2205	protein histidine kinase activity
FFE93_RS04395	COG4452	Inner membrane protein CreD
FFE93_RS04400	COG0716	FMN binding
FFE93_RS04405	COG4974	Belongs to the 'phage' integrase family
FFE93_RS04410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FFE93_RS04415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FFE93_RS04425	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FFE93_RS04455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FFE93_RS04455	COG1215	transferase activity, transferring glycosyl groups
FFE93_RS04480	COG3706	GGDEF domain
FFE93_RS04485	COG1522	sequence-specific DNA binding
FFE93_RS04500	COG2271	Major facilitator Superfamily
FFE93_RS04510	COG0484	heat shock protein binding
FFE93_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS04525	COG1733	regulation of RNA biosynthetic process
FFE93_RS04545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FFE93_RS04565	COG4795	General secretion pathway protein
FFE93_RS04615	COG0583	DNA-binding transcription factor activity
FFE93_RS04620	COG2814	Major facilitator Superfamily
FFE93_RS04625	COG0583	DNA-binding transcription factor activity
FFE93_RS04635	COG1609	Transcriptional regulator
FFE93_RS04645	COG0204	Acyl-transferase
FFE93_RS04645	COG0318	PFAM AMP-dependent synthetase and ligase
FFE93_RS04650	COG0477	Major facilitator Superfamily
FFE93_RS04660	COG0667	Aldo Keto reductase
FFE93_RS04665	COG0861	Integral membrane protein TerC family
FFE93_RS04680	COG1051	belongs to the nudix hydrolase family
FFE93_RS04690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FFE93_RS04720	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FFE93_RS04725	COG1025	Belongs to the peptidase M16 family
FFE93_RS04730	COG1074	ATP-dependent DNA helicase activity
FFE93_RS04735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FFE93_RS04740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FFE93_RS04740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FFE93_RS04745	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE93_RS04765	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FFE93_RS04770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FFE93_RS04775	COG2166	iron-sulfur cluster assembly
FFE93_RS04780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FFE93_RS04790	COG0583	DNA-binding transcription factor activity
FFE93_RS04795	COG2363	Small membrane protein
FFE93_RS04800	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FFE93_RS04810	COG1611	Belongs to the LOG family
FFE93_RS04815	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FFE93_RS04815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FFE93_RS04825	COG3098	single-species biofilm formation
FFE93_RS04830	COG0564	pseudouridine synthase activity
FFE93_RS04850	COG2171	N-acyltransferase activity
FFE93_RS04855	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FFE93_RS04865	COG0052	Belongs to the universal ribosomal protein uS2 family
FFE93_RS04870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FFE93_RS04875	COG0528	UMP kinase activity
FFE93_RS04880	COG0233	cytoplasmic translational termination
FFE93_RS04885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FFE93_RS04895	COG0575	Belongs to the CDS family
FFE93_RS04900	COG0750	zinc metalloprotease
FFE93_RS04910	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FFE93_RS04915	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFE93_RS04925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFE93_RS04935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FFE93_RS04940	COG0587	DNA-directed DNA polymerase activity
FFE93_RS04945	COG0825	malonyl-CoA metabolic process
FFE93_RS04950	COG0346	lactoylglutathione lyase activity
FFE93_RS04965	COG4568	rho-dependent transcription termination
FFE93_RS04975	COG4681	YaeQ
FFE93_RS04985	COG3015	lipoprotein NlpE involved in copper resistance
FFE93_RS04995	COG1720	tRNA m6t6A37 methyltransferase activity
FFE93_RS05005	COG1464	Belongs to the NlpA lipoprotein family
FFE93_RS05010	COG2011	ABC-type metal ion transport system permease component
FFE93_RS05020	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FFE93_RS05050	COG0656	L-ascorbic acid biosynthetic process
FFE93_RS05060	COG3021	interspecies interaction between organisms
FFE93_RS05065	COG1388	LysM domain
FFE93_RS05065	COG0741	lytic transglycosylase activity
FFE93_RS05070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE93_RS05075	COG2226	methyltransferase
FFE93_RS05080	COG0328	RNA-DNA hybrid ribonuclease activity
FFE93_RS05095	COG2113	Glycine betaine
FFE93_RS05100	COG4176	ABC-type proline glycine betaine transport system permease component
FFE93_RS05105	COG4175	Glycine betaine
FFE93_RS05110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE93_RS05120	COG1780	Probably involved in ribonucleotide reductase function
FFE93_RS05125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFE93_RS05130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFE93_RS05140	COG4575	ribosome binding
FFE93_RS05165	COG1278	Cold shock
FFE93_RS05175	COG0601	transmembrane transport
FFE93_RS05180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_RS05200	COG0831	urea catabolic process
FFE93_RS05205	COG0832	Belongs to the urease beta subunit family
FFE93_RS05210	COG0804	urea catabolic process
FFE93_RS05225	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FFE93_RS05235	COG4413	Urea transporter
FFE93_RS05240	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FFE93_RS05250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FFE93_RS05265	COG2133	pyrroloquinoline quinone binding
FFE93_RS05270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE93_RS05275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE93_RS05280	COG2723	6-phospho-beta-galactosidase activity
FFE93_RS05285	COG1447	Phosphotransferase system cellobiose-specific component IIA
FFE93_RS05290	COG2169	Transcriptional regulator
FFE93_RS05290	COG1917	Cupin 2, conserved barrel domain protein
FFE93_RS05295	COG3394	polysaccharide catabolic process
FFE93_RS05305	COG3344	reverse transcriptase
FFE93_RS05390	COG0582	viral genome integration into host DNA
FFE93_RS05400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FFE93_RS05405	COG2867	negative regulation of translational initiation
FFE93_RS05415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFE93_RS05420	COG0497	DNA recombination
FFE93_RS05425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FFE93_RS05430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FFE93_RS05435	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FFE93_RS05440	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FFE93_RS05445	COG0513	Belongs to the DEAD box helicase family
FFE93_RS05450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FFE93_RS05455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FFE93_RS05465	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FFE93_RS05475	COG3086	response to oxidative stress
FFE93_RS05485	COG0481	GTPase activity
FFE93_RS05500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FFE93_RS05505	COG1381	Involved in DNA repair and RecF pathway recombination
FFE93_RS05510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FFE93_RS05520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_RS05525	COG1737	Transcriptional regulator
FFE93_RS05535	COG1263	PTS System
FFE93_RS05535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS05540	COG0560	Phosphoserine phosphatase
FFE93_RS05555	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FFE93_RS05570	COG2205	protein histidine kinase activity
FFE93_RS05575	COG3170	Tfp pilus assembly protein FimV
FFE93_RS05580	COG2204	response regulator
FFE93_RS05585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFE93_RS05585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FFE93_RS05590	COG0347	Belongs to the P(II) protein family
FFE93_RS05605	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FFE93_RS05610	COG3457	Alanine racemase
FFE93_RS05620	COG2188	Transcriptional regulator
FFE93_RS05625	COG1017	nitric oxide dioxygenase activity
FFE93_RS05625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE93_RS05635	COG2814	Major facilitator Superfamily
FFE93_RS05640	COG3711	transcriptional antiterminator
FFE93_RS05645	COG3683	transport system, periplasmic component
FFE93_RS05650	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FFE93_RS05655	COG0483	inositol monophosphate 1-phosphatase activity
FFE93_RS05660	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FFE93_RS05675	COG0822	iron-sulfur transferase activity
FFE93_RS05690	COG0443	Heat shock 70 kDa protein
FFE93_RS05695	COG0633	Ferredoxin
FFE93_RS05700	COG2975	iron-sulfur cluster assembly
FFE93_RS05715	COG3468	outer membrane autotransporter barrel domain protein
FFE93_RS05720	COG2373	Large extracellular alpha-helical protein
FFE93_RS05725	COG4953	penicillin-binding protein 1C
FFE93_RS05765	COG2976	Protein conserved in bacteria
FFE93_RS05770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFE93_RS05775	COG1160	GTP binding
FFE93_RS05785	COG1645	bacterial-type flagellum-dependent swarming motility
FFE93_RS05790	COG1570	exodeoxyribonuclease VII activity
FFE93_RS05795	COG0517	IMP dehydrogenase activity
FFE93_RS05795	COG0516	GMP reductase activity
FFE93_RS05800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FFE93_RS05800	COG0519	Catalyzes the synthesis of GMP from XMP
FFE93_RS05810	COG0351	phosphomethylpyrimidine kinase
FFE93_RS05825	COG0517	IMP dehydrogenase activity
FFE93_RS05825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FFE93_RS05830	COG1349	DNA-binding transcription factor activity
FFE93_RS05835	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS05855	COG3730	PTS system glucitol sorbitol-specific
FFE93_RS05860	COG1597	lipid kinase activity
FFE93_RS05865	COG0826	peptidase U32
FFE93_RS05870	COG3422	double-strand break repair
FFE93_RS05875	COG0745	RESPONSE REGULATOR receiver
FFE93_RS05880	COG2205	protein histidine kinase activity
FFE93_RS05885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_RS05895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS05900	COG0443	Heat shock 70 kDa protein
FFE93_RS05905	COG5001	Diguanylate cyclase
FFE93_RS05905	COG5002	protein histidine kinase activity
FFE93_RS05905	COG3447	MASE1 domain protein
FFE93_RS05910	COG2239	Acts as a magnesium transporter
FFE93_RS05920	COG0248	Ppx GppA phosphatase
FFE93_RS05925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FFE93_RS05930	COG0573	inorganic phosphate transmembrane transporter activity
FFE93_RS05935	COG0581	inorganic phosphate transmembrane transporter activity
FFE93_RS05955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE93_RS05960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FFE93_RS05975	COG2233	PERMEase
FFE93_RS05980	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFE93_RS05985	COG1393	Belongs to the ArsC family
FFE93_RS05990	COG4783	chaperone-mediated protein folding
FFE93_RS05995	COG0628	permease
FFE93_RS06000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FFE93_RS06005	COG2716	regulation of RNA biosynthetic process
FFE93_RS06010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFE93_RS06015	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FFE93_RS06020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FFE93_RS06025	COG2321	neutral zinc metallopeptidase
FFE93_RS06030	COG2707	UPF0756 membrane protein
FFE93_RS06035	COG1444	tRNA N-acetyltransferase activity
FFE93_RS06040	COG0400	carboxylic ester hydrolase activity
FFE93_RS06050	COG1876	peptidase activity
FFE93_RS06055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFE93_RS06060	COG1393	Belongs to the ArsC family
FFE93_RS06075	COG1175	transmembrane transport
FFE93_RS06080	COG3842	ATPase activity
FFE93_RS06090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_RS06100	COG2197	response regulator
FFE93_RS06105	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_RS06105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_RS06110	COG3062	negative regulation of establishment of protein localization
FFE93_RS06115	COG0243	molybdopterin cofactor binding
FFE93_RS06120	COG3043	anaerobic respiration
FFE93_RS06125	COG3005	denitrification pathway
FFE93_RS06150	COG1671	Belongs to the UPF0178 family
FFE93_RS06155	COG0408	coproporphyrinogen oxidase activity
FFE93_RS06160	COG0456	acetyltransferase
FFE93_RS06170	COG3111	PFAM Bacterial OB fold (BOF) protein
FFE93_RS06180	COG2837	iron assimilation
FFE93_RS06185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFE93_RS06200	COG2731	YhcH YjgK YiaL family protein
FFE93_RS06205	COG1737	Transcriptional regulator
FFE93_RS06220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FFE93_RS06225	COG4208	sulfate ABC transporter
FFE93_RS06245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS06250	COG0745	RESPONSE REGULATOR receiver
FFE93_RS06255	COG2205	protein histidine kinase activity
FFE93_RS06270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_RS06330	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FFE93_RS06340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FFE93_RS06345	COG3530	Putative quorum-sensing-regulated virulence factor
FFE93_RS06375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFE93_RS06405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE93_RS06410	COG1914	H( )-stimulated, divalent metal cation uptake system
FFE93_RS06420	COG0667	Aldo Keto reductase
FFE93_RS06435	COG0837	glucose binding
FFE93_RS06440	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FFE93_RS06450	COG2223	nitrite transmembrane transporter activity
FFE93_RS06455	COG3279	Response regulator of the LytR AlgR family
FFE93_RS06460	COG3275	phosphorelay sensor kinase activity
FFE93_RS06475	COG0436	Aminotransferase
FFE93_RS06480	COG3038	cytochrome b561
FFE93_RS06490	COG1598	PFAM Uncharacterised protein family UPF0150
FFE93_RS06530	COG2951	lytic endotransglycosylase activity
FFE93_RS06535	COG0531	amino acid
FFE93_RS06555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FFE93_RS06560	COG1127	ABC transporter
FFE93_RS06575	COG3038	cytochrome b561
FFE93_RS06580	COG2353	YceI-like domain
FFE93_RS06585	COG1609	Transcriptional regulator
FFE93_RS06590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS06590	COG1263	PTS System
FFE93_RS06595	COG2723	6-phospho-beta-galactosidase activity
FFE93_RS06605	COG1695	Transcriptional regulator
FFE93_RS06610	COG2824	Alkylphosphonate utilization operon protein PhnA
FFE93_RS06625	COG2116	formate transmembrane transporter activity
FFE93_RS06635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFE93_RS06640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFE93_RS06645	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFE93_RS06650	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FFE93_RS06655	COG1138	Cytochrome C-type biogenesis protein
FFE93_RS06660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE93_RS06665	COG3088	subunit of a heme lyase
FFE93_RS06665	COG4235	cytochrome complex assembly
FFE93_RS06670	COG4235	cytochrome complex assembly
FFE93_RS06670	COG3088	subunit of a heme lyase
FFE93_RS06685	COG3691	Protein conserved in bacteria
FFE93_RS06690	COG0183	Belongs to the thiolase family
FFE93_RS06695	COG1024	Enoyl-CoA hydratase
FFE93_RS06695	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFE93_RS06700	COG2062	phosphohistidine phosphatase, SixA
FFE93_RS06710	COG2840	Smr protein MutS2
FFE93_RS06715	COG2890	protein-(glutamine-N5) methyltransferase activity
FFE93_RS06725	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FFE93_RS06730	COG0730	response to heat
FFE93_RS06735	COG3101	peptidyl-lysine hydroxylation
FFE93_RS06745	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FFE93_RS06745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFE93_RS06750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE93_RS06760	COG1794	racemase activity, acting on amino acids and derivatives
FFE93_RS06785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE93_RS06790	COG0697	spore germination
FFE93_RS06815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FFE93_RS06825	COG0586	Pfam SNARE associated Golgi protein
FFE93_RS06835	COG0285	dihydrofolate synthase activity
FFE93_RS06840	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FFE93_RS06845	COG1286	toxin biosynthetic process
FFE93_RS06850	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FFE93_RS06860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS06865	COG4215	(ABC) transporter
FFE93_RS06870	COG4160	amino acid transport
FFE93_RS06885	COG1090	epimerase
FFE93_RS06895	COG0622	Phosphoesterase
FFE93_RS06900	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FFE93_RS06905	COG0561	phosphatase activity
FFE93_RS06910	COG2706	6-phosphogluconolactonase activity
FFE93_RS06920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FFE93_RS06925	COG0156	8-amino-7-oxononanoate synthase activity
FFE93_RS06930	COG2226	methyltransferase
FFE93_RS06945	COG0556	nucleotide-excision repair
FFE93_RS06950	COG4628	conserved protein (DUF2132)
FFE93_RS06955	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FFE93_RS06960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FFE93_RS06965	COG0315	cyclic pyranopterin monophosphate synthase activity
FFE93_RS06970	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FFE93_RS06975	COG0314	molybdopterin synthase activity
FFE93_RS06980	COG0670	Belongs to the BI1 family
FFE93_RS06985	COG0842	Transport permease protein
FFE93_RS06990	COG0842	Transport permease protein
FFE93_RS06995	COG1131	(ABC) transporter
FFE93_RS07000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS07005	COG1309	transcriptional regulator
FFE93_RS07010	COG0513	Belongs to the DEAD box helicase family
FFE93_RS07015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFE93_RS07030	COG1686	Belongs to the peptidase S11 family
FFE93_RS07035	COG0277	FAD linked oxidase domain protein
FFE93_RS07055	COG2261	transglycosylase associated protein
FFE93_RS07065	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FFE93_RS07080	COG4807	Protein conserved in bacteria
FFE93_RS07100	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FFE93_RS07110	COG2897	thiosulfate sulfurtransferase activity
FFE93_RS07160	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FFE93_RS07180	COG0681	Belongs to the peptidase S26 family
FFE93_RS07200	COG4626	Terminase
FFE93_RS07200	COG1802	Transcriptional regulator
FFE93_RS07205	COG4725	Belongs to the MT-A70-like family
FFE93_RS07215	COG3645	SOS response
FFE93_RS07215	COG3646	Phage regulatory protein
FFE93_RS07220	COG1403	HNH endonuclease
FFE93_RS07240	COG3772	lysozyme
FFE93_RS07265	COG1802	Transcriptional regulator
FFE93_RS07265	COG4626	Terminase
FFE93_RS07275	COG4695	Portal protein
FFE93_RS07320	COG4386	tail sheath protein
FFE93_RS07370	COG3299	homolog of phage Mu protein gp47
FFE93_RS07375	COG3778	Protein conserved in bacteria
FFE93_RS07405	COG3082	Protein of unknown function (DUF1414)
FFE93_RS07410	COG3081	Nucleoid-associated protein
FFE93_RS07420	COG1061	Type III restriction enzyme res subunit
FFE93_RS07425	COG1187	pseudouridine synthase activity
FFE93_RS07430	COG2814	Major facilitator Superfamily
FFE93_RS07440	COG4172	Belongs to the ABC transporter superfamily
FFE93_RS07445	COG4239	(ABC) transporter, permease
FFE93_RS07450	COG4174	ABC transporter (Permease)
FFE93_RS07455	COG4166	transmembrane transport
FFE93_RS07460	COG2200	EAL domain
FFE93_RS07465	COG0791	NLP P60 protein
FFE93_RS07470	COG0671	phosphoesterase, PA-phosphatase related
FFE93_RS07475	COG0523	cobalamin synthesis protein
FFE93_RS07485	COG2186	Transcriptional regulator
FFE93_RS07490	COG0246	Mannitol dehydrogenase
FFE93_RS07505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FFE93_RS07520	COG0243	molybdopterin cofactor binding
FFE93_RS07525	COG3005	denitrification pathway
FFE93_RS07540	COG1105	Belongs to the carbohydrate kinase PfkB family
FFE93_RS07545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFE93_RS07545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFE93_RS07545	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FFE93_RS07550	COG3344	reverse transcriptase
FFE93_RS07555	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FFE93_RS07560	COG2855	membrane
FFE93_RS07570	COG0583	DNA-binding transcription factor activity
FFE93_RS07575	COG0833	amino acid
FFE93_RS07590	COG4771	TonB-dependent receptor
FFE93_RS07595	COG0625	glutathione transferase activity
FFE93_RS07620	COG2011	ABC-type metal ion transport system permease component
FFE93_RS07635	COG0626	cystathionine gamma-synthase activity
FFE93_RS07645	COG1686	Belongs to the peptidase S11 family
FFE93_RS07650	COG1760	l-serine dehydratase
FFE93_RS07655	COG0814	amino acid
FFE93_RS07660	COG1349	DNA-binding transcription factor activity
FFE93_RS07670	COG0671	phosphoesterase, PA-phosphatase related
FFE93_RS07750	COG4695	Portal protein
FFE93_RS07775	COG0569	domain protein
FFE93_RS07775	COG2985	domain, Protein
FFE93_RS07800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FFE93_RS07805	COG3842	ATPase activity
FFE93_RS07810	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFE93_RS07815	COG1177	transmembrane transport
FFE93_RS07830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS07835	COG4160	amino acid transport
FFE93_RS07840	COG4215	(ABC) transporter
FFE93_RS07845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS07850	COG1126	abc transporter atp-binding protein
FFE93_RS07855	COG1605	Chorismate mutase
FFE93_RS07865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE93_RS07870	COG0702	epimerase
FFE93_RS07875	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FFE93_RS07880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FFE93_RS07885	COG0028	Belongs to the TPP enzyme family
FFE93_RS07890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE93_RS07895	COG1151	hydroxylamine reductase activity
FFE93_RS07900	COG2431	L-lysine efflux transmembrane transporter activity
FFE93_RS07905	COG3593	DNA synthesis involved in DNA repair
FFE93_RS07910	COG2990	Protein conserved in bacteria
FFE93_RS07915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS07925	COG1278	Cold shock
FFE93_RS07930	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FFE93_RS07935	COG0542	response to heat
FFE93_RS07940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FFE93_RS07945	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FFE93_RS07950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FFE93_RS07960	COG0492	ferredoxin-NADP+ reductase activity
FFE93_RS07970	COG3107	peptidoglycan biosynthetic process
FFE93_RS07970	COG1674	ftsk spoiiie
FFE93_RS07975	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FFE93_RS07980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FFE93_RS07985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FFE93_RS07990	COG2814	Major facilitator Superfamily
FFE93_RS07995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FFE93_RS08000	COG1882	Formate acetyltransferase
FFE93_RS08005	COG2116	formate transmembrane transporter activity
FFE93_RS08010	COG1944	ATP diphosphatase activity
FFE93_RS08015	COG0252	asparaginase activity
FFE93_RS08020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FFE93_RS08025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FFE93_RS08035	COG0539	negative regulation of cytoplasmic translation
FFE93_RS08040	COG0776	regulation of translation
FFE93_RS08045	COG2333	competence protein COMEC
FFE93_RS08045	COG0658	competence protein
FFE93_RS08060	COG5383	Protein conserved in bacteria
FFE93_RS08070	COG1278	Cold shock
FFE93_RS08075	COG2835	tetraacyldisaccharide 4'-kinase activity
FFE93_RS08085	COG3173	Aminoglycoside phosphotransferase
FFE93_RS08090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FFE93_RS08095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFE93_RS08100	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FFE93_RS08115	COG2989	Protein conserved in bacteria
FFE93_RS08120	COG3108	Peptidase M15
FFE93_RS08125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE93_RS08130	COG2200	EAL domain
FFE93_RS08135	COG1448	Aminotransferase
FFE93_RS08145	COG0017	Asparaginyl-tRNA synthetase
FFE93_RS08150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FFE93_RS08155	COG0308	aminopeptidase N
FFE93_RS08160	COG0167	dihydroorotate dehydrogenase activity
FFE93_RS08170	COG0633	Ferredoxin
FFE93_RS08170	COG3217	Mosc domain protein beta barrel domain protein
FFE93_RS08175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FFE93_RS08175	COG0116	Belongs to the methyltransferase superfamily
FFE93_RS08180	COG0488	(ABC) transporter
FFE93_RS08185	COG2995	paraquat-inducible protein a
FFE93_RS08190	COG3008	intermembrane lipid transfer
FFE93_RS08190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FFE93_RS08195	COG3009	Protein conserved in bacteria
FFE93_RS08200	COG3130	regulation of translation
FFE93_RS08205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE93_RS08215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FFE93_RS08220	COG1067	ATP-dependent peptidase activity
FFE93_RS08225	COG3120	sequence-specific DNA binding
FFE93_RS08235	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FFE93_RS08240	COG3070	regulator of competence-specific genes
FFE93_RS08245	COG1289	transmembrane transporter activity
FFE93_RS08250	COG3304	Inner membrane component domain
FFE93_RS08255	COG0210	DNA helicase
FFE93_RS08270	COG1832	CoA-binding protein
FFE93_RS08275	COG3785	DNA binding
FFE93_RS08285	COG1254	Belongs to the acylphosphatase family
FFE93_RS08290	COG2920	part of a sulfur-relay system
FFE93_RS08315	COG0463	Glycosyl transferase, family 2
FFE93_RS08350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE93_RS08350	COG0543	2 iron, 2 sulfur cluster binding
FFE93_RS08390	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FFE93_RS08395	COG0437	4 iron, 4 sulfur cluster binding
FFE93_RS08400	COG3301	Polysulphide reductase, NrfD
FFE93_RS08405	COG1138	Cytochrome C-type biogenesis protein
FFE93_RS08410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE93_RS08415	COG3088	subunit of a heme lyase
FFE93_RS08420	COG4235	cytochrome complex assembly
FFE93_RS08425	COG2771	luxR family
FFE93_RS08430	COG3916	Acyl-homoserine-lactone synthase
FFE93_RS08440	COG3263	regulation of cellular component size
FFE93_RS08455	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FFE93_RS08460	COG2943	transferase activity, transferring hexosyl groups
FFE93_RS08465	COG5645	(Lipo)protein
FFE93_RS08480	COG2259	Doxx family
FFE93_RS08485	COG1560	Kdo2-lipid A biosynthetic process
FFE93_RS08525	COG0628	permease
FFE93_RS08555	COG0418	dihydroorotase activity
FFE93_RS08560	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FFE93_RS08565	COG1530	ribonuclease E activity
FFE93_RS08570	COG0564	pseudouridine synthase activity
FFE93_RS08580	COG1399	metal-binding, possibly nucleic acid-binding protein
FFE93_RS08585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FFE93_RS08590	COG0416	fatty acid biosynthetic process
FFE93_RS08600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FFE93_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS08615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE93_RS08620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFE93_RS08625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FFE93_RS08630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FFE93_RS08635	COG0470	DNA polymerase III
FFE93_RS08640	COG0084	hydrolase, TatD family'
FFE93_RS08645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS08645	COG1263	PTS System
FFE93_RS08665	COG0641	radical SAM
FFE93_RS08675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFE93_RS08680	COG0537	adenosine 5'-monophosphoramidase activity
FFE93_RS08685	COG5633	Lipoprotein
FFE93_RS08690	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FFE93_RS08705	COG3150	esterase
FFE93_RS08710	COG1252	NADH dehydrogenase
FFE93_RS08715	COG3134	Outer membrane lipoprotein
FFE93_RS08720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FFE93_RS08725	COG4591	ABC-type transport system involved in lipoprotein release permease component
FFE93_RS08735	COG4591	ABC-type transport system involved in lipoprotein release permease component
FFE93_RS08740	COG1940	carbohydrate kinase activity
FFE93_RS08760	COG2850	peptidyl-arginine hydroxylation
FFE93_RS08770	COG0745	RESPONSE REGULATOR receiver
FFE93_RS08775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FFE93_RS08780	COG2915	High frequency lysogenization protein hflD homolog
FFE93_RS08785	COG0482	sulfurtransferase activity
FFE93_RS08795	COG1187	pseudouridine synthase activity
FFE93_RS08800	COG0538	isocitrate dehydrogenase activity
FFE93_RS08810	COG0561	phosphatase activity
FFE93_RS08825	COG3493	citrate carrier protein
FFE93_RS08830	COG4565	transcriptional regulatory protein
FFE93_RS08835	COG3290	protein histidine kinase activity
FFE93_RS08840	COG2066	Belongs to the glutaminase family
FFE93_RS08850	COG1609	Transcriptional regulator
FFE93_RS08855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE93_RS08860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE93_RS08865	COG2723	6-phospho-beta-galactosidase activity
FFE93_RS08870	COG1447	Phosphotransferase system cellobiose-specific component IIA
FFE93_RS08880	COG0672	)-iron permease
FFE93_RS08895	COG1136	(ABC) transporter
FFE93_RS08895	COG0577	efflux transmembrane transporter activity
FFE93_RS08905	COG1136	(ABC) transporter
FFE93_RS08905	COG0577	efflux transmembrane transporter activity
FFE93_RS08925	COG4114	ferric iron reductase
FFE93_RS08930	COG0006	proline dipeptidase activity
FFE93_RS08935	COG0457	Tetratricopeptide repeat
FFE93_RS08940	COG1649	PFAM Uncharacterised BCR, COG1649
FFE93_RS08940	COG0726	polysaccharide deacetylase
FFE93_RS08945	COG1215	transferase activity, transferring glycosyl groups
FFE93_RS08950	COG3658	cytochrome
FFE93_RS08965	COG1702	phosphate starvation-inducible protein PhoH
FFE93_RS08970	COG0387	Pfam Sodium calcium exchanger
FFE93_RS08985	COG0583	DNA-binding transcription factor activity
FFE93_RS08990	COG3850	Histidine kinase
FFE93_RS09000	COG1294	oxidase, subunit
FFE93_RS09005	COG1271	oxidase subunit
FFE93_RS09010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE93_RS09015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFE93_RS09020	COG3138	arginine N-succinyltransferase
FFE93_RS09030	COG3724	N-succinylarginine dihydrolase activity
FFE93_RS09035	COG2988	succinylglutamate desuccinylase activity
FFE93_RS09050	COG1228	amidohydrolase
FFE93_RS09060	COG0402	S-adenosylhomocysteine deaminase activity
FFE93_RS09070	COG3443	Belongs to the bacterial solute-binding protein 9 family
FFE93_RS09080	COG4942	peptidase
FFE93_RS09085	COG0667	Aldo Keto reductase
FFE93_RS09090	COG0656	L-ascorbic acid biosynthetic process
FFE93_RS09120	COG1073	alpha beta
FFE93_RS09130	COG0012	GTP binding
FFE93_RS09140	COG0193	aminoacyl-tRNA hydrolase activity
FFE93_RS09150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FFE93_RS09160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FFE93_RS09165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FFE93_RS09175	COG2890	protein-(glutamine-N5) methyltransferase activity
FFE93_RS09195	COG0659	secondary active sulfate transmembrane transporter activity
FFE93_RS09200	COG3706	GGDEF domain
FFE93_RS09215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFE93_RS09225	COG3381	protein complex oligomerization
FFE93_RS09235	COG0477	Major facilitator Superfamily
FFE93_RS09240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE93_RS09250	COG0673	inositol 2-dehydrogenase activity
FFE93_RS09265	COG3102	Protein conserved in bacteria
FFE93_RS09270	COG3142	Participates in the control of copper homeostasis
FFE93_RS09280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFE93_RS09290	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FFE93_RS09295	COG1335	isochorismatase
FFE93_RS09305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FFE93_RS09310	COG0494	nUDIX hydrolase
FFE93_RS09315	COG0217	transcriptional regulatory protein
FFE93_RS09325	COG0632	four-way junction helicase activity
FFE93_RS09330	COG2255	four-way junction helicase activity
FFE93_RS09335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE93_RS09340	COG1121	(ABC) transporter
FFE93_RS09345	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FFE93_RS09350	COG0739	heme binding
FFE93_RS09355	COG1560	Kdo2-lipid A biosynthetic process
FFE93_RS09360	COG0469	pyruvate kinase activity
FFE93_RS09365	COG1737	Transcriptional regulator
FFE93_RS09370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FFE93_RS09375	COG0800	Aldolase
FFE93_RS09380	COG2076	Multidrug Resistance protein
FFE93_RS09385	COG2076	Multidrug Resistance protein
FFE93_RS09390	COG0251	oxidation-reduction process
FFE93_RS09395	COG1199	ATP-dependent helicase activity
FFE93_RS09405	COG3065	identical protein binding
FFE93_RS09410	COG0318	PFAM AMP-dependent synthetase and ligase
FFE93_RS09415	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FFE93_RS09420	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FFE93_RS09425	COG2894	cell division
FFE93_RS09430	COG0850	regulation of cytokinetic process
FFE93_RS09440	COG0179	Fumarylacetoacetate (FAA) hydrolase
FFE93_RS09445	COG2983	Belongs to the UPF0260 family
FFE93_RS09460	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FFE93_RS09465	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFE93_RS09475	COG2186	Transcriptional regulator
FFE93_RS09480	COG4139	cobalamin transport
FFE93_RS09485	COG0386	Belongs to the glutathione peroxidase family
FFE93_RS09490	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FFE93_RS09495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFE93_RS09500	COG0463	Glycosyl transferase, family 2
FFE93_RS09510	COG0726	polysaccharide deacetylase
FFE93_RS09515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFE93_RS09520	COG2076	Multidrug Resistance protein
FFE93_RS09525	COG2076	Multidrug Resistance protein
FFE93_RS09530	COG0791	NLP P60 protein
FFE93_RS09535	COG0095	Lipoate-protein ligase
FFE93_RS09545	COG4771	TonB-dependent receptor
FFE93_RS09560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FFE93_RS09570	COG0574	Belongs to the PEP-utilizing enzyme family
FFE93_RS09570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFE93_RS09580	COG0628	permease
FFE93_RS09585	COG0247	lactate metabolic process
FFE93_RS09585	COG0277	FAD linked oxidase domain protein
FFE93_RS09590	COG2050	protein possibly involved in aromatic compounds catabolism
FFE93_RS09600	COG0316	Belongs to the HesB IscA family
FFE93_RS09605	COG0719	Fe-S assembly protein
FFE93_RS09610	COG0396	ATPase activity
FFE93_RS09615	COG0719	Fe-S assembly protein
FFE93_RS09625	COG2166	iron-sulfur cluster assembly
FFE93_RS09630	COG1376	ErfK ybiS ycfS ynhG family protein
FFE93_RS09630	COG1388	LysM domain
FFE93_RS09655	COG0534	Mate efflux family protein
FFE93_RS09660	COG0307	riboflavin synthase, alpha
FFE93_RS09665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FFE93_RS09670	COG2814	Major facilitator Superfamily
FFE93_RS09675	COG0583	DNA-binding transcription factor activity
FFE93_RS09680	COG1609	Transcriptional regulator
FFE93_RS09695	COG0791	NLP P60 protein
FFE93_RS09700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FFE93_RS09705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFE93_RS09710	COG0346	lactoylglutathione lyase activity
FFE93_RS09715	COG1902	pentaerythritol trinitrate reductase activity
FFE93_RS09720	COG1309	transcriptional regulator
FFE93_RS09725	COG2194	sulfuric ester hydrolase activity
FFE93_RS09730	COG3313	Fe-S protein
FFE93_RS09735	COG4989	oxidoreductase activity
FFE93_RS09750	COG1846	Transcriptional regulator
FFE93_RS09755	COG3133	Outer membrane lipoprotein
FFE93_RS09760	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FFE93_RS09765	COG3895	Periplasmic Protein
FFE93_RS09775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FFE93_RS09785	COG0625	glutathione transferase activity
FFE93_RS09805	COG3104	oligopeptide transport
FFE93_RS09810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFE93_RS09810	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFE93_RS09820	COG4172	Belongs to the ABC transporter superfamily
FFE93_RS09830	COG4171	peptide transport system, permease
FFE93_RS09835	COG4168	peptide transport system, permease
FFE93_RS09840	COG4166	transmembrane transport
FFE93_RS09850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FFE93_RS09855	COG1842	Phage shock protein A
FFE93_RS09865	COG1983	PspC domain protein
FFE93_RS09875	COG3106	COG3106 Predicted ATPase
FFE93_RS09880	COG3768	UPF0283 membrane protein
FFE93_RS09885	COG5654	RES domain protein
FFE93_RS09890	COG5642	Protein of unknown function (DUF2384)
FFE93_RS09900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FFE93_RS09905	COG4948	Mandelate Racemase Muconate Lactonizing
FFE93_RS09910	COG2866	Carboxypeptidase
FFE93_RS09915	COG4166	transmembrane transport
FFE93_RS09935	COG0037	tRNA processing
FFE93_RS09940	COG3711	transcriptional antiterminator
FFE93_RS09945	COG1263	PTS System
FFE93_RS09945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS09945	COG2190	(PTS) system
FFE93_RS09950	COG2723	6-phospho-beta-galactosidase activity
FFE93_RS09955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_RS09955	COG0674	pyruvate-flavodoxin oxidoreductase activity
FFE93_RS09955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FFE93_RS09955	COG1013	pyruvate-flavodoxin oxidoreductase activity
FFE93_RS09965	COG1285	pathogenesis
FFE93_RS09970	COG3042	response to heat
FFE93_RS09975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFE93_RS09980	COG2911	Protein conserved in bacteria
FFE93_RS09990	COG3784	Protein of unknown function (DUF1318)
FFE93_RS10010	COG0477	Major facilitator Superfamily
FFE93_RS10015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FFE93_RS10020	COG1643	Atp-dependent helicase
FFE93_RS10040	COG3591	Belongs to the peptidase S1B family
FFE93_RS10045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FFE93_RS10050	COG2205	protein histidine kinase activity
FFE93_RS10055	COG0745	RESPONSE REGULATOR receiver
FFE93_RS10065	COG0531	amino acid
FFE93_RS10075	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FFE93_RS10080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FFE93_RS10085	COG0589	response to stress
FFE93_RS10090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFE93_RS10095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFE93_RS10105	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FFE93_RS10135	COG1011	Hydrolase
FFE93_RS10145	COG0531	amino acid
FFE93_RS10150	COG0076	glutamate decarboxylase activity
FFE93_RS10155	COG3023	N-Acetylmuramoyl-L-alanine amidase
FFE93_RS10175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFE93_RS10195	COG4215	(ABC) transporter
FFE93_RS10205	COG1522	sequence-specific DNA binding
FFE93_RS10215	COG0625	glutathione transferase activity
FFE93_RS10235	COG0640	Transcriptional regulator
FFE93_RS10240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FFE93_RS10255	COG4221	oxidoreductase activity
FFE93_RS10310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FFE93_RS10315	COG1940	carbohydrate kinase activity
FFE93_RS10340	COG0583	DNA-binding transcription factor activity
FFE93_RS10345	COG2814	Major facilitator Superfamily
FFE93_RS10365	COG2814	Major facilitator Superfamily
FFE93_RS10375	COG4644	lycopene metabolic process
FFE93_RS10385	COG0114	fumarate hydratase activity
FFE93_RS10390	COG1482	cell wall glycoprotein biosynthetic process
FFE93_RS10395	COG5339	Protein conserved in bacteria
FFE93_RS10405	COG1609	Transcriptional regulator
FFE93_RS10410	COG1263	PTS System
FFE93_RS10410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS10415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FFE93_RS10425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FFE93_RS10430	COG0385	Bile acid
FFE93_RS10435	COG0673	inositol 2-dehydrogenase activity
FFE93_RS10445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS10450	COG1129	ABC transporter
FFE93_RS10455	COG1879	ABC-type sugar transport system periplasmic component
FFE93_RS10470	COG2274	protein secretion by the type I secretion system
FFE93_RS10480	COG2274	protein secretion by the type I secretion system
FFE93_RS10485	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FFE93_RS10495	COG4657	Part of a membrane complex involved in electron transport
FFE93_RS10505	COG4656	Part of a membrane complex involved in electron transport
FFE93_RS10510	COG2207	Transcriptional regulator
FFE93_RS10510	COG3708	Transcriptional regulator
FFE93_RS10520	COG4659	FMN binding
FFE93_RS10530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FFE93_RS10535	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FFE93_RS10540	COG1966	Carbon starvation protein
FFE93_RS10545	COG2879	small protein
FFE93_RS10550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FFE93_RS10555	COG1349	DNA-binding transcription factor activity
FFE93_RS10560	COG0235	Class ii aldolase
FFE93_RS10570	COG0023	Translation Initiation Factor
FFE93_RS10575	COG0284	orotidine-5'-phosphate decarboxylase activity
FFE93_RS10590	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FFE93_RS10595	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FFE93_RS10600	COG0671	phosphoesterase, PA-phosphatase related
FFE93_RS10610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FFE93_RS10625	COG0583	DNA-binding transcription factor activity
FFE93_RS10645	COG0616	signal peptide processing
FFE93_RS10650	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS10665	COG1187	pseudouridine synthase activity
FFE93_RS10680	COG0009	L-threonylcarbamoyladenylate synthase
FFE93_RS10685	COG0613	PHP domain protein
FFE93_RS10700	COG0512	Glutamine amidotransferase of anthranilate synthase
FFE93_RS10710	COG0134	indole-3-glycerol-phosphate synthase activity
FFE93_RS10710	COG0135	phosphoribosylanthranilate isomerase activity
FFE93_RS10715	COG0133	tryptophan synthase activity
FFE93_RS10730	COG3047	cAMP biosynthetic process
FFE93_RS10750	COG2917	probably involved in intracellular septation
FFE93_RS10760	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FFE93_RS10765	COG2350	Protein conserved in bacteria
FFE93_RS10780	COG2200	EAL domain
FFE93_RS10790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFE93_RS10805	COG0444	Belongs to the ABC transporter superfamily
FFE93_RS10810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_RS10830	COG2095	MarC family integral membrane protein
FFE93_RS10840	COG1012	belongs to the aldehyde dehydrogenase family
FFE93_RS10840	COG1454	alcohol dehydrogenase
FFE93_RS10855	COG2916	Histone family protein nucleoid-structuring protein H-NS
FFE93_RS10865	COG0745	RESPONSE REGULATOR receiver
FFE93_RS10870	COG1752	Esterase of the alpha-beta hydrolase superfamily
FFE93_RS10880	COG3012	SEC-C Motif Domain Protein
FFE93_RS10885	COG0788	formyltetrahydrofolate deformylase activity
FFE93_RS10925	COG0583	DNA-binding transcription factor activity
FFE93_RS10930	COG0708	Exodeoxyribonuclease III
FFE93_RS10935	COG0494	nUDIX hydrolase
FFE93_RS10945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFE93_RS10960	COG0778	Nitroreductase
FFE93_RS10965	COG0616	signal peptide processing
FFE93_RS10970	COG0252	asparaginase activity
FFE93_RS10975	COG1335	isochorismatase
FFE93_RS10980	COG3139	Protein of unknown function (DUF1315)
FFE93_RS11005	COG3713	MltA-interacting MipA family protein
FFE93_RS11015	COG2766	serine protein kinase
FFE93_RS11020	COG2718	Belongs to the UPF0229 family
FFE93_RS11030	COG0583	DNA-binding transcription factor activity
FFE93_RS11040	COG2199	diguanylate cyclase activity
FFE93_RS11040	COG2202	Pas domain
FFE93_RS11040	COG2200	EAL domain
FFE93_RS11045	COG2814	Major facilitator Superfamily
FFE93_RS11050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS11060	COG1538	Outer membrane efflux protein
FFE93_RS11065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFE93_RS11075	COG2719	SpoVR family
FFE93_RS11145	COG2314	TM2 domain
FFE93_RS11150	COG0776	regulation of translation
FFE93_RS11170	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FFE93_RS11175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FFE93_RS11185	COG4249	Peptidase C14 caspase catalytic subunit p20
FFE93_RS11190	COG1811	Na channel or pump
FFE93_RS11225	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFE93_RS11230	COG1121	(ABC) transporter
FFE93_RS11235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE93_RS11240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE93_RS11245	COG3001	Fructosamine kinase
FFE93_RS11260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE93_RS11265	COG1917	Cupin 2, conserved barrel domain protein
FFE93_RS11270	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS11280	COG1175	transmembrane transport
FFE93_RS11285	COG0395	ABC-type sugar transport system, permease component
FFE93_RS11290	COG3842	ATPase activity
FFE93_RS11300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FFE93_RS11305	COG1988	membrane-bound metal-dependent
FFE93_RS11310	COG1823	symporter activity
FFE93_RS11315	COG3023	N-Acetylmuramoyl-L-alanine amidase
FFE93_RS11325	COG0823	Involved in the tonB-independent uptake of proteins
FFE93_RS11330	COG2814	Major facilitator Superfamily
FFE93_RS11335	COG0501	Belongs to the peptidase M48B family
FFE93_RS11340	COG0793	Belongs to the peptidase S41A family
FFE93_RS11350	COG1956	GAF domain-containing protein
FFE93_RS11355	COG2995	paraquat-inducible protein a
FFE93_RS11360	COG3008	intermembrane lipid transfer
FFE93_RS11370	COG2814	Major facilitator Superfamily
FFE93_RS11405	COG3706	GGDEF domain
FFE93_RS11405	COG5001	Diguanylate cyclase
FFE93_RS11405	COG2203	Gaf domain
FFE93_RS11405	COG4251	negative regulation of phosphorylation
FFE93_RS11425	COG0625	glutathione transferase activity
FFE93_RS11445	COG3122	Protein conserved in bacteria
FFE93_RS11500	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FFE93_RS11615	COG3566	protein conserved in bacteria
FFE93_RS11625	COG3567	Phage-associated protein, HI1409 family
FFE93_RS11635	COG3077	Addiction module antitoxin, RelB DinJ family
FFE93_RS11640	COG2026	Addiction module toxin, RelE StbE family
FFE93_RS11660	COG1475	DNA binding
FFE93_RS11670	COG0515	serine threonine protein kinase
FFE93_RS11670	COG2815	serine threonine protein kinase
FFE93_RS11685	COG3772	lysozyme
FFE93_RS11765	COG1396	sequence-specific DNA binding
FFE93_RS11805	COG0582	viral genome integration into host DNA
FFE93_RS11815	COG1276	copper resistance
FFE93_RS11820	COG2372	response to copper ion
FFE93_RS11825	COG1528	Iron-storage protein
FFE93_RS11850	COG1770	oligopeptidase
FFE93_RS11865	COG3141	response to X-ray
FFE93_RS11870	COG0513	Belongs to the DEAD box helicase family
FFE93_RS11875	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FFE93_RS11880	COG3140	Belongs to the UPF0181 family
FFE93_RS11890	COG0494	nUDIX hydrolase
FFE93_RS11895	COG1760	l-serine dehydratase
FFE93_RS11900	COG1253	flavin adenine dinucleotide binding
FFE93_RS11905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS11905	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_RS11910	COG3715	PTS system
FFE93_RS11915	COG3716	PTS system mannose fructose sorbose family IID component
FFE93_RS11920	COG4811	Protein of unknown function (DUF986)
FFE93_RS11925	COG1971	Probably functions as a manganese efflux pump
FFE93_RS11935	COG5002	protein histidine kinase activity
FFE93_RS11935	COG3447	MASE1 domain protein
FFE93_RS11935	COG5001	Diguanylate cyclase
FFE93_RS11945	COG2226	methyltransferase
FFE93_RS11950	COG1496	oxidoreductase activity
FFE93_RS11955	COG3344	reverse transcriptase
FFE93_RS11975	COG1113	amino acid transport
FFE93_RS12010	COG2207	Transcriptional regulator
FFE93_RS12030	COG1132	(ABC) transporter
FFE93_RS12050	COG2203	Gaf domain
FFE93_RS12050	COG4251	negative regulation of phosphorylation
FFE93_RS12050	COG3706	GGDEF domain
FFE93_RS12050	COG5001	Diguanylate cyclase
FFE93_RS12060	COG1733	regulation of RNA biosynthetic process
FFE93_RS12065	COG0702	epimerase
FFE93_RS12070	COG0840	transmembrane signaling receptor activity
FFE93_RS12090	COG4974	Belongs to the 'phage' integrase family
FFE93_RS12165	COG4695	Portal protein
FFE93_RS12355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FFE93_RS12405	COG0741	lytic transglycosylase activity
FFE93_RS12405	COG1196	nuclear chromosome segregation
FFE93_RS12405	COG0739	heme binding
FFE93_RS12505	COG3772	lysozyme
FFE93_RS12555	COG0305	Participates in initiation and elongation during chromosome replication
FFE93_RS12585	COG3344	reverse transcriptase
FFE93_RS12640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFE93_RS12645	COG0322	excinuclease ABC activity
FFE93_RS12650	COG2197	response regulator
FFE93_RS12660	COG3136	membrane protein required for alginate biosynthesis
FFE93_RS12670	COG0840	transmembrane signaling receptor activity
FFE93_RS12705	COG1113	amino acid transport
FFE93_RS12710	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FFE93_RS12725	COG0477	Major facilitator Superfamily
FFE93_RS12745	COG0672	)-iron permease
FFE93_RS12750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE93_RS12755	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FFE93_RS12755	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FFE93_RS12755	COG0506	proline dehydrogenase activity
FFE93_RS12770	COG1126	abc transporter atp-binding protein
FFE93_RS12775	COG0765	amino acid transport
FFE93_RS12780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS12785	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FFE93_RS12795	COG1191	sigma factor activity
FFE93_RS12830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FFE93_RS12840	COG1677	Flagellar hook-basal body complex protein FliE
FFE93_RS12855	COG1317	bacterial-type flagellum organization
FFE93_RS12910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFE93_RS12915	COG1256	bacterial-type flagellum assembly
FFE93_RS12950	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FFE93_RS12955	COG1558	bacterial-type flagellum-dependent cell motility
FFE93_RS12960	COG1815	bacterial-type flagellum-dependent cell motility
FFE93_RS12970	COG2747	anti-sigma28 factor FlgM
FFE93_RS12975	COG3418	PFAM FlgN family protein
FFE93_RS12985	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFE93_RS12990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFE93_RS12995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FFE93_RS13000	COG0745	RESPONSE REGULATOR receiver
FFE93_RS13010	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FFE93_RS13015	COG0840	transmembrane signaling receptor activity
FFE93_RS13020	COG0840	transmembrane signaling receptor activity
FFE93_RS13035	COG0835	chemotaxis
FFE93_RS13040	COG0643	Histidine kinase
FFE93_RS13040	COG2198	Histidine kinase
FFE93_RS13045	COG1360	Flagellar Motor Protein
FFE93_RS13065	COG0589	response to stress
FFE93_RS13075	COG1285	pathogenesis
FFE93_RS13080	COG0840	transmembrane signaling receptor activity
FFE93_RS13095	COG1609	Transcriptional regulator
FFE93_RS13100	COG3250	beta-galactosidase activity
FFE93_RS13105	COG3321	synthase
FFE93_RS13105	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS13105	COG0604	alcohol dehydrogenase
FFE93_RS13135	COG3121	Chaperone
FFE93_RS13150	COG3228	Belongs to the MtfA family
FFE93_RS13170	COG0471	metal ion transport
FFE93_RS13185	COG3051	citrate lyase alpha subunit
FFE93_RS13190	COG2301	Belongs to the HpcH HpaI aldolase family
FFE93_RS13195	COG3052	prosthetic group binding
FFE93_RS13200	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FFE93_RS13205	COG3290	protein histidine kinase activity
FFE93_RS13210	COG4565	transcriptional regulatory protein
FFE93_RS13225	COG2271	Major facilitator Superfamily
FFE93_RS13230	COG1840	ABC-type Fe3 transport system, periplasmic component
FFE93_RS13240	COG3842	ATPase activity
FFE93_RS13255	COG2205	protein histidine kinase activity
FFE93_RS13255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS13265	COG3121	Chaperone
FFE93_RS13280	COG3121	Chaperone
FFE93_RS13285	COG1187	pseudouridine synthase activity
FFE93_RS13295	COG0488	(ABC) transporter
FFE93_RS13300	COG0784	Response regulator, receiver
FFE93_RS13300	COG0835	chemotaxis
FFE93_RS13305	COG0534	Mate efflux family protein
FFE93_RS13310	COG0137	argininosuccinate synthase activity
FFE93_RS13315	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FFE93_RS13325	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FFE93_RS13335	COG1492	cobalamin metabolic process
FFE93_RS13400	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FFE93_RS13410	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FFE93_RS13470	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FFE93_RS13485	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FFE93_RS13495	COG1012	belongs to the aldehyde dehydrogenase family
FFE93_RS13505	COG4656	Part of a membrane complex involved in electron transport
FFE93_RS13525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFE93_RS13530	COG1648	precorrin-2 dehydrogenase activity
FFE93_RS13530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFE93_RS13535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFE93_RS13550	COG1129	ABC transporter
FFE93_RS13555	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS13565	COG2926	Belongs to the UPF0265 family
FFE93_RS13575	COG2925	Exonuclease
FFE93_RS13580	COG0531	amino acid
FFE93_RS13590	COG0371	Dehydrogenase
FFE93_RS13595	COG1129	ABC transporter
FFE93_RS13600	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS13605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE93_RS13615	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FFE93_RS13620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FFE93_RS13625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFE93_RS13630	COG0131	Imidazoleglycerol-phosphate dehydratase
FFE93_RS13630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FFE93_RS13640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FFE93_RS13645	COG0107	imidazoleglycerol-phosphate synthase activity
FFE93_RS13650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FFE93_RS13650	COG0140	phosphoribosyl-ATP diphosphatase activity
FFE93_RS13655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FFE93_RS13660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFE93_RS13665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFE93_RS13675	COG0438	transferase activity, transferring glycosyl groups
FFE93_RS13685	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FFE93_RS13720	COG1253	flavin adenine dinucleotide binding
FFE93_RS13725	COG3069	C4-dicarboxylate transmembrane transporter activity
FFE93_RS13730	COG2982	Protein involved in outer membrane biogenesis
FFE93_RS13740	COG0572	uridine kinase
FFE93_RS13745	COG0489	protein tyrosine kinase activity
FFE93_RS13750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE93_RS13750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE93_RS13765	COG2814	Major facilitator Superfamily
FFE93_RS13770	COG1380	Effector of murein hydrolase LrgA
FFE93_RS13775	COG1346	cytolysis
FFE93_RS13785	COG0281	malic enzyme
FFE93_RS13795	COG2949	membrane
FFE93_RS13805	COG0298	carbon dioxide binding
FFE93_RS13810	COG0375	protein maturation
FFE93_RS13815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_RS13820	COG0651	ATP synthesis coupled electron transport
FFE93_RS13825	COG0650	Formate hydrogenlyase subunit 4
FFE93_RS13830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFE93_RS13835	COG4237	Hydrogenase 4 membrane
FFE93_RS13840	COG0651	ATP synthesis coupled electron transport
FFE93_RS13845	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FFE93_RS13845	COG3261	NADH dehydrogenase
FFE93_RS13850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_RS13855	COG3260	NADH ubiquinone oxidoreductase 20
FFE93_RS13865	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FFE93_RS13870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_RS13875	COG3383	formate dehydrogenase (NAD+) activity
FFE93_RS13880	COG3604	Transcriptional regulator
FFE93_RS13905	COG2311	Membrane
FFE93_RS13910	COG0302	gtp cyclohydrolase
FFE93_RS13915	COG0477	Major facilitator Superfamily
FFE93_RS13920	COG0583	DNA-binding transcription factor activity
FFE93_RS13950	COG1136	(ABC) transporter
FFE93_RS13965	COG0303	'Molybdopterin
FFE93_RS13970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FFE93_RS13975	COG0488	(ABC) transporter
FFE93_RS13995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FFE93_RS14010	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FFE93_RS14030	COG0783	Belongs to the Dps family
FFE93_RS14035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FFE93_RS14040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS14045	COG0765	amino acid transport
FFE93_RS14050	COG1126	abc transporter atp-binding protein
FFE93_RS14055	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FFE93_RS14070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FFE93_RS14075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FFE93_RS14095	COG0697	spore germination
FFE93_RS14105	COG1982	Orn Lys Arg decarboxylase major
FFE93_RS14110	COG0531	amino acid
FFE93_RS14115	COG1174	glycine betaine transport
FFE93_RS14120	COG1125	glycine betaine transport
FFE93_RS14125	COG1174	glycine betaine transport
FFE93_RS14130	COG1732	Glycine betaine
FFE93_RS14135	COG2723	6-phospho-beta-galactosidase activity
FFE93_RS14140	COG1263	PTS System
FFE93_RS14140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS14140	COG2190	(PTS) system
FFE93_RS14145	COG1737	Transcriptional regulator
FFE93_RS14180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FFE93_RS14195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FFE93_RS14205	COG2223	nitrite transmembrane transporter activity
FFE93_RS14210	COG0642	Histidine kinase
FFE93_RS14210	COG2198	Histidine kinase
FFE93_RS14220	COG2205	protein histidine kinase activity
FFE93_RS14220	COG0784	Response regulator, receiver
FFE93_RS14230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFE93_RS14235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE93_RS14245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE93_RS14250	COG4574	serine-type endopeptidase inhibitor activity
FFE93_RS14280	COG0814	amino acid
FFE93_RS14300	COG1441	menaquinone biosynthetic process
FFE93_RS14305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FFE93_RS14315	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FFE93_RS14320	COG1169	isochorismate synthase
FFE93_RS14335	COG4575	ribosome binding
FFE93_RS14340	COG0129	dihydroxy-acid dehydratase activity
FFE93_RS14355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFE93_RS14360	COG1609	Transcriptional regulator
FFE93_RS14365	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS14370	COG3265	gluconokinase activity
FFE93_RS14385	COG1007	ATP synthesis coupled electron transport
FFE93_RS14390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_RS14395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFE93_RS14400	COG0713	ATP synthesis coupled electron transport
FFE93_RS14405	COG0839	Belongs to the complex I subunit 6 family
FFE93_RS14410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_RS14415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FFE93_RS14420	COG1034	ATP synthesis coupled electron transport
FFE93_RS14425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FFE93_RS14435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_RS14435	COG0649	NAD binding
FFE93_RS14440	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_RS14445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_RS14450	COG0583	DNA-binding transcription factor activity
FFE93_RS14455	COG0436	Aminotransferase
FFE93_RS14460	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FFE93_RS14470	COG0471	metal ion transport
FFE93_RS14470	COG0490	domain, Protein
FFE93_RS14480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE93_RS14485	COG3013	Belongs to the UPF0304 family
FFE93_RS14490	COG3092	negative regulation of chromosome organization
FFE93_RS14500	COG0280	phosphate acetyltransferase
FFE93_RS14500	COG0857	belongs to the CobB CobQ family
FFE93_RS14505	COG1609	Transcriptional regulator
FFE93_RS14520	COG3037	sugar-specific permease SgaT UlaA
FFE93_RS14530	COG4149	molybdate abc transporter
FFE93_RS14535	COG0725	ABC transporter, periplasmic molybdate-binding protein
FFE93_RS14545	COG3585	molybdate ion transport
FFE93_RS14545	COG2005	Transcriptional regulator
FFE93_RS14550	COG1119	ATPase activity
FFE93_RS14560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FFE93_RS14565	COG1085	galactose-1-phosphate uridylyltransferase
FFE93_RS14570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FFE93_RS14575	COG2017	converts alpha-aldose to the beta-anomer
FFE93_RS14585	COG0588	phosphoglycerate mutase activity
FFE93_RS14590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FFE93_RS14595	COG1230	cation diffusion facilitator family transporter
FFE93_RS14605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FFE93_RS14635	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FFE93_RS14640	COG2885	chlorophyll binding
FFE93_RS14645	COG0823	Involved in the tonB-independent uptake of proteins
FFE93_RS14650	COG3064	Membrane
FFE93_RS14650	COG3064	Membrane
FFE93_RS14655	COG0848	biopolymer transport protein
FFE93_RS14660	COG0811	peptide transport
FFE93_RS14665	COG0824	Thioesterase
FFE93_RS14670	COG3790	cyd operon protein YbgE
FFE93_RS14675	COG4890	Cyd operon protein YbgT
FFE93_RS14680	COG1294	oxidase, subunit
FFE93_RS14685	COG1271	oxidase subunit
FFE93_RS14690	COG0737	Belongs to the 5'-nucleotidase family
FFE93_RS14695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FFE93_RS14700	COG0045	succinate-CoA ligase (ADP-forming) activity
FFE93_RS14705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFE93_RS14710	COG0567	Dehydrogenase, E1 component
FFE93_RS14715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FFE93_RS14720	COG1053	succinate dehydrogenase
FFE93_RS14725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FFE93_RS14760	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FFE93_RS14765	COG1984	allophanate hydrolase subunit 2
FFE93_RS14770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FFE93_RS14775	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FFE93_RS14780	COG5212	phosphodiesterase
FFE93_RS14785	COG0415	Belongs to the DNA photolyase family
FFE93_RS14790	COG3272	Protein of unknown function (DUF1722)
FFE93_RS14805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FFE93_RS14810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FFE93_RS14815	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FFE93_RS14820	COG2205	protein histidine kinase activity
FFE93_RS14825	COG0745	RESPONSE REGULATOR receiver
FFE93_RS14845	COG0033	Phosphoglucomutase
FFE93_RS14850	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FFE93_RS14855	COG0596	Alpha beta hydrolase
FFE93_RS14865	COG0840	transmembrane signaling receptor activity
FFE93_RS14875	COG0735	belongs to the Fur family
FFE93_RS14895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFE93_RS14900	COG2190	(PTS) system
FFE93_RS14900	COG1263	PTS System
FFE93_RS14900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_RS14910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FFE93_RS14915	COG1940	carbohydrate kinase activity
FFE93_RS14915	COG1846	Transcriptional regulator
FFE93_RS14920	COG0647	UMP catabolic process
FFE93_RS14925	COG0367	asparagine synthase
FFE93_RS14960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFE93_RS14965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFE93_RS14970	COG1702	phosphate starvation-inducible protein PhoH
FFE93_RS14975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFE93_RS14980	COG4535	Mg2 and Co2 transporter CorC
FFE93_RS14985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FFE93_RS15005	COG0765	amino acid transport
FFE93_RS15010	COG0765	amino acid transport
FFE93_RS15015	COG1126	abc transporter atp-binding protein
FFE93_RS15020	COG2888	peptidyl-tyrosine sulfation
FFE93_RS15025	COG0495	leucyl-tRNA aminoacylation
FFE93_RS15030	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FFE93_RS15035	COG1466	dna polymerase III delta subunit
FFE93_RS15040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FFE93_RS15045	COG0799	negative regulation of ribosome biogenesis
FFE93_RS15055	COG0768	penicillin binding
FFE93_RS15060	COG0772	Belongs to the SEDS family
FFE93_RS15065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFE93_RS15070	COG1686	Belongs to the peptidase S11 family
FFE93_RS15075	COG2921	Belongs to the UPF0250 family
FFE93_RS15080	COG0321	lipoyl(octanoyl) transferase activity
FFE93_RS15085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FFE93_RS15090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE93_RS15095	COG3706	GGDEF domain
FFE93_RS15110	COG1278	Cold shock
FFE93_RS15115	COG2197	response regulator
FFE93_RS15125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FFE93_RS15140	COG5265	(ABC) transporter
FFE93_RS15145	COG2850	peptidyl-arginine hydroxylation
FFE93_RS15150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE93_RS15180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FFE93_RS15235	COG4386	tail sheath protein
FFE93_RS15400	COG0582	viral genome integration into host DNA
FFE93_RS15410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFE93_RS15415	COG2501	S4 domain
FFE93_RS15420	COG0215	cysteine-tRNA ligase activity
FFE93_RS15425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FFE93_RS15430	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFE93_RS15435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FFE93_RS15440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FFE93_RS15445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FFE93_RS15450	COG4181	ATPase activity
FFE93_RS15455	COG2755	lipolytic protein G-D-S-L family
FFE93_RS15460	COG0300	oxidoreductase activity
FFE93_RS15465	COG3118	belongs to the thioredoxin family
FFE93_RS15470	COG0330	HflC and HflK could
FFE93_RS15475	COG1585	Membrane protein implicated in regulation of membrane protease activity
FFE93_RS15480	COG0789	Transcriptional regulator
FFE93_RS15485	COG2217	Heavy metal translocating P-type atpase
FFE93_RS15490	COG3735	TraB family
FFE93_RS15495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FFE93_RS15515	COG0737	Belongs to the 5'-nucleotidase family
FFE93_RS15520	COG2223	nitrite transmembrane transporter activity
FFE93_RS15525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FFE93_RS15525	COG4651	solute:proton antiporter activity
FFE93_RS15530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE93_RS15535	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FFE93_RS15550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE93_RS15590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FFE93_RS15595	COG0563	adenylate kinase activity
FFE93_RS15600	COG0326	Molecular chaperone. Has ATPase activity
FFE93_RS15605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FFE93_RS15620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFE93_RS15625	COG2832	Protein of unknown function (DUF454)
FFE93_RS15640	COG3264	Mechanosensitive ion channel
FFE93_RS15640	COG1196	nuclear chromosome segregation
FFE93_RS15645	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FFE93_RS15650	COG1309	transcriptional regulator
FFE93_RS15655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS15660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_RS15670	COG3457	Alanine racemase
FFE93_RS15675	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FFE93_RS15680	COG0254	rRNA binding
FFE93_RS15685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FFE93_RS15690	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFE93_RS15695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE93_RS15700	COG1121	(ABC) transporter
FFE93_RS15725	COG3695	enzyme binding
FFE93_RS15730	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FFE93_RS15735	COG1946	Acyl-CoA thioesterase
FFE93_RS15740	COG0004	ammonium transporteR
FFE93_RS15745	COG0347	Belongs to the P(II) protein family
FFE93_RS15750	COG1132	(ABC) transporter
FFE93_RS15755	COG1132	(ABC) transporter
FFE93_RS15760	COG1522	sequence-specific DNA binding
FFE93_RS15770	COG0561	phosphatase activity
FFE93_RS15775	COG4533	DNA binding
FFE93_RS15780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FFE93_RS15785	COG0824	Thioesterase
FFE93_RS15790	COG1555	photosystem II stabilization
FFE93_RS15795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFE93_RS15800	COG0776	regulation of translation
FFE93_RS15805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FFE93_RS15810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FFE93_RS15815	COG0740	serine-type endopeptidase activity
FFE93_RS15820	COG0544	peptidyl-prolyl cis-trans isomerase activity
FFE93_RS15830	COG0271	Belongs to the BolA IbaG family
FFE93_RS15835	COG3056	Lipoprotein
FFE93_RS15840	COG2223	nitrite transmembrane transporter activity
FFE93_RS15850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FFE93_RS15855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFE93_RS15860	COG1845	cytochrome c oxidase, subunit III
FFE93_RS15865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FFE93_RS15870	COG0109	protoheme IX farnesyltransferase activity
FFE93_RS15875	COG2814	Major facilitator Superfamily
FFE93_RS15880	COG1666	GTP binding
FFE93_RS15885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FFE93_RS15890	COG0693	protein deglycase activity
FFE93_RS15895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFE93_RS15895	COG0301	tRNA thio-modification
FFE93_RS15900	COG1722	exodeoxyribonuclease VII activity
FFE93_RS15905	COG0142	geranyltranstransferase activity
FFE93_RS15910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FFE93_RS15915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FFE93_RS15920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FFE93_RS15930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FFE93_RS15935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFE93_RS15935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFE93_RS15940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FFE93_RS15950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFE93_RS15955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFE93_RS15960	COG1862	Preprotein translocase
FFE93_RS15965	COG0343	queuine tRNA-ribosyltransferase activity
FFE93_RS15970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FFE93_RS15970	COG0546	phosphoglycolate phosphatase activity
FFE93_RS16265	COG0582	viral genome integration into host DNA
FFE93_RS16275	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FFE93_RS16280	COG0450	alkyl hydroperoxide reductase
FFE93_RS16300	COG0366	Alpha amylase catalytic
FFE93_RS16320	COG5002	protein histidine kinase activity
FFE93_RS16325	COG0745	RESPONSE REGULATOR receiver
FFE93_RS16330	COG0420	3'-5' exonuclease activity
FFE93_RS16335	COG0419	ATPase involved in DNA repair
FFE93_RS16340	COG1940	carbohydrate kinase activity
FFE93_RS16345	COG2974	May be involved in recombination
FFE93_RS16350	COG3123	guanosine phosphorylase activity
FFE93_RS16355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFE93_RS16400	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FFE93_RS16405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FFE93_RS16415	COG1073	alpha beta
FFE93_RS16425	COG2195	Cleaves the N-terminal amino acid of tripeptides
FFE93_RS16430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FFE93_RS16440	COG2991	Protein conserved in bacteria
FFE93_RS16445	COG1477	protein flavinylation
FFE93_RS16450	COG2871	sodium ion transport
FFE93_RS16455	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FFE93_RS16460	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FFE93_RS16465	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FFE93_RS16470	COG1805	sodium ion transport
FFE93_RS16480	COG3034	peptidoglycan biosynthetic process
FFE93_RS16485	COG0121	glutamine amidotransferase
FFE93_RS16495	COG1960	acyl-CoA dehydrogenase activity
FFE93_RS16500	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
FFE93_RS16510	COG2831	hemolysin activation secretion protein
FFE93_RS16515	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FFE93_RS16525	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FFE93_RS16535	COG0235	Class ii aldolase
FFE93_RS16540	COG0436	Aminotransferase
FFE93_RS16550	COG2814	Major facilitator Superfamily
FFE93_RS16555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FFE93_RS16565	COG1846	Transcriptional regulator
FFE93_RS16570	COG1566	PFAM secretion protein HlyD family protein
FFE93_RS16575	COG2814	Major facilitator Superfamily
FFE93_RS16580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFE93_RS16585	COG3118	belongs to the thioredoxin family
FFE93_RS16590	COG3148	PFAM DTW domain containing protein
FFE93_RS16595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE93_RS16595	COG1042	CoA-binding domain protein
FFE93_RS16595	COG0045	succinate-CoA ligase (ADP-forming) activity
FFE93_RS16600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFE93_RS16640	COG0542	response to heat
FFE93_RS16650	COG0564	pseudouridine synthase activity
FFE93_RS16660	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFE93_RS16665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FFE93_RS16670	COG0077	Prephenate dehydratase
FFE93_RS16670	COG1605	Chorismate mutase
FFE93_RS16675	COG1605	Chorismate mutase
FFE93_RS16675	COG0287	Prephenate dehydrogenase
FFE93_RS16680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FFE93_RS16685	COG3279	Response regulator of the LytR AlgR family
FFE93_RS16690	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FFE93_RS16695	COG3137	Salt-induced outer membrane protein
FFE93_RS16700	COG0335	large ribosomal subunit rRNA binding
FFE93_RS16710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FFE93_RS16720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FFE93_RS16725	COG4137	Cytochrome C assembly protein
FFE93_RS16730	COG4536	flavin adenine dinucleotide binding
FFE93_RS16735	COG1854	S-ribosylhomocysteine lyase activity
FFE93_RS16740	COG2918	glutathione biosynthetic process
FFE93_RS16745	COG1238	metal cluster binding
FFE93_RS16750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE93_RS16785	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FFE93_RS16790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FFE93_RS16795	COG2137	regulation of response to DNA damage stimulus
FFE93_RS16800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FFE93_RS16825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE93_RS16830	COG3958	Transketolase
FFE93_RS16835	COG3959	Transketolase, thiamine diphosphate binding domain
FFE93_RS16840	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS16845	COG1129	ABC transporter
FFE93_RS16855	COG1879	ABC-type sugar transport system periplasmic component
FFE93_RS16870	COG3381	protein complex oligomerization
FFE93_RS16875	COG3302	dmso reductase anchor subunit
FFE93_RS16880	COG0437	4 iron, 4 sulfur cluster binding
FFE93_RS16885	COG0243	molybdopterin cofactor binding
FFE93_RS16890	COG1454	alcohol dehydrogenase
FFE93_RS16895	COG0235	Class ii aldolase
FFE93_RS16900	COG0738	Major facilitator superfamily
FFE93_RS16910	COG1070	Carbohydrate kinase
FFE93_RS16920	COG1349	DNA-binding transcription factor activity
FFE93_RS16925	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FFE93_RS16925	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FFE93_RS16930	COG0640	Transcriptional regulator
FFE93_RS16935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFE93_RS16950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFE93_RS16955	COG1126	abc transporter atp-binding protein
FFE93_RS16965	COG0765	amino acid transport
FFE93_RS16970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS16980	COG0444	Belongs to the ABC transporter superfamily
FFE93_RS16985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_RS16990	COG0601	transmembrane transport
FFE93_RS16995	COG0747	negative chemotaxis
FFE93_RS17000	COG4948	Mandelate Racemase Muconate Lactonizing
FFE93_RS17005	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS17025	COG1538	Outer membrane efflux protein
FFE93_RS17030	COG0577	efflux transmembrane transporter activity
FFE93_RS17030	COG1136	(ABC) transporter
FFE93_RS17035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS17070	COG3539	Fimbrial protein
FFE93_RS17080	COG3121	Chaperone
FFE93_RS17085	COG3188	usher protein
FFE93_RS17110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FFE93_RS17115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFE93_RS17120	COG1388	LysM domain
FFE93_RS17120	COG4942	peptidase
FFE93_RS17125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FFE93_RS17130	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FFE93_RS17135	COG0585	pseudouridine synthase activity
FFE93_RS17140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FFE93_RS17150	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FFE93_RS17155	COG2390	Transcriptional regulator
FFE93_RS17160	COG1461	Dihydroxyacetone kinase
FFE93_RS17165	COG2376	Dihydroxyacetone kinase
FFE93_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_RS17175	COG2814	Major facilitator Superfamily
FFE93_RS17180	COG1063	alcohol dehydrogenase
FFE93_RS17185	COG0698	ribose 5-phosphate isomerase
FFE93_RS17195	COG0529	Catalyzes the synthesis of activated sulfate
FFE93_RS17200	COG2895	sulfate adenylyltransferase (ATP) activity
FFE93_RS17205	COG0175	sulfate reduction
FFE93_RS17210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFE93_RS17210	COG1648	precorrin-2 dehydrogenase activity
FFE93_RS17215	COG2234	aminopeptidase activity
FFE93_RS17220	COG0175	sulfate reduction
FFE93_RS17225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFE93_RS17230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FFE93_RS17235	COG0720	synthase
FFE93_RS17240	COG0602	queuosine metabolic process
FFE93_RS17255	COG0148	phosphopyruvate hydratase activity
FFE93_RS17260	COG0504	CTP synthase activity
FFE93_RS17265	COG3956	TIGRFAM MazG family protein
FFE93_RS17270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FFE93_RS17275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFE93_RS17285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE93_RS17290	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FFE93_RS17295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFE93_RS17305	COG2860	membrane
FFE93_RS17315	COG0316	Belongs to the HesB IscA family
FFE93_RS17325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFE93_RS17335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE93_RS17340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFE93_RS17345	COG1120	ATPase activity
FFE93_RS17350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFE93_RS17355	COG1643	Atp-dependent helicase
FFE93_RS17360	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FFE93_RS17365	COG1489	DNA binding
FFE93_RS17375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFE93_RS17380	COG0617	tRNA 3'-terminal CCA addition
FFE93_RS17385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FFE93_RS17390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FFE93_RS17395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FFE93_RS17400	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FFE93_RS17405	COG0726	polysaccharide deacetylase
FFE93_RS17410	COG0842	Transport permease protein
FFE93_RS17415	COG1131	(ABC) transporter
FFE93_RS17420	COG0288	reversible hydration of carbon dioxide
FFE93_RS17425	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FFE93_RS17430	COG2132	Multicopper oxidase
FFE93_RS17440	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FFE93_RS17505	COG3112	Uncharacterised protein family (UPF0231)
FFE93_RS17520	COG2207	Transcriptional regulator
FFE93_RS17525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE93_RS17530	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFE93_RS17535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FFE93_RS17545	COG2186	Transcriptional regulator
FFE93_RS17550	COG1113	amino acid transport
FFE93_RS17555	COG3725	Membrane protein required for beta-lactamase induction
FFE93_RS17560	COG3023	N-Acetylmuramoyl-L-alanine amidase
FFE93_RS17570	COG4969	Belongs to the N-Me-Phe pilin family
FFE93_RS17575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FFE93_RS17580	COG1459	type II secretion system
FFE93_RS17585	COG0516	GMP reductase activity
FFE93_RS17605	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FFE93_RS17610	COG0494	nUDIX hydrolase
FFE93_RS17635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFE93_RS17640	COG0849	cell division
FFE93_RS17645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FFE93_RS17655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FFE93_RS17660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFE93_RS17665	COG0772	Belongs to the SEDS family
FFE93_RS17675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFE93_RS17680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FFE93_RS17685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FFE93_RS17690	COG0768	penicillin binding
FFE93_RS17695	COG3116	cell division
FFE93_RS17700	COG0275	rRNA processing
FFE93_RS17725	COG0028	Belongs to the TPP enzyme family
FFE93_RS17730	COG1022	Amp-dependent synthetase and ligase
FFE93_RS17750	COG0473	3-isopropylmalate dehydrogenase activity
FFE93_RS17755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FFE93_RS17765	COG2814	Major facilitator Superfamily
FFE93_RS17770	COG1882	Formate acetyltransferase
FFE93_RS17775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FFE93_RS17780	COG4533	DNA binding
FFE93_RS17785	COG4143	(ABC) transporter
FFE93_RS17795	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FFE93_RS17800	COG0586	Pfam SNARE associated Golgi protein
FFE93_RS17805	COG0417	DNA replication proofreading
FFE93_RS17815	COG0564	pseudouridine synthase activity
FFE93_RS17825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FFE93_RS17830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FFE93_RS17845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FFE93_RS17850	COG2967	ApaG domain
FFE93_RS17855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FFE93_RS17860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FFE93_RS17870	COG2966	Psort location CytoplasmicMembrane, score
FFE93_RS17875	COG1280	lysine exporter protein (LysE YggA)
FFE93_RS17880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FFE93_RS17890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FFE93_RS17895	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FFE93_RS17900	COG1047	Peptidyl-prolyl cis-trans
FFE93_RS17905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FFE93_RS17910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FFE93_RS17915	COG0196	riboflavin kinase activity
FFE93_RS17935	COG0583	DNA-binding transcription factor activity
FFE93_RS17940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFE93_RS17945	COG0484	heat shock protein binding
FFE93_RS17955	COG1584	GPR1 FUN34 yaaH family protein
FFE93_RS17965	COG0477	Major facilitator Superfamily
FFE93_RS17970	COG0521	Mo-molybdopterin cofactor biosynthetic process
FFE93_RS17975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FFE93_RS17985	COG3022	response to hydroperoxide
FFE93_RS17995	COG0083	homoserine kinase activity
FFE93_RS18010	COG0745	RESPONSE REGULATOR receiver
FFE93_RS18015	COG3045	CreA protein
FFE93_RS18020	COG3708	Transcriptional regulator
FFE93_RS18020	COG2207	Transcriptional regulator
FFE93_RS18030	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FFE93_RS18035	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FFE93_RS18040	COG0741	lytic transglycosylase activity
FFE93_RS18045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FFE93_RS18055	COG2199	diguanylate cyclase activity
FFE93_RS18060	COG2885	chlorophyll binding
FFE93_RS18065	COG0488	(ABC) transporter
FFE93_RS18075	COG0583	DNA-binding transcription factor activity
FFE93_RS18080	COG0604	alcohol dehydrogenase
FFE93_RS18095	COG0560	Phosphoserine phosphatase
FFE93_RS18100	COG3726	membrane protein affecting hemolysin expression
FFE93_RS18105	COG3550	peptidyl-serine autophosphorylation
FFE93_RS18115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FFE93_RS18120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FFE93_RS18130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE93_RS18135	COG0084	hydrolase, TatD family'
FFE93_RS18140	COG4667	esterase of the alpha-beta hydrolase superfamily
FFE93_RS18150	COG2823	Periplasmic or secreted lipoprotein
FFE93_RS18155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FFE93_RS18165	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FFE93_RS18185	COG0667	Aldo Keto reductase
FFE93_RS18250	COG3284	Transcriptional regulator
FFE93_RS18275	COG2192	nodulation
FFE93_RS18285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_RS18285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFE93_RS18285	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FFE93_RS18290	COG1461	Dihydroxyacetone kinase
FFE93_RS18295	COG2376	Dihydroxyacetone kinase
FFE93_RS18305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_RS18310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_RS18320	COG2235	arginine
FFE93_RS18335	COG0859	PFAM glycosyl transferase family 9
FFE93_RS18340	COG1070	Carbohydrate kinase
FFE93_RS18345	COG2390	Transcriptional regulator
FFE93_RS18355	COG1129	ABC transporter
FFE93_RS18360	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS18365	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS18370	COG1879	ABC-type sugar transport system periplasmic component
FFE93_RS18375	COG1830	Aldolase
FFE93_RS18410	COG1401	restriction endodeoxyribonuclease activity
FFE93_RS18520	COG4619	ABC transporter
FFE93_RS18540	COG0582	viral genome integration into host DNA
FFE93_RS18550	COG0795	lipopolysaccharide-transporting ATPase activity
FFE93_RS18555	COG0795	lipopolysaccharide-transporting ATPase activity
FFE93_RS18560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FFE93_RS18565	COG2927	DNA polymerase III (CHI subunit)
FFE93_RS18580	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FFE93_RS18590	COG2731	YhcH YjgK YiaL family protein
FFE93_RS18600	COG0601	transmembrane transport
FFE93_RS18605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_RS18610	COG0444	Belongs to the ABC transporter superfamily
FFE93_RS18615	COG4608	Belongs to the ABC transporter superfamily
FFE93_RS18625	COG0602	queuosine metabolic process
FFE93_RS18640	COG2188	Transcriptional regulator
FFE93_RS18645	COG3624	Phosphonate C-P lyase system protein PhnG
FFE93_RS18650	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FFE93_RS18655	COG3626	phosphonate metabolism
FFE93_RS18660	COG3627	carbon phosphorus lyase activity
FFE93_RS18665	COG4107	phosphonate C-P lyase system protein PhnK
FFE93_RS18670	COG4778	phosphonate C-P lyase system protein PhnL
FFE93_RS18675	COG3454	Phosphonate metabolism
FFE93_RS18680	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FFE93_RS18685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FFE93_RS18690	COG0702	epimerase
FFE93_RS18695	COG3787	Belongs to the UPF0306 family
FFE93_RS18705	COG3842	ATPase activity
FFE93_RS18710	COG0395	ABC-type sugar transport system, permease component
FFE93_RS18715	COG1175	transmembrane transport
FFE93_RS18720	COG1653	transport
FFE93_RS18740	COG1982	Orn Lys Arg decarboxylase major
FFE93_RS18745	COG0531	amino acid
FFE93_RS18750	COG2827	Endonuclease containing a URI domain
FFE93_RS18755	COG3153	acetyltransferase
FFE93_RS18760	COG3154	lipid carrier protein
FFE93_RS18765	COG0826	peptidase U32
FFE93_RS18770	COG0826	peptidase U32
FFE93_RS18775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE93_RS18780	COG0513	Belongs to the DEAD box helicase family
FFE93_RS18795	COG1185	polyribonucleotide nucleotidyltransferase activity
FFE93_RS18805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FFE93_RS18810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FFE93_RS18820	COG0195	Participates in both transcription termination and antitermination
FFE93_RS18840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFE93_RS18850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FFE93_RS18860	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FFE93_RS18865	COG1534	Rna-binding protein
FFE93_RS18875	COG2027	D-alanyl-D-alanine carboxypeptidase
FFE93_RS18880	COG0745	RESPONSE REGULATOR receiver
FFE93_RS18885	COG0642	Histidine kinase
FFE93_RS18890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFE93_RS18895	COG0697	spore germination
FFE93_RS18910	COG0142	geranyltranstransferase activity
FFE93_RS18920	COG3423	Transcriptional regulator
FFE93_RS18940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FFE93_RS18945	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FFE93_RS18955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FFE93_RS18960	COG2105	PFAM AIG2 family protein
FFE93_RS18965	COG2911	Protein conserved in bacteria
FFE93_RS18975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFE93_RS18980	COG1253	flavin adenine dinucleotide binding
FFE93_RS18990	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FFE93_RS18995	COG1218	3'(2'),5'-bisphosphate nucleotidase
FFE93_RS19000	COG0737	Belongs to the 5'-nucleotidase family
FFE93_RS19010	COG0545	Peptidyl-prolyl cis-trans isomerase
FFE93_RS19015	COG3061	Opacity-associated protein A
FFE93_RS19030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FFE93_RS19040	COG0360	Binds together with S18 to 16S ribosomal RNA
FFE93_RS19055	COG1073	alpha beta
FFE93_RS19060	COG3650	response to hydrogen peroxide
FFE93_RS19065	COG1960	acyl-CoA dehydrogenase activity
FFE93_RS19070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFE93_RS19075	COG0557	exoribonuclease II activity
FFE93_RS19080	COG1959	2 iron, 2 sulfur cluster binding
FFE93_RS19085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FFE93_RS19090	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FFE93_RS19095	COG0330	HflC and HflK could
FFE93_RS19100	COG0330	HflC and HflK could
FFE93_RS19105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FFE93_RS19125	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE93_RS19130	COG0802	atpase or kinase
FFE93_RS19135	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FFE93_RS19135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FFE93_RS19140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FFE93_RS19165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FFE93_RS19170	COG1162	GTPase activity
FFE93_RS19175	COG0688	phosphatidylethanolamine metabolic process
FFE93_RS19180	COG3264	Mechanosensitive ion channel
FFE93_RS19180	COG1511	domain protein
FFE93_RS19190	COG1053	succinate dehydrogenase
FFE93_RS19195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FFE93_RS19200	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FFE93_RS19205	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FFE93_RS19240	COG0459	protein refolding
FFE93_RS19245	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFE93_RS19260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FFE93_RS19270	COG4232	protein-disulfide reductase activity
FFE93_RS19275	COG0493	'glutamate synthase
FFE93_RS19275	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_RS19280	COG2271	Major facilitator Superfamily
FFE93_RS19285	COG2721	sulfolactate sulfo-lyase activity
FFE93_RS19290	COG3835	regulator
FFE93_RS19295	COG1929	Belongs to the glycerate kinase type-1 family
FFE93_RS19300	COG2084	Dehydrogenase
FFE93_RS19310	COG1309	transcriptional regulator
FFE93_RS19325	COG0489	protein tyrosine kinase activity
FFE93_RS19335	COG1215	transferase activity, transferring glycosyl groups
FFE93_RS19340	COG0457	Tetratricopeptide repeat
FFE93_RS19350	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FFE93_RS19370	COG3720	iron ion transport
FFE93_RS19375	COG4558	Periplasmic binding protein
FFE93_RS19380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE93_RS19385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FFE93_RS19390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE93_RS19400	COG4774	siderophore transport
FFE93_RS19405	COG3264	Mechanosensitive ion channel
FFE93_RS19405	COG1511	domain protein
FFE93_RS19415	COG0612	Peptidase, M16
FFE93_RS19420	COG4178	(ABC) transporter
FFE93_RS19425	COG4771	TonB-dependent receptor
FFE93_RS19430	COG3712	iron ion homeostasis
FFE93_RS19435	COG1191	sigma factor activity
FFE93_RS19445	COG0425	Belongs to the sulfur carrier protein TusA family
FFE93_RS19450	COG2391	methyltransferase activity
FFE93_RS19605	COG0784	Response regulator, receiver
FFE93_RS19605	COG2205	protein histidine kinase activity
FFE93_RS19605	COG5002	protein histidine kinase activity
FFE93_RS19615	COG1301	dicarboxylic acid transport
FFE93_RS19620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFE93_RS19625	COG3162	membrane
FFE93_RS19630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE93_RS19675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FFE93_RS19690	COG1024	Enoyl-CoA hydratase
FFE93_RS19690	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFE93_RS19695	COG0183	Belongs to the thiolase family
FFE93_RS19705	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FFE93_RS19725	COG0805	protein transport
FFE93_RS19730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE93_RS19735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE93_RS19740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FFE93_RS19750	COG2226	methyltransferase
FFE93_RS19755	COG1322	Protein conserved in bacteria
FFE93_RS19760	COG0586	Pfam SNARE associated Golgi protein
FFE93_RS19765	COG1966	Carbon starvation protein
FFE93_RS19780	COG0412	Dienelactone hydrolase
FFE93_RS19790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FFE93_RS19795	COG0583	DNA-binding transcription factor activity
FFE93_RS19800	COG0697	spore germination
FFE93_RS19805	COG0679	Auxin Efflux Carrier
FFE93_RS19810	COG0584	glycerophosphoryl diester phosphodiesterase
FFE93_RS19815	COG3842	ATPase activity
FFE93_RS19820	COG0395	ABC-type sugar transport system, permease component
FFE93_RS19825	COG1175	transmembrane transport
FFE93_RS19830	COG1653	transport
FFE93_RS19870	COG0410	ABC transporter
FFE93_RS19880	COG4177	L-phenylalanine transmembrane transporter activity
FFE93_RS19890	COG0683	leucine binding
FFE93_RS19895	COG0456	acetyltransferase
FFE93_RS19905	COG2177	Part of the ABC transporter FtsEX involved in
FFE93_RS19910	COG2884	Cell division ATP-binding protein ftsE
FFE93_RS19915	COG0552	protein localization to endoplasmic reticulum
FFE93_RS19920	COG0742	ribosomal rna small subunit methyltransferase
FFE93_RS19925	COG3776	membrane
FFE93_RS19940	COG3714	YhhN family
FFE93_RS19950	COG0425	Belongs to the sulfur carrier protein TusA family
FFE93_RS19955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FFE93_RS19965	COG0247	lactate metabolic process
FFE93_RS19975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FFE93_RS19980	COG2271	Major facilitator Superfamily
FFE93_RS19985	COG0584	glycerophosphoryl diester phosphodiesterase
FFE93_RS19990	COG0561	phosphatase activity
FFE93_RS19995	COG2267	carboxylic ester hydrolase activity
FFE93_RS20000	COG1280	lysine exporter protein (LysE YggA)
FFE93_RS20005	COG1280	lysine exporter protein (LysE YggA)
FFE93_RS20010	COG0514	ATP-dependent DNA helicase (RecQ)
FFE93_RS20015	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FFE93_RS20020	COG2050	protein possibly involved in aromatic compounds catabolism
FFE93_RS20040	COG5564	TIM-barrel signal transduction protein
FFE93_RS20045	COG5441	Belongs to the UPF0261 family
FFE93_RS20055	COG0210	DNA helicase
FFE93_RS20060	COG1011	Hydrolase
FFE93_RS20065	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FFE93_RS20070	COG3159	Protein conserved in bacteria
FFE93_RS20075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FFE93_RS20080	COG5567	small periplasmic lipoprotein
FFE93_RS20085	COG1965	Belongs to the frataxin family
FFE93_RS20090	COG3072	Adenylate cyclase
FFE93_RS20095	COG0181	hydroxymethylbilane synthase activity
FFE93_RS20100	COG1587	Uroporphyrinogen-III synthase
FFE93_RS20105	COG2959	enzyme of heme biosynthesis
FFE93_RS20110	COG3071	HemY protein
FFE93_RS20150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE93_RS20155	COG2244	polysaccharide biosynthetic process
FFE93_RS20160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFE93_RS20165	COG0456	acetyltransferase
FFE93_RS20170	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FFE93_RS20175	COG1088	dTDP-glucose 4,6-dehydratase activity
FFE93_RS20180	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FFE93_RS20185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FFE93_RS20190	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FFE93_RS20195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFE93_RS20200	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FFE93_RS20205	COG3118	belongs to the thioredoxin family
FFE93_RS20215	COG0248	Ppx GppA phosphatase
FFE93_RS20230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFE93_RS20240	COG3121	Chaperone
FFE93_RS20255	COG3121	Chaperone
FFE93_RS20315	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FFE93_RS20320	COG0583	DNA-binding transcription factor activity
FFE93_RS20335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFE93_RS20340	COG0129	dihydroxy-acid dehydratase activity
FFE93_RS20345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFE93_RS20350	COG3978	acetolactate synthase activity
FFE93_RS20375	COG3085	chromosome segregation
FFE93_RS20380	COG0583	DNA-binding transcription factor activity
FFE93_RS20385	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS20390	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS20395	COG1129	ABC transporter
FFE93_RS20400	COG1879	ABC-type sugar transport system periplasmic component
FFE93_RS20440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FFE93_RS20450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFE93_RS20460	COG1309	transcriptional regulator
FFE93_RS20465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE93_RS20475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFE93_RS20475	COG0678	peroxiredoxin activity
FFE93_RS20480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE93_RS20515	COG0165	Argininosuccinate lyase
FFE93_RS20535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FFE93_RS20545	COG2814	Major facilitator Superfamily
FFE93_RS20550	COG1494	fructose-1,6-bisphosphatase
FFE93_RS20555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE93_RS20560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FFE93_RS20570	COG3074	FtsZ-dependent cytokinesis
FFE93_RS20575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FFE93_RS20580	COG1575	Belongs to the MenA family. Type 1 subfamily
FFE93_RS20585	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FFE93_RS20590	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FFE93_RS20595	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFE93_RS20600	COG1609	Transcriptional regulator
FFE93_RS20605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FFE93_RS20615	COG0254	rRNA binding
FFE93_RS20620	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FFE93_RS20625	COG0626	cystathionine gamma-synthase activity
FFE93_RS20630	COG0527	aspartate kinase activity
FFE93_RS20630	COG0460	homoserine dehydrogenase
FFE93_RS20640	COG3152	Membrane
FFE93_RS20660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FFE93_RS20665	COG3344	reverse transcriptase
FFE93_RS20675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FFE93_RS20680	COG3678	ATP-independent chaperone mediated protein folding
FFE93_RS20685	COG0745	RESPONSE REGULATOR receiver
FFE93_RS20690	COG2205	protein histidine kinase activity
FFE93_RS20695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFE93_RS20695	COG2169	Transcriptional regulator
FFE93_RS20700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FFE93_RS20710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FFE93_RS20715	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FFE93_RS20720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFE93_RS20725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFE93_RS20730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FFE93_RS20735	COG4942	peptidase
FFE93_RS20740	COG2861	carbohydrate metabolic process
FFE93_RS20750	COG0156	8-amino-7-oxononanoate synthase activity
FFE93_RS20755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE93_RS20760	COG0859	PFAM glycosyl transferase family 9
FFE93_RS20765	COG0859	PFAM glycosyl transferase family 9
FFE93_RS20770	COG1519	Transferase
FFE93_RS20790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFE93_RS20795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FFE93_RS20810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FFE93_RS20815	COG0756	dUTP diphosphatase activity
FFE93_RS20820	COG1309	transcriptional regulator
FFE93_RS20830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FFE93_RS20835	COG2199	diguanylate cyclase activity
FFE93_RS20835	COG2200	EAL domain
FFE93_RS20840	COG4608	Belongs to the ABC transporter superfamily
FFE93_RS20845	COG0444	Belongs to the ABC transporter superfamily
FFE93_RS20850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_RS20855	COG0601	transmembrane transport
FFE93_RS20860	COG0747	negative chemotaxis
FFE93_RS20865	COG3210	domain, Protein
FFE93_RS20870	COG2831	hemolysin activation secretion protein
FFE93_RS20880	COG2271	Major facilitator Superfamily
FFE93_RS20885	COG3851	Histidine kinase
FFE93_RS20890	COG2197	response regulator
FFE93_RS20895	COG2194	sulfuric ester hydrolase activity
FFE93_RS20900	COG1764	response to oxidative stress
FFE93_RS20915	COG2986	histidine ammonia-lyase
FFE93_RS20920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FFE93_RS20925	COG5001	Diguanylate cyclase
FFE93_RS20930	COG1024	Enoyl-CoA hydratase
FFE93_RS20935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE93_RS20945	COG2860	membrane
FFE93_RS20950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FFE93_RS20965	COG1758	RNA polymerase activity
FFE93_RS20970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FFE93_RS20975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFE93_RS20980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FFE93_RS20985	COG0786	glutamate:sodium symporter activity
FFE93_RS20990	COG2233	PERMEase
FFE93_RS20995	COG2982	Protein involved in outer membrane biogenesis
FFE93_RS21030	COG3423	Transcriptional regulator
FFE93_RS21045	COG2204	response regulator
FFE93_RS21050	COG0456	acetyltransferase
FFE93_RS21055	COG1490	D-aminoacyl-tRNA deacylase activity
FFE93_RS21065	COG1011	Hydrolase
FFE93_RS21080	COG3852	Histidine kinase
FFE93_RS21090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFE93_RS21100	COG3078	GTPase activator activity
FFE93_RS21110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FFE93_RS21115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFE93_RS21115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFE93_RS21120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FFE93_RS21125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFE93_RS21130	COG3084	Protein conserved in bacteria
FFE93_RS21140	COG1763	Mo-molybdopterin cofactor biosynthetic process
FFE93_RS21170	COG2186	Transcriptional regulator
FFE93_RS21175	COG0477	Major facilitator Superfamily
FFE93_RS21180	COG1609	Transcriptional regulator
FFE93_RS21185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE93_RS21195	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_RS21200	COG1129	ABC transporter
FFE93_RS21205	COG1869	D-ribose catabolic process
FFE93_RS21210	COG3158	transport of potassium into the cell
FFE93_RS21215	COG0714	Associated with various cellular activities
FFE93_RS21220	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FFE93_RS21230	COG2502	aspartate--ammonia ligase
FFE93_RS21235	COG1522	sequence-specific DNA binding
FFE93_RS21240	COG0716	FMN binding
FFE93_RS21245	COG0445	tRNA wobble uridine modification
FFE93_RS21250	COG0357	Ribosomal RNA small subunit methyltransferase G
FFE93_RS21255	COG3312	ion transport
FFE93_RS21260	COG0356	it plays a direct role in the translocation of protons across the membrane
FFE93_RS21270	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FFE93_RS21275	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFE93_RS21280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FFE93_RS21285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FFE93_RS21290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FFE93_RS21295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FFE93_RS21300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FFE93_RS21310	COG0659	secondary active sulfate transmembrane transporter activity
FFE93_RS21315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FFE93_RS21320	COG0573	inorganic phosphate transmembrane transporter activity
FFE93_RS21325	COG0581	inorganic phosphate transmembrane transporter activity
FFE93_RS21335	COG0704	Plays a role in the regulation of phosphate uptake
FFE93_RS21345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_RS21350	COG0765	amino acid transport
FFE93_RS21355	COG0765	amino acid transport
FFE93_RS21360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE93_RS21365	COG2252	PERMEase
FFE93_RS21375	COG4566	intracellular signal transduction
FFE93_RS21380	COG4191	Histidine kinase
FFE93_RS21385	COG0431	NADPH-dependent FMN reductase
FFE93_RS21390	COG0840	transmembrane signaling receptor activity
FFE93_RS21395	COG2011	ABC-type metal ion transport system permease component
FFE93_RS21400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFE93_RS21410	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FFE93_RS21415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FFE93_RS21420	COG0706	membrane insertase activity
FFE93_RS21430	COG0594	ribonuclease P activity
FFE93_RS21435	COG0230	Belongs to the bacterial ribosomal protein bL34 family