locus-tag	class	description
PBT89_RS00010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBT89_RS00025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBT89_RS00030	COG0594	ribonuclease P activity
PBT89_RS00035	COG0793	Belongs to the peptidase S41A family
PBT89_RS00040	COG2153	protein acetylation
PBT89_RS00045	COG0698	ribose 5-phosphate isomerase
PBT89_RS00050	COG0557	exoribonuclease II activity
PBT89_RS00070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PBT89_RS00075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBT89_RS00095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBT89_RS00105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PBT89_RS00110	COG0445	tRNA wobble uridine modification
PBT89_RS00135	COG0470	DNA polymerase III
PBT89_RS00140	COG0126	phosphoglycerate kinase activity
PBT89_RS00155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBT89_RS00180	COG1215	transferase activity, transferring glycosyl groups
PBT89_RS00190	COG0151	Belongs to the GarS family
PBT89_RS00215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PBT89_RS00260	COG0356	it plays a direct role in the translocation of protons across the membrane
PBT89_RS00265	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBT89_RS00270	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PBT89_RS00275	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBT89_RS00280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PBT89_RS00285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PBT89_RS00300	COG0756	dUTP diphosphatase activity
PBT89_RS00335	COG1607	acyl-coa hydrolase
PBT89_RS00350	COG0180	Tryptophanyl-tRNA synthetase
PBT89_RS00375	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PBT89_RS00380	COG0826	peptidase U32
PBT89_RS00390	COG1054	Belongs to the UPF0176 family
PBT89_RS00395	COG1774	PSP1 C-terminal conserved region
PBT89_RS00405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PBT89_RS00410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PBT89_RS00435	COG0823	Involved in the tonB-independent uptake of proteins
PBT89_RS00435	COG1506	peptidase
PBT89_RS00450	COG1253	flavin adenine dinucleotide binding
PBT89_RS00465	COG0113	porphobilinogen synthase activity
PBT89_RS00470	COG0408	coproporphyrinogen oxidase activity
PBT89_RS00485	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PBT89_RS00495	COG0181	hydroxymethylbilane synthase activity
PBT89_RS00500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PBT89_RS00515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PBT89_RS00530	COG1981	membrane
PBT89_RS00540	COG1024	Enoyl-CoA hydratase
PBT89_RS00545	COG2312	Erythromycin esterase
PBT89_RS00555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PBT89_RS00565	COG1418	mRNA catabolic process
PBT89_RS00580	COG0484	heat shock protein binding
PBT89_RS00595	COG4771	TonB-dependent receptor
PBT89_RS00600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PBT89_RS00600	COG1321	iron dependent repressor
PBT89_RS00630	COG1999	signal sequence binding
PBT89_RS00635	COG0750	zinc metalloprotease
PBT89_RS00640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBT89_RS00645	COG0024	Methionine aminopeptidase
PBT89_RS00650	COG1621	beta-fructofuranosidase activity
PBT89_RS00680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PBT89_RS00685	COG1335	isochorismatase
PBT89_RS00700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PBT89_RS00705	COG1381	Involved in DNA repair and RecF pathway recombination
PBT89_RS00710	COG4206	TonB-dependent receptor
PBT89_RS00720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PBT89_RS00735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PBT89_RS00740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PBT89_RS00750	COG0189	ligase activity
PBT89_RS00760	COG0322	excinuclease ABC activity
PBT89_RS00775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBT89_RS00780	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PBT89_RS00785	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PBT89_RS00795	COG3483	tryptophan 2,3-dioxygenase activity
PBT89_RS00805	COG0166	Belongs to the GPI family
PBT89_RS00810	COG4771	TonB-dependent receptor
PBT89_RS00815	COG4771	TonB-dependent receptor
PBT89_RS00825	COG2356	endonuclease I
PBT89_RS00870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PBT89_RS00885	COG2151	metal-sulfur cluster biosynthetic enzyme
PBT89_RS00890	COG2166	iron-sulfur cluster assembly
PBT89_RS00905	COG0719	Fe-S assembly protein
PBT89_RS00910	COG0396	ATPase activity
PBT89_RS00920	COG0719	Fe-S assembly protein
PBT89_RS00935	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PBT89_RS00950	COG0006	proline dipeptidase activity
PBT89_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS00960	COG0367	asparagine synthase
PBT89_RS00970	COG1053	succinate dehydrogenase
PBT89_RS00980	COG0436	Aminotransferase
PBT89_RS01000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT89_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS01010	COG2259	Doxx family
PBT89_RS01015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PBT89_RS01040	COG4109	DRTGG domain
PBT89_RS01080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBT89_RS01095	COG0629	single-stranded DNA binding
PBT89_RS01100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT89_RS01115	COG0123	including yeast histone deacetylase and acetoin utilization protein
PBT89_RS01120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT89_RS01120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT89_RS01130	COG0792	nuclease activity
PBT89_RS01135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PBT89_RS01145	COG3590	peptidase
PBT89_RS01160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT89_RS01190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PBT89_RS01215	COG1309	transcriptional regulator
PBT89_RS01225	COG0567	Dehydrogenase, E1 component
PBT89_RS01230	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT89_RS01240	COG0084	hydrolase, TatD family'
PBT89_RS01250	COG0252	asparaginase activity
PBT89_RS01260	COG0811	peptide transport
PBT89_RS01270	COG0848	biopolymer transport protein
PBT89_RS01290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PBT89_RS01295	COG0564	pseudouridine synthase activity
PBT89_RS01305	COG0017	Asparaginyl-tRNA synthetase
PBT89_RS01320	COG0233	cytoplasmic translational termination
PBT89_RS01325	COG0528	UMP kinase activity
PBT89_RS01330	COG2738	Putative neutral zinc metallopeptidase
PBT89_RS01340	COG0708	Exodeoxyribonuclease III
PBT89_RS01345	COG1360	Flagellar Motor Protein
PBT89_RS01350	COG0667	Aldo Keto reductase
PBT89_RS01360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PBT89_RS01375	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PBT89_RS01380	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PBT89_RS01385	COG0297	glycogen (starch) synthase activity
PBT89_RS01395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PBT89_RS01400	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PBT89_RS01405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PBT89_RS01415	COG3655	Transcriptional regulator
PBT89_RS01430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PBT89_RS01430	COG2111	Na H antiporter
PBT89_RS01435	COG2111	Na H antiporter
PBT89_RS01440	COG1006	Multisubunit Na H antiporter MnhC subunit
PBT89_RS01445	COG0651	ATP synthesis coupled electron transport
PBT89_RS01450	COG1863	multisubunit Na H antiporter MnhE subunit
PBT89_RS01455	COG2212	antiporter activity
PBT89_RS01460	COG1320	monovalent cation:proton antiporter activity
PBT89_RS01465	COG0156	8-amino-7-oxononanoate synthase activity
PBT89_RS01470	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PBT89_RS01475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PBT89_RS01480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBT89_RS01485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PBT89_RS01505	COG2137	regulation of response to DNA damage stimulus
PBT89_RS01520	COG0776	regulation of translation
PBT89_RS01530	COG0629	single-stranded DNA binding
PBT89_RS01550	COG0612	Peptidase, M16
PBT89_RS01555	COG0612	Peptidase, M16
PBT89_RS01565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PBT89_RS01570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PBT89_RS01580	COG1629	transport
PBT89_RS01610	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PBT89_RS01620	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PBT89_RS01625	COG0702	epimerase
PBT89_RS01630	COG1733	regulation of RNA biosynthetic process
PBT89_RS01650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PBT89_RS01680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBT89_RS01695	COG2205	protein histidine kinase activity
PBT89_RS01700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PBT89_RS01710	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PBT89_RS01715	COG0519	Catalyzes the synthesis of GMP from XMP
PBT89_RS01730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PBT89_RS01735	COG1968	undecaprenyl-diphosphatase activity
PBT89_RS01745	COG2177	Part of the ABC transporter FtsEX involved in
PBT89_RS01755	COG0495	leucyl-tRNA aminoacylation
PBT89_RS01765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PBT89_RS01770	COG0228	four-way junction DNA binding
PBT89_RS01785	COG3118	belongs to the thioredoxin family
PBT89_RS01800	COG4974	Belongs to the 'phage' integrase family
PBT89_RS01880	COG2205	protein histidine kinase activity
PBT89_RS01885	COG0745	RESPONSE REGULATOR receiver
PBT89_RS01895	COG0629	single-stranded DNA binding
PBT89_RS01900	COG2003	Belongs to the UPF0758 family
PBT89_RS01920	COG3279	Response regulator of the LytR AlgR family
PBT89_RS01935	COG4771	TonB-dependent receptor
PBT89_RS01955	COG3177	Filamentation induced by cAMP protein fic
PBT89_RS01960	COG1595	DNA-templated transcription, initiation
PBT89_RS01970	COG1629	transport
PBT89_RS01990	COG1335	isochorismatase
PBT89_RS01995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PBT89_RS02015	COG1994	Peptidase M50
PBT89_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS02055	COG5002	protein histidine kinase activity
PBT89_RS02060	COG0745	RESPONSE REGULATOR receiver
PBT89_RS02065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PBT89_RS02100	COG0545	Peptidyl-prolyl cis-trans isomerase
PBT89_RS02105	COG1082	Xylose isomerase domain protein TIM barrel
PBT89_RS02120	COG3250	beta-galactosidase activity
PBT89_RS02135	COG0702	epimerase
PBT89_RS02140	COG4771	TonB-dependent receptor
PBT89_RS02145	COG2205	protein histidine kinase activity
PBT89_RS02145	COG3292	Two component regulator propeller
PBT89_RS02145	COG0745	RESPONSE REGULATOR receiver
PBT89_RS02155	COG1629	transport
PBT89_RS02175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT89_RS02185	COG1538	Outer membrane efflux protein
PBT89_RS02220	COG4221	oxidoreductase activity
PBT89_RS02225	COG1607	acyl-coa hydrolase
PBT89_RS02255	COG2072	flavoprotein involved in K transport
PBT89_RS02265	COG1380	Effector of murein hydrolase LrgA
PBT89_RS02270	COG1346	cytolysis
PBT89_RS02280	COG0784	Response regulator, receiver
PBT89_RS02280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PBT89_RS02280	COG2198	Histidine kinase
PBT89_RS02280	COG2205	protein histidine kinase activity
PBT89_RS02330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PBT89_RS02340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PBT89_RS02365	COG2315	Protein conserved in bacteria
PBT89_RS02370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBT89_RS02390	COG0739	heme binding
PBT89_RS02395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PBT89_RS02405	COG0666	response to abiotic stimulus
PBT89_RS02415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PBT89_RS02425	COG0861	Integral membrane protein TerC family
PBT89_RS02430	COG2808	Putative FMN-binding domain
PBT89_RS02435	COG2323	membrane
PBT89_RS02440	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS02445	COG0584	glycerophosphoryl diester phosphodiesterase
PBT89_RS02450	COG2081	HI0933 family
PBT89_RS02475	COG1187	pseudouridine synthase activity
PBT89_RS02480	COG1166	arginine decarboxylase activity
PBT89_RS02485	COG0010	Belongs to the arginase family
PBT89_RS02510	COG1215	transferase activity, transferring glycosyl groups
PBT89_RS02515	COG0463	Glycosyl transferase, family 2
PBT89_RS02535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBT89_RS02545	COG0463	Glycosyl transferase, family 2
PBT89_RS02560	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PBT89_RS02585	COG3279	Response regulator of the LytR AlgR family
PBT89_RS02595	COG3537	Alpha-1,2-mannosidase
PBT89_RS02605	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
PBT89_RS02620	COG3537	Alpha-1,2-mannosidase
PBT89_RS02625	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PBT89_RS02635	COG1629	transport
PBT89_RS02650	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT89_RS02675	COG4771	TonB-dependent receptor
PBT89_RS02685	COG0471	metal ion transport
PBT89_RS02710	COG3142	Participates in the control of copper homeostasis
PBT89_RS02720	COG0459	protein refolding
PBT89_RS02725	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PBT89_RS02750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT89_RS02755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PBT89_RS02755	COG1754	DNA topoisomerase type I activity
PBT89_RS02765	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT89_RS02795	COG0488	(ABC) transporter
PBT89_RS02800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT89_RS02830	COG0668	transmembrane transport
PBT89_RS02850	COG0798	PFAM Bile acid sodium symporter
PBT89_RS02875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PBT89_RS02880	COG1349	DNA-binding transcription factor activity
PBT89_RS02885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PBT89_RS02890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PBT89_RS02895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PBT89_RS02905	COG0386	Belongs to the glutathione peroxidase family
PBT89_RS02910	COG1846	Transcriptional regulator
PBT89_RS02935	COG0659	secondary active sulfate transmembrane transporter activity
PBT89_RS02940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PBT89_RS02950	COG1160	GTP binding
PBT89_RS02980	COG0739	heme binding
PBT89_RS02985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PBT89_RS03000	COG3186	Phenylalanine-4-hydroxylase
PBT89_RS03020	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PBT89_RS03030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PBT89_RS03050	COG0110	maltose O-acetyltransferase activity
PBT89_RS03075	COG1428	Deoxynucleoside kinase
PBT89_RS03085	COG4946	Tricorn protease homolog
PBT89_RS03085	COG1506	peptidase
PBT89_RS03085	COG0823	Involved in the tonB-independent uptake of proteins
PBT89_RS03095	COG2755	lipolytic protein G-D-S-L family
PBT89_RS03095	COG0657	acetylesterase activity
PBT89_RS03100	COG1119	ATPase activity
PBT89_RS03110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBT89_RS03180	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PBT89_RS03240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PBT89_RS03240	COG1519	Transferase
PBT89_RS03250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PBT89_RS03315	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PBT89_RS03330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBT89_RS03340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PBT89_RS03350	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT89_RS03350	COG0022	dehydrogenase e1 component
PBT89_RS03360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PBT89_RS03365	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PBT89_RS03380	COG1595	DNA-templated transcription, initiation
PBT89_RS03390	COG4771	TonB-dependent receptor
PBT89_RS03395	COG0702	epimerase
PBT89_RS03400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT89_RS03405	COG0612	Peptidase, M16
PBT89_RS03415	COG1428	Deoxynucleoside kinase
PBT89_RS03430	COG0471	metal ion transport
PBT89_RS03430	COG3273	potassium ion transport
PBT89_RS03445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PBT89_RS03455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBT89_RS03460	COG1960	acyl-CoA dehydrogenase activity
PBT89_RS03470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PBT89_RS03490	COG1959	2 iron, 2 sulfur cluster binding
PBT89_RS03500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBT89_RS03510	COG1648	precorrin-2 dehydrogenase activity
PBT89_RS03510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PBT89_RS03515	COG0492	ferredoxin-NADP+ reductase activity
PBT89_RS03520	COG1765	OsmC-like protein
PBT89_RS03525	COG0646	methionine synthase
PBT89_RS03525	COG1410	methionine synthase
PBT89_RS03535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PBT89_RS03540	COG0460	homoserine dehydrogenase
PBT89_RS03540	COG0527	aspartate kinase activity
PBT89_RS03555	COG1605	Chorismate mutase
PBT89_RS03555	COG0077	Prephenate dehydratase
PBT89_RS03560	COG0436	Aminotransferase
PBT89_RS03565	COG0287	Prephenate dehydrogenase
PBT89_RS03570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PBT89_RS03580	COG1162	GTPase activity
PBT89_RS03585	COG1490	D-aminoacyl-tRNA deacylase activity
PBT89_RS03615	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PBT89_RS03620	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PBT89_RS03655	COG4771	TonB-dependent receptor
PBT89_RS03660	COG0702	epimerase
PBT89_RS03675	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT89_RS03685	COG1610	YqeY-like protein
PBT89_RS03705	COG3119	arylsulfatase activity
PBT89_RS03710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT89_RS03730	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT89_RS03760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBT89_RS03765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT89_RS03770	COG2207	Transcriptional regulator
PBT89_RS03775	COG0778	Nitroreductase
PBT89_RS03780	COG0737	Belongs to the 5'-nucleotidase family
PBT89_RS03785	COG0737	Belongs to the 5'-nucleotidase family
PBT89_RS03790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBT89_RS03815	COG0497	DNA recombination
PBT89_RS03820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PBT89_RS03825	COG0463	Glycosyl transferase, family 2
PBT89_RS03825	COG1216	Glycosyl transferase, family 2
PBT89_RS03835	COG0237	dephospho-CoA kinase activity
PBT89_RS03850	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PBT89_RS03855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PBT89_RS03870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PBT89_RS03880	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBT89_RS03890	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PBT89_RS03915	COG4771	TonB-dependent receptor
PBT89_RS03920	COG0561	phosphatase activity
PBT89_RS03930	COG3345	alpha-galactosidase
PBT89_RS03940	COG2207	Transcriptional regulator
PBT89_RS03955	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
PBT89_RS03960	COG2942	2-epimerase
PBT89_RS03970	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT89_RS03980	COG2205	protein histidine kinase activity
PBT89_RS03980	COG3292	Two component regulator propeller
PBT89_RS03980	COG0745	RESPONSE REGULATOR receiver
PBT89_RS03985	COG4771	TonB-dependent receptor
PBT89_RS03990	COG0702	epimerase
PBT89_RS04000	COG3250	beta-galactosidase activity
PBT89_RS04005	COG1501	Belongs to the glycosyl hydrolase 31 family
PBT89_RS04010	COG1082	Xylose isomerase domain protein TIM barrel
PBT89_RS04015	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT89_RS04025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PBT89_RS04035	COG0745	RESPONSE REGULATOR receiver
PBT89_RS04075	COG2318	DinB family
PBT89_RS04090	COG4771	TonB-dependent receptor
PBT89_RS04095	COG0702	epimerase
PBT89_RS04110	COG0584	glycerophosphoryl diester phosphodiesterase
PBT89_RS04120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBT89_RS04125	COG3850	Histidine kinase
PBT89_RS04125	COG3437	response regulator, receiver
PBT89_RS04125	COG4999	Histidine kinase
PBT89_RS04125	COG2205	protein histidine kinase activity
PBT89_RS04130	COG3781	membrane
PBT89_RS04140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PBT89_RS04145	COG2169	Transcriptional regulator
PBT89_RS04145	COG1917	Cupin 2, conserved barrel domain protein
PBT89_RS04165	COG1595	DNA-templated transcription, initiation
PBT89_RS04180	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT89_RS04180	COG3952	Lipid A Biosynthesis
PBT89_RS04185	COG0463	Glycosyl transferase, family 2
PBT89_RS04190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT89_RS04195	COG1703	isobutyryl-CoA mutase activity
PBT89_RS04200	COG1764	response to oxidative stress
PBT89_RS04235	COG0653	protein targeting
PBT89_RS04245	COG2096	Adenosyltransferase
PBT89_RS04255	COG1136	(ABC) transporter
PBT89_RS04265	COG0488	(ABC) transporter
PBT89_RS04275	COG0489	protein tyrosine kinase activity
PBT89_RS04280	COG2226	methyltransferase
PBT89_RS04305	COG0463	Glycosyl transferase, family 2
PBT89_RS04310	COG1216	Glycosyl transferase, family 2
PBT89_RS04310	COG0463	Glycosyl transferase, family 2
PBT89_RS04320	COG0463	Glycosyl transferase, family 2
PBT89_RS04355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PBT89_RS04360	COG2089	acid synthase
PBT89_RS04370	COG0297	glycogen (starch) synthase activity
PBT89_RS04370	COG0438	transferase activity, transferring glycosyl groups
PBT89_RS04410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PBT89_RS04415	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PBT89_RS04425	COG1137	ATPase activity
PBT89_RS04435	COG0805	protein transport
PBT89_RS04440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PBT89_RS04440	COG0517	IMP dehydrogenase activity
PBT89_RS04445	COG0514	ATP-dependent DNA helicase (RecQ)
PBT89_RS04470	COG3876	Protein conserved in bacteria
PBT89_RS04475	COG0577	efflux transmembrane transporter activity
PBT89_RS04490	COG1115	amino acid carrier protein
PBT89_RS04510	COG1115	amino acid carrier protein
PBT89_RS04520	COG1960	acyl-CoA dehydrogenase activity
PBT89_RS04525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PBT89_RS04530	COG4974	Belongs to the 'phage' integrase family
PBT89_RS04535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PBT89_RS04560	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PBT89_RS04580	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PBT89_RS04585	COG0081	regulation of translation
PBT89_RS04590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PBT89_RS04595	COG0222	ribosome binding
PBT89_RS04600	COG0085	RNA polymerase activity
PBT89_RS04605	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PBT89_RS04615	COG0248	Ppx GppA phosphatase
PBT89_RS04620	COG1115	amino acid carrier protein
PBT89_RS04625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PBT89_RS04630	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PBT89_RS04655	COG0579	oxidoreductase
PBT89_RS04670	COG0561	phosphatase activity
PBT89_RS04710	COG0784	Response regulator, receiver
PBT89_RS04710	COG2198	Histidine kinase
PBT89_RS04710	COG5002	protein histidine kinase activity
PBT89_RS04715	COG0326	Molecular chaperone. Has ATPase activity
PBT89_RS04730	COG1506	peptidase
PBT89_RS04735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBT89_RS04775	COG3852	Histidine kinase
PBT89_RS04790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PBT89_RS04795	COG0308	aminopeptidase N
PBT89_RS04830	COG1473	amidohydrolase
PBT89_RS04845	COG0009	L-threonylcarbamoyladenylate synthase
PBT89_RS04850	COG1360	Flagellar Motor Protein
PBT89_RS04855	COG0463	Glycosyl transferase, family 2
PBT89_RS04870	COG1575	Belongs to the MenA family. Type 1 subfamily
PBT89_RS04875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PBT89_RS04880	COG4948	Mandelate Racemase Muconate Lactonizing
PBT89_RS04885	COG1266	CAAX protease self-immunity
PBT89_RS04910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PBT89_RS04925	COG0488	(ABC) transporter
PBT89_RS04935	COG2197	response regulator
PBT89_RS04940	COG4585	Histidine kinase
PBT89_RS04950	COG0071	Belongs to the small heat shock protein (HSP20) family
PBT89_RS04965	COG0534	Mate efflux family protein
PBT89_RS04975	COG0671	phosphoesterase, PA-phosphatase related
PBT89_RS04980	COG0477	Major facilitator Superfamily
PBT89_RS04980	COG2814	Major facilitator Superfamily
PBT89_RS05005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBT89_RS05005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT89_RS05015	COG2115	Belongs to the xylose isomerase family
PBT89_RS05025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PBT89_RS05030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PBT89_RS05040	COG1312	Catalyzes the dehydration of D-mannonate
PBT89_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS05050	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PBT89_RS05055	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS05060	COG1904	glucuronate isomerase
PBT89_RS05070	COG0800	Aldolase
PBT89_RS05080	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PBT89_RS05090	COG0246	Mannitol dehydrogenase
PBT89_RS05095	COG2721	sulfolactate sulfo-lyase activity
PBT89_RS05100	COG1609	Transcriptional regulator
PBT89_RS05110	COG4771	TonB-dependent receptor
PBT89_RS05125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PBT89_RS05135	COG2755	lipolytic protein G-D-S-L family
PBT89_RS05160	COG2755	lipolytic protein G-D-S-L family
PBT89_RS05200	COG0179	Fumarylacetoacetate (FAA) hydrolase
PBT89_RS05205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBT89_RS05210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT89_RS05225	COG1629	transport
PBT89_RS05230	COG0702	epimerase
PBT89_RS05235	COG1629	transport
PBT89_RS05235	COG4206	TonB-dependent receptor
PBT89_RS05240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PBT89_RS05245	COG3250	beta-galactosidase activity
PBT89_RS05260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT89_RS05270	COG3408	Glycogen debranching enzyme
PBT89_RS05270	COG3119	arylsulfatase activity
PBT89_RS05305	COG0673	inositol 2-dehydrogenase activity
PBT89_RS05325	COG3250	beta-galactosidase activity
PBT89_RS05330	COG3940	Belongs to the glycosyl hydrolase 43 family
PBT89_RS05375	COG4771	TonB-dependent receptor
PBT89_RS05445	COG3408	Glycogen debranching enzyme
PBT89_RS05455	COG3250	beta-galactosidase activity
PBT89_RS05460	COG3250	beta-galactosidase activity
PBT89_RS05465	COG1063	alcohol dehydrogenase
PBT89_RS05470	COG3254	rhamnose metabolic process
PBT89_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS05485	COG0738	Major facilitator superfamily
PBT89_RS05495	COG3347	Dehydrogenase
PBT89_RS05495	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS05500	COG4952	isomerase
PBT89_RS05510	COG1304	FMN binding
PBT89_RS05545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PBT89_RS05560	COG0702	epimerase
PBT89_RS05565	COG3250	beta-galactosidase activity
PBT89_RS05570	COG2207	Transcriptional regulator
PBT89_RS05575	COG4771	TonB-dependent receptor
PBT89_RS05580	COG0702	epimerase
PBT89_RS05585	COG1785	Belongs to the alkaline phosphatase family
PBT89_RS05595	COG0612	Peptidase, M16
PBT89_RS05610	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PBT89_RS05615	COG0076	glutamate decarboxylase activity
PBT89_RS05625	COG0519	Catalyzes the synthesis of GMP from XMP
PBT89_RS05625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PBT89_RS05655	COG0482	sulfurtransferase activity
PBT89_RS05670	COG0706	membrane insertase activity
PBT89_RS05675	COG0504	CTP synthase activity
PBT89_RS05680	COG3530	Putative quorum-sensing-regulated virulence factor
PBT89_RS05735	COG0494	nUDIX hydrolase
PBT89_RS05740	COG0516	GMP reductase activity
PBT89_RS05750	COG0019	diaminopimelate decarboxylase activity
PBT89_RS05755	COG2814	Major facilitator Superfamily
PBT89_RS05760	COG0045	succinate-CoA ligase (ADP-forming) activity
PBT89_RS05790	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS05805	COG1064	alcohol dehydrogenase
PBT89_RS05810	COG0028	Belongs to the TPP enzyme family
PBT89_RS05815	COG0626	cystathionine gamma-synthase activity
PBT89_RS05820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PBT89_RS05845	COG3956	TIGRFAM MazG family protein
PBT89_RS05855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PBT89_RS05875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT89_RS05895	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PBT89_RS05910	COG0501	Belongs to the peptidase M48B family
PBT89_RS05915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBT89_RS05925	COG1228	amidohydrolase
PBT89_RS05935	COG2195	Cleaves the N-terminal amino acid of tripeptides
PBT89_RS05945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBT89_RS05955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PBT89_RS05960	COG0105	UTP biosynthetic process
PBT89_RS05975	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PBT89_RS05985	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PBT89_RS05995	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PBT89_RS06020	COG0681	Belongs to the peptidase S26 family
PBT89_RS06025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PBT89_RS06035	COG1475	DNA binding
PBT89_RS06040	COG1192	Involved in chromosome partitioning
PBT89_RS06045	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS06050	COG3275	phosphorelay sensor kinase activity
PBT89_RS06055	COG2201	protein-glutamate methylesterase activity
PBT89_RS06070	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT89_RS06070	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT89_RS06075	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT89_RS06085	COG0572	uridine kinase
PBT89_RS06095	COG2133	pyrroloquinoline quinone binding
PBT89_RS06135	COG3275	phosphorelay sensor kinase activity
PBT89_RS06155	COG0604	alcohol dehydrogenase
PBT89_RS06195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PBT89_RS06205	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PBT89_RS06215	COG0592	DNA-directed DNA polymerase activity
PBT89_RS06240	COG1702	phosphate starvation-inducible protein PhoH
PBT89_RS06245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PBT89_RS06250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PBT89_RS06255	COG2176	DNA-directed DNA polymerase activity
PBT89_RS06275	COG1363	Peptidase, m42
PBT89_RS06325	COG0116	Belongs to the methyltransferase superfamily
PBT89_RS06340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PBT89_RS06345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT89_RS06380	COG1104	cysteine desulfurase activity
PBT89_RS06405	COG1418	mRNA catabolic process
PBT89_RS06410	COG0656	L-ascorbic acid biosynthetic process
PBT89_RS06415	COG4974	Belongs to the 'phage' integrase family
PBT89_RS06430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PBT89_RS06440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT89_RS06450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT89_RS06470	COG2270	Major facilitator Superfamily
PBT89_RS06490	COG1595	DNA-templated transcription, initiation
PBT89_RS06495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PBT89_RS06505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PBT89_RS06510	COG2814	Major facilitator Superfamily
PBT89_RS06550	COG4302	ethanolamine ammonia-lyase activity
PBT89_RS06555	COG4303	Ethanolamine ammonia lyase large subunit
PBT89_RS06560	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PBT89_RS06575	COG1764	response to oxidative stress
PBT89_RS06580	COG1846	Transcriptional regulator
PBT89_RS06585	COG1082	Xylose isomerase domain protein TIM barrel
PBT89_RS06590	COG0590	tRNA wobble adenosine to inosine editing
PBT89_RS06595	COG3781	membrane
PBT89_RS06605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PBT89_RS06610	COG0540	Belongs to the ATCase OTCase family
PBT89_RS06620	COG1234	tRNA 3'-trailer cleavage
PBT89_RS06625	COG0259	pyridoxamine-phosphate oxidase activity
PBT89_RS06635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PBT89_RS06650	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PBT89_RS06685	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PBT89_RS06690	COG0415	Belongs to the DNA photolyase family
PBT89_RS06695	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS06730	COG0668	transmembrane transport
PBT89_RS06740	COG0424	maF-like protein
PBT89_RS06760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PBT89_RS06760	COG1333	cytochrome c biogenesis protein
PBT89_RS06785	COG1393	Belongs to the ArsC family
PBT89_RS06790	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PBT89_RS06805	COG2308	Evidence 4 Homologs of previously reported genes of
PBT89_RS06825	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PBT89_RS06840	COG0156	8-amino-7-oxononanoate synthase activity
PBT89_RS06875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PBT89_RS06890	COG0655	NAD(P)H dehydrogenase (quinone) activity
PBT89_RS06895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PBT89_RS06900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PBT89_RS06910	COG0686	Belongs to the AlaDH PNT family
PBT89_RS06925	COG0802	atpase or kinase
PBT89_RS06930	COG2204	response regulator
PBT89_RS06935	COG1078	dGTPase activity
PBT89_RS06940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT89_RS06945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PBT89_RS06945	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PBT89_RS06950	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT89_RS06955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PBT89_RS06960	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT89_RS06990	COG0612	Peptidase, M16
PBT89_RS06995	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS07010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PBT89_RS07015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PBT89_RS07025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PBT89_RS07030	COG0131	Imidazoleglycerol-phosphate dehydratase
PBT89_RS07035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PBT89_RS07040	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PBT89_RS07045	COG0107	imidazoleglycerol-phosphate synthase activity
PBT89_RS07050	COG0140	phosphoribosyl-ATP diphosphatase activity
PBT89_RS07050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PBT89_RS07060	COG1741	Belongs to the pirin family
PBT89_RS07070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PBT89_RS07095	COG0598	Magnesium transport protein CorA
PBT89_RS07100	COG2706	6-phosphogluconolactonase activity
PBT89_RS07105	COG1278	Cold shock
PBT89_RS07125	COG2826	transposase and inactivated derivatives, IS30 family
PBT89_RS07135	COG3547	Transposase (IS116 IS110 IS902 family)
PBT89_RS07185	COG1678	Uncharacterized ACR, COG1678
PBT89_RS07195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PBT89_RS07200	COG0514	ATP-dependent DNA helicase (RecQ)
PBT89_RS07220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PBT89_RS07230	COG4774	siderophore transport
PBT89_RS07240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PBT89_RS07240	COG0321	lipoyl(octanoyl) transferase activity
PBT89_RS07255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PBT89_RS07260	COG0280	phosphate acetyltransferase
PBT89_RS07260	COG0857	belongs to the CobB CobQ family
PBT89_RS07275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PBT89_RS07295	COG1136	(ABC) transporter
PBT89_RS07300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT89_RS07310	COG4771	TonB-dependent receptor
PBT89_RS07335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBT89_RS07340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PBT89_RS07350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PBT89_RS07370	COG1629	transport
PBT89_RS07375	COG0702	epimerase
PBT89_RS07380	COG3534	alpha-L-arabinofuranosidase
PBT89_RS07385	COG3507	Belongs to the glycosyl hydrolase 43 family
PBT89_RS07395	COG3507	Belongs to the glycosyl hydrolase 43 family
PBT89_RS07400	COG3507	Belongs to the glycosyl hydrolase 43 family
PBT89_RS07405	COG3940	Belongs to the glycosyl hydrolase 43 family
PBT89_RS07415	COG0235	Class ii aldolase
PBT89_RS07420	COG2160	L-arabinose isomerase activity
PBT89_RS07480	COG2826	transposase and inactivated derivatives, IS30 family
PBT89_RS07490	COG3547	Transposase (IS116 IS110 IS902 family)
PBT89_RS07535	COG3547	Transposase (IS116 IS110 IS902 family)
PBT89_RS07550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PBT89_RS07560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PBT89_RS07575	COG4115	mRNA cleavage
PBT89_RS07580	COG2161	toxin-antitoxin pair type II binding
PBT89_RS07635	COG3547	Transposase (IS116 IS110 IS902 family)
PBT89_RS07685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT89_RS07690	COG3547	Transposase (IS116 IS110 IS902 family)
PBT89_RS07695	COG3177	Filamentation induced by cAMP protein fic
PBT89_RS07735	COG3547	Transposase (IS116 IS110 IS902 family)
PBT89_RS07800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PBT89_RS07860	COG4974	Belongs to the 'phage' integrase family
PBT89_RS07875	COG1482	cell wall glycoprotein biosynthetic process
PBT89_RS07915	COG0006	proline dipeptidase activity
PBT89_RS07920	COG3250	beta-galactosidase activity
PBT89_RS07930	COG1917	Cupin 2, conserved barrel domain protein
PBT89_RS07930	COG4977	sequence-specific DNA binding
PBT89_RS07935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBT89_RS07945	COG3938	Belongs to the proline racemase family
PBT89_RS07950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PBT89_RS07955	COG1629	transport
PBT89_RS07955	COG4206	TonB-dependent receptor
PBT89_RS07960	COG0561	phosphatase activity
PBT89_RS07965	COG1506	peptidase
PBT89_RS07965	COG0823	Involved in the tonB-independent uptake of proteins
PBT89_RS07980	COG3534	alpha-L-arabinofuranosidase
PBT89_RS07995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PBT89_RS08035	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PBT89_RS08045	COG1764	response to oxidative stress
PBT89_RS08050	COG1047	Peptidyl-prolyl cis-trans
PBT89_RS08075	COG0527	aspartate kinase activity
PBT89_RS08085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBT89_RS08090	COG3265	gluconokinase activity
PBT89_RS08100	COG0217	transcriptional regulatory protein
PBT89_RS08105	COG2154	pterin-4-alpha-carbinolamine dehydratase
PBT89_RS08115	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PBT89_RS08120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PBT89_RS08120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PBT89_RS08125	COG2986	histidine ammonia-lyase
PBT89_RS08130	COG0542	response to heat
PBT89_RS08135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PBT89_RS08140	COG3063	Type IV pilus biogenesis stability protein PilW
PBT89_RS08150	COG0183	Belongs to the thiolase family
PBT89_RS08180	COG1012	belongs to the aldehyde dehydrogenase family
PBT89_RS08190	COG1051	belongs to the nudix hydrolase family
PBT89_RS08195	COG1607	acyl-coa hydrolase
PBT89_RS08200	COG0668	transmembrane transport
PBT89_RS08210	COG0668	transmembrane transport
PBT89_RS08215	COG2814	Major facilitator Superfamily
PBT89_RS08225	COG0401	homolog of Blt101
PBT89_RS08255	COG2072	flavoprotein involved in K transport
PBT89_RS08260	COG4221	oxidoreductase activity
PBT89_RS08265	COG2130	NADP-dependent
PBT89_RS08270	COG1289	transmembrane transporter activity
PBT89_RS08285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PBT89_RS08295	COG1902	pentaerythritol trinitrate reductase activity
PBT89_RS08325	COG0583	DNA-binding transcription factor activity
PBT89_RS08330	COG2855	membrane
PBT89_RS08335	COG0698	ribose 5-phosphate isomerase
PBT89_RS08340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PBT89_RS08345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PBT89_RS08350	COG0363	glucosamine-6-phosphate deaminase activity
PBT89_RS08365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PBT89_RS08370	COG3384	dioxygenase
PBT89_RS08385	COG2723	6-phospho-beta-galactosidase activity
PBT89_RS08390	COG1278	Cold shock
PBT89_RS08530	COG0022	dehydrogenase e1 component
PBT89_RS08540	COG0023	Translation Initiation Factor
PBT89_RS08550	COG0813	purine-nucleoside phosphorylase activity
PBT89_RS08555	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PBT89_RS08580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PBT89_RS08585	COG1193	negative regulation of DNA recombination
PBT89_RS08590	COG3011	Protein conserved in bacteria
PBT89_RS08600	COG1301	dicarboxylic acid transport
PBT89_RS08605	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PBT89_RS08620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PBT89_RS08630	COG0693	protein deglycase activity
PBT89_RS08645	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PBT89_RS08650	COG1522	sequence-specific DNA binding
PBT89_RS08670	COG1970	mechanosensitive ion channel activity
PBT89_RS08700	COG2226	methyltransferase
PBT89_RS08715	COG3537	Alpha-1,2-mannosidase
PBT89_RS08730	COG0247	lactate metabolic process
PBT89_RS08740	COG0438	transferase activity, transferring glycosyl groups
PBT89_RS08745	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT89_RS08755	COG0247	lactate metabolic process
PBT89_RS08755	COG2181	nitrate reductase activity
PBT89_RS08760	COG2181	nitrate reductase activity
PBT89_RS08760	COG0247	lactate metabolic process
PBT89_RS08770	COG0860	N-Acetylmuramoyl-L-alanine amidase
PBT89_RS08780	COG0251	oxidation-reduction process
PBT89_RS08785	COG0667	Aldo Keto reductase
PBT89_RS08795	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
PBT89_RS08805	COG1803	Methylglyoxal synthase
PBT89_RS08810	COG0205	6-phosphofructokinase activity
PBT89_RS08820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PBT89_RS08825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PBT89_RS08870	COG1215	transferase activity, transferring glycosyl groups
PBT89_RS08895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBT89_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
PBT89_RS08955	COG4974	Belongs to the 'phage' integrase family
PBT89_RS08975	COG2249	NAD(P)H dehydrogenase (quinone) activity
PBT89_RS08980	COG1078	dGTPase activity
PBT89_RS09030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PBT89_RS09035	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PBT89_RS09060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PBT89_RS09090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT89_RS09100	COG0124	histidyl-tRNA synthetase
PBT89_RS09105	COG0577	efflux transmembrane transporter activity
PBT89_RS09115	COG0359	binds to the 23S rRNA
PBT89_RS09120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PBT89_RS09125	COG0360	Binds together with S18 to 16S ribosomal RNA
PBT89_RS09130	COG3279	Response regulator of the LytR AlgR family
PBT89_RS09135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PBT89_RS09150	COG1295	ribonuclease BN
PBT89_RS09160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PBT89_RS09165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PBT89_RS09190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PBT89_RS09205	COG0670	Belongs to the BI1 family
PBT89_RS09215	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
PBT89_RS09250	COG1842	Phage shock protein A
PBT89_RS09260	COG1396	sequence-specific DNA binding
PBT89_RS09285	COG0589	response to stress
PBT89_RS09290	COG0069	glutamate synthase activity
PBT89_RS09300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PBT89_RS09345	COG1045	serine acetyltransferase
PBT89_RS09355	COG2936	dipeptidyl-peptidase activity
PBT89_RS09360	COG4771	TonB-dependent receptor
PBT89_RS09365	COG1396	sequence-specific DNA binding
PBT89_RS09410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBT89_RS09420	COG1322	Protein conserved in bacteria
PBT89_RS09430	COG1607	acyl-coa hydrolase
PBT89_RS09450	COG2363	Small membrane protein
PBT89_RS09455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PBT89_RS09460	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PBT89_RS09475	COG2234	aminopeptidase activity
PBT89_RS09490	COG1741	Belongs to the pirin family
PBT89_RS09500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT89_RS09525	COG0254	rRNA binding
PBT89_RS09535	COG0463	Glycosyl transferase, family 2
PBT89_RS09540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PBT89_RS09545	COG1132	(ABC) transporter
PBT89_RS09570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PBT89_RS09570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PBT89_RS09575	COG2356	endonuclease I
PBT89_RS09580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PBT89_RS09580	COG0047	phosphoribosylformylglycinamidine synthase activity
PBT89_RS09590	COG1022	Amp-dependent synthetase and ligase
PBT89_RS09595	COG1846	Transcriptional regulator
PBT89_RS09600	COG1024	Enoyl-CoA hydratase
PBT89_RS09600	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBT89_RS09610	COG0183	Belongs to the thiolase family
PBT89_RS09620	COG1960	acyl-CoA dehydrogenase activity
PBT89_RS09635	COG3387	PFAM Glycoside hydrolase 15-related
PBT89_RS09640	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PBT89_RS09680	COG1597	lipid kinase activity
PBT89_RS09685	COG4771	TonB-dependent receptor
PBT89_RS09690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PBT89_RS09730	COG2211	Major facilitator Superfamily
PBT89_RS09735	COG0673	inositol 2-dehydrogenase activity
PBT89_RS09750	COG1595	DNA-templated transcription, initiation
PBT89_RS09760	COG3279	Response regulator of the LytR AlgR family
PBT89_RS09775	COG3275	phosphorelay sensor kinase activity
PBT89_RS09785	COG4206	TonB-dependent receptor
PBT89_RS09785	COG1629	transport
PBT89_RS09810	COG0494	nUDIX hydrolase
PBT89_RS09815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBT89_RS09845	COG0714	Associated with various cellular activities
PBT89_RS09905	COG0492	ferredoxin-NADP+ reductase activity
PBT89_RS09910	COG2860	membrane
PBT89_RS09935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PBT89_RS09940	COG0439	Biotin carboxylase
PBT89_RS09950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT89_RS09975	COG4771	TonB-dependent receptor
PBT89_RS09990	COG1476	TRANSCRIPTIONal
PBT89_RS09995	COG3940	Belongs to the glycosyl hydrolase 43 family
PBT89_RS10005	COG1271	oxidase subunit
PBT89_RS10010	COG0730	response to heat
PBT89_RS10025	COG1733	regulation of RNA biosynthetic process
PBT89_RS10040	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PBT89_RS10045	COG0352	thiamine-phosphate diphosphorylase activity
PBT89_RS10050	COG0351	phosphomethylpyrimidine kinase
PBT89_RS10055	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PBT89_RS10085	COG1785	Belongs to the alkaline phosphatase family
PBT89_RS10095	COG4206	TonB-dependent receptor
PBT89_RS10095	COG1629	transport
PBT89_RS10105	COG4771	TonB-dependent receptor
PBT89_RS10130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT89_RS10155	COG3279	Response regulator of the LytR AlgR family
PBT89_RS10185	COG0714	Associated with various cellular activities
PBT89_RS10195	COG0312	modulator of DNA gyrase
PBT89_RS10200	COG0312	modulator of DNA gyrase
PBT89_RS10225	COG4181	ATPase activity
PBT89_RS10240	COG0584	glycerophosphoryl diester phosphodiesterase
PBT89_RS10365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PBT89_RS10390	COG0738	Major facilitator superfamily
PBT89_RS10400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PBT89_RS10430	COG3278	Belongs to the heme-copper respiratory oxidase family
PBT89_RS10450	COG1215	transferase activity, transferring glycosyl groups
PBT89_RS10480	COG2084	Dehydrogenase
PBT89_RS10495	COG0339	signal peptide processing
PBT89_RS10510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT89_RS10560	COG1187	pseudouridine synthase activity
PBT89_RS10575	COG4251	negative regulation of phosphorylation
PBT89_RS10585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBT89_RS10590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PBT89_RS10595	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PBT89_RS10605	COG4651	solute:proton antiporter activity
PBT89_RS10605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PBT89_RS10610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PBT89_RS10625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PBT89_RS10630	COG0083	homoserine kinase activity
PBT89_RS10635	COG0527	aspartate kinase activity
PBT89_RS10635	COG0460	homoserine dehydrogenase
PBT89_RS10655	COG2198	Histidine kinase
PBT89_RS10655	COG0784	Response regulator, receiver
PBT89_RS10655	COG0643	Histidine kinase
PBT89_RS10670	COG1086	Polysaccharide biosynthesis protein
PBT89_RS10675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PBT89_RS10680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PBT89_RS10685	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PBT89_RS10690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT89_RS10710	COG0783	Belongs to the Dps family
PBT89_RS10715	COG0668	transmembrane transport
PBT89_RS10740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT89_RS10765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PBT89_RS10775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PBT89_RS10780	COG1611	Belongs to the LOG family
PBT89_RS10790	COG0022	dehydrogenase e1 component
PBT89_RS10830	COG2996	Protein conserved in bacteria
PBT89_RS10845	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PBT89_RS10890	COG0443	Heat shock 70 kDa protein
PBT89_RS10895	COG1760	l-serine dehydratase
PBT89_RS10910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PBT89_RS10920	COG0564	pseudouridine synthase activity
PBT89_RS10925	COG2321	neutral zinc metallopeptidase
PBT89_RS10930	COG3387	PFAM Glycoside hydrolase 15-related
PBT89_RS10945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PBT89_RS10950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PBT89_RS10955	COG0066	3-isopropylmalate dehydratase activity
PBT89_RS10960	COG0473	3-isopropylmalate dehydrogenase activity
PBT89_RS10975	COG0165	Argininosuccinate lyase
PBT89_RS10980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PBT89_RS10985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PBT89_RS10990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PBT89_RS10995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT89_RS11000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBT89_RS11005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PBT89_RS11010	COG0137	argininosuccinate synthase activity
PBT89_RS11020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PBT89_RS11025	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PBT89_RS11035	COG0028	Belongs to the TPP enzyme family
PBT89_RS11045	COG3153	acetyltransferase
PBT89_RS11045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PBT89_RS11055	COG1984	allophanate hydrolase subunit 2
PBT89_RS11060	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PBT89_RS11070	COG1914	H( )-stimulated, divalent metal cation uptake system
PBT89_RS11080	COG0606	chelatase, subunit chli
PBT89_RS11090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBT89_RS11095	COG0205	6-phosphofructokinase activity
PBT89_RS11100	COG0366	Alpha amylase catalytic
PBT89_RS11105	COG1082	Xylose isomerase domain protein TIM barrel
PBT89_RS11110	COG1554	hydrolase, family 65, central catalytic
PBT89_RS11115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PBT89_RS11130	COG4206	TonB-dependent receptor
PBT89_RS11130	COG1629	transport
PBT89_RS11135	COG0561	phosphatase activity
PBT89_RS11175	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PBT89_RS11180	COG1085	galactose-1-phosphate uridylyltransferase
PBT89_RS11205	COG0037	tRNA processing
PBT89_RS11225	COG0513	Belongs to the DEAD box helicase family
PBT89_RS11230	COG2972	Histidine kinase
PBT89_RS11240	COG3279	Response regulator of the LytR AlgR family
PBT89_RS11265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT89_RS11270	COG1757	Na H antiporter
PBT89_RS11275	COG0450	alkyl hydroperoxide reductase
PBT89_RS11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT89_RS11300	COG0596	Alpha beta hydrolase
PBT89_RS11305	COG1674	ftsk spoiiie
PBT89_RS11320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PBT89_RS11320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PBT89_RS11335	COG4771	TonB-dependent receptor
PBT89_RS11340	COG0561	phosphatase activity
PBT89_RS11360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBT89_RS11365	COG0420	3'-5' exonuclease activity
PBT89_RS11370	COG0419	ATPase involved in DNA repair
PBT89_RS11380	COG1272	protein, Hemolysin III
PBT89_RS11395	COG1132	(ABC) transporter
PBT89_RS11420	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PBT89_RS11420	COG2755	lipolytic protein G-D-S-L family
PBT89_RS11430	COG3608	succinylglutamate desuccinylase aspartoacylase
PBT89_RS11435	COG1858	cytochrome C peroxidase
PBT89_RS11465	COG2197	response regulator
PBT89_RS11470	COG4585	Histidine kinase
PBT89_RS11475	COG5002	protein histidine kinase activity
PBT89_RS11475	COG5000	phosphorelay sensor kinase activity
PBT89_RS11495	COG0656	L-ascorbic acid biosynthetic process
PBT89_RS11525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT89_RS11535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PBT89_RS11545	COG0154	amidase activity
PBT89_RS11550	COG0552	protein localization to endoplasmic reticulum
PBT89_RS11560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PBT89_RS11565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PBT89_RS11570	COG1058	Belongs to the CinA family
PBT89_RS11570	COG1546	Belongs to the CinA family
PBT89_RS11580	COG0179	Fumarylacetoacetate (FAA) hydrolase
PBT89_RS11590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PBT89_RS11595	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT89_RS11600	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PBT89_RS11620	COG0488	(ABC) transporter
PBT89_RS11630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PBT89_RS11635	COG0300	oxidoreductase activity
PBT89_RS11670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PBT89_RS11685	COG3118	belongs to the thioredoxin family
PBT89_RS11690	COG0542	response to heat
PBT89_RS11710	COG1012	belongs to the aldehyde dehydrogenase family
PBT89_RS11730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PBT89_RS11745	COG0242	peptide deformylase activity
PBT89_RS11750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PBT89_RS11755	COG2171	N-acyltransferase activity
PBT89_RS11780	COG1216	Glycosyl transferase, family 2
PBT89_RS11790	COG0617	tRNA 3'-terminal CCA addition
PBT89_RS11790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PBT89_RS11790	COG0517	IMP dehydrogenase activity
PBT89_RS11795	COG1612	heme a metabolic process
PBT89_RS11830	COG0556	nucleotide-excision repair
PBT89_RS11840	COG2204	response regulator
PBT89_RS11850	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PBT89_RS11850	COG3264	Mechanosensitive ion channel
PBT89_RS11855	COG1668	transmembrane transport
PBT89_RS11860	COG4152	abc transporter atp-binding protein
PBT89_RS11870	COG0484	heat shock protein binding
PBT89_RS11875	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PBT89_RS11890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PBT89_RS11890	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PBT89_RS11900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PBT89_RS11925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PBT89_RS11930	COG0347	Belongs to the P(II) protein family
PBT89_RS11935	COG0004	ammonium transporteR
PBT89_RS11965	COG1522	sequence-specific DNA binding
PBT89_RS11975	COG2095	MarC family integral membrane protein
PBT89_RS11980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT89_RS11980	COG1703	isobutyryl-CoA mutase activity
PBT89_RS11980	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT89_RS11985	COG0788	formyltetrahydrofolate deformylase activity
PBT89_RS12000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PBT89_RS12005	COG0284	orotidine-5'-phosphate decarboxylase activity
PBT89_RS12010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PBT89_RS12015	COG1131	(ABC) transporter
PBT89_RS12025	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PBT89_RS12035	COG0174	glutamine synthetase
PBT89_RS12080	COG2814	Major facilitator Superfamily
PBT89_RS12095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT89_RS12125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT89_RS12135	COG4771	TonB-dependent receptor
PBT89_RS12150	COG0386	Belongs to the glutathione peroxidase family
PBT89_RS12165	COG0523	cobalamin synthesis protein
PBT89_RS12175	COG1785	Belongs to the alkaline phosphatase family
PBT89_RS12180	COG2076	Multidrug Resistance protein
PBT89_RS12185	COG3152	Membrane
PBT89_RS12200	COG2264	protein methyltransferase activity
PBT89_RS12205	COG0149	triose-phosphate isomerase activity
PBT89_RS12220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PBT89_RS12225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PBT89_RS12240	COG1132	(ABC) transporter
PBT89_RS12245	COG0101	tRNA pseudouridine synthase activity
PBT89_RS12265	COG0745	RESPONSE REGULATOR receiver
PBT89_RS12270	COG5002	protein histidine kinase activity
PBT89_RS12280	COG0740	serine-type endopeptidase activity
PBT89_RS12295	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PBT89_RS12300	COG3118	belongs to the thioredoxin family
PBT89_RS12320	COG2226	methyltransferase
PBT89_RS12325	COG1477	protein flavinylation
PBT89_RS12340	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBT89_RS12345	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBT89_RS12355	COG1805	sodium ion transport
PBT89_RS12360	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBT89_RS12375	COG2967	ApaG domain
PBT89_RS12385	COG1012	belongs to the aldehyde dehydrogenase family
PBT89_RS12395	COG0357	Ribosomal RNA small subunit methyltransferase G
PBT89_RS12400	COG3239	Fatty acid desaturase
PBT89_RS12405	COG0436	Aminotransferase
PBT89_RS12410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBT89_RS12415	COG0569	domain protein
PBT89_RS12420	COG2226	methyltransferase
PBT89_RS12430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBT89_RS12440	COG0191	fructose-bisphosphate aldolase activity
PBT89_RS12445	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PBT89_RS12450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PBT89_RS12455	COG1185	polyribonucleotide nucleotidyltransferase activity
PBT89_RS12460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBT89_RS12470	COG0095	Lipoate-protein ligase
PBT89_RS12475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PBT89_RS12480	COG0492	ferredoxin-NADP+ reductase activity
PBT89_RS12495	COG2814	Major facilitator Superfamily
PBT89_RS12530	COG3250	beta-galactosidase activity
PBT89_RS12535	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PBT89_RS12550	COG1629	transport
PBT89_RS12555	COG3292	Two component regulator propeller
PBT89_RS12555	COG0745	RESPONSE REGULATOR receiver
PBT89_RS12555	COG2205	protein histidine kinase activity
PBT89_RS12560	COG4677	pectinesterase activity
PBT89_RS12565	COG0657	acetylesterase activity
PBT89_RS12570	COG0432	Pfam Uncharacterised protein family UPF0047
PBT89_RS12580	COG0305	Participates in initiation and elongation during chromosome replication
PBT89_RS12585	COG0825	malonyl-CoA metabolic process
PBT89_RS12595	COG0343	queuine tRNA-ribosyltransferase activity
PBT89_RS12605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PBT89_RS12620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PBT89_RS12625	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PBT89_RS12630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PBT89_RS12650	COG0019	diaminopimelate decarboxylase activity
PBT89_RS12660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PBT89_RS12670	COG1233	COG1233 Phytoene dehydrogenase and related
PBT89_RS12690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT89_RS12695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PBT89_RS12700	COG0714	Associated with various cellular activities
PBT89_RS12705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBT89_RS12720	COG0517	IMP dehydrogenase activity
PBT89_RS12720	COG0516	GMP reductase activity
PBT89_RS12740	COG0167	dihydroorotate dehydrogenase activity
PBT89_RS12745	COG2195	Cleaves the N-terminal amino acid of tripeptides
PBT89_RS12750	COG1862	Preprotein translocase
PBT89_RS12760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PBT89_RS12770	COG1132	(ABC) transporter
PBT89_RS12785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBT89_RS12790	COG0569	domain protein
PBT89_RS12795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT89_RS12805	COG0450	alkyl hydroperoxide reductase
PBT89_RS12810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBT89_RS12815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PBT89_RS12835	COG2884	Cell division ATP-binding protein ftsE
PBT89_RS12845	COG1858	cytochrome C peroxidase
PBT89_RS12870	COG1217	gtp-binding protein TYPA
PBT89_RS12875	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PBT89_RS12880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT89_RS12935	COG3590	peptidase
PBT89_RS12965	COG2205	protein histidine kinase activity
PBT89_RS12965	COG0745	RESPONSE REGULATOR receiver
PBT89_RS12965	COG3292	Two component regulator propeller
PBT89_RS12995	COG4771	TonB-dependent receptor
PBT89_RS13015	COG1216	Glycosyl transferase, family 2
PBT89_RS13020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT89_RS13030	COG0438	transferase activity, transferring glycosyl groups
PBT89_RS13045	COG0438	transferase activity, transferring glycosyl groups
PBT89_RS13055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PBT89_RS13070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PBT89_RS13085	COG2327	Polysaccharide pyruvyl transferase
PBT89_RS13110	COG1309	transcriptional regulator
PBT89_RS13130	COG0784	Response regulator, receiver
PBT89_RS13140	COG4251	negative regulation of phosphorylation
PBT89_RS13150	COG5002	protein histidine kinase activity
PBT89_RS13160	COG3279	Response regulator of the LytR AlgR family
PBT89_RS13170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT89_RS13175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT89_RS13190	COG1611	Belongs to the LOG family
PBT89_RS13195	COG2890	protein-(glutamine-N5) methyltransferase activity
PBT89_RS13205	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBT89_RS13205	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBT89_RS13215	COG1739	Uncharacterized protein family UPF0029
PBT89_RS13220	COG0824	Thioesterase
PBT89_RS13225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PBT89_RS13230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PBT89_RS13245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PBT89_RS13255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PBT89_RS13260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBT89_RS13270	COG0336	Belongs to the RNA methyltransferase TrmD family
PBT89_RS13275	COG0335	large ribosomal subunit rRNA binding
PBT89_RS13285	COG2814	Major facilitator Superfamily
PBT89_RS13355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PBT89_RS13360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PBT89_RS13365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PBT89_RS13370	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PBT89_RS13380	COG1054	Belongs to the UPF0176 family
PBT89_RS13385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT89_RS13395	COG0778	Nitroreductase
PBT89_RS13405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PBT89_RS13410	COG0512	Glutamine amidotransferase of anthranilate synthase
PBT89_RS13410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PBT89_RS13415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PBT89_RS13420	COG0134	indole-3-glycerol-phosphate synthase activity
PBT89_RS13425	COG0135	phosphoribosylanthranilate isomerase activity
PBT89_RS13430	COG0133	tryptophan synthase activity
PBT89_RS13435	COG0159	tryptophan synthase activity
PBT89_RS13460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PBT89_RS13465	COG3022	response to hydroperoxide
PBT89_RS13470	COG0564	pseudouridine synthase activity
PBT89_RS13480	COG1181	Belongs to the D-alanine--D-alanine ligase family
PBT89_RS13490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PBT89_RS13500	COG4771	TonB-dependent receptor
PBT89_RS13515	COG1051	belongs to the nudix hydrolase family
PBT89_RS13520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PBT89_RS13535	COG0799	negative regulation of ribosome biogenesis
PBT89_RS13540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PBT89_RS13550	COG4589	Belongs to the CDS family
PBT89_RS13555	COG0688	phosphatidylethanolamine metabolic process
PBT89_RS13565	COG0525	valine-tRNA ligase activity
PBT89_RS13575	COG0436	Aminotransferase
PBT89_RS13580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PBT89_RS13605	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PBT89_RS13610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBT89_RS13620	COG1663	tetraacyldisaccharide 4'-kinase activity
PBT89_RS13625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PBT89_RS13645	COG3263	regulation of cellular component size
PBT89_RS13650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PBT89_RS13670	COG0415	Belongs to the DNA photolyase family
PBT89_RS13675	COG3046	protein related to deoxyribodipyrimidine photolyase
PBT89_RS13695	COG3844	kynureninase activity
PBT89_RS13705	COG0671	phosphoesterase, PA-phosphatase related
PBT89_RS13710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBT89_RS13745	COG3340	Belongs to the peptidase S51 family
PBT89_RS13750	COG2066	Belongs to the glutaminase family
PBT89_RS13755	COG0268	Binds directly to 16S ribosomal RNA
PBT89_RS13770	COG0442	prolyl-tRNA aminoacylation
PBT89_RS13790	COG0302	gtp cyclohydrolase
PBT89_RS13795	COG0215	cysteine-tRNA ligase activity
PBT89_RS13800	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PBT89_RS13805	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PBT89_RS13815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PBT89_RS13825	COG0187	DNA topoisomerase II activity
PBT89_RS13835	COG0602	queuosine metabolic process
PBT89_RS13845	COG1619	proteins homologs of microcin C7 resistance protein MccF
PBT89_RS13855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PBT89_RS13860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PBT89_RS13875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PBT89_RS13880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PBT89_RS13890	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PBT89_RS13895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBT89_RS13900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PBT89_RS13915	COG0275	rRNA processing
PBT89_RS13920	COG2001	Belongs to the MraZ family
PBT89_RS13925	COG2267	carboxylic ester hydrolase activity
PBT89_RS13930	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PBT89_RS13950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PBT89_RS13955	COG2197	response regulator
PBT89_RS13960	COG0358	DNA primase activity
PBT89_RS13960	COG0305	Participates in initiation and elongation during chromosome replication
PBT89_RS13980	COG1187	pseudouridine synthase activity
PBT89_RS14000	COG3339	Conserved Protein
PBT89_RS14005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PBT89_RS14015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PBT89_RS14020	COG0018	arginyl-trna synthetase
PBT89_RS14030	COG2095	MarC family integral membrane protein
PBT89_RS14040	COG1090	epimerase
PBT89_RS14045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PBT89_RS14055	COG1834	amidinotransferase
PBT89_RS14065	COG0297	glycogen (starch) synthase activity
PBT89_RS14070	COG0148	phosphopyruvate hydratase activity
PBT89_RS14075	COG0505	Belongs to the CarA family
PBT89_RS14080	COG0203	ribosomal protein L17
PBT89_RS14085	COG0202	RNA polymerase activity
PBT89_RS14090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PBT89_RS14095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PBT89_RS14100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PBT89_RS14105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PBT89_RS14110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PBT89_RS14120	COG0200	Binds to the 23S rRNA
PBT89_RS14125	COG1841	ribosomal large subunit assembly
PBT89_RS14130	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PBT89_RS14135	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PBT89_RS14140	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PBT89_RS14145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PBT89_RS14150	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PBT89_RS14155	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PBT89_RS14160	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PBT89_RS14165	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PBT89_RS14170	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PBT89_RS14175	COG0255	Belongs to the universal ribosomal protein uL29 family
PBT89_RS14180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PBT89_RS14185	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PBT89_RS14190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PBT89_RS14195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PBT89_RS14200	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PBT89_RS14205	COG0089	rRNA binding
PBT89_RS14210	COG0088	Forms part of the polypeptide exit tunnel
PBT89_RS14215	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PBT89_RS14220	COG0051	transcription antitermination factor activity, RNA binding
PBT89_RS14225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PBT89_RS14230	COG0049	tRNA binding
PBT89_RS14235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PBT89_RS14240	COG4771	TonB-dependent receptor
PBT89_RS14255	COG4771	TonB-dependent receptor
PBT89_RS14265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBT89_RS14275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PBT89_RS14295	COG2003	Belongs to the UPF0758 family
PBT89_RS14300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PBT89_RS14330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PBT89_RS14340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PBT89_RS14345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PBT89_RS14350	COG0339	signal peptide processing
PBT89_RS14370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PBT89_RS14370	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PBT89_RS14385	COG1215	transferase activity, transferring glycosyl groups
PBT89_RS14395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PBT89_RS14400	COG1127	ABC transporter
PBT89_RS14430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PBT89_RS14435	COG0295	cytidine deaminase activity
PBT89_RS14445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT89_RS14450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PBT89_RS14465	COG0285	dihydrofolate synthase activity
PBT89_RS14475	COG0848	biopolymer transport protein
PBT89_RS14480	COG0811	peptide transport
PBT89_RS14485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PBT89_RS14495	COG1960	acyl-CoA dehydrogenase activity
PBT89_RS14500	COG0069	glutamate synthase activity
PBT89_RS14500	COG0067	glutamate synthase
PBT89_RS14500	COG0070	glutamate synthase
PBT89_RS14545	COG4771	TonB-dependent receptor
PBT89_RS14550	COG0702	epimerase
PBT89_RS14565	COG4771	TonB-dependent receptor
PBT89_RS14570	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PBT89_RS14575	COG0321	lipoyl(octanoyl) transferase activity
PBT89_RS14580	COG0401	homolog of Blt101
PBT89_RS14585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PBT89_RS14600	COG0701	Predicted permease
PBT89_RS14605	COG2217	Heavy metal translocating P-type atpase
PBT89_RS14610	COG1917	Cupin 2, conserved barrel domain protein
PBT89_RS14610	COG4977	sequence-specific DNA binding
PBT89_RS14630	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBT89_RS14660	COG0138	bifunctional purine biosynthesis protein purh
PBT89_RS14665	COG1077	Cell shape determining protein MreB Mrl
PBT89_RS14680	COG0768	penicillin binding
PBT89_RS14685	COG0772	Belongs to the SEDS family
PBT89_RS14695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PBT89_RS14705	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT89_RS14710	COG0791	NLP P60 protein
PBT89_RS14715	COG0658	competence protein
PBT89_RS14715	COG2333	competence protein COMEC
PBT89_RS14725	COG3104	oligopeptide transport
PBT89_RS14730	COG1506	peptidase
PBT89_RS14730	COG0823	Involved in the tonB-independent uptake of proteins
PBT89_RS14745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBT89_RS14750	COG1253	flavin adenine dinucleotide binding
PBT89_RS14765	COG0457	Tetratricopeptide repeat
PBT89_RS14775	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PBT89_RS14795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PBT89_RS14800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT89_RS14805	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT89_RS14815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PBT89_RS14825	COG0544	peptidyl-prolyl cis-trans isomerase activity
PBT89_RS14845	COG0596	Alpha beta hydrolase
PBT89_RS14850	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PBT89_RS14860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PBT89_RS14875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PBT89_RS14890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PBT89_RS14910	COG1331	Highly conserved protein containing a thioredoxin domain
PBT89_RS14915	COG0668	transmembrane transport
PBT89_RS14920	COG1214	PFAM Peptidase M22, glycoprotease
PBT89_RS14935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT89_RS14940	COG0577	efflux transmembrane transporter activity
PBT89_RS14940	COG1136	(ABC) transporter
PBT89_RS14945	COG0577	efflux transmembrane transporter activity
PBT89_RS14945	COG1136	(ABC) transporter
PBT89_RS14950	COG1136	(ABC) transporter
PBT89_RS14960	COG2322	membrane
PBT89_RS14965	COG1999	signal sequence binding
PBT89_RS14985	COG1845	cytochrome c oxidase, subunit III
PBT89_RS14990	COG0109	protoheme IX farnesyltransferase activity
PBT89_RS15010	COG0509	glycine decarboxylation via glycine cleavage system
PBT89_RS15020	COG0632	four-way junction helicase activity
PBT89_RS15025	COG0280	phosphate acetyltransferase
PBT89_RS15025	COG0281	malic enzyme
PBT89_RS15035	COG1595	DNA-templated transcription, initiation
PBT89_RS15040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PBT89_RS15045	COG2124	cytochrome p450
PBT89_RS15050	COG2255	four-way junction helicase activity
PBT89_RS15055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PBT89_RS15080	COG0052	Belongs to the universal ribosomal protein uS2 family
PBT89_RS15085	COG0437	4 iron, 4 sulfur cluster binding
PBT89_RS15100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PBT89_RS15105	COG0195	Participates in both transcription termination and antitermination
PBT89_RS15105	COG2251	uridine kinase activity
PBT89_RS15110	COG0779	Required for maturation of 30S ribosomal subunits
PBT89_RS15115	COG0589	response to stress
PBT89_RS15180	COG0297	glycogen (starch) synthase activity
PBT89_RS15210	COG1216	Glycosyl transferase, family 2
PBT89_RS15235	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PBT89_RS15240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT89_RS15245	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PBT89_RS15260	COG0175	sulfate reduction
PBT89_RS15265	COG0529	Catalyzes the synthesis of activated sulfate
PBT89_RS15270	COG0662	Cupin 2, conserved barrel domain protein
PBT89_RS15270	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PBT89_RS15295	COG0471	metal ion transport
PBT89_RS15295	COG3273	potassium ion transport
PBT89_RS15325	COG1446	asparaginase
PBT89_RS15345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PBT89_RS15350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PBT89_RS15355	COG0052	Belongs to the universal ribosomal protein uS2 family
PBT89_RS15360	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PBT89_RS15365	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PBT89_RS15370	COG0513	Belongs to the DEAD box helicase family
PBT89_RS15375	COG1960	acyl-CoA dehydrogenase activity
PBT89_RS15390	COG0492	ferredoxin-NADP+ reductase activity
PBT89_RS15400	COG0489	protein tyrosine kinase activity
PBT89_RS15415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PBT89_RS15425	COG5002	protein histidine kinase activity
PBT89_RS15430	COG0745	RESPONSE REGULATOR receiver
PBT89_RS15435	COG4771	TonB-dependent receptor
PBT89_RS15455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PBT89_RS15470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PBT89_RS15475	COG0463	Glycosyl transferase, family 2
PBT89_RS15490	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PBT89_RS15495	COG2363	Small membrane protein
PBT89_RS15505	COG1522	sequence-specific DNA binding
PBT89_RS15510	COG1528	Iron-storage protein
PBT89_RS15515	COG0423	glycine-tRNA ligase activity
PBT89_RS15555	COG1201	RNA secondary structure unwinding
PBT89_RS15560	COG1793	dna ligase
PBT89_RS15575	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PBT89_RS15590	COG0527	aspartate kinase activity
PBT89_RS15600	COG0702	epimerase
PBT89_RS15605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PBT89_RS15610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBT89_RS15615	COG2239	Acts as a magnesium transporter
PBT89_RS15620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PBT89_RS15640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PBT89_RS15650	COG0196	riboflavin kinase activity
PBT89_RS15655	COG0193	aminoacyl-tRNA hydrolase activity
PBT89_RS15660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PBT89_RS15665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PBT89_RS15685	COG2197	response regulator
PBT89_RS15690	COG4585	Histidine kinase
PBT89_RS15710	COG0793	Belongs to the peptidase S41A family
PBT89_RS15730	COG2095	MarC family integral membrane protein
PBT89_RS15740	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PBT89_RS15750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PBT89_RS15755	COG0590	tRNA wobble adenosine to inosine editing
PBT89_RS15795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBT89_RS15800	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PBT89_RS15805	COG3720	iron ion transport
PBT89_RS15830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PBT89_RS15835	COG0626	cystathionine gamma-synthase activity
PBT89_RS15860	COG0429	hydrolase of the alpha beta-hydrolase fold
PBT89_RS15865	COG1561	YicC-like family, N-terminal region
PBT89_RS15870	COG0194	GDP metabolic process
PBT89_RS15875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PBT89_RS15880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PBT89_RS15895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PBT89_RS15915	COG0288	reversible hydration of carbon dioxide
PBT89_RS15920	COG0659	secondary active sulfate transmembrane transporter activity
PBT89_RS15945	COG2304	oxidoreductase activity
PBT89_RS15950	COG2304	oxidoreductase activity
PBT89_RS15965	COG0714	Associated with various cellular activities
PBT89_RS15975	COG4221	oxidoreductase activity
PBT89_RS15985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PBT89_RS15995	COG3339	Conserved Protein
PBT89_RS16020	COG3279	Response regulator of the LytR AlgR family
PBT89_RS16025	COG2824	Alkylphosphonate utilization operon protein PhnA
PBT89_RS16060	COG1446	asparaginase
PBT89_RS16075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT89_RS16090	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PBT89_RS16100	COG2954	triphosphatase activity
PBT89_RS16110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PBT89_RS16115	COG0469	pyruvate kinase activity
PBT89_RS16125	COG0571	ribonuclease III activity
PBT89_RS16130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBT89_RS16135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PBT89_RS16145	COG0328	RNA-DNA hybrid ribonuclease activity
PBT89_RS16165	COG1074	ATP-dependent DNA helicase activity
PBT89_RS16205	COG0534	Mate efflux family protein
PBT89_RS16240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PBT89_RS16245	COG2022	thiamine diphosphate biosynthetic process
PBT89_RS16250	COG0352	thiamine-phosphate diphosphorylase activity
PBT89_RS16260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PBT89_RS16270	COG0720	synthase
PBT89_RS16275	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT89_RS16285	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PBT89_RS16285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PBT89_RS16295	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PBT89_RS16315	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PBT89_RS16325	COG1435	thymidine kinase activity
PBT89_RS16330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PBT89_RS16335	COG1970	mechanosensitive ion channel activity
PBT89_RS16340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PBT89_RS16345	COG1505	serine-type exopeptidase activity
PBT89_RS16350	COG3842	ATPase activity
PBT89_RS16365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PBT89_RS16375	COG0439	Biotin carboxylase
PBT89_RS16380	COG0511	ligase activity, forming carbon-carbon bonds
PBT89_RS16385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBT89_RS16390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PBT89_RS16400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PBT89_RS16430	COG1136	(ABC) transporter
PBT89_RS16435	COG1136	(ABC) transporter
PBT89_RS16435	COG0577	efflux transmembrane transporter activity
PBT89_RS16440	COG1136	(ABC) transporter
PBT89_RS16440	COG0577	efflux transmembrane transporter activity
PBT89_RS16450	COG0577	efflux transmembrane transporter activity
PBT89_RS16455	COG0577	efflux transmembrane transporter activity
PBT89_RS16460	COG0577	efflux transmembrane transporter activity
PBT89_RS16460	COG1136	(ABC) transporter
PBT89_RS16470	COG0577	efflux transmembrane transporter activity
PBT89_RS16475	COG0577	efflux transmembrane transporter activity
PBT89_RS16475	COG1136	(ABC) transporter
PBT89_RS16485	COG0519	Catalyzes the synthesis of GMP from XMP
PBT89_RS16490	COG3250	beta-galactosidase activity
PBT89_RS16520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PBT89_RS16525	COG2972	Histidine kinase
PBT89_RS16530	COG3279	Response regulator of the LytR AlgR family
PBT89_RS16560	COG1194	a g-specific adenine glycosylase
PBT89_RS16595	COG5002	protein histidine kinase activity
PBT89_RS16615	COG4771	TonB-dependent receptor
PBT89_RS16695	COG0346	lactoylglutathione lyase activity
PBT89_RS16700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PBT89_RS16705	COG4591	ABC-type transport system involved in lipoprotein release permease component
PBT89_RS16720	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT89_RS16730	COG0363	glucosamine-6-phosphate deaminase activity
PBT89_RS16740	COG1629	transport
PBT89_RS16740	COG4206	TonB-dependent receptor
PBT89_RS16745	COG0405	Gamma-glutamyltransferase
PBT89_RS16750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PBT89_RS16755	COG0791	NLP P60 protein
PBT89_RS16760	COG4948	Mandelate Racemase Muconate Lactonizing
PBT89_RS16765	COG1649	PFAM Uncharacterised BCR, COG1649
PBT89_RS16775	COG1629	transport
PBT89_RS16780	COG1349	DNA-binding transcription factor activity
PBT89_RS16785	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PBT89_RS16790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PBT89_RS16800	COG0481	GTPase activity
PBT89_RS16805	COG0217	transcriptional regulatory protein