locus-tag	class	description
ZMOB_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ZMOB_RS00015	COG0488	(ABC) transporter
ZMOB_RS00020	COG2885	chlorophyll binding
ZMOB_RS00020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ZMOB_RS00025	COG4702	Belongs to the UPF0303 family
ZMOB_RS00030	COG0670	Belongs to the BI1 family
ZMOB_RS00040	COG1058	Belongs to the CinA family
ZMOB_RS00040	COG1546	Belongs to the CinA family
ZMOB_RS00045	COG0024	Methionine aminopeptidase
ZMOB_RS00060	COG0308	aminopeptidase N
ZMOB_RS00075	COG2321	neutral zinc metallopeptidase
ZMOB_RS00085	COG1280	lysine exporter protein (LysE YggA)
ZMOB_RS00090	COG1741	Belongs to the pirin family
ZMOB_RS00095	COG0583	DNA-binding transcription factor activity
ZMOB_RS00100	COG0655	NAD(P)H dehydrogenase (quinone) activity
ZMOB_RS00105	COG2353	YceI-like domain
ZMOB_RS00110	COG0668	transmembrane transport
ZMOB_RS00115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ZMOB_RS00120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ZMOB_RS00135	COG1660	Displays ATPase and GTPase activities
ZMOB_RS00140	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ZMOB_RS00145	COG0642	Histidine kinase
ZMOB_RS00150	COG0745	RESPONSE REGULATOR receiver
ZMOB_RS00160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ZMOB_RS00170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ZMOB_RS00175	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ZMOB_RS00180	COG2244	polysaccharide biosynthetic process
ZMOB_RS00190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ZMOB_RS00195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ZMOB_RS00200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ZMOB_RS00205	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ZMOB_RS00210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ZMOB_RS00220	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ZMOB_RS00220	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ZMOB_RS00225	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ZMOB_RS00240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ZMOB_RS00245	COG0321	lipoyl(octanoyl) transferase activity
ZMOB_RS00270	COG3293	Transposase
ZMOB_RS00280	COG0602	queuosine metabolic process
ZMOB_RS00285	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ZMOB_RS00295	COG2261	transglycosylase associated protein
ZMOB_RS00300	COG2223	nitrite transmembrane transporter activity
ZMOB_RS00325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ZMOB_RS00330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ZMOB_RS00335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ZMOB_RS00350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ZMOB_RS00360	COG1012	belongs to the aldehyde dehydrogenase family
ZMOB_RS00370	COG0156	8-amino-7-oxononanoate synthase activity
ZMOB_RS00390	COG3293	Transposase
ZMOB_RS00400	COG0519	Catalyzes the synthesis of GMP from XMP
ZMOB_RS00400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ZMOB_RS00410	COG4948	Mandelate Racemase Muconate Lactonizing
ZMOB_RS00415	COG1116	anion transmembrane transporter activity
ZMOB_RS00420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ZMOB_RS00435	COG4771	TonB-dependent receptor
ZMOB_RS00440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ZMOB_RS00445	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ZMOB_RS00450	COG1138	Cytochrome C-type biogenesis protein
ZMOB_RS00455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ZMOB_RS00460	COG3088	subunit of a heme lyase
ZMOB_RS00490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ZMOB_RS00500	COG2866	Carboxypeptidase
ZMOB_RS00505	COG0588	phosphoglycerate mutase activity
ZMOB_RS00510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ZMOB_RS00520	COG1064	alcohol dehydrogenase
ZMOB_RS00530	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ZMOB_RS00550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ZMOB_RS00550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ZMOB_RS00555	COG0302	gtp cyclohydrolase
ZMOB_RS00560	COG4948	Mandelate Racemase Muconate Lactonizing
ZMOB_RS00565	COG0359	binds to the 23S rRNA
ZMOB_RS00570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ZMOB_RS00575	COG0360	Binds together with S18 to 16S ribosomal RNA
ZMOB_RS00585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ZMOB_RS00600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ZMOB_RS00605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ZMOB_RS00610	COG0805	protein transport
ZMOB_RS00630	COG0513	Belongs to the DEAD box helicase family
ZMOB_RS00640	COG0166	Belongs to the GPI family
ZMOB_RS00655	COG3158	transport of potassium into the cell
ZMOB_RS00665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ZMOB_RS00685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ZMOB_RS00690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ZMOB_RS00700	COG0156	8-amino-7-oxononanoate synthase activity
ZMOB_RS00705	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ZMOB_RS00710	COG2814	Major facilitator Superfamily
ZMOB_RS00715	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ZMOB_RS00720	COG0758	DNA mediated transformation
ZMOB_RS00725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ZMOB_RS00725	COG1754	DNA topoisomerase type I activity
ZMOB_RS00730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ZMOB_RS00735	COG0756	dUTP diphosphatase activity
ZMOB_RS00740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ZMOB_RS00745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ZMOB_RS00750	COG2226	methyltransferase
ZMOB_RS00760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ZMOB_RS00785	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ZMOB_RS00800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ZMOB_RS00805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ZMOB_RS00815	COG2205	protein histidine kinase activity
ZMOB_RS00830	COG3724	N-succinylarginine dihydrolase activity
ZMOB_RS00835	COG1472	Belongs to the glycosyl hydrolase 3 family
ZMOB_RS00845	COG2971	BadF BadG BcrA BcrD
ZMOB_RS00855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ZMOB_RS00860	COG1040	competence protein
ZMOB_RS00865	COG0745	RESPONSE REGULATOR receiver
ZMOB_RS00870	COG0704	Plays a role in the regulation of phosphate uptake
ZMOB_RS00880	COG0688	phosphatidylethanolamine metabolic process
ZMOB_RS00885	COG1183	phosphatidylcholine synthase activity
ZMOB_RS00890	COG1794	racemase activity, acting on amino acids and derivatives
ZMOB_RS00900	COG0052	Belongs to the universal ribosomal protein uS2 family
ZMOB_RS00905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ZMOB_RS00910	COG0528	UMP kinase activity
ZMOB_RS00915	COG0233	cytoplasmic translational termination
ZMOB_RS00920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ZMOB_RS00925	COG0575	Belongs to the CDS family
ZMOB_RS00930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ZMOB_RS00935	COG0750	zinc metalloprotease
ZMOB_RS00940	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ZMOB_RS00950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ZMOB_RS00955	COG0254	rRNA binding
ZMOB_RS00970	COG0492	ferredoxin-NADP+ reductase activity
ZMOB_RS00975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ZMOB_RS00980	COG0440	acetolactate synthase activity
ZMOB_RS00985	COG0028	Belongs to the TPP enzyme family
ZMOB_RS00990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ZMOB_RS01000	COG1858	cytochrome C peroxidase
ZMOB_RS01005	COG0312	modulator of DNA gyrase
ZMOB_RS01015	COG0288	reversible hydration of carbon dioxide
ZMOB_RS01020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ZMOB_RS01025	COG2867	negative regulation of translational initiation
ZMOB_RS01035	COG1546	Belongs to the CinA family
ZMOB_RS01035	COG1058	Belongs to the CinA family
ZMOB_RS01045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ZMOB_RS01045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ZMOB_RS01055	COG2204	response regulator
ZMOB_RS01060	COG5000	phosphorelay sensor kinase activity
ZMOB_RS01065	COG2204	response regulator
ZMOB_RS01075	COG0776	regulation of translation
ZMOB_RS01100	COG1968	undecaprenyl-diphosphatase activity
ZMOB_RS01110	COG1573	uracil-dna glycosylase
ZMOB_RS01115	COG1252	NADH dehydrogenase
ZMOB_RS01120	COG2917	probably involved in intracellular septation
ZMOB_RS01125	COG2807	transmembrane transport
ZMOB_RS01135	COG1522	sequence-specific DNA binding
ZMOB_RS01150	COG2205	protein histidine kinase activity
ZMOB_RS01155	COG0802	atpase or kinase
ZMOB_RS01160	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ZMOB_RS01170	COG1074	ATP-dependent DNA helicase activity
ZMOB_RS01180	COG0557	exoribonuclease II activity
ZMOB_RS01185	COG3956	TIGRFAM MazG family protein
ZMOB_RS01195	COG0084	hydrolase, TatD family'
ZMOB_RS01205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ZMOB_RS01210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ZMOB_RS01215	COG1686	Belongs to the peptidase S11 family
ZMOB_RS01225	COG2951	lytic endotransglycosylase activity
ZMOB_RS01230	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ZMOB_RS01235	COG0457	Tetratricopeptide repeat
ZMOB_RS01240	COG1215	transferase activity, transferring glycosyl groups
ZMOB_RS01245	COG1215	transferase activity, transferring glycosyl groups
ZMOB_RS01260	COG0335	large ribosomal subunit rRNA binding
ZMOB_RS01265	COG0336	Belongs to the RNA methyltransferase TrmD family
ZMOB_RS01270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ZMOB_RS01275	COG0228	four-way junction DNA binding
ZMOB_RS01280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ZMOB_RS01285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ZMOB_RS01290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ZMOB_RS01295	COG0552	protein localization to endoplasmic reticulum
ZMOB_RS01305	COG0484	heat shock protein binding
ZMOB_RS01335	COG1842	Phage shock protein A
ZMOB_RS01345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ZMOB_RS01365	COG0617	tRNA 3'-terminal CCA addition
ZMOB_RS01370	COG5001	Diguanylate cyclase
ZMOB_RS01375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ZMOB_RS01390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ZMOB_RS01395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ZMOB_RS01400	COG0581	inorganic phosphate transmembrane transporter activity
ZMOB_RS01405	COG0573	inorganic phosphate transmembrane transporter activity
ZMOB_RS01410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ZMOB_RS01420	COG1970	mechanosensitive ion channel activity
ZMOB_RS01430	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ZMOB_RS01450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ZMOB_RS01460	COG0137	argininosuccinate synthase activity
ZMOB_RS01470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ZMOB_RS01475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ZMOB_RS01505	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ZMOB_RS01510	COG1104	cysteine desulfurase activity
ZMOB_RS01515	COG2945	thiolester hydrolase activity
ZMOB_RS01520	COG0019	diaminopimelate decarboxylase activity
ZMOB_RS01530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ZMOB_RS01535	COG1127	ABC transporter
ZMOB_RS01550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ZMOB_RS01555	COG0424	maF-like protein
ZMOB_RS01565	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ZMOB_RS01585	COG0277	FAD linked oxidase domain protein
ZMOB_RS01590	COG3781	membrane
ZMOB_RS01595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ZMOB_RS01605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ZMOB_RS01610	COG0351	phosphomethylpyrimidine kinase
ZMOB_RS01610	COG0352	thiamine-phosphate diphosphorylase activity
ZMOB_RS01615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ZMOB_RS01620	COG3104	oligopeptide transport
ZMOB_RS01625	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ZMOB_RS01630	COG0009	L-threonylcarbamoyladenylate synthase
ZMOB_RS01635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ZMOB_RS01640	COG0800	Aldolase
ZMOB_RS01645	COG0668	transmembrane transport
ZMOB_RS01660	COG0071	Belongs to the small heat shock protein (HSP20) family
ZMOB_RS01675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ZMOB_RS01680	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ZMOB_RS01695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ZMOB_RS01700	COG4172	Belongs to the ABC transporter superfamily
ZMOB_RS01710	COG4206	TonB-dependent receptor
ZMOB_RS01720	COG0667	Aldo Keto reductase
ZMOB_RS01750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ZMOB_RS01760	COG2252	PERMEase
ZMOB_RS01770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ZMOB_RS01775	COG2814	Major facilitator Superfamily
ZMOB_RS01780	COG1566	PFAM secretion protein HlyD family protein
ZMOB_RS01790	COG1309	transcriptional regulator
ZMOB_RS01795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ZMOB_RS01810	COG2857	Cytochrome c1
ZMOB_RS01815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ZMOB_RS01820	COG0723	plastoquinol--plastocyanin reductase activity
ZMOB_RS01825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ZMOB_RS01830	COG0408	coproporphyrinogen oxidase activity
ZMOB_RS01840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ZMOB_RS01845	COG0740	serine-type endopeptidase activity
ZMOB_RS01855	COG0544	peptidyl-prolyl cis-trans isomerase activity
ZMOB_RS01875	COG1621	beta-fructofuranosidase activity
ZMOB_RS01890	COG1846	Transcriptional regulator
ZMOB_RS01895	COG0402	S-adenosylhomocysteine deaminase activity
ZMOB_RS01900	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
ZMOB_RS01905	COG1448	Aminotransferase
ZMOB_RS01910	COG0697	spore germination
ZMOB_RS01940	COG3191	aminopeptidase activity
ZMOB_RS01945	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ZMOB_RS01955	COG1278	Cold shock
ZMOB_RS01960	COG0653	protein targeting
ZMOB_RS01965	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ZMOB_RS01990	COG3293	Transposase
ZMOB_RS02000	COG2205	protein histidine kinase activity
ZMOB_RS02000	COG0745	RESPONSE REGULATOR receiver
ZMOB_RS02000	COG3292	Two component regulator propeller
ZMOB_RS02020	COG2217	Heavy metal translocating P-type atpase
ZMOB_RS02025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ZMOB_RS02030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ZMOB_RS02070	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ZMOB_RS02080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ZMOB_RS02095	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ZMOB_RS02095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ZMOB_RS02130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ZMOB_RS02130	COG1199	ATP-dependent helicase activity
ZMOB_RS02135	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ZMOB_RS02160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ZMOB_RS02165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ZMOB_RS02170	COG0840	transmembrane signaling receptor activity
ZMOB_RS02175	COG0643	Histidine kinase
ZMOB_RS02175	COG2198	Histidine kinase
ZMOB_RS02180	COG2201	protein-glutamate methylesterase activity
ZMOB_RS02195	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ZMOB_RS02210	COG1657	PFAM Prenyltransferase squalene oxidase
ZMOB_RS02215	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ZMOB_RS02220	COG1562	ergosterol biosynthetic process
ZMOB_RS02225	COG1562	ergosterol biosynthetic process
ZMOB_RS02230	COG1215	transferase activity, transferring glycosyl groups
ZMOB_RS02235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ZMOB_RS02245	COG0305	Participates in initiation and elongation during chromosome replication
ZMOB_RS02250	COG0295	cytidine deaminase activity
ZMOB_RS02255	COG0717	Belongs to the dCTP deaminase family
ZMOB_RS02260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ZMOB_RS02265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ZMOB_RS02275	COG1104	cysteine desulfurase activity
ZMOB_RS02285	COG1722	exodeoxyribonuclease VII activity
ZMOB_RS02290	COG0142	geranyltranstransferase activity
ZMOB_RS02295	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ZMOB_RS02305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ZMOB_RS02310	COG0259	pyridoxamine-phosphate oxidase activity
ZMOB_RS02325	COG3293	Transposase
ZMOB_RS02335	COG3659	wide pore channel activity
ZMOB_RS02345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ZMOB_RS02355	COG0018	arginyl-trna synthetase
ZMOB_RS02360	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ZMOB_RS02365	COG0038	chloride channel
ZMOB_RS02375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ZMOB_RS02380	COG0849	cell division
ZMOB_RS02385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ZMOB_RS02390	COG1181	Belongs to the D-alanine--D-alanine ligase family
ZMOB_RS02395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ZMOB_RS02400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ZMOB_RS02405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ZMOB_RS02415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ZMOB_RS02420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ZMOB_RS02430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ZMOB_RS02445	COG0275	rRNA processing
ZMOB_RS02465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ZMOB_RS02470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ZMOB_RS02475	COG0720	synthase
ZMOB_RS02490	COG1322	Protein conserved in bacteria
ZMOB_RS02495	COG0242	peptide deformylase activity
ZMOB_RS02500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ZMOB_RS02505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ZMOB_RS02510	COG0101	tRNA pseudouridine synthase activity
ZMOB_RS02515	COG1872	DUF167
ZMOB_RS02520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ZMOB_RS02525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ZMOB_RS02555	COG1129	ABC transporter
ZMOB_RS02555	COG0842	Transport permease protein
ZMOB_RS02560	COG0842	Transport permease protein
ZMOB_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
ZMOB_RS02580	COG1505	serine-type exopeptidase activity
ZMOB_RS02590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ZMOB_RS02595	COG0540	Belongs to the ATCase OTCase family
ZMOB_RS02605	COG3293	Transposase
ZMOB_RS02630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ZMOB_RS02635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ZMOB_RS02640	COG0154	amidase activity
ZMOB_RS02645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ZMOB_RS02650	COG0583	DNA-binding transcription factor activity
ZMOB_RS02655	COG1538	Outer membrane efflux protein
ZMOB_RS02670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ZMOB_RS02690	COG2239	Acts as a magnesium transporter
ZMOB_RS02695	COG0482	sulfurtransferase activity
ZMOB_RS02710	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ZMOB_RS02715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ZMOB_RS02735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ZMOB_RS02760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ZMOB_RS02775	COG0564	pseudouridine synthase activity
ZMOB_RS02780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ZMOB_RS02810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ZMOB_RS02840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ZMOB_RS02850	COG2329	Antibiotic biosynthesis monooxygenase
ZMOB_RS02855	COG2022	thiamine diphosphate biosynthetic process
ZMOB_RS02860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ZMOB_RS02865	COG0511	ligase activity, forming carbon-carbon bonds
ZMOB_RS02870	COG0439	Biotin carboxylase
ZMOB_RS02885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ZMOB_RS02890	COG0085	RNA polymerase activity
ZMOB_RS02900	COG0222	ribosome binding
ZMOB_RS02905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ZMOB_RS02910	COG0081	regulation of translation
ZMOB_RS02915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ZMOB_RS02925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ZMOB_RS02935	COG3590	peptidase
ZMOB_RS02940	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ZMOB_RS02945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ZMOB_RS02950	COG0741	lytic transglycosylase activity
ZMOB_RS02960	COG2326	polyphosphate kinase activity
ZMOB_RS02965	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ZMOB_RS02970	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ZMOB_RS02975	COG0248	Ppx GppA phosphatase
ZMOB_RS02980	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ZMOB_RS02995	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ZMOB_RS03000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ZMOB_RS03005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ZMOB_RS03020	COG0318	PFAM AMP-dependent synthetase and ligase
ZMOB_RS03040	COG2076	Multidrug Resistance protein
ZMOB_RS03065	COG1764	response to oxidative stress
ZMOB_RS03070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ZMOB_RS03075	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ZMOB_RS03080	COG0673	inositol 2-dehydrogenase activity
ZMOB_RS03085	COG0679	Auxin Efflux Carrier
ZMOB_RS03100	COG3293	Transposase
ZMOB_RS03140	COG0473	3-isopropylmalate dehydrogenase activity
ZMOB_RS03150	COG0583	DNA-binding transcription factor activity
ZMOB_RS03160	COG1381	Involved in DNA repair and RecF pathway recombination
ZMOB_RS03165	COG0322	excinuclease ABC activity
ZMOB_RS03170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ZMOB_RS03175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ZMOB_RS03185	COG0356	it plays a direct role in the translocation of protons across the membrane
ZMOB_RS03210	COG2003	Belongs to the UPF0758 family
ZMOB_RS03215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ZMOB_RS03220	COG0484	heat shock protein binding
ZMOB_RS03225	COG0443	Heat shock 70 kDa protein
ZMOB_RS03260	COG0534	Mate efflux family protein
ZMOB_RS03270	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ZMOB_RS03275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ZMOB_RS03285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ZMOB_RS03290	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ZMOB_RS03305	COG0789	Transcriptional regulator
ZMOB_RS03310	COG0840	transmembrane signaling receptor activity
ZMOB_RS03320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ZMOB_RS03325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ZMOB_RS03335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ZMOB_RS03350	COG1530	ribonuclease E activity
ZMOB_RS03370	COG1760	l-serine dehydratase
ZMOB_RS03385	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ZMOB_RS03390	COG0215	cysteine-tRNA ligase activity
ZMOB_RS03400	COG0488	(ABC) transporter
ZMOB_RS03405	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ZMOB_RS03410	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ZMOB_RS03415	COG1830	Aldolase
ZMOB_RS03420	COG0126	phosphoglycerate kinase activity
ZMOB_RS03425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ZMOB_RS03450	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ZMOB_RS03460	COG0584	glycerophosphoryl diester phosphodiesterase
ZMOB_RS03465	COG2885	chlorophyll binding
ZMOB_RS03470	COG0823	Involved in the tonB-independent uptake of proteins
ZMOB_RS03480	COG0848	biopolymer transport protein
ZMOB_RS03485	COG0811	peptide transport
ZMOB_RS03490	COG0824	Thioesterase
ZMOB_RS03495	COG2255	four-way junction helicase activity
ZMOB_RS03500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ZMOB_RS03510	COG0632	four-way junction helicase activity
ZMOB_RS03515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ZMOB_RS03520	COG0217	transcriptional regulatory protein
ZMOB_RS03525	COG3750	Belongs to the UPF0335 family
ZMOB_RS03530	COG0469	pyruvate kinase activity
ZMOB_RS03540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ZMOB_RS03560	COG1131	(ABC) transporter
ZMOB_RS03575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ZMOB_RS03630	COG0671	phosphoesterase, PA-phosphatase related
ZMOB_RS03655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ZMOB_RS03670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ZMOB_RS03680	COG1151	hydroxylamine reductase activity
ZMOB_RS03685	COG1959	2 iron, 2 sulfur cluster binding
ZMOB_RS03690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ZMOB_RS03695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ZMOB_RS03695	COG0512	Glutamine amidotransferase of anthranilate synthase
ZMOB_RS03700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ZMOB_RS03715	COG0488	(ABC) transporter
ZMOB_RS03740	COG0066	3-isopropylmalate dehydratase activity
ZMOB_RS03745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ZMOB_RS03750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ZMOB_RS03775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ZMOB_RS03785	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ZMOB_RS03795	COG3293	Transposase
ZMOB_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
ZMOB_RS03820	COG0840	transmembrane signaling receptor activity
ZMOB_RS03830	COG0643	Histidine kinase
ZMOB_RS03830	COG2198	Histidine kinase
ZMOB_RS03835	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ZMOB_RS03840	COG2201	protein-glutamate methylesterase activity
ZMOB_RS03845	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ZMOB_RS03850	COG0745	RESPONSE REGULATOR receiver
ZMOB_RS03855	COG0835	chemotaxis
ZMOB_RS03860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ZMOB_RS03865	COG1702	phosphate starvation-inducible protein PhoH
ZMOB_RS03870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ZMOB_RS03885	COG2999	glutathione oxidoreductase activity
ZMOB_RS03925	COG1929	Belongs to the glycerate kinase type-1 family
ZMOB_RS03940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ZMOB_RS03945	COG0730	response to heat
ZMOB_RS03955	COG0424	maF-like protein
ZMOB_RS03965	COG0237	dephospho-CoA kinase activity
ZMOB_RS03970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ZMOB_RS03975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ZMOB_RS03980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ZMOB_RS03995	COG2983	Belongs to the UPF0260 family
ZMOB_RS04010	COG1715	Restriction endonuclease
ZMOB_RS04015	COG0138	bifunctional purine biosynthesis protein purh
ZMOB_RS04040	COG4581	dead DEAH box helicase
ZMOB_RS04045	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ZMOB_RS04050	COG1329	Transcriptional regulator
ZMOB_RS04065	COG2813	Specifically methylates the guanine in position
ZMOB_RS04065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ZMOB_RS04070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ZMOB_RS04075	COG4221	oxidoreductase activity
ZMOB_RS04080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ZMOB_RS04080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ZMOB_RS04090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ZMOB_RS04095	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ZMOB_RS04105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ZMOB_RS04120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ZMOB_RS04125	COG0489	protein tyrosine kinase activity
ZMOB_RS04135	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ZMOB_RS04140	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ZMOB_RS04145	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ZMOB_RS04150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ZMOB_RS04155	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ZMOB_RS04165	COG0776	regulation of translation
ZMOB_RS04170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ZMOB_RS04175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ZMOB_RS04180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ZMOB_RS04210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ZMOB_RS04215	COG0277	FAD linked oxidase domain protein
ZMOB_RS04230	COG4133	protoheme IX ABC transporter activity
ZMOB_RS04235	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ZMOB_RS04250	COG3293	Transposase
ZMOB_RS04265	COG3293	Transposase
ZMOB_RS04315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ZMOB_RS04320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ZMOB_RS04325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ZMOB_RS04330	COG1137	ATPase activity
ZMOB_RS04350	COG1278	Cold shock
ZMOB_RS04360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ZMOB_RS04385	COG2733	membrane
ZMOB_RS04390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ZMOB_RS04395	COG2814	Major facilitator Superfamily
ZMOB_RS04400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ZMOB_RS04405	COG0590	tRNA wobble adenosine to inosine editing
ZMOB_RS04410	COG1253	flavin adenine dinucleotide binding
ZMOB_RS04420	COG0151	Belongs to the GarS family
ZMOB_RS04425	COG1570	exodeoxyribonuclease VII activity
ZMOB_RS04440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ZMOB_RS04460	COG1028	Short-chain dehydrogenase reductase Sdr
ZMOB_RS04470	COG1473	amidohydrolase
ZMOB_RS04480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ZMOB_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
ZMOB_RS04510	COG0196	riboflavin kinase activity
ZMOB_RS04515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ZMOB_RS04520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ZMOB_RS04530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ZMOB_RS04535	COG0626	cystathionine gamma-synthase activity
ZMOB_RS04540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ZMOB_RS04545	COG0483	inositol monophosphate 1-phosphatase activity
ZMOB_RS04555	COG3108	Peptidase M15
ZMOB_RS04560	COG0352	thiamine-phosphate diphosphorylase activity
ZMOB_RS04565	COG2894	cell division
ZMOB_RS04585	COG0436	Aminotransferase
ZMOB_RS04595	COG0312	modulator of DNA gyrase
ZMOB_RS04605	COG0004	ammonium transporteR
ZMOB_RS04610	COG1923	regulation of RNA biosynthetic process
ZMOB_RS04615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ZMOB_RS04620	COG1678	Uncharacterized ACR, COG1678
ZMOB_RS04645	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ZMOB_RS04670	COG0772	Belongs to the SEDS family
ZMOB_RS04680	COG0556	nucleotide-excision repair
ZMOB_RS04690	COG0343	queuine tRNA-ribosyltransferase activity
ZMOB_RS04695	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ZMOB_RS04700	COG0477	Major facilitator Superfamily
ZMOB_RS04705	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ZMOB_RS04710	COG0129	dihydroxy-acid dehydratase activity
ZMOB_RS04715	COG0837	glucose binding
ZMOB_RS04720	COG1794	racemase activity, acting on amino acids and derivatives
ZMOB_RS04725	COG1522	sequence-specific DNA binding
ZMOB_RS04735	COG1621	beta-fructofuranosidase activity
ZMOB_RS04740	COG1621	beta-fructofuranosidase activity
ZMOB_RS04855	COG5001	Diguanylate cyclase
ZMOB_RS04860	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ZMOB_RS04865	COG0248	Ppx GppA phosphatase
ZMOB_RS04880	COG0842	Transport permease protein
ZMOB_RS04890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ZMOB_RS04895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ZMOB_RS04905	COG0187	DNA topoisomerase II activity
ZMOB_RS04910	COG2095	MarC family integral membrane protein
ZMOB_RS04925	COG2884	Cell division ATP-binding protein ftsE
ZMOB_RS04945	COG0287	Prephenate dehydrogenase
ZMOB_RS04950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ZMOB_RS04960	COG0719	Fe-S assembly protein
ZMOB_RS04965	COG0396	ATPase activity
ZMOB_RS04970	COG0719	Fe-S assembly protein
ZMOB_RS04975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ZMOB_RS04980	COG2151	metal-sulfur cluster biosynthetic enzyme
ZMOB_RS04985	COG0316	Belongs to the HesB IscA family
ZMOB_RS04995	COG2171	N-acyltransferase activity
ZMOB_RS05005	COG0194	GDP metabolic process
ZMOB_RS05040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ZMOB_RS05045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ZMOB_RS05045	COG1372	Participates in initiation and elongation during chromosome replication
ZMOB_RS05060	COG1696	Membrane protein involved in D-alanine export
ZMOB_RS05090	COG1160	GTP binding
ZMOB_RS05095	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ZMOB_RS05105	COG1522	sequence-specific DNA binding
ZMOB_RS05110	COG1136	(ABC) transporter
ZMOB_RS05120	COG0442	prolyl-tRNA aminoacylation
ZMOB_RS05125	COG0504	CTP synthase activity
ZMOB_RS05135	COG0149	triose-phosphate isomerase activity
ZMOB_RS05145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ZMOB_RS05155	COG0583	DNA-binding transcription factor activity
ZMOB_RS05165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ZMOB_RS05180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ZMOB_RS05180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ZMOB_RS05200	COG5002	protein histidine kinase activity
ZMOB_RS05210	COG1494	fructose-1,6-bisphosphatase
ZMOB_RS05225	COG1960	acyl-CoA dehydrogenase activity
ZMOB_RS05230	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ZMOB_RS05260	COG0006	proline dipeptidase activity
ZMOB_RS05265	COG0347	Belongs to the P(II) protein family
ZMOB_RS05270	COG0174	glutamine synthetase
ZMOB_RS05290	COG0546	phosphoglycolate phosphatase activity
ZMOB_RS05295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ZMOB_RS05300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ZMOB_RS05320	COG0463	Glycosyl transferase, family 2
ZMOB_RS05325	COG0564	pseudouridine synthase activity
ZMOB_RS05335	COG1956	GAF domain-containing protein
ZMOB_RS05350	COG0508	dehydrogenase complex catalyzes the overall conversion of
ZMOB_RS05355	COG1607	acyl-coa hydrolase
ZMOB_RS05360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ZMOB_RS05365	COG0671	phosphoesterase, PA-phosphatase related
ZMOB_RS05370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ZMOB_RS05375	COG0049	tRNA binding
ZMOB_RS05380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ZMOB_RS05385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ZMOB_RS05390	COG0051	transcription antitermination factor activity, RNA binding
ZMOB_RS05395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ZMOB_RS05400	COG0088	Forms part of the polypeptide exit tunnel
ZMOB_RS05405	COG0089	rRNA binding
ZMOB_RS05410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ZMOB_RS05415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ZMOB_RS05420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ZMOB_RS05425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ZMOB_RS05430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ZMOB_RS05435	COG0255	Belongs to the universal ribosomal protein uL29 family
ZMOB_RS05440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ZMOB_RS05445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ZMOB_RS05450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ZMOB_RS05455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ZMOB_RS05460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ZMOB_RS05465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ZMOB_RS05470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ZMOB_RS05475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ZMOB_RS05480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ZMOB_RS05485	COG1841	ribosomal large subunit assembly
ZMOB_RS05490	COG0200	Binds to the 23S rRNA
ZMOB_RS05495	COG0201	protein transport
ZMOB_RS05500	COG0563	adenylate kinase activity
ZMOB_RS05505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ZMOB_RS05510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ZMOB_RS05515	COG0202	RNA polymerase activity
ZMOB_RS05520	COG0203	ribosomal protein L17
ZMOB_RS05530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ZMOB_RS05535	COG0538	isocitrate dehydrogenase activity
ZMOB_RS05540	COG0134	indole-3-glycerol-phosphate synthase activity
ZMOB_RS05545	COG0659	secondary active sulfate transmembrane transporter activity
ZMOB_RS05550	COG0038	chloride channel
ZMOB_RS05560	COG1185	polyribonucleotide nucleotidyltransferase activity
ZMOB_RS05565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ZMOB_RS05570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ZMOB_RS05575	COG1435	thymidine kinase activity
ZMOB_RS05580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ZMOB_RS05585	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ZMOB_RS05585	COG3064	Membrane
ZMOB_RS05600	COG0779	Required for maturation of 30S ribosomal subunits
ZMOB_RS05605	COG2133	pyrroloquinoline quinone binding
ZMOB_RS05615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ZMOB_RS05620	COG1605	Chorismate mutase
ZMOB_RS05620	COG0287	Prephenate dehydrogenase
ZMOB_RS05625	COG0142	geranyltranstransferase activity
ZMOB_RS05630	COG1643	Atp-dependent helicase
ZMOB_RS05640	COG2814	Major facilitator Superfamily
ZMOB_RS05650	COG3293	Transposase
ZMOB_RS05670	COG2264	protein methyltransferase activity
ZMOB_RS05680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ZMOB_RS05685	COG1116	anion transmembrane transporter activity
ZMOB_RS05690	COG2999	glutathione oxidoreductase activity
ZMOB_RS05710	COG0742	ribosomal rna small subunit methyltransferase
ZMOB_RS05715	COG1187	pseudouridine synthase activity
ZMOB_RS05720	COG1301	dicarboxylic acid transport
ZMOB_RS05730	COG2223	nitrite transmembrane transporter activity
ZMOB_RS05740	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ZMOB_RS05745	COG0159	tryptophan synthase activity
ZMOB_RS05750	COG0133	tryptophan synthase activity
ZMOB_RS05755	COG0135	phosphoribosylanthranilate isomerase activity
ZMOB_RS05760	COG0284	orotidine-5'-phosphate decarboxylase activity
ZMOB_RS05775	COG1286	toxin biosynthetic process
ZMOB_RS05790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ZMOB_RS05795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ZMOB_RS05805	COG4974	Belongs to the 'phage' integrase family
ZMOB_RS05810	COG0825	malonyl-CoA metabolic process
ZMOB_RS05830	COG1360	Flagellar Motor Protein
ZMOB_RS05855	COG1706	bacterial-type flagellum-dependent cell motility
ZMOB_RS05860	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ZMOB_RS05875	COG1749	Flagellar hook protein flgE
ZMOB_RS05880	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ZMOB_RS05885	COG1558	bacterial-type flagellum-dependent cell motility
ZMOB_RS05900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ZMOB_RS05940	COG0455	bacterial-type flagellum organization
ZMOB_RS05960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ZMOB_RS05970	COG1677	Flagellar hook-basal body complex protein FliE
ZMOB_RS05980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ZMOB_RS06010	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ZMOB_RS06030	COG1987	bacterial-type flagellum assembly
ZMOB_RS06035	COG1684	flagellar biosynthetic protein fliR
ZMOB_RS06040	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ZMOB_RS06055	COG0628	permease
ZMOB_RS06060	COG0726	polysaccharide deacetylase
ZMOB_RS06075	COG3293	Transposase
ZMOB_RS06100	COG1139	Iron-sulfur cluster binding protein
ZMOB_RS06115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ZMOB_RS06125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ZMOB_RS06130	COG1420	regulation of RNA biosynthetic process
ZMOB_RS06135	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ZMOB_RS06140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ZMOB_RS06145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ZMOB_RS06165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ZMOB_RS06170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ZMOB_RS06175	COG0175	sulfate reduction
ZMOB_RS06180	COG1648	precorrin-2 dehydrogenase activity
ZMOB_RS06180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ZMOB_RS06185	COG0175	sulfate reduction
ZMOB_RS06200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ZMOB_RS06210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ZMOB_RS06220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ZMOB_RS06235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ZMOB_RS06240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ZMOB_RS06245	COG4771	TonB-dependent receptor
ZMOB_RS06250	COG0667	Aldo Keto reductase
ZMOB_RS06255	COG3386	PFAM SMP-30 Gluconolaconase
ZMOB_RS06260	COG0445	tRNA wobble uridine modification
ZMOB_RS06265	COG0357	Ribosomal RNA small subunit methyltransferase G
ZMOB_RS06280	COG0477	Major facilitator Superfamily
ZMOB_RS06295	COG0583	DNA-binding transcription factor activity
ZMOB_RS06305	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ZMOB_RS06310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ZMOB_RS06335	COG1129	ABC transporter
ZMOB_RS06350	COG2333	competence protein COMEC
ZMOB_RS06350	COG0658	competence protein
ZMOB_RS06355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ZMOB_RS06360	COG0372	Belongs to the citrate synthase family
ZMOB_RS06365	COG5002	protein histidine kinase activity
ZMOB_RS06390	COG0438	transferase activity, transferring glycosyl groups
ZMOB_RS06390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ZMOB_RS06395	COG0497	DNA recombination
ZMOB_RS06400	COG0281	malic enzyme
ZMOB_RS06405	COG0459	protein refolding
ZMOB_RS06410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ZMOB_RS06415	COG0616	signal peptide processing
ZMOB_RS06420	COG0826	peptidase U32
ZMOB_RS06430	COG1368	sulfuric ester hydrolase activity
ZMOB_RS06460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ZMOB_RS06465	COG0156	8-amino-7-oxononanoate synthase activity
ZMOB_RS06475	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ZMOB_RS06475	COG4106	trans-aconitate 2-methyltransferase activity
ZMOB_RS06485	COG0189	ligase activity
ZMOB_RS06495	COG0012	GTP binding
ZMOB_RS06500	COG0193	aminoacyl-tRNA hydrolase activity
ZMOB_RS06505	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ZMOB_RS06520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ZMOB_RS06525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ZMOB_RS06530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ZMOB_RS06535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ZMOB_RS06540	COG0181	hydroxymethylbilane synthase activity
ZMOB_RS06555	COG0416	fatty acid biosynthetic process
ZMOB_RS06560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ZMOB_RS06570	COG1862	Preprotein translocase
ZMOB_RS06575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ZMOB_RS06585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ZMOB_RS06600	COG0612	Peptidase, M16
ZMOB_RS06620	COG1335	isochorismatase
ZMOB_RS06630	COG1902	pentaerythritol trinitrate reductase activity
ZMOB_RS06635	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ZMOB_RS06640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ZMOB_RS06645	COG3180	Ammonia monooxygenase
ZMOB_RS06660	COG0113	porphobilinogen synthase activity
ZMOB_RS06665	COG0525	valine-tRNA ligase activity
ZMOB_RS06690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ZMOB_RS06700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ZMOB_RS06720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ZMOB_RS06780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ZMOB_RS06785	COG0716	FMN binding
ZMOB_RS06805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ZMOB_RS06810	COG1120	ATPase activity
ZMOB_RS06815	COG2824	Alkylphosphonate utilization operon protein PhnA
ZMOB_RS06820	COG0673	inositol 2-dehydrogenase activity
ZMOB_RS06840	COG3585	molybdate ion transport
ZMOB_RS06855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ZMOB_RS06860	COG1104	cysteine desulfurase activity
ZMOB_RS06890	COG1433	Dinitrogenase iron-molybdenum cofactor
ZMOB_RS06895	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ZMOB_RS06900	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ZMOB_RS06905	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ZMOB_RS06910	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ZMOB_RS06915	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ZMOB_RS06920	COG4774	siderophore transport
ZMOB_RS06930	COG5554	nitrogen fixation
ZMOB_RS06940	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ZMOB_RS06945	COG0535	radical SAM domain protein
ZMOB_RS06965	COG4657	Part of a membrane complex involved in electron transport
ZMOB_RS06975	COG4656	Part of a membrane complex involved in electron transport
ZMOB_RS06980	COG4658	electron transport chain
ZMOB_RS07005	COG0110	maltose O-acetyltransferase activity
ZMOB_RS07010	COG0546	phosphoglycolate phosphatase activity
ZMOB_RS07015	COG0531	amino acid
ZMOB_RS07020	COG0776	regulation of translation
ZMOB_RS07030	COG0539	negative regulation of cytoplasmic translation
ZMOB_RS07035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ZMOB_RS07040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ZMOB_RS07060	COG0129	dihydroxy-acid dehydratase activity
ZMOB_RS07070	COG1132	(ABC) transporter
ZMOB_RS07080	COG3293	Transposase
ZMOB_RS07105	COG0668	transmembrane transport
ZMOB_RS07145	COG0656	L-ascorbic acid biosynthetic process
ZMOB_RS07150	COG0604	alcohol dehydrogenase
ZMOB_RS07150	COG3321	synthase
ZMOB_RS07155	COG1979	alcohol dehydrogenase
ZMOB_RS07160	COG0165	Argininosuccinate lyase
ZMOB_RS07170	COG0019	diaminopimelate decarboxylase activity
ZMOB_RS07185	COG2989	Protein conserved in bacteria
ZMOB_RS07195	COG0792	nuclease activity
ZMOB_RS07200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ZMOB_RS07210	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ZMOB_RS07215	COG3265	gluconokinase activity
ZMOB_RS07220	COG2610	gluconate transmembrane transporter activity
ZMOB_RS07225	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ZMOB_RS07230	COG1012	belongs to the aldehyde dehydrogenase family
ZMOB_RS07255	COG2853	Lipoprotein
ZMOB_RS07275	COG1410	methionine synthase
ZMOB_RS07275	COG0646	methionine synthase
ZMOB_RS07285	COG0481	GTPase activity
ZMOB_RS07295	COG3275	phosphorelay sensor kinase activity
ZMOB_RS07300	COG3279	Response regulator of the LytR AlgR family
ZMOB_RS07315	COG0583	DNA-binding transcription factor activity
ZMOB_RS07325	COG1045	serine acetyltransferase
ZMOB_RS07345	COG0436	Aminotransferase
ZMOB_RS07350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ZMOB_RS07355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ZMOB_RS07370	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ZMOB_RS07380	COG1758	RNA polymerase activity
ZMOB_RS07385	COG1940	carbohydrate kinase activity
ZMOB_RS07415	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ZMOB_RS07425	COG0628	permease
ZMOB_RS07430	COG0681	Belongs to the peptidase S26 family
ZMOB_RS07435	COG0736	holo-[acyl-carrier-protein] synthase activity
ZMOB_RS07440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ZMOB_RS07445	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ZMOB_RS07460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ZMOB_RS07465	COG1674	ftsk spoiiie
ZMOB_RS07470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ZMOB_RS07480	COG0708	Exodeoxyribonuclease III
ZMOB_RS07490	COG1733	regulation of RNA biosynthetic process
ZMOB_RS07515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ZMOB_RS07520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ZMOB_RS07525	COG1295	ribonuclease BN
ZMOB_RS07530	COG0484	heat shock protein binding
ZMOB_RS07535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ZMOB_RS07540	COG0354	folic acid binding
ZMOB_RS07545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ZMOB_RS07555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ZMOB_RS07565	COG0252	asparaginase activity
ZMOB_RS07575	COG2985	domain, Protein
ZMOB_RS07600	COG0077	Prephenate dehydratase
ZMOB_RS07605	COG1194	a g-specific adenine glycosylase
ZMOB_RS07620	COG0656	L-ascorbic acid biosynthetic process
ZMOB_RS07640	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ZMOB_RS07650	COG0793	Belongs to the peptidase S41A family
ZMOB_RS07660	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ZMOB_RS07665	COG0799	negative regulation of ribosome biogenesis
ZMOB_RS07670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ZMOB_RS07675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ZMOB_RS07690	COG0037	tRNA processing
ZMOB_RS07710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ZMOB_RS07725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ZMOB_RS07735	COG3386	PFAM SMP-30 Gluconolaconase
ZMOB_RS07745	COG3293	Transposase
ZMOB_RS07750	COG3386	PFAM SMP-30 Gluconolaconase
ZMOB_RS07755	COG1573	uracil-dna glycosylase
ZMOB_RS07770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ZMOB_RS07780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ZMOB_RS07785	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ZMOB_RS07795	COG0180	Tryptophanyl-tRNA synthetase
ZMOB_RS07800	COG0728	peptidoglycan biosynthetic process
ZMOB_RS07805	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ZMOB_RS07820	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ZMOB_RS07835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ZMOB_RS07840	COG4774	siderophore transport
ZMOB_RS07860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ZMOB_RS07865	COG0706	membrane insertase activity
ZMOB_RS07870	COG0594	ribonuclease P activity
ZMOB_RS07880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ZMOB_RS07895	COG0505	Belongs to the CarA family
ZMOB_RS07905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ZMOB_RS07940	COG0148	phosphopyruvate hydratase activity
ZMOB_RS07950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ZMOB_RS07955	COG0022	dehydrogenase e1 component
ZMOB_RS07955	COG0508	dehydrogenase complex catalyzes the overall conversion of
ZMOB_RS07965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ZMOB_RS07965	COG3453	Protein conserved in bacteria
ZMOB_RS07975	COG0328	RNA-DNA hybrid ribonuclease activity
ZMOB_RS07980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ZMOB_RS07990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ZMOB_RS07995	COG1454	alcohol dehydrogenase
ZMOB_RS08010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ZMOB_RS08015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ZMOB_RS08020	COG1127	ABC transporter
ZMOB_RS08025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ZMOB_RS08030	COG0730	response to heat
ZMOB_RS08035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ZMOB_RS08050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ZMOB_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
ZMOB_RS08115	COG4221	oxidoreductase activity
ZMOB_RS08135	COG1294	oxidase, subunit
ZMOB_RS08140	COG1271	oxidase subunit
ZMOB_RS08155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ZMOB_RS08170	COG1742	UPF0060 membrane protein
ZMOB_RS08190	COG1051	belongs to the nudix hydrolase family
ZMOB_RS08195	COG4221	oxidoreductase activity
ZMOB_RS08205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ZMOB_RS08220	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ZMOB_RS08225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ZMOB_RS08230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ZMOB_RS08235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ZMOB_RS08245	COG1657	PFAM Prenyltransferase squalene oxidase
ZMOB_RS08270	COG0629	single-stranded DNA binding
ZMOB_RS08300	COG0047	phosphoribosylformylglycinamidine synthase activity
ZMOB_RS08305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ZMOB_RS08310	COG0517	IMP dehydrogenase activity
ZMOB_RS08310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ZMOB_RS08315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ZMOB_RS08330	COG1538	Outer membrane efflux protein
ZMOB_RS08355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ZMOB_RS08365	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ZMOB_RS08370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ZMOB_RS08375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ZMOB_RS08375	COG0072	phenylalanine-tRNA ligase activity
ZMOB_RS08380	COG5265	(ABC) transporter
ZMOB_RS08390	COG2890	protein-(glutamine-N5) methyltransferase activity
ZMOB_RS08395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ZMOB_RS08400	COG0124	histidyl-tRNA synthetase
ZMOB_RS08405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ZMOB_RS08425	COG0131	Imidazoleglycerol-phosphate dehydratase
ZMOB_RS08430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ZMOB_RS08435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ZMOB_RS08440	COG0107	imidazoleglycerol-phosphate synthase activity
ZMOB_RS08445	COG0140	phosphoribosyl-ATP diphosphatase activity
ZMOB_RS08455	COG0531	amino acid
ZMOB_RS08460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ZMOB_RS08465	COG2096	Adenosyltransferase
ZMOB_RS08470	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ZMOB_RS08495	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ZMOB_RS08500	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ZMOB_RS08505	COG2199	diguanylate cyclase activity
ZMOB_RS08505	COG2200	EAL domain
ZMOB_RS08520	COG0210	DNA helicase
ZMOB_RS08535	COG0045	succinate-CoA ligase (ADP-forming) activity
ZMOB_RS08550	COG0363	glucosamine-6-phosphate deaminase activity
ZMOB_RS08570	COG1217	gtp-binding protein TYPA
ZMOB_RS08585	COG0814	amino acid
ZMOB_RS08610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ZMOB_RS08615	COG2814	Major facilitator Superfamily
ZMOB_RS08630	COG1091	dTDP-4-dehydrorhamnose reductase activity
ZMOB_RS08635	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ZMOB_RS08640	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ZMOB_RS08650	COG0415	Belongs to the DNA photolyase family
ZMOB_RS08655	COG0246	Mannitol dehydrogenase
ZMOB_RS08675	COG0752	glycyl-tRNA synthetase alpha subunit
ZMOB_RS08685	COG2244	polysaccharide biosynthetic process
ZMOB_RS08705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ZMOB_RS08725	COG0495	leucyl-tRNA aminoacylation
ZMOB_RS08760	COG1597	lipid kinase activity
ZMOB_RS08765	COG2003	Belongs to the UPF0758 family
ZMOB_RS08770	COG0352	thiamine-phosphate diphosphorylase activity
ZMOB_RS08780	COG0612	Peptidase, M16
ZMOB_RS08785	COG0612	Peptidase, M16
ZMOB_RS08790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ZMOB_RS08795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ZMOB_RS08800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ZMOB_RS08810	COG0513	Belongs to the DEAD box helicase family
ZMOB_RS08825	COG1214	PFAM Peptidase M22, glycoprotease
ZMOB_RS08835	COG4957	zinc ion binding
ZMOB_RS08845	COG2193	ferroxidase activity
ZMOB_RS08865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ZMOB_RS08870	COG0596	Alpha beta hydrolase
ZMOB_RS08875	COG0784	Response regulator, receiver
ZMOB_RS08885	COG0739	heme binding
ZMOB_RS08890	COG0316	Belongs to the HesB IscA family
ZMOB_RS08895	COG0708	Exodeoxyribonuclease III
ZMOB_RS08955	COG0405	Gamma-glutamyltransferase
ZMOB_RS08975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ZMOB_RS08980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ZMOB_RS09010	COG0571	ribonuclease III activity
ZMOB_RS09020	COG0300	oxidoreductase activity
ZMOB_RS09040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ZMOB_RS09050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ZMOB_RS09070	COG3961	Belongs to the TPP enzyme family
ZMOB_RS09075	COG0268	Binds directly to 16S ribosomal RNA
ZMOB_RS09680	COG0438	transferase activity, transferring glycosyl groups
ZMOB_RS09680	COG1216	Glycosyl transferase, family 2
ZMOB_RS09685	COG1216	Glycosyl transferase, family 2