locus-tag	class	description
AZF37_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AZF37_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AZF37_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AZF37_RS00020	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AZF37_RS00025	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AZF37_RS00035	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AZF37_RS00040	ENOG4105BZU	Histidine kinase
AZF37_RS00100	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AZF37_RS00105	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AZF37_RS00110	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AZF37_RS00115	ENOG4107WAU	Protein tyrosine phosphatase
AZF37_RS00125	ENOG4108YZG	isomerase
AZF37_RS00130	ENOG4108UK2	deaminase
AZF37_RS00135	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AZF37_RS00145	ENOG4105CH7	arginosuccinase
AZF37_RS00150	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AZF37_RS00155	ENOG4108KGH	TRANSCRIPTIONal
AZF37_RS00165	ENOG4105E3H	phosphoglycerate mutase
AZF37_RS00180	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AZF37_RS00185	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AZF37_RS00200	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AZF37_RS00235	ENOG4108JJB	ABC transporter
AZF37_RS00240	ENOG4108JJB	ABC transporter
AZF37_RS00285	ENOG4105CJ1	ABC, transporter
AZF37_RS00290	ENOG4105CJ1	ABC, transporter
AZF37_RS00295	ENOG4105WH1	Two component transcriptional regulator luxr family
AZF37_RS00315	ENOG4105CMR	udp-glucose 4-epimerase
AZF37_RS00320	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AZF37_RS00345	ENOG4105CRK	lysyL-tRNA synthetase
AZF37_RS00350	ENOG4105C37	(CBS) domain
AZF37_RS00355	ENOG4107R73	Mate efflux family protein
AZF37_RS00365	ENOG4105C87	Aminotransferase class I and II
AZF37_RS00395	ENOG4105CHR	reductase
AZF37_RS00410	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
AZF37_RS00425	ENOG4105UIB	(ABC) transporter
AZF37_RS00435	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AZF37_RS00450	ENOG4108JQ9	ABC transporter
AZF37_RS00490	ENOG4105DQ6	Transposase
AZF37_RS00560	ENOG4108IG5	Transcriptional regulator
AZF37_RS00630	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AZF37_RS00685	ENOG4108JJB	ABC transporter
AZF37_RS00690	ENOG4108JJB	ABC transporter
AZF37_RS00695	ENOG4108JJB	ABC transporter
AZF37_RS00715	ENOG4108TGC	Acyltransferase
AZF37_RS00735	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AZF37_RS00760	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AZF37_RS00770	ENOG4105D49	3-dehydroquinate synthase
AZF37_RS00775	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AZF37_RS00780	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AZF37_RS00785	ENOG4105CQC	Prephenate dehydratase
AZF37_RS00795	ENOG4105DUM	transcriptional regulator, lysR family
AZF37_RS00815	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
AZF37_RS00865	ENOG4105CHR	reductase
AZF37_RS00870	ENOG4105EMU	Dehydrogenase
AZF37_RS00875	ENOG4105CHR	reductase
AZF37_RS00910	ENOG4105CN1	protease
AZF37_RS00915	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AZF37_RS00930	ENOG4105JVQ	RNA Polymerase
AZF37_RS01085	ENOG4105K64	Glycosyl transferase, family 2
AZF37_RS01090	ENOG4107R6R	udp-galactopyranose mutase
AZF37_RS01120	ENOG4105KBX	Transcriptional regulator, TetR family
AZF37_RS01155	ENOG4108RSN	SNARE associated Golgi
AZF37_RS01160	ENOG4107QR9	Iron-sulfur cluster binding protein
AZF37_RS01185	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AZF37_RS01190	ENOG4107VMI	polysaccharide deacetylase
AZF37_RS01225	ENOG4105KVH	Transcriptional regulator
AZF37_RS01240	ENOG4108Z6Z	Transcriptional regulator
AZF37_RS01300	ENOG4107S4Y	M20 DapE family protein YgeY
AZF37_RS01330	ENOG4105CI3	gtp-binding protein typa
AZF37_RS01335	ENOG4108UQ1	hydrolase, family 25
AZF37_RS01350	ENOG4105C1J	atp-dependent rna helicase
AZF37_RS01355	ENOG410838F	Glycosyl transferase family 2
AZF37_RS01490	ENOG4108V8F	Transcriptional regulator, MarR family
AZF37_RS01530	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AZF37_RS01570	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AZF37_RS01585	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AZF37_RS01590	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AZF37_RS01630	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AZF37_RS01640	ENOG4105C7K	acetolactate synthase
AZF37_RS01650	ENOG4105C7K	acetolactate synthase
AZF37_RS01655	ENOG4105C7K	acetolactate synthase
AZF37_RS01715	ENOG4108UQ1	hydrolase, family 25
AZF37_RS01735	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AZF37_RS01740	ENOG4105EHG	Permease protein
AZF37_RS01760	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AZF37_RS01790	ENOG4105CEN	a g-specific adenine glycosylase
AZF37_RS01810	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZF37_RS01815	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZF37_RS01860	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AZF37_RS01870	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AZF37_RS01885	ENOG4105ESV	Glycosyl transferase, family 4
AZF37_RS01890	ENOG4105CEV	competence damage-inducible protein
AZF37_RS01895	ENOG4105CEV	competence damage-inducible protein
AZF37_RS01900	ENOG4107QUY	Guanine deaminase
AZF37_RS01905	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AZF37_RS01910	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AZF37_RS01915	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AZF37_RS01920	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AZF37_RS01925	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AZF37_RS01930	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AZF37_RS01945	ENOG4105KHC	sulfurtransferase
AZF37_RS01955	ENOG4105WH5	Teichoic acid glycosylation protein
AZF37_RS01960	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AZF37_RS01965	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
AZF37_RS01970	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
AZF37_RS01980	ENOG4105CUZ	uba thif-type nad fad binding protein
AZF37_RS02000	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AZF37_RS02010	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AZF37_RS02015	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AZF37_RS02025	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AZF37_RS02030	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AZF37_RS02045	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AZF37_RS02050	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AZF37_RS02060	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AZF37_RS02065	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AZF37_RS02090	ENOG4105BZ1	(ABC) transporter
AZF37_RS02105	ENOG4105CCI	Myosin-Cross-Reactive Antigen
AZF37_RS02125	ENOG4108JJB	ABC transporter
AZF37_RS02140	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AZF37_RS02200	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
AZF37_RS02225	ENOG4105E90	ABC transporter
AZF37_RS02260	ENOG4105D98	threonine synthase
AZF37_RS02265	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AZF37_RS02270	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AZF37_RS02300	ENOG4105EGD	dinuclear metal center protein, YbgI family
AZF37_RS02305	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
AZF37_RS02315	ENOG4105CE9	30S ribosomal protein S2
AZF37_RS02320	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AZF37_RS02330	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AZF37_RS02340	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AZF37_RS02345	ENOG4105KNE	Phosphatidate cytidylyltransferase
AZF37_RS02350	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AZF37_RS02355	ENOG4105DZP	Membrane-associated zinc metalloprotease
AZF37_RS02360	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AZF37_RS02365	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AZF37_RS02370	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AZF37_RS02380	ENOG4105C6K	Malic enzyme
AZF37_RS02390	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AZF37_RS02420	ENOG4105CJN	penicillin-binding protein
AZF37_RS02425	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AZF37_RS02430	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AZF37_RS02435	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AZF37_RS02440	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AZF37_RS02445	ENOG4105CNI	cell division protein FtsW
AZF37_RS02450	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AZF37_RS02455	ENOG4105DFU	Cell wall formation (By similarity)
AZF37_RS02460	ENOG4105D4A	Cell wall formation (By similarity)
AZF37_RS02465	ENOG4105ME9	cell division protein FtsQ
AZF37_RS02470	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AZF37_RS02490	ENOG4105DFA	alanine racemase domain protein
AZF37_RS02495	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AZF37_RS02505	ENOG4105DBK	s4 domain protein
AZF37_RS02510	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AZF37_RS02515	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
AZF37_RS02520	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AZF37_RS02525	ENOG4105C34	Pseudouridine synthase
AZF37_RS02530	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AZF37_RS02570	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AZF37_RS02575	ENOG4105K63	Thioredoxin
AZF37_RS02580	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AZF37_RS02585	ENOG4105CXT	aspartate transcarbamylase
AZF37_RS02590	ENOG4105CD3	dihydroorotase
AZF37_RS02595	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
AZF37_RS02600	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AZF37_RS02605	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AZF37_RS02610	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AZF37_RS02640	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
AZF37_RS02650	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AZF37_RS02655	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AZF37_RS02660	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AZF37_RS02665	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AZF37_RS02675	ENOG410823V	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AZF37_RS02695	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AZF37_RS02700	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AZF37_RS02705	ENOG4107BJW	polysaccharide deacetylase
AZF37_RS02715	ENOG4105VCQ	rubredoxin
AZF37_RS02805	ENOG4105VC4	domain protein
AZF37_RS02875	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
AZF37_RS02880	ENOG4105F1A	Pyruvate formate-lyase
AZF37_RS02895	ENOG4107QZB	decarboxylase
AZF37_RS02935	ENOG4105EPR	degv family
AZF37_RS02940	ENOG4105EPR	degv family
AZF37_RS02960	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AZF37_RS03050	ENOG4105GD4	(Histidine triad) protein
AZF37_RS03055	ENOG4105YB8	TM2 domain containing protein
AZF37_RS03110	ENOG4105FDK	ABC transporter
AZF37_RS03125	ENOG4108V2W	Carbonate dehydratase
AZF37_RS03130	ENOG4108REF	Sporulation integral membrane protein ytvi
AZF37_RS03155	ENOG4105CE1	Ferrous iron transport protein b
AZF37_RS03200	ENOG4105C2W	permease
AZF37_RS03205	ENOG4107S4Y	M20 DapE family protein YgeY
AZF37_RS03210	ENOG4105DBV	ornithine carbamoyltransferase
AZF37_RS03215	ENOG4105BZ8	glutamate synthase
AZF37_RS03220	ENOG4107UUR	Chlorohydrolase aminohydrolase
AZF37_RS03235	ENOG4108UTP	(2Fe-2S)-binding domain protein
AZF37_RS03255	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AZF37_RS03270	ENOG4105WDJ	50S ribosomal protein L33
AZF37_RS03280	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AZF37_RS03285	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AZF37_RS03295	ENOG4108VZM	50s ribosomal protein L10
AZF37_RS03300	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AZF37_RS03310	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AZF37_RS03315	ENOG4105XPM	ribosomal protein
AZF37_RS03320	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AZF37_RS03325	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AZF37_RS03330	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AZF37_RS03335	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AZF37_RS03340	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AZF37_RS03345	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AZF37_RS03350	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AZF37_RS03355	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AZF37_RS03360	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZF37_RS03365	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AZF37_RS03370	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AZF37_RS03375	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AZF37_RS03380	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AZF37_RS03385	ENOG41082SA	50s ribosomal protein l29
AZF37_RS03395	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AZF37_RS03400	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AZF37_RS03415	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AZF37_RS03420	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AZF37_RS03425	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AZF37_RS03430	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AZF37_RS03435	ENOG4105VPB	50S ribosomal protein L30
AZF37_RS03440	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AZF37_RS03445	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AZF37_RS03455	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AZF37_RS03460	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AZF37_RS03465	ENOG41067V7	50S ribosomal protein L36
AZF37_RS03470	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZF37_RS03475	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AZF37_RS03480	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AZF37_RS03490	ENOG4108ZT0	50S ribosomal protein l17
AZF37_RS03540	ENOG4105DCT	glycerol dehydrogenase
AZF37_RS03630	ENOG4105DQ6	Transposase
AZF37_RS03650	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AZF37_RS03675	ENOG4105C1A	potassium transporter peripheral membrane
AZF37_RS03710	ENOG4108UZE	carboxy-peptidase
AZF37_RS03735	ENOG4105DGN	Electron transport complex
AZF37_RS03740	ENOG4105DZB	Electron transport complex
AZF37_RS03745	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
AZF37_RS03750	ENOG4105D6A	Electron transport complex
AZF37_RS03755	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
AZF37_RS03760	ENOG4105C3G	gtp-binding protein
AZF37_RS03775	ENOG4105C79	DNA protecting protein DprA
AZF37_RS03780	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AZF37_RS03790	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AZF37_RS03795	ENOG4105CHV	Transcription elongation factor NusA
AZF37_RS03800	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AZF37_RS03810	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AZF37_RS03810	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AZF37_RS03815	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AZF37_RS03820	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AZF37_RS03825	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AZF37_RS03830	ENOG4105DTN	riboflavin biosynthesis protein ribF
AZF37_RS03845	ENOG4105D5T	phosphonate abc transporter
AZF37_RS03850	ENOG4105CAK	Cell division ATP-binding protein ftsE
AZF37_RS03855	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AZF37_RS03875	ENOG4105VB9	50S ribosomal protein l28
AZF37_RS03880	ENOG4108ZAA	Alkaline-shock protein
AZF37_RS03885	ENOG4105DP4	dak2 domain fusion protein ylov
AZF37_RS03890	ENOG4105C1V	Peptidase, M16
AZF37_RS03895	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AZF37_RS03915	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AZF37_RS03920	ENOG4108RWN	rrna methyltransferase
AZF37_RS03940	ENOG4105BZA	Phosphoglycerate kinase
AZF37_RS03950	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AZF37_RS03955	ENOG4105XZU	Preprotein translocase, subunit SecG
AZF37_RS03960	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AZF37_RS03965	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AZF37_RS03975	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AZF37_RS03980	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AZF37_RS03995	ENOG4105UQX	Mate efflux family protein
AZF37_RS04035	ENOG4105EAB	amino acid AbC transporter
AZF37_RS04045	ENOG4105CDA	abc transporter atp-binding protein
AZF37_RS04055	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AZF37_RS04060	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AZF37_RS04065	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AZF37_RS04070	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AZF37_RS04075	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AZF37_RS04080	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AZF37_RS04085	ENOG4105CSA	Coproporphyrinogen iii oxidase
AZF37_RS04090	ENOG4105CIZ	coA-substrate-specific enzyme activase
AZF37_RS04100	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AZF37_RS04155	ENOG4107QSA	Oxaloacetate decarboxylase
AZF37_RS04160	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AZF37_RS04235	ENOG4105G5W	regulator Fur family
AZF37_RS04245	ENOG4105FDK	ABC transporter
AZF37_RS04315	ENOG4108IJ8	ABC transporter
AZF37_RS04335	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AZF37_RS04340	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AZF37_RS04350	ENOG4105C7H	Helicase, RecD TraA family
AZF37_RS04355	ENOG4105C8J	)-transporter
AZF37_RS04380	ENOG4105DSJ	YicC domain protein
AZF37_RS04385	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AZF37_RS04400	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AZF37_RS04420	ENOG4105CFP	Peptidase U32
AZF37_RS04425	ENOG4105XYU	peptidase (U32 family)
AZF37_RS04460	ENOG4105C98	muts2 protein
AZF37_RS04475	ENOG4105C98	muts2 protein
AZF37_RS04480	ENOG4105EQI	Metal Dependent Phosphohydrolase
AZF37_RS04485	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AZF37_RS04495	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AZF37_RS04510	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
AZF37_RS04520	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
AZF37_RS04525	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AZF37_RS04530	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AZF37_RS04535	ENOG4108V0P	LemA family
AZF37_RS04565	ENOG4108UQV	Membrane
AZF37_RS04575	ENOG4105C25	Primosomal protein n'
AZF37_RS04580	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AZF37_RS04585	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AZF37_RS04600	ENOG4108ZF3	Phosphatase
AZF37_RS04605	ENOG4105D9P	serine threonine protein kinase
AZF37_RS04610	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AZF37_RS04615	ENOG4105DJV	ribulose-phosphate 3-epimerase
AZF37_RS04625	ENOG4107TB6	phosphoglycerate mutase
AZF37_RS04635	ENOG4106H78	methyltransferase
AZF37_RS04645	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AZF37_RS04660	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AZF37_RS04670	ENOG4105CJ1	ABC, transporter
AZF37_RS04695	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AZF37_RS04700	ENOG4108N5C	SNARE associated Golgi protein-related protein
AZF37_RS04720	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AZF37_RS04725	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AZF37_RS04745	ENOG4105CNU	cell division protein FtsK
AZF37_RS04750	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
AZF37_RS04765	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AZF37_RS04775	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AZF37_RS04785	ENOG4105C31	Tryptophanyl-tRNA synthetase
AZF37_RS04790	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AZF37_RS04795	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AZF37_RS04800	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AZF37_RS04850	ENOG4105D6E	homoserine dehydrogenase
AZF37_RS04860	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AZF37_RS04900	ENOG4105K5M	30s ribosomal protein S16
AZF37_RS04910	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AZF37_RS04915	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AZF37_RS04920	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AZF37_RS04930	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AZF37_RS04935	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AZF37_RS04940	ENOG4105FE9	pseudouridine synthase
AZF37_RS04950	ENOG4105CBX	hi0933 family
AZF37_RS04960	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AZF37_RS04980	ENOG4105CPF	Cell wall formation (By similarity)
AZF37_RS05005	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AZF37_RS05010	ENOG4105CXI	aluminum resistance protein
AZF37_RS05015	ENOG41067MG	lrgb family
AZF37_RS05020	ENOG41083D3	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses (By similarity)
AZF37_RS05030	ENOG4108UMI	ABC transporter, permease
AZF37_RS05035	ENOG4105D01	(LipO)protein
AZF37_RS05070	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AZF37_RS05080	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AZF37_RS05090	ENOG4105D1H	recombination factor protein RarA
AZF37_RS05095	ENOG4105C9M	aspartyl-trna synthetase
AZF37_RS05100	ENOG4105CUT	histidyl-tRNA synthetase
AZF37_RS05105	ENOG4105C5X	domain protein
AZF37_RS05115	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AZF37_RS05120	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AZF37_RS05125	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AZF37_RS05135	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AZF37_RS05155	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AZF37_RS05160	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AZF37_RS05200	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AZF37_RS05205	ENOG4105KG3	cytidine deaminase
AZF37_RS05230	ENOG4105CX6	glutaminyL-tRNA synthetase
AZF37_RS05235	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AZF37_RS05240	ENOG4107YU2	histidine triad (hIT) protein
AZF37_RS05245	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AZF37_RS05250	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AZF37_RS05255	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AZF37_RS05270	ENOG4107SUZ	Sodium/hydrogen exchanger family
AZF37_RS05275	ENOG4107SUZ	Sodium/hydrogen exchanger family
AZF37_RS05280	ENOG4105EEQ	Na H antiporter
AZF37_RS05305	ENOG4108JJB	ABC transporter
AZF37_RS05310	ENOG4108JJB	ABC transporter
AZF37_RS05315	ENOG4108JJB	ABC transporter
AZF37_RS05330	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AZF37_RS05335	ENOG4105CFG	Acts as a chaperone (By similarity)
AZF37_RS05340	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZF37_RS05345	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AZF37_RS05375	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AZF37_RS05385	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AZF37_RS05415	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AZF37_RS05420	ENOG4105KGF	protein, YerC YecD
AZF37_RS05430	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AZF37_RS05440	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AZF37_RS05455	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AZF37_RS05470	ENOG4105CJ3	phosphate transporter
AZF37_RS05475	ENOG4105C5H	ABC transporter
AZF37_RS05500	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AZF37_RS05535	ENOG4105CN5	Metallo-Beta-Lactamase
AZF37_RS05580	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AZF37_RS05585	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AZF37_RS05590	ENOG4105CYW	agmatinase
AZF37_RS05595	ENOG4105CXN	decarboxylase
AZF37_RS05600	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AZF37_RS05605	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AZF37_RS05615	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AZF37_RS05620	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AZF37_RS05640	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AZF37_RS05655	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AZF37_RS05660	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AZF37_RS05665	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AZF37_RS05675	ENOG4105DQR	SNARE associated Golgi
AZF37_RS05680	ENOG4105CTB	Polyprenyl synthetase
AZF37_RS05690	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AZF37_RS05700	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AZF37_RS05705	ENOG4105BZ8	glutamate synthase
AZF37_RS05710	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
AZF37_RS05725	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AZF37_RS05730	ENOG4105DC7	peptidase M24
AZF37_RS05740	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AZF37_RS05745	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AZF37_RS05750	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AZF37_RS05760	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AZF37_RS05765	ENOG4105CFP	Peptidase U32
AZF37_RS05775	ENOG41085AS	UPF0473 protein
AZF37_RS05785	ENOG4105VBH	UPF0297 protein
AZF37_RS05790	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AZF37_RS05795	ENOG4105MCT	stage V sporulation protein S
AZF37_RS05800	ENOG4105D48	metallophosphoesterase
AZF37_RS05805	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AZF37_RS05810	ENOG410691R	Modulates RecA activity (By similarity)
AZF37_RS05825	ENOG4105DZC	cytosine deaminase
AZF37_RS05840	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
AZF37_RS05875	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AZF37_RS05885	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AZF37_RS05890	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AZF37_RS05895	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AZF37_RS05905	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZF37_RS05910	ENOG4105K46	50S ribosomal protein l27
AZF37_RS05955	ENOG4105CNI	cell division protein FtsW
AZF37_RS05975	ENOG4105DFF	Rod shape-determining protein mreb
AZF37_RS05980	ENOG4105W5Q	DNA repair protein (RadC
AZF37_RS05985	ENOG4105W5Q	DNA repair protein (RadC
AZF37_RS06005	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AZF37_RS06010	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AZF37_RS06040	ENOG4107QYV	phosphohexose isomerase
AZF37_RS06050	ENOG4108NJY	Repeat protein
AZF37_RS06080	ENOG4105BZU	Histidine kinase
AZF37_RS06085	ENOG4105BZU	Histidine kinase
AZF37_RS06135	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AZF37_RS06140	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AZF37_RS06160	ENOG4105CHM	Aminotransferase
AZF37_RS06165	ENOG4105C8T	Leucyl-tRNA synthetase
AZF37_RS06235	ENOG4108Q52	Methyltransferase cognate corrinoid protein
AZF37_RS06275	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AZF37_RS06280	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AZF37_RS06285	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AZF37_RS06295	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AZF37_RS06305	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AZF37_RS06310	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AZF37_RS06315	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AZF37_RS06325	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AZF37_RS06330	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AZF37_RS06350	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AZF37_RS06355	ENOG4105CNW	domain protein
AZF37_RS06365	ENOG4105C7W	Xanthine dehydrogenase
AZF37_RS06375	ENOG4105C7W	Xanthine dehydrogenase
AZF37_RS06400	ENOG4105E0C	molybdate abc transporter
AZF37_RS06405	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AZF37_RS06420	ENOG4105CIN	aminoacyl-histidine dipeptidase
AZF37_RS06485	ENOG4105X71	Membrane
AZF37_RS06560	ENOG4105C7W	Xanthine dehydrogenase
AZF37_RS06635	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AZF37_RS06660	ENOG4105C7W	Xanthine dehydrogenase
AZF37_RS06685	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AZF37_RS06690	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AZF37_RS06715	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AZF37_RS06750	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AZF37_RS06775	ENOG4105VZ8	Transcriptional regulator
AZF37_RS06785	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AZF37_RS06795	ENOG4105MAX	Superoxide reductase
AZF37_RS06815	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AZF37_RS06820	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
AZF37_RS06870	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AZF37_RS06875	ENOG4105C0B	DNA polymerase III (alpha subunit)
AZF37_RS06895	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AZF37_RS06920	ENOG4108RAC	Rubrerythrin
AZF37_RS06935	ENOG4107RWR	Sodium hydrogen exchanger
AZF37_RS06940	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
AZF37_RS06950	ENOG4105K63	Thioredoxin
AZF37_RS06990	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZF37_RS06995	ENOG4105EEI	dihydropteroate synthase
AZF37_RS07005	ENOG4105CRQ	synthase (Component I)
AZF37_RS07040	ENOG4105BZ1	(ABC) transporter
AZF37_RS07045	ENOG410801F	ribosomal-protein-alanine acetyltransferase
AZF37_RS07050	ENOG41072GX	Peptidase M22 Glycoprotease
AZF37_RS07055	ENOG4105K8N	protein family UPF0079, ATPase
AZF37_RS07060	ENOG4105CI2	imidazolone-5-propionate hydrolase
AZF37_RS07065	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AZF37_RS07070	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AZF37_RS07075	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AZF37_RS07135	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
AZF37_RS07185	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AZF37_RS07195	ENOG4105ETE	Transcriptional regulator (LacI family
AZF37_RS07250	ENOG4107RBB	ABC transporter, permease
AZF37_RS07300	ENOG4108D32	Methyltransferase
AZF37_RS07325	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AZF37_RS07355	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AZF37_RS07465	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
AZF37_RS07470	ENOG4105EPR	degv family
AZF37_RS07490	ENOG4105C2W	permease
AZF37_RS07495	ENOG4105C2W	permease
AZF37_RS07500	ENOG4105C2W	permease
AZF37_RS07565	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AZF37_RS07575	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AZF37_RS07625	ENOG4105BZ4	penicillin-binding protein
AZF37_RS07630	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AZF37_RS07635	ENOG4105BZ4	penicillin-binding protein
AZF37_RS07650	ENOG4105DQ6	Transposase
AZF37_RS07655	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AZF37_RS07660	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AZF37_RS07665	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AZF37_RS07670	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AZF37_RS07690	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AZF37_RS07695	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AZF37_RS07705	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AZF37_RS07710	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AZF37_RS07715	ENOG4105C2M	dna polymerase I
AZF37_RS07745	ENOG4105UIB	(ABC) transporter
AZF37_RS07750	ENOG4108JQ9	ABC transporter
AZF37_RS07755	ENOG4105C2J	ABC transporter
AZF37_RS07760	ENOG4108JQ9	ABC transporter
AZF37_RS07765	ENOG4105CPN	adenine deaminase
AZF37_RS07770	ENOG4105CPN	adenine deaminase
AZF37_RS07780	ENOG4105CPN	adenine deaminase
AZF37_RS07805	ENOG4108VXD	carboxy-peptidase
AZF37_RS07825	ENOG4105CAQ	asparagine synthetase
AZF37_RS07840	ENOG4105C3M	thioredoxin reductase
AZF37_RS07845	ENOG4105C0H	protease
AZF37_RS07855	ENOG4107Y9E	nuclease
AZF37_RS07865	ENOG4105C22	threonyL-tRNA synthetase
AZF37_RS07895	ENOG4108IJ6	ABC transporter
AZF37_RS07900	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
AZF37_RS07920	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AZF37_RS07935	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AZF37_RS07940	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
AZF37_RS07950	ENOG4105C8N	cysteinyl-tRNA synthetase
AZF37_RS07955	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AZF37_RS07965	ENOG4105CTP	PilT protein domain protein
AZF37_RS07970	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AZF37_RS07975	ENOG4107XAV	metallophosphoesterase
AZF37_RS08015	ENOG4107RCH	Diaminopropionate ammonia-lyase
AZF37_RS08020	ENOG4108Z6B	deaminase
AZF37_RS08060	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AZF37_RS08070	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AZF37_RS08075	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AZF37_RS08085	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AZF37_RS08090	ENOG4107T7U	Sulfatase
AZF37_RS08150	ENOG4105CIZ	coA-substrate-specific enzyme activase
AZF37_RS08155	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
AZF37_RS08160	ENOG4108IG5	Transcriptional regulator
AZF37_RS08275	ENOG4105CPN	adenine deaminase
AZF37_RS08280	ENOG4105C7N	Xanthine uracil vitamin C permease
AZF37_RS08340	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AZF37_RS08345	ENOG4105F8V	Hydrolase, tatD family
AZF37_RS08350	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AZF37_RS08360	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AZF37_RS08365	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AZF37_RS08375	ENOG4105MA4	psp1 domain protein
AZF37_RS08385	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AZF37_RS08405	ENOG4105CXN	decarboxylase
AZF37_RS08410	ENOG4105C28	cystathionine
AZF37_RS08445	ENOG4105CHM	Aminotransferase
AZF37_RS08460	ENOG4105KWG	Pfam:DUF1696
AZF37_RS08490	ENOG4107SSZ	Phosphatase
AZF37_RS08500	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AZF37_RS08505	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AZF37_RS08535	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AZF37_RS08540	ENOG4105C59	p-type ATPase
AZF37_RS08550	ENOG4107TE5	Lipid kinase
AZF37_RS08565	ENOG4108UUM	single-stranded DNA-binding protein
AZF37_RS08570	ENOG4105VDK	protein, conserved in bacteria
AZF37_RS08615	ENOG4105MZU	cell filamentation protein
AZF37_RS08625	ENOG4107TH8	cina domain protein
AZF37_RS08635	ENOG4105D2N	Aldolase
AZF37_RS08665	ENOG4108UJD	30S ribosomal protein S9
AZF37_RS08670	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AZF37_RS08675	ENOG4105VXR	cytoplasmic protein
AZF37_RS08695	ENOG4105C8Y	Acetylornithine aminotransferase
AZF37_RS08700	ENOG4105CAS	nag kinase
AZF37_RS08705	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AZF37_RS08710	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AZF37_RS08760	ENOG4105CPN	adenine deaminase
AZF37_RS08785	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AZF37_RS08790	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AZF37_RS08800	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AZF37_RS08805	ENOG4105CDU	Replicative dna helicase
AZF37_RS08810	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AZF37_RS08855	ENOG4105C83	adenylosuccinate lyase
AZF37_RS08860	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AZF37_RS08865	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AZF37_RS08870	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AZF37_RS08915	ENOG4105KWG	Pfam:DUF1696
AZF37_RS08925	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AZF37_RS08965	ENOG4105YA8	Transcriptional regulator
AZF37_RS09070	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AZF37_RS09075	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AZF37_RS09080	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AZF37_RS09105	ENOG4105CE1	Ferrous iron transport protein b
AZF37_RS09110	ENOG4107QW4	alcohol dehydrogenase
AZF37_RS09115	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
AZF37_RS09165	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AZF37_RS09175	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AZF37_RS09180	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AZF37_RS09295	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AZF37_RS09300	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AZF37_RS09315	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AZF37_RS09320	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AZF37_RS09325	ENOG4105CHR	reductase
AZF37_RS09330	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AZF37_RS09335	ENOG4105EA8	2-Nitropropane dioxygenase
AZF37_RS09340	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AZF37_RS09345	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AZF37_RS09350	ENOG4108FRU	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AZF37_RS09355	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AZF37_RS09360	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AZF37_RS09370	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AZF37_RS09375	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AZF37_RS09395	ENOG4105CKU	formyltetrahydrofolate synthetase
AZF37_RS09400	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AZF37_RS09410	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AZF37_RS09450	ENOG41060GV	RNA binding s1 domain protein
AZF37_RS09465	ENOG41082I2	s4 domain protein
AZF37_RS09475	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AZF37_RS09490	ENOG4108JA2	transcriptioN-repair coupling factor
AZF37_RS09505	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AZF37_RS09510	ENOG4105C6E	dna polymerase iii
AZF37_RS09570	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AZF37_RS09595	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AZF37_RS09600	ENOG4105CAK	Cell division ATP-binding protein ftsE
AZF37_RS09605	ENOG4108IUS	Transketolase
AZF37_RS09610	ENOG4108HHA	Transketolase
AZF37_RS09655	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AZF37_RS09660	ENOG4105CSM	endonuclease III
AZF37_RS09665	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AZF37_RS09675	ENOG4105DBI	uridine monophosphokinase
AZF37_RS09685	ENOG4105C34	Pseudouridine synthase
AZF37_RS09690	ENOG4105DR9	pseudouridine synthase
AZF37_RS09695	ENOG4105FDU	atp-dependent rna helicase
AZF37_RS09700	ENOG4107XGZ	Hydrolase
AZF37_RS09705	ENOG4105WPN	DNA integration recombination invertion protein
AZF37_RS09730	ENOG4107QNR	UPF0135 protein
AZF37_RS09745	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
AZF37_RS09750	ENOG4108JJB	ABC transporter
AZF37_RS09755	ENOG4108JJB	ABC transporter
AZF37_RS09850	ENOG4107QJE	Chromosome Partitioning Protein
AZF37_RS09855	ENOG4105FA0	parb-like partition protein
AZF37_RS09860	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AZF37_RS09865	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
AZF37_RS09870	ENOG4105EM7	Selenocysteine-specific translation elongation factor
AZF37_RS09875	ENOG4108VPT	UPF0234 protein
AZF37_RS09900	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AZF37_RS09945	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AZF37_RS10040	ENOG4105CAR	Terminase, large subunit
AZF37_RS10085	ENOG4105C8J	)-transporter