locus-tag	class	description
BSEPE_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSEPE_RS00010	COG0592	DNA-directed DNA polymerase activity
BSEPE_RS00035	COG1793	dna ligase
BSEPE_RS00045	COG0495	leucyl-tRNA aminoacylation
BSEPE_RS00050	COG0167	dihydroorotate dehydrogenase activity
BSEPE_RS00055	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BSEPE_RS00065	COG0625	glutathione transferase activity
BSEPE_RS00070	COG2857	Cytochrome c1
BSEPE_RS00075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSEPE_RS00080	COG0723	plastoquinol--plastocyanin reductase activity
BSEPE_RS00090	COG0653	protein targeting
BSEPE_RS00095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BSEPE_RS00105	COG0418	dihydroorotase activity
BSEPE_RS00115	COG0196	riboflavin kinase activity
BSEPE_RS00120	COG1194	a g-specific adenine glycosylase
BSEPE_RS00125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BSEPE_RS00135	COG0436	Aminotransferase
BSEPE_RS00150	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSEPE_RS00160	COG0739	heme binding
BSEPE_RS00160	COG0741	lytic transglycosylase activity
BSEPE_RS00160	COG1196	nuclear chromosome segregation
BSEPE_RS00165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSEPE_RS00170	COG0575	Belongs to the CDS family
BSEPE_RS00195	COG0107	imidazoleglycerol-phosphate synthase activity
BSEPE_RS00205	COG0109	protoheme IX farnesyltransferase activity
BSEPE_RS00215	COG1612	heme a metabolic process
BSEPE_RS00225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSEPE_RS00230	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BSEPE_RS00235	COG1845	cytochrome c oxidase, subunit III
BSEPE_RS00270	COG1674	ftsk spoiiie
BSEPE_RS00275	COG0492	ferredoxin-NADP+ reductase activity
BSEPE_RS00285	COG3079	Belongs to the UPF0149 family
BSEPE_RS00290	COG0540	Belongs to the ATCase OTCase family
BSEPE_RS00295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSEPE_RS00300	COG2951	lytic endotransglycosylase activity
BSEPE_RS00305	COG1477	protein flavinylation
BSEPE_RS00310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSEPE_RS00315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSEPE_RS00330	COG3328	transposase activity
BSEPE_RS00335	COG0189	ligase activity
BSEPE_RS00365	COG0779	Required for maturation of 30S ribosomal subunits
BSEPE_RS00370	COG0195	Participates in both transcription termination and antitermination
BSEPE_RS00375	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSEPE_RS00380	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSEPE_RS00385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSEPE_RS00400	COG0151	Belongs to the GarS family
BSEPE_RS00410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSEPE_RS00430	COG2181	nitrate reductase activity
BSEPE_RS00435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BSEPE_RS00445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BSEPE_RS00465	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSEPE_RS00470	COG2823	Periplasmic or secreted lipoprotein
BSEPE_RS00475	COG0792	nuclease activity
BSEPE_RS00480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSEPE_RS00490	COG0237	dephospho-CoA kinase activity
BSEPE_RS00505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BSEPE_RS00510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSEPE_RS00520	COG0126	phosphoglycerate kinase activity
BSEPE_RS00535	COG0445	tRNA wobble uridine modification
BSEPE_RS00540	COG0357	Ribosomal RNA small subunit methyltransferase G
BSEPE_RS00565	COG0084	hydrolase, TatD family'
BSEPE_RS00575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSEPE_RS00580	COG2171	N-acyltransferase activity
BSEPE_RS00585	COG1121	(ABC) transporter
BSEPE_RS00590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSEPE_RS00590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSEPE_RS00620	COG0018	arginyl-trna synthetase
BSEPE_RS00625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSEPE_RS00635	COG1074	ATP-dependent DNA helicase activity
BSEPE_RS00640	COG0352	thiamine-phosphate diphosphorylase activity
BSEPE_RS00655	COG2046	Belongs to the sulfate adenylyltransferase family
BSEPE_RS00680	COG1047	Peptidyl-prolyl cis-trans
BSEPE_RS00695	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BSEPE_RS00700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSEPE_RS00705	COG1862	Preprotein translocase
BSEPE_RS00710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSEPE_RS00715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSEPE_RS00725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSEPE_RS00755	COG0285	dihydrofolate synthase activity
BSEPE_RS00770	COG0708	Exodeoxyribonuclease III
BSEPE_RS00775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSEPE_RS00780	COG0513	Belongs to the DEAD box helicase family
BSEPE_RS00790	COG0138	bifunctional purine biosynthesis protein purh
BSEPE_RS00820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSEPE_RS00825	COG1793	dna ligase
BSEPE_RS00870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSEPE_RS00875	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSEPE_RS00880	COG1131	(ABC) transporter
BSEPE_RS00885	COG0842	Transport permease protein
BSEPE_RS00890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSEPE_RS00895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BSEPE_RS00910	COG0351	phosphomethylpyrimidine kinase
BSEPE_RS00915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSEPE_RS00920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BSEPE_RS00955	COG0131	Imidazoleglycerol-phosphate dehydratase
BSEPE_RS00960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSEPE_RS00970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSEPE_RS00975	COG2925	Exonuclease
BSEPE_RS00980	COG1278	Cold shock
BSEPE_RS00990	COG0513	Belongs to the DEAD box helicase family
BSEPE_RS01005	COG3278	Belongs to the heme-copper respiratory oxidase family
BSEPE_RS01015	COG2010	Cytochrome c
BSEPE_RS01035	COG3223	Belongs to the PsiE family
BSEPE_RS01045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BSEPE_RS01050	COG0084	hydrolase, TatD family'
BSEPE_RS01055	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSEPE_RS01060	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSEPE_RS01070	COG0406	alpha-ribazole phosphatase activity
BSEPE_RS01075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSEPE_RS01080	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSEPE_RS01090	COG0512	Glutamine amidotransferase of anthranilate synthase
BSEPE_RS01095	COG2226	methyltransferase
BSEPE_RS01100	COG3161	chorismate lyase activity
BSEPE_RS01135	COG2204	response regulator
BSEPE_RS01150	COG0375	protein maturation
BSEPE_RS01155	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BSEPE_RS01160	COG1773	rubredoxin
BSEPE_RS01170	COG1773	rubredoxin
BSEPE_RS01205	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BSEPE_RS01220	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BSEPE_RS01225	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BSEPE_RS01235	COG0288	reversible hydration of carbon dioxide
BSEPE_RS01250	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BSEPE_RS01260	COG3328	transposase activity
BSEPE_RS01280	COG0045	succinate-CoA ligase (ADP-forming) activity
BSEPE_RS01295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSEPE_RS01300	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BSEPE_RS01310	COG2983	Belongs to the UPF0260 family
BSEPE_RS01320	COG0137	argininosuccinate synthase activity
BSEPE_RS01335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSEPE_RS01345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BSEPE_RS01350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSEPE_RS01355	COG0737	Belongs to the 5'-nucleotidase family
BSEPE_RS01380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSEPE_RS01385	COG0049	tRNA binding
BSEPE_RS01390	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSEPE_RS01395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSEPE_RS01400	COG0051	transcription antitermination factor activity, RNA binding
BSEPE_RS01405	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSEPE_RS01410	COG0088	Forms part of the polypeptide exit tunnel
BSEPE_RS01415	COG0089	rRNA binding
BSEPE_RS01420	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSEPE_RS01425	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSEPE_RS01430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSEPE_RS01435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSEPE_RS01440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSEPE_RS01445	COG0255	Belongs to the universal ribosomal protein uL29 family
BSEPE_RS01450	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSEPE_RS01455	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSEPE_RS01460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BSEPE_RS01465	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSEPE_RS01470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSEPE_RS01475	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSEPE_RS01480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSEPE_RS01485	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSEPE_RS01490	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSEPE_RS01500	COG0200	Binds to the 23S rRNA
BSEPE_RS01505	COG0201	protein transport
BSEPE_RS01510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSEPE_RS01515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSEPE_RS01520	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSEPE_RS01525	COG0202	RNA polymerase activity
BSEPE_RS01530	COG0203	ribosomal protein L17
BSEPE_RS01535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSEPE_RS01545	COG1610	YqeY-like protein
BSEPE_RS01550	COG3328	transposase activity
BSEPE_RS01580	COG1450	Type ii and iii secretion system protein
BSEPE_RS01590	COG0730	response to heat
BSEPE_RS01595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSEPE_RS01615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BSEPE_RS01635	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSEPE_RS01640	COG0740	serine-type endopeptidase activity
BSEPE_RS01645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSEPE_RS01650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSEPE_RS01655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSEPE_RS01665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSEPE_RS01670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSEPE_RS01675	COG3123	guanosine phosphorylase activity
BSEPE_RS01680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSEPE_RS01720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSEPE_RS01730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSEPE_RS01745	COG2210	Belongs to the sulfur carrier protein TusA family
BSEPE_RS01750	COG0425	Belongs to the sulfur carrier protein TusA family
BSEPE_RS01755	COG4783	chaperone-mediated protein folding
BSEPE_RS01760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BSEPE_RS01765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSEPE_RS01770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSEPE_RS01780	COG2132	Multicopper oxidase
BSEPE_RS01795	COG2132	Multicopper oxidase
BSEPE_RS01800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSEPE_RS01805	COG0543	2 iron, 2 sulfur cluster binding
BSEPE_RS01810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSEPE_RS01825	COG0312	modulator of DNA gyrase
BSEPE_RS01830	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSEPE_RS01835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSEPE_RS01840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSEPE_RS01845	COG0649	NAD binding
BSEPE_RS01850	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BSEPE_RS01855	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSEPE_RS01870	COG1034	ATP synthesis coupled electron transport
BSEPE_RS01875	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSEPE_RS01880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSEPE_RS01890	COG0713	ATP synthesis coupled electron transport
BSEPE_RS01905	COG1007	ATP synthesis coupled electron transport
BSEPE_RS01910	COG2226	methyltransferase
BSEPE_RS01920	COG0500	methyltransferase
BSEPE_RS01930	COG0233	cytoplasmic translational termination
BSEPE_RS01935	COG0528	UMP kinase activity
BSEPE_RS01940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSEPE_RS01950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSEPE_RS01955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSEPE_RS01960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSEPE_RS01975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSEPE_RS01975	COG1648	precorrin-2 dehydrogenase activity
BSEPE_RS01990	COG0560	Phosphoserine phosphatase
BSEPE_RS02010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSEPE_RS02015	COG0336	Belongs to the RNA methyltransferase TrmD family
BSEPE_RS02020	COG0347	Belongs to the P(II) protein family
BSEPE_RS02025	COG0004	ammonium transporteR
BSEPE_RS02030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSEPE_RS02040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSEPE_RS02045	COG0347	Belongs to the P(II) protein family
BSEPE_RS02050	COG0004	ammonium transporteR
BSEPE_RS02055	COG3707	response regulator
BSEPE_RS02065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSEPE_RS02070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSEPE_RS02075	COG0140	phosphoribosyl-ATP diphosphatase activity
BSEPE_RS02080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSEPE_RS02100	COG0678	peroxiredoxin activity
BSEPE_RS02100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSEPE_RS02105	COG0583	DNA-binding transcription factor activity
BSEPE_RS02110	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSEPE_RS02115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BSEPE_RS02120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSEPE_RS02125	COG1560	Kdo2-lipid A biosynthetic process
BSEPE_RS02130	COG0358	DNA primase activity
BSEPE_RS02155	COG0275	rRNA processing
BSEPE_RS02160	COG2001	Belongs to the MraZ family
BSEPE_RS02170	COG0281	malic enzyme
BSEPE_RS02190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSEPE_RS02210	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSEPE_RS02215	COG0081	regulation of translation
BSEPE_RS02220	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSEPE_RS02225	COG0222	ribosome binding
BSEPE_RS02230	COG0085	RNA polymerase activity
BSEPE_RS02235	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSEPE_RS02260	COG3258	Cytochrome c
BSEPE_RS02270	COG0587	DNA-directed DNA polymerase activity
BSEPE_RS02280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSEPE_RS02285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSEPE_RS02285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSEPE_RS02290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSEPE_RS02295	COG2137	regulation of response to DNA damage stimulus
BSEPE_RS02300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSEPE_RS02340	COG0500	methyltransferase
BSEPE_RS02360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSEPE_RS02370	COG0076	glutamate decarboxylase activity
BSEPE_RS02385	COG2918	glutathione biosynthetic process
BSEPE_RS02385	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSEPE_RS02385	COG0189	ligase activity
BSEPE_RS02405	COG1595	DNA-templated transcription, initiation
BSEPE_RS02420	COG3220	belongs to the UPF0276 family
BSEPE_RS02435	COG0069	glutamate synthase activity
BSEPE_RS02445	COG1012	belongs to the aldehyde dehydrogenase family
BSEPE_RS02475	COG1132	(ABC) transporter
BSEPE_RS02480	COG0504	CTP synthase activity
BSEPE_RS02490	COG1160	GTP binding
BSEPE_RS02495	COG2976	Protein conserved in bacteria
BSEPE_RS02500	COG0124	histidyl-tRNA synthetase
BSEPE_RS02515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BSEPE_RS02520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSEPE_RS02525	COG0305	Participates in initiation and elongation during chromosome replication
BSEPE_RS02530	COG0359	binds to the 23S rRNA
BSEPE_RS02535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSEPE_RS02540	COG0360	Binds together with S18 to 16S ribosomal RNA
BSEPE_RS02545	COG2003	Belongs to the UPF0758 family
BSEPE_RS02550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSEPE_RS02555	COG1214	PFAM Peptidase M22, glycoprotease
BSEPE_RS02570	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BSEPE_RS02575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSEPE_RS02580	COG0776	regulation of translation
BSEPE_RS02595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSEPE_RS02610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSEPE_RS02635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSEPE_RS02640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSEPE_RS02645	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSEPE_RS02650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSEPE_RS02660	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSEPE_RS02665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSEPE_RS02665	COG0072	phenylalanine-tRNA ligase activity
BSEPE_RS02670	COG0776	regulation of translation
BSEPE_RS02680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSEPE_RS02695	COG0525	valine-tRNA ligase activity
BSEPE_RS02700	COG2827	Endonuclease containing a URI domain
BSEPE_RS02715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSEPE_RS02720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSEPE_RS02735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSEPE_RS02750	COG1686	Belongs to the peptidase S11 family
BSEPE_RS02755	COG2951	lytic endotransglycosylase activity
BSEPE_RS02760	COG0772	Belongs to the SEDS family
BSEPE_RS02765	COG3737	Protein of unknown function (DUF498/DUF598)
BSEPE_RS02805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSEPE_RS02810	COG0259	pyridoxamine-phosphate oxidase activity
BSEPE_RS02815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSEPE_RS02820	COG1530	ribonuclease E activity
BSEPE_RS02825	COG1028	Short-chain dehydrogenase reductase Sdr
BSEPE_RS02835	COG0308	aminopeptidase N
BSEPE_RS02840	COG1546	Belongs to the CinA family
BSEPE_RS02840	COG1058	Belongs to the CinA family
BSEPE_RS02865	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BSEPE_RS02870	COG0028	Belongs to the TPP enzyme family
BSEPE_RS02880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSEPE_RS02885	COG1183	phosphatidylcholine synthase activity
BSEPE_RS02890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSEPE_RS02900	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSEPE_RS02905	COG5265	(ABC) transporter
BSEPE_RS02910	COG0343	queuine tRNA-ribosyltransferase activity
BSEPE_RS02920	COG0768	penicillin binding
BSEPE_RS02935	COG1077	Cell shape determining protein MreB Mrl
BSEPE_RS02940	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BSEPE_RS02940	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BSEPE_RS02950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSEPE_RS02955	COG1376	ErfK ybiS ycfS ynhG family protein
BSEPE_RS02970	COG1472	Belongs to the glycosyl hydrolase 3 family
BSEPE_RS02985	COG0210	DNA helicase
BSEPE_RS02995	COG1509	lysine 2,3-aminomutase activity
BSEPE_RS03000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSEPE_RS03005	COG1393	Belongs to the ArsC family
BSEPE_RS03015	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSEPE_RS03025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSEPE_RS03045	COG4974	Belongs to the 'phage' integrase family
BSEPE_RS03060	COG1396	sequence-specific DNA binding
BSEPE_RS03090	COG0270	DNA (cytosine-5-)-methyltransferase activity
BSEPE_RS03120	COG0740	serine-type endopeptidase activity
BSEPE_RS03225	COG4695	Portal protein
BSEPE_RS03270	COG0564	pseudouridine synthase activity
BSEPE_RS03290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSEPE_RS03300	COG0354	folic acid binding
BSEPE_RS03305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BSEPE_RS03310	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSEPE_RS03315	COG0180	Tryptophanyl-tRNA synthetase
BSEPE_RS03320	COG1187	pseudouridine synthase activity
BSEPE_RS03325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSEPE_RS03330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSEPE_RS03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSEPE_RS03345	COG0154	amidase activity
BSEPE_RS03350	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BSEPE_RS03355	COG3645	SOS response
BSEPE_RS03370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSEPE_RS03375	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BSEPE_RS03380	COG1994	Peptidase M50
BSEPE_RS03385	COG0442	prolyl-tRNA aminoacylation
BSEPE_RS03390	COG0688	phosphatidylethanolamine metabolic process
BSEPE_RS03395	COG4536	flavin adenine dinucleotide binding
BSEPE_RS03400	COG0148	phosphopyruvate hydratase activity
BSEPE_RS03405	COG0484	heat shock protein binding
BSEPE_RS03410	COG0443	Heat shock 70 kDa protein
BSEPE_RS03420	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BSEPE_RS03430	COG0776	regulation of translation
BSEPE_RS03515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSEPE_RS03545	COG3306	glycosyltransferase involved in LPS biosynthesis
BSEPE_RS03560	COG0438	transferase activity, transferring glycosyl groups
BSEPE_RS03565	COG1216	Glycosyl transferase, family 2
BSEPE_RS03575	COG1215	transferase activity, transferring glycosyl groups
BSEPE_RS03580	COG1215	transferase activity, transferring glycosyl groups
BSEPE_RS03585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSEPE_RS03590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSEPE_RS03595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSEPE_RS03600	COG1596	polysaccharide export
BSEPE_RS03605	COG3206	protein involved in exopolysaccharide biosynthesis
BSEPE_RS03605	COG0489	protein tyrosine kinase activity
BSEPE_RS03615	COG0436	Aminotransferase
BSEPE_RS03620	COG0556	nucleotide-excision repair
BSEPE_RS03625	COG0602	queuosine metabolic process
BSEPE_RS03630	COG0071	Belongs to the small heat shock protein (HSP20) family
BSEPE_RS03635	COG0659	secondary active sulfate transmembrane transporter activity
BSEPE_RS03640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSEPE_RS03660	COG0284	orotidine-5'-phosphate decarboxylase activity
BSEPE_RS03685	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BSEPE_RS03705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSEPE_RS03710	COG0617	tRNA 3'-terminal CCA addition
BSEPE_RS03715	COG0300	oxidoreductase activity
BSEPE_RS03720	COG1722	exodeoxyribonuclease VII activity
BSEPE_RS03725	COG0142	geranyltranstransferase activity
BSEPE_RS03730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSEPE_RS03735	COG0416	fatty acid biosynthetic process
BSEPE_RS03740	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSEPE_RS03750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSEPE_RS03765	COG0330	HflC and HflK could
BSEPE_RS03770	COG0330	HflC and HflK could
BSEPE_RS03775	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BSEPE_RS03780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSEPE_RS03785	COG0557	exoribonuclease II activity
BSEPE_RS03800	COG1519	Transferase
BSEPE_RS03805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSEPE_RS03810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSEPE_RS03815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSEPE_RS03820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSEPE_RS03825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSEPE_RS03830	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSEPE_RS03830	COG0316	Belongs to the HesB IscA family
BSEPE_RS03835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BSEPE_RS03840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSEPE_RS03845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSEPE_RS03865	COG0538	isocitrate dehydrogenase activity
BSEPE_RS03905	COG4206	TonB-dependent receptor
BSEPE_RS03910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BSEPE_RS03915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSEPE_RS03920	COG1605	Chorismate mutase
BSEPE_RS03920	COG0077	Prephenate dehydratase
BSEPE_RS03925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSEPE_RS03930	COG0287	Prephenate dehydrogenase
BSEPE_RS03935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSEPE_RS03940	COG2920	part of a sulfur-relay system
BSEPE_RS03950	COG1475	DNA binding
BSEPE_RS03955	COG1192	Involved in chromosome partitioning
BSEPE_RS03960	COG0793	Belongs to the peptidase S41A family
BSEPE_RS04000	COG3177	Filamentation induced by cAMP protein fic
BSEPE_RS04030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BSEPE_RS04035	COG2824	Alkylphosphonate utilization operon protein PhnA
BSEPE_RS04050	COG0571	ribonuclease III activity
BSEPE_RS04055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSEPE_RS04060	COG1381	Involved in DNA repair and RecF pathway recombination
BSEPE_RS04065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BSEPE_RS04070	COG0736	holo-[acyl-carrier-protein] synthase activity
BSEPE_RS04085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSEPE_RS04090	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSEPE_RS04095	COG0481	GTPase activity
BSEPE_RS04100	COG4137	Cytochrome C assembly protein
BSEPE_RS04105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSEPE_RS04115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSEPE_RS04120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSEPE_RS04130	COG0322	excinuclease ABC activity
BSEPE_RS04135	COG0546	phosphoglycolate phosphatase activity
BSEPE_RS04135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSEPE_RS04150	COG0432	Pfam Uncharacterised protein family UPF0047
BSEPE_RS04165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSEPE_RS04180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSEPE_RS04185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSEPE_RS04205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSEPE_RS04230	COG2850	peptidyl-arginine hydroxylation
BSEPE_RS04235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSEPE_RS04240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSEPE_RS04260	COG2194	sulfuric ester hydrolase activity
BSEPE_RS04265	COG0795	lipopolysaccharide-transporting ATPase activity
BSEPE_RS04290	COG1047	Peptidyl-prolyl cis-trans
BSEPE_RS04305	COG1162	GTPase activity
BSEPE_RS04315	COG0501	Belongs to the peptidase M48B family
BSEPE_RS04335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSEPE_RS04350	COG3422	double-strand break repair
BSEPE_RS04395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BSEPE_RS04395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSEPE_RS04400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSEPE_RS04405	COG4597	amino acid ABC transporter
BSEPE_RS04410	COG0765	amino acid transport
BSEPE_RS04415	COG1126	abc transporter atp-binding protein
BSEPE_RS04430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BSEPE_RS04435	COG0543	2 iron, 2 sulfur cluster binding
BSEPE_RS04435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSEPE_RS04445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSEPE_RS04450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSEPE_RS04460	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BSEPE_RS04465	COG0709	Synthesizes selenophosphate from selenide and ATP
BSEPE_RS04475	COG2304	oxidoreductase activity
BSEPE_RS04495	COG0714	Associated with various cellular activities
BSEPE_RS04505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSEPE_RS04510	COG3864	Putative metallopeptidase domain
BSEPE_RS04530	COG2921	Belongs to the UPF0250 family
BSEPE_RS04535	COG0321	lipoyl(octanoyl) transferase activity
BSEPE_RS04540	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSEPE_RS04545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSEPE_RS04555	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSEPE_RS04560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSEPE_RS04565	COG2967	ApaG domain
BSEPE_RS04575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSEPE_RS04590	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSEPE_RS04595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSEPE_RS04600	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSEPE_RS04605	COG0728	peptidoglycan biosynthetic process
BSEPE_RS04610	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BSEPE_RS04615	COG0194	GDP metabolic process
BSEPE_RS04625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSEPE_RS04630	COG0459	protein refolding
BSEPE_RS04640	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BSEPE_RS04645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSEPE_RS04650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSEPE_RS04660	COG0339	signal peptide processing
BSEPE_RS04670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSEPE_RS04675	COG0489	protein tyrosine kinase activity
BSEPE_RS04690	COG0443	Heat shock 70 kDa protein
BSEPE_RS04700	COG0316	Belongs to the HesB IscA family
BSEPE_RS04705	COG0822	iron-sulfur transferase activity
BSEPE_RS04710	COG1104	cysteine desulfurase activity
BSEPE_RS04725	COG1560	Kdo2-lipid A biosynthetic process
BSEPE_RS04730	COG0037	tRNA processing
BSEPE_RS04760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSEPE_RS04765	COG2885	chlorophyll binding
BSEPE_RS04770	COG0823	Involved in the tonB-independent uptake of proteins
BSEPE_RS04780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSEPE_RS04790	COG2814	Major facilitator Superfamily
BSEPE_RS04795	COG0629	single-stranded DNA binding
BSEPE_RS04800	COG0537	adenosine 5'-monophosphoramidase activity
BSEPE_RS04810	COG1410	methionine synthase
BSEPE_RS04810	COG0646	methionine synthase
BSEPE_RS04815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSEPE_RS04820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSEPE_RS04850	COG0488	(ABC) transporter
BSEPE_RS04855	COG0772	Belongs to the SEDS family
BSEPE_RS04860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSEPE_RS04865	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BSEPE_RS04870	COG0174	glutamine synthetase
BSEPE_RS04875	COG0425	Belongs to the sulfur carrier protein TusA family
BSEPE_RS04875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSEPE_RS04880	COG0408	coproporphyrinogen oxidase activity
BSEPE_RS04890	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BSEPE_RS04895	COG0326	Molecular chaperone. Has ATPase activity
BSEPE_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
BSEPE_RS04925	COG1322	Protein conserved in bacteria
BSEPE_RS04940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSEPE_RS04945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSEPE_RS04945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BSEPE_RS04950	COG0129	dihydroxy-acid dehydratase activity
BSEPE_RS04960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BSEPE_RS04980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSEPE_RS04985	COG1758	RNA polymerase activity
BSEPE_RS04990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSEPE_RS05015	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BSEPE_RS05025	COG1704	LemA family
BSEPE_RS05030	COG0501	Belongs to the peptidase M48B family
BSEPE_RS05045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSEPE_RS05050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSEPE_RS05055	COG0217	transcriptional regulatory protein
BSEPE_RS05070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BSEPE_RS05075	COG2813	Specifically methylates the guanine in position
BSEPE_RS05085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSEPE_RS05095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSEPE_RS05105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSEPE_RS05115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSEPE_RS05130	COG2833	Protein of unknown function (DUF455)
BSEPE_RS05160	COG0328	RNA-DNA hybrid ribonuclease activity
BSEPE_RS05165	COG0367	asparagine synthase
BSEPE_RS05170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSEPE_RS05175	COG0066	3-isopropylmalate dehydratase activity
BSEPE_RS05195	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BSEPE_RS05200	COG0142	geranyltranstransferase activity
BSEPE_RS05205	COG1199	ATP-dependent helicase activity
BSEPE_RS05220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSEPE_RS05260	COG3328	transposase activity
BSEPE_RS05270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSEPE_RS05275	COG0569	domain protein
BSEPE_RS05280	COG0745	RESPONSE REGULATOR receiver
BSEPE_RS05285	COG5000	phosphorelay sensor kinase activity
BSEPE_RS05290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSEPE_RS05295	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSEPE_RS05300	COG0742	ribosomal rna small subunit methyltransferase
BSEPE_RS05305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSEPE_RS05310	COG0243	molybdopterin cofactor binding
BSEPE_RS05315	COG0515	serine threonine protein kinase
BSEPE_RS05315	COG2815	serine threonine protein kinase
BSEPE_RS05320	COG2223	nitrite transmembrane transporter activity
BSEPE_RS05325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSEPE_RS05330	COG0314	molybdopterin synthase activity
BSEPE_RS05335	COG0746	molybdenum cofactor guanylyltransferase activity
BSEPE_RS05340	COG0303	'Molybdopterin
BSEPE_RS05345	COG0315	cyclic pyranopterin monophosphate synthase activity
BSEPE_RS05350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSEPE_RS05355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BSEPE_RS05360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSEPE_RS05365	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSEPE_RS05385	COG1850	ribulose-bisphosphate carboxylase activity
BSEPE_RS05395	COG0788	formyltetrahydrofolate deformylase activity
BSEPE_RS05400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSEPE_RS05420	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BSEPE_RS05425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSEPE_RS05430	COG1393	Belongs to the ArsC family
BSEPE_RS05440	COG0751	glycine-tRNA ligase activity
BSEPE_RS05445	COG0850	regulation of cytokinetic process
BSEPE_RS05465	COG0811	peptide transport
BSEPE_RS05470	COG0824	Thioesterase
BSEPE_RS05475	COG2255	four-way junction helicase activity
BSEPE_RS05485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BSEPE_RS05490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSEPE_RS05495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSEPE_RS05500	COG0735	belongs to the Fur family
BSEPE_RS05510	COG4133	protoheme IX ABC transporter activity
BSEPE_RS05515	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSEPE_RS05520	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSEPE_RS05525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSEPE_RS05540	COG0752	glycyl-tRNA synthetase alpha subunit
BSEPE_RS05545	COG1238	metal cluster binding
BSEPE_RS05555	COG0668	transmembrane transport
BSEPE_RS05560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSEPE_RS05575	COG2847	Copper chaperone PCu(A)C
BSEPE_RS05590	COG1702	phosphate starvation-inducible protein PhoH
BSEPE_RS05595	COG0482	sulfurtransferase activity
BSEPE_RS05600	COG2915	High frequency lysogenization protein hflD homolog
BSEPE_RS05605	COG0268	Binds directly to 16S ribosomal RNA
BSEPE_RS05615	COG1570	exodeoxyribonuclease VII activity
BSEPE_RS05620	COG0739	heme binding
BSEPE_RS05635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSEPE_RS05640	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSEPE_RS05645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSEPE_RS05650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSEPE_RS05655	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSEPE_RS05670	COG1388	LysM domain
BSEPE_RS05670	COG0741	lytic transglycosylase activity
BSEPE_RS05675	COG0271	Belongs to the BolA IbaG family
BSEPE_RS05680	COG0543	2 iron, 2 sulfur cluster binding
BSEPE_RS05680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSEPE_RS05685	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSEPE_RS05690	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BSEPE_RS05700	COG3328	transposase activity
BSEPE_RS05710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSEPE_RS05720	COG0494	nUDIX hydrolase
BSEPE_RS05730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BSEPE_RS05765	COG0277	FAD linked oxidase domain protein
BSEPE_RS05775	COG0612	Peptidase, M16
BSEPE_RS05780	COG0612	Peptidase, M16
BSEPE_RS05785	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BSEPE_RS05790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSEPE_RS05795	COG0552	protein localization to endoplasmic reticulum
BSEPE_RS05825	COG0181	hydroxymethylbilane synthase activity
BSEPE_RS05835	COG0165	Argininosuccinate lyase
BSEPE_RS05840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSEPE_RS05850	COG3038	cytochrome b561
BSEPE_RS05855	COG0726	polysaccharide deacetylase
BSEPE_RS05855	COG1649	PFAM Uncharacterised BCR, COG1649
BSEPE_RS05860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSEPE_RS05865	COG0542	response to heat
BSEPE_RS05870	COG4660	Part of a membrane complex involved in electron transport
BSEPE_RS05875	COG2890	protein-(glutamine-N5) methyltransferase activity
BSEPE_RS05880	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSEPE_RS05895	COG0247	lactate metabolic process
BSEPE_RS05905	COG1204	response to ionizing radiation
BSEPE_RS05920	COG0277	FAD linked oxidase domain protein
BSEPE_RS05925	COG0277	FAD linked oxidase domain protein
BSEPE_RS05940	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BSEPE_RS05945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BSEPE_RS05950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSEPE_RS05955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSEPE_RS05965	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BSEPE_RS05970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSEPE_RS05975	COG2026	Addiction module toxin, RelE StbE family
BSEPE_RS05990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BSEPE_RS05995	COG1469	GTP cyclohydrolase I activity
BSEPE_RS06005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSEPE_RS06010	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSEPE_RS06010	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSEPE_RS06015	COG0537	adenosine 5'-monophosphoramidase activity
BSEPE_RS06020	COG1252	NADH dehydrogenase
BSEPE_RS06030	COG0778	Nitroreductase
BSEPE_RS06035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BSEPE_RS06100	COG2081	HI0933 family
BSEPE_RS06105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSEPE_RS06115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSEPE_RS06120	COG2350	Protein conserved in bacteria
BSEPE_RS06125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSEPE_RS06130	COG0514	ATP-dependent DNA helicase (RecQ)
BSEPE_RS06135	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BSEPE_RS06140	COG0134	indole-3-glycerol-phosphate synthase activity
BSEPE_RS06160	COG2022	thiamine diphosphate biosynthetic process
BSEPE_RS06180	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BSEPE_RS06180	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BSEPE_RS06200	COG0156	8-amino-7-oxononanoate synthase activity
BSEPE_RS06205	COG2267	carboxylic ester hydrolase activity
BSEPE_RS06210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BSEPE_RS06230	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSEPE_RS06235	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BSEPE_RS06240	COG1663	tetraacyldisaccharide 4'-kinase activity
BSEPE_RS06245	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSEPE_RS06270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSEPE_RS06285	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BSEPE_RS06290	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BSEPE_RS06300	COG3630	sodium ion export across plasma membrane
BSEPE_RS06310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSEPE_RS06315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BSEPE_RS06340	COG0802	atpase or kinase
BSEPE_RS06350	COG1797	cobyrinic acid a,c-diamide synthase activity
BSEPE_RS06385	COG2920	part of a sulfur-relay system
BSEPE_RS06395	COG2923	Belongs to the DsrF TusC family
BSEPE_RS06400	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BSEPE_RS06405	COG2221	Nitrite and sulphite reductase 4Fe-4S
BSEPE_RS06410	COG2221	Nitrite and sulphite reductase 4Fe-4S
BSEPE_RS06415	COG0493	'glutamate synthase
BSEPE_RS06420	COG0335	large ribosomal subunit rRNA binding
BSEPE_RS06425	COG4974	Belongs to the 'phage' integrase family
BSEPE_RS06430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSEPE_RS06440	COG2853	Lipoprotein
BSEPE_RS06470	COG0301	tRNA thio-modification
BSEPE_RS06475	COG2264	protein methyltransferase activity
BSEPE_RS06485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSEPE_RS06490	COG0009	L-threonylcarbamoyladenylate synthase
BSEPE_RS06495	COG0613	PHP domain protein
BSEPE_RS06500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSEPE_RS06520	COG0166	Belongs to the GPI family
BSEPE_RS06525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSEPE_RS06530	COG2194	sulfuric ester hydrolase activity
BSEPE_RS06535	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSEPE_RS06540	COG0542	response to heat
BSEPE_RS06545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSEPE_RS06550	COG0519	Catalyzes the synthesis of GMP from XMP
BSEPE_RS06550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSEPE_RS06565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSEPE_RS06570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSEPE_RS06575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSEPE_RS06580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSEPE_RS06585	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSEPE_RS06590	COG0557	exoribonuclease II activity
BSEPE_RS06595	COG0509	glycine decarboxylation via glycine cleavage system
BSEPE_RS06600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSEPE_RS06630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSEPE_RS06635	COG4659	FMN binding
BSEPE_RS06640	COG4658	electron transport chain
BSEPE_RS06645	COG4656	Part of a membrane complex involved in electron transport
BSEPE_RS06650	COG2878	Part of a membrane complex involved in electron transport
BSEPE_RS06675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSEPE_RS06680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSEPE_RS06700	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSEPE_RS06705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSEPE_RS06715	COG0513	Belongs to the DEAD box helicase family
BSEPE_RS06730	COG0306	phosphate transporter
BSEPE_RS06735	COG1392	Phosphate transport regulator
BSEPE_RS06740	COG0825	malonyl-CoA metabolic process
BSEPE_RS06745	COG0037	tRNA processing
BSEPE_RS06750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSEPE_RS06755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BSEPE_RS06765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSEPE_RS06770	COG0546	phosphoglycolate phosphatase activity
BSEPE_RS06790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSEPE_RS06810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSEPE_RS06830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSEPE_RS06875	COG1131	(ABC) transporter
BSEPE_RS06900	COG0006	proline dipeptidase activity
BSEPE_RS06905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSEPE_RS06910	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BSEPE_RS06915	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSEPE_RS06925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSEPE_RS06930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSEPE_RS06945	COG0157	Belongs to the NadC ModD family
BSEPE_RS06950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSEPE_RS06965	COG0019	diaminopimelate decarboxylase activity
BSEPE_RS06970	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BSEPE_RS06975	COG0494	nUDIX hydrolase
BSEPE_RS07035	COG0640	Transcriptional regulator
BSEPE_RS07040	COG0477	Major facilitator Superfamily
BSEPE_RS07050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSEPE_RS07050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSEPE_RS07055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSEPE_RS07065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSEPE_RS07070	COG0473	3-isopropylmalate dehydrogenase activity
BSEPE_RS07075	COG1773	rubredoxin
BSEPE_RS07080	COG0450	alkyl hydroperoxide reductase
BSEPE_RS07085	COG0215	cysteine-tRNA ligase activity
BSEPE_RS07090	COG1011	Hydrolase
BSEPE_RS07100	COG0205	6-phosphofructokinase activity
BSEPE_RS07140	COG2197	response regulator
BSEPE_RS07145	COG3850	Histidine kinase
BSEPE_RS07150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSEPE_RS07155	COG2918	glutathione biosynthetic process
BSEPE_RS07160	COG0352	thiamine-phosphate diphosphorylase activity
BSEPE_RS07165	COG3328	transposase activity
BSEPE_RS07225	COG0606	chelatase, subunit chli
BSEPE_RS07245	COG0606	chelatase, subunit chli
BSEPE_RS07265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSEPE_RS07270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSEPE_RS07275	COG1049	propionate catabolic process, 2-methylcitrate cycle
BSEPE_RS07280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSEPE_RS07285	COG0228	four-way junction DNA binding
BSEPE_RS07290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSEPE_RS07305	COG3328	transposase activity
BSEPE_RS07315	COG0471	metal ion transport
BSEPE_RS07315	COG0490	domain, Protein
BSEPE_RS07320	COG0583	DNA-binding transcription factor activity
BSEPE_RS07325	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BSEPE_RS07335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BSEPE_RS07340	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BSEPE_RS07340	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BSEPE_RS07350	COG1137	ATPase activity
BSEPE_RS07355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSEPE_RS07360	COG0606	chelatase, subunit chli
BSEPE_RS07365	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSEPE_RS07370	COG2914	Belongs to the UPF0125 (RnfH) family
BSEPE_RS07380	COG0312	modulator of DNA gyrase
BSEPE_RS07385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSEPE_RS07390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSEPE_RS07400	COG1040	competence protein
BSEPE_RS07405	COG3022	response to hydroperoxide
BSEPE_RS07410	COG0069	glutamate synthase activity
BSEPE_RS07410	COG0070	glutamate synthase
BSEPE_RS07410	COG0067	glutamate synthase
BSEPE_RS07415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSEPE_RS07425	COG0052	Belongs to the universal ribosomal protein uS2 family
BSEPE_RS07430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BSEPE_RS07435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BSEPE_RS07440	COG0012	GTP binding
BSEPE_RS07445	COG0193	aminoacyl-tRNA hydrolase activity
BSEPE_RS07450	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSEPE_RS07455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSEPE_RS07475	COG3177	Filamentation induced by cAMP protein fic
BSEPE_RS07480	COG0316	Belongs to the HesB IscA family
BSEPE_RS07485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSEPE_RS07490	COG0439	Biotin carboxylase
BSEPE_RS07495	COG0511	ligase activity, forming carbon-carbon bonds
BSEPE_RS07500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSEPE_RS07505	COG4232	protein-disulfide reductase activity
BSEPE_RS07515	COG0563	adenylate kinase activity
BSEPE_RS07520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSEPE_RS07525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSEPE_RS07530	COG0497	DNA recombination
BSEPE_RS07535	COG1714	RDD family
BSEPE_RS07540	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSEPE_RS07550	COG0356	it plays a direct role in the translocation of protons across the membrane
BSEPE_RS07560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSEPE_RS07565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSEPE_RS07570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSEPE_RS07575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSEPE_RS07580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSEPE_RS07585	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSEPE_RS07595	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BSEPE_RS07600	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSEPE_RS07620	COG0706	membrane insertase activity
BSEPE_RS07625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSEPE_RS07630	COG0594	ribonuclease P activity
BSEPE_RS07635	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BSEPE_RS07640	COG0758	DNA mediated transformation
BSEPE_RS07645	COG2922	Belongs to the Smg family
BSEPE_RS07680	COG0135	phosphoribosylanthranilate isomerase activity
BSEPE_RS07685	COG0133	tryptophan synthase activity
BSEPE_RS07690	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSEPE_RS07695	COG0254	rRNA binding
BSEPE_RS07700	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSEPE_RS07715	COG0159	tryptophan synthase activity
BSEPE_RS07720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSEPE_RS07725	COG1047	Peptidyl-prolyl cis-trans
BSEPE_RS07730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSEPE_RS07735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSEPE_RS07745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSEPE_RS07750	COG0424	maF-like protein
BSEPE_RS07755	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BSEPE_RS07770	COG0149	triose-phosphate isomerase activity
BSEPE_RS07805	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BSEPE_RS07820	COG1841	ribosomal large subunit assembly
BSEPE_RS07825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSEPE_RS07900	COG2835	tetraacyldisaccharide 4'-kinase activity
BSEPE_RS07905	COG0606	chelatase, subunit chli
BSEPE_RS07925	COG1401	restriction endodeoxyribonuclease activity
BSEPE_RS08075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation