locus-tag	class	description
HDN1F_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDN1F_RS00010	COG0592	DNA-directed DNA polymerase activity
HDN1F_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDN1F_RS00060	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HDN1F_RS00065	COG1984	allophanate hydrolase subunit 2
HDN1F_RS00070	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HDN1F_RS00110	COG0702	epimerase
HDN1F_RS00115	COG0671	phosphoesterase, PA-phosphatase related
HDN1F_RS00125	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HDN1F_RS00135	COG0300	oxidoreductase activity
HDN1F_RS00165	COG0789	Transcriptional regulator
HDN1F_RS00170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDN1F_RS00190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDN1F_RS00205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HDN1F_RS00240	COG5002	protein histidine kinase activity
HDN1F_RS00280	COG0758	DNA mediated transformation
HDN1F_RS00325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDN1F_RS00330	COG0408	coproporphyrinogen oxidase activity
HDN1F_RS00335	COG0009	L-threonylcarbamoyladenylate synthase
HDN1F_RS00340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDN1F_RS00350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDN1F_RS00360	COG0628	permease
HDN1F_RS00365	COG0517	IMP dehydrogenase activity
HDN1F_RS00440	COG5001	Diguanylate cyclase
HDN1F_RS00440	COG5002	protein histidine kinase activity
HDN1F_RS00455	COG3437	response regulator, receiver
HDN1F_RS00455	COG2205	protein histidine kinase activity
HDN1F_RS00455	COG4999	Histidine kinase
HDN1F_RS00455	COG3850	Histidine kinase
HDN1F_RS00475	COG5002	protein histidine kinase activity
HDN1F_RS00475	COG2205	protein histidine kinase activity
HDN1F_RS00475	COG0784	Response regulator, receiver
HDN1F_RS00490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HDN1F_RS00500	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDN1F_RS00505	COG0019	diaminopimelate decarboxylase activity
HDN1F_RS00515	COG3072	Adenylate cyclase
HDN1F_RS00520	COG2202	Pas domain
HDN1F_RS00520	COG2200	EAL domain
HDN1F_RS00520	COG2199	diguanylate cyclase activity
HDN1F_RS00525	COG0165	Argininosuccinate lyase
HDN1F_RS00530	COG3275	phosphorelay sensor kinase activity
HDN1F_RS00535	COG3246	L-lysine catabolic process to acetate
HDN1F_RS00545	COG0181	hydroxymethylbilane synthase activity
HDN1F_RS00580	COG0248	Ppx GppA phosphatase
HDN1F_RS00585	COG3119	arylsulfatase activity
HDN1F_RS00620	COG0438	transferase activity, transferring glycosyl groups
HDN1F_RS00620	COG1216	Glycosyl transferase, family 2
HDN1F_RS00640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDN1F_RS00645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HDN1F_RS00650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDN1F_RS00670	COG0006	proline dipeptidase activity
HDN1F_RS00680	COG0509	glycine decarboxylation via glycine cleavage system
HDN1F_RS00685	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HDN1F_RS00690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HDN1F_RS00705	COG2183	response to ionizing radiation
HDN1F_RS00735	COG0494	nUDIX hydrolase
HDN1F_RS00750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDN1F_RS00755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDN1F_RS00770	COG3264	Mechanosensitive ion channel
HDN1F_RS00770	COG1196	nuclear chromosome segregation
HDN1F_RS00775	COG2900	Belongs to the SlyX family
HDN1F_RS00805	COG0129	dihydroxy-acid dehydratase activity
HDN1F_RS00825	COG0583	DNA-binding transcription factor activity
HDN1F_RS00840	COG0784	Response regulator, receiver
HDN1F_RS00840	COG2205	protein histidine kinase activity
HDN1F_RS00845	COG3437	response regulator, receiver
HDN1F_RS00870	COG1253	flavin adenine dinucleotide binding
HDN1F_RS00880	COG2030	dehydratase
HDN1F_RS00900	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS00905	COG0840	transmembrane signaling receptor activity
HDN1F_RS00910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HDN1F_RS00915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDN1F_RS00925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HDN1F_RS00925	COG2813	Specifically methylates the guanine in position
HDN1F_RS00930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HDN1F_RS00940	COG0745	RESPONSE REGULATOR receiver
HDN1F_RS00950	COG0643	Histidine kinase
HDN1F_RS00950	COG2198	Histidine kinase
HDN1F_RS00955	COG0835	chemotaxis
HDN1F_RS00960	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HDN1F_RS00975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HDN1F_RS00980	COG1121	(ABC) transporter
HDN1F_RS00990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HDN1F_RS01015	COG0729	surface antigen
HDN1F_RS01065	COG0657	acetylesterase activity
HDN1F_RS01070	COG0076	glutamate decarboxylase activity
HDN1F_RS01115	COG2814	Major facilitator Superfamily
HDN1F_RS01125	COG0606	chelatase, subunit chli
HDN1F_RS01130	COG0604	alcohol dehydrogenase
HDN1F_RS01155	COG0500	methyltransferase
HDN1F_RS01160	COG3268	Saccharopine dehydrogenase
HDN1F_RS01190	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS01195	COG0210	DNA helicase
HDN1F_RS01200	COG3245	cytochrome
HDN1F_RS01215	COG0215	cysteine-tRNA ligase activity
HDN1F_RS01220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDN1F_RS01260	COG0574	Belongs to the PEP-utilizing enzyme family
HDN1F_RS01260	COG3848	Pyruvate phosphate dikinase
HDN1F_RS01270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HDN1F_RS01300	COG2824	Alkylphosphonate utilization operon protein PhnA
HDN1F_RS01325	COG0183	Belongs to the thiolase family
HDN1F_RS01340	COG1902	pentaerythritol trinitrate reductase activity
HDN1F_RS01340	COG0446	pyridine nucleotide-disulphide oxidoreductase
HDN1F_RS01355	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS01360	COG1053	succinate dehydrogenase
HDN1F_RS01365	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS01395	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HDN1F_RS01420	COG4178	(ABC) transporter
HDN1F_RS01425	COG4399	Belongs to the UPF0754 family
HDN1F_RS01455	COG2081	HI0933 family
HDN1F_RS01495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDN1F_RS01500	COG1758	RNA polymerase activity
HDN1F_RS01520	COG2223	nitrite transmembrane transporter activity
HDN1F_RS01525	COG2239	Acts as a magnesium transporter
HDN1F_RS01530	COG0625	glutathione transferase activity
HDN1F_RS01535	COG0121	glutamine amidotransferase
HDN1F_RS01540	COG0784	Response regulator, receiver
HDN1F_RS01540	COG2205	protein histidine kinase activity
HDN1F_RS01560	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS01565	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS01570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDN1F_RS01575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDN1F_RS01585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HDN1F_RS01595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDN1F_RS01600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDN1F_RS01605	COG0586	Pfam SNARE associated Golgi protein
HDN1F_RS01615	COG0352	thiamine-phosphate diphosphorylase activity
HDN1F_RS01620	COG0351	phosphomethylpyrimidine kinase
HDN1F_RS01620	COG0352	thiamine-phosphate diphosphorylase activity
HDN1F_RS01660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HDN1F_RS01665	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HDN1F_RS01670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDN1F_RS01675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDN1F_RS01680	COG0268	Binds directly to 16S ribosomal RNA
HDN1F_RS01685	COG0196	riboflavin kinase activity
HDN1F_RS01690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDN1F_RS01695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDN1F_RS01700	COG1047	Peptidyl-prolyl cis-trans
HDN1F_RS01705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HDN1F_RS01780	COG0542	response to heat
HDN1F_RS01790	COG0028	Belongs to the TPP enzyme family
HDN1F_RS01800	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HDN1F_RS01805	COG1183	phosphatidylcholine synthase activity
HDN1F_RS01880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDN1F_RS01885	COG0081	regulation of translation
HDN1F_RS01890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDN1F_RS01895	COG0222	ribosome binding
HDN1F_RS01900	COG0085	RNA polymerase activity
HDN1F_RS01910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDN1F_RS01915	COG0049	tRNA binding
HDN1F_RS01920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDN1F_RS01930	COG0051	transcription antitermination factor activity, RNA binding
HDN1F_RS01935	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDN1F_RS01940	COG0088	Forms part of the polypeptide exit tunnel
HDN1F_RS01945	COG0089	rRNA binding
HDN1F_RS01950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDN1F_RS01955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDN1F_RS01960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDN1F_RS01965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDN1F_RS01970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDN1F_RS01975	COG0255	Belongs to the universal ribosomal protein uL29 family
HDN1F_RS01985	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDN1F_RS01990	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDN1F_RS01995	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDN1F_RS02000	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDN1F_RS02010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDN1F_RS02015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDN1F_RS02020	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDN1F_RS02025	COG0200	Binds to the 23S rRNA
HDN1F_RS02040	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDN1F_RS02045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDN1F_RS02050	COG0202	RNA polymerase activity
HDN1F_RS02055	COG0203	ribosomal protein L17
HDN1F_RS02105	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HDN1F_RS02115	COG0514	ATP-dependent DNA helicase (RecQ)
HDN1F_RS02125	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDN1F_RS02145	COG1040	competence protein
HDN1F_RS02150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HDN1F_RS02155	COG0156	8-amino-7-oxononanoate synthase activity
HDN1F_RS02160	COG0596	Alpha beta hydrolase
HDN1F_RS02175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HDN1F_RS02180	COG0277	FAD linked oxidase domain protein
HDN1F_RS02185	COG0179	Fumarylacetoacetate (FAA) hydrolase
HDN1F_RS02195	COG2207	Transcriptional regulator
HDN1F_RS02200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDN1F_RS02210	COG4191	Histidine kinase
HDN1F_RS02230	COG0436	Aminotransferase
HDN1F_RS02240	COG0330	HflC and HflK could
HDN1F_RS02260	COG1234	tRNA 3'-trailer cleavage
HDN1F_RS02275	COG5001	Diguanylate cyclase
HDN1F_RS02275	COG4251	negative regulation of phosphorylation
HDN1F_RS02275	COG3706	GGDEF domain
HDN1F_RS02275	COG2203	Gaf domain
HDN1F_RS02280	COG0321	lipoyl(octanoyl) transferase activity
HDN1F_RS02290	COG1686	Belongs to the peptidase S11 family
HDN1F_RS02300	COG2951	lytic endotransglycosylase activity
HDN1F_RS02305	COG0772	Belongs to the SEDS family
HDN1F_RS02310	COG0768	penicillin binding
HDN1F_RS02315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDN1F_RS02325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDN1F_RS02330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDN1F_RS02390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDN1F_RS02420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDN1F_RS02425	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HDN1F_RS02435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HDN1F_RS02435	COG2124	cytochrome p450
HDN1F_RS02445	COG0243	molybdopterin cofactor binding
HDN1F_RS02450	COG1454	alcohol dehydrogenase
HDN1F_RS02460	COG0840	transmembrane signaling receptor activity
HDN1F_RS02465	COG2832	Protein of unknown function (DUF454)
HDN1F_RS02630	COG1136	(ABC) transporter
HDN1F_RS02640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HDN1F_RS02655	COG1561	YicC-like family, N-terminal region
HDN1F_RS02660	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HDN1F_RS02665	COG0708	Exodeoxyribonuclease III
HDN1F_RS02680	COG1309	transcriptional regulator
HDN1F_RS02685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HDN1F_RS02700	COG2003	Belongs to the UPF0758 family
HDN1F_RS02705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HDN1F_RS02710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HDN1F_RS02715	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HDN1F_RS02745	COG0494	nUDIX hydrolase
HDN1F_RS02765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HDN1F_RS02765	COG2146	nitrite reductase [NAD(P)H] activity
HDN1F_RS02775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDN1F_RS02780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HDN1F_RS02795	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HDN1F_RS02800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HDN1F_RS02840	COG1181	Belongs to the D-alanine--D-alanine ligase family
HDN1F_RS02845	COG0726	polysaccharide deacetylase
HDN1F_RS02880	COG2755	lipolytic protein G-D-S-L family
HDN1F_RS02880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HDN1F_RS02885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDN1F_RS02890	COG1132	(ABC) transporter
HDN1F_RS02905	COG1216	Glycosyl transferase, family 2
HDN1F_RS02910	COG3108	Peptidase M15
HDN1F_RS02915	COG2989	Protein conserved in bacteria
HDN1F_RS02930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HDN1F_RS02955	COG0420	3'-5' exonuclease activity
HDN1F_RS02960	COG0500	methyltransferase
HDN1F_RS02975	COG3038	cytochrome b561
HDN1F_RS02980	COG2353	YceI-like domain
HDN1F_RS02985	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HDN1F_RS02990	COG2198	Histidine kinase
HDN1F_RS02990	COG0643	Histidine kinase
HDN1F_RS03000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HDN1F_RS03005	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HDN1F_RS03010	COG2009	succinate dehydrogenase
HDN1F_RS03015	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HDN1F_RS03020	COG1053	succinate dehydrogenase
HDN1F_RS03025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HDN1F_RS03035	COG2076	Multidrug Resistance protein
HDN1F_RS03045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HDN1F_RS03110	COG0463	Glycosyl transferase, family 2
HDN1F_RS03110	COG1216	Glycosyl transferase, family 2
HDN1F_RS03125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HDN1F_RS03145	COG4372	Transposase
HDN1F_RS03150	COG3436	PFAM IS66 Orf2 family protein
HDN1F_RS03165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDN1F_RS03170	COG0154	amidase activity
HDN1F_RS03175	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDN1F_RS03180	COG1077	Cell shape determining protein MreB Mrl
HDN1F_RS03185	COG1792	Involved in formation and maintenance of cell shape
HDN1F_RS03190	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HDN1F_RS03195	COG0424	maF-like protein
HDN1F_RS03210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HDN1F_RS03215	COG3028	Belongs to the UPF0307 family
HDN1F_RS03225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HDN1F_RS03230	COG1660	Displays ATPase and GTPase activities
HDN1F_RS03240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HDN1F_RS03245	COG1137	ATPase activity
HDN1F_RS03250	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HDN1F_RS03265	COG1127	ABC transporter
HDN1F_RS03270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HDN1F_RS03275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HDN1F_RS03285	COG0271	Belongs to the BolA IbaG family
HDN1F_RS03290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDN1F_RS03295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HDN1F_RS03300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDN1F_RS03305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDN1F_RS03320	COG2046	Belongs to the sulfate adenylyltransferase family
HDN1F_RS03325	COG0071	Belongs to the small heat shock protein (HSP20) family
HDN1F_RS03335	COG2945	thiolester hydrolase activity
HDN1F_RS03340	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HDN1F_RS03345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDN1F_RS03350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HDN1F_RS03355	COG0723	plastoquinol--plastocyanin reductase activity
HDN1F_RS03360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HDN1F_RS03365	COG2857	Cytochrome c1
HDN1F_RS03370	COG2969	positive regulation of protein catabolic process
HDN1F_RS03375	COG2823	Periplasmic or secreted lipoprotein
HDN1F_RS03380	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HDN1F_RS03390	COG0792	nuclease activity
HDN1F_RS03395	COG3107	peptidoglycan biosynthetic process
HDN1F_RS03400	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDN1F_RS03410	COG0275	rRNA processing
HDN1F_RS03415	COG3116	cell division
HDN1F_RS03430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDN1F_RS03435	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDN1F_RS03440	COG0772	Belongs to the SEDS family
HDN1F_RS03445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDN1F_RS03450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HDN1F_RS03470	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HDN1F_RS03480	COG0653	protein targeting
HDN1F_RS03485	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDN1F_RS03490	COG0494	nUDIX hydrolase
HDN1F_RS03525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HDN1F_RS03535	COG0488	(ABC) transporter
HDN1F_RS03545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HDN1F_RS03555	COG0438	transferase activity, transferring glycosyl groups
HDN1F_RS03585	COG4633	Protein conserved in bacteria
HDN1F_RS03600	COG2119	membrane
HDN1F_RS03605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDN1F_RS03610	COG1111	helicase
HDN1F_RS03610	COG1205	dead DEAH box helicase
HDN1F_RS03615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HDN1F_RS03630	COG3177	Filamentation induced by cAMP protein fic
HDN1F_RS03665	COG0582	viral genome integration into host DNA
HDN1F_RS03685	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HDN1F_RS03690	COG1194	a g-specific adenine glycosylase
HDN1F_RS03700	COG0131	Imidazoleglycerol-phosphate dehydratase
HDN1F_RS03705	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDN1F_RS03710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDN1F_RS03715	COG0107	imidazoleglycerol-phosphate synthase activity
HDN1F_RS03720	COG0793	Belongs to the peptidase S41A family
HDN1F_RS03735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDN1F_RS03745	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HDN1F_RS03750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HDN1F_RS03770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDN1F_RS03770	COG0425	Belongs to the sulfur carrier protein TusA family
HDN1F_RS03780	COG1217	gtp-binding protein TYPA
HDN1F_RS03800	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HDN1F_RS03805	COG0732	type I restriction modification DNA specificity domain
HDN1F_RS03810	COG4804	nuclease activity
HDN1F_RS03815	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HDN1F_RS03840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HDN1F_RS03845	COG0439	Biotin carboxylase
HDN1F_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS03865	COG4109	DRTGG domain
HDN1F_RS03875	COG1203	CRISPR-associated helicase, Cas3
HDN1F_RS03890	COG1857	crispr-associated protein
HDN1F_RS03910	COG1518	maintenance of DNA repeat elements
HDN1F_RS03915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HDN1F_RS03935	COG0508	dehydrogenase complex catalyzes the overall conversion of
HDN1F_RS03945	COG4589	Belongs to the CDS family
HDN1F_RS03980	COG2203	Gaf domain
HDN1F_RS03980	COG4251	negative regulation of phosphorylation
HDN1F_RS03980	COG5001	Diguanylate cyclase
HDN1F_RS03980	COG3706	GGDEF domain
HDN1F_RS04005	COG1704	LemA family
HDN1F_RS04020	COG0750	zinc metalloprotease
HDN1F_RS04040	COG0840	transmembrane signaling receptor activity
HDN1F_RS04045	COG1858	cytochrome C peroxidase
HDN1F_RS04060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HDN1F_RS04085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HDN1F_RS04090	COG3101	peptidyl-lysine hydroxylation
HDN1F_RS04095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDN1F_RS04100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HDN1F_RS04120	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HDN1F_RS04120	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HDN1F_RS04145	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS04180	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HDN1F_RS04190	COG2096	Adenosyltransferase
HDN1F_RS04195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDN1F_RS04200	COG0745	RESPONSE REGULATOR receiver
HDN1F_RS04210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDN1F_RS04225	COG2264	protein methyltransferase activity
HDN1F_RS04235	COG1024	Enoyl-CoA hydratase
HDN1F_RS04255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HDN1F_RS04270	COG4804	nuclease activity
HDN1F_RS04280	COG4804	nuclease activity
HDN1F_RS04295	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HDN1F_RS04310	COG0513	Belongs to the DEAD box helicase family
HDN1F_RS04320	COG0154	amidase activity
HDN1F_RS04330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HDN1F_RS04340	COG0500	methyltransferase
HDN1F_RS04350	COG0560	Phosphoserine phosphatase
HDN1F_RS04350	COG3830	Belongs to the UPF0237 family
HDN1F_RS04370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDN1F_RS04375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HDN1F_RS04380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDN1F_RS04385	COG0149	triose-phosphate isomerase activity
HDN1F_RS04390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HDN1F_RS04405	COG0779	Required for maturation of 30S ribosomal subunits
HDN1F_RS04410	COG0195	Participates in both transcription termination and antitermination
HDN1F_RS04415	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDN1F_RS04420	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDN1F_RS04425	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDN1F_RS04430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDN1F_RS04435	COG1185	polyribonucleotide nucleotidyltransferase activity
HDN1F_RS04450	COG1466	dna polymerase III delta subunit
HDN1F_RS04460	COG0495	leucyl-tRNA aminoacylation
HDN1F_RS04465	COG0546	phosphoglycolate phosphatase activity
HDN1F_RS04470	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HDN1F_RS04475	COG4535	Mg2 and Co2 transporter CorC
HDN1F_RS04480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDN1F_RS04485	COG1702	phosphate starvation-inducible protein PhoH
HDN1F_RS04510	COG1981	membrane
HDN1F_RS04515	COG0316	Belongs to the HesB IscA family
HDN1F_RS04525	COG0739	heme binding
HDN1F_RS04530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDN1F_RS04560	COG1560	Kdo2-lipid A biosynthetic process
HDN1F_RS04570	COG0354	folic acid binding
HDN1F_RS04605	COG0501	Belongs to the peptidase M48B family
HDN1F_RS04620	COG0183	Belongs to the thiolase family
HDN1F_RS04655	COG3383	formate dehydrogenase (NAD+) activity
HDN1F_RS04680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDN1F_RS04710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDN1F_RS04720	COG0456	acetyltransferase
HDN1F_RS04725	COG0438	transferase activity, transferring glycosyl groups
HDN1F_RS04730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDN1F_RS04740	COG1090	epimerase
HDN1F_RS04765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HDN1F_RS04770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HDN1F_RS04795	COG0481	GTPase activity
HDN1F_RS04810	COG0571	ribonuclease III activity
HDN1F_RS04815	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDN1F_RS04820	COG1381	Involved in DNA repair and RecF pathway recombination
HDN1F_RS04830	COG0736	holo-[acyl-carrier-protein] synthase activity
HDN1F_RS04835	COG2205	protein histidine kinase activity
HDN1F_RS04835	COG5002	protein histidine kinase activity
HDN1F_RS04835	COG0784	Response regulator, receiver
HDN1F_RS04850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDN1F_RS04855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDN1F_RS04860	COG0521	Mo-molybdopterin cofactor biosynthetic process
HDN1F_RS04880	COG2264	protein methyltransferase activity
HDN1F_RS04890	COG0493	'glutamate synthase
HDN1F_RS04890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HDN1F_RS04895	COG0674	pyruvate-flavodoxin oxidoreductase activity
HDN1F_RS04895	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HDN1F_RS04905	COG0697	spore germination
HDN1F_RS04910	COG3047	cAMP biosynthetic process
HDN1F_RS04925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDN1F_RS04930	COG0494	nUDIX hydrolase
HDN1F_RS04935	COG3151	Protein conserved in bacteria
HDN1F_RS04940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HDN1F_RS04945	COG0133	tryptophan synthase activity
HDN1F_RS04950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HDN1F_RS04960	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HDN1F_RS04965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDN1F_RS04980	COG1546	Belongs to the CinA family
HDN1F_RS05000	COG4149	molybdate abc transporter
HDN1F_RS05005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HDN1F_RS05010	COG4771	TonB-dependent receptor
HDN1F_RS05025	COG0300	oxidoreductase activity
HDN1F_RS05050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HDN1F_RS05060	COG1181	Belongs to the D-alanine--D-alanine ligase family
HDN1F_RS05075	COG0697	spore germination
HDN1F_RS05090	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS05110	COG3321	synthase
HDN1F_RS05110	COG0300	oxidoreductase activity
HDN1F_RS05110	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS05110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HDN1F_RS05110	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS05160	COG1024	Enoyl-CoA hydratase
HDN1F_RS05160	COG1250	3-hydroxyacyl-CoA dehydrogenase
HDN1F_RS05165	COG0183	Belongs to the thiolase family
HDN1F_RS05180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HDN1F_RS05190	COG2350	Protein conserved in bacteria
HDN1F_RS05195	COG2917	probably involved in intracellular septation
HDN1F_RS05205	COG0613	PHP domain protein
HDN1F_RS05210	COG0009	L-threonylcarbamoyladenylate synthase
HDN1F_RS05220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDN1F_RS05240	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS05250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDN1F_RS05260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDN1F_RS05265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HDN1F_RS05270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HDN1F_RS05285	COG1538	Outer membrane efflux protein
HDN1F_RS05320	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS05330	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS05345	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HDN1F_RS05355	COG1555	photosystem II stabilization
HDN1F_RS05360	COG2854	intermembrane phospholipid transfer
HDN1F_RS05365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDN1F_RS05370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HDN1F_RS05420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDN1F_RS05425	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HDN1F_RS05430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDN1F_RS05435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDN1F_RS05440	COG0072	phenylalanine-tRNA ligase activity
HDN1F_RS05480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HDN1F_RS05490	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS05495	COG4770	biotin carboxylase activity
HDN1F_RS05500	COG1024	Enoyl-CoA hydratase
HDN1F_RS05505	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS05510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDN1F_RS05585	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDN1F_RS05590	COG4948	Mandelate Racemase Muconate Lactonizing
HDN1F_RS05595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDN1F_RS05600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HDN1F_RS05605	COG5001	Diguanylate cyclase
HDN1F_RS05605	COG3300	MHYT domain
HDN1F_RS05620	COG0308	aminopeptidase N
HDN1F_RS05635	COG2409	Drug exporters of the RND superfamily
HDN1F_RS05650	COG2199	diguanylate cyclase activity
HDN1F_RS05660	COG1024	Enoyl-CoA hydratase
HDN1F_RS05670	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HDN1F_RS05700	COG2124	cytochrome p450
HDN1F_RS05730	COG2137	regulation of response to DNA damage stimulus
HDN1F_RS05740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDN1F_RS05745	COG0527	aspartate kinase activity
HDN1F_RS05750	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HDN1F_RS05785	COG1278	Cold shock
HDN1F_RS05800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HDN1F_RS05805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HDN1F_RS05810	COG0705	Rhomboid family
HDN1F_RS05815	COG2356	endonuclease I
HDN1F_RS05865	COG0784	Response regulator, receiver
HDN1F_RS05865	COG0835	chemotaxis
HDN1F_RS05875	COG1815	bacterial-type flagellum-dependent cell motility
HDN1F_RS05885	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HDN1F_RS05910	COG2176	DNA-directed DNA polymerase activity
HDN1F_RS06045	COG0778	Nitroreductase
HDN1F_RS06060	COG1024	Enoyl-CoA hydratase
HDN1F_RS06075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HDN1F_RS06085	COG0709	Synthesizes selenophosphate from selenide and ATP
HDN1F_RS06095	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HDN1F_RS06100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDN1F_RS06110	COG0189	ligase activity
HDN1F_RS06110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDN1F_RS06130	COG2217	Heavy metal translocating P-type atpase
HDN1F_RS06140	COG0348	domain, Protein
HDN1F_RS06145	COG2010	Cytochrome c
HDN1F_RS06160	COG3278	Belongs to the heme-copper respiratory oxidase family
HDN1F_RS06170	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HDN1F_RS06175	COG2814	Major facilitator Superfamily
HDN1F_RS06180	COG0425	Belongs to the sulfur carrier protein TusA family
HDN1F_RS06190	COG0753	catalase activity
HDN1F_RS06315	COG0659	secondary active sulfate transmembrane transporter activity
HDN1F_RS06340	COG2862	Uncharacterized protein family, UPF0114
HDN1F_RS06350	COG0534	Mate efflux family protein
HDN1F_RS06355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HDN1F_RS06380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HDN1F_RS06410	COG4787	bacterial-type flagellum-dependent cell motility
HDN1F_RS06415	COG4786	Flagellar basal body rod
HDN1F_RS06420	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HDN1F_RS06460	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS06465	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS06495	COG0587	DNA-directed DNA polymerase activity
HDN1F_RS06510	COG0306	phosphate transporter
HDN1F_RS06515	COG0840	transmembrane signaling receptor activity
HDN1F_RS06515	COG5278	phosphoserine phosphatase activity
HDN1F_RS06535	COG0392	lysyltransferase activity
HDN1F_RS06535	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDN1F_RS06545	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HDN1F_RS06550	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HDN1F_RS06560	COG2943	transferase activity, transferring hexosyl groups
HDN1F_RS06570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HDN1F_RS06580	COG0589	response to stress
HDN1F_RS06605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDN1F_RS06620	COG1472	Belongs to the glycosyl hydrolase 3 family
HDN1F_RS06625	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HDN1F_RS06635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDN1F_RS06645	COG3118	belongs to the thioredoxin family
HDN1F_RS06655	COG2199	diguanylate cyclase activity
HDN1F_RS06655	COG2203	Gaf domain
HDN1F_RS06700	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HDN1F_RS06715	COG3148	PFAM DTW domain containing protein
HDN1F_RS06770	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS06775	COG2197	response regulator
HDN1F_RS06780	COG3850	Histidine kinase
HDN1F_RS06795	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDN1F_RS06800	COG1140	nitrate reductase beta subunit
HDN1F_RS06805	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HDN1F_RS06810	COG2181	nitrate reductase activity
HDN1F_RS06820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HDN1F_RS06825	COG0288	reversible hydration of carbon dioxide
HDN1F_RS06840	COG5002	protein histidine kinase activity
HDN1F_RS06840	COG2205	protein histidine kinase activity
HDN1F_RS06840	COG0784	Response regulator, receiver
HDN1F_RS06850	COG0189	ligase activity
HDN1F_RS06855	COG4067	protein conserved in archaea
HDN1F_RS06855	COG0189	ligase activity
HDN1F_RS06860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HDN1F_RS06875	COG4977	sequence-specific DNA binding
HDN1F_RS06875	COG1917	Cupin 2, conserved barrel domain protein
HDN1F_RS06885	COG0028	Belongs to the TPP enzyme family
HDN1F_RS06930	COG0443	Heat shock 70 kDa protein
HDN1F_RS06935	COG0443	Heat shock 70 kDa protein
HDN1F_RS06940	COG0436	Aminotransferase
HDN1F_RS06950	COG0386	Belongs to the glutathione peroxidase family
HDN1F_RS06965	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HDN1F_RS06970	COG2201	protein-glutamate methylesterase activity
HDN1F_RS06980	COG0840	transmembrane signaling receptor activity
HDN1F_RS06985	COG0840	transmembrane signaling receptor activity
HDN1F_RS07010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HDN1F_RS07025	COG2067	long-chain fatty acid transport protein
HDN1F_RS07035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HDN1F_RS07040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HDN1F_RS07045	COG1946	Acyl-CoA thioesterase
HDN1F_RS07070	COG1309	transcriptional regulator
HDN1F_RS07085	COG0189	ligase activity
HDN1F_RS07085	COG4067	protein conserved in archaea
HDN1F_RS07095	COG2272	Belongs to the type-B carboxylesterase lipase family
HDN1F_RS07100	COG0142	geranyltranstransferase activity
HDN1F_RS07105	COG1082	Xylose isomerase domain protein TIM barrel
HDN1F_RS07110	COG1854	S-ribosylhomocysteine lyase activity
HDN1F_RS07120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HDN1F_RS07140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HDN1F_RS07150	COG0531	amino acid
HDN1F_RS07170	COG3344	reverse transcriptase
HDN1F_RS07190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDN1F_RS07195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HDN1F_RS07205	COG0784	Response regulator, receiver
HDN1F_RS07205	COG2205	protein histidine kinase activity
HDN1F_RS07235	COG0745	RESPONSE REGULATOR receiver
HDN1F_RS07240	COG2205	protein histidine kinase activity
HDN1F_RS07270	COG0189	ligase activity
HDN1F_RS07275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDN1F_RS07280	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HDN1F_RS07290	COG2010	Cytochrome c
HDN1F_RS07290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HDN1F_RS07305	COG0004	ammonium transporteR
HDN1F_RS07310	COG0347	Belongs to the P(II) protein family
HDN1F_RS07320	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS07335	COG1444	tRNA N-acetyltransferase activity
HDN1F_RS07340	COG1937	Protein conserved in bacteria
HDN1F_RS07345	COG2949	membrane
HDN1F_RS07350	COG1196	nuclear chromosome segregation
HDN1F_RS07350	COG3264	Mechanosensitive ion channel
HDN1F_RS07360	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS07385	COG3307	-O-antigen
HDN1F_RS07410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HDN1F_RS07415	COG1643	Atp-dependent helicase
HDN1F_RS07435	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS07450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HDN1F_RS07480	COG4413	Urea transporter
HDN1F_RS07495	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS07500	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS07515	COG0516	GMP reductase activity
HDN1F_RS07520	COG0826	peptidase U32
HDN1F_RS07565	COG1987	bacterial-type flagellum assembly
HDN1F_RS07610	COG0784	Response regulator, receiver
HDN1F_RS07610	COG0643	Histidine kinase
HDN1F_RS07610	COG2198	Histidine kinase
HDN1F_RS07615	COG2201	protein-glutamate methylesterase activity
HDN1F_RS07620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HDN1F_RS07625	COG1360	Flagellar Motor Protein
HDN1F_RS07630	COG1192	Involved in chromosome partitioning
HDN1F_RS07640	COG0835	chemotaxis
HDN1F_RS07645	COG0835	chemotaxis
HDN1F_RS07655	COG2257	FlhB HrpN YscU SpaS Family
HDN1F_RS07665	COG4133	protoheme IX ABC transporter activity
HDN1F_RS07685	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HDN1F_RS07710	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HDN1F_RS07715	COG0788	formyltetrahydrofolate deformylase activity
HDN1F_RS07720	COG0469	pyruvate kinase activity
HDN1F_RS07725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HDN1F_RS07730	COG1132	(ABC) transporter
HDN1F_RS07735	COG1132	(ABC) transporter
HDN1F_RS07740	COG0084	hydrolase, TatD family'
HDN1F_RS07760	COG1538	Outer membrane efflux protein
HDN1F_RS07795	COG4804	nuclease activity
HDN1F_RS07825	COG1396	sequence-specific DNA binding
HDN1F_RS07845	COG0754	glutathionylspermidine amidase activity
HDN1F_RS07910	COG0515	serine threonine protein kinase
HDN1F_RS07945	COG4964	Belongs to the GSP D family
HDN1F_RS07990	COG2084	Dehydrogenase
HDN1F_RS08015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HDN1F_RS08020	COG0045	succinate-CoA ligase (ADP-forming) activity
HDN1F_RS08045	COG1278	Cold shock
HDN1F_RS08050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HDN1F_RS08055	COG0542	response to heat
HDN1F_RS08060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDN1F_RS08065	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HDN1F_RS08070	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HDN1F_RS08075	COG0492	ferredoxin-NADP+ reductase activity
HDN1F_RS08090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HDN1F_RS08095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDN1F_RS08100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDN1F_RS08105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HDN1F_RS08105	COG1648	precorrin-2 dehydrogenase activity
HDN1F_RS08130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HDN1F_RS08150	COG0326	Molecular chaperone. Has ATPase activity
HDN1F_RS08155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HDN1F_RS08170	COG1022	Amp-dependent synthetase and ligase
HDN1F_RS08180	COG0508	dehydrogenase complex catalyzes the overall conversion of
HDN1F_RS08180	COG0596	Alpha beta hydrolase
HDN1F_RS08200	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HDN1F_RS08200	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HDN1F_RS08205	COG2030	dehydratase
HDN1F_RS08225	COG2890	protein-(glutamine-N5) methyltransferase activity
HDN1F_RS08230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDN1F_RS08235	COG2814	Major facilitator Superfamily
HDN1F_RS08245	COG3609	addiction module antidote protein, CC2985 family
HDN1F_RS08260	COG3123	guanosine phosphorylase activity
HDN1F_RS08270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDN1F_RS08275	COG0589	response to stress
HDN1F_RS08280	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HDN1F_RS08285	COG3657	addiction module killer protein
HDN1F_RS08290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDN1F_RS08295	COG0066	3-isopropylmalate dehydratase activity
HDN1F_RS08300	COG0473	3-isopropylmalate dehydrogenase activity
HDN1F_RS08305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDN1F_RS08330	COG0135	phosphoribosylanthranilate isomerase activity
HDN1F_RS08340	COG0159	tryptophan synthase activity
HDN1F_RS08345	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDN1F_RS08350	COG0285	dihydrofolate synthase activity
HDN1F_RS08360	COG1286	toxin biosynthetic process
HDN1F_RS08375	COG0714	Associated with various cellular activities
HDN1F_RS08395	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HDN1F_RS08410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDN1F_RS08440	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HDN1F_RS08445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDN1F_RS08450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDN1F_RS08470	COG0544	peptidyl-prolyl cis-trans isomerase activity
HDN1F_RS08475	COG0740	serine-type endopeptidase activity
HDN1F_RS08480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDN1F_RS08485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HDN1F_RS08500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HDN1F_RS08505	COG4172	Belongs to the ABC transporter superfamily
HDN1F_RS08510	COG4239	(ABC) transporter, permease
HDN1F_RS08515	COG4174	ABC transporter (Permease)
HDN1F_RS08520	COG4166	transmembrane transport
HDN1F_RS08525	COG4166	transmembrane transport
HDN1F_RS08535	COG1388	LysM domain
HDN1F_RS08535	COG0741	lytic transglycosylase activity
HDN1F_RS08540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HDN1F_RS08545	COG2226	methyltransferase
HDN1F_RS08550	COG0328	RNA-DNA hybrid ribonuclease activity
HDN1F_RS08555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HDN1F_RS08575	COG0616	signal peptide processing
HDN1F_RS08585	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HDN1F_RS08585	COG0316	Belongs to the HesB IscA family
HDN1F_RS08590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HDN1F_RS08610	COG0589	response to stress
HDN1F_RS08630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDN1F_RS08635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HDN1F_RS08645	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HDN1F_RS08655	COG5002	protein histidine kinase activity
HDN1F_RS08655	COG5001	Diguanylate cyclase
HDN1F_RS08665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDN1F_RS08705	COG1346	cytolysis
HDN1F_RS08715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HDN1F_RS08725	COG2885	chlorophyll binding
HDN1F_RS08780	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS08835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HDN1F_RS08835	COG4651	solute:proton antiporter activity
HDN1F_RS08855	COG4644	lycopene metabolic process
HDN1F_RS08925	COG3311	Transcriptional regulator
HDN1F_RS08930	COG1569	PIN domain
HDN1F_RS08960	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS08965	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS09030	COG0633	Ferredoxin
HDN1F_RS09070	COG1192	Involved in chromosome partitioning
HDN1F_RS09140	COG2003	Belongs to the UPF0758 family
HDN1F_RS09160	COG2944	sequence-specific DNA binding
HDN1F_RS09195	COG3344	reverse transcriptase
HDN1F_RS09360	COG4974	Belongs to the 'phage' integrase family
HDN1F_RS09380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDN1F_RS09385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HDN1F_RS09395	COG2010	Cytochrome c
HDN1F_RS09425	COG4191	Histidine kinase
HDN1F_RS09435	COG2391	methyltransferase activity
HDN1F_RS09440	COG0425	Belongs to the sulfur carrier protein TusA family
HDN1F_RS09445	COG0583	DNA-binding transcription factor activity
HDN1F_RS09455	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HDN1F_RS09485	COG0012	GTP binding
HDN1F_RS09490	COG0193	aminoacyl-tRNA hydrolase activity
HDN1F_RS09495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HDN1F_RS09500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDN1F_RS09510	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDN1F_RS09515	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HDN1F_RS09540	COG4691	Plasmid stability protein
HDN1F_RS09545	COG1487	ribonuclease activity
HDN1F_RS09550	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HDN1F_RS09555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDN1F_RS09565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HDN1F_RS09570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS09575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS09580	COG0649	NAD binding
HDN1F_RS09580	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS09585	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HDN1F_RS09605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS09610	COG0839	Belongs to the complex I subunit 6 family
HDN1F_RS09615	COG0713	ATP synthesis coupled electron transport
HDN1F_RS09630	COG1007	ATP synthesis coupled electron transport
HDN1F_RS09640	COG0514	ATP-dependent DNA helicase (RecQ)
HDN1F_RS09645	COG2199	diguanylate cyclase activity
HDN1F_RS09645	COG3287	FIST C domain
HDN1F_RS09645	COG2200	EAL domain
HDN1F_RS09655	COG1509	lysine 2,3-aminomutase activity
HDN1F_RS09660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDN1F_RS09680	COG5640	endopeptidase activity
HDN1F_RS09685	COG0688	phosphatidylethanolamine metabolic process
HDN1F_RS09700	COG1360	Flagellar Motor Protein
HDN1F_RS09705	COG1162	GTPase activity
HDN1F_RS09715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HDN1F_RS09715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDN1F_RS09720	COG0802	atpase or kinase
HDN1F_RS09730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDN1F_RS09735	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HDN1F_RS09745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HDN1F_RS09750	COG1011	Hydrolase
HDN1F_RS09755	COG0494	nUDIX hydrolase
HDN1F_RS09760	COG1218	3'(2'),5'-bisphosphate nucleotidase
HDN1F_RS09765	COG0529	Catalyzes the synthesis of activated sulfate
HDN1F_RS09785	COG0583	DNA-binding transcription factor activity
HDN1F_RS09810	COG4191	Histidine kinase
HDN1F_RS09815	COG4566	intracellular signal transduction
HDN1F_RS09820	COG2198	Histidine kinase
HDN1F_RS09820	COG0643	Histidine kinase
HDN1F_RS09825	COG0840	transmembrane signaling receptor activity
HDN1F_RS09830	COG0835	chemotaxis
HDN1F_RS09840	COG4399	Belongs to the UPF0754 family
HDN1F_RS09885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HDN1F_RS09960	COG3436	PFAM IS66 Orf2 family protein
HDN1F_RS09965	COG4372	Transposase
HDN1F_RS09995	COG0742	ribosomal rna small subunit methyltransferase
HDN1F_RS10000	COG0612	Peptidase, M16
HDN1F_RS10005	COG0612	Peptidase, M16
HDN1F_RS10015	COG0552	protein localization to endoplasmic reticulum
HDN1F_RS10020	COG2884	Cell division ATP-binding protein ftsE
HDN1F_RS10025	COG2177	Part of the ABC transporter FtsEX involved in
HDN1F_RS10075	COG0515	serine threonine protein kinase
HDN1F_RS10080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDN1F_RS10085	COG0583	DNA-binding transcription factor activity
HDN1F_RS10090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDN1F_RS10095	COG2982	Protein involved in outer membrane biogenesis
HDN1F_RS10100	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HDN1F_RS10100	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HDN1F_RS10125	COG2124	cytochrome p450
HDN1F_RS10135	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS10140	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS10145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HDN1F_RS10160	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS10190	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS10195	COG3976	FMN-binding domain protein
HDN1F_RS10195	COG1053	succinate dehydrogenase
HDN1F_RS10200	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS10225	COG2151	metal-sulfur cluster biosynthetic enzyme
HDN1F_RS10250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HDN1F_RS10255	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HDN1F_RS10260	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HDN1F_RS10265	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HDN1F_RS10270	COG0617	tRNA 3'-terminal CCA addition
HDN1F_RS10305	COG0243	molybdopterin cofactor binding
HDN1F_RS10310	COG1140	nitrate reductase beta subunit
HDN1F_RS10315	COG2010	Cytochrome c
HDN1F_RS10325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HDN1F_RS10335	COG4372	Transposase
HDN1F_RS10340	COG3436	PFAM IS66 Orf2 family protein
HDN1F_RS10350	COG2198	Histidine kinase
HDN1F_RS10350	COG0643	Histidine kinase
HDN1F_RS10355	COG0259	pyridoxamine-phosphate oxidase activity
HDN1F_RS10370	COG4794	Type iii secretion
HDN1F_RS10375	COG4790	Type iii secretion
HDN1F_RS10380	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HDN1F_RS10385	COG4566	intracellular signal transduction
HDN1F_RS10390	COG4191	Histidine kinase
HDN1F_RS10455	COG0473	3-isopropylmalate dehydrogenase activity
HDN1F_RS10460	COG0288	reversible hydration of carbon dioxide
HDN1F_RS10495	COG3604	Transcriptional regulator
HDN1F_RS10520	COG1959	2 iron, 2 sulfur cluster binding
HDN1F_RS10530	COG2813	Specifically methylates the guanine in position
HDN1F_RS10535	COG1187	pseudouridine synthase activity
HDN1F_RS10555	COG0745	RESPONSE REGULATOR receiver
HDN1F_RS10570	COG0280	phosphate acetyltransferase
HDN1F_RS10570	COG0281	malic enzyme
HDN1F_RS10575	COG0861	Integral membrane protein TerC family
HDN1F_RS10590	COG2205	protein histidine kinase activity
HDN1F_RS10590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HDN1F_RS10595	COG2205	protein histidine kinase activity
HDN1F_RS10595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HDN1F_RS10595	COG2198	Histidine kinase
HDN1F_RS10595	COG0784	Response regulator, receiver
HDN1F_RS10600	COG0784	Response regulator, receiver
HDN1F_RS10600	COG5002	protein histidine kinase activity
HDN1F_RS10600	COG2205	protein histidine kinase activity
HDN1F_RS10615	COG2154	pterin-4-alpha-carbinolamine dehydratase
HDN1F_RS10620	COG1047	Peptidyl-prolyl cis-trans
HDN1F_RS10630	COG1490	D-aminoacyl-tRNA deacylase activity
HDN1F_RS10635	COG2719	SpoVR family
HDN1F_RS10640	COG2718	Belongs to the UPF0229 family
HDN1F_RS10645	COG2766	serine protein kinase
HDN1F_RS10650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HDN1F_RS10660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HDN1F_RS10665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HDN1F_RS10670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HDN1F_RS10675	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HDN1F_RS10685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HDN1F_RS10690	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HDN1F_RS10745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HDN1F_RS10750	COG0546	phosphoglycolate phosphatase activity
HDN1F_RS10760	COG1002	Type II restriction enzyme, methylase subunits
HDN1F_RS10770	COG4804	nuclease activity
HDN1F_RS10775	COG1061	Type III restriction enzyme res subunit
HDN1F_RS10780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HDN1F_RS10810	COG0512	Glutamine amidotransferase of anthranilate synthase
HDN1F_RS10830	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDN1F_RS10835	COG1923	regulation of RNA biosynthetic process
HDN1F_RS10840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDN1F_RS10845	COG0330	HflC and HflK could
HDN1F_RS10850	COG0330	HflC and HflK could
HDN1F_RS10890	COG2166	iron-sulfur cluster assembly
HDN1F_RS10895	COG2151	metal-sulfur cluster biosynthetic enzyme
HDN1F_RS10900	COG0316	Belongs to the HesB IscA family
HDN1F_RS10905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDN1F_RS10915	COG0396	ATPase activity
HDN1F_RS10920	COG0719	Fe-S assembly protein
HDN1F_RS10925	COG1959	2 iron, 2 sulfur cluster binding
HDN1F_RS10945	COG0534	Mate efflux family protein
HDN1F_RS10955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDN1F_RS10960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDN1F_RS11015	COG1309	transcriptional regulator
HDN1F_RS11020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDN1F_RS11025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDN1F_RS11060	COG0795	lipopolysaccharide-transporting ATPase activity
HDN1F_RS11065	COG0795	lipopolysaccharide-transporting ATPase activity
HDN1F_RS11080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDN1F_RS11085	COG0343	queuine tRNA-ribosyltransferase activity
HDN1F_RS11090	COG1862	Preprotein translocase
HDN1F_RS11100	COG4399	Belongs to the UPF0754 family
HDN1F_RS11130	COG1104	cysteine desulfurase activity
HDN1F_RS11140	COG0105	UTP biosynthetic process
HDN1F_RS11145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HDN1F_RS11160	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HDN1F_RS11165	COG0124	histidyl-tRNA synthetase
HDN1F_RS11170	COG2976	Protein conserved in bacteria
HDN1F_RS11180	COG1160	GTP binding
HDN1F_RS11255	COG1404	Belongs to the peptidase S8 family
HDN1F_RS11275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HDN1F_RS11280	COG2204	response regulator
HDN1F_RS11285	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS11310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HDN1F_RS11315	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS11325	COG0519	Catalyzes the synthesis of GMP from XMP
HDN1F_RS11325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HDN1F_RS11330	COG1196	nuclear chromosome segregation
HDN1F_RS11370	COG1595	DNA-templated transcription, initiation
HDN1F_RS11380	COG0513	Belongs to the DEAD box helicase family
HDN1F_RS11390	COG0598	Magnesium transport protein CorA
HDN1F_RS11405	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HDN1F_RS11425	COG2205	protein histidine kinase activity
HDN1F_RS11425	COG0784	Response regulator, receiver
HDN1F_RS11440	COG0494	nUDIX hydrolase
HDN1F_RS11455	COG4536	flavin adenine dinucleotide binding
HDN1F_RS11465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDN1F_RS11470	COG0228	four-way junction DNA binding
HDN1F_RS11475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDN1F_RS11480	COG0336	Belongs to the RNA methyltransferase TrmD family
HDN1F_RS11495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HDN1F_RS11505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HDN1F_RS11510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HDN1F_RS11525	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HDN1F_RS11535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDN1F_RS11540	COG0724	RNA recognition motif
HDN1F_RS11555	COG1024	Enoyl-CoA hydratase
HDN1F_RS11565	COG0778	Nitroreductase
HDN1F_RS11570	COG2755	lipolytic protein G-D-S-L family
HDN1F_RS11570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HDN1F_RS11595	COG0745	RESPONSE REGULATOR receiver
HDN1F_RS11610	COG0581	inorganic phosphate transmembrane transporter activity
HDN1F_RS11615	COG0573	inorganic phosphate transmembrane transporter activity
HDN1F_RS11630	COG2814	Major facilitator Superfamily
HDN1F_RS11635	COG1566	PFAM secretion protein HlyD family protein
HDN1F_RS11640	COG1846	Transcriptional regulator
HDN1F_RS11650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HDN1F_RS11660	COG2226	methyltransferase
HDN1F_RS11675	COG4221	oxidoreductase activity
HDN1F_RS11680	COG1064	alcohol dehydrogenase
HDN1F_RS11700	COG1943	Transposase
HDN1F_RS11715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HDN1F_RS11780	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HDN1F_RS11785	COG2914	Belongs to the UPF0125 (RnfH) family
HDN1F_RS11800	COG0497	DNA recombination
HDN1F_RS11830	COG4279	zinc finger
HDN1F_RS11835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HDN1F_RS11860	COG1420	regulation of RNA biosynthetic process
HDN1F_RS11865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDN1F_RS11870	COG0443	Heat shock 70 kDa protein
HDN1F_RS11875	COG0484	heat shock protein binding
HDN1F_RS11880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HDN1F_RS11895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HDN1F_RS11940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDN1F_RS11945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDN1F_RS11955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HDN1F_RS11970	COG2026	Addiction module toxin, RelE StbE family
HDN1F_RS11980	COG0586	Pfam SNARE associated Golgi protein
HDN1F_RS12020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDN1F_RS12025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDN1F_RS12030	COG0140	phosphoribosyl-ATP diphosphatase activity
HDN1F_RS12035	COG2226	methyltransferase
HDN1F_RS12045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDN1F_RS12050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDN1F_RS12060	COG0018	arginyl-trna synthetase
HDN1F_RS12085	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HDN1F_RS12090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDN1F_RS12115	COG2274	protein secretion by the type I secretion system
HDN1F_RS12140	COG0557	exoribonuclease II activity
HDN1F_RS12145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDN1F_RS12150	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HDN1F_RS12165	COG5445	Predicted secreted protein (DUF2300)
HDN1F_RS12170	COG4676	Protein conserved in bacteria
HDN1F_RS12175	COG4792	protein secretion
HDN1F_RS12200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDN1F_RS12210	COG0359	binds to the 23S rRNA
HDN1F_RS12250	COG1805	sodium ion transport
HDN1F_RS12265	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HDN1F_RS12275	COG1477	protein flavinylation
HDN1F_RS12290	COG0305	Participates in initiation and elongation during chromosome replication
HDN1F_RS12295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDN1F_RS12330	COG2995	paraquat-inducible protein a
HDN1F_RS12335	COG2995	paraquat-inducible protein a
HDN1F_RS12340	COG3008	intermembrane lipid transfer
HDN1F_RS12350	COG0728	peptidoglycan biosynthetic process
HDN1F_RS12375	COG0589	response to stress
HDN1F_RS12405	COG5001	Diguanylate cyclase
HDN1F_RS12410	COG1595	DNA-templated transcription, initiation
HDN1F_RS12415	COG0302	gtp cyclohydrolase
HDN1F_RS12420	COG1297	OPT oligopeptide transporter protein
HDN1F_RS12450	COG1840	ABC-type Fe3 transport system, periplasmic component
HDN1F_RS12455	COG1178	ABC-type Fe3 transport system permease component
HDN1F_RS12460	COG3842	ATPase activity
HDN1F_RS12465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HDN1F_RS12480	COG0488	(ABC) transporter
HDN1F_RS12490	COG3122	Protein conserved in bacteria
HDN1F_RS12510	COG2363	Small membrane protein
HDN1F_RS12515	COG2827	Endonuclease containing a URI domain
HDN1F_RS12545	COG2951	lytic endotransglycosylase activity
HDN1F_RS12555	COG0217	transcriptional regulatory protein
HDN1F_RS12565	COG0840	transmembrane signaling receptor activity
HDN1F_RS12585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HDN1F_RS12600	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HDN1F_RS12605	COG0784	Response regulator, receiver
HDN1F_RS12605	COG2198	Histidine kinase
HDN1F_RS12605	COG2205	protein histidine kinase activity
HDN1F_RS12625	COG1132	(ABC) transporter
HDN1F_RS12660	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS12670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HDN1F_RS12705	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS12715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDN1F_RS12725	COG0204	Acyl-transferase
HDN1F_RS12755	COG2258	MOSC domain
HDN1F_RS12760	COG2863	cytochrome
HDN1F_RS12765	COG3258	Cytochrome c
HDN1F_RS12770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HDN1F_RS12795	COG2807	transmembrane transport
HDN1F_RS12805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDN1F_RS12850	COG0297	glycogen (starch) synthase activity
HDN1F_RS12850	COG0438	transferase activity, transferring glycosyl groups
HDN1F_RS12905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HDN1F_RS12910	COG0243	molybdopterin cofactor binding
HDN1F_RS12915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HDN1F_RS12925	COG2223	nitrite transmembrane transporter activity
HDN1F_RS12940	COG0840	transmembrane signaling receptor activity
HDN1F_RS12955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDN1F_RS12960	COG1393	Belongs to the ArsC family
HDN1F_RS12965	COG0025	NhaP-type Na H and K H
HDN1F_RS12975	COG2391	methyltransferase activity
HDN1F_RS12980	COG2391	methyltransferase activity
HDN1F_RS12985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDN1F_RS12990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDN1F_RS12990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDN1F_RS13005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HDN1F_RS13085	COG3119	arylsulfatase activity
HDN1F_RS13090	COG5002	protein histidine kinase activity
HDN1F_RS13095	COG0745	RESPONSE REGULATOR receiver
HDN1F_RS13115	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDN1F_RS13120	COG0463	Glycosyl transferase, family 2
HDN1F_RS13155	COG0784	Response regulator, receiver
HDN1F_RS13155	COG5002	protein histidine kinase activity
HDN1F_RS13185	COG0824	Thioesterase
HDN1F_RS13190	COG1454	alcohol dehydrogenase
HDN1F_RS13200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDN1F_RS13205	COG0142	geranyltranstransferase activity
HDN1F_RS13235	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HDN1F_RS13240	COG3657	addiction module killer protein
HDN1F_RS13255	COG1966	Carbon starvation protein
HDN1F_RS13260	COG2879	small protein
HDN1F_RS13265	COG2827	Endonuclease containing a URI domain
HDN1F_RS13275	COG4771	TonB-dependent receptor
HDN1F_RS13300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDN1F_RS13310	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HDN1F_RS13315	COG2894	cell division
HDN1F_RS13320	COG0850	regulation of cytokinetic process
HDN1F_RS13340	COG0517	IMP dehydrogenase activity
HDN1F_RS13345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS13350	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS13355	COG0649	NAD binding
HDN1F_RS13355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS13375	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HDN1F_RS13380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS13395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HDN1F_RS13400	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HDN1F_RS13405	COG1007	ATP synthesis coupled electron transport
HDN1F_RS13415	COG1797	cobyrinic acid a,c-diamide synthase activity
HDN1F_RS13435	COG2099	Precorrin-6x reductase
HDN1F_RS13475	COG1120	ATPase activity
HDN1F_RS13480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDN1F_RS13490	COG4774	siderophore transport
HDN1F_RS13500	COG0151	Belongs to the GarS family
HDN1F_RS13505	COG0138	bifunctional purine biosynthesis protein purh
HDN1F_RS13515	COG0840	transmembrane signaling receptor activity
HDN1F_RS13530	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HDN1F_RS13570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HDN1F_RS13595	COG2885	chlorophyll binding
HDN1F_RS13610	COG0840	transmembrane signaling receptor activity
HDN1F_RS13655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HDN1F_RS13660	COG4232	protein-disulfide reductase activity
HDN1F_RS13690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HDN1F_RS13700	COG1946	Acyl-CoA thioesterase
HDN1F_RS13710	COG1012	belongs to the aldehyde dehydrogenase family
HDN1F_RS13750	COG1320	monovalent cation:proton antiporter activity
HDN1F_RS13755	COG2212	antiporter activity
HDN1F_RS13760	COG1863	multisubunit Na H antiporter MnhE subunit
HDN1F_RS13765	COG0651	ATP synthesis coupled electron transport
HDN1F_RS13770	COG1006	Multisubunit Na H antiporter MnhC subunit
HDN1F_RS13775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HDN1F_RS13775	COG2111	Na H antiporter
HDN1F_RS13780	COG1283	sodium-dependent phosphate transmembrane transporter activity
HDN1F_RS13785	COG0733	neurotransmitter:sodium symporter activity
HDN1F_RS13790	COG1295	ribonuclease BN
HDN1F_RS13820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDN1F_RS13825	COG4569	acetaldehyde dehydrogenase (acetylating) activity
HDN1F_RS13845	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS13850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HDN1F_RS13875	COG2197	response regulator
HDN1F_RS13890	COG3278	Belongs to the heme-copper respiratory oxidase family
HDN1F_RS13905	COG2010	Cytochrome c
HDN1F_RS13920	COG5001	Diguanylate cyclase
HDN1F_RS13920	COG3300	MHYT domain
HDN1F_RS13940	COG3437	response regulator, receiver
HDN1F_RS13940	COG0784	Response regulator, receiver
HDN1F_RS13950	COG1994	Peptidase M50
HDN1F_RS13960	COG4804	nuclease activity
HDN1F_RS13965	COG0346	lactoylglutathione lyase activity
HDN1F_RS14000	COG1024	Enoyl-CoA hydratase
HDN1F_RS14005	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS14010	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS14015	COG0183	Belongs to the thiolase family
HDN1F_RS14020	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS14025	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS14030	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS14045	COG0840	transmembrane signaling receptor activity
HDN1F_RS14050	COG1573	uracil-dna glycosylase
HDN1F_RS14070	COG1610	YqeY-like protein
HDN1F_RS14075	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HDN1F_RS14080	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDN1F_RS14085	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HDN1F_RS14090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDN1F_RS14095	COG0302	gtp cyclohydrolase
HDN1F_RS14095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HDN1F_RS14100	COG0617	tRNA 3'-terminal CCA addition
HDN1F_RS14105	COG2226	methyltransferase
HDN1F_RS14125	COG4221	oxidoreductase activity
HDN1F_RS14140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HDN1F_RS14190	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS14195	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS14225	COG1360	Flagellar Motor Protein
HDN1F_RS14265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HDN1F_RS14295	COG0347	Belongs to the P(II) protein family
HDN1F_RS14305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HDN1F_RS14310	COG1166	arginine decarboxylase activity
HDN1F_RS14320	COG1519	Transferase
HDN1F_RS14325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HDN1F_RS14340	COG1492	cobalamin metabolic process
HDN1F_RS14350	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS14360	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDN1F_RS14375	COG5001	Diguanylate cyclase
HDN1F_RS14375	COG3300	MHYT domain
HDN1F_RS14380	COG2203	Gaf domain
HDN1F_RS14380	COG5001	Diguanylate cyclase
HDN1F_RS14380	COG3706	GGDEF domain
HDN1F_RS14380	COG4251	negative regulation of phosphorylation
HDN1F_RS14390	COG0024	Methionine aminopeptidase
HDN1F_RS14395	COG0052	Belongs to the universal ribosomal protein uS2 family
HDN1F_RS14400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDN1F_RS14405	COG0528	UMP kinase activity
HDN1F_RS14410	COG0233	cytoplasmic translational termination
HDN1F_RS14415	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDN1F_RS14425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HDN1F_RS14430	COG0750	zinc metalloprotease
HDN1F_RS14450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HDN1F_RS14455	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HDN1F_RS14460	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HDN1F_RS14465	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDN1F_RS14470	COG0587	DNA-directed DNA polymerase activity
HDN1F_RS14475	COG0825	malonyl-CoA metabolic process
HDN1F_RS14480	COG0730	response to heat
HDN1F_RS14500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HDN1F_RS14505	COG1138	Cytochrome C-type biogenesis protein
HDN1F_RS14530	COG0563	adenylate kinase activity
HDN1F_RS14535	COG0746	molybdenum cofactor guanylyltransferase activity
HDN1F_RS14540	COG1214	PFAM Peptidase M22, glycoprotease
HDN1F_RS14550	COG0742	ribosomal rna small subunit methyltransferase
HDN1F_RS14560	COG1131	(ABC) transporter
HDN1F_RS14575	COG0037	tRNA processing
HDN1F_RS14595	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HDN1F_RS14600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HDN1F_RS14610	COG0585	pseudouridine synthase activity
HDN1F_RS14615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HDN1F_RS14640	COG0519	Catalyzes the synthesis of GMP from XMP
HDN1F_RS14650	COG2198	Histidine kinase
HDN1F_RS14650	COG0784	Response regulator, receiver
HDN1F_RS14650	COG2205	protein histidine kinase activity
HDN1F_RS14655	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HDN1F_RS14660	COG1074	ATP-dependent DNA helicase activity
HDN1F_RS14665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HDN1F_RS14675	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS14680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDN1F_RS14700	COG1115	amino acid carrier protein
HDN1F_RS14715	COG4221	oxidoreductase activity
HDN1F_RS14740	COG3266	domain, Protein
HDN1F_RS14750	COG3150	esterase
HDN1F_RS14820	COG0515	serine threonine protein kinase
HDN1F_RS14820	COG2815	serine threonine protein kinase
HDN1F_RS14835	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HDN1F_RS14860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HDN1F_RS14865	COG3706	GGDEF domain
HDN1F_RS14865	COG5001	Diguanylate cyclase
HDN1F_RS14865	COG4251	negative regulation of phosphorylation
HDN1F_RS14865	COG2203	Gaf domain
HDN1F_RS14875	COG3038	cytochrome b561
HDN1F_RS14880	COG0840	transmembrane signaling receptor activity
HDN1F_RS14890	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS14900	COG0204	Acyl-transferase
HDN1F_RS14910	COG0501	Belongs to the peptidase M48B family
HDN1F_RS14915	COG1704	LemA family
HDN1F_RS14925	COG1469	GTP cyclohydrolase I activity
HDN1F_RS14935	COG1765	OsmC-like protein
HDN1F_RS14940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HDN1F_RS14945	COG0588	phosphoglycerate mutase activity
HDN1F_RS14990	COG0302	gtp cyclohydrolase
HDN1F_RS15000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDN1F_RS15005	COG0577	efflux transmembrane transporter activity
HDN1F_RS15005	COG1136	(ABC) transporter
HDN1F_RS15010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HDN1F_RS15010	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HDN1F_RS15015	COG1233	COG1233 Phytoene dehydrogenase and related
HDN1F_RS15025	COG1845	cytochrome c oxidase, subunit III
HDN1F_RS15050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HDN1F_RS15055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HDN1F_RS15060	COG0500	methyltransferase
HDN1F_RS15065	COG1131	(ABC) transporter
HDN1F_RS15070	COG0842	Transport permease protein
HDN1F_RS15075	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HDN1F_RS15075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HDN1F_RS15080	COG3268	Saccharopine dehydrogenase
HDN1F_RS15120	COG3344	reverse transcriptase
HDN1F_RS15160	COG3436	PFAM IS66 Orf2 family protein
HDN1F_RS15165	COG4372	Transposase
HDN1F_RS15190	COG3344	reverse transcriptase
HDN1F_RS15195	COG4372	Transposase
HDN1F_RS15200	COG3436	PFAM IS66 Orf2 family protein
HDN1F_RS15245	COG3344	reverse transcriptase
HDN1F_RS15315	COG3344	reverse transcriptase
HDN1F_RS15360	COG0811	peptide transport
HDN1F_RS15380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HDN1F_RS15390	COG0501	Belongs to the peptidase M48B family
HDN1F_RS15400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HDN1F_RS15405	COG2855	membrane
HDN1F_RS15410	COG0583	DNA-binding transcription factor activity
HDN1F_RS15425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDN1F_RS15435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HDN1F_RS15435	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HDN1F_RS15450	COG3134	Outer membrane lipoprotein
HDN1F_RS15465	COG0183	Belongs to the thiolase family
HDN1F_RS15470	COG1024	Enoyl-CoA hydratase
HDN1F_RS15470	COG1250	3-hydroxyacyl-CoA dehydrogenase
HDN1F_RS15500	COG0714	Associated with various cellular activities
HDN1F_RS15540	COG2124	cytochrome p450
HDN1F_RS15550	COG0471	metal ion transport
HDN1F_RS15555	COG1917	Cupin 2, conserved barrel domain protein
HDN1F_RS15570	COG1846	Transcriptional regulator
HDN1F_RS15585	COG1968	undecaprenyl-diphosphatase activity
HDN1F_RS15595	COG1304	FMN binding
HDN1F_RS15610	COG0436	Aminotransferase
HDN1F_RS15620	COG0070	glutamate synthase
HDN1F_RS15620	COG0067	glutamate synthase
HDN1F_RS15620	COG0069	glutamate synthase activity
HDN1F_RS15625	COG3609	addiction module antidote protein, CC2985 family
HDN1F_RS15645	COG3852	Histidine kinase
HDN1F_RS15650	COG0174	glutamine synthetase
HDN1F_RS15660	COG0237	dephospho-CoA kinase activity
HDN1F_RS15665	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HDN1F_RS15670	COG3657	addiction module killer protein
HDN1F_RS15700	COG4680	protein conserved in bacteria
HDN1F_RS15705	COG5499	transcription regulator containing HTH domain
HDN1F_RS15750	COG3830	Belongs to the UPF0237 family
HDN1F_RS15750	COG0560	Phosphoserine phosphatase
HDN1F_RS15755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDN1F_RS15765	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HDN1F_RS15800	COG3177	Filamentation induced by cAMP protein fic
HDN1F_RS15805	COG3344	reverse transcriptase
HDN1F_RS15820	COG0431	NADPH-dependent FMN reductase
HDN1F_RS15850	COG0840	transmembrane signaling receptor activity
HDN1F_RS15855	COG0071	Belongs to the small heat shock protein (HSP20) family
HDN1F_RS15870	COG1309	transcriptional regulator
HDN1F_RS15885	COG1136	(ABC) transporter
HDN1F_RS15930	COG1487	ribonuclease activity
HDN1F_RS15935	COG4456	Virulence-associated protein
HDN1F_RS15960	COG0167	dihydroorotate dehydrogenase activity
HDN1F_RS15975	COG2337	Toxic component of a toxin-antitoxin (TA) module
HDN1F_RS15980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HDN1F_RS15980	COG0116	Belongs to the methyltransferase superfamily
HDN1F_RS16060	COG1677	Flagellar hook-basal body complex protein FliE
HDN1F_RS16095	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HDN1F_RS16110	COG0745	RESPONSE REGULATOR receiver
HDN1F_RS16160	COG0489	protein tyrosine kinase activity
HDN1F_RS16165	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS16175	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HDN1F_RS16190	COG0028	Belongs to the TPP enzyme family
HDN1F_RS16195	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HDN1F_RS16210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HDN1F_RS16215	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HDN1F_RS16235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HDN1F_RS16245	COG2030	dehydratase
HDN1F_RS16260	COG0730	response to heat
HDN1F_RS16265	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS16275	COG1902	pentaerythritol trinitrate reductase activity
HDN1F_RS16275	COG0446	pyridine nucleotide-disulphide oxidoreductase
HDN1F_RS16280	COG0564	pseudouridine synthase activity
HDN1F_RS16285	COG0084	hydrolase, TatD family'
HDN1F_RS16305	COG1067	ATP-dependent peptidase activity
HDN1F_RS16310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDN1F_RS16360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDN1F_RS16365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDN1F_RS16370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HDN1F_RS16390	COG0840	transmembrane signaling receptor activity
HDN1F_RS16395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HDN1F_RS16405	COG0017	Asparaginyl-tRNA synthetase
HDN1F_RS16410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HDN1F_RS16420	COG0137	argininosuccinate synthase activity
HDN1F_RS16430	COG5001	Diguanylate cyclase
HDN1F_RS16435	COG2835	tetraacyldisaccharide 4'-kinase activity
HDN1F_RS16440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDN1F_RS16445	COG2878	Part of a membrane complex involved in electron transport
HDN1F_RS16450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDN1F_RS16450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDN1F_RS16455	COG0489	protein tyrosine kinase activity
HDN1F_RS16460	COG0717	Belongs to the dCTP deaminase family
HDN1F_RS16465	COG0861	Integral membrane protein TerC family
HDN1F_RS16485	COG4372	Transposase
HDN1F_RS16490	COG3436	PFAM IS66 Orf2 family protein
HDN1F_RS16505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDN1F_RS16520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDN1F_RS16525	COG2205	protein histidine kinase activity
HDN1F_RS16525	COG2198	Histidine kinase
HDN1F_RS16525	COG0784	Response regulator, receiver
HDN1F_RS16540	COG0714	Associated with various cellular activities
HDN1F_RS16570	COG1393	Belongs to the ArsC family
HDN1F_RS16590	COG3706	GGDEF domain
HDN1F_RS16595	COG0442	prolyl-tRNA aminoacylation
HDN1F_RS16605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HDN1F_RS16615	COG0632	four-way junction helicase activity
HDN1F_RS16620	COG2255	four-way junction helicase activity
HDN1F_RS16625	COG0824	Thioesterase
HDN1F_RS16645	COG0823	Involved in the tonB-independent uptake of proteins
HDN1F_RS16650	COG2885	chlorophyll binding
HDN1F_RS16660	COG0602	queuosine metabolic process
HDN1F_RS16665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HDN1F_RS16685	COG4783	chaperone-mediated protein folding
HDN1F_RS16690	COG0425	Belongs to the sulfur carrier protein TusA family
HDN1F_RS16700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HDN1F_RS16705	COG2716	regulation of RNA biosynthetic process
HDN1F_RS16720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HDN1F_RS16740	COG1309	transcriptional regulator
HDN1F_RS16750	COG1805	sodium ion transport
HDN1F_RS16765	COG0584	glycerophosphoryl diester phosphodiesterase
HDN1F_RS16770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HDN1F_RS16785	COG4591	ABC-type transport system involved in lipoprotein release permease component
HDN1F_RS16800	COG0811	peptide transport
HDN1F_RS16805	COG0848	biopolymer transport protein
HDN1F_RS16810	COG1663	tetraacyldisaccharide 4'-kinase activity
HDN1F_RS16815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HDN1F_RS16820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDN1F_RS16825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HDN1F_RS16830	COG1530	ribonuclease E activity
HDN1F_RS16835	COG0564	pseudouridine synthase activity
HDN1F_RS16840	COG0546	phosphoglycolate phosphatase activity
HDN1F_RS16845	COG0616	signal peptide processing
HDN1F_RS16845	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HDN1F_RS16855	COG0424	maF-like protein
HDN1F_RS16865	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HDN1F_RS16870	COG0416	fatty acid biosynthetic process
HDN1F_RS16885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDN1F_RS16890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HDN1F_RS16895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HDN1F_RS16900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDN1F_RS16905	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDN1F_RS16925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HDN1F_RS16950	COG2205	protein histidine kinase activity
HDN1F_RS16950	COG5002	protein histidine kinase activity
HDN1F_RS16950	COG0784	Response regulator, receiver
HDN1F_RS16965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDN1F_RS16980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDN1F_RS16995	COG4399	Belongs to the UPF0754 family
HDN1F_RS17000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDN1F_RS17005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDN1F_RS17010	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDN1F_RS17020	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS17025	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HDN1F_RS17030	COG3100	YcgL domain-containing protein
HDN1F_RS17060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDN1F_RS17070	COG2030	dehydratase
HDN1F_RS17085	COG0318	PFAM AMP-dependent synthetase and ligase
HDN1F_RS17090	COG1643	Atp-dependent helicase
HDN1F_RS17125	COG2197	response regulator
HDN1F_RS17135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDN1F_RS17140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDN1F_RS17155	COG2204	response regulator
HDN1F_RS17160	COG2205	protein histidine kinase activity
HDN1F_RS17185	COG1230	cation diffusion facilitator family transporter
HDN1F_RS17190	COG1070	Carbohydrate kinase
HDN1F_RS17195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HDN1F_RS17200	COG0277	FAD linked oxidase domain protein
HDN1F_RS17210	COG0300	oxidoreductase activity
HDN1F_RS17215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDN1F_RS17255	COG1056	cytidyltransferase-related domain
HDN1F_RS17255	COG1051	belongs to the nudix hydrolase family
HDN1F_RS17300	COG0545	Peptidyl-prolyl cis-trans isomerase
HDN1F_RS17310	COG0739	heme binding
HDN1F_RS17315	COG1570	exodeoxyribonuclease VII activity
HDN1F_RS17330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HDN1F_RS17335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HDN1F_RS17345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HDN1F_RS17350	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS17355	COG0789	Transcriptional regulator
HDN1F_RS17365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HDN1F_RS17370	COG0039	L-malate dehydrogenase activity
HDN1F_RS17380	COG0271	Belongs to the BolA IbaG family
HDN1F_RS17395	COG0037	tRNA processing
HDN1F_RS17400	COG0700	Nucleoside recognition
HDN1F_RS17425	COG2850	peptidyl-arginine hydroxylation
HDN1F_RS17440	COG0482	sulfurtransferase activity
HDN1F_RS17450	COG0315	cyclic pyranopterin monophosphate synthase activity
HDN1F_RS17455	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HDN1F_RS17460	COG0314	molybdopterin synthase activity
HDN1F_RS17465	COG0446	pyridine nucleotide-disulphide oxidoreductase
HDN1F_RS17470	COG2197	response regulator
HDN1F_RS17475	COG0322	excinuclease ABC activity
HDN1F_RS17480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDN1F_RS17500	COG1611	Belongs to the LOG family
HDN1F_RS17515	COG5002	protein histidine kinase activity
HDN1F_RS17515	COG5001	Diguanylate cyclase
HDN1F_RS17540	COG2204	response regulator
HDN1F_RS17560	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HDN1F_RS17560	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HDN1F_RS17570	COG0166	Belongs to the GPI family
HDN1F_RS17625	COG3409	Peptidoglycan-binding domain 1 protein
HDN1F_RS17625	COG3267	Type II secretory pathway component ExeA
HDN1F_RS17640	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HDN1F_RS17650	COG2354	Protein conserved in bacteria
HDN1F_RS17665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDN1F_RS17670	COG1309	transcriptional regulator
HDN1F_RS17700	COG4974	Belongs to the 'phage' integrase family
HDN1F_RS17860	COG3344	reverse transcriptase
HDN1F_RS17895	COG2944	sequence-specific DNA binding
HDN1F_RS17915	COG2003	Belongs to the UPF0758 family
HDN1F_RS17985	COG1192	Involved in chromosome partitioning
HDN1F_RS18045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HDN1F_RS18060	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HDN1F_RS18065	COG0741	lytic transglycosylase activity
HDN1F_RS18100	COG0477	Major facilitator Superfamily
HDN1F_RS18105	COG1376	ErfK ybiS ycfS ynhG family protein
HDN1F_RS18110	COG0418	dihydroorotase activity
HDN1F_RS18115	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HDN1F_RS18120	COG4181	ATPase activity
HDN1F_RS18130	COG2918	glutathione biosynthetic process
HDN1F_RS18135	COG3130	regulation of translation
HDN1F_RS18140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HDN1F_RS18160	COG0488	(ABC) transporter
HDN1F_RS18170	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HDN1F_RS18195	COG0840	transmembrane signaling receptor activity
HDN1F_RS18205	COG2205	protein histidine kinase activity
HDN1F_RS18215	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HDN1F_RS18220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HDN1F_RS18240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HDN1F_RS18280	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HDN1F_RS18285	COG1473	amidohydrolase
HDN1F_RS18290	COG4771	TonB-dependent receptor
HDN1F_RS18325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HDN1F_RS18330	COG2022	thiamine diphosphate biosynthetic process
HDN1F_RS18340	COG0454	-acetyltransferase
HDN1F_RS18365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDN1F_RS18400	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS18415	COG0191	fructose-bisphosphate aldolase activity
HDN1F_RS18420	COG0126	phosphoglycerate kinase activity
HDN1F_RS18425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HDN1F_RS18430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDN1F_RS18435	COG0640	Transcriptional regulator
HDN1F_RS18440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDN1F_RS18445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HDN1F_RS18450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HDN1F_RS18485	COG4771	TonB-dependent receptor
HDN1F_RS18525	COG1960	acyl-CoA dehydrogenase activity
HDN1F_RS18570	COG3668	Plasmid stabilization system
HDN1F_RS18590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HDN1F_RS18600	COG2201	protein-glutamate methylesterase activity
HDN1F_RS18605	COG2198	Histidine kinase
HDN1F_RS18605	COG0784	Response regulator, receiver
HDN1F_RS18605	COG0643	Histidine kinase
HDN1F_RS18615	COG0840	transmembrane signaling receptor activity
HDN1F_RS18635	COG0189	ligase activity
HDN1F_RS18645	COG1678	Uncharacterized ACR, COG1678
HDN1F_RS18650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDN1F_RS18655	COG3128	pkhd-type hydroxylase
HDN1F_RS18665	COG4206	TonB-dependent receptor
HDN1F_RS18710	COG0535	radical SAM domain protein
HDN1F_RS18750	COG0714	Associated with various cellular activities
HDN1F_RS18760	COG2010	Cytochrome c
HDN1F_RS18770	COG0540	Belongs to the ATCase OTCase family
HDN1F_RS18785	COG5001	Diguanylate cyclase
HDN1F_RS18785	COG3300	MHYT domain
HDN1F_RS18795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HDN1F_RS18800	COG5002	protein histidine kinase activity
HDN1F_RS18800	COG0784	Response regulator, receiver
HDN1F_RS18825	COG4453	Protein conserved in bacteria
HDN1F_RS18860	COG0762	integral membrane protein
HDN1F_RS18865	COG1872	DUF167
HDN1F_RS18885	COG2161	toxin-antitoxin pair type II binding
HDN1F_RS18890	COG4115	mRNA cleavage
HDN1F_RS18900	COG3311	Transcriptional regulator
HDN1F_RS18940	COG0488	(ABC) transporter
HDN1F_RS18955	COG1943	Transposase
HDN1F_RS18985	COG4263	nitrous-oxide reductase activity
HDN1F_RS18990	COG4221	oxidoreductase activity
HDN1F_RS19015	COG1652	LysM domain
HDN1F_RS19020	COG0242	peptide deformylase activity
HDN1F_RS19025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDN1F_RS19030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDN1F_RS19040	COG3876	Protein conserved in bacteria
HDN1F_RS19080	COG1607	acyl-coa hydrolase
HDN1F_RS19085	COG0210	DNA helicase
HDN1F_RS19115	COG1376	ErfK ybiS ycfS ynhG family protein
HDN1F_RS19115	COG1388	LysM domain
HDN1F_RS19140	COG0791	NLP P60 protein
HDN1F_RS19150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HDN1F_RS19155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDN1F_RS19165	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDN1F_RS19175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDN1F_RS19185	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDN1F_RS19195	COG0356	it plays a direct role in the translocation of protons across the membrane
HDN1F_RS19205	COG1475	DNA binding
HDN1F_RS19210	COG1192	Involved in chromosome partitioning
HDN1F_RS19215	COG0357	Ribosomal RNA small subunit methyltransferase G
HDN1F_RS19220	COG0445	tRNA wobble uridine modification
HDN1F_RS19230	COG0706	membrane insertase activity
HDN1F_RS19235	COG0594	ribonuclease P activity
HDN1F_RS19240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HDN1F_RS19280	COG2205	protein histidine kinase activity
HDN1F_RS19280	COG2198	Histidine kinase
HDN1F_RS19280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HDN1F_RS19280	COG0784	Response regulator, receiver
HDN1F_RS19285	COG3079	Belongs to the UPF0149 family
HDN1F_RS19330	COG3459	Glycosyltransferase 36 associated
HDN1F_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
HDN1F_RS19415	COG0438	transferase activity, transferring glycosyl groups
HDN1F_RS19420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDN1F_RS19435	COG4942	peptidase
HDN1F_RS19440	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HDN1F_RS19450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HDN1F_RS19470	COG2272	Belongs to the type-B carboxylesterase lipase family
HDN1F_RS19485	COG5001	Diguanylate cyclase
HDN1F_RS19485	COG5002	protein histidine kinase activity
HDN1F_RS19500	COG1309	transcriptional regulator
HDN1F_RS19520	COG1404	Belongs to the peptidase S8 family
HDN1F_RS19545	COG2815	serine threonine protein kinase
HDN1F_RS19545	COG0515	serine threonine protein kinase
HDN1F_RS19605	COG2226	methyltransferase
HDN1F_RS19610	COG5002	protein histidine kinase activity
HDN1F_RS19610	COG0784	Response regulator, receiver
HDN1F_RS19610	COG2205	protein histidine kinase activity
HDN1F_RS19615	COG3706	GGDEF domain
HDN1F_RS19615	COG4251	negative regulation of phosphorylation
HDN1F_RS19615	COG5001	Diguanylate cyclase
HDN1F_RS19615	COG2203	Gaf domain
HDN1F_RS19630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HDN1F_RS19630	COG1199	ATP-dependent helicase activity
HDN1F_RS19660	COG0745	RESPONSE REGULATOR receiver
HDN1F_RS19760	COG0840	transmembrane signaling receptor activity
HDN1F_RS19765	COG0643	Histidine kinase
HDN1F_RS19765	COG2198	Histidine kinase
HDN1F_RS19775	COG0784	Response regulator, receiver
HDN1F_RS19775	COG2205	protein histidine kinase activity
HDN1F_RS19780	COG3300	MHYT domain
HDN1F_RS19780	COG5001	Diguanylate cyclase
HDN1F_RS19800	COG0719	Fe-S assembly protein
HDN1F_RS19820	COG2909	trisaccharide binding
HDN1F_RS19865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HDN1F_RS19905	COG5002	protein histidine kinase activity
HDN1F_RS19905	COG5001	Diguanylate cyclase
HDN1F_RS19910	COG2205	protein histidine kinase activity
HDN1F_RS19910	COG0784	Response regulator, receiver
HDN1F_RS19910	COG5002	protein histidine kinase activity
HDN1F_RS19930	COG2203	Gaf domain
HDN1F_RS19930	COG3706	GGDEF domain
HDN1F_RS19930	COG5001	Diguanylate cyclase
HDN1F_RS19930	COG4251	negative regulation of phosphorylation
HDN1F_RS19940	COG2264	protein methyltransferase activity
HDN1F_RS19945	COG0358	DNA primase activity
HDN1F_RS19955	COG0741	lytic transglycosylase activity
HDN1F_RS19980	COG1403	HNH endonuclease
HDN1F_RS20000	COG3115	cell septum assembly
HDN1F_RS20015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDN1F_RS20025	COG0784	Response regulator, receiver
HDN1F_RS20025	COG2205	protein histidine kinase activity
HDN1F_RS20025	COG2198	Histidine kinase
HDN1F_RS20060	COG0631	protein serine/threonine phosphatase activity
HDN1F_RS20145	COG2267	carboxylic ester hydrolase activity
HDN1F_RS20170	COG1309	transcriptional regulator
HDN1F_RS20185	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP