locus-tag	class	description
GWK26_RS00005	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GWK26_RS00010	ENOG4105CEP	NADH dehydrogenase
GWK26_RS00025	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWK26_RS00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GWK26_RS00055	ENOG4105CHM	Aminotransferase
GWK26_RS00070	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GWK26_RS00075	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GWK26_RS00090	ENOG4105CK2	sodium dicarboxylate symporter
GWK26_RS00125	ENOG4108JPW	Aminotransferase
GWK26_RS00145	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
GWK26_RS00160	ENOG4105DSE	periplasmic solute binding protein
GWK26_RS00165	ENOG4105FDK	ABC transporter
GWK26_RS00170	ENOG4105FAV	ABC, transporter
GWK26_RS00210	ENOG4105CEY	Amp-dependent synthetase and ligase
GWK26_RS00220	ENOG4105ERH	Fumarylacetoacetate hydrolase
GWK26_RS00230	ENOG4105DEN	Luciferase family
GWK26_RS00250	ENOG4107TH8	cina domain protein
GWK26_RS00300	ENOG4105DA5	(ABC) transporter
GWK26_RS00305	ENOG4107XC4	flavin reductase domain protein, FMN-binding
GWK26_RS00325	ENOG4105C26	Dehydrogenase
GWK26_RS00370	ENOG4105CXK	mandelate racemase muconate lactonizing
GWK26_RS00375	ENOG4105CPQ	Dehydrogenase
GWK26_RS00390	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
GWK26_RS00425	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
GWK26_RS00455	ENOG4105C8J	)-transporter
GWK26_RS00520	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GWK26_RS00525	ENOG4105BZU	Histidine kinase
GWK26_RS00545	ENOG4105H1G	trap transporter solute receptor taxi family
GWK26_RS00555	ENOG4105K4P	CoA-binding domain protein
GWK26_RS00565	ENOG4107WD4	Releases the N-terminal proline from various substrates (By similarity)
GWK26_RS00575	ENOG4105CK7	Sodium proline symporter
GWK26_RS00650	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWK26_RS00655	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GWK26_RS00660	ENOG4105D64	Mechanosensitive ion channel
GWK26_RS00680	ENOG4105VEQ	Cold shock protein
GWK26_RS00685	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GWK26_RS00690	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GWK26_RS00695	ENOG4107QRT	dEAD DEAH box helicase
GWK26_RS00715	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GWK26_RS00730	ENOG4105K63	Thioredoxin
GWK26_RS00735	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GWK26_RS00740	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GWK26_RS00745	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GWK26_RS00775	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GWK26_RS00800	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWK26_RS00825	ENOG4105CJW	magnesium transporter
GWK26_RS00855	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GWK26_RS00860	ENOG4107TCW	O-succinylbenzoate synthase
GWK26_RS00865	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GWK26_RS00875	ENOG4105D2S	major facilitator superfamily
GWK26_RS00885	ENOG41081QV	Universal stress protein
GWK26_RS00895	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GWK26_RS00915	ENOG4105C8N	cysteinyl-tRNA synthetase
GWK26_RS00945	ENOG4105KHC	sulfurtransferase
GWK26_RS00950	ENOG4105KHC	sulfurtransferase
GWK26_RS00955	ENOG4105C3M	thioredoxin reductase
GWK26_RS00960	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GWK26_RS00965	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GWK26_RS00970	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GWK26_RS01035	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GWK26_RS01055	ENOG4105VZ8	Transcriptional regulator
GWK26_RS01075	ENOG4105BZU	Histidine kinase
GWK26_RS01090	ENOG4105ENA	helicase
GWK26_RS01180	ENOG4105ETU	transcriptional activator (TenA
GWK26_RS01210	ENOG4105E8R	UPF0173 metal-dependent hydrolase
GWK26_RS01215	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GWK26_RS01240	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GWK26_RS01250	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GWK26_RS01285	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GWK26_RS01300	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GWK26_RS01315	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWK26_RS01335	ENOG4105DQ5	transport system permease protein
GWK26_RS01340	ENOG4105E0A	ABC, transporter
GWK26_RS01350	ENOG4108I5G	Major Facilitator superfamily
GWK26_RS01360	ENOG4108TWJ	NADH dehydrogenase subunit 5
GWK26_RS01365	ENOG4105EVH	UPF0753 protein
GWK26_RS01370	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GWK26_RS01375	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GWK26_RS01380	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GWK26_RS01385	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GWK26_RS01395	ENOG4105C7K	acetolactate synthase
GWK26_RS01400	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GWK26_RS01410	ENOG4105DFD	Na H antiporter
GWK26_RS01420	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GWK26_RS01470	ENOG4105CQB	FAD linked oxidase domain protein
GWK26_RS01480	ENOG4107QR9	Iron-sulfur cluster binding protein
GWK26_RS01495	ENOG4105DQU	oxidoreductase, subunit beta
GWK26_RS01500	ENOG4108XM1	transcriptional regulator AsnC family
GWK26_RS01515	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GWK26_RS01540	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
GWK26_RS01560	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GWK26_RS01590	ENOG4108RAV	Conserved protein
GWK26_RS01605	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GWK26_RS01620	ENOG4105E4F	Isochorismate synthase
GWK26_RS01640	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GWK26_RS01670	ENOG4105E0X	reductase
GWK26_RS01680	ENOG4107W2A	UPF0173 metal-dependent hydrolase
GWK26_RS01685	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
GWK26_RS01695	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
GWK26_RS01705	ENOG41080XP	Cbs domain
GWK26_RS01710	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GWK26_RS01740	ENOG4108EHY	type IV secretion system
GWK26_RS01755	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GWK26_RS01790	ENOG4105C1A	potassium transporter peripheral membrane
GWK26_RS01795	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GWK26_RS01800	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GWK26_RS01805	ENOG41069FQ	Metallo-beta-lactamase superfamily
GWK26_RS01810	ENOG4105EEI	dihydropteroate synthase
GWK26_RS01825	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
GWK26_RS01830	ENOG4105C3M	thioredoxin reductase
GWK26_RS01840	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GWK26_RS01855	ENOG4105KJM	monovalent cation h antiporter subunit g
GWK26_RS01870	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GWK26_RS01875	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GWK26_RS01880	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GWK26_RS01885	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GWK26_RS01900	ENOG4105E39	Enoyl-CoA hydratase
GWK26_RS01905	ENOG4105CHR	reductase
GWK26_RS01925	ENOG4108EHY	type IV secretion system
GWK26_RS01965	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GWK26_RS01970	ENOG41061GT	Aldolase
GWK26_RS02035	ENOG4105C5R	Aminotransferase
GWK26_RS02040	ENOG4105C22	threonyL-tRNA synthetase
GWK26_RS02060	ENOG4105D81	ABC transporter, permease
GWK26_RS02065	ENOG4105D38	putrescine abc transporter
GWK26_RS02085	ENOG4105DKQ	ROK family
GWK26_RS02090	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS02095	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
GWK26_RS02105	ENOG4107S4Y	M20 DapE family protein YgeY
GWK26_RS02130	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS02140	ENOG4105F38	ABC transporter, permease
GWK26_RS02145	ENOG4105D38	putrescine abc transporter
GWK26_RS02150	ENOG4108JPW	Aminotransferase
GWK26_RS02160	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GWK26_RS02165	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GWK26_RS02175	ENOG4105DGU	Histone deacetylase
GWK26_RS02190	ENOG4105ENR	peptidase, M24
GWK26_RS02205	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS02210	ENOG4105F38	ABC transporter, permease
GWK26_RS02215	ENOG4105D38	putrescine abc transporter
GWK26_RS02240	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GWK26_RS02245	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GWK26_RS02325	ENOG4107ZQV	short-chain dehydrogenase reductase
GWK26_RS02335	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GWK26_RS02410	ENOG4105D82	Glutamate dehydrogenase
GWK26_RS02415	ENOG410905X	membrane-flanked domain protein
GWK26_RS02430	ENOG4105CJ1	ABC, transporter
GWK26_RS02435	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GWK26_RS02440	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GWK26_RS02465	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GWK26_RS02530	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GWK26_RS02545	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GWK26_RS02560	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS02565	ENOG4108H51	phosphoribosylformylglycinamidine synthase
GWK26_RS02570	ENOG4105CHM	Aminotransferase
GWK26_RS02580	ENOG4105KG3	cytidine deaminase
GWK26_RS02595	ENOG4105D82	Glutamate dehydrogenase
GWK26_RS02610	ENOG4105C6T	cysteine synthase
GWK26_RS02620	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
GWK26_RS02635	ENOG4105C0B	DNA polymerase III (alpha subunit)
GWK26_RS02655	ENOG4105CH2	amidohydrolase
GWK26_RS02660	ENOG41062D9	Histidine kinase
GWK26_RS02675	ENOG4107XKF	NMT1 THI5 Like Domain Protein
GWK26_RS02680	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
GWK26_RS02685	ENOG4105D7T	ABC transporter
GWK26_RS02705	ENOG4108S4C	acetyltransferase
GWK26_RS02710	ENOG4105C12	Phosphoribosylglycinamide synthetase
GWK26_RS02715	ENOG4105C7Z	Conserved Protein
GWK26_RS02725	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GWK26_RS02730	ENOG4105CXT	aspartate transcarbamylase
GWK26_RS02735	ENOG410811Q	Ferredoxin
GWK26_RS02795	ENOG4105CIG	ABC transporter
GWK26_RS02890	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GWK26_RS02910	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GWK26_RS02920	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
GWK26_RS02950	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GWK26_RS02955	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
GWK26_RS02965	ENOG4105I7M	spermidine synthase
GWK26_RS03025	ENOG4105C28	cystathionine
GWK26_RS03035	ENOG4105D6J	arsenicaL-resistance protein
GWK26_RS03045	ENOG4105C58	cytochrome c oxidase accessory protein ccog
GWK26_RS03125	ENOG4105VF7	tolerance protein
GWK26_RS03135	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GWK26_RS03160	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GWK26_RS03165	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GWK26_RS03170	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GWK26_RS03175	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GWK26_RS03180	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GWK26_RS03190	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GWK26_RS03195	ENOG41082SA	50s ribosomal protein l29
GWK26_RS03205	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GWK26_RS03210	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GWK26_RS03225	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GWK26_RS03235	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GWK26_RS03245	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GWK26_RS03260	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GWK26_RS03270	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GWK26_RS03300	ENOG4105DCI	Phosphohydrolase
GWK26_RS03315	ENOG4105CX6	glutaminyL-tRNA synthetase
GWK26_RS03330	ENOG4105CN9	Peptidase m42 family protein
GWK26_RS03335	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GWK26_RS03365	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GWK26_RS03370	ENOG4105C12	Phosphoribosylglycinamide synthetase
GWK26_RS03395	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GWK26_RS03420	ENOG4105C9Q	fumarate hydratase class II
GWK26_RS03425	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GWK26_RS03440	ENOG4108R85	Short chain dehydrogenase
GWK26_RS03465	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GWK26_RS03490	ENOG4105K5X	acetyltransferase
GWK26_RS03510	ENOG4105CPC	Aldo Keto reductase
GWK26_RS03520	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GWK26_RS03550	ENOG4105HMI	Membrane
GWK26_RS03555	ENOG4105CN5	Metallo-Beta-Lactamase
GWK26_RS03605	ENOG4107YFT	Nadph-dependent fmn reductase
GWK26_RS03610	ENOG41080TK	Universal stress protein
GWK26_RS03615	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GWK26_RS03670	ENOG4105C32	Amino acid ABC transporter (Permease)
GWK26_RS03675	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GWK26_RS03685	ENOG4108IV0	ABC, transporter
GWK26_RS03715	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GWK26_RS03720	ENOG4105CAS	nag kinase
GWK26_RS03725	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GWK26_RS03730	ENOG4105CE9	30S ribosomal protein S2
GWK26_RS03735	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GWK26_RS03750	ENOG4108UJD	30S ribosomal protein S9
GWK26_RS03760	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GWK26_RS03775	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GWK26_RS03785	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GWK26_RS03795	ENOG4105C0H	protease
GWK26_RS03805	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
GWK26_RS03810	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GWK26_RS03820	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GWK26_RS03880	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GWK26_RS03905	ENOG4105D22	carbon starvation protein
GWK26_RS03920	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GWK26_RS03945	ENOG4105C7B	Threonine dehydratase
GWK26_RS03970	ENOG4105C8Y	Acetylornithine aminotransferase
GWK26_RS03975	ENOG4105C94	Transporter
GWK26_RS04020	ENOG4105FBW	Monooxygenase
GWK26_RS04025	ENOG4107V0Z	fmn reductase
GWK26_RS04030	ENOG4105CEV	competence damage-inducible protein
GWK26_RS04045	ENOG41083V2	Pterin carbinolamine dehydratase
GWK26_RS04050	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GWK26_RS04070	ENOG4105C5F	glutamine synthetase
GWK26_RS04095	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GWK26_RS04105	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GWK26_RS04115	ENOG4105KVY	Required for disulfide bond formation in some proteins (By similarity)
GWK26_RS04125	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GWK26_RS04135	ENOG4105C3G	gtp-binding protein
GWK26_RS04170	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GWK26_RS04190	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GWK26_RS04215	ENOG4107YZX	Universal stress protein
GWK26_RS04220	ENOG4105CEY	Amp-dependent synthetase and ligase
GWK26_RS04260	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS04270	ENOG4105BZU	Histidine kinase
GWK26_RS04290	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
GWK26_RS04305	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GWK26_RS04310	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
GWK26_RS04315	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GWK26_RS04320	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GWK26_RS04325	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GWK26_RS04330	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GWK26_RS04340	ENOG4105DK7	lysyl-tRNA synthetase
GWK26_RS04345	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GWK26_RS04355	ENOG4107S6X	Glycosyl transferase, family 2
GWK26_RS04365	ENOG4108ZAF	Molybdopterin
GWK26_RS04415	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS04420	ENOG4105E0C	molybdate abc transporter
GWK26_RS04440	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GWK26_RS04455	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GWK26_RS04470	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GWK26_RS04495	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GWK26_RS04505	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GWK26_RS04525	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
GWK26_RS04535	ENOG4105EYF	MMPL domain protein
GWK26_RS04560	ENOG4105C19	ABC transporter
GWK26_RS04565	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GWK26_RS04575	ENOG4108JPW	Aminotransferase
GWK26_RS04580	ENOG4105C26	Dehydrogenase
GWK26_RS04620	ENOG4105C0Z	ABC transporter
GWK26_RS04625	ENOG4108IV0	ABC, transporter
GWK26_RS04715	ENOG4107R5S	dna adenine
GWK26_RS04735	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GWK26_RS04755	ENOG4105C26	Dehydrogenase
GWK26_RS04850	ENOG4105ECQ	AraC Family Transcriptional Regulator
GWK26_RS04905	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GWK26_RS04920	ENOG4105CQB	FAD linked oxidase domain protein
GWK26_RS04935	ENOG4105C37	(CBS) domain
GWK26_RS04950	ENOG4108RMU	ferritin dps family protein
GWK26_RS04960	ENOG4105KST	dependent repressor
GWK26_RS04965	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
GWK26_RS04970	ENOG4107S6Z	Na H antiporter
GWK26_RS04990	ENOG4105CUB	amino acid
GWK26_RS05010	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
GWK26_RS05020	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
GWK26_RS05035	ENOG4105CEI	nitrite reductase
GWK26_RS05050	ENOG4105BZU	Histidine kinase
GWK26_RS05070	ENOG4107VT3	K03386 peroxiredoxin (alkyl hydroperoxide reductase subunit C) EC 1.11.1.15
GWK26_RS05110	ENOG4105C5R	Aminotransferase
GWK26_RS05135	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
GWK26_RS05145	ENOG4105QVC	MOSC domain-containing protein
GWK26_RS05150	ENOG4105CHM	Aminotransferase
GWK26_RS05180	ENOG41069FQ	Metallo-beta-lactamase superfamily
GWK26_RS05330	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GWK26_RS05360	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
GWK26_RS05365	ENOG4105VFE	sira family
GWK26_RS05400	ENOG4107RUY	(E1 component), alpha subunit
GWK26_RS05405	ENOG4105CPP	Dehydrogenase, E1 component
GWK26_RS05410	ENOG4105C6Z	Gluconate
GWK26_RS05415	ENOG4105CQB	FAD linked oxidase domain protein
GWK26_RS05425	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GWK26_RS05440	ENOG4105BZ1	(ABC) transporter
GWK26_RS05470	ENOG4105ENA	helicase
GWK26_RS05485	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GWK26_RS05490	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS05495	ENOG4105E2Z	phosphate ABC transporter (Permease
GWK26_RS05500	ENOG4105C8U	phosphate abc transporter
GWK26_RS05550	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
GWK26_RS05570	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GWK26_RS05595	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GWK26_RS05620	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GWK26_RS05625	ENOG4105EHU	Circadian clock protein KaiC
GWK26_RS05630	ENOG4105BZU	Histidine kinase
GWK26_RS05670	ENOG4105C2I	pirin domain protein
GWK26_RS05695	ENOG4105CXK	mandelate racemase muconate lactonizing
GWK26_RS05700	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GWK26_RS05725	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GWK26_RS05730	ENOG4108IJ9	(ABC) transporter
GWK26_RS05740	ENOG4105CXK	mandelate racemase muconate lactonizing
GWK26_RS05745	ENOG4105C5I	Dehydrogenase
GWK26_RS05760	ENOG4107S2N	Type III effector Hrp-dependent
GWK26_RS05765	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GWK26_RS05825	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GWK26_RS05830	ENOG4108ZMQ	domain protein
GWK26_RS05880	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWK26_RS05885	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWK26_RS05890	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GWK26_RS05915	ENOG4105ERH	Fumarylacetoacetate hydrolase
GWK26_RS05935	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GWK26_RS05940	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GWK26_RS05945	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GWK26_RS05950	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
GWK26_RS05970	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GWK26_RS05985	ENOG4105F38	ABC transporter, permease
GWK26_RS05990	ENOG4105D38	putrescine abc transporter
GWK26_RS05995	ENOG4108HM4	ABC transporter
GWK26_RS06000	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS06005	ENOG4105C26	Dehydrogenase
GWK26_RS06015	ENOG4105CQC	Prephenate dehydratase
GWK26_RS06020	ENOG4105C8T	Leucyl-tRNA synthetase
GWK26_RS06035	ENOG4105VEQ	Cold shock protein
GWK26_RS06055	ENOG4105DIA	mandelate racemase muconate lactonizing
GWK26_RS06080	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
GWK26_RS06090	ENOG4105BZA	Phosphoglycerate kinase
GWK26_RS06115	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GWK26_RS06120	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GWK26_RS06150	ENOG4105C32	Amino acid ABC transporter (Permease)
GWK26_RS06160	ENOG4108IV0	ABC, transporter
GWK26_RS06165	ENOG4105C0Z	ABC transporter
GWK26_RS06205	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GWK26_RS06210	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GWK26_RS06225	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GWK26_RS06250	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS06255	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GWK26_RS06290	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
GWK26_RS06305	ENOG4108VCT	Sulfite exporter TauE/SafE
GWK26_RS06320	ENOG4105C9B	Cysteine desulfurase
GWK26_RS06355	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GWK26_RS06390	ENOG4107RQ2	Cytochrome c oxidase, subunit I
GWK26_RS06395	ENOG4105NAA	Cytochrome C oxidase, subunit II
GWK26_RS06440	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GWK26_RS06445	ENOG4105CFH	Aspartokinase
GWK26_RS06460	ENOG4105ERH	Fumarylacetoacetate hydrolase
GWK26_RS06470	ENOG4105CB5	ATP-dependent DNA helicase recG
GWK26_RS06480	ENOG4105VC4	domain protein
GWK26_RS06485	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
GWK26_RS06495	ENOG4105E66	phosphoriboisomerase A
GWK26_RS06525	ENOG4105C0Z	ABC transporter
GWK26_RS06530	ENOG4108IV0	ABC, transporter
GWK26_RS06535	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GWK26_RS06595	ENOG4105C7B	Threonine dehydratase
GWK26_RS06605	ENOG4105CQB	FAD linked oxidase domain protein
GWK26_RS06610	ENOG4105BZN	citrate synthase
GWK26_RS06630	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GWK26_RS06635	ENOG4105CTD	carboxy-peptidase
GWK26_RS06660	ENOG4107QMS	site-determining protein
GWK26_RS06695	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
GWK26_RS06705	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GWK26_RS06725	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
GWK26_RS06735	ENOG4105K63	Thioredoxin
GWK26_RS06745	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GWK26_RS06750	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GWK26_RS06790	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GWK26_RS06855	ENOG4105C59	p-type ATPase
GWK26_RS06865	ENOG4108S4H	thioesterase Superfamily protein
GWK26_RS06875	ENOG4107XSR	periplasmic solute binding protein
GWK26_RS06880	ENOG4105FDK	ABC transporter
GWK26_RS06895	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GWK26_RS06905	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GWK26_RS06915	ENOG4105K64	Glycosyl transferase, family 2
GWK26_RS06925	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GWK26_RS06950	ENOG4107SRH	Nad-dependent epimerase dehydratase
GWK26_RS07000	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GWK26_RS07015	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
GWK26_RS07020	ENOG4105E1F	short-chain dehydrogenase reductase
GWK26_RS07060	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GWK26_RS07070	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GWK26_RS07095	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GWK26_RS07100	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GWK26_RS07110	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GWK26_RS07140	ENOG4105C37	(CBS) domain
GWK26_RS07155	ENOG4105CHF	Glutathione S-transferase
GWK26_RS07170	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GWK26_RS07175	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GWK26_RS07180	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GWK26_RS07185	ENOG4106M32	3-dehydroquinate synthase
GWK26_RS07195	ENOG4107S4Y	M20 DapE family protein YgeY
GWK26_RS07200	ENOG4105C32	Amino acid ABC transporter (Permease)
GWK26_RS07210	ENOG4108IV0	ABC, transporter
GWK26_RS07215	ENOG4105C0Z	ABC transporter
GWK26_RS07220	ENOG4105DV0	amidase (EC 3.5.1.4
GWK26_RS07245	ENOG4105D06	uba thif-type nad fad binding protein
GWK26_RS07270	ENOG4105C7N	Xanthine uracil vitamin C permease
GWK26_RS07275	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GWK26_RS07280	ENOG4105EAH	synthase
GWK26_RS07290	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GWK26_RS07305	ENOG4105CK7	Sodium proline symporter
GWK26_RS07335	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GWK26_RS07340	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GWK26_RS07350	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GWK26_RS07380	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GWK26_RS07395	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GWK26_RS07410	ENOG4105C5S	asparaginyl-tRNA synthetase
GWK26_RS07430	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GWK26_RS07435	ENOG4107ZYJ	bioY protein
GWK26_RS07440	ENOG4105BZ1	(ABC) transporter
GWK26_RS07450	ENOG4105DF6	Fe-S oxidoreductase
GWK26_RS07485	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GWK26_RS07530	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
GWK26_RS07565	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GWK26_RS07570	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
GWK26_RS07585	ENOG4105F2Z	3-oxoadipate enol-lactonase
GWK26_RS07590	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GWK26_RS07595	ENOG4105C1G	acyl-Coa dehydrogenase
GWK26_RS07630	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GWK26_RS07645	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GWK26_RS07655	ENOG4105C5H	ABC transporter
GWK26_RS07685	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GWK26_RS07725	ENOG4105EHU	Circadian clock protein KaiC
GWK26_RS07755	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GWK26_RS07800	ENOG4105CKK	Glycosyl transferase, family 2
GWK26_RS07810	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GWK26_RS07825	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GWK26_RS07905	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GWK26_RS07910	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GWK26_RS07925	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GWK26_RS07970	ENOG4108JU6	CBS domain protein
GWK26_RS07985	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GWK26_RS08035	ENOG4105D5P	Methylmalonyl-coA mutase
GWK26_RS08045	ENOG4108J2P	Alpha beta hydrolase fold
GWK26_RS08055	ENOG4105CHU	acetyl-coa acetyltransferase
GWK26_RS08070	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GWK26_RS08085	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GWK26_RS08095	ENOG4105F0N	pyrophosphate phospho-hydrolase
GWK26_RS08145	ENOG4105DCG	PHP domain protein
GWK26_RS08165	ENOG4105P8F	nudix hydrolase
GWK26_RS08185	ENOG4105D07	Signal peptide peptidase, SppA
GWK26_RS08195	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GWK26_RS08205	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GWK26_RS08225	ENOG4105EYH	Exonuclease
GWK26_RS08245	ENOG4105C3K	feS assembly ATPase SufC
GWK26_RS08250	ENOG4105DIW	FeS assembly protein SUFB
GWK26_RS08285	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GWK26_RS08295	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GWK26_RS08300	ENOG4105DQU	oxidoreductase, subunit beta
GWK26_RS08310	ENOG4105CV8	reductase
GWK26_RS08335	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GWK26_RS08340	ENOG4105UQX	Mate efflux family protein
GWK26_RS08360	ENOG4105E2X	shikimate dehydrogenase
GWK26_RS08365	ENOG4108I5G	Major Facilitator superfamily
GWK26_RS08385	ENOG4105DHP	deoxycytidine triphosphate deaminase
GWK26_RS08400	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GWK26_RS08410	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
GWK26_RS08430	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GWK26_RS08465	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GWK26_RS08470	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GWK26_RS08780	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GWK26_RS08800	ENOG4108ZMQ	domain protein
GWK26_RS08895	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GWK26_RS08920	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GWK26_RS08930	ENOG4105CY0	Metallo-Beta-Lactamase
GWK26_RS08945	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
GWK26_RS08960	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GWK26_RS08970	ENOG4105BZF	Glycosyl transferase (Group 1
GWK26_RS09005	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GWK26_RS09025	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GWK26_RS09085	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GWK26_RS09110	ENOG4105C6T	cysteine synthase
GWK26_RS09115	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GWK26_RS09135	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS09140	ENOG4105EHG	Permease protein
GWK26_RS09170	ENOG4108NGU	Transcriptional regulator
GWK26_RS09180	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GWK26_RS09220	ENOG4105D3Q	Sugar transferase
GWK26_RS09235	ENOG4105BZ1	(ABC) transporter
GWK26_RS09270	ENOG4105F0R	Cytidylyltransferase
GWK26_RS09275	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GWK26_RS09280	ENOG4105D2T	synthase
GWK26_RS09345	ENOG4105DNP	FAD linked oxidase domain protein
GWK26_RS09370	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GWK26_RS09375	ENOG4108IYU	L-aspartate oxidase
GWK26_RS09380	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GWK26_RS09400	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GWK26_RS09405	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GWK26_RS09410	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GWK26_RS09420	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GWK26_RS09440	ENOG4105CK7	Sodium proline symporter
GWK26_RS09455	ENOG4108JJB	ABC transporter
GWK26_RS09460	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
GWK26_RS09470	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GWK26_RS09485	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
GWK26_RS09490	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
GWK26_RS09495	ENOG4108P62	biosynthesis protein (CbiG)
GWK26_RS09500	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GWK26_RS09505	ENOG4105E4R	Precorrin-3B C17-methyltransferase
GWK26_RS09530	ENOG4105DV0	amidase (EC 3.5.1.4
GWK26_RS09545	ENOG4105D82	Glutamate dehydrogenase
GWK26_RS09615	ENOG4105D7W	serine acetyltransferase
GWK26_RS09620	ENOG4107QTF	adenylosuccinate lyase
GWK26_RS09625	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GWK26_RS09635	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GWK26_RS09640	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GWK26_RS09645	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GWK26_RS09650	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWK26_RS09655	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWK26_RS09660	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GWK26_RS09680	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWK26_RS09695	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GWK26_RS09700	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GWK26_RS09735	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GWK26_RS09740	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
GWK26_RS09750	ENOG4105C5F	glutamine synthetase
GWK26_RS09760	ENOG4105BZU	Histidine kinase
GWK26_RS09765	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
GWK26_RS09780	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GWK26_RS09790	ENOG4105CFG	Acts as a chaperone (By similarity)
GWK26_RS09795	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GWK26_RS09805	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GWK26_RS09815	ENOG4105C26	Dehydrogenase
GWK26_RS09820	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GWK26_RS09865	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GWK26_RS09880	ENOG4107XZQ	multidrug resistance protein
GWK26_RS09895	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWK26_RS09900	ENOG4105C57	major facilitator superfamily
GWK26_RS09910	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GWK26_RS09935	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
GWK26_RS09960	ENOG4105DA5	(ABC) transporter
GWK26_RS10035	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GWK26_RS10055	ENOG41080XP	Cbs domain
GWK26_RS10120	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
GWK26_RS10125	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GWK26_RS10140	ENOG4105MRR	Transcriptional regulator (By similarity)
GWK26_RS10150	ENOG4105CH2	amidohydrolase
GWK26_RS10165	ENOG4107ZT3	family UPF0126
GWK26_RS10175	ENOG4105C7B	Threonine dehydratase
GWK26_RS10180	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWK26_RS10185	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GWK26_RS10190	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GWK26_RS10200	ENOG4107HP6	Transcriptional regulator
GWK26_RS10210	ENOG4105CIG	ABC transporter
GWK26_RS10355	ENOG4107R7Y	intracellular protease Pfpi family
GWK26_RS10365	ENOG4108UNV	SUF system FeS assembly protein, NifU family
GWK26_RS10375	ENOG4107SVH	Potassium channel protein
GWK26_RS10380	ENOG4107SXA	Phosphorylase
GWK26_RS10385	ENOG4105DPN	Oligoendopeptidase f
GWK26_RS10390	ENOG4108Z7F	N-acetyltransferase
GWK26_RS10400	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GWK26_RS10415	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GWK26_RS10435	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
GWK26_RS10440	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GWK26_RS10445	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GWK26_RS10450	ENOG4108UMR	transcriptional regulator AsnC family
GWK26_RS10475	ENOG4105C8V	SAICAR synthetase
GWK26_RS10480	ENOG4105CIY	formyltetrahydrofolate deformylase
GWK26_RS10495	ENOG4107QP8	phosphohexose isomerase
GWK26_RS10525	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GWK26_RS10535	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GWK26_RS10540	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GWK26_RS10565	ENOG41061GT	Aldolase
GWK26_RS10570	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GWK26_RS10580	ENOG4105E9Z	Nad-dependent epimerase dehydratase
GWK26_RS10585	ENOG4105CTU	Proline racemase
GWK26_RS10600	ENOG4105D8K	carboxyl transferase
GWK26_RS10615	ENOG4105C45	hydrogenase expression formation protein (HypE)
GWK26_RS10620	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GWK26_RS10625	ENOG4105WKW	Pfam:DUF1458
GWK26_RS10665	ENOG4105EAC	phosphoserine phosphatase
GWK26_RS10675	ENOG4105DTQ	mandelate racemase muconate lactonizing
GWK26_RS10690	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS10715	ENOG4105HDK	L-asparaginase
GWK26_RS10735	ENOG4107258	Transcriptional regulator
GWK26_RS10740	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
GWK26_RS10750	ENOG4105RQI	acetone carboxylase gamma subunit
GWK26_RS10755	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
GWK26_RS10760	ENOG4107U7N	hydantoinase B oxoprolinase
GWK26_RS10765	ENOG4105DZS	Phenylacetate-CoA ligase
GWK26_RS10770	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GWK26_RS10775	ENOG4105CUB	amino acid
GWK26_RS10790	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GWK26_RS10795	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
GWK26_RS10800	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GWK26_RS10830	ENOG4105C32	Amino acid ABC transporter (Permease)
GWK26_RS10880	ENOG4107S1N	anthranilate phosphoribosyltransferase
GWK26_RS10885	ENOG4108UMR	transcriptional regulator AsnC family
GWK26_RS10890	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GWK26_RS10900	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GWK26_RS10910	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWK26_RS10930	ENOG4105CHU	acetyl-coa acetyltransferase
GWK26_RS10975	ENOG4108M4U	conserved membrane protein
GWK26_RS11005	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
GWK26_RS11020	ENOG4105C8J	)-transporter
GWK26_RS11025	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GWK26_RS11030	ENOG4105EWK	phytoene
GWK26_RS11070	ENOG4105CRQ	synthase (Component I)
GWK26_RS11075	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
GWK26_RS11125	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GWK26_RS11165	ENOG4105C7B	Threonine dehydratase
GWK26_RS11170	ENOG4105C94	Transporter
GWK26_RS11205	ENOG4105C94	Transporter
GWK26_RS11210	ENOG4105C10	Electron transfer flavoprotein
GWK26_RS11215	ENOG4105BZJ	Electron transfer flavoprotein
GWK26_RS11230	ENOG4105CKU	formyltetrahydrofolate synthetase
GWK26_RS11245	ENOG4105TRT	Transcriptional regulator
GWK26_RS11280	ENOG4105F5V	trimethylamine methyltransferase
GWK26_RS11295	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GWK26_RS11300	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
GWK26_RS11310	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
GWK26_RS11315	ENOG4105F38	ABC transporter, permease
GWK26_RS11320	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GWK26_RS11340	ENOG4105C8Y	Acetylornithine aminotransferase
GWK26_RS11380	ENOG4105BZU	Histidine kinase
GWK26_RS11420	ENOG4105FF2	Type I DHQase
GWK26_RS11425	ENOG4105D6E	homoserine dehydrogenase
GWK26_RS11440	ENOG4105D1Z	hydroxypyruvate reductase
GWK26_RS11445	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GWK26_RS11460	ENOG4105CGU	Enoyl-CoA hydratase
GWK26_RS11470	ENOG4107RSR	Malate quinone oxidoreductase
GWK26_RS11480	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GWK26_RS11495	ENOG4105CHU	acetyl-coa acetyltransferase
GWK26_RS11500	ENOG4105C1G	acyl-Coa dehydrogenase
GWK26_RS11505	ENOG4105E39	Enoyl-CoA hydratase
GWK26_RS11555	ENOG41060WC	Enoyl-CoA hydratase
GWK26_RS11560	ENOG4105E39	Enoyl-CoA hydratase
GWK26_RS11565	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GWK26_RS11570	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GWK26_RS11575	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GWK26_RS11605	ENOG4105C4K	Nad synthetase
GWK26_RS11625	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GWK26_RS11630	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GWK26_RS11660	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GWK26_RS11675	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GWK26_RS11690	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWK26_RS11695	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GWK26_RS11740	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GWK26_RS11760	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GWK26_RS11765	ENOG4105DWF	phosphomethylpyrimidine kinase
GWK26_RS11770	ENOG4107ZXU	DSBA oxidoreductase
GWK26_RS11795	ENOG4107JTW	chlorite dismutase
GWK26_RS11805	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GWK26_RS11970	ENOG4105BZU	Histidine kinase
GWK26_RS11980	ENOG4105C01	Dihydroxy-acid dehydratase
GWK26_RS11985	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GWK26_RS12010	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
GWK26_RS12015	ENOG4105BZU	Histidine kinase
GWK26_RS12050	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
GWK26_RS12055	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GWK26_RS12080	ENOG4105MRR	Transcriptional regulator (By similarity)
GWK26_RS12105	ENOG41080TK	Universal stress protein
GWK26_RS12130	ENOG4105D8X	mechanosensitive ion channel
GWK26_RS12135	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
GWK26_RS12145	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GWK26_RS12155	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GWK26_RS12195	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GWK26_RS12240	ENOG4105VN1	Heat shock protein
GWK26_RS12270	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
GWK26_RS12275	ENOG4107S2Z	UPF0761 membrane protein
GWK26_RS12285	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GWK26_RS12295	ENOG4105EEI	dihydropteroate synthase
GWK26_RS12320	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GWK26_RS12340	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GWK26_RS12345	ENOG4105F7P	transcriptional regulator AsnC family
GWK26_RS12355	ENOG4105VEQ	Cold shock protein
GWK26_RS12360	ENOG4105ECY	inositol monophosphatase
GWK26_RS12375	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
GWK26_RS12390	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GWK26_RS12395	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GWK26_RS12470	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GWK26_RS12480	ENOG4108IYU	L-aspartate oxidase
GWK26_RS12485	ENOG4105CQR	helicase
GWK26_RS12520	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GWK26_RS12525	ENOG4105D74	hydrolase
GWK26_RS12705	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GWK26_RS12885	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
GWK26_RS12925	ENOG4105K63	Thioredoxin
GWK26_RS12935	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GWK26_RS12960	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GWK26_RS12970	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
GWK26_RS12975	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GWK26_RS12995	ENOG4105CD3	dihydroorotase
GWK26_RS13005	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
GWK26_RS13010	ENOG4105C75	arginyL-tRNA synthetase
GWK26_RS13025	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GWK26_RS13040	ENOG4108NGU	Transcriptional regulator
GWK26_RS13095	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GWK26_RS13100	ENOG4105SHT	UspA domain-containing protein
GWK26_RS13115	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GWK26_RS13120	ENOG4105TMB	Formate nitrite transporter
GWK26_RS13160	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GWK26_RS13170	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GWK26_RS13175	ENOG4105D0M	Protease HtpX homolog
GWK26_RS13190	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GWK26_RS13200	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GWK26_RS13220	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GWK26_RS13240	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GWK26_RS13250	ENOG4105DZP	Membrane-associated zinc metalloprotease
GWK26_RS13265	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
GWK26_RS13280	ENOG4105CPC	Aldo Keto reductase
GWK26_RS13295	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GWK26_RS13340	ENOG4105IW1	AmiS UreI transporter
GWK26_RS13345	ENOG4105WMR	Protein CrcB homolog
GWK26_RS13355	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GWK26_RS13370	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GWK26_RS13375	ENOG4105DA5	(ABC) transporter
GWK26_RS13380	ENOG4105E3A	(ABC) transporter
GWK26_RS13410	ENOG4105C8M	UPF0272 protein
GWK26_RS13415	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GWK26_RS13445	ENOG4105C6K	Malic enzyme
GWK26_RS13450	ENOG4107S91	Sodium hydrogen exchanger
GWK26_RS13455	ENOG4105NCW	Trka-c domain protein
GWK26_RS13475	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GWK26_RS13500	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GWK26_RS13510	ENOG4105F9U	Dehydrogenase
GWK26_RS13515	ENOG4105C7B	Threonine dehydratase
GWK26_RS13540	ENOG4107SBK	Acetylornithine deacetylase
GWK26_RS13550	ENOG41069M3	Transcriptional regulator
GWK26_RS13560	ENOG4105C32	Amino acid ABC transporter (Permease)
GWK26_RS13570	ENOG4105C0Z	ABC transporter
GWK26_RS13575	ENOG4108IV0	ABC, transporter
GWK26_RS13580	ENOG4105D2S	major facilitator superfamily
GWK26_RS13595	ENOG4106943	Heat shock protein
GWK26_RS13600	ENOG4105F4R	Transcriptional regulator mode
GWK26_RS13625	ENOG4108JQ1	Dehydrogenase
GWK26_RS13630	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GWK26_RS13650	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GWK26_RS13660	ENOG4105D5U	fad dependent oxidoreductase
GWK26_RS13685	ENOG4105DG4	malate L-lactate dehydrogenase
GWK26_RS13695	ENOG4105DTQ	mandelate racemase muconate lactonizing
GWK26_RS13700	ENOG4108IJ9	(ABC) transporter
GWK26_RS13715	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GWK26_RS13725	ENOG4105EQX	glucarate dehydratase
GWK26_RS13735	ENOG4108JQ1	Dehydrogenase
GWK26_RS13740	ENOG4105CXK	mandelate racemase muconate lactonizing
GWK26_RS13745	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GWK26_RS13755	ENOG4105C7K	acetolactate synthase
GWK26_RS13765	ENOG4105C26	Dehydrogenase
GWK26_RS13770	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GWK26_RS13775	ENOG4105J4Q	Transcriptional regulator
GWK26_RS13780	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GWK26_RS13785	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
GWK26_RS13795	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GWK26_RS13800	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GWK26_RS13840	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GWK26_RS13845	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GWK26_RS13850	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GWK26_RS13870	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GWK26_RS13875	ENOG4105CIG	ABC transporter
GWK26_RS13915	ENOG4105DFD	Na H antiporter
GWK26_RS13950	ENOG4108J5G	6-phosphogluconate dehydrogenase
GWK26_RS13955	ENOG4105E2Z	phosphate ABC transporter (Permease
GWK26_RS13960	ENOG4105C8U	phosphate abc transporter
GWK26_RS13970	ENOG4105CUT	histidyl-tRNA synthetase
GWK26_RS13985	ENOG4105DWV	Homoserine O-trans-acetylase
GWK26_RS14060	ENOG4105C26	Dehydrogenase
GWK26_RS14065	ENOG4108IQE	Amp-dependent synthetase and ligase
GWK26_RS14075	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GWK26_RS14120	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GWK26_RS14165	ENOG4105DB7	PHP domain protein
GWK26_RS14170	ENOG4105D52	delta-aminolevulinic acid dehydratase
GWK26_RS14185	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
GWK26_RS14220	ENOG4105CGD	Nad-dependent epimerase dehydratase
GWK26_RS14240	ENOG4105CDH	Citrulline--aspartate ligase
GWK26_RS14245	ENOG4105CH7	arginosuccinase
GWK26_RS14255	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GWK26_RS14260	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GWK26_RS14265	ENOG4107U4Q	acetylglutamate kinase
GWK26_RS14270	ENOG4105C8Y	Acetylornithine aminotransferase
GWK26_RS14275	ENOG4107SBK	Acetylornithine deacetylase
GWK26_RS14280	ENOG4105DBV	ornithine carbamoyltransferase