locus-tag	class	description
AR505_RS00020	COG0183	Belongs to the thiolase family
AR505_RS00030	COG0552	protein localization to endoplasmic reticulum
AR505_RS00055	COG0084	hydrolase, TatD family'
AR505_RS00070	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AR505_RS00110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AR505_RS00120	COG1201	RNA secondary structure unwinding
AR505_RS00150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS00155	COG1120	ATPase activity
AR505_RS00165	COG0187	DNA topoisomerase II activity
AR505_RS00170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AR505_RS00190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AR505_RS00195	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AR505_RS00200	COG1201	RNA secondary structure unwinding
AR505_RS00205	COG2181	nitrate reductase activity
AR505_RS00205	COG0247	lactate metabolic process
AR505_RS00240	COG1418	mRNA catabolic process
AR505_RS00245	COG3118	belongs to the thioredoxin family
AR505_RS00250	COG0492	ferredoxin-NADP+ reductase activity
AR505_RS00270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AR505_RS00285	COG0085	RNA polymerase activity
AR505_RS00290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AR505_RS00295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AR505_RS00315	COG0284	orotidine-5'-phosphate decarboxylase activity
AR505_RS00340	COG0101	tRNA pseudouridine synthase activity
AR505_RS00345	COG0151	Belongs to the GarS family
AR505_RS00350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AR505_RS00355	COG0252	asparaginase activity
AR505_RS00365	COG2813	Specifically methylates the guanine in position
AR505_RS00370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AR505_RS00395	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AR505_RS00435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AR505_RS00440	COG2017	converts alpha-aldose to the beta-anomer
AR505_RS00490	COG0459	protein refolding
AR505_RS00495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AR505_RS00505	COG0484	heat shock protein binding
AR505_RS00525	COG4106	trans-aconitate 2-methyltransferase activity
AR505_RS00530	COG0352	thiamine-phosphate diphosphorylase activity
AR505_RS00540	COG2022	thiamine diphosphate biosynthetic process
AR505_RS00565	COG3415	Transposase
AR505_RS00565	COG2801	Transposase and inactivated derivatives
AR505_RS00570	COG2801	Transposase and inactivated derivatives
AR505_RS00570	COG3415	Transposase
AR505_RS00575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AR505_RS00580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AR505_RS00585	COG5012	cobalamin binding
AR505_RS00590	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AR505_RS00605	COG0500	methyltransferase
AR505_RS00615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AR505_RS00630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AR505_RS00670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AR505_RS00680	COG0730	response to heat
AR505_RS00695	COG0417	DNA replication proofreading
AR505_RS00700	COG0012	GTP binding
AR505_RS00705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AR505_RS00765	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AR505_RS00770	COG0006	proline dipeptidase activity
AR505_RS00775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AR505_RS00810	COG0028	Belongs to the TPP enzyme family
AR505_RS00815	COG0028	Belongs to the TPP enzyme family
AR505_RS00820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AR505_RS00835	COG0436	Aminotransferase
AR505_RS00840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AR505_RS00845	COG0019	diaminopimelate decarboxylase activity
AR505_RS00850	COG0527	aspartate kinase activity
AR505_RS00855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AR505_RS00860	COG1522	sequence-specific DNA binding
AR505_RS00865	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AR505_RS00865	COG3264	Mechanosensitive ion channel
AR505_RS00885	COG3875	lactate racemase activity
AR505_RS00890	COG2181	nitrate reductase activity
AR505_RS00890	COG0247	lactate metabolic process
AR505_RS00895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AR505_RS00935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AR505_RS00950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AR505_RS00995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AR505_RS01015	COG1304	FMN binding
AR505_RS01030	COG0477	Major facilitator Superfamily
AR505_RS01035	COG0298	carbon dioxide binding
AR505_RS01045	COG3402	PFAM membrane-flanked domain
AR505_RS01055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AR505_RS01060	COG1522	sequence-specific DNA binding
AR505_RS01065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AR505_RS01070	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AR505_RS01075	COG0154	amidase activity
AR505_RS01080	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AR505_RS01090	COG0004	ammonium transporteR
AR505_RS01095	COG0347	Belongs to the P(II) protein family
AR505_RS01115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AR505_RS01145	COG0675	Transposase, IS605 OrfB family
AR505_RS01160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AR505_RS01165	COG0088	Forms part of the polypeptide exit tunnel
AR505_RS01170	COG0089	rRNA binding
AR505_RS01175	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AR505_RS01180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AR505_RS01185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AR505_RS01190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AR505_RS01195	COG0255	Belongs to the universal ribosomal protein uL29 family
AR505_RS01210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AR505_RS01215	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AR505_RS01230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AR505_RS01235	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AR505_RS01240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AR505_RS01260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AR505_RS01270	COG0200	Binds to the 23S rRNA
AR505_RS01285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AR505_RS01325	COG0528	UMP kinase activity
AR505_RS01375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AR505_RS01385	COG0563	adenylate kinase activity
AR505_RS01390	COG0277	FAD linked oxidase domain protein
AR505_RS01425	COG0612	Peptidase, M16
AR505_RS01445	COG2048	Heterodisulfide reductase, subunit B
AR505_RS01470	COG0003	Pfam Anion-transporting ATPase
AR505_RS01485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AR505_RS01500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AR505_RS01510	COG0733	neurotransmitter:sodium symporter activity
AR505_RS01520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AR505_RS01545	COG0675	Transposase, IS605 OrfB family
AR505_RS01550	COG2848	UPF0210 protein
AR505_RS01560	COG0460	homoserine dehydrogenase
AR505_RS01570	COG0589	response to stress
AR505_RS01615	COG1120	ATPase activity
AR505_RS01620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS01630	COG2226	methyltransferase
AR505_RS01635	COG1120	ATPase activity
AR505_RS01640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS01655	COG2226	methyltransferase
AR505_RS01885	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AR505_RS01910	COG0589	response to stress
AR505_RS01945	COG0675	Transposase, IS605 OrfB family
AR505_RS01980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AR505_RS01985	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AR505_RS02000	COG1797	cobyrinic acid a,c-diamide synthase activity
AR505_RS02020	COG0475	glutathione-regulated potassium exporter activity
AR505_RS02030	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AR505_RS02050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AR505_RS02060	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AR505_RS02065	COG0124	histidyl-tRNA synthetase
AR505_RS02080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AR505_RS02115	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_RS02115	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_RS02120	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_RS02135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS02145	COG1120	ATPase activity
AR505_RS02155	COG1131	(ABC) transporter
AR505_RS02180	COG1131	(ABC) transporter
AR505_RS02200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AR505_RS02215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS02225	COG0516	GMP reductase activity
AR505_RS02225	COG0517	IMP dehydrogenase activity
AR505_RS02235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AR505_RS02235	COG0574	Belongs to the PEP-utilizing enzyme family
AR505_RS02245	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AR505_RS02250	COG1144	Oxidoreductase
AR505_RS02255	COG0674	pyruvate-flavodoxin oxidoreductase activity
AR505_RS02260	COG1013	pyruvate-flavodoxin oxidoreductase activity
AR505_RS02280	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AR505_RS02285	COG0540	Belongs to the ATCase OTCase family
AR505_RS02320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AR505_RS02335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AR505_RS02340	COG2195	Cleaves the N-terminal amino acid of tripeptides
AR505_RS02345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AR505_RS02370	COG0697	spore germination
AR505_RS02375	COG0583	DNA-binding transcription factor activity
AR505_RS02380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AR505_RS02395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AR505_RS02410	COG1234	tRNA 3'-trailer cleavage
AR505_RS02420	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
AR505_RS02440	COG0148	phosphopyruvate hydratase activity
AR505_RS02455	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AR505_RS02475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS02480	COG1120	ATPase activity
AR505_RS02490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AR505_RS02500	COG1454	alcohol dehydrogenase
AR505_RS02510	COG0140	phosphoribosyl-ATP diphosphatase activity
AR505_RS02510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AR505_RS02515	COG0107	imidazoleglycerol-phosphate synthase activity
AR505_RS02520	COG0131	Imidazoleglycerol-phosphate dehydratase
AR505_RS02530	COG1605	Chorismate mutase
AR505_RS02530	COG0077	Prephenate dehydratase
AR505_RS02545	COG3550	peptidyl-serine autophosphorylation
AR505_RS02550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AR505_RS02560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AR505_RS02565	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AR505_RS02570	COG0675	Transposase, IS605 OrfB family
AR505_RS02580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AR505_RS02585	COG0505	Belongs to the CarA family
AR505_RS02590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AR505_RS02595	COG0505	Belongs to the CarA family
AR505_RS02615	COG1830	Aldolase
AR505_RS02620	COG1465	3-dehydroquinate synthase
AR505_RS02625	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AR505_RS02630	COG0083	homoserine kinase activity
AR505_RS02635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AR505_RS02655	COG0675	Transposase, IS605 OrfB family
AR505_RS02660	COG0488	(ABC) transporter
AR505_RS02675	COG1120	ATPase activity
AR505_RS02680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS02685	COG1373	ATPase (AAA superfamily
AR505_RS02690	COG0675	Transposase, IS605 OrfB family
AR505_RS02705	COG2409	Drug exporters of the RND superfamily
AR505_RS02705	COG1033	growth of symbiont in host cell
AR505_RS02710	COG3177	Filamentation induced by cAMP protein fic
AR505_RS02730	COG0473	3-isopropylmalate dehydrogenase activity
AR505_RS02775	COG0463	Glycosyl transferase, family 2
AR505_RS02780	COG1088	dTDP-glucose 4,6-dehydratase activity
AR505_RS02785	COG0028	Belongs to the TPP enzyme family
AR505_RS02795	COG0647	UMP catabolic process
AR505_RS02805	COG0402	S-adenosylhomocysteine deaminase activity
AR505_RS02810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AR505_RS02820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AR505_RS02825	COG1216	Glycosyl transferase, family 2
AR505_RS02845	COG1088	dTDP-glucose 4,6-dehydratase activity
AR505_RS02850	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AR505_RS02865	COG3955	Domain of unknown function (DUF1919)
AR505_RS02870	COG3475	LICD family
AR505_RS02875	COG1442	glycosyl transferase family 8
AR505_RS02885	COG1215	transferase activity, transferring glycosyl groups
AR505_RS02980	COG0571	ribonuclease III activity
AR505_RS02985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AR505_RS02990	COG0675	Transposase, IS605 OrfB family
AR505_RS03005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AR505_RS03010	COG4279	zinc finger
AR505_RS03055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AR505_RS03075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AR505_RS03100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AR505_RS03140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AR505_RS03145	COG0083	homoserine kinase activity
AR505_RS03160	COG4581	dead DEAH box helicase
AR505_RS03170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AR505_RS03175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AR505_RS03180	COG1546	Belongs to the CinA family
AR505_RS03180	COG1058	Belongs to the CinA family
AR505_RS03190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AR505_RS03200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AR505_RS03210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AR505_RS03220	COG0371	Dehydrogenase
AR505_RS03225	COG0655	NAD(P)H dehydrogenase (quinone) activity
AR505_RS03240	COG2033	superoxide reductase activity
AR505_RS03245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AR505_RS03250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AR505_RS03255	COG0066	3-isopropylmalate dehydratase activity
AR505_RS03260	COG0473	3-isopropylmalate dehydrogenase activity
AR505_RS03285	COG0675	Transposase, IS605 OrfB family
AR505_RS03310	COG0352	thiamine-phosphate diphosphorylase activity
AR505_RS03315	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AR505_RS03320	COG1966	Carbon starvation protein
AR505_RS03335	COG0351	phosphomethylpyrimidine kinase
AR505_RS03395	COG1401	restriction endodeoxyribonuclease activity
AR505_RS03430	COG3415	Transposase
AR505_RS03430	COG2801	Transposase and inactivated derivatives
AR505_RS03440	COG0165	Argininosuccinate lyase
AR505_RS03445	COG0137	argininosuccinate synthase activity
AR505_RS03450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AR505_RS03455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AR505_RS03460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AR505_RS03465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AR505_RS03470	COG0675	Transposase, IS605 OrfB family
AR505_RS03480	COG0372	Belongs to the citrate synthase family
AR505_RS03555	COG0251	oxidation-reduction process
AR505_RS03560	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AR505_RS03565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AR505_RS03570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AR505_RS03590	COG1773	rubredoxin
AR505_RS03595	COG1129	ABC transporter
AR505_RS03615	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AR505_RS03620	COG0519	Catalyzes the synthesis of GMP from XMP
AR505_RS03630	COG2801	Transposase and inactivated derivatives
AR505_RS03630	COG3415	Transposase
AR505_RS03635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AR505_RS03635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AR505_RS03640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AR505_RS03640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AR505_RS03655	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AR505_RS03660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS03665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS03760	COG1733	regulation of RNA biosynthetic process
AR505_RS03775	COG0385	Bile acid
AR505_RS03780	COG2873	o-acetylhomoserine
AR505_RS03795	COG1739	Uncharacterized protein family UPF0029
AR505_RS03800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AR505_RS03820	COG0668	transmembrane transport
AR505_RS03830	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AR505_RS03870	COG1132	(ABC) transporter
AR505_RS03880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AR505_RS03900	COG0277	FAD linked oxidase domain protein
AR505_RS03905	COG2086	electron transfer activity
AR505_RS03910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AR505_RS03920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AR505_RS03940	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_RS03940	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_RS03945	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AR505_RS04025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AR505_RS04050	COG3275	phosphorelay sensor kinase activity
AR505_RS04100	COG1959	2 iron, 2 sulfur cluster binding
AR505_RS04120	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AR505_RS04125	COG0477	Major facilitator Superfamily
AR505_RS04155	COG1283	sodium-dependent phosphate transmembrane transporter activity
AR505_RS04160	COG1199	ATP-dependent helicase activity
AR505_RS04240	COG2255	four-way junction helicase activity
AR505_RS04255	COG1846	Transcriptional regulator
AR505_RS04260	COG1119	ATPase activity
AR505_RS04280	COG4651	solute:proton antiporter activity
AR505_RS04280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AR505_RS04285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AR505_RS04295	COG1122	ATPase activity
AR505_RS04310	COG0310	cobalt ion transport
AR505_RS04365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AR505_RS04540	COG1061	Type III restriction enzyme res subunit
AR505_RS04580	COG1373	ATPase (AAA superfamily
AR505_RS04620	COG1032	radical SAM domain protein
AR505_RS04625	COG0675	Transposase, IS605 OrfB family
AR505_RS04645	COG0312	modulator of DNA gyrase
AR505_RS04650	COG0312	modulator of DNA gyrase
AR505_RS04665	COG2814	Major facilitator Superfamily
AR505_RS04750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AR505_RS04760	COG3422	double-strand break repair
AR505_RS04770	COG1830	Aldolase
AR505_RS04785	COG0613	PHP domain protein
AR505_RS04810	COG0719	Fe-S assembly protein
AR505_RS04825	COG0588	phosphoglycerate mutase activity
AR505_RS04840	COG1115	amino acid carrier protein
AR505_RS04855	COG0523	cobalamin synthesis protein
AR505_RS04870	COG5012	cobalamin binding
AR505_RS04895	COG1733	regulation of RNA biosynthetic process
AR505_RS04900	COG1151	hydroxylamine reductase activity
AR505_RS04910	COG5377	YqaJ viral recombinase family
AR505_RS04935	COG1418	mRNA catabolic process
AR505_RS04955	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AR505_RS04960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AR505_RS04965	COG0163	prenyltransferase activity
AR505_RS04980	COG0495	leucyl-tRNA aminoacylation
AR505_RS04985	COG0500	methyltransferase
AR505_RS04985	COG3615	Tellurite resistance protein tehB
AR505_RS04995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AR505_RS05025	COG2226	methyltransferase
AR505_RS05030	COG0640	Transcriptional regulator
AR505_RS05040	COG1489	DNA binding
AR505_RS05090	COG1489	DNA binding
AR505_RS05095	COG2252	PERMEase
AR505_RS05125	COG0300	oxidoreductase activity
AR505_RS05130	COG0826	peptidase U32
AR505_RS05165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AR505_RS05170	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AR505_RS05185	COG3655	Transcriptional regulator
AR505_RS05210	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AR505_RS05260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AR505_RS05270	COG0167	dihydroorotate dehydrogenase activity
AR505_RS05275	COG0543	2 iron, 2 sulfur cluster binding
AR505_RS05315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AR505_RS05335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AR505_RS05335	COG1648	precorrin-2 dehydrogenase activity
AR505_RS05350	COG0113	porphobilinogen synthase activity
AR505_RS05355	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AR505_RS05405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AR505_RS05415	COG0822	iron-sulfur transferase activity
AR505_RS05440	COG5012	cobalamin binding
AR505_RS05455	COG5012	cobalamin binding
AR505_RS05480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AR505_RS05485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AR505_RS05500	COG2814	Major facilitator Superfamily
AR505_RS05535	COG1722	exodeoxyribonuclease VII activity
AR505_RS05540	COG1570	exodeoxyribonuclease VII activity
AR505_RS05575	COG1857	crispr-associated protein
AR505_RS05590	COG1518	maintenance of DNA repeat elements
AR505_RS05610	COG0530	calcium, potassium:sodium antiporter activity
AR505_RS05615	COG0488	(ABC) transporter
AR505_RS05635	COG0574	Belongs to the PEP-utilizing enzyme family
AR505_RS05635	COG3848	Pyruvate phosphate dikinase
AR505_RS05685	COG1201	RNA secondary structure unwinding
AR505_RS05700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AR505_RS05720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AR505_RS05780	COG1074	ATP-dependent DNA helicase activity
AR505_RS05800	COG1492	cobalamin metabolic process
AR505_RS05815	COG0420	3'-5' exonuclease activity
AR505_RS05820	COG4717	serine-type aminopeptidase activity
AR505_RS05825	COG0358	DNA primase activity
AR505_RS05830	COG0606	chelatase, subunit chli
AR505_RS05860	COG1980	fructose-bisphosphate aldolase activity
AR505_RS05865	COG0017	Asparaginyl-tRNA synthetase
AR505_RS05880	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AR505_RS05905	COG0512	Glutamine amidotransferase of anthranilate synthase
AR505_RS05915	COG0134	indole-3-glycerol-phosphate synthase activity
AR505_RS05930	COG0159	tryptophan synthase activity
AR505_RS05935	COG1618	nucleotide phosphatase activity, acting on free nucleotides
AR505_RS05940	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AR505_RS05945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AR505_RS05950	COG3275	phosphorelay sensor kinase activity
AR505_RS05955	COG2972	Histidine kinase
AR505_RS05955	COG0745	RESPONSE REGULATOR receiver
AR505_RS05985	COG1309	transcriptional regulator
AR505_RS05990	COG2409	Drug exporters of the RND superfamily
AR505_RS06005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AR505_RS06005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AR505_RS06010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AR505_RS06010	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AR505_RS06020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AR505_RS06055	COG0215	cysteine-tRNA ligase activity
AR505_RS06060	COG1045	serine acetyltransferase
AR505_RS06070	COG2226	methyltransferase
AR505_RS06085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS06090	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AR505_RS06095	COG0436	Aminotransferase
AR505_RS06120	COG0037	tRNA processing
AR505_RS06145	COG2255	four-way junction helicase activity
AR505_RS06155	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AR505_RS06190	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AR505_RS06200	COG0675	Transposase, IS605 OrfB family
AR505_RS06210	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AR505_RS06210	COG1918	ferrous iron import across plasma membrane
AR505_RS06215	COG1918	ferrous iron import across plasma membrane
AR505_RS06230	COG0640	Transcriptional regulator
AR505_RS06235	COG2217	Heavy metal translocating P-type atpase
AR505_RS06240	COG0443	Heat shock 70 kDa protein
AR505_RS06265	COG1187	pseudouridine synthase activity
AR505_RS06275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AR505_RS06285	COG1733	regulation of RNA biosynthetic process
AR505_RS06295	COG1971	Probably functions as a manganese efflux pump
AR505_RS06445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AR505_RS06450	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AR505_RS06490	COG0585	pseudouridine synthase activity
AR505_RS06505	COG1793	dna ligase
AR505_RS06510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AR505_RS06560	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AR505_RS06570	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AR505_RS06580	COG1120	ATPase activity
AR505_RS06585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS06600	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AR505_RS06610	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AR505_RS06620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AR505_RS06620	COG0551	DNA topoisomerase type I activity
AR505_RS06635	COG0864	Transcriptional regulator
AR505_RS06640	COG0367	asparagine synthase
AR505_RS06645	COG0285	dihydrofolate synthase activity
AR505_RS06650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AR505_RS06655	COG0375	protein maturation
AR505_RS06680	COG2076	Multidrug Resistance protein
AR505_RS06695	COG3655	Transcriptional regulator
AR505_RS06710	COG2226	methyltransferase
AR505_RS06715	COG1362	aminopeptidase activity
AR505_RS06730	COG0513	Belongs to the DEAD box helicase family
AR505_RS06740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AR505_RS06745	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AR505_RS06750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AR505_RS06775	COG5012	cobalamin binding
AR505_RS06780	COG5012	cobalamin binding
AR505_RS06800	COG5012	cobalamin binding
AR505_RS06815	COG4868	Belongs to the UPF0371 family
AR505_RS06820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AR505_RS06825	COG0513	Belongs to the DEAD box helicase family
AR505_RS06845	COG0423	glycine-tRNA ligase activity
AR505_RS06850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AR505_RS06850	COG0617	tRNA 3'-terminal CCA addition
AR505_RS06850	COG0517	IMP dehydrogenase activity
AR505_RS06855	COG0589	response to stress
AR505_RS06870	COG0492	ferredoxin-NADP+ reductase activity
AR505_RS06900	COG1592	Rubrerythrin
AR505_RS06920	COG1253	flavin adenine dinucleotide binding
AR505_RS07015	COG1185	polyribonucleotide nucleotidyltransferase activity
AR505_RS07025	COG0473	3-isopropylmalate dehydrogenase activity
AR505_RS07030	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AR505_RS07065	COG0145	ligase activity
AR505_RS07115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AR505_RS07160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AR505_RS07195	COG1078	dGTPase activity
AR505_RS07220	COG0489	protein tyrosine kinase activity
AR505_RS07230	COG0602	queuosine metabolic process
AR505_RS07235	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AR505_RS07240	COG0720	synthase
AR505_RS07270	COG2801	Transposase and inactivated derivatives
AR505_RS07270	COG3415	Transposase
AR505_RS07285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AR505_RS07310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AR505_RS07340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AR505_RS07355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AR505_RS07360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AR505_RS07405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AR505_RS07415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AR505_RS07435	COG0051	transcription antitermination factor activity, RNA binding
AR505_RS07440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AR505_RS07445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AR505_RS07450	COG0049	tRNA binding
AR505_RS07470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AR505_RS07500	COG0076	glutamate decarboxylase activity
AR505_RS07505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AR505_RS07555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AR505_RS07555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AR505_RS07565	COG3259	Nickel-dependent hydrogenase
AR505_RS07570	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AR505_RS07610	COG1185	polyribonucleotide nucleotidyltransferase activity
AR505_RS07640	COG1131	(ABC) transporter
AR505_RS07655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AR505_RS07660	COG3177	Filamentation induced by cAMP protein fic
AR505_RS07665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AR505_RS07675	COG2814	Major facilitator Superfamily
AR505_RS07685	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AR505_RS07715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS07720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS07740	COG2217	Heavy metal translocating P-type atpase
AR505_RS07750	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AR505_RS07815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS07820	COG1120	ATPase activity
AR505_RS07940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS07945	COG1120	ATPase activity
AR505_RS08090	COG0402	S-adenosylhomocysteine deaminase activity
AR505_RS08115	COG0116	Belongs to the methyltransferase superfamily
AR505_RS08115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AR505_RS08125	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AR505_RS08150	COG0482	sulfurtransferase activity
AR505_RS08155	COG1691	(AIR) carboxylase
AR505_RS08180	COG1012	belongs to the aldehyde dehydrogenase family
AR505_RS08205	COG0430	RNA-3'-phosphate cyclase activity
AR505_RS08210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AR505_RS08210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AR505_RS08220	COG0235	Class ii aldolase
AR505_RS08240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AR505_RS08255	COG1196	nuclear chromosome segregation
AR505_RS08265	COG0647	UMP catabolic process
AR505_RS08275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AR505_RS08295	COG0142	geranyltranstransferase activity
AR505_RS08320	COG1007	ATP synthesis coupled electron transport
AR505_RS08330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AR505_RS08345	COG0839	Belongs to the complex I subunit 6 family
AR505_RS08350	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AR505_RS08350	COG0493	'glutamate synthase
AR505_RS08355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AR505_RS08360	COG0649	NAD binding
AR505_RS08365	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AR505_RS08370	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AR505_RS08375	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AR505_RS08380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AR505_RS08390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AR505_RS08400	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AR505_RS08405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AR505_RS08410	COG3415	Transposase
AR505_RS08410	COG2801	Transposase and inactivated derivatives
AR505_RS08415	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AR505_RS08420	COG1850	ribulose-bisphosphate carboxylase activity
AR505_RS08425	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AR505_RS08435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AR505_RS08445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AR505_RS08450	COG3958	Transketolase
AR505_RS08455	COG3959	Transketolase, thiamine diphosphate binding domain
AR505_RS08485	COG0157	Belongs to the NadC ModD family
AR505_RS08495	COG0138	bifunctional purine biosynthesis protein purh
AR505_RS08500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AR505_RS08515	COG0301	tRNA thio-modification
AR505_RS08525	COG1199	ATP-dependent helicase activity
AR505_RS08535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AR505_RS08545	COG0436	Aminotransferase
AR505_RS08565	COG1355	regulation of microtubule-based process
AR505_RS08570	COG0052	Belongs to the universal ribosomal protein uS2 family
AR505_RS08615	COG0047	phosphoribosylformylglycinamidine synthase activity
AR505_RS08620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AR505_RS08635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AR505_RS08645	COG0659	secondary active sulfate transmembrane transporter activity
AR505_RS08665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AR505_RS08675	COG0675	Transposase, IS605 OrfB family
AR505_RS08690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AR505_RS08695	COG0517	IMP dehydrogenase activity
AR505_RS08695	COG0617	tRNA 3'-terminal CCA addition
AR505_RS08695	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AR505_RS08740	COG1120	ATPase activity
AR505_RS08745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AR505_RS08895	COG0464	growth
AR505_RS08920	COG0737	Belongs to the 5'-nucleotidase family
AR505_RS08930	COG0287	Prephenate dehydrogenase
AR505_RS08975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AR505_RS08980	COG0105	UTP biosynthetic process
AR505_RS09015	COG1215	transferase activity, transferring glycosyl groups
AR505_RS09020	COG2246	polysaccharide biosynthetic process
AR505_RS09035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AR505_RS09050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AR505_RS09080	COG3344	reverse transcriptase
AR505_RS09100	COG0281	malic enzyme
AR505_RS09145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AR505_RS09160	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AR505_RS09185	COG0081	regulation of translation
AR505_RS09210	COG0519	Catalyzes the synthesis of GMP from XMP
AR505_RS09210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AR505_RS09250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AR505_RS09285	COG1394	ATPase activity, coupled to movement of substances
AR505_RS09295	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AR505_RS09320	COG1269	ATP hydrolysis coupled proton transport
AR505_RS09345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AR505_RS09380	COG2801	Transposase and inactivated derivatives
AR505_RS09380	COG3415	Transposase
AR505_RS09385	COG1335	isochorismatase