locus-tag	class	description
MQE35_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MQE35_00010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MQE35_00020	COG0346	lactoylglutathione lyase activity
MQE35_00025	COG1012	belongs to the aldehyde dehydrogenase family
MQE35_00030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MQE35_00035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MQE35_00040	COG0440	acetolactate synthase activity
MQE35_00045	COG0028	Belongs to the TPP enzyme family
MQE35_00050	COG0129	dihydroxy-acid dehydratase activity
MQE35_00055	COG1012	belongs to the aldehyde dehydrogenase family
MQE35_00060	COG2197	response regulator
MQE35_00085	COG1984	allophanate hydrolase subunit 2
MQE35_00090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MQE35_00100	COG1914	H( )-stimulated, divalent metal cation uptake system
MQE35_00105	COG0606	chelatase, subunit chli
MQE35_00180	COG0037	tRNA processing
MQE35_00185	COG2267	carboxylic ester hydrolase activity
MQE35_00195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MQE35_00205	COG0137	argininosuccinate synthase activity
MQE35_00210	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MQE35_00215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MQE35_00220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MQE35_00230	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MQE35_00235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MQE35_00240	COG0165	Argininosuccinate lyase
MQE35_00255	COG2986	histidine ammonia-lyase
MQE35_00260	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MQE35_00265	COG1228	amidohydrolase
MQE35_00285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MQE35_00290	COG1757	Na H antiporter
MQE35_00295	COG0450	alkyl hydroperoxide reductase
MQE35_00300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_00310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MQE35_00320	COG1674	ftsk spoiiie
MQE35_00335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MQE35_00335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MQE35_00340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MQE35_00345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_00355	COG1607	acyl-coa hydrolase
MQE35_00370	COG3250	beta-galactosidase activity
MQE35_00375	COG3250	beta-galactosidase activity
MQE35_00380	COG5520	Belongs to the glycosyl hydrolase 30 family
MQE35_00385	COG0702	epimerase
MQE35_00390	COG1629	transport
MQE35_00395	COG3292	Two component regulator propeller
MQE35_00395	COG0745	RESPONSE REGULATOR receiver
MQE35_00395	COG2205	protein histidine kinase activity
MQE35_00400	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MQE35_00415	COG1629	transport
MQE35_00435	COG3250	beta-galactosidase activity
MQE35_00440	COG2755	lipolytic protein G-D-S-L family
MQE35_00450	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_00450	COG3347	Dehydrogenase
MQE35_00455	COG4952	isomerase
MQE35_00460	COG1070	Carbohydrate kinase
MQE35_00465	COG0235	Class ii aldolase
MQE35_00470	COG1304	FMN binding
MQE35_00480	COG3254	rhamnose metabolic process
MQE35_00490	COG1609	Transcriptional regulator
MQE35_00495	COG2721	sulfolactate sulfo-lyase activity
MQE35_00500	COG0246	Mannitol dehydrogenase
MQE35_00510	COG0800	Aldolase
MQE35_00520	COG1904	glucuronate isomerase
MQE35_00525	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_00530	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MQE35_00535	COG3250	beta-galactosidase activity
MQE35_00540	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MQE35_00545	COG0702	epimerase
MQE35_00550	COG4771	TonB-dependent receptor
MQE35_00565	COG2205	protein histidine kinase activity
MQE35_00565	COG0745	RESPONSE REGULATOR receiver
MQE35_00565	COG3292	Two component regulator propeller
MQE35_00570	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_00575	COG1312	Catalyzes the dehydration of D-mannonate
MQE35_00580	COG0205	6-phosphofructokinase activity
MQE35_00585	COG4771	TonB-dependent receptor
MQE35_00590	COG0702	epimerase
MQE35_00605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MQE35_00605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MQE35_00610	COG2356	endonuclease I
MQE35_00615	COG0047	phosphoribosylformylglycinamidine synthase activity
MQE35_00615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MQE35_00620	COG1022	Amp-dependent synthetase and ligase
MQE35_00625	COG1846	Transcriptional regulator
MQE35_00630	COG1250	3-hydroxyacyl-CoA dehydrogenase
MQE35_00630	COG1024	Enoyl-CoA hydratase
MQE35_00635	COG0183	Belongs to the thiolase family
MQE35_00645	COG1960	acyl-CoA dehydrogenase activity
MQE35_00660	COG3387	PFAM Glycoside hydrolase 15-related
MQE35_00665	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MQE35_00670	COG2234	aminopeptidase activity
MQE35_00700	COG0415	Belongs to the DNA photolyase family
MQE35_00705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MQE35_00725	COG0514	ATP-dependent DNA helicase (RecQ)
MQE35_00730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MQE35_00740	COG1678	Uncharacterized ACR, COG1678
MQE35_00790	COG1506	peptidase
MQE35_00790	COG0823	Involved in the tonB-independent uptake of proteins
MQE35_00795	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MQE35_00800	COG4771	TonB-dependent receptor
MQE35_00805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MQE35_00810	COG3938	Belongs to the proline racemase family
MQE35_00820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MQE35_00825	COG2207	Transcriptional regulator
MQE35_00830	COG3250	beta-galactosidase activity
MQE35_00865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MQE35_00870	COG1702	phosphate starvation-inducible protein PhoH
MQE35_00885	COG0592	DNA-directed DNA polymerase activity
MQE35_00905	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MQE35_00915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MQE35_00915	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MQE35_00970	COG4968	Prepilin-type N-terminal cleavage methylation domain
MQE35_01075	COG4771	TonB-dependent receptor
MQE35_01120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MQE35_01145	COG1012	belongs to the aldehyde dehydrogenase family
MQE35_01155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MQE35_01180	COG3360	Dodecin
MQE35_01195	COG0589	response to stress
MQE35_01205	COG5002	protein histidine kinase activity
MQE35_01215	COG1136	(ABC) transporter
MQE35_01215	COG0577	efflux transmembrane transporter activity
MQE35_01220	COG1136	(ABC) transporter
MQE35_01235	COG1127	ABC transporter
MQE35_01240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MQE35_01250	COG1611	Belongs to the LOG family
MQE35_01265	COG1595	DNA-templated transcription, initiation
MQE35_01275	COG4771	TonB-dependent receptor
MQE35_01280	COG0702	epimerase
MQE35_01285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_01290	COG0612	Peptidase, M16
MQE35_01300	COG2249	NAD(P)H dehydrogenase (quinone) activity
MQE35_01315	COG1629	transport
MQE35_01335	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_01345	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_01350	COG2207	Transcriptional regulator
MQE35_01360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MQE35_01360	COG2207	Transcriptional regulator
MQE35_01400	COG0702	epimerase
MQE35_01405	COG1629	transport
MQE35_01430	COG0183	Belongs to the thiolase family
MQE35_01435	COG0791	NLP P60 protein
MQE35_01445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MQE35_01450	COG0542	response to heat
MQE35_01460	COG0189	ligase activity
MQE35_01460	COG4067	protein conserved in archaea
MQE35_01470	COG0482	sulfurtransferase activity
MQE35_01475	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MQE35_01480	COG0706	membrane insertase activity
MQE35_01485	COG0504	CTP synthase activity
MQE35_01490	COG3530	Putative quorum-sensing-regulated virulence factor
MQE35_01500	COG0519	Catalyzes the synthesis of GMP from XMP
MQE35_01500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MQE35_01505	COG0076	glutamate decarboxylase activity
MQE35_01515	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MQE35_01525	COG0516	GMP reductase activity
MQE35_01525	COG0517	IMP dehydrogenase activity
MQE35_01535	COG3487	Iron-regulated protein
MQE35_01565	COG1730	sister chromatid segregation
MQE35_01575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MQE35_01580	COG0167	dihydroorotate dehydrogenase activity
MQE35_01585	COG2195	Cleaves the N-terminal amino acid of tripeptides
MQE35_01605	COG2096	Adenosyltransferase
MQE35_01615	COG0653	protein targeting
MQE35_01630	COG1595	DNA-templated transcription, initiation
MQE35_01640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MQE35_01655	COG1595	DNA-templated transcription, initiation
MQE35_01670	COG3952	Lipid A Biosynthesis
MQE35_01670	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MQE35_01685	COG0671	phosphoesterase, PA-phosphatase related
MQE35_01695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MQE35_01715	COG4974	Belongs to the 'phage' integrase family
MQE35_01735	COG1473	amidohydrolase
MQE35_01760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MQE35_01790	COG0714	Associated with various cellular activities
MQE35_01800	COG0783	Belongs to the Dps family
MQE35_01850	COG4948	Mandelate Racemase Muconate Lactonizing
MQE35_01870	COG4771	TonB-dependent receptor
MQE35_01880	COG0492	ferredoxin-NADP+ reductase activity
MQE35_01890	COG0303	'Molybdopterin
MQE35_01915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MQE35_01915	COG1648	precorrin-2 dehydrogenase activity
MQE35_01960	COG0243	molybdopterin cofactor binding
MQE35_01965	COG1116	anion transmembrane transporter activity
MQE35_01970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MQE35_01970	COG1116	anion transmembrane transporter activity
MQE35_01975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MQE35_01980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MQE35_01980	COG1116	anion transmembrane transporter activity
MQE35_02005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MQE35_02010	COG3279	Response regulator of the LytR AlgR family
MQE35_02030	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
MQE35_02045	COG1446	asparaginase
MQE35_02065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE35_02075	COG3250	beta-galactosidase activity
MQE35_02080	COG3408	Glycogen debranching enzyme
MQE35_02090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MQE35_02110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_02125	COG1629	transport
MQE35_02125	COG4206	TonB-dependent receptor
MQE35_02145	COG0671	phosphoesterase, PA-phosphatase related
MQE35_02150	COG2194	sulfuric ester hydrolase activity
MQE35_02220	COG3275	phosphorelay sensor kinase activity
MQE35_02245	COG0577	efflux transmembrane transporter activity
MQE35_02250	COG1136	(ABC) transporter
MQE35_02260	COG2755	lipolytic protein G-D-S-L family
MQE35_02260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MQE35_02265	COG1595	DNA-templated transcription, initiation
MQE35_02290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MQE35_02295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MQE35_02300	COG2205	protein histidine kinase activity
MQE35_02300	COG3437	response regulator, receiver
MQE35_02300	COG3850	Histidine kinase
MQE35_02300	COG4999	Histidine kinase
MQE35_02305	COG1663	tetraacyldisaccharide 4'-kinase activity
MQE35_02310	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MQE35_02330	COG0300	oxidoreductase activity
MQE35_02335	COG2003	Belongs to the UPF0758 family
MQE35_02370	COG1917	Cupin 2, conserved barrel domain protein
MQE35_02370	COG4977	sequence-specific DNA binding
MQE35_02390	COG0105	UTP biosynthetic process
MQE35_02400	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MQE35_02410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MQE35_02415	COG1522	sequence-specific DNA binding
MQE35_02425	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MQE35_02430	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MQE35_02445	COG3186	Phenylalanine-4-hydroxylase
MQE35_02455	COG2195	Cleaves the N-terminal amino acid of tripeptides
MQE35_02465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MQE35_02470	COG1228	amidohydrolase
MQE35_02480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MQE35_02485	COG0501	Belongs to the peptidase M48B family
MQE35_02490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MQE35_02500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MQE35_02510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MQE35_02530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MQE35_02550	COG1418	mRNA catabolic process
MQE35_02590	COG1104	cysteine desulfurase activity
MQE35_02630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MQE35_02635	COG1472	Belongs to the glycosyl hydrolase 3 family
MQE35_02645	COG2181	nitrate reductase activity
MQE35_02645	COG0247	lactate metabolic process
MQE35_02655	COG2181	nitrate reductase activity
MQE35_02655	COG0247	lactate metabolic process
MQE35_02660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MQE35_02665	COG0860	N-Acetylmuramoyl-L-alanine amidase
MQE35_02670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MQE35_02675	COG0251	oxidation-reduction process
MQE35_02715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MQE35_02720	COG1120	ATPase activity
MQE35_02725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MQE35_02730	COG1322	Protein conserved in bacteria
MQE35_02755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MQE35_02760	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MQE35_02780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MQE35_02800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MQE35_02825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MQE35_02850	COG2270	Major facilitator Superfamily
MQE35_02865	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MQE35_02880	COG2361	Protein of unknown function DUF86
MQE35_02890	COG0534	Mate efflux family protein
MQE35_02895	COG3956	TIGRFAM MazG family protein
MQE35_02930	COG0242	peptide deformylase activity
MQE35_02935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MQE35_02940	COG2171	N-acyltransferase activity
MQE35_02965	COG0438	transferase activity, transferring glycosyl groups
MQE35_02975	COG0009	L-threonylcarbamoyladenylate synthase
MQE35_02985	COG1612	heme a metabolic process
MQE35_03025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MQE35_03030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MQE35_03035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MQE35_03040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MQE35_03045	COG0561	phosphatase activity
MQE35_03060	COG4206	TonB-dependent receptor
MQE35_03060	COG1629	transport
MQE35_03075	COG0305	Participates in initiation and elongation during chromosome replication
MQE35_03080	COG0825	malonyl-CoA metabolic process
MQE35_03095	COG0343	queuine tRNA-ribosyltransferase activity
MQE35_03110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MQE35_03135	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MQE35_03140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MQE35_03165	COG1233	COG1233 Phytoene dehydrogenase and related
MQE35_03180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_03200	COG0714	Associated with various cellular activities
MQE35_03205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MQE35_03225	COG1733	regulation of RNA biosynthetic process
MQE35_03235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MQE35_03250	COG0450	alkyl hydroperoxide reductase
MQE35_03260	COG3264	Mechanosensitive ion channel
MQE35_03260	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MQE35_03265	COG1668	transmembrane transport
MQE35_03270	COG4152	abc transporter atp-binding protein
MQE35_03275	COG0484	heat shock protein binding
MQE35_03280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MQE35_03295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MQE35_03295	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MQE35_03300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MQE35_03320	COG3279	Response regulator of the LytR AlgR family
MQE35_03325	COG2205	protein histidine kinase activity
MQE35_03330	COG0653	protein targeting
MQE35_03350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MQE35_03360	COG1741	Belongs to the pirin family
MQE35_03365	COG3844	kynureninase activity
MQE35_03380	COG0671	phosphoesterase, PA-phosphatase related
MQE35_03385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MQE35_03390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MQE35_03450	COG3609	addiction module antidote protein, CC2985 family
MQE35_03465	COG3340	Belongs to the peptidase S51 family
MQE35_03475	COG1477	protein flavinylation
MQE35_03490	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MQE35_03495	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MQE35_03500	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MQE35_03505	COG1805	sodium ion transport
MQE35_03510	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MQE35_03570	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MQE35_03575	COG0357	Ribosomal RNA small subunit methyltransferase G
MQE35_03580	COG3239	Fatty acid desaturase
MQE35_03640	COG1609	Transcriptional regulator
MQE35_03645	COG3525	Glycosyl hydrolase, family 20, catalytic domain
MQE35_03650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MQE35_03660	COG1609	Transcriptional regulator
MQE35_03670	COG0363	glucosamine-6-phosphate deaminase activity
MQE35_03685	COG0702	epimerase
MQE35_03690	COG4771	TonB-dependent receptor
MQE35_03695	COG1904	glucuronate isomerase
MQE35_03700	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_03705	COG1609	Transcriptional regulator
MQE35_03710	COG1312	Catalyzes the dehydration of D-mannonate
MQE35_03720	COG0363	glucosamine-6-phosphate deaminase activity
MQE35_03750	COG1752	Esterase of the alpha-beta hydrolase superfamily
MQE35_03830	COG3451	type IV secretory pathway VirB4
MQE35_03905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MQE35_03910	COG1785	Belongs to the alkaline phosphatase family
MQE35_03915	COG1629	transport
MQE35_03920	COG0561	phosphatase activity
MQE35_03935	COG1629	transport
MQE35_03940	COG5434	Belongs to the glycosyl hydrolase 28 family
MQE35_03945	COG3119	arylsulfatase activity
MQE35_03965	COG0702	epimerase
MQE35_03970	COG4771	TonB-dependent receptor
MQE35_03980	COG1501	Belongs to the glycosyl hydrolase 31 family
MQE35_03985	COG1472	Belongs to the glycosyl hydrolase 3 family
MQE35_04025	COG4771	TonB-dependent receptor
MQE35_04050	COG3250	beta-galactosidase activity
MQE35_04065	COG4206	TonB-dependent receptor
MQE35_04065	COG1629	transport
MQE35_04070	COG2207	Transcriptional regulator
MQE35_04070	COG4753	response regulator
MQE35_04120	COG1295	ribonuclease BN
MQE35_04145	COG1610	YqeY-like protein
MQE35_04150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MQE35_04165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MQE35_04170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MQE35_04175	COG0772	Belongs to the SEDS family
MQE35_04180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MQE35_04185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MQE35_04190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MQE35_04205	COG0275	rRNA processing
MQE35_04210	COG2001	Belongs to the MraZ family
MQE35_04220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MQE35_04235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MQE35_04245	COG0358	DNA primase activity
MQE35_04270	COG4585	Histidine kinase
MQE35_04305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MQE35_04325	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_04340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MQE35_04345	COG0295	cytidine deaminase activity
MQE35_04355	COG0515	serine threonine protein kinase
MQE35_04355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MQE35_04360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MQE35_04370	COG4585	Histidine kinase
MQE35_04410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MQE35_04425	COG1629	transport
MQE35_04425	COG4206	TonB-dependent receptor
MQE35_04440	COG0471	metal ion transport
MQE35_04455	COG0321	lipoyl(octanoyl) transferase activity
MQE35_04470	COG0401	homolog of Blt101
MQE35_04475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MQE35_04495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MQE35_04500	COG0791	NLP P60 protein
MQE35_04500	COG1388	LysM domain
MQE35_04505	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MQE35_04540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MQE35_04575	COG1160	GTP binding
MQE35_04600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MQE35_04605	COG1115	amino acid carrier protein
MQE35_04765	COG0202	RNA polymerase activity
MQE35_04830	COG1476	TRANSCRIPTIONal
MQE35_04850	COG1917	Cupin 2, conserved barrel domain protein
MQE35_04850	COG4977	sequence-specific DNA binding
MQE35_04855	COG4221	oxidoreductase activity
MQE35_04860	COG0667	Aldo Keto reductase
MQE35_04875	COG0671	phosphoesterase, PA-phosphatase related
MQE35_04910	COG1785	Belongs to the alkaline phosphatase family
MQE35_04925	COG1136	(ABC) transporter
MQE35_04955	COG3867	Arabinogalactan endo-beta-1,4-galactanase
MQE35_04965	COG0702	epimerase
MQE35_04970	COG4206	TonB-dependent receptor
MQE35_04970	COG1629	transport
MQE35_04975	COG0745	RESPONSE REGULATOR receiver
MQE35_04975	COG3292	Two component regulator propeller
MQE35_04975	COG2205	protein histidine kinase activity
MQE35_04985	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MQE35_04990	COG1085	galactose-1-phosphate uridylyltransferase
MQE35_05025	COG4221	oxidoreductase activity
MQE35_05030	COG4977	sequence-specific DNA binding
MQE35_05030	COG1917	Cupin 2, conserved barrel domain protein
MQE35_05035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MQE35_05060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MQE35_05070	COG0346	lactoylglutathione lyase activity
MQE35_05095	COG1280	lysine exporter protein (LysE YggA)
MQE35_05185	COG0574	Belongs to the PEP-utilizing enzyme family
MQE35_05185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MQE35_05190	COG0488	(ABC) transporter
MQE35_05200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MQE35_05220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MQE35_05240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MQE35_05245	COG3829	transcription factor binding
MQE35_05265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MQE35_05270	COG0459	protein refolding
MQE35_05290	COG2217	Heavy metal translocating P-type atpase
MQE35_05295	COG2205	protein histidine kinase activity
MQE35_05295	COG3292	Two component regulator propeller
MQE35_05295	COG0745	RESPONSE REGULATOR receiver
MQE35_05305	COG0138	bifunctional purine biosynthesis protein purh
MQE35_05310	COG1077	Cell shape determining protein MreB Mrl
MQE35_05325	COG0768	penicillin binding
MQE35_05330	COG0772	Belongs to the SEDS family
MQE35_05335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MQE35_05345	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MQE35_05355	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MQE35_05360	COG0791	NLP P60 protein
MQE35_05365	COG0658	competence protein
MQE35_05365	COG2333	competence protein COMEC
MQE35_05375	COG3104	oligopeptide transport
MQE35_05380	COG0823	Involved in the tonB-independent uptake of proteins
MQE35_05380	COG1506	peptidase
MQE35_05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MQE35_05405	COG1253	flavin adenine dinucleotide binding
MQE35_05430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MQE35_05445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MQE35_05450	COG1472	Belongs to the glycosyl hydrolase 3 family
MQE35_05455	COG1082	Xylose isomerase domain protein TIM barrel
MQE35_05460	COG3250	beta-galactosidase activity
MQE35_05470	COG0561	phosphatase activity
MQE35_05475	COG4771	TonB-dependent receptor
MQE35_05480	COG2115	Belongs to the xylose isomerase family
MQE35_05505	COG2814	Major facilitator Superfamily
MQE35_05510	COG1621	beta-fructofuranosidase activity
MQE35_05545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MQE35_05550	COG2226	methyltransferase
MQE35_05580	COG0740	serine-type endopeptidase activity
MQE35_05595	COG1215	transferase activity, transferring glycosyl groups
MQE35_05605	COG0577	efflux transmembrane transporter activity
MQE35_05605	COG1136	(ABC) transporter
MQE35_05610	COG1136	(ABC) transporter
MQE35_05615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE35_05635	COG3275	phosphorelay sensor kinase activity
MQE35_05670	COG1187	pseudouridine synthase activity
MQE35_05695	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MQE35_05705	COG2081	HI0933 family
MQE35_05710	COG0584	glycerophosphoryl diester phosphodiesterase
MQE35_05715	COG0366	Alpha amylase catalytic
MQE35_05720	COG1082	Xylose isomerase domain protein TIM barrel
MQE35_05725	COG1501	Belongs to the glycosyl hydrolase 31 family
MQE35_05730	COG0366	Alpha amylase catalytic
MQE35_05735	COG1554	hydrolase, family 65, central catalytic
MQE35_05740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MQE35_05755	COG4206	TonB-dependent receptor
MQE35_05755	COG1629	transport
MQE35_05780	COG1609	Transcriptional regulator
MQE35_05785	COG4771	TonB-dependent receptor
MQE35_05800	COG4206	TonB-dependent receptor
MQE35_05800	COG1629	transport
MQE35_05835	COG4124	Belongs to the glycosyl hydrolase 26 family
MQE35_05840	COG2942	2-epimerase
MQE35_05850	COG1331	Highly conserved protein containing a thioredoxin domain
MQE35_05880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MQE35_05900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MQE35_05905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MQE35_05940	COG1490	D-aminoacyl-tRNA deacylase activity
MQE35_05945	COG1162	GTPase activity
MQE35_05955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MQE35_05960	COG0287	Prephenate dehydrogenase
MQE35_05965	COG0436	Aminotransferase
MQE35_05970	COG1605	Chorismate mutase
MQE35_05970	COG0077	Prephenate dehydratase
MQE35_05975	COG0156	8-amino-7-oxononanoate synthase activity
MQE35_05980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE35_05985	COG1522	sequence-specific DNA binding
MQE35_05990	COG1131	(ABC) transporter
MQE35_06005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MQE35_06015	COG0646	methionine synthase
MQE35_06015	COG1410	methionine synthase
MQE35_06020	COG0492	ferredoxin-NADP+ reductase activity
MQE35_06025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MQE35_06035	COG0460	homoserine dehydrogenase
MQE35_06035	COG0527	aspartate kinase activity
MQE35_06040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MQE35_06045	COG1428	Deoxynucleoside kinase
MQE35_06050	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MQE35_06055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MQE35_06065	COG0022	dehydrogenase e1 component
MQE35_06065	COG0508	dehydrogenase complex catalyzes the overall conversion of
MQE35_06070	COG2086	electron transfer activity
MQE35_06075	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MQE35_06085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MQE35_06105	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MQE35_06110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MQE35_06125	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MQE35_06135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MQE35_06155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MQE35_06165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MQE35_06175	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MQE35_06185	COG0596	Alpha beta hydrolase
MQE35_06195	COG1950	PFAM Membrane protein of
MQE35_06200	COG0544	peptidyl-prolyl cis-trans isomerase activity
MQE35_06210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MQE35_06230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MQE35_06240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MQE35_06245	COG1278	Cold shock
MQE35_06275	COG1064	alcohol dehydrogenase
MQE35_06300	COG2217	Heavy metal translocating P-type atpase
MQE35_06315	COG1473	amidohydrolase
MQE35_06335	COG3278	Belongs to the heme-copper respiratory oxidase family
MQE35_06350	COG0348	domain, Protein
MQE35_06365	COG0427	acetyl-CoA hydrolase
MQE35_06370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MQE35_06390	COG0616	signal peptide processing
MQE35_06395	COG1428	Deoxynucleoside kinase
MQE35_06405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MQE35_06420	COG2226	methyltransferase
MQE35_06425	COG4977	sequence-specific DNA binding
MQE35_06500	COG0346	lactoylglutathione lyase activity
MQE35_06510	COG2972	Histidine kinase
MQE35_06515	COG3279	Response regulator of the LytR AlgR family
MQE35_06555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MQE35_06565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MQE35_06575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MQE35_06580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MQE35_06585	COG3279	Response regulator of the LytR AlgR family
MQE35_06590	COG3275	phosphorelay sensor kinase activity
MQE35_06625	COG1331	Highly conserved protein containing a thioredoxin domain
MQE35_06630	COG0668	transmembrane transport
MQE35_06635	COG1214	PFAM Peptidase M22, glycoprotease
MQE35_06645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE35_06650	COG1136	(ABC) transporter
MQE35_06650	COG0577	efflux transmembrane transporter activity
MQE35_06655	COG0577	efflux transmembrane transporter activity
MQE35_06655	COG1136	(ABC) transporter
MQE35_06660	COG1136	(ABC) transporter
MQE35_06670	COG2322	membrane
MQE35_06675	COG1999	signal sequence binding
MQE35_06695	COG1845	cytochrome c oxidase, subunit III
MQE35_06700	COG0109	protoheme IX farnesyltransferase activity
MQE35_06720	COG0509	glycine decarboxylation via glycine cleavage system
MQE35_06730	COG0632	four-way junction helicase activity
MQE35_06745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MQE35_06750	COG2255	four-way junction helicase activity
MQE35_06760	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MQE35_06820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MQE35_06825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MQE35_06845	COG3743	rRNA binding
MQE35_06845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MQE35_06850	COG0437	4 iron, 4 sulfur cluster binding
MQE35_06865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MQE35_06870	COG2251	uridine kinase activity
MQE35_06870	COG0195	Participates in both transcription termination and antitermination
MQE35_06875	COG0779	Required for maturation of 30S ribosomal subunits
MQE35_06880	COG0589	response to stress
MQE35_06900	COG0726	polysaccharide deacetylase
MQE35_06905	COG3118	belongs to the thioredoxin family
MQE35_06910	COG1408	metallophosphoesterase
MQE35_06920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MQE35_06920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MQE35_06925	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MQE35_06930	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MQE35_06935	COG0052	Belongs to the universal ribosomal protein uS2 family
MQE35_06940	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MQE35_06945	COG0528	UMP kinase activity
MQE35_06950	COG0233	cytoplasmic translational termination
MQE35_06965	COG0017	Asparaginyl-tRNA synthetase
MQE35_07000	COG0811	peptide transport
MQE35_07010	COG0252	asparaginase activity
MQE35_07020	COG0084	hydrolase, TatD family'
MQE35_07035	COG2197	response regulator
MQE35_07040	COG0508	dehydrogenase complex catalyzes the overall conversion of
MQE35_07060	COG1228	amidohydrolase
MQE35_07065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MQE35_07075	COG1519	Transferase
MQE35_07075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MQE35_07090	COG1733	regulation of RNA biosynthetic process
MQE35_07105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MQE35_07120	COG0745	RESPONSE REGULATOR receiver
MQE35_07165	COG3279	Response regulator of the LytR AlgR family
MQE35_07175	COG4251	negative regulation of phosphorylation
MQE35_07185	COG4251	negative regulation of phosphorylation
MQE35_07195	COG0784	Response regulator, receiver
MQE35_07200	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MQE35_07210	COG2315	Protein conserved in bacteria
MQE35_07235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MQE35_07240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MQE35_07265	COG2115	Belongs to the xylose isomerase family
MQE35_07270	COG1070	Carbohydrate kinase
MQE35_07275	COG1609	Transcriptional regulator
MQE35_07285	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MQE35_07305	COG1904	glucuronate isomerase
MQE35_07310	COG1472	Belongs to the glycosyl hydrolase 3 family
MQE35_07315	COG3661	Belongs to the glycosyl hydrolase 67 family
MQE35_07320	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_07325	COG1312	Catalyzes the dehydration of D-mannonate
MQE35_07335	COG3118	belongs to the thioredoxin family
MQE35_07350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MQE35_07395	COG2378	regulation of single-species biofilm formation
MQE35_07450	COG4585	Histidine kinase
MQE35_07460	COG0423	glycine-tRNA ligase activity
MQE35_07470	COG1040	competence protein
MQE35_07505	COG4771	TonB-dependent receptor
MQE35_07510	COG0166	Belongs to the GPI family
MQE35_07530	COG1752	Esterase of the alpha-beta hydrolase superfamily
MQE35_07535	COG0322	excinuclease ABC activity
MQE35_07540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MQE35_07545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MQE35_07590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MQE35_07595	COG4206	TonB-dependent receptor
MQE35_07600	COG1381	Involved in DNA repair and RecF pathway recombination
MQE35_07605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MQE35_07700	COG4251	negative regulation of phosphorylation
MQE35_07710	COG0784	Response regulator, receiver
MQE35_07720	COG0644	oxidoreductase
MQE35_07740	COG2211	Major facilitator Superfamily
MQE35_07745	COG0673	inositol 2-dehydrogenase activity
MQE35_07785	COG1561	YicC-like family, N-terminal region
MQE35_07790	COG0194	GDP metabolic process
MQE35_07795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MQE35_07800	COG1652	LysM domain
MQE35_07810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MQE35_07815	COG3153	acetyltransferase
MQE35_07815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MQE35_07820	COG2897	thiosulfate sulfurtransferase activity
MQE35_07830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MQE35_07835	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MQE35_07845	COG4953	penicillin-binding protein 1C
MQE35_07860	COG2373	Large extracellular alpha-helical protein
MQE35_07865	COG1446	asparaginase
MQE35_07890	COG4260	virion core protein, lumpy skin disease virus
MQE35_07900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MQE35_07910	COG4221	oxidoreductase activity
MQE35_07915	COG0714	Associated with various cellular activities
MQE35_07930	COG2304	oxidoreductase activity
MQE35_07935	COG2304	oxidoreductase activity
MQE35_07960	COG0659	secondary active sulfate transmembrane transporter activity
MQE35_07970	COG0659	secondary active sulfate transmembrane transporter activity
MQE35_07975	COG0288	reversible hydration of carbon dioxide
MQE35_08005	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MQE35_08015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MQE35_08030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE35_08040	COG1538	Outer membrane efflux protein
MQE35_08060	COG2954	triphosphatase activity
MQE35_08070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MQE35_08075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MQE35_08085	COG0469	pyruvate kinase activity
MQE35_08095	COG0571	ribonuclease III activity
MQE35_08100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MQE35_08105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MQE35_08115	COG0328	RNA-DNA hybrid ribonuclease activity
MQE35_08120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MQE35_08130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MQE35_08155	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_08175	COG1858	cytochrome C peroxidase
MQE35_08205	COG0720	synthase
MQE35_08225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MQE35_08225	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MQE35_08240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MQE35_08250	COG1435	thymidine kinase activity
MQE35_08255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MQE35_08260	COG1970	mechanosensitive ion channel activity
MQE35_08265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MQE35_08275	COG1505	serine-type exopeptidase activity
MQE35_08285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MQE35_08310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MQE35_08330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MQE35_08340	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MQE35_08345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MQE35_08350	COG0511	ligase activity, forming carbon-carbon bonds
MQE35_08355	COG0439	Biotin carboxylase
MQE35_08385	COG0667	Aldo Keto reductase
MQE35_08395	COG0667	Aldo Keto reductase
MQE35_08405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_08425	COG0673	inositol 2-dehydrogenase activity
MQE35_08435	COG3250	beta-galactosidase activity
MQE35_08455	COG1752	Esterase of the alpha-beta hydrolase superfamily
MQE35_08460	COG2153	protein acetylation
MQE35_08470	COG0698	ribose 5-phosphate isomerase
MQE35_08480	COG0557	exoribonuclease II activity
MQE35_08505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MQE35_08510	COG0445	tRNA wobble uridine modification
MQE35_08515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MQE35_08525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MQE35_08535	COG2706	6-phosphogluconolactonase activity
MQE35_08560	COG2197	response regulator
MQE35_08565	COG1342	Belongs to the UPF0251 family
MQE35_08575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MQE35_08575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MQE35_08585	COG0824	Thioesterase
MQE35_08595	COG0446	pyridine nucleotide-disulphide oxidoreductase
MQE35_08615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MQE35_08620	COG0346	lactoylglutathione lyase activity
MQE35_08645	COG1715	Restriction endonuclease
MQE35_08650	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MQE35_08695	COG2197	response regulator
MQE35_08700	COG4585	Histidine kinase
MQE35_08710	COG1629	transport
MQE35_08710	COG4206	TonB-dependent receptor
MQE35_08765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MQE35_08770	COG4591	ABC-type transport system involved in lipoprotein release permease component
MQE35_08775	COG0667	Aldo Keto reductase
MQE35_08780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MQE35_08785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MQE35_08795	COG0481	GTPase activity
MQE35_08800	COG0297	glycogen (starch) synthase activity
MQE35_08805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MQE35_08810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MQE35_08825	COG0025	NhaP-type Na H and K H
MQE35_08850	COG0517	IMP dehydrogenase activity
MQE35_08855	COG0594	ribonuclease P activity
MQE35_08860	COG0793	Belongs to the peptidase S41A family
MQE35_08865	COG0470	DNA polymerase III
MQE35_08870	COG0126	phosphoglycerate kinase activity
MQE35_08875	COG1388	LysM domain
MQE35_08875	COG3942	CHAP domain
MQE35_08885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MQE35_08890	COG4942	peptidase
MQE35_08910	COG0529	Catalyzes the synthesis of activated sulfate
MQE35_08915	COG0175	sulfate reduction
MQE35_08960	COG1086	Polysaccharide biosynthesis protein
MQE35_08965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MQE35_08970	COG1083	cytidylyl-transferase
MQE35_08980	COG2089	acid synthase
MQE35_09035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MQE35_09045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE35_09065	COG0151	Belongs to the GarS family
MQE35_09080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MQE35_09090	COG0859	PFAM glycosyl transferase family 9
MQE35_09100	COG1418	mRNA catabolic process
MQE35_09110	COG0583	DNA-binding transcription factor activity
MQE35_09115	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MQE35_09135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MQE35_09145	COG1053	succinate dehydrogenase
MQE35_09155	COG0006	proline dipeptidase activity
MQE35_09170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MQE35_09180	COG0719	Fe-S assembly protein
MQE35_09190	COG0396	ATPase activity
MQE35_09195	COG0719	Fe-S assembly protein
MQE35_09205	COG1012	belongs to the aldehyde dehydrogenase family
MQE35_09220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MQE35_09235	COG2166	iron-sulfur cluster assembly
MQE35_09240	COG2151	metal-sulfur cluster biosynthetic enzyme
MQE35_09255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MQE35_09275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MQE35_09280	COG1253	flavin adenine dinucleotide binding
MQE35_09290	COG0113	porphobilinogen synthase activity
MQE35_09295	COG0408	coproporphyrinogen oxidase activity
MQE35_09305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MQE35_09315	COG0181	hydroxymethylbilane synthase activity
MQE35_09320	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MQE35_09335	COG4172	Belongs to the ABC transporter superfamily
MQE35_09355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MQE35_09360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MQE35_09370	COG1774	PSP1 C-terminal conserved region
MQE35_09380	COG0826	peptidase U32
MQE35_09390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MQE35_09400	COG1595	DNA-templated transcription, initiation
MQE35_09420	COG1024	Enoyl-CoA hydratase
MQE35_09430	COG3275	phosphorelay sensor kinase activity
MQE35_09435	COG3279	Response regulator of the LytR AlgR family
MQE35_09450	COG3250	beta-galactosidase activity
MQE35_09465	COG0750	zinc metalloprotease
MQE35_09470	COG1999	signal sequence binding
MQE35_09500	COG4771	TonB-dependent receptor
MQE35_09520	COG1309	transcriptional regulator
MQE35_09550	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MQE35_09565	COG1278	Cold shock
MQE35_09580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MQE35_09590	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MQE35_09595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MQE35_09595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MQE35_09610	COG2095	MarC family integral membrane protein
MQE35_09625	COG0793	Belongs to the peptidase S41A family
MQE35_09650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MQE35_09690	COG0356	it plays a direct role in the translocation of protons across the membrane
MQE35_09695	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MQE35_09700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MQE35_09705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MQE35_09710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MQE35_09715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MQE35_09730	COG0756	dUTP diphosphatase activity
MQE35_09735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MQE35_09755	COG1607	acyl-coa hydrolase
MQE35_09760	COG1472	Belongs to the glycosyl hydrolase 3 family
MQE35_09775	COG0758	DNA mediated transformation
MQE35_09780	COG5000	phosphorelay sensor kinase activity
MQE35_09785	COG1981	membrane
MQE35_09795	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MQE35_09805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MQE35_09805	COG2169	Transcriptional regulator
MQE35_09810	COG3292	Two component regulator propeller
MQE35_09810	COG2205	protein histidine kinase activity
MQE35_09810	COG0745	RESPONSE REGULATOR receiver
MQE35_09820	COG1629	transport
MQE35_09840	COG0529	Catalyzes the synthesis of activated sulfate
MQE35_09870	COG0702	epimerase
MQE35_09875	COG4771	TonB-dependent receptor
MQE35_09880	COG2205	protein histidine kinase activity
MQE35_09880	COG0745	RESPONSE REGULATOR receiver
MQE35_09880	COG3292	Two component regulator propeller
MQE35_09910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MQE35_09925	COG0363	glucosamine-6-phosphate deaminase activity
MQE35_09930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MQE35_09935	COG1858	cytochrome C peroxidase
MQE35_09980	COG1136	(ABC) transporter
MQE35_09980	COG0577	efflux transmembrane transporter activity
MQE35_09985	COG0577	efflux transmembrane transporter activity
MQE35_09990	COG0577	efflux transmembrane transporter activity
MQE35_09995	COG0577	efflux transmembrane transporter activity
MQE35_10000	COG0577	efflux transmembrane transporter activity
MQE35_10005	COG0577	efflux transmembrane transporter activity
MQE35_10010	COG1136	(ABC) transporter
MQE35_10025	COG3852	Histidine kinase
MQE35_10050	COG0783	Belongs to the Dps family
MQE35_10070	COG3590	peptidase
MQE35_10090	COG0517	IMP dehydrogenase activity
MQE35_10090	COG0617	tRNA 3'-terminal CCA addition
MQE35_10090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MQE35_10155	COG0629	single-stranded DNA binding
MQE35_10165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE35_10180	COG0671	phosphoesterase, PA-phosphatase related
MQE35_10185	COG3119	arylsulfatase activity
MQE35_10195	COG1629	transport
MQE35_10215	COG3119	arylsulfatase activity
MQE35_10225	COG1501	Belongs to the glycosyl hydrolase 31 family
MQE35_10235	COG3123	guanosine phosphorylase activity
MQE35_10245	COG0673	inositol 2-dehydrogenase activity
MQE35_10260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MQE35_10260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MQE35_10275	COG1619	proteins homologs of microcin C7 resistance protein MccF
MQE35_10280	COG0792	nuclease activity
MQE35_10290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MQE35_10300	COG0228	four-way junction DNA binding
MQE35_10305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MQE35_10310	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MQE35_10315	COG1960	acyl-CoA dehydrogenase activity
MQE35_10330	COG1528	Iron-storage protein
MQE35_10375	COG0251	oxidation-reduction process
MQE35_10385	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MQE35_10420	COG2318	DinB family
MQE35_10425	COG0384	phenazine biosynthesis protein PhzF
MQE35_10465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MQE35_10470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MQE35_10475	COG0193	aminoacyl-tRNA hydrolase activity
MQE35_10480	COG4771	TonB-dependent receptor
MQE35_10505	COG0784	Response regulator, receiver
MQE35_10505	COG2205	protein histidine kinase activity
MQE35_10530	COG0527	aspartate kinase activity
MQE35_10540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MQE35_10565	COG0346	lactoylglutathione lyase activity
MQE35_10610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MQE35_10615	COG2239	Acts as a magnesium transporter
MQE35_10620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MQE35_10635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MQE35_10645	COG0196	riboflavin kinase activity
MQE35_10660	COG0708	Exodeoxyribonuclease III
MQE35_10665	COG1360	Flagellar Motor Protein
MQE35_10670	COG0667	Aldo Keto reductase
MQE35_10675	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MQE35_10695	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MQE35_10700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MQE35_10705	COG0297	glycogen (starch) synthase activity
MQE35_10715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MQE35_10735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MQE35_10755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MQE35_10760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MQE35_10785	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MQE35_10795	COG2137	regulation of response to DNA damage stimulus
MQE35_10800	COG1530	ribonuclease E activity
MQE35_10805	COG0776	regulation of translation
MQE35_10815	COG0629	single-stranded DNA binding
MQE35_10850	COG2217	Heavy metal translocating P-type atpase
MQE35_10865	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MQE35_10870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MQE35_10890	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MQE35_10895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MQE35_10935	COG0784	Response regulator, receiver
MQE35_10935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MQE35_10935	COG2198	Histidine kinase
MQE35_10935	COG2205	protein histidine kinase activity
MQE35_10955	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MQE35_10970	COG3852	Histidine kinase
MQE35_10980	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MQE35_10985	COG0519	Catalyzes the synthesis of GMP from XMP
MQE35_10995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MQE35_11000	COG1968	undecaprenyl-diphosphatase activity
MQE35_11010	COG2177	Part of the ABC transporter FtsEX involved in
MQE35_11025	COG0495	leucyl-tRNA aminoacylation
MQE35_11040	COG4095	Psort location CytoplasmicMembrane, score
MQE35_11155	COG1522	sequence-specific DNA binding
MQE35_11160	COG2363	Small membrane protein
MQE35_11175	COG0463	Glycosyl transferase, family 2
MQE35_11180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MQE35_11195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MQE35_11200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE35_11215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MQE35_11260	COG2824	Alkylphosphonate utilization operon protein PhnA
MQE35_11270	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MQE35_11285	COG2361	Protein of unknown function DUF86
MQE35_11305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MQE35_11310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MQE35_11310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MQE35_11360	COG0489	protein tyrosine kinase activity
MQE35_11380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MQE35_11390	COG5002	protein histidine kinase activity
MQE35_11395	COG0745	RESPONSE REGULATOR receiver
MQE35_11430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MQE35_11445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MQE35_11450	COG0563	adenylate kinase activity
MQE35_11455	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MQE35_11465	COG3275	phosphorelay sensor kinase activity
MQE35_11470	COG3279	Response regulator of the LytR AlgR family
MQE35_11485	COG2003	Belongs to the UPF0758 family
MQE35_11495	COG2885	chlorophyll binding
MQE35_11515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MQE35_11525	COG2003	Belongs to the UPF0758 family
MQE35_11535	COG1011	Hydrolase
MQE35_11555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MQE35_11565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MQE35_11580	COG4771	TonB-dependent receptor
MQE35_11595	COG1629	transport
MQE35_11605	COG1629	transport
MQE35_11610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MQE35_11615	COG0049	tRNA binding
MQE35_11620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MQE35_11625	COG0051	transcription antitermination factor activity, RNA binding
MQE35_11630	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MQE35_11635	COG0088	Forms part of the polypeptide exit tunnel
MQE35_11640	COG0089	rRNA binding
MQE35_11645	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MQE35_11650	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MQE35_11655	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MQE35_11660	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MQE35_11665	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MQE35_11670	COG0255	Belongs to the universal ribosomal protein uL29 family
MQE35_11675	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MQE35_11680	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MQE35_11685	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MQE35_11690	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MQE35_11695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MQE35_11700	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MQE35_11705	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MQE35_11710	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MQE35_11715	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MQE35_11720	COG1841	ribosomal large subunit assembly
MQE35_11725	COG0200	Binds to the 23S rRNA
MQE35_11730	COG0201	protein transport
MQE35_11735	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MQE35_11740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MQE35_11745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MQE35_11750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MQE35_11755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MQE35_11760	COG0202	RNA polymerase activity
MQE35_11765	COG0203	ribosomal protein L17
MQE35_11775	COG0505	Belongs to the CarA family
MQE35_11780	COG0148	phosphopyruvate hydratase activity
MQE35_11785	COG0297	glycogen (starch) synthase activity
MQE35_11800	COG1012	belongs to the aldehyde dehydrogenase family
MQE35_11820	COG0602	queuosine metabolic process
MQE35_11825	COG0433	COG0433 Predicted ATPase
MQE35_11835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MQE35_11835	COG0662	Cupin 2, conserved barrel domain protein
MQE35_11850	COG0823	Involved in the tonB-independent uptake of proteins
MQE35_11870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MQE35_11875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MQE35_11905	COG4206	TonB-dependent receptor
MQE35_11920	COG0018	arginyl-trna synthetase
MQE35_11950	COG2723	6-phospho-beta-galactosidase activity
MQE35_11980	COG0577	efflux transmembrane transporter activity
MQE35_11985	COG3876	Protein conserved in bacteria
MQE35_12000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MQE35_12035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MQE35_12035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE35_12040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE35_12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MQE35_12050	COG0450	alkyl hydroperoxide reductase
MQE35_12060	COG1271	oxidase subunit
MQE35_12065	COG1294	oxidase, subunit
MQE35_12105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MQE35_12110	COG3069	C4-dicarboxylate transmembrane transporter activity
MQE35_12125	COG2442	InterPro IPR007367
MQE35_12155	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MQE35_12170	COG4771	TonB-dependent receptor
MQE35_12175	COG0702	epimerase
MQE35_12185	COG3507	Belongs to the glycosyl hydrolase 43 family
MQE35_12190	COG3507	Belongs to the glycosyl hydrolase 43 family
MQE35_12195	COG3250	beta-galactosidase activity
MQE35_12220	COG2160	L-arabinose isomerase activity
MQE35_12280	COG4452	Inner membrane protein CreD
MQE35_12330	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MQE35_12335	COG1217	gtp-binding protein TYPA
MQE35_12345	COG2884	Cell division ATP-binding protein ftsE
MQE35_12360	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MQE35_12370	COG0367	asparagine synthase
MQE35_12375	COG0187	DNA topoisomerase II activity
MQE35_12395	COG0039	L-malate dehydrogenase activity
MQE35_12400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MQE35_12415	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MQE35_12420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MQE35_12425	COG4115	mRNA cleavage
MQE35_12435	COG0215	cysteine-tRNA ligase activity
MQE35_12440	COG0302	gtp cyclohydrolase
MQE35_12455	COG0442	prolyl-tRNA aminoacylation
MQE35_12470	COG0268	Binds directly to 16S ribosomal RNA
MQE35_12475	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MQE35_12480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MQE35_12485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MQE35_12495	COG0823	Involved in the tonB-independent uptake of proteins
MQE35_12495	COG1506	peptidase
MQE35_12495	COG4946	Tricorn protease homolog
MQE35_12515	COG0101	tRNA pseudouridine synthase activity
MQE35_12520	COG1132	(ABC) transporter
MQE35_12530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MQE35_12555	COG0149	triose-phosphate isomerase activity
MQE35_12560	COG2264	protein methyltransferase activity
MQE35_12780	COG0358	DNA primase activity
MQE35_12800	COG2909	trisaccharide binding
MQE35_12835	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MQE35_12840	COG3292	Two component regulator propeller
MQE35_12840	COG2205	protein histidine kinase activity
MQE35_12840	COG0745	RESPONSE REGULATOR receiver
MQE35_12845	COG1629	transport
MQE35_12885	COG2207	Transcriptional regulator
MQE35_12885	COG1917	Cupin 2, conserved barrel domain protein
MQE35_12895	COG4771	TonB-dependent receptor
MQE35_12900	COG0702	epimerase
MQE35_12920	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MQE35_12920	COG4447	cellulose binding
MQE35_12935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE35_12940	COG1131	(ABC) transporter
MQE35_12945	COG1131	(ABC) transporter
MQE35_12950	COG0842	Transport permease protein
MQE35_12955	COG0842	Transport permease protein
MQE35_12965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MQE35_13045	COG0739	heme binding
MQE35_13055	COG3451	type IV secretory pathway VirB4
MQE35_13105	COG1595	DNA-templated transcription, initiation
MQE35_13120	COG4771	TonB-dependent receptor
MQE35_13130	COG1629	transport
MQE35_13140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_13145	COG0612	Peptidase, M16
MQE35_13150	COG0612	Peptidase, M16
MQE35_13165	COG0667	Aldo Keto reductase
MQE35_13255	COG0285	dihydrofolate synthase activity
MQE35_13265	COG0848	biopolymer transport protein
MQE35_13270	COG0811	peptide transport
MQE35_13285	COG1960	acyl-CoA dehydrogenase activity
MQE35_13290	COG0067	glutamate synthase
MQE35_13290	COG0069	glutamate synthase activity
MQE35_13290	COG0070	glutamate synthase
MQE35_13305	COG0463	Glycosyl transferase, family 2
MQE35_13320	COG0702	epimerase
MQE35_13325	COG4771	TonB-dependent receptor
MQE35_13330	COG1917	Cupin 2, conserved barrel domain protein
MQE35_13330	COG2207	Transcriptional regulator
MQE35_13370	COG0668	transmembrane transport
MQE35_13385	COG2205	protein histidine kinase activity
MQE35_13385	COG3292	Two component regulator propeller
MQE35_13385	COG0745	RESPONSE REGULATOR receiver
MQE35_13395	COG1917	Cupin 2, conserved barrel domain protein
MQE35_13395	COG2207	Transcriptional regulator
MQE35_13420	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_13425	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_13435	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_13455	COG0693	protein deglycase activity
MQE35_13460	COG2169	Transcriptional regulator
MQE35_13470	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
MQE35_13475	COG4771	TonB-dependent receptor
MQE35_13480	COG0561	phosphatase activity
MQE35_13490	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MQE35_13495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MQE35_13525	COG0174	glutamine synthetase
MQE35_13540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MQE35_13545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_13565	COG3698	Phosphodiester glycosidase
MQE35_13580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MQE35_13585	COG0471	metal ion transport
MQE35_13590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MQE35_13600	COG0284	orotidine-5'-phosphate decarboxylase activity
MQE35_13615	COG0788	formyltetrahydrofolate deformylase activity
MQE35_13630	COG2814	Major facilitator Superfamily
MQE35_13645	COG0004	ammonium transporteR
MQE35_13655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MQE35_13660	COG1185	polyribonucleotide nucleotidyltransferase activity
MQE35_13665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MQE35_13670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MQE35_13675	COG0191	fructose-bisphosphate aldolase activity
MQE35_13685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MQE35_13695	COG2226	methyltransferase
MQE35_13700	COG0569	domain protein
MQE35_13705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MQE35_13745	COG4771	TonB-dependent receptor
MQE35_13765	COG3279	Response regulator of the LytR AlgR family
MQE35_13770	COG3275	phosphorelay sensor kinase activity
MQE35_13775	COG4771	TonB-dependent receptor
MQE35_13785	COG0363	glucosamine-6-phosphate deaminase activity
MQE35_13795	COG3525	Glycosyl hydrolase, family 20, catalytic domain
MQE35_13820	COG0517	IMP dehydrogenase activity
MQE35_13825	COG0492	ferredoxin-NADP+ reductase activity
MQE35_13830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MQE35_13835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MQE35_13840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MQE35_13845	COG1181	Belongs to the D-alanine--D-alanine ligase family
MQE35_13865	COG0564	pseudouridine synthase activity
MQE35_13875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MQE35_13920	COG3022	response to hydroperoxide
MQE35_13935	COG3275	phosphorelay sensor kinase activity
MQE35_13985	COG0159	tryptophan synthase activity
MQE35_13990	COG0133	tryptophan synthase activity
MQE35_13995	COG0135	phosphoribosylanthranilate isomerase activity
MQE35_14000	COG0134	indole-3-glycerol-phosphate synthase activity
MQE35_14005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MQE35_14010	COG0512	Glutamine amidotransferase of anthranilate synthase
MQE35_14010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MQE35_14015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MQE35_14025	COG0778	Nitroreductase
MQE35_14030	COG1846	Transcriptional regulator
MQE35_14035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_14045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MQE35_14060	COG4771	TonB-dependent receptor
MQE35_14065	COG2207	Transcriptional regulator
MQE35_14065	COG0662	Cupin 2, conserved barrel domain protein
MQE35_14080	COG0569	domain protein
MQE35_14085	COG1115	amino acid carrier protein
MQE35_14095	COG1960	acyl-CoA dehydrogenase activity
MQE35_14105	COG0366	Alpha amylase catalytic
MQE35_14110	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MQE35_14120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MQE35_14160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MQE35_14165	COG0081	regulation of translation
MQE35_14170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MQE35_14175	COG0222	ribosome binding
MQE35_14180	COG0085	RNA polymerase activity
MQE35_14185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MQE35_14195	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MQE35_14210	COG5183	chlorophyll binding
MQE35_14210	COG2133	pyrroloquinoline quinone binding
MQE35_14230	COG2885	chlorophyll binding
MQE35_14235	COG2204	response regulator
MQE35_14255	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MQE35_14265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MQE35_14270	COG1482	cell wall glycoprotein biosynthetic process
MQE35_14290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MQE35_14300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MQE35_14310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MQE35_14390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MQE35_14400	COG1475	DNA binding
MQE35_14405	COG1192	Involved in chromosome partitioning
MQE35_14410	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_14415	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MQE35_14415	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MQE35_14420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MQE35_14420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MQE35_14440	COG2133	pyrroloquinoline quinone binding
MQE35_14480	COG1917	Cupin 2, conserved barrel domain protein
MQE35_14480	COG2207	Transcriptional regulator
MQE35_14500	COG2258	MOSC domain
MQE35_14505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MQE35_14525	COG2326	polyphosphate kinase activity
MQE35_14575	COG0300	oxidoreductase activity
MQE35_14580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MQE35_14590	COG2201	protein-glutamate methylesterase activity
MQE35_14595	COG4251	negative regulation of phosphorylation
MQE35_14610	COG0488	(ABC) transporter
MQE35_14655	COG0326	Molecular chaperone. Has ATPase activity
MQE35_14660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MQE35_14665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MQE35_14670	COG0280	phosphate acetyltransferase
MQE35_14670	COG0857	belongs to the CobB CobQ family
MQE35_14685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MQE35_14690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MQE35_14695	COG0508	dehydrogenase complex catalyzes the overall conversion of
MQE35_14700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MQE35_14715	COG1058	Belongs to the CinA family
MQE35_14715	COG1546	Belongs to the CinA family
MQE35_14720	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MQE35_14725	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MQE35_14735	COG0552	protein localization to endoplasmic reticulum
MQE35_14740	COG0154	amidase activity
MQE35_14750	COG1132	(ABC) transporter
MQE35_14755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MQE35_14780	COG3537	Alpha-1,2-mannosidase
MQE35_14785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MQE35_14805	COG0525	valine-tRNA ligase activity
MQE35_14815	COG0688	phosphatidylethanolamine metabolic process
MQE35_14820	COG4589	Belongs to the CDS family
MQE35_14830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MQE35_14835	COG0799	negative regulation of ribosome biogenesis
MQE35_14840	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MQE35_14840	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MQE35_14850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MQE35_14860	COG0659	secondary active sulfate transmembrane transporter activity
MQE35_14880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MQE35_14885	COG2066	Belongs to the glutaminase family
MQE35_14895	COG2154	pterin-4-alpha-carbinolamine dehydratase
MQE35_14900	COG0217	transcriptional regulatory protein
MQE35_14910	COG1595	DNA-templated transcription, initiation
MQE35_14920	COG1454	alcohol dehydrogenase
MQE35_14930	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MQE35_14940	COG0647	UMP catabolic process
MQE35_14950	COG0174	glutamine synthetase
MQE35_14955	COG1162	GTPase activity
MQE35_14960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MQE35_15010	COG4771	TonB-dependent receptor
MQE35_15015	COG0702	epimerase
MQE35_15035	COG0045	succinate-CoA ligase (ADP-forming) activity
MQE35_15045	COG0175	sulfate reduction
MQE35_15060	COG1472	Belongs to the glycosyl hydrolase 3 family
MQE35_15070	COG0071	Belongs to the small heat shock protein (HSP20) family
MQE35_15085	COG0640	Transcriptional regulator
MQE35_15090	COG0556	nucleotide-excision repair
MQE35_15105	COG1131	(ABC) transporter
MQE35_15115	COG0438	transferase activity, transferring glycosyl groups
MQE35_15190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MQE35_15210	COG1216	Glycosyl transferase, family 2
MQE35_15225	COG0438	transferase activity, transferring glycosyl groups
MQE35_15230	COG1216	Glycosyl transferase, family 2
MQE35_15245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MQE35_15250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MQE35_15255	COG1086	Polysaccharide biosynthesis protein
MQE35_15265	COG3206	protein involved in exopolysaccharide biosynthesis
MQE35_15265	COG0489	protein tyrosine kinase activity
MQE35_15285	COG0071	Belongs to the small heat shock protein (HSP20) family
MQE35_15335	COG0298	carbon dioxide binding
MQE35_15340	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MQE35_15350	COG3259	Nickel-dependent hydrogenase
MQE35_15355	COG3383	formate dehydrogenase (NAD+) activity
MQE35_15360	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MQE35_15365	COG0375	protein maturation
MQE35_15370	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MQE35_15375	COG0409	Hydrogenase expression formation protein
MQE35_15395	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MQE35_15400	COG2224	Isocitrate lyase
MQE35_15420	COG2176	DNA-directed DNA polymerase activity
MQE35_15435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MQE35_15445	COG5002	protein histidine kinase activity
MQE35_15450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MQE35_15490	COG4221	oxidoreductase activity
MQE35_15505	COG0793	Belongs to the peptidase S41A family
MQE35_15505	COG4946	Tricorn protease homolog
MQE35_15515	COG4771	TonB-dependent receptor
MQE35_15535	COG4771	TonB-dependent receptor
MQE35_15540	COG0702	epimerase
MQE35_15555	COG1472	Belongs to the glycosyl hydrolase 3 family
MQE35_15565	COG3119	arylsulfatase activity
MQE35_15580	COG3250	beta-galactosidase activity
MQE35_15610	COG0628	permease
MQE35_15625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MQE35_15635	COG0205	6-phosphofructokinase activity
MQE35_15665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MQE35_15685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MQE35_15695	COG2226	methyltransferase
MQE35_15705	COG0352	thiamine-phosphate diphosphorylase activity
MQE35_15715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MQE35_15725	COG1295	ribonuclease BN
MQE35_15735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MQE35_15740	COG3279	Response regulator of the LytR AlgR family
MQE35_15745	COG0360	Binds together with S18 to 16S ribosomal RNA
MQE35_15750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MQE35_15755	COG0359	binds to the 23S rRNA
MQE35_15770	COG0124	histidyl-tRNA synthetase
MQE35_15805	COG1363	Peptidase, m42
MQE35_15840	COG1272	protein, Hemolysin III
MQE35_15855	COG0116	Belongs to the methyltransferase superfamily
MQE35_15870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MQE35_15880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MQE35_15885	COG0488	(ABC) transporter
MQE35_15905	COG1137	ATPase activity
MQE35_15915	COG0805	protein transport
MQE35_15920	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MQE35_15920	COG0517	IMP dehydrogenase activity
MQE35_15925	COG0514	ATP-dependent DNA helicase (RecQ)
MQE35_15935	COG3345	alpha-galactosidase
MQE35_15945	COG1629	transport
MQE35_15945	COG4206	TonB-dependent receptor
MQE35_15960	COG3275	phosphorelay sensor kinase activity
MQE35_15975	COG3279	Response regulator of the LytR AlgR family
MQE35_15985	COG0540	Belongs to the ATCase OTCase family
MQE35_15995	COG1234	tRNA 3'-trailer cleavage
MQE35_16000	COG0259	pyridoxamine-phosphate oxidase activity
MQE35_16010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MQE35_16015	COG0248	Ppx GppA phosphatase
MQE35_16025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MQE35_16040	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MQE35_16040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MQE35_16045	COG0460	homoserine dehydrogenase
MQE35_16045	COG0527	aspartate kinase activity
MQE35_16050	COG0083	homoserine kinase activity
MQE35_16055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MQE35_16095	COG1595	DNA-templated transcription, initiation
MQE35_16100	COG0673	inositol 2-dehydrogenase activity
MQE35_16120	COG0424	maF-like protein
MQE35_16135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MQE35_16135	COG1333	cytochrome c biogenesis protein
MQE35_16145	COG0534	Mate efflux family protein
MQE35_16150	COG0386	Belongs to the glutathione peroxidase family
MQE35_16155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MQE35_16165	COG2234	aminopeptidase activity
MQE35_16200	COG0584	glycerophosphoryl diester phosphodiesterase
MQE35_16215	COG0702	epimerase
MQE35_16220	COG4206	TonB-dependent receptor
MQE35_16220	COG1629	transport
MQE35_16255	COG1858	cytochrome C peroxidase
MQE35_16260	COG0738	Major facilitator superfamily
MQE35_16270	COG3537	Alpha-1,2-mannosidase
MQE35_16280	COG1940	carbohydrate kinase activity
MQE35_16290	COG3537	Alpha-1,2-mannosidase
MQE35_16295	COG3507	Belongs to the glycosyl hydrolase 43 family
MQE35_16310	COG0335	large ribosomal subunit rRNA binding
MQE35_16315	COG0336	Belongs to the RNA methyltransferase TrmD family
MQE35_16325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MQE35_16330	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MQE35_16335	COG0456	acetyltransferase
MQE35_16340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MQE35_16350	COG0473	3-isopropylmalate dehydrogenase activity
MQE35_16355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MQE35_16370	COG0564	pseudouridine synthase activity
MQE35_16375	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MQE35_16385	COG0443	Heat shock 70 kDa protein
MQE35_16400	COG2050	protein possibly involved in aromatic compounds catabolism
MQE35_16405	COG1169	isochorismate synthase
MQE35_16410	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MQE35_16425	COG2996	Protein conserved in bacteria
MQE35_16445	COG1575	Belongs to the MenA family. Type 1 subfamily
MQE35_16450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MQE35_16455	COG4948	Mandelate Racemase Muconate Lactonizing
MQE35_16475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MQE35_16485	COG0488	(ABC) transporter
MQE35_16490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MQE35_16500	COG0308	aminopeptidase N
MQE35_16525	COG0069	glutamate synthase activity
MQE35_16530	COG1473	amidohydrolase
MQE35_16545	COG0009	L-threonylcarbamoyladenylate synthase
MQE35_16575	COG1132	(ABC) transporter
MQE35_16580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MQE35_16585	COG0463	Glycosyl transferase, family 2
MQE35_16595	COG0254	rRNA binding
MQE35_16600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MQE35_16610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MQE35_16640	COG1393	Belongs to the ArsC family
MQE35_16650	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
MQE35_16665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MQE35_16680	COG0156	8-amino-7-oxononanoate synthase activity
MQE35_16690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MQE35_16725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MQE35_16730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MQE35_16745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MQE35_16810	COG1858	cytochrome C peroxidase
MQE35_16820	COG1136	(ABC) transporter
MQE35_16825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MQE35_16830	COG0302	gtp cyclohydrolase
MQE35_16840	COG4447	cellulose binding
MQE35_16860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MQE35_16865	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MQE35_16875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MQE35_16880	COG4771	TonB-dependent receptor
MQE35_16910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MQE35_16920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MQE35_16925	COG0456	acetyltransferase
MQE35_16930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MQE35_16935	COG0131	Imidazoleglycerol-phosphate dehydratase
MQE35_16945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MQE35_16950	COG0107	imidazoleglycerol-phosphate synthase activity
MQE35_16955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MQE35_16955	COG0140	phosphoribosyl-ATP diphosphatase activity
MQE35_16965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MQE35_16975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MQE35_16990	COG0022	dehydrogenase e1 component
MQE35_17005	COG1611	Belongs to the LOG family
MQE35_17010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MQE35_17030	COG0405	Gamma-glutamyltransferase
MQE35_17040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MQE35_17045	COG1560	Kdo2-lipid A biosynthetic process
MQE35_17060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MQE35_17070	COG0247	lactate metabolic process
MQE35_17070	COG0277	FAD linked oxidase domain protein
MQE35_17080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MQE35_17090	COG1073	alpha beta
MQE35_17095	COG1629	transport
MQE35_17095	COG4206	TonB-dependent receptor
MQE35_17100	COG3011	Protein conserved in bacteria
MQE35_17110	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MQE35_17120	COG0300	oxidoreductase activity
MQE35_17130	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MQE35_17140	COG1193	negative regulation of DNA recombination
MQE35_17145	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MQE35_17160	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MQE35_17165	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MQE35_17205	COG2217	Heavy metal translocating P-type atpase
MQE35_17225	COG1522	sequence-specific DNA binding
MQE35_17280	COG1858	cytochrome C peroxidase
MQE35_17315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MQE35_17335	COG0798	PFAM Bile acid sodium symporter
MQE35_17380	COG1690	Belongs to the RtcB family
MQE35_17385	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MQE35_17495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MQE35_17500	COG0210	DNA helicase
MQE35_17505	COG0490	domain, Protein
MQE35_17505	COG0471	metal ion transport
MQE35_17545	COG0589	response to stress
MQE35_17560	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_17565	COG0612	Peptidase, M16
MQE35_17570	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MQE35_17580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MQE35_17585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MQE35_17590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MQE35_17590	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MQE35_17595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MQE35_17600	COG1078	dGTPase activity
MQE35_17605	COG2204	response regulator
MQE35_17610	COG0802	atpase or kinase
MQE35_17625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MQE35_17640	COG0010	Belongs to the arginase family
MQE35_17660	COG2878	Part of a membrane complex involved in electron transport
MQE35_17660	COG1245	4Fe-4S binding domain
MQE35_17665	COG4656	Part of a membrane complex involved in electron transport
MQE35_17670	COG4658	electron transport chain
MQE35_17675	COG4659	FMN binding
MQE35_17680	COG4660	Part of a membrane complex involved in electron transport
MQE35_17685	COG4657	Part of a membrane complex involved in electron transport
MQE35_17705	COG1028	Short-chain dehydrogenase reductase Sdr
MQE35_17710	COG1733	regulation of RNA biosynthetic process
MQE35_17715	COG1013	pyruvate-flavodoxin oxidoreductase activity
MQE35_17720	COG0674	pyruvate-flavodoxin oxidoreductase activity
MQE35_17720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MQE35_17725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MQE35_17730	COG0674	pyruvate-flavodoxin oxidoreductase activity
MQE35_17730	COG1013	pyruvate-flavodoxin oxidoreductase activity
MQE35_17730	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MQE35_17730	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MQE35_17740	COG2318	DinB family
MQE35_17770	COG1522	sequence-specific DNA binding
MQE35_17790	COG0861	Integral membrane protein TerC family
MQE35_17795	COG0657	acetylesterase activity
MQE35_17795	COG2755	lipolytic protein G-D-S-L family
MQE35_17800	COG3250	beta-galactosidase activity
MQE35_17885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MQE35_17895	COG1408	metallophosphoesterase
MQE35_17900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MQE35_17920	COG0746	molybdenum cofactor guanylyltransferase activity
MQE35_17925	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MQE35_17955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MQE35_17980	COG0066	3-isopropylmalate dehydratase activity
MQE35_17985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MQE35_18005	COG2211	Major facilitator Superfamily
MQE35_18020	COG1012	belongs to the aldehyde dehydrogenase family
MQE35_18040	COG1045	serine acetyltransferase
MQE35_18050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MQE35_18055	COG0598	Magnesium transport protein CorA
MQE35_18060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MQE35_18085	COG0542	response to heat
MQE35_18095	COG1309	transcriptional regulator
MQE35_18105	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MQE35_18110	COG0813	purine-nucleoside phosphorylase activity
MQE35_18125	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MQE35_18145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MQE35_18150	COG0673	inositol 2-dehydrogenase activity
MQE35_18160	COG1250	3-hydroxyacyl-CoA dehydrogenase
MQE35_18175	COG0322	excinuclease ABC activity
MQE35_18185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MQE35_18190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MQE35_18205	COG2610	gluconate transmembrane transporter activity
MQE35_18265	COG0237	dephospho-CoA kinase activity
MQE35_18280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MQE35_18285	COG0497	DNA recombination
MQE35_18310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MQE35_18320	COG0737	Belongs to the 5'-nucleotidase family
MQE35_18325	COG0737	Belongs to the 5'-nucleotidase family
MQE35_18335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MQE35_18345	COG1611	Belongs to the LOG family
MQE35_18350	COG2890	protein-(glutamine-N5) methyltransferase activity
MQE35_18355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MQE35_18355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MQE35_18360	COG1011	Hydrolase
MQE35_18365	COG0697	spore germination
MQE35_18370	COG1739	Uncharacterized protein family UPF0029
MQE35_18375	COG0824	Thioesterase