locus-tag	class	description
AM10699_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AM10699_00020	COG0592	DNA-directed DNA polymerase activity
AM10699_00060	COG0463	Glycosyl transferase, family 2
AM10699_00070	COG0745	RESPONSE REGULATOR receiver
AM10699_00080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM10699_00090	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AM10699_00100	COG2211	Major facilitator Superfamily
AM10699_00120	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_00170	COG1012	belongs to the aldehyde dehydrogenase family
AM10699_00200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM10699_00250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AM10699_00280	COG4251	negative regulation of phosphorylation
AM10699_00300	COG1994	Peptidase M50
AM10699_00310	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM10699_00340	COG2027	D-alanyl-D-alanine carboxypeptidase
AM10699_00470	COG0681	Belongs to the peptidase S26 family
AM10699_00490	COG0129	dihydroxy-acid dehydratase activity
AM10699_00500	COG3328	transposase activity
AM10699_00550	COG3903	Transcriptional regulator
AM10699_00550	COG2319	Wd-40 repeat
AM10699_00560	COG0824	Thioesterase
AM10699_00620	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AM10699_00630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM10699_00650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AM10699_00670	COG3842	ATPase activity
AM10699_00680	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_00680	COG0515	serine threonine protein kinase
AM10699_00690	COG0629	single-stranded DNA binding
AM10699_00700	COG0628	permease
AM10699_00710	COG0752	glycyl-tRNA synthetase alpha subunit
AM10699_00770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM10699_00810	COG0316	Belongs to the HesB IscA family
AM10699_00880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM10699_00890	COG2274	protein secretion by the type I secretion system
AM10699_00940	COG4978	Transcriptional regulator
AM10699_00940	COG0789	Transcriptional regulator
AM10699_00970	COG1716	ATPase activity
AM10699_00980	COG3266	domain, Protein
AM10699_00980	COG0515	serine threonine protein kinase
AM10699_01020	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AM10699_01020	COG2273	Hydrolase Family 16
AM10699_01040	COG0438	transferase activity, transferring glycosyl groups
AM10699_01050	COG0659	secondary active sulfate transmembrane transporter activity
AM10699_01060	COG0475	glutathione-regulated potassium exporter activity
AM10699_01070	COG1006	Multisubunit Na H antiporter MnhC subunit
AM10699_01080	COG0651	ATP synthesis coupled electron transport
AM10699_01160	COG2146	nitrite reductase [NAD(P)H] activity
AM10699_01170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM10699_01190	COG0515	serine threonine protein kinase
AM10699_01220	COG0459	protein refolding
AM10699_01260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM10699_01370	COG0745	RESPONSE REGULATOR receiver
AM10699_01380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM10699_01390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM10699_01400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_01420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_01460	COG0745	RESPONSE REGULATOR receiver
AM10699_01470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM10699_01470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM10699_01480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM10699_01540	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM10699_01540	COG0596	Alpha beta hydrolase
AM10699_01560	COG3852	Histidine kinase
AM10699_01570	COG0492	ferredoxin-NADP+ reductase activity
AM10699_01590	COG2319	Wd-40 repeat
AM10699_01590	COG3903	Transcriptional regulator
AM10699_01670	COG3328	transposase activity
AM10699_01750	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM10699_01880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM10699_01940	COG0251	oxidation-reduction process
AM10699_01970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM10699_01970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM10699_02030	COG0028	Belongs to the TPP enzyme family
AM10699_02050	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AM10699_02080	COG0469	pyruvate kinase activity
AM10699_02090	COG1959	2 iron, 2 sulfur cluster binding
AM10699_02180	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AM10699_02190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AM10699_02210	COG5002	protein histidine kinase activity
AM10699_02210	COG5001	Diguanylate cyclase
AM10699_02220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM10699_02240	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM10699_02250	COG0649	NAD binding
AM10699_02280	COG0515	serine threonine protein kinase
AM10699_02280	COG3266	domain, Protein
AM10699_02290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM10699_02320	COG2211	Major facilitator Superfamily
AM10699_02330	COG1722	exodeoxyribonuclease VII activity
AM10699_02340	COG1570	exodeoxyribonuclease VII activity
AM10699_02350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM10699_02360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM10699_02370	COG1120	ATPase activity
AM10699_02380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM10699_02390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM10699_02410	COG0492	ferredoxin-NADP+ reductase activity
AM10699_02440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM10699_02450	COG4771	TonB-dependent receptor
AM10699_02540	COG3588	fructose-bisphosphate aldolase
AM10699_02560	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM10699_02600	COG2207	Transcriptional regulator
AM10699_02610	COG4771	TonB-dependent receptor
AM10699_02640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM10699_02700	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM10699_02720	COG4607	ABC-type enterochelin transport system periplasmic component
AM10699_02760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM10699_02830	COG0783	Belongs to the Dps family
AM10699_02840	COG0848	biopolymer transport protein
AM10699_02850	COG0811	peptide transport
AM10699_02870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM10699_02880	COG1120	ATPase activity
AM10699_02890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AM10699_02920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM10699_02990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AM10699_03000	COG0052	Belongs to the universal ribosomal protein uS2 family
AM10699_03010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM10699_03060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM10699_03070	COG0768	penicillin binding
AM10699_03080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM10699_03140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AM10699_03150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM10699_03160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AM10699_03170	COG0544	peptidyl-prolyl cis-trans isomerase activity
AM10699_03180	COG0740	serine-type endopeptidase activity
AM10699_03190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AM10699_03210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM10699_03230	COG5002	protein histidine kinase activity
AM10699_03230	COG5001	Diguanylate cyclase
AM10699_03240	COG1193	negative regulation of DNA recombination
AM10699_03280	COG5002	protein histidine kinase activity
AM10699_03300	COG0745	RESPONSE REGULATOR receiver
AM10699_03310	COG0789	Transcriptional regulator
AM10699_03340	COG2205	protein histidine kinase activity
AM10699_03360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM10699_03390	COG0288	reversible hydration of carbon dioxide
AM10699_03410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM10699_03460	COG5002	protein histidine kinase activity
AM10699_03470	COG0745	RESPONSE REGULATOR receiver
AM10699_03530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM10699_03540	COG0581	inorganic phosphate transmembrane transporter activity
AM10699_03550	COG0573	inorganic phosphate transmembrane transporter activity
AM10699_03560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM10699_03570	COG0640	Transcriptional regulator
AM10699_03620	COG2319	Wd-40 repeat
AM10699_03620	COG4249	Peptidase C14 caspase catalytic subunit p20
AM10699_03630	COG3706	GGDEF domain
AM10699_03630	COG4251	negative regulation of phosphorylation
AM10699_03630	COG2203	Gaf domain
AM10699_03630	COG5001	Diguanylate cyclase
AM10699_03650	COG3540	Alkaline phosphatase
AM10699_03730	COG1748	Saccharopine dehydrogenase
AM10699_03740	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM10699_03760	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AM10699_03800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM10699_03810	COG0204	Acyl-transferase
AM10699_03810	COG0318	PFAM AMP-dependent synthetase and ligase
AM10699_03830	COG0242	peptide deformylase activity
AM10699_03900	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AM10699_03910	COG0010	Belongs to the arginase family
AM10699_03940	COG0154	amidase activity
AM10699_03960	COG0004	ammonium transporteR
AM10699_03970	COG0004	ammonium transporteR
AM10699_04030	COG2720	vancomycin resistance protein
AM10699_04070	COG2385	sporulation resulting in formation of a cellular spore
AM10699_04130	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM10699_04140	COG3540	Alkaline phosphatase
AM10699_04240	COG2124	cytochrome p450
AM10699_04260	COG2815	serine threonine protein kinase
AM10699_04260	COG0515	serine threonine protein kinase
AM10699_04270	COG2204	response regulator
AM10699_04280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM10699_04280	COG4191	Histidine kinase
AM10699_04290	COG3437	response regulator, receiver
AM10699_04290	COG0784	Response regulator, receiver
AM10699_04300	COG5001	Diguanylate cyclase
AM10699_04300	COG4251	negative regulation of phosphorylation
AM10699_04300	COG2203	Gaf domain
AM10699_04300	COG3706	GGDEF domain
AM10699_04310	COG0116	Belongs to the methyltransferase superfamily
AM10699_04320	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM10699_04340	COG0822	iron-sulfur transferase activity
AM10699_04360	COG0371	Dehydrogenase
AM10699_04370	COG0436	Aminotransferase
AM10699_04380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM10699_04390	COG0569	domain protein
AM10699_04400	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM10699_04420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM10699_04430	COG0406	alpha-ribazole phosphatase activity
AM10699_04500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM10699_04510	COG0268	Binds directly to 16S ribosomal RNA
AM10699_04520	COG0084	hydrolase, TatD family'
AM10699_04530	COG0085	RNA polymerase activity
AM10699_04540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM10699_04550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AM10699_04560	COG2267	carboxylic ester hydrolase activity
AM10699_04570	COG0534	Mate efflux family protein
AM10699_04600	COG2022	thiamine diphosphate biosynthetic process
AM10699_04630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM10699_04710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM10699_04730	COG2226	methyltransferase
AM10699_04790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM10699_04870	COG0673	inositol 2-dehydrogenase activity
AM10699_04950	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AM10699_04960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AM10699_04970	COG0799	negative regulation of ribosome biogenesis
AM10699_05010	COG0628	permease
AM10699_05040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM10699_05060	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_05060	COG0515	serine threonine protein kinase
AM10699_05070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM10699_05080	COG1215	transferase activity, transferring glycosyl groups
AM10699_05100	COG3769	mannosylglycerate metabolic process
AM10699_05120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AM10699_05160	COG2045	Belongs to the ComB family
AM10699_05170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM10699_05200	COG1732	Glycine betaine
AM10699_05230	COG2082	Precorrin-8x methylmutase
AM10699_05260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM10699_05280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM10699_05310	COG0483	inositol monophosphate 1-phosphatase activity
AM10699_05330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM10699_05350	COG0300	oxidoreductase activity
AM10699_05370	COG0735	belongs to the Fur family
AM10699_05380	COG0678	peroxiredoxin activity
AM10699_05390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM10699_05400	COG0723	plastoquinol--plastocyanin reductase activity
AM10699_05480	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AM10699_05510	COG3328	transposase activity
AM10699_05610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM10699_05640	COG3128	pkhd-type hydroxylase
AM10699_05650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM10699_05660	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AM10699_05680	COG2203	Gaf domain
AM10699_05680	COG3706	GGDEF domain
AM10699_05680	COG4251	negative regulation of phosphorylation
AM10699_05680	COG5001	Diguanylate cyclase
AM10699_05690	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AM10699_05720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AM10699_05730	COG0589	response to stress
AM10699_05740	COG0659	secondary active sulfate transmembrane transporter activity
AM10699_05750	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AM10699_05760	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AM10699_05790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM10699_05800	COG0745	RESPONSE REGULATOR receiver
AM10699_05820	COG0861	Integral membrane protein TerC family
AM10699_05860	COG0105	UTP biosynthetic process
AM10699_05870	COG0671	phosphoesterase, PA-phosphatase related
AM10699_05920	COG2198	Histidine kinase
AM10699_05920	COG0643	Histidine kinase
AM10699_05920	COG0784	Response regulator, receiver
AM10699_05930	COG0840	transmembrane signaling receptor activity
AM10699_05950	COG0745	RESPONSE REGULATOR receiver
AM10699_05960	COG0784	Response regulator, receiver
AM10699_05980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM10699_06020	COG1876	peptidase activity
AM10699_06030	COG3266	domain, Protein
AM10699_06030	COG0515	serine threonine protein kinase
AM10699_06040	COG4948	Mandelate Racemase Muconate Lactonizing
AM10699_06050	COG0318	PFAM AMP-dependent synthetase and ligase
AM10699_06080	COG1396	sequence-specific DNA binding
AM10699_06110	COG3239	Fatty acid desaturase
AM10699_06240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM10699_06270	COG1132	(ABC) transporter
AM10699_06330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM10699_06340	COG0552	protein localization to endoplasmic reticulum
AM10699_06350	COG2208	phosphoserine phosphatase activity
AM10699_06370	COG0006	proline dipeptidase activity
AM10699_06390	COG0730	response to heat
AM10699_06410	COG0308	aminopeptidase N
AM10699_06470	COG0432	Pfam Uncharacterised protein family UPF0047
AM10699_06580	COG1940	carbohydrate kinase activity
AM10699_06640	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM10699_06660	COG2226	methyltransferase
AM10699_06700	COG2319	Wd-40 repeat
AM10699_06700	COG3903	Transcriptional regulator
AM10699_06710	COG0667	Aldo Keto reductase
AM10699_06740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM10699_06760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AM10699_06820	COG3263	regulation of cellular component size
AM10699_06830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM10699_06860	COG2197	response regulator
AM10699_06870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM10699_06880	COG0784	Response regulator, receiver
AM10699_06880	COG2198	Histidine kinase
AM10699_06880	COG2205	protein histidine kinase activity
AM10699_06900	COG0701	Predicted permease
AM10699_06920	COG0343	queuine tRNA-ribosyltransferase activity
AM10699_06940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM10699_06940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM10699_06950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM10699_07070	COG1201	RNA secondary structure unwinding
AM10699_07080	COG4251	negative regulation of phosphorylation
AM10699_07090	COG4251	negative regulation of phosphorylation
AM10699_07100	COG0784	Response regulator, receiver
AM10699_07110	COG5002	protein histidine kinase activity
AM10699_07110	COG5001	Diguanylate cyclase
AM10699_07120	COG0484	heat shock protein binding
AM10699_07140	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM10699_07150	COG2081	HI0933 family
AM10699_07160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM10699_07170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AM10699_07190	COG2010	Cytochrome c
AM10699_07200	COG2010	Cytochrome c
AM10699_07210	COG2010	Cytochrome c
AM10699_07230	COG2329	Antibiotic biosynthesis monooxygenase
AM10699_07240	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_07260	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AM10699_07300	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM10699_07390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM10699_07440	COG0515	serine threonine protein kinase
AM10699_07440	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_07470	COG0745	RESPONSE REGULATOR receiver
AM10699_07480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM10699_07490	COG1194	a g-specific adenine glycosylase
AM10699_07530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_07540	COG2091	lysine biosynthetic process via aminoadipic acid
AM10699_07550	COG0426	domain, Protein
AM10699_07550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM10699_07610	COG0511	ligase activity, forming carbon-carbon bonds
AM10699_07620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AM10699_07640	COG0745	RESPONSE REGULATOR receiver
AM10699_07650	COG3932	Exopolysaccharide synthesis, ExoD
AM10699_07660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM10699_07700	COG0181	hydroxymethylbilane synthase activity
AM10699_07720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM10699_07730	COG0205	6-phosphofructokinase activity
AM10699_07740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM10699_07770	COG2319	Wd-40 repeat
AM10699_07770	COG3903	Transcriptional regulator
AM10699_07790	COG0515	serine threonine protein kinase
AM10699_07810	COG0792	nuclease activity
AM10699_07830	COG0747	negative chemotaxis
AM10699_07840	COG0633	Ferredoxin
AM10699_07920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AM10699_07930	COG1555	photosystem II stabilization
AM10699_07950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM10699_07980	COG0330	HflC and HflK could
AM10699_08050	COG0501	Belongs to the peptidase M48B family
AM10699_08060	COG0148	phosphopyruvate hydratase activity
AM10699_08070	COG0346	lactoylglutathione lyase activity
AM10699_08080	COG3659	wide pore channel activity
AM10699_08090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AM10699_08100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AM10699_08110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AM10699_08130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM10699_08140	COG0483	inositol monophosphate 1-phosphatase activity
AM10699_08150	COG0484	heat shock protein binding
AM10699_08160	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AM10699_08170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM10699_08220	COG0436	Aminotransferase
AM10699_08230	COG1842	Phage shock protein A
AM10699_08250	COG0667	Aldo Keto reductase
AM10699_08260	COG0372	Belongs to the citrate synthase family
AM10699_08350	COG0596	Alpha beta hydrolase
AM10699_08400	COG0384	phenazine biosynthesis protein PhzF
AM10699_08420	COG0438	transferase activity, transferring glycosyl groups
AM10699_08510	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
AM10699_08520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM10699_08530	COG0515	serine threonine protein kinase
AM10699_08560	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AM10699_08570	COG5322	oxidoreductase activity
AM10699_08610	COG2226	methyltransferase
AM10699_08630	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AM10699_08650	COG0745	RESPONSE REGULATOR receiver
AM10699_08660	COG4581	dead DEAH box helicase
AM10699_08670	COG2198	Histidine kinase
AM10699_08670	COG0643	Histidine kinase
AM10699_08680	COG0840	transmembrane signaling receptor activity
AM10699_08720	COG1573	uracil-dna glycosylase
AM10699_08750	COG0750	zinc metalloprotease
AM10699_08760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM10699_08770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AM10699_08800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AM10699_08810	COG0215	cysteine-tRNA ligase activity
AM10699_08830	COG1716	ATPase activity
AM10699_08830	COG5001	Diguanylate cyclase
AM10699_08850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM10699_08860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM10699_08880	COG3328	transposase activity
AM10699_09000	COG3265	gluconokinase activity
AM10699_09020	COG1121	(ABC) transporter
AM10699_09030	COG0228	four-way junction DNA binding
AM10699_09050	COG1702	phosphate starvation-inducible protein PhoH
AM10699_09080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM10699_09090	COG0336	Belongs to the RNA methyltransferase TrmD family
AM10699_09100	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AM10699_09190	COG0702	epimerase
AM10699_09220	COG2183	response to ionizing radiation
AM10699_09260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AM10699_09340	COG0006	proline dipeptidase activity
AM10699_09350	COG0438	transferase activity, transferring glycosyl groups
AM10699_09360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM10699_09370	COG0456	acetyltransferase
AM10699_09380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM10699_09430	COG0697	spore germination
AM10699_09470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM10699_09490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AM10699_09580	COG0697	spore germination
AM10699_09590	COG2124	cytochrome p450
AM10699_09620	COG0347	Belongs to the P(II) protein family
AM10699_09650	COG2084	Dehydrogenase
AM10699_09680	COG0583	DNA-binding transcription factor activity
AM10699_09770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM10699_09780	COG1285	pathogenesis
AM10699_09830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM10699_09830	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AM10699_09940	COG1366	Belongs to the anti-sigma-factor antagonist family
AM10699_09990	COG2340	Cysteine-rich secretory protein family
AM10699_10000	COG2304	oxidoreductase activity
AM10699_10010	COG0640	Transcriptional regulator
AM10699_10020	COG2912	Transglutaminase-like superfamily
AM10699_10040	COG5002	protein histidine kinase activity
AM10699_10060	COG0557	exoribonuclease II activity
AM10699_10070	COG0704	Plays a role in the regulation of phosphate uptake
AM10699_10190	COG0137	argininosuccinate synthase activity
AM10699_10210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM10699_10240	COG1077	Cell shape determining protein MreB Mrl
AM10699_10250	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AM10699_10290	COG1492	cobalamin metabolic process
AM10699_10310	COG3956	TIGRFAM MazG family protein
AM10699_10360	COG2720	vancomycin resistance protein
AM10699_10390	COG0166	Belongs to the GPI family
AM10699_10400	COG1716	ATPase activity
AM10699_10420	COG2205	protein histidine kinase activity
AM10699_10430	COG3022	response to hydroperoxide
AM10699_10480	COG0784	Response regulator, receiver
AM10699_10480	COG2198	Histidine kinase
AM10699_10480	COG5002	protein histidine kinase activity
AM10699_10510	COG1132	(ABC) transporter
AM10699_10590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM10699_10590	COG2022	thiamine diphosphate biosynthetic process
AM10699_10620	COG2319	Wd-40 repeat
AM10699_10620	COG4249	Peptidase C14 caspase catalytic subunit p20
AM10699_10710	COG2197	response regulator
AM10699_10850	COG4251	negative regulation of phosphorylation
AM10699_10850	COG3706	GGDEF domain
AM10699_10850	COG5001	Diguanylate cyclase
AM10699_10850	COG2203	Gaf domain
AM10699_10860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM10699_10860	COG0072	phenylalanine-tRNA ligase activity
AM10699_10900	COG0515	serine threonine protein kinase
AM10699_10910	COG0515	serine threonine protein kinase
AM10699_10920	COG0515	serine threonine protein kinase
AM10699_10930	COG0515	serine threonine protein kinase
AM10699_10950	COG0515	serine threonine protein kinase
AM10699_10960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM10699_11010	COG2890	protein-(glutamine-N5) methyltransferase activity
AM10699_11030	COG0686	Belongs to the AlaDH PNT family
AM10699_11070	COG2852	Protein conserved in bacteria
AM10699_11110	COG3210	domain, Protein
AM10699_11120	COG0612	Peptidase, M16
AM10699_11140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM10699_11150	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_11160	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AM10699_11170	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AM10699_11190	COG1691	(AIR) carboxylase
AM10699_11210	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AM10699_11220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM10699_11230	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
AM10699_11250	COG1187	pseudouridine synthase activity
AM10699_11260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM10699_11290	COG0134	indole-3-glycerol-phosphate synthase activity
AM10699_11300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM10699_11310	COG0517	IMP dehydrogenase activity
AM10699_11310	COG1994	Peptidase M50
AM10699_11330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_11350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM10699_11360	COG0284	orotidine-5'-phosphate decarboxylase activity
AM10699_11370	COG2003	Belongs to the UPF0758 family
AM10699_11380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM10699_11410	COG3264	Mechanosensitive ion channel
AM10699_11410	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM10699_11420	COG1304	FMN binding
AM10699_11440	COG0210	DNA helicase
AM10699_11470	COG0531	amino acid
AM10699_11510	COG0746	molybdenum cofactor guanylyltransferase activity
AM10699_11520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM10699_11530	COG0583	DNA-binding transcription factor activity
AM10699_11550	COG0149	triose-phosphate isomerase activity
AM10699_11570	COG1132	(ABC) transporter
AM10699_11580	COG0741	lytic transglycosylase activity
AM10699_11580	COG0739	heme binding
AM10699_11580	COG1196	nuclear chromosome segregation
AM10699_11680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM10699_11680	COG1333	cytochrome c biogenesis protein
AM10699_11750	COG0459	protein refolding
AM10699_11760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AM10699_11770	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AM10699_11790	COG0165	Argininosuccinate lyase
AM10699_11810	COG0395	ABC-type sugar transport system, permease component
AM10699_11840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AM10699_11870	COG1214	PFAM Peptidase M22, glycoprotease
AM10699_11880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM10699_11900	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AM10699_11910	COG0519	Catalyzes the synthesis of GMP from XMP
AM10699_11910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM10699_11930	COG2205	protein histidine kinase activity
AM10699_11930	COG2202	Pas domain
AM10699_12040	COG0534	Mate efflux family protein
AM10699_12060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AM10699_12100	COG1132	(ABC) transporter
AM10699_12120	COG3258	Cytochrome c
AM10699_12150	COG0805	protein transport
AM10699_12210	COG0793	Belongs to the peptidase S41A family
AM10699_12220	COG1346	cytolysis
AM10699_12230	COG1380	Effector of murein hydrolase LrgA
AM10699_12240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM10699_12370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM10699_12430	COG2319	Wd-40 repeat
AM10699_12430	COG1672	PFAM Archaeal ATPase
AM10699_12440	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_12550	COG0519	Catalyzes the synthesis of GMP from XMP
AM10699_12580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AM10699_12590	COG1372	Participates in initiation and elongation during chromosome replication
AM10699_12590	COG0187	DNA topoisomerase II activity
AM10699_12620	COG0170	dolichyl monophosphate biosynthetic process
AM10699_12650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AM10699_12660	COG0023	Translation Initiation Factor
AM10699_12710	COG0788	formyltetrahydrofolate deformylase activity
AM10699_12770	COG1070	Carbohydrate kinase
AM10699_12910	COG1716	ATPase activity
AM10699_12910	COG5001	Diguanylate cyclase
AM10699_12920	COG0018	arginyl-trna synthetase
AM10699_12930	COG2226	methyltransferase
AM10699_12940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM10699_12950	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_12950	COG0515	serine threonine protein kinase
AM10699_12980	COG1316	TRANSCRIPTIONal
AM10699_13000	COG1063	alcohol dehydrogenase
AM10699_13010	COG1051	belongs to the nudix hydrolase family
AM10699_13020	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AM10699_13050	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AM10699_13060	COG0539	negative regulation of cytoplasmic translation
AM10699_13070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AM10699_13100	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AM10699_13130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM10699_13140	COG2046	Belongs to the sulfate adenylyltransferase family
AM10699_13160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM10699_13180	COG1490	D-aminoacyl-tRNA deacylase activity
AM10699_13190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM10699_13210	COG5001	Diguanylate cyclase
AM10699_13210	COG2203	Gaf domain
AM10699_13210	COG4251	negative regulation of phosphorylation
AM10699_13210	COG3706	GGDEF domain
AM10699_13220	COG3240	lipase activity
AM10699_13250	COG1215	transferase activity, transferring glycosyl groups
AM10699_13280	COG0857	belongs to the CobB CobQ family
AM10699_13300	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AM10699_13330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM10699_13340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_13370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_13380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_13400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM10699_13410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM10699_13410	COG0662	Cupin 2, conserved barrel domain protein
AM10699_13450	COG0259	pyridoxamine-phosphate oxidase activity
AM10699_13530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM10699_13550	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AM10699_13590	COG2319	Wd-40 repeat
AM10699_13590	COG1672	PFAM Archaeal ATPase
AM10699_13630	COG0515	serine threonine protein kinase
AM10699_13640	COG0583	DNA-binding transcription factor activity
AM10699_13650	COG0157	Belongs to the NadC ModD family
AM10699_13660	COG1845	cytochrome c oxidase, subunit III
AM10699_13670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM10699_13680	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM10699_13700	COG0109	protoheme IX farnesyltransferase activity
AM10699_13710	COG1131	(ABC) transporter
AM10699_13760	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM10699_13780	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AM10699_13790	COG1381	Involved in DNA repair and RecF pathway recombination
AM10699_13810	COG0438	transferase activity, transferring glycosyl groups
AM10699_13810	COG0297	glycogen (starch) synthase activity
AM10699_13820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AM10699_13870	COG1543	Belongs to the glycosyl hydrolase 57 family
AM10699_13880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM10699_13890	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AM10699_13900	COG2894	cell division
AM10699_13910	COG0850	regulation of cytokinetic process
AM10699_13930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AM10699_13950	COG0601	transmembrane transport
AM10699_13960	COG4166	transmembrane transport
AM10699_13980	COG1587	Uroporphyrinogen-III synthase
AM10699_14000	COG1595	DNA-templated transcription, initiation
AM10699_14030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AM10699_14040	COG3239	Fatty acid desaturase
AM10699_14050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM10699_14070	COG0758	DNA mediated transformation
AM10699_14070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM10699_14080	COG0242	peptide deformylase activity
AM10699_14090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AM10699_14100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AM10699_14110	COG0793	Belongs to the peptidase S41A family
AM10699_14120	COG1078	dGTPase activity
AM10699_14140	COG0328	RNA-DNA hybrid ribonuclease activity
AM10699_14150	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AM10699_14170	COG1836	PFAM Integral membrane protein DUF92
AM10699_14200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AM10699_14360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AM10699_14370	COG0088	Forms part of the polypeptide exit tunnel
AM10699_14380	COG0089	rRNA binding
AM10699_14390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AM10699_14400	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AM10699_14410	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AM10699_14420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AM10699_14430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AM10699_14440	COG0255	Belongs to the universal ribosomal protein uL29 family
AM10699_14450	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AM10699_14460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AM10699_14470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AM10699_14480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AM10699_14490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AM10699_14500	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AM10699_14510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AM10699_14520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AM10699_14530	COG0200	Binds to the 23S rRNA
AM10699_14540	COG0201	protein transport
AM10699_14550	COG0563	adenylate kinase activity
AM10699_14560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AM10699_14700	COG4566	intracellular signal transduction
AM10699_14710	COG2897	thiosulfate sulfurtransferase activity
AM10699_14740	COG2852	Protein conserved in bacteria
AM10699_14760	COG1672	PFAM Archaeal ATPase
AM10699_14760	COG2319	Wd-40 repeat
AM10699_14890	COG2255	four-way junction helicase activity
AM10699_14900	COG1690	Belongs to the RtcB family
AM10699_14910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM10699_14950	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AM10699_14960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM10699_14980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_15020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM10699_15030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AM10699_15040	COG1104	cysteine desulfurase activity
AM10699_15060	COG5001	Diguanylate cyclase
AM10699_15270	COG2264	protein methyltransferase activity
AM10699_15310	COG0113	porphobilinogen synthase activity
AM10699_15330	COG0133	tryptophan synthase activity
AM10699_15380	COG0557	exoribonuclease II activity
AM10699_15390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AM10699_15440	COG1064	alcohol dehydrogenase
AM10699_15470	COG1324	tolerance protein
AM10699_15510	COG1562	ergosterol biosynthetic process
AM10699_15520	COG0493	'glutamate synthase
AM10699_15520	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AM10699_15540	COG2226	methyltransferase
AM10699_15600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM10699_15620	COG0640	Transcriptional regulator
AM10699_15630	COG3118	belongs to the thioredoxin family
AM10699_15640	COG1902	pentaerythritol trinitrate reductase activity
AM10699_15670	COG1879	ABC-type sugar transport system periplasmic component
AM10699_15680	COG1657	PFAM Prenyltransferase squalene oxidase
AM10699_15710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AM10699_15720	COG0793	Belongs to the peptidase S41A family
AM10699_15730	COG0438	transferase activity, transferring glycosyl groups
AM10699_15740	COG1429	ligase activity, forming nitrogen-metal bonds
AM10699_15750	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AM10699_15770	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AM10699_15790	COG0612	Peptidase, M16
AM10699_15800	COG0612	Peptidase, M16
AM10699_15820	COG0489	protein tyrosine kinase activity
AM10699_15820	COG3206	protein involved in exopolysaccharide biosynthesis
AM10699_15890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AM10699_15910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM10699_16010	COG1505	serine-type exopeptidase activity
AM10699_16020	COG1505	serine-type exopeptidase activity
AM10699_16060	COG0352	thiamine-phosphate diphosphorylase activity
AM10699_16070	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM10699_16090	COG3063	Type IV pilus biogenesis stability protein PilW
AM10699_16100	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM10699_16110	COG0271	Belongs to the BolA IbaG family
AM10699_16140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AM10699_16160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM10699_16160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM10699_16180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM10699_16190	COG0848	biopolymer transport protein
AM10699_16200	COG0811	peptide transport
AM10699_16220	COG0824	Thioesterase
AM10699_16230	COG1672	PFAM Archaeal ATPase
AM10699_16240	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AM10699_16250	COG0681	Belongs to the peptidase S26 family
AM10699_16260	COG0142	geranyltranstransferase activity
AM10699_16270	COG0492	ferredoxin-NADP+ reductase activity
AM10699_16290	COG0572	uridine kinase
AM10699_16300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM10699_16310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AM10699_16330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_16350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM10699_16360	COG0589	response to stress
AM10699_16460	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AM10699_16490	COG0586	Pfam SNARE associated Golgi protein
AM10699_16550	COG2084	Dehydrogenase
AM10699_16630	COG2197	response regulator
AM10699_16650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AM10699_16660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM10699_16670	COG1121	(ABC) transporter
AM10699_16770	COG3063	Type IV pilus biogenesis stability protein PilW
AM10699_16840	COG0793	Belongs to the peptidase S41A family
AM10699_16860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM10699_16890	COG0723	plastoquinol--plastocyanin reductase activity
AM10699_16900	COG3706	GGDEF domain
AM10699_16900	COG5001	Diguanylate cyclase
AM10699_16900	COG4251	negative regulation of phosphorylation
AM10699_16900	COG2203	Gaf domain
AM10699_16920	COG5001	Diguanylate cyclase
AM10699_16920	COG4251	negative regulation of phosphorylation
AM10699_16920	COG3706	GGDEF domain
AM10699_16920	COG2203	Gaf domain
AM10699_16930	COG2234	aminopeptidase activity
AM10699_16990	COG2319	Wd-40 repeat
AM10699_16990	COG1672	PFAM Archaeal ATPase
AM10699_17040	COG0604	alcohol dehydrogenase
AM10699_17050	COG4191	Histidine kinase
AM10699_17130	COG3237	CsbD-like
AM10699_17140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM10699_17160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM10699_17170	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AM10699_17210	COG0039	L-malate dehydrogenase activity
AM10699_17260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM10699_17290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM10699_17300	COG0402	S-adenosylhomocysteine deaminase activity
AM10699_17330	COG0577	efflux transmembrane transporter activity
AM10699_17330	COG1136	(ABC) transporter
AM10699_17340	COG1136	(ABC) transporter
AM10699_17380	COG1555	photosystem II stabilization
AM10699_17390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM10699_17400	COG0517	IMP dehydrogenase activity
AM10699_17400	COG1994	Peptidase M50
AM10699_17410	COG0589	response to stress
AM10699_17430	COG5002	protein histidine kinase activity
AM10699_17450	COG3781	membrane
AM10699_17480	COG0784	Response regulator, receiver
AM10699_17480	COG2198	Histidine kinase
AM10699_17480	COG0643	Histidine kinase
AM10699_17500	COG5002	protein histidine kinase activity
AM10699_17520	COG0668	transmembrane transport
AM10699_17590	COG2205	protein histidine kinase activity
AM10699_17620	COG1090	epimerase
AM10699_17640	COG2201	protein-glutamate methylesterase activity
AM10699_17650	COG0643	Histidine kinase
AM10699_17650	COG2198	Histidine kinase
AM10699_17650	COG0784	Response regulator, receiver
AM10699_17660	COG0840	transmembrane signaling receptor activity
AM10699_17680	COG0784	Response regulator, receiver
AM10699_17690	COG3437	response regulator, receiver
AM10699_17700	COG2226	methyltransferase
AM10699_17720	COG0398	Pfam SNARE associated Golgi protein
AM10699_17730	COG0398	Pfam SNARE associated Golgi protein
AM10699_17790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM10699_17810	COG3266	domain, Protein
AM10699_17810	COG2911	Protein conserved in bacteria
AM10699_17810	COG1361	Conserved repeat domain
AM10699_17830	COG0745	RESPONSE REGULATOR receiver
AM10699_17850	COG1620	l-lactate permease
AM10699_17890	COG0829	nickel cation binding
AM10699_17900	COG0831	urea catabolic process
AM10699_17920	COG0832	Belongs to the urease beta subunit family
AM10699_17930	COG2205	protein histidine kinase activity
AM10699_17930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM10699_17950	COG0804	urea catabolic process
AM10699_18050	COG1132	(ABC) transporter
AM10699_18060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AM10699_18070	COG0033	Phosphoglucomutase
AM10699_18110	COG3328	transposase activity
AM10699_18130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM10699_18170	COG2205	protein histidine kinase activity
AM10699_18170	COG0784	Response regulator, receiver
AM10699_18170	COG2198	Histidine kinase
AM10699_18180	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AM10699_18190	COG0009	L-threonylcarbamoyladenylate synthase
AM10699_18200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AM10699_18250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM10699_18270	COG5002	protein histidine kinase activity
AM10699_18290	COG5433	transposase activity
AM10699_18300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM10699_18310	COG0514	ATP-dependent DNA helicase (RecQ)
AM10699_18340	COG3300	MHYT domain
AM10699_18340	COG5001	Diguanylate cyclase
AM10699_18350	COG2124	cytochrome p450
AM10699_18420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM10699_18430	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AM10699_18440	COG1116	anion transmembrane transporter activity
AM10699_18440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM10699_18450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM10699_18460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM10699_18470	COG0745	RESPONSE REGULATOR receiver
AM10699_18480	COG5002	protein histidine kinase activity
AM10699_18580	COG0515	serine threonine protein kinase
AM10699_18580	COG3266	domain, Protein
AM10699_18610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AM10699_18620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AM10699_18650	COG1077	Cell shape determining protein MreB Mrl
AM10699_18660	COG1175	transmembrane transport
AM10699_18680	COG1716	ATPase activity
AM10699_18690	COG0505	Belongs to the CarA family
AM10699_18700	COG0596	Alpha beta hydrolase
AM10699_18720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM10699_18740	COG1366	Belongs to the anti-sigma-factor antagonist family
AM10699_18760	COG0673	inositol 2-dehydrogenase activity
AM10699_18780	COG0783	Belongs to the Dps family
AM10699_18800	COG3937	granule-associated protein
AM10699_18840	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_18840	COG0515	serine threonine protein kinase
AM10699_18910	COG3268	Saccharopine dehydrogenase
AM10699_18930	COG3657	addiction module killer protein
AM10699_18940	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM10699_18950	COG0756	dUTP diphosphatase activity
AM10699_18970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM10699_18990	COG1716	ATPase activity
AM10699_18990	COG5001	Diguanylate cyclase
AM10699_19000	COG3264	Mechanosensitive ion channel
AM10699_19000	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AM10699_19090	COG2032	superoxide dismutase activity
AM10699_19150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM10699_19170	COG3659	wide pore channel activity
AM10699_19220	COG0501	Belongs to the peptidase M48B family
AM10699_19240	COG0481	GTPase activity
AM10699_19250	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AM10699_19290	COG5002	protein histidine kinase activity
AM10699_19300	COG0745	RESPONSE REGULATOR receiver
AM10699_19320	COG0786	glutamate:sodium symporter activity
AM10699_19330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM10699_19400	COG0714	Associated with various cellular activities
AM10699_19410	COG0714	Associated with various cellular activities
AM10699_19540	COG0438	transferase activity, transferring glycosyl groups
AM10699_19550	COG3903	Transcriptional regulator
AM10699_19550	COG2319	Wd-40 repeat
AM10699_19580	COG1283	sodium-dependent phosphate transmembrane transporter activity
AM10699_19610	COG5002	protein histidine kinase activity
AM10699_19610	COG2205	protein histidine kinase activity
AM10699_19610	COG0784	Response regulator, receiver
AM10699_19680	COG0668	transmembrane transport
AM10699_19770	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AM10699_19780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AM10699_19790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AM10699_19810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM10699_19840	COG0583	DNA-binding transcription factor activity
AM10699_19950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM10699_19970	COG2259	Doxx family
AM10699_19980	COG1372	Participates in initiation and elongation during chromosome replication
AM10699_19980	COG0305	Participates in initiation and elongation during chromosome replication
AM10699_19980	COG1372	Participates in initiation and elongation during chromosome replication
AM10699_19980	COG0305	Participates in initiation and elongation during chromosome replication
AM10699_19990	COG0359	binds to the 23S rRNA
AM10699_20060	COG3266	domain, Protein
AM10699_20060	COG0515	serine threonine protein kinase
AM10699_20080	COG1187	pseudouridine synthase activity
AM10699_20090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AM10699_20100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM10699_20120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AM10699_20130	COG1799	cell septum assembly
AM10699_20140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AM10699_20160	COG3842	ATPase activity
AM10699_20180	COG0596	Alpha beta hydrolase
AM10699_20200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AM10699_20210	COG0739	heme binding
AM10699_20250	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_20260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM10699_20270	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM10699_20280	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM10699_20290	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AM10699_20300	COG4451	ribulose bisphosphate carboxylase, small
AM10699_20300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM10699_20310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM10699_20320	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM10699_20330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM10699_20340	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM10699_20380	COG1803	Methylglyoxal synthase
AM10699_20380	COG1597	lipid kinase activity
AM10699_20500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM10699_20550	COG1444	tRNA N-acetyltransferase activity
AM10699_20580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AM10699_20590	COG1396	sequence-specific DNA binding
AM10699_20600	COG3550	peptidyl-serine autophosphorylation
AM10699_20640	COG1606	tRNA processing
AM10699_20650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AM10699_20670	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AM10699_20730	COG0123	including yeast histone deacetylase and acetoin utilization protein
AM10699_20770	COG2319	Wd-40 repeat
AM10699_20770	COG4249	Peptidase C14 caspase catalytic subunit p20
AM10699_20780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM10699_20790	COG1480	7TM receptor with intracellular HD hydrolase
AM10699_20820	COG0516	GMP reductase activity
AM10699_20820	COG0517	IMP dehydrogenase activity
AM10699_20850	COG3118	belongs to the thioredoxin family
AM10699_20890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_20990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AM10699_21030	COG0617	tRNA 3'-terminal CCA addition
AM10699_21080	COG4977	sequence-specific DNA binding
AM10699_21080	COG1917	Cupin 2, conserved barrel domain protein
AM10699_21090	COG3903	Transcriptional regulator
AM10699_21090	COG2319	Wd-40 repeat
AM10699_21150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM10699_21160	COG0515	serine threonine protein kinase
AM10699_21160	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_21190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_21200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM10699_21220	COG2135	peptidase activity
AM10699_21230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM10699_21270	COG0347	Belongs to the P(II) protein family
AM10699_21290	COG0450	alkyl hydroperoxide reductase
AM10699_21310	COG0194	GDP metabolic process
AM10699_21320	COG2052	Domain of unknown function (DUF370)
AM10699_21330	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AM10699_21390	COG0528	UMP kinase activity
AM10699_21400	COG0233	cytoplasmic translational termination
AM10699_21420	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AM10699_21450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AM10699_21460	COG0193	aminoacyl-tRNA hydrolase activity
AM10699_21480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM10699_21500	COG0346	lactoylglutathione lyase activity
AM10699_21520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM10699_21530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM10699_21540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM10699_21560	COG2048	Heterodisulfide reductase, subunit B
AM10699_21580	COG4999	Histidine kinase
AM10699_21580	COG3850	Histidine kinase
AM10699_21580	COG3437	response regulator, receiver
AM10699_21580	COG2205	protein histidine kinase activity
AM10699_21590	COG0556	nucleotide-excision repair
AM10699_21660	COG5002	protein histidine kinase activity
AM10699_21700	COG1234	tRNA 3'-trailer cleavage
AM10699_21730	COG0297	glycogen (starch) synthase activity
AM10699_21760	COG0438	transferase activity, transferring glycosyl groups
AM10699_21770	COG0438	transferase activity, transferring glycosyl groups
AM10699_21780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM10699_21790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AM10699_21810	COG0793	Belongs to the peptidase S41A family
AM10699_21830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AM10699_21840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM10699_21850	COG0724	RNA recognition motif
AM10699_21860	COG0482	sulfurtransferase activity
AM10699_21890	COG1022	Amp-dependent synthetase and ligase
AM10699_21910	COG1429	ligase activity, forming nitrogen-metal bonds
AM10699_21960	COG0517	IMP dehydrogenase activity
AM10699_21960	COG1994	Peptidase M50
AM10699_21970	COG0095	Lipoate-protein ligase
AM10699_22000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM10699_22010	COG0189	ligase activity
AM10699_22020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM10699_22040	COG4279	zinc finger
AM10699_22070	COG1215	transferase activity, transferring glycosyl groups
AM10699_22100	COG0514	ATP-dependent DNA helicase (RecQ)
AM10699_22150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AM10699_22180	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AM10699_22180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM10699_22220	COG0577	efflux transmembrane transporter activity
AM10699_22240	COG4399	Belongs to the UPF0754 family
AM10699_22250	COG1131	(ABC) transporter
AM10699_22260	COG0631	protein serine/threonine phosphatase activity
AM10699_22270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM10699_22280	COG3937	granule-associated protein
AM10699_22290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM10699_22320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM10699_22320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AM10699_22380	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AM10699_22400	COG5001	Diguanylate cyclase
AM10699_22400	COG5002	protein histidine kinase activity
AM10699_22410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM10699_22450	COG0628	permease
AM10699_22470	COG0003	Pfam Anion-transporting ATPase
AM10699_22480	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_22490	COG0825	malonyl-CoA metabolic process
AM10699_22500	COG0300	oxidoreductase activity
AM10699_22510	COG0302	gtp cyclohydrolase
AM10699_22540	COG2205	protein histidine kinase activity
AM10699_22540	COG0784	Response regulator, receiver
AM10699_22590	COG0418	dihydroorotase activity
AM10699_22610	COG2994	toxin metabolic process
AM10699_22630	COG0668	transmembrane transport
AM10699_22680	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AM10699_22720	COG2204	response regulator
AM10699_22730	COG0784	Response regulator, receiver
AM10699_22730	COG2205	protein histidine kinase activity
AM10699_22890	COG2319	Wd-40 repeat
AM10699_22890	COG1672	PFAM Archaeal ATPase
AM10699_22900	COG0784	Response regulator, receiver
AM10699_22900	COG2205	protein histidine kinase activity
AM10699_22900	COG5002	protein histidine kinase activity
AM10699_22910	COG0121	glutamine amidotransferase
AM10699_22920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM10699_22930	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AM10699_22940	COG0443	Heat shock 70 kDa protein
AM10699_22950	COG0484	heat shock protein binding
AM10699_22980	COG3046	protein related to deoxyribodipyrimidine photolyase
AM10699_23010	COG3266	domain, Protein
AM10699_23010	COG0515	serine threonine protein kinase
AM10699_23030	COG0515	serine threonine protein kinase
AM10699_23050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AM10699_23070	COG5002	protein histidine kinase activity
AM10699_23070	COG0784	Response regulator, receiver
AM10699_23070	COG2205	protein histidine kinase activity
AM10699_23090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM10699_23150	COG1216	Glycosyl transferase, family 2
AM10699_23210	COG1132	(ABC) transporter
AM10699_23220	COG1215	transferase activity, transferring glycosyl groups
AM10699_23260	COG0438	transferase activity, transferring glycosyl groups
AM10699_23270	COG0438	transferase activity, transferring glycosyl groups
AM10699_23300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM10699_23320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AM10699_23370	COG0316	Belongs to the HesB IscA family
AM10699_23380	COG0662	Cupin 2, conserved barrel domain protein
AM10699_23380	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AM10699_23420	COG2385	sporulation resulting in formation of a cellular spore
AM10699_23430	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AM10699_23450	COG1131	(ABC) transporter
AM10699_23470	COG0473	3-isopropylmalate dehydrogenase activity
AM10699_23490	COG0515	serine threonine protein kinase
AM10699_23490	COG3266	domain, Protein
AM10699_23510	COG1494	fructose-1,6-bisphosphatase
AM10699_23520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM10699_23530	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM10699_23550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM10699_23570	COG0367	asparagine synthase
AM10699_23590	COG4106	trans-aconitate 2-methyltransferase activity
AM10699_23690	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM10699_23700	COG0138	bifunctional purine biosynthesis protein purh
AM10699_23710	COG2124	cytochrome p450
AM10699_23740	COG0515	serine threonine protein kinase
AM10699_23750	COG1801	Protein of unknown function DUF72
AM10699_23760	COG0488	(ABC) transporter
AM10699_23780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM10699_23790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM10699_23810	COG0107	imidazoleglycerol-phosphate synthase activity
AM10699_23850	COG3394	polysaccharide catabolic process
AM10699_23870	COG1032	radical SAM domain protein
AM10699_23890	COG0523	cobalamin synthesis protein
AM10699_24100	COG1073	alpha beta
AM10699_24360	COG0739	heme binding
AM10699_24510	COG4251	negative regulation of phosphorylation
AM10699_24530	COG0784	Response regulator, receiver
AM10699_24540	COG4251	negative regulation of phosphorylation
AM10699_24550	COG1846	Transcriptional regulator
AM10699_24560	COG0697	spore germination
AM10699_24580	COG1950	PFAM Membrane protein of
AM10699_24590	COG0435	Glutathione S-transferase
AM10699_24610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AM10699_24620	COG0776	regulation of translation
AM10699_24740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM10699_24750	COG1185	polyribonucleotide nucleotidyltransferase activity
AM10699_24760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM10699_24780	COG4251	negative regulation of phosphorylation
AM10699_24790	COG0326	Molecular chaperone. Has ATPase activity
AM10699_24820	COG0431	NADPH-dependent FMN reductase
AM10699_24850	COG0515	serine threonine protein kinase
AM10699_24850	COG3266	domain, Protein
AM10699_24870	COG1160	GTP binding
AM10699_24910	COG0483	inositol monophosphate 1-phosphatase activity
AM10699_24920	COG4178	(ABC) transporter
AM10699_25000	COG1733	regulation of RNA biosynthetic process
AM10699_25020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM10699_25020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AM10699_25040	COG2988	succinylglutamate desuccinylase activity
AM10699_25050	COG3706	GGDEF domain
AM10699_25110	COG2319	Wd-40 repeat
AM10699_25110	COG3903	Transcriptional regulator
AM10699_25190	COG0004	ammonium transporteR
AM10699_25230	COG1662	PFAM IS1 transposase
AM10699_25270	COG0784	Response regulator, receiver
AM10699_25270	COG5002	protein histidine kinase activity
AM10699_25340	COG0716	FMN binding
AM10699_25350	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AM10699_25360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM10699_25370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM10699_25380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM10699_25410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM10699_25440	COG2133	pyrroloquinoline quinone binding
AM10699_25450	COG2319	Wd-40 repeat
AM10699_25450	COG3903	Transcriptional regulator
AM10699_25480	COG2165	general secretion pathway protein
AM10699_25560	COG1271	oxidase subunit
AM10699_25630	COG1131	(ABC) transporter
AM10699_25660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AM10699_25720	COG0438	transferase activity, transferring glycosyl groups
AM10699_25740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_25760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM10699_25780	COG0405	Gamma-glutamyltransferase
AM10699_25830	COG0076	glutamate decarboxylase activity
AM10699_25890	COG4191	Histidine kinase
AM10699_25920	COG2205	protein histidine kinase activity
AM10699_25920	COG0784	Response regulator, receiver
AM10699_25930	COG2319	Wd-40 repeat
AM10699_25930	COG3903	Transcriptional regulator
AM10699_25970	COG0644	oxidoreductase
AM10699_26000	COG0604	alcohol dehydrogenase
AM10699_26030	COG2197	response regulator
AM10699_26070	COG2909	trisaccharide binding
AM10699_26230	COG0135	phosphoribosylanthranilate isomerase activity
AM10699_26260	COG4977	sequence-specific DNA binding
AM10699_26390	COG0702	epimerase
AM10699_26400	COG0582	viral genome integration into host DNA
AM10699_26460	COG0534	Mate efflux family protein
AM10699_26470	COG0783	Belongs to the Dps family
AM10699_26510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM10699_26540	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_26610	COG0475	glutathione-regulated potassium exporter activity
AM10699_26640	COG4584	PFAM Integrase catalytic
AM10699_26770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_26790	COG0776	regulation of translation
AM10699_26840	COG4227	nucleotidyltransferase activity
AM10699_26870	COG4974	Belongs to the 'phage' integrase family
AM10699_26990	COG3063	Type IV pilus biogenesis stability protein PilW
AM10699_27010	COG5001	Diguanylate cyclase
AM10699_27010	COG2203	Gaf domain
AM10699_27010	COG3706	GGDEF domain
AM10699_27010	COG4251	negative regulation of phosphorylation
AM10699_27080	COG1252	NADH dehydrogenase
AM10699_27090	COG4221	oxidoreductase activity
AM10699_27140	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AM10699_27210	COG2319	Wd-40 repeat
AM10699_27210	COG3903	Transcriptional regulator
AM10699_27220	COG2319	Wd-40 repeat
AM10699_27220	COG3903	Transcriptional regulator
AM10699_27280	COG1917	Cupin 2, conserved barrel domain protein
AM10699_27280	COG4977	sequence-specific DNA binding
AM10699_27310	COG4584	PFAM Integrase catalytic
AM10699_27320	COG1484	DNA-dependent DNA replication
AM10699_27340	COG3328	transposase activity
AM10699_27510	COG0698	ribose 5-phosphate isomerase
AM10699_27570	COG2165	general secretion pathway protein
AM10699_27700	COG2124	cytochrome p450
AM10699_27700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM10699_27720	COG1309	transcriptional regulator
AM10699_27730	COG4585	Histidine kinase
AM10699_27800	COG0515	serine threonine protein kinase
AM10699_27850	COG0640	Transcriptional regulator
AM10699_27860	COG0784	Response regulator, receiver
AM10699_27860	COG2198	Histidine kinase
AM10699_27860	COG2205	protein histidine kinase activity
AM10699_27890	COG2197	response regulator
AM10699_27920	COG2197	response regulator
AM10699_27930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM10699_27930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM10699_27950	COG1917	Cupin 2, conserved barrel domain protein
AM10699_27950	COG4977	sequence-specific DNA binding
AM10699_27960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM10699_27970	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AM10699_27980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM10699_27990	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM10699_28050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM10699_28070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM10699_28080	COG0745	RESPONSE REGULATOR receiver
AM10699_28090	COG2205	protein histidine kinase activity
AM10699_28090	COG4999	Histidine kinase
AM10699_28090	COG3850	Histidine kinase
AM10699_28090	COG3437	response regulator, receiver
AM10699_28100	COG0589	response to stress
AM10699_28110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM10699_28120	COG0589	response to stress
AM10699_28210	COG0697	spore germination
AM10699_28220	COG0189	ligase activity
AM10699_28270	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AM10699_28310	COG0493	'glutamate synthase
AM10699_28330	COG0784	Response regulator, receiver
AM10699_28330	COG2198	Histidine kinase
AM10699_28330	COG5002	protein histidine kinase activity
AM10699_28340	COG0784	Response regulator, receiver
AM10699_28340	COG2205	protein histidine kinase activity
AM10699_28370	COG0306	phosphate transporter
AM10699_28380	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_28390	COG0515	serine threonine protein kinase
AM10699_28390	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_28400	COG0067	glutamate synthase
AM10699_28400	COG0069	glutamate synthase activity
AM10699_28400	COG0070	glutamate synthase
AM10699_28450	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AM10699_28470	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_28480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM10699_28490	COG5002	protein histidine kinase activity
AM10699_28500	COG3659	wide pore channel activity
AM10699_28510	COG0588	phosphoglycerate mutase activity
AM10699_28530	COG0667	Aldo Keto reductase
AM10699_28560	COG1132	(ABC) transporter
AM10699_28580	COG1819	glycosyl
AM10699_28620	COG0745	RESPONSE REGULATOR receiver
AM10699_28630	COG1254	Belongs to the acylphosphatase family
AM10699_28640	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM10699_29050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM10699_29050	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AM10699_29120	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AM10699_29130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AM10699_29210	COG2233	PERMEase
AM10699_29220	COG2233	PERMEase
AM10699_29230	COG0697	spore germination
AM10699_29240	COG0616	signal peptide processing
AM10699_29480	COG0616	signal peptide processing
AM10699_29490	COG0697	spore germination
AM10699_29500	COG2233	PERMEase
AM10699_29570	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AM10699_29620	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AM10699_29620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AM10699_29640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM10699_29660	COG2197	response regulator
AM10699_29690	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AM10699_29700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM10699_29720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM10699_29760	COG3659	wide pore channel activity
AM10699_29780	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_29800	COG0802	atpase or kinase
AM10699_29820	COG2203	Gaf domain
AM10699_29820	COG0840	transmembrane signaling receptor activity
AM10699_29830	COG0702	epimerase
AM10699_29970	COG3328	transposase activity
AM10699_30000	COG1217	gtp-binding protein TYPA
AM10699_30010	COG0784	Response regulator, receiver
AM10699_30010	COG2205	protein histidine kinase activity
AM10699_30020	COG2203	Gaf domain
AM10699_30020	COG3706	GGDEF domain
AM10699_30020	COG4251	negative regulation of phosphorylation
AM10699_30020	COG5001	Diguanylate cyclase
AM10699_30030	COG0432	Pfam Uncharacterised protein family UPF0047
AM10699_30040	COG1840	ABC-type Fe3 transport system, periplasmic component
AM10699_30060	COG3264	Mechanosensitive ion channel
AM10699_30060	COG1196	nuclear chromosome segregation
AM10699_30090	COG0598	Magnesium transport protein CorA
AM10699_30130	COG0705	Rhomboid family
AM10699_30130	COG0457	Tetratricopeptide repeat
AM10699_30150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM10699_30260	COG3328	transposase activity
AM10699_30320	COG3536	Protein conserved in bacteria
AM10699_30330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM10699_30340	COG0315	cyclic pyranopterin monophosphate synthase activity
AM10699_30390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM10699_30410	COG1595	DNA-templated transcription, initiation
AM10699_30460	COG5433	transposase activity
AM10699_30490	COG0513	Belongs to the DEAD box helicase family
AM10699_30500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_30510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_30520	COG1260	myo-inositol-1-phosphate synthase
AM10699_30540	COG1131	(ABC) transporter
AM10699_30560	COG0837	glucose binding
AM10699_30580	COG0366	Alpha amylase catalytic
AM10699_30630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM10699_30650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AM10699_30700	COG0436	Aminotransferase
AM10699_30710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM10699_30750	COG4638	Rieske (2fe-2S)
AM10699_30770	COG0025	NhaP-type Na H and K H
AM10699_30810	COG3903	Transcriptional regulator
AM10699_30810	COG2319	Wd-40 repeat
AM10699_30830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM10699_30840	COG0848	biopolymer transport protein
AM10699_30860	COG0811	peptide transport
AM10699_30870	COG3903	Transcriptional regulator
AM10699_30870	COG2319	Wd-40 repeat
AM10699_30890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM10699_30900	COG0581	inorganic phosphate transmembrane transporter activity
AM10699_30910	COG0573	inorganic phosphate transmembrane transporter activity
AM10699_30920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM10699_30950	COG1943	Transposase
AM10699_30970	COG1366	Belongs to the anti-sigma-factor antagonist family
AM10699_31020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM10699_31050	COG3608	succinylglutamate desuccinylase aspartoacylase
AM10699_31050	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AM10699_31110	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AM10699_31190	COG1222	aaa ATPase
AM10699_31230	COG2197	response regulator
AM10699_31240	COG4191	Histidine kinase
AM10699_31370	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AM10699_31380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM10699_31390	COG2204	response regulator
AM10699_31400	COG0784	Response regulator, receiver
AM10699_31410	COG4251	negative regulation of phosphorylation
AM10699_31460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM10699_31460	COG0072	phenylalanine-tRNA ligase activity
AM10699_31480	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM10699_31520	COG1515	deoxyribonuclease V activity
AM10699_31590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM10699_31630	COG0672	)-iron permease
AM10699_31720	COG0175	sulfate reduction
AM10699_31800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM10699_31830	COG0534	Mate efflux family protein
AM10699_31860	COG2066	Belongs to the glutaminase family
AM10699_31910	COG0110	maltose O-acetyltransferase activity
AM10699_31920	COG0438	transferase activity, transferring glycosyl groups
AM10699_31960	COG0438	transferase activity, transferring glycosyl groups
AM10699_32020	COG1132	(ABC) transporter
AM10699_32030	COG0297	glycogen (starch) synthase activity
AM10699_32100	COG0745	RESPONSE REGULATOR receiver
AM10699_32110	COG5002	protein histidine kinase activity
AM10699_32140	COG1960	acyl-CoA dehydrogenase activity
AM10699_32150	COG0542	response to heat
AM10699_32170	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AM10699_32190	COG0529	Catalyzes the synthesis of activated sulfate
AM10699_32210	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AM10699_32230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AM10699_32250	COG0019	diaminopimelate decarboxylase activity
AM10699_32260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AM10699_32270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM10699_32300	COG1459	type II secretion system
AM10699_32320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM10699_32330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AM10699_32340	COG0443	Heat shock 70 kDa protein
AM10699_32350	COG0484	heat shock protein binding
AM10699_32370	COG1162	GTPase activity
AM10699_32410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM10699_32420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AM10699_32480	COG1882	Formate acetyltransferase
AM10699_32490	COG0574	Belongs to the PEP-utilizing enzyme family
AM10699_32490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM10699_32500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AM10699_32510	COG1454	alcohol dehydrogenase
AM10699_32510	COG1012	belongs to the aldehyde dehydrogenase family
AM10699_32520	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AM10699_32540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM10699_32580	COG0723	plastoquinol--plastocyanin reductase activity
AM10699_32600	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM10699_32610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM10699_32710	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AM10699_32720	COG5398	heme oxygenase
AM10699_32730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM10699_32750	COG0784	Response regulator, receiver
AM10699_32750	COG2198	Histidine kinase
AM10699_32750	COG2205	protein histidine kinase activity
AM10699_32780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM10699_32870	COG2346	COG2346, Truncated hemoglobins
AM10699_32900	COG3335	DDE superfamily endonuclease
AM10699_33010	COG1484	DNA-dependent DNA replication
AM10699_33020	COG4584	PFAM Integrase catalytic
AM10699_33150	COG2197	response regulator
AM10699_33160	COG4585	Histidine kinase
AM10699_33170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM10699_33230	COG0657	acetylesterase activity
AM10699_33240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM10699_33250	COG1191	sigma factor activity
AM10699_33280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM10699_33310	COG4372	Transposase
AM10699_33320	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AM10699_33320	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AM10699_33450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AM10699_33510	COG1192	Involved in chromosome partitioning
AM10699_33520	COG0583	DNA-binding transcription factor activity
AM10699_33550	COG0501	Belongs to the peptidase M48B family
AM10699_33570	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AM10699_33590	COG4251	negative regulation of phosphorylation
AM10699_33590	COG3706	GGDEF domain
AM10699_33590	COG2203	Gaf domain
AM10699_33590	COG5001	Diguanylate cyclase
AM10699_33620	COG0724	RNA recognition motif
AM10699_33680	COG0110	maltose O-acetyltransferase activity
AM10699_33690	COG0438	transferase activity, transferring glycosyl groups
AM10699_33720	COG5001	Diguanylate cyclase
AM10699_33730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM10699_33740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM10699_33760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AM10699_33770	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AM10699_33790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AM10699_33810	COG0483	inositol monophosphate 1-phosphatase activity
AM10699_33830	COG0471	metal ion transport
AM10699_33830	COG3273	potassium ion transport
AM10699_33840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM10699_33850	COG0798	PFAM Bile acid sodium symporter
AM10699_33860	COG0789	Transcriptional regulator
AM10699_33880	COG0751	glycine-tRNA ligase activity
AM10699_33890	COG0612	Peptidase, M16
AM10699_33910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM10699_33920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM10699_33930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM10699_33940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM10699_33960	COG2124	cytochrome p450
AM10699_33980	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM10699_33980	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM10699_33990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AM10699_34050	COG0408	coproporphyrinogen oxidase activity
AM10699_34070	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AM10699_34090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AM10699_34100	COG0501	Belongs to the peptidase M48B family
AM10699_34140	COG0739	heme binding
AM10699_34150	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AM10699_34150	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AM10699_34160	COG1496	oxidoreductase activity
AM10699_34210	COG0583	DNA-binding transcription factor activity
AM10699_34220	COG1741	Belongs to the pirin family
AM10699_34240	COG2205	protein histidine kinase activity
AM10699_34240	COG0784	Response regulator, receiver
AM10699_34250	COG0589	response to stress
AM10699_34260	COG0126	phosphoglycerate kinase activity
AM10699_34320	COG0124	histidyl-tRNA synthetase
AM10699_34360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM10699_34370	COG1136	(ABC) transporter
AM10699_34370	COG0577	efflux transmembrane transporter activity
AM10699_34380	COG1136	(ABC) transporter
AM10699_34400	COG0416	fatty acid biosynthetic process
AM10699_34410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM10699_34420	COG0697	spore germination
AM10699_34430	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM10699_34440	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AM10699_34450	COG1125	glycine betaine transport
AM10699_34450	COG0517	IMP dehydrogenase activity
AM10699_34480	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AM10699_34500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM10699_34530	COG0484	heat shock protein binding
AM10699_34540	COG1994	Peptidase M50
AM10699_34560	COG0390	transport system, permease component
AM10699_34570	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AM10699_34660	COG1662	PFAM IS1 transposase
AM10699_34680	COG1487	ribonuclease activity
AM10699_34760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM10699_34770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM10699_34780	COG0022	dehydrogenase e1 component
AM10699_34780	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM10699_34810	COG2226	methyltransferase
AM10699_34830	COG0515	serine threonine protein kinase
AM10699_34870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM10699_34910	COG3328	transposase activity
AM10699_34950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM10699_34960	COG5001	Diguanylate cyclase
AM10699_34960	COG2203	Gaf domain
AM10699_34960	COG4251	negative regulation of phosphorylation
AM10699_34960	COG3706	GGDEF domain
AM10699_34980	COG2319	Wd-40 repeat
AM10699_34980	COG1672	PFAM Archaeal ATPase
AM10699_34980	COG2319	Wd-40 repeat
AM10699_34980	COG1672	PFAM Archaeal ATPase
AM10699_35010	COG0318	PFAM AMP-dependent synthetase and ligase
AM10699_35060	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_35060	COG4221	oxidoreductase activity
AM10699_35060	COG3321	synthase
AM10699_35060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM10699_35070	COG0156	8-amino-7-oxononanoate synthase activity
AM10699_35090	COG4221	oxidoreductase activity
AM10699_35210	COG1662	PFAM IS1 transposase
AM10699_35230	COG0587	DNA-directed DNA polymerase activity
AM10699_35250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AM10699_35260	COG0814	amino acid
AM10699_35380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM10699_35460	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AM10699_35490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM10699_35500	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM10699_35530	COG2363	Small membrane protein
AM10699_35550	COG1361	Conserved repeat domain
AM10699_35590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM10699_35610	COG1515	deoxyribonuclease V activity
AM10699_35670	COG1615	UPF0182 protein
AM10699_35690	COG0646	methionine synthase
AM10699_35690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM10699_35740	COG0431	NADPH-dependent FMN reductase
AM10699_35770	COG0438	transferase activity, transferring glycosyl groups
AM10699_35810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM10699_35820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM10699_35840	COG1122	ATPase activity
AM10699_35850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM10699_35900	COG0753	catalase activity
AM10699_35930	COG1309	transcriptional regulator
AM10699_35950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM10699_35970	COG2124	cytochrome p450
AM10699_36000	COG0745	RESPONSE REGULATOR receiver
AM10699_36020	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AM10699_36030	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AM10699_36030	COG1672	PFAM Archaeal ATPase
AM10699_36070	COG1233	COG1233 Phytoene dehydrogenase and related
AM10699_36120	COG0612	Peptidase, M16
AM10699_36140	COG3011	Protein conserved in bacteria
AM10699_36180	COG0768	penicillin binding
AM10699_36200	COG0275	rRNA processing
AM10699_36210	COG5398	heme oxygenase
AM10699_36240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AM10699_36260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AM10699_36270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM10699_36340	COG3659	wide pore channel activity
AM10699_36350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AM10699_36360	COG0830	nickel cation binding
AM10699_36430	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AM10699_36440	COG0175	sulfate reduction
AM10699_36510	COG2226	methyltransferase
AM10699_36570	COG0356	it plays a direct role in the translocation of protons across the membrane
AM10699_36590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM10699_36600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AM10699_36610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AM10699_36620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AM10699_36630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AM10699_36640	COG0473	3-isopropylmalate dehydrogenase activity
AM10699_36650	COG4636	protein conserved in cyanobacteria
AM10699_36700	COG0066	3-isopropylmalate dehydratase activity
AM10699_36720	COG0784	Response regulator, receiver
AM10699_36750	COG0840	transmembrane signaling receptor activity
AM10699_36750	COG2203	Gaf domain
AM10699_36760	COG0784	Response regulator, receiver
AM10699_36760	COG2198	Histidine kinase
AM10699_36760	COG0643	Histidine kinase
AM10699_36790	COG0004	ammonium transporteR
AM10699_36810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AM10699_36820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM10699_36850	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AM10699_36860	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AM10699_36890	COG0779	Required for maturation of 30S ribosomal subunits
AM10699_36900	COG0195	Participates in both transcription termination and antitermination
AM10699_36910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AM10699_36980	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM10699_37010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM10699_37020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM10699_37060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM10699_37070	COG0469	pyruvate kinase activity
AM10699_37080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM10699_37110	COG2217	Heavy metal translocating P-type atpase
AM10699_37170	COG2831	hemolysin activation secretion protein
AM10699_37180	COG2205	protein histidine kinase activity
AM10699_37220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM10699_37280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM10699_37310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM10699_37320	COG1136	(ABC) transporter
AM10699_37380	COG0564	pseudouridine synthase activity
AM10699_37430	COG1136	(ABC) transporter
AM10699_37480	COG0457	Tetratricopeptide repeat
AM10699_37480	COG0463	Glycosyl transferase, family 2
AM10699_37490	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AM10699_37500	COG4251	negative regulation of phosphorylation
AM10699_37530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AM10699_37580	COG1045	serine acetyltransferase
AM10699_37620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM10699_37630	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AM10699_37650	COG0517	IMP dehydrogenase activity
AM10699_37650	COG0617	tRNA 3'-terminal CCA addition
AM10699_37650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AM10699_37660	COG4597	amino acid ABC transporter
AM10699_37670	COG0765	amino acid transport
AM10699_37680	COG1126	abc transporter atp-binding protein
AM10699_37700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM10699_37740	COG0438	transferase activity, transferring glycosyl groups
AM10699_37750	COG0438	transferase activity, transferring glycosyl groups
AM10699_37850	COG0495	leucyl-tRNA aminoacylation
AM10699_37870	COG3657	addiction module killer protein
AM10699_37880	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM10699_37970	COG0583	DNA-binding transcription factor activity
AM10699_38000	COG1672	PFAM Archaeal ATPase
AM10699_38000	COG2319	Wd-40 repeat
AM10699_38010	COG5001	Diguanylate cyclase
AM10699_38010	COG4251	negative regulation of phosphorylation
AM10699_38010	COG2203	Gaf domain
AM10699_38010	COG3706	GGDEF domain
AM10699_38030	COG0424	maF-like protein
AM10699_38070	COG0024	Methionine aminopeptidase
AM10699_38090	COG1968	undecaprenyl-diphosphatase activity
AM10699_38120	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM10699_38130	COG1799	cell septum assembly
AM10699_38140	COG0277	FAD linked oxidase domain protein
AM10699_38190	COG3239	Fatty acid desaturase
AM10699_38210	COG1054	Belongs to the UPF0176 family
AM10699_38230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM10699_38240	COG0456	acetyltransferase
AM10699_38250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM10699_38300	COG0653	protein targeting
AM10699_38320	COG2095	MarC family integral membrane protein
AM10699_38350	COG1446	asparaginase
AM10699_38390	COG2226	methyltransferase
AM10699_38400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AM10699_38460	COG3541	Predicted nucleotidyltransferase
AM10699_38490	COG0840	transmembrane signaling receptor activity
AM10699_38530	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AM10699_38550	COG1575	Belongs to the MenA family. Type 1 subfamily
AM10699_38560	COG0484	heat shock protein binding
AM10699_38570	COG0702	epimerase
AM10699_38580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM10699_38600	COG0322	excinuclease ABC activity
AM10699_38620	COG0297	glycogen (starch) synthase activity
AM10699_38640	COG1309	transcriptional regulator
AM10699_38670	COG1649	PFAM Uncharacterised BCR, COG1649
AM10699_38700	COG0735	belongs to the Fur family
AM10699_38770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AM10699_38790	COG1420	regulation of RNA biosynthetic process
AM10699_38850	COG0501	Belongs to the peptidase M48B family
AM10699_38880	COG0776	regulation of translation
AM10699_38890	COG0575	Belongs to the CDS family
AM10699_38910	COG0745	RESPONSE REGULATOR receiver
AM10699_38920	COG2172	sigma factor antagonist activity
AM10699_38930	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AM10699_38940	COG1051	belongs to the nudix hydrolase family
AM10699_38950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM10699_38960	COG0456	acetyltransferase
AM10699_38980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM10699_39080	COG1331	Highly conserved protein containing a thioredoxin domain
AM10699_39120	COG1671	Belongs to the UPF0178 family
AM10699_39160	COG0625	glutathione transferase activity
AM10699_39190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM10699_39190	COG2205	protein histidine kinase activity
AM10699_39200	COG2205	protein histidine kinase activity
AM10699_39200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM10699_39210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AM10699_39290	COG0523	cobalamin synthesis protein
AM10699_39360	COG5635	Nacht domain
AM10699_39360	COG2319	Wd-40 repeat
AM10699_39380	COG2319	Wd-40 repeat
AM10699_39380	COG5635	Nacht domain
AM10699_39410	COG1252	NADH dehydrogenase
AM10699_39540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM10699_39550	COG0719	Fe-S assembly protein
AM10699_39560	COG0396	ATPase activity
AM10699_39570	COG0719	Fe-S assembly protein
AM10699_39600	COG1309	transcriptional regulator
AM10699_39610	COG0625	glutathione transferase activity
AM10699_39710	COG4221	oxidoreductase activity
AM10699_39720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM10699_39730	COG1376	ErfK ybiS ycfS ynhG family protein
AM10699_39740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AM10699_39750	COG0254	rRNA binding
AM10699_39760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM10699_39770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AM10699_39780	COG0101	tRNA pseudouridine synthase activity
AM10699_39790	COG0203	ribosomal protein L17
AM10699_39800	COG0202	RNA polymerase activity
AM10699_39810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AM10699_39820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AM10699_39830	COG0646	methionine synthase
AM10699_39830	COG1410	methionine synthase
AM10699_39870	COG0584	glycerophosphoryl diester phosphodiesterase
AM10699_39890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM10699_39900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM10699_39920	COG2827	Endonuclease containing a URI domain
AM10699_39940	COG3012	SEC-C Motif Domain Protein
AM10699_40000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM10699_40010	COG2264	protein methyltransferase activity
AM10699_40070	COG2911	Protein conserved in bacteria
AM10699_40070	COG3266	domain, Protein
AM10699_40070	COG1361	Conserved repeat domain
AM10699_40080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM10699_40090	COG4956	integral membrane protein (PIN domain superfamily)
AM10699_40260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_40290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_40300	COG1597	lipid kinase activity
AM10699_40300	COG1803	Methylglyoxal synthase
AM10699_40390	COG2207	Transcriptional regulator
AM10699_40440	COG0667	Aldo Keto reductase
AM10699_40460	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AM10699_40470	COG1073	alpha beta
AM10699_40520	COG1309	transcriptional regulator
AM10699_40530	COG1454	alcohol dehydrogenase
AM10699_40540	COG1012	belongs to the aldehyde dehydrogenase family
AM10699_40630	COG0159	tryptophan synthase activity
AM10699_40660	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM10699_40680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM10699_40770	COG0606	chelatase, subunit chli
AM10699_40780	COG3063	Type IV pilus biogenesis stability protein PilW
AM10699_40790	COG4172	Belongs to the ABC transporter superfamily
AM10699_40800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_40820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM10699_40830	COG2045	Belongs to the ComB family
AM10699_40860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_40870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AM10699_40880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM10699_40890	COG0339	signal peptide processing
AM10699_40900	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_40900	COG0515	serine threonine protein kinase
AM10699_40910	COG0840	transmembrane signaling receptor activity
AM10699_40910	COG2203	Gaf domain
AM10699_40920	COG2205	protein histidine kinase activity
AM10699_40920	COG0784	Response regulator, receiver
AM10699_40940	COG0303	'Molybdopterin
AM10699_40960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM10699_40960	COG0426	domain, Protein
AM10699_40980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM10699_40980	COG0426	domain, Protein
AM10699_41010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM10699_41060	COG0114	fumarate hydratase activity
AM10699_41110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM10699_41120	COG3264	Mechanosensitive ion channel
AM10699_41120	COG1196	nuclear chromosome segregation
AM10699_41150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM10699_41160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM10699_41200	COG1473	amidohydrolase
AM10699_41260	COG2308	Evidence 4 Homologs of previously reported genes of
AM10699_41280	COG5001	Diguanylate cyclase
AM10699_41280	COG5002	protein histidine kinase activity
AM10699_41290	COG0709	Synthesizes selenophosphate from selenide and ATP
AM10699_41320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM10699_41330	COG3903	Transcriptional regulator
AM10699_41330	COG2319	Wd-40 repeat
AM10699_41340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM10699_41350	COG0546	phosphoglycolate phosphatase activity
AM10699_41380	COG0512	Glutamine amidotransferase of anthranilate synthase
AM10699_41390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AM10699_41400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AM10699_41420	COG0047	phosphoribosylformylglycinamidine synthase activity
AM10699_41430	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM10699_41440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM10699_41460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM10699_41460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM10699_41490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AM10699_41520	COG1278	Cold shock
AM10699_41530	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AM10699_41540	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AM10699_41560	COG0489	protein tyrosine kinase activity
AM10699_41570	COG0772	Belongs to the SEDS family
AM10699_41600	COG0539	negative regulation of cytoplasmic translation
AM10699_41610	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AM10699_41670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM10699_41720	COG2205	protein histidine kinase activity
AM10699_41850	COG0745	RESPONSE REGULATOR receiver
AM10699_41920	COG0762	integral membrane protein
AM10699_41930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AM10699_41950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM10699_41980	COG0174	glutamine synthetase
AM10699_42000	COG5002	protein histidine kinase activity
AM10699_42000	COG0784	Response regulator, receiver
AM10699_42050	COG2239	Acts as a magnesium transporter
AM10699_42060	COG0191	fructose-bisphosphate aldolase activity
AM10699_42070	COG0739	heme binding
AM10699_42080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM10699_42090	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AM10699_42110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AM10699_42170	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_42180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AM10699_42190	COG1063	alcohol dehydrogenase
AM10699_42210	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AM10699_42220	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AM10699_42240	COG0509	glycine decarboxylation via glycine cleavage system
AM10699_42250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AM10699_42300	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AM10699_42310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM10699_42370	COG1733	regulation of RNA biosynthetic process
AM10699_42410	COG2198	Histidine kinase
AM10699_42410	COG0784	Response regulator, receiver
AM10699_42410	COG2205	protein histidine kinase activity
AM10699_42490	COG4585	Histidine kinase
AM10699_42500	COG2197	response regulator
AM10699_42530	COG2226	methyltransferase
AM10699_42570	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AM10699_42630	COG0515	serine threonine protein kinase
AM10699_42630	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_42690	COG0515	serine threonine protein kinase
AM10699_42690	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_42700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM10699_42770	COG1126	abc transporter atp-binding protein
AM10699_42800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_42810	COG1136	(ABC) transporter
AM10699_42860	COG0625	glutathione transferase activity
AM10699_42870	COG1733	regulation of RNA biosynthetic process
AM10699_42950	COG3328	transposase activity
AM10699_42970	COG0604	alcohol dehydrogenase
AM10699_43000	COG1024	Enoyl-CoA hydratase
AM10699_43000	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM10699_43010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM10699_43020	COG4221	oxidoreductase activity
AM10699_43070	COG2203	Gaf domain
AM10699_43070	COG3706	GGDEF domain
AM10699_43070	COG4251	negative regulation of phosphorylation
AM10699_43070	COG5001	Diguanylate cyclase
AM10699_43080	COG1049	propionate catabolic process, 2-methylcitrate cycle
AM10699_43140	COG0135	phosphoribosylanthranilate isomerase activity
AM10699_43160	COG0167	dihydroorotate dehydrogenase activity
AM10699_43190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM10699_43210	COG0574	Belongs to the PEP-utilizing enzyme family
AM10699_43210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM10699_43220	COG0589	response to stress
AM10699_43250	COG1305	Transglutaminase-like
AM10699_43300	COG3854	ATPases associated with a variety of cellular activities
AM10699_43320	COG5002	protein histidine kinase activity
AM10699_43340	COG2072	flavoprotein involved in K transport
AM10699_43350	COG1166	arginine decarboxylase activity
AM10699_43370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_43390	COG0067	glutamate synthase
AM10699_43390	COG0069	glutamate synthase activity
AM10699_43390	COG0070	glutamate synthase
AM10699_43430	COG0121	glutamine amidotransferase
AM10699_43440	COG1404	Belongs to the peptidase S8 family
AM10699_43470	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM10699_43480	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AM10699_43540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM10699_43550	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM10699_43570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM10699_43610	COG1032	radical SAM domain protein
AM10699_43650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM10699_43660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM10699_43690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM10699_43700	COG0513	Belongs to the DEAD box helicase family
AM10699_43710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM10699_43720	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AM10699_43730	COG1530	ribonuclease E activity
AM10699_43740	COG0412	Dienelactone hydrolase
AM10699_43750	COG1725	Transcriptional regulator
AM10699_43760	COG2304	oxidoreductase activity
AM10699_43790	COG0612	Peptidase, M16
AM10699_43820	COG0571	ribonuclease III activity
AM10699_43830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AM10699_43840	COG0484	heat shock protein binding
AM10699_43850	COG0037	tRNA processing
AM10699_43860	COG0745	RESPONSE REGULATOR receiver
AM10699_43880	COG1011	Hydrolase
AM10699_43910	COG0784	Response regulator, receiver
AM10699_43920	COG4251	negative regulation of phosphorylation
AM10699_43930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM10699_43960	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AM10699_43980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AM10699_44000	COG0180	Tryptophanyl-tRNA synthetase
AM10699_44010	COG5002	protein histidine kinase activity
AM10699_44030	COG0285	dihydrofolate synthase activity
AM10699_44080	COG1132	(ABC) transporter
AM10699_44090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AM10699_44100	COG2010	Cytochrome c
AM10699_44140	COG1819	glycosyl
AM10699_44170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AM10699_44180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM10699_44230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM10699_44300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AM10699_44310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM10699_44360	COG0243	molybdopterin cofactor binding
AM10699_44470	COG4451	ribulose bisphosphate carboxylase, small
AM10699_44490	COG1850	ribulose-bisphosphate carboxylase activity
AM10699_44500	COG0454	-acetyltransferase
AM10699_44530	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AM10699_44580	COG0051	transcription antitermination factor activity, RNA binding
AM10699_44590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AM10699_44600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM10699_44610	COG0049	tRNA binding
AM10699_44620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AM10699_44630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AM10699_44640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AM10699_44650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM10699_44660	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AM10699_44700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AM10699_44720	COG0745	RESPONSE REGULATOR receiver
AM10699_44740	COG1333	cytochrome c biogenesis protein
AM10699_44760	COG0772	Belongs to the SEDS family
AM10699_44790	COG3659	wide pore channel activity
AM10699_44840	COG1136	(ABC) transporter
AM10699_44910	COG0659	secondary active sulfate transmembrane transporter activity
AM10699_44920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_44930	COG2217	Heavy metal translocating P-type atpase
AM10699_44970	COG2321	neutral zinc metallopeptidase
AM10699_45030	COG5001	Diguanylate cyclase
AM10699_45030	COG4251	negative regulation of phosphorylation
AM10699_45030	COG3706	GGDEF domain
AM10699_45030	COG2203	Gaf domain
AM10699_45070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM10699_45080	COG0217	transcriptional regulatory protein
AM10699_45100	COG2884	Cell division ATP-binding protein ftsE
AM10699_45110	COG2177	Part of the ABC transporter FtsEX involved in
AM10699_45150	COG0515	serine threonine protein kinase
AM10699_45150	COG2815	serine threonine protein kinase
AM10699_45220	COG1666	GTP binding
AM10699_45230	COG1012	belongs to the aldehyde dehydrogenase family
AM10699_45260	COG0516	GMP reductase activity
AM10699_45270	COG3118	belongs to the thioredoxin family
AM10699_45290	COG5002	protein histidine kinase activity
AM10699_45290	COG0784	Response regulator, receiver
AM10699_45290	COG2205	protein histidine kinase activity
AM10699_45330	COG0693	protein deglycase activity
AM10699_45350	COG0737	Belongs to the 5'-nucleotidase family
AM10699_45380	COG0436	Aminotransferase
AM10699_45410	COG0540	Belongs to the ATCase OTCase family
AM10699_45430	COG1122	ATPase activity
AM10699_45460	COG3594	Acyltransferase
AM10699_45480	COG2226	methyltransferase
AM10699_45500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AM10699_45510	COG0438	transferase activity, transferring glycosyl groups
AM10699_45530	COG2226	methyltransferase
AM10699_45580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM10699_45600	COG2244	polysaccharide biosynthetic process
AM10699_45610	COG0489	protein tyrosine kinase activity
AM10699_45610	COG3206	protein involved in exopolysaccharide biosynthesis
AM10699_45650	COG0438	transferase activity, transferring glycosyl groups
AM10699_45690	COG2850	peptidyl-arginine hydroxylation
AM10699_45700	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AM10699_45750	COG1473	amidohydrolase
AM10699_45800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM10699_45810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM10699_45840	COG0360	Binds together with S18 to 16S ribosomal RNA
AM10699_45850	COG3287	FIST C domain
AM10699_45850	COG2200	EAL domain
AM10699_45850	COG2199	diguanylate cyclase activity
AM10699_45890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AM10699_45900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM10699_45910	COG1546	Belongs to the CinA family
AM10699_45910	COG1058	Belongs to the CinA family
AM10699_45930	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AM10699_45940	COG0488	(ABC) transporter
AM10699_45960	COG0456	acetyltransferase
AM10699_45970	COG0542	response to heat
AM10699_46000	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM10699_46040	COG0037	tRNA processing
AM10699_46080	COG0352	thiamine-phosphate diphosphorylase activity
AM10699_46100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AM10699_46130	COG1858	cytochrome C peroxidase
AM10699_46140	COG5002	protein histidine kinase activity
AM10699_46140	COG0784	Response regulator, receiver
AM10699_46170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM10699_46170	COG4191	Histidine kinase
AM10699_46190	COG0434	BtpA family
AM10699_46200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM10699_46220	COG0494	nUDIX hydrolase
AM10699_46230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM10699_46270	COG3596	GTP binding
AM10699_46350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM10699_46360	COG0501	Belongs to the peptidase M48B family
AM10699_46430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AM10699_46450	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AM10699_46570	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AM10699_46580	COG1819	glycosyl
AM10699_46610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AM10699_46640	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AM10699_46660	COG0668	transmembrane transport
AM10699_46670	COG0017	Asparaginyl-tRNA synthetase
AM10699_46690	COG0297	glycogen (starch) synthase activity
AM10699_46700	COG0724	RNA recognition motif
AM10699_46740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM10699_46750	COG3977	Valine--pyruvate aminotransferase
AM10699_46800	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AM10699_46870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM10699_46880	COG1007	ATP synthesis coupled electron transport
AM10699_46900	COG0644	oxidoreductase
AM10699_46920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AM10699_46930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM10699_46950	COG0742	ribosomal rna small subunit methyltransferase
AM10699_47010	COG0443	Heat shock 70 kDa protein
AM10699_47040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM10699_47050	COG0460	homoserine dehydrogenase
AM10699_47100	COG0456	acetyltransferase
AM10699_47120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AM10699_47130	COG0616	signal peptide processing
AM10699_47150	COG2207	Transcriptional regulator
AM10699_47190	COG0702	epimerase
AM10699_47210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM10699_47230	COG0747	negative chemotaxis
AM10699_47250	COG0793	Belongs to the peptidase S41A family
AM10699_47270	COG1858	cytochrome C peroxidase
AM10699_47290	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM10699_47310	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AM10699_47420	COG1640	4-alpha-glucanotransferase
AM10699_47430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM10699_47470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_47480	COG0735	belongs to the Fur family
AM10699_47510	COG0572	uridine kinase
AM10699_47520	COG0058	SHG alpha-glucan phosphorylase activity
AM10699_47530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM10699_47550	COG2267	carboxylic ester hydrolase activity
AM10699_47560	COG0440	acetolactate synthase activity
AM10699_47590	COG0439	Biotin carboxylase
AM10699_47610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AM10699_47620	COG0542	response to heat
AM10699_47640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM10699_47660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_47690	COG0475	glutathione-regulated potassium exporter activity
AM10699_47710	COG0039	L-malate dehydrogenase activity
AM10699_47770	COG2267	carboxylic ester hydrolase activity
AM10699_47790	COG1024	Enoyl-CoA hydratase
AM10699_47790	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM10699_47800	COG0183	Belongs to the thiolase family
AM10699_47810	COG1960	acyl-CoA dehydrogenase activity
AM10699_47820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM10699_47820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AM10699_47870	COG2062	phosphohistidine phosphatase, SixA
AM10699_47880	COG0372	Belongs to the citrate synthase family
AM10699_47890	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AM10699_47900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_47940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM10699_47990	COG0537	adenosine 5'-monophosphoramidase activity
AM10699_48010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM10699_48020	COG0629	single-stranded DNA binding
AM10699_48030	COG0151	Belongs to the GarS family
AM10699_48090	COG1716	ATPase activity
AM10699_48090	COG1131	(ABC) transporter
AM10699_48090	COG0842	Transport permease protein
AM10699_48100	COG2815	serine threonine protein kinase
AM10699_48100	COG0515	serine threonine protein kinase
AM10699_48110	COG1253	flavin adenine dinucleotide binding
AM10699_48120	COG1178	ABC-type Fe3 transport system permease component
AM10699_48130	COG0445	tRNA wobble uridine modification
AM10699_48170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM10699_48180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM10699_48220	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM10699_48220	COG0517	IMP dehydrogenase activity
AM10699_48230	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AM10699_48240	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AM10699_48250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM10699_48450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM10699_48470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM10699_48500	COG2072	flavoprotein involved in K transport
AM10699_48560	COG2144	transferase activity, transferring acyl groups
AM10699_48580	COG0732	type I restriction modification DNA specificity domain
AM10699_48630	COG0438	transferase activity, transferring glycosyl groups
AM10699_48650	COG2197	response regulator
AM10699_48710	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_48750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM10699_48780	COG0625	glutathione transferase activity
AM10699_48830	COG0583	DNA-binding transcription factor activity
AM10699_48860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM10699_49040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AM10699_49050	COG1494	fructose-1,6-bisphosphatase
AM10699_49080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM10699_49080	COG0456	acetyltransferase
AM10699_49100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM10699_49120	COG3266	domain, Protein
AM10699_49120	COG0515	serine threonine protein kinase
AM10699_49130	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AM10699_49140	COG0156	8-amino-7-oxononanoate synthase activity
AM10699_49170	COG4172	Belongs to the ABC transporter superfamily
AM10699_49190	COG0728	peptidoglycan biosynthetic process
AM10699_49200	COG0728	peptidoglycan biosynthetic process
AM10699_49230	COG4221	oxidoreductase activity
AM10699_49240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM10699_49260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM10699_49310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM10699_49340	COG1127	ABC transporter
AM10699_49370	COG0442	prolyl-tRNA aminoacylation
AM10699_49410	COG0387	Pfam Sodium calcium exchanger
AM10699_49450	COG0740	serine-type endopeptidase activity
AM10699_49460	COG0740	serine-type endopeptidase activity
AM10699_49510	COG0456	acetyltransferase
AM10699_49510	COG1846	Transcriptional regulator
AM10699_49520	COG0564	pseudouridine synthase activity
AM10699_49530	COG0613	PHP domain protein
AM10699_49550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_49560	COG1489	DNA binding
AM10699_49580	COG0602	queuosine metabolic process
AM10699_49590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM10699_49610	COG1040	competence protein
AM10699_49620	COG0574	Belongs to the PEP-utilizing enzyme family
AM10699_49620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM10699_49640	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AM10699_49670	COG0739	heme binding
AM10699_49690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AM10699_49720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM10699_49730	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AM10699_49760	COG0714	Associated with various cellular activities
AM10699_49800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM10699_49810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AM10699_49820	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AM10699_49880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AM10699_49890	COG0631	protein serine/threonine phosphatase activity
AM10699_49900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM10699_49950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM10699_50000	COG1716	ATPase activity
AM10699_50000	COG5001	Diguanylate cyclase
AM10699_50020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM10699_50140	COG2176	DNA-directed DNA polymerase activity
AM10699_50190	COG5433	transposase activity
AM10699_50250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM10699_50260	COG0563	adenylate kinase activity
AM10699_50270	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AM10699_50290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM10699_50310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AM10699_50340	COG2154	pterin-4-alpha-carbinolamine dehydratase
AM10699_50350	COG0357	Ribosomal RNA small subunit methyltransferase G
AM10699_50360	COG3128	pkhd-type hydroxylase
AM10699_50380	COG0415	Belongs to the DNA photolyase family
AM10699_50410	COG3693	PFAM glycoside hydrolase, family 10
AM10699_50450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM10699_50480	COG0443	Heat shock 70 kDa protein
AM10699_50520	COG0351	phosphomethylpyrimidine kinase
AM10699_50630	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AM10699_50650	COG2885	chlorophyll binding
AM10699_50660	COG2885	chlorophyll binding
AM10699_50690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM10699_50710	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AM10699_50720	COG1716	ATPase activity
AM10699_50720	COG0842	Transport permease protein
AM10699_50720	COG1131	(ABC) transporter
AM10699_50730	COG0312	modulator of DNA gyrase
AM10699_50740	COG0312	modulator of DNA gyrase
AM10699_50750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM10699_50760	COG0438	transferase activity, transferring glycosyl groups
AM10699_50890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM10699_50960	COG3001	Fructosamine kinase
AM10699_51000	COG1619	proteins homologs of microcin C7 resistance protein MccF
AM10699_51030	COG3118	belongs to the thioredoxin family
AM10699_51040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM10699_51050	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM10699_51080	COG0714	Associated with various cellular activities
AM10699_51090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AM10699_51110	COG2205	protein histidine kinase activity
AM10699_51130	COG1672	PFAM Archaeal ATPase
AM10699_51130	COG2319	Wd-40 repeat
AM10699_51140	COG0515	serine threonine protein kinase
AM10699_51200	COG0587	DNA-directed DNA polymerase activity
AM10699_51210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM10699_51220	COG4245	von Willebrand factor, type A
AM10699_51270	COG0705	Rhomboid family
AM10699_51350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM10699_51360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM10699_51370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM10699_51400	COG0667	Aldo Keto reductase
AM10699_51440	COG0464	growth
AM10699_51460	COG2020	methyltransferase activity
AM10699_51520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM10699_51530	COG1695	Transcriptional regulator
AM10699_51610	COG0431	NADPH-dependent FMN reductase
AM10699_51630	COG0475	glutathione-regulated potassium exporter activity
AM10699_51630	COG0589	response to stress
AM10699_51640	COG1716	ATPase activity
AM10699_51660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM10699_51660	COG0140	phosphoribosyl-ATP diphosphatase activity
AM10699_51690	COG3118	belongs to the thioredoxin family
AM10699_51700	COG0358	DNA primase activity
AM10699_51740	COG1902	pentaerythritol trinitrate reductase activity
AM10699_51750	COG2010	Cytochrome c
AM10699_51770	COG1858	cytochrome C peroxidase
AM10699_51790	COG1566	PFAM secretion protein HlyD family protein
AM10699_51810	COG0577	efflux transmembrane transporter activity
AM10699_51810	COG1136	(ABC) transporter
AM10699_51870	COG1595	DNA-templated transcription, initiation
AM10699_51900	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM10699_52000	COG1181	Belongs to the D-alanine--D-alanine ligase family
AM10699_52010	COG1509	lysine 2,3-aminomutase activity
AM10699_52020	COG2720	vancomycin resistance protein
AM10699_52090	COG4115	mRNA cleavage
AM10699_52160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM10699_52170	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AM10699_52190	COG0525	valine-tRNA ligase activity
AM10699_52200	COG0724	RNA recognition motif
AM10699_52210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AM10699_52220	COG1047	Peptidyl-prolyl cis-trans
AM10699_52250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AM10699_52250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM10699_52260	COG0436	Aminotransferase
AM10699_52310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AM10699_52340	COG4447	cellulose binding
AM10699_52350	COG1773	rubredoxin
AM10699_52360	COG0012	GTP binding
AM10699_52370	COG1982	Orn Lys Arg decarboxylase major
AM10699_52400	COG0363	glucosamine-6-phosphate deaminase activity
AM10699_52410	COG1716	ATPase activity
AM10699_52420	COG0515	serine threonine protein kinase
AM10699_52430	COG1073	alpha beta
AM10699_52470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AM10699_52520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM10699_52520	COG4651	solute:proton antiporter activity
AM10699_52530	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM10699_52540	COG1234	tRNA 3'-trailer cleavage
AM10699_52550	COG0196	riboflavin kinase activity
AM10699_52560	COG0714	Associated with various cellular activities
AM10699_52580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AM10699_52630	COG1104	cysteine desulfurase activity
AM10699_52820	COG0741	lytic transglycosylase activity
AM10699_52820	COG0739	heme binding
AM10699_52820	COG1196	nuclear chromosome segregation
AM10699_52840	COG5001	Diguanylate cyclase
AM10699_52840	COG1716	ATPase activity
AM10699_52850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM10699_52870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM10699_52900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AM10699_52920	COG1252	NADH dehydrogenase
AM10699_52930	COG0450	alkyl hydroperoxide reductase
AM10699_52940	COG0463	Glycosyl transferase, family 2
AM10699_52970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AM10699_53000	COG2226	methyltransferase
AM10699_53100	COG0726	polysaccharide deacetylase
AM10699_53130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM10699_53140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AM10699_53160	COG0640	Transcriptional regulator
AM10699_53190	COG2852	Protein conserved in bacteria
AM10699_53220	COG2197	response regulator
AM10699_53240	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AM10699_53260	COG0393	Putative heavy-metal-binding
AM10699_53340	COG0247	lactate metabolic process
AM10699_53350	COG0277	FAD linked oxidase domain protein
AM10699_53380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM10699_53410	COG4115	mRNA cleavage
AM10699_53480	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM10699_53560	COG0497	DNA recombination
AM10699_53600	COG0237	dephospho-CoA kinase activity
AM10699_53740	COG1053	succinate dehydrogenase
AM10699_53770	COG1309	transcriptional regulator
AM10699_53780	COG3152	Membrane
AM10699_53800	COG2267	carboxylic ester hydrolase activity
AM10699_53810	COG2723	6-phospho-beta-galactosidase activity
AM10699_53820	COG0515	serine threonine protein kinase
AM10699_53820	COG3266	domain, Protein
AM10699_53870	COG2954	triphosphatase activity
AM10699_53890	COG5002	protein histidine kinase activity
AM10699_53900	COG1981	membrane
AM10699_53910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AM10699_53940	COG1196	nuclear chromosome segregation
AM10699_53990	COG0489	protein tyrosine kinase activity
AM10699_54030	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AM10699_54040	COG3250	beta-galactosidase activity
AM10699_54050	COG3291	Pkd domain containing protein
AM10699_54080	COG4122	O-methyltransferase activity
AM10699_54090	COG0515	serine threonine protein kinase
AM10699_54090	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_54100	COG0515	serine threonine protein kinase
AM10699_54100	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_54150	COG0457	Tetratricopeptide repeat
AM10699_54200	COG0010	Belongs to the arginase family
AM10699_54210	COG0375	protein maturation
AM10699_54250	COG1116	anion transmembrane transporter activity
AM10699_54270	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM10699_54280	COG3266	domain, Protein
AM10699_54280	COG0515	serine threonine protein kinase
AM10699_54310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AM10699_54360	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
AM10699_54390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM10699_54400	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AM10699_54420	COG0717	Belongs to the dCTP deaminase family
AM10699_54430	COG3751	2OG-Fe(II) oxygenase superfamily
AM10699_54440	COG2099	Precorrin-6x reductase
AM10699_54450	COG1716	ATPase activity
AM10699_54450	COG5001	Diguanylate cyclase
AM10699_54460	COG0335	large ribosomal subunit rRNA binding
AM10699_54470	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AM10699_54480	COG0250	Participates in transcription elongation, termination and antitermination
AM10699_54490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AM10699_54500	COG0081	regulation of translation
AM10699_54510	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AM10699_54520	COG0222	ribosome binding
AM10699_54530	COG1799	cell septum assembly
AM10699_54560	COG1716	ATPase activity
AM10699_54560	COG1131	(ABC) transporter
AM10699_54560	COG0842	Transport permease protein
AM10699_54570	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AM10699_54580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM10699_54590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AM10699_54600	COG3409	Peptidoglycan-binding domain 1 protein
AM10699_54600	COG3429	Glucose-6-phosphate dehydrogenase subunit
AM10699_54620	COG1797	cobyrinic acid a,c-diamide synthase activity
AM10699_54640	COG0632	four-way junction helicase activity
AM10699_54680	COG0596	Alpha beta hydrolase
AM10699_54720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AM10699_54720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM10699_54740	COG2119	membrane
AM10699_54750	COG2119	membrane
AM10699_54810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM10699_54830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM10699_54850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM10699_54890	COG0163	prenyltransferase activity
AM10699_54930	COG0504	CTP synthase activity
AM10699_54940	COG1940	carbohydrate kinase activity
AM10699_54950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AM10699_55000	COG1253	flavin adenine dinucleotide binding
AM10699_55020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AM10699_55100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM10699_55130	COG4243	Vitamin k epoxide reductase
AM10699_55140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AM10699_55150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AM10699_55170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM10699_55210	COG0601	transmembrane transport
AM10699_55220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AM10699_55280	COG4636	protein conserved in cyanobacteria
AM10699_55320	COG1357	PFAM Pentapeptide repeats (8 copies)
AM10699_55320	COG0515	serine threonine protein kinase
AM10699_55330	COG1175	transmembrane transport
AM10699_55430	COG1131	(ABC) transporter
AM10699_55530	COG1011	Hydrolase
AM10699_55570	COG2223	nitrite transmembrane transporter activity
AM10699_55580	COG3659	wide pore channel activity
AM10699_55590	COG0243	molybdopterin cofactor binding
AM10699_55600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AM10699_55610	COG0778	Nitroreductase
AM10699_55730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AM10699_55750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM10699_55830	COG2166	iron-sulfur cluster assembly
AM10699_55840	COG0523	cobalamin synthesis protein
AM10699_55970	COG3220	belongs to the UPF0276 family
AM10699_56020	COG0523	cobalamin synthesis protein
AM10699_56040	COG2197	response regulator
AM10699_56100	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM10699_56170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM10699_56190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM10699_56190	COG4451	ribulose bisphosphate carboxylase, small
AM10699_56200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM10699_56220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM10699_56230	COG0302	gtp cyclohydrolase
AM10699_56240	COG0523	cobalamin synthesis protein
AM10699_56310	COG3657	addiction module killer protein
AM10699_56370	COG0523	cobalamin synthesis protein
AM10699_56380	COG0113	porphobilinogen synthase activity
AM10699_56390	COG3443	Belongs to the bacterial solute-binding protein 9 family
AM10699_56390	COG0803	Belongs to the bacterial solute-binding protein 9 family
AM10699_56400	COG1121	(ABC) transporter
AM10699_56410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM10699_56430	COG0584	glycerophosphoryl diester phosphodiesterase
AM10699_56470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AM10699_56480	COG1472	Belongs to the glycosyl hydrolase 3 family
AM10699_56530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AM10699_56540	COG0321	lipoyl(octanoyl) transferase activity
AM10699_56550	COG0314	molybdopterin synthase activity
AM10699_56580	COG0706	membrane insertase activity
AM10699_56600	COG0594	ribonuclease P activity
AM10699_56610	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_56620	COG2124	cytochrome p450
AM10699_56660	COG2815	serine threonine protein kinase
AM10699_56660	COG0515	serine threonine protein kinase
AM10699_56840	COG0739	heme binding
AM10699_56940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM10699_56940	COG0515	serine threonine protein kinase
AM10699_56950	COG0515	serine threonine protein kinase
AM10699_56950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM10699_57000	COG0515	serine threonine protein kinase
AM10699_57000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM10699_57370	COG4974	Belongs to the 'phage' integrase family
AM10699_57390	COG0784	Response regulator, receiver
AM10699_57390	COG2205	protein histidine kinase activity
AM10699_57430	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_57460	COG3093	addiction module antidote protein HigA
AM10699_57830	COG0572	uridine kinase
AM10699_57860	COG0582	viral genome integration into host DNA
AM10699_57920	COG3012	SEC-C Motif Domain Protein
AM10699_57960	COG1410	methionine synthase
AM10699_57960	COG0646	methionine synthase
AM10699_57980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM10699_58000	COG4942	peptidase
AM10699_58010	COG0302	gtp cyclohydrolase
AM10699_58040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM10699_58050	COG0215	cysteine-tRNA ligase activity
AM10699_58080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM10699_58140	COG0640	Transcriptional regulator
AM10699_58150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM10699_58170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM10699_58190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM10699_58210	COG0523	cobalamin synthesis protein
AM10699_58230	COG0735	belongs to the Fur family
AM10699_58290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM10699_58300	COG0625	glutathione transferase activity
AM10699_58350	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM10699_58360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM10699_58370	COG0811	peptide transport
AM10699_58380	COG0848	biopolymer transport protein
AM10699_58400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM10699_58430	COG0523	cobalamin synthesis protein
AM10699_58570	COG0823	Involved in the tonB-independent uptake of proteins
AM10699_58610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_58620	COG0776	regulation of translation
AM10699_58810	COG1960	acyl-CoA dehydrogenase activity
AM10699_59070	COG1475	DNA binding
AM10699_59080	COG1192	Involved in chromosome partitioning
AM10699_59200	COG1484	DNA-dependent DNA replication
AM10699_59270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM10699_59280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM10699_59300	COG1799	cell septum assembly
AM10699_59330	COG1662	PFAM IS1 transposase
AM10699_59350	COG3547	Transposase (IS116 IS110 IS902 family)
AM10699_59430	COG1192	Involved in chromosome partitioning
AM10699_59540	COG3903	Transcriptional regulator
AM10699_59540	COG2319	Wd-40 repeat
AM10699_59600	COG3547	Transposase (IS116 IS110 IS902 family)
AM10699_59640	COG3093	addiction module antidote protein HigA
AM10699_59700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM10699_59710	COG1525	nuclease
AM10699_59980	COG4974	Belongs to the 'phage' integrase family
AM10699_60060	COG0582	viral genome integration into host DNA
AM10699_60070	COG2319	Wd-40 repeat
AM10699_60070	COG5635	Nacht domain
AM10699_60110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM10699_60200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM10699_60210	COG3422	double-strand break repair
AM10699_60230	COG1525	nuclease
AM10699_60250	COG2319	Wd-40 repeat
AM10699_60250	COG3903	Transcriptional regulator
AM10699_60640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_60750	COG1484	DNA-dependent DNA replication
AM10699_60760	COG4584	PFAM Integrase catalytic
AM10699_60820	COG2340	Cysteine-rich secretory protein family
AM10699_61010	COG1475	DNA binding
AM10699_61020	COG1192	Involved in chromosome partitioning
AM10699_61030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM10699_61050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AM10699_61060	COG0583	DNA-binding transcription factor activity
AM10699_61140	COG0640	Transcriptional regulator
AM10699_61150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM10699_61180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM10699_61200	COG0523	cobalamin synthesis protein
AM10699_61220	COG0735	belongs to the Fur family
AM10699_61240	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AM10699_61310	COG5433	transposase activity
AM10699_61330	COG0582	viral genome integration into host DNA
AM10699_61400	COG1192	Involved in chromosome partitioning
AM10699_61460	COG0778	Nitroreductase
AM10699_61580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AM10699_61600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM10699_61640	COG0366	Alpha amylase catalytic
AM10699_61650	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_61660	COG0583	DNA-binding transcription factor activity
AM10699_61690	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_61740	COG0583	DNA-binding transcription factor activity
AM10699_61750	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_61800	COG0454	-acetyltransferase
AM10699_61880	COG4974	Belongs to the 'phage' integrase family
AM10699_61920	COG0633	Ferredoxin
AM10699_61950	COG0633	Ferredoxin
AM10699_62060	COG0776	regulation of translation
AM10699_62110	COG2197	response regulator
AM10699_62120	COG4585	Histidine kinase
AM10699_62140	COG0784	Response regulator, receiver
AM10699_62140	COG2198	Histidine kinase
AM10699_62140	COG2205	protein histidine kinase activity
AM10699_62170	COG5001	Diguanylate cyclase
AM10699_62170	COG2203	Gaf domain
AM10699_62170	COG3706	GGDEF domain
AM10699_62170	COG4251	negative regulation of phosphorylation
AM10699_62190	COG3119	arylsulfatase activity
AM10699_62210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM10699_62240	COG2272	Belongs to the type-B carboxylesterase lipase family
AM10699_62320	COG2197	response regulator
AM10699_62370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM10699_62380	COG0625	glutathione transferase activity
AM10699_62400	COG2855	membrane
AM10699_62430	COG2046	Belongs to the sulfate adenylyltransferase family
AM10699_62440	COG3273	potassium ion transport
AM10699_62440	COG0471	metal ion transport
AM10699_62540	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_62580	COG0300	oxidoreductase activity
AM10699_62590	COG0300	oxidoreductase activity
AM10699_62610	COG0302	gtp cyclohydrolase
AM10699_62630	COG4942	peptidase
AM10699_62640	COG2027	D-alanyl-D-alanine carboxypeptidase
AM10699_62670	COG1410	methionine synthase
AM10699_62670	COG0646	methionine synthase
AM10699_62690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AM10699_62700	COG0523	cobalamin synthesis protein
AM10699_62710	COG0302	gtp cyclohydrolase
AM10699_62720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM10699_62730	COG4451	ribulose bisphosphate carboxylase, small
AM10699_62730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM10699_62770	COG0215	cysteine-tRNA ligase activity
AM10699_62780	COG0811	peptide transport
AM10699_62790	COG0848	biopolymer transport protein
AM10699_62830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM10699_62840	COG1121	(ABC) transporter
AM10699_62850	COG0390	transport system, permease component
AM10699_62860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM10699_62870	COG0523	cobalamin synthesis protein
AM10699_62880	COG0358	DNA primase activity
AM10699_62940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AM10699_62950	COG4279	zinc finger
AM10699_62970	COG4249	Peptidase C14 caspase catalytic subunit p20
AM10699_62970	COG2319	Wd-40 repeat
AM10699_62990	COG0667	Aldo Keto reductase
AM10699_63030	COG0724	RNA recognition motif
AM10699_63070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM10699_63080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM10699_63090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM10699_63110	COG1799	cell septum assembly
AM10699_63120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM10699_63140	COG0745	RESPONSE REGULATOR receiver
AM10699_63180	COG2226	methyltransferase
AM10699_63270	COG2994	toxin metabolic process
AM10699_63310	COG1024	Enoyl-CoA hydratase
AM10699_63310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AM10699_63320	COG3903	Transcriptional regulator
AM10699_63320	COG2319	Wd-40 repeat
AM10699_63340	COG0450	alkyl hydroperoxide reductase
AM10699_63360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM10699_63370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM10699_63470	COG1475	DNA binding
AM10699_63570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM10699_63660	COG0270	DNA (cytosine-5-)-methyltransferase activity
AM10699_63820	COG0776	regulation of translation
AM10699_63830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_64120	COG4249	Peptidase C14 caspase catalytic subunit p20
AM10699_64120	COG2319	Wd-40 repeat
AM10699_64170	COG3012	SEC-C Motif Domain Protein
AM10699_64180	COG2319	Wd-40 repeat
AM10699_64180	COG4249	Peptidase C14 caspase catalytic subunit p20
AM10699_64430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AM10699_64590	COG3629	intracellular signal transduction
AM10699_64590	COG3903	Transcriptional regulator
AM10699_64700	COG0739	heme binding
AM10699_64720	COG1595	DNA-templated transcription, initiation
AM10699_64830	COG1799	cell septum assembly
AM10699_64840	COG0668	transmembrane transport
AM10699_64870	COG0724	RNA recognition motif
AM10699_64880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM10699_64900	COG0583	DNA-binding transcription factor activity
AM10699_64930	COG0583	DNA-binding transcription factor activity
AM10699_64960	COG1309	transcriptional regulator
AM10699_65110	COG1032	radical SAM domain protein
AM10699_65250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM10699_65260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM10699_65270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM10699_65310	COG0724	RNA recognition motif
AM10699_65390	COG1902	pentaerythritol trinitrate reductase activity
AM10699_65460	COG3744	PilT protein domain protein
AM10699_65470	COG0582	viral genome integration into host DNA
AM10699_65490	COG5001	Diguanylate cyclase
AM10699_65500	COG0784	Response regulator, receiver
AM10699_65500	COG2205	protein histidine kinase activity
AM10699_65500	COG5002	protein histidine kinase activity
AM10699_65510	COG1716	ATPase activity
AM10699_65510	COG5001	Diguanylate cyclase
AM10699_65610	COG5000	phosphorelay sensor kinase activity
AM10699_65610	COG5002	protein histidine kinase activity
AM10699_65680	COG1484	DNA-dependent DNA replication
AM10699_65690	COG4584	PFAM Integrase catalytic
AM10699_65770	COG0135	phosphoribosylanthranilate isomerase activity
AM10699_65780	COG1484	DNA-dependent DNA replication
AM10699_65840	COG2211	Major facilitator Superfamily
AM10699_65880	COG4977	sequence-specific DNA binding
AM10699_65880	COG1917	Cupin 2, conserved barrel domain protein
AM10699_65980	COG2226	methyltransferase
AM10699_65990	COG0288	reversible hydration of carbon dioxide
AM10699_66030	COG2274	protein secretion by the type I secretion system
AM10699_66130	COG1192	Involved in chromosome partitioning
AM10699_66170	COG0557	exoribonuclease II activity
AM10699_66200	COG1028	Short-chain dehydrogenase reductase Sdr
AM10699_66210	COG1733	regulation of RNA biosynthetic process
AM10699_66310	COG1917	Cupin 2, conserved barrel domain protein
AM10699_66310	COG4977	sequence-specific DNA binding
AM10699_66410	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AM10699_66440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AM10699_66580	COG4974	Belongs to the 'phage' integrase family
AM10699_66710	COG0455	bacterial-type flagellum organization
AM10699_66730	COG0582	viral genome integration into host DNA
AM10699_66940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_67130	COG2319	Wd-40 repeat
AM10699_67130	COG4249	Peptidase C14 caspase catalytic subunit p20
AM10699_67430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AM10699_67890	COG2161	toxin-antitoxin pair type II binding
AM10699_67980	COG4638	Rieske (2fe-2S)