locus-tag	class	description
Clocl_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Clocl_0002	COG0592	DNA-directed DNA polymerase activity
Clocl_0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Clocl_0006	COG0187	DNA topoisomerase II activity
Clocl_0007	COG1192	Involved in chromosome partitioning
Clocl_0008	COG1475	DNA binding
Clocl_0011	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Clocl_0014	COG2814	Major facilitator Superfamily
Clocl_0015	COG0493	'glutamate synthase
Clocl_0016	COG0069	glutamate synthase activity
Clocl_0016	COG0070	glutamate synthase
Clocl_0016	COG0067	glutamate synthase
Clocl_0018	COG2373	Large extracellular alpha-helical protein
Clocl_0020	COG2720	vancomycin resistance protein
Clocl_0023	COG0674	pyruvate-flavodoxin oxidoreductase activity
Clocl_0023	COG1013	pyruvate-flavodoxin oxidoreductase activity
Clocl_0023	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Clocl_0023	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Clocl_0028	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Clocl_0029	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Clocl_0034	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Clocl_0035	COG1802	Transcriptional regulator
Clocl_0036	COG2608	mercury ion transmembrane transporter activity
Clocl_0037	COG2201	protein-glutamate methylesterase activity
Clocl_0038	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Clocl_0052	COG0714	Associated with various cellular activities
Clocl_0053	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Clocl_0054	COG3409	Peptidoglycan-binding domain 1 protein
Clocl_0054	COG3773	Cell wall hydrolase
Clocl_0055	COG2959	enzyme of heme biosynthesis
Clocl_0063	COG3872	metal-dependent enzyme
Clocl_0064	COG2890	protein-(glutamine-N5) methyltransferase activity
Clocl_0065	COG0628	permease
Clocl_0066	COG4656	Part of a membrane complex involved in electron transport
Clocl_0067	COG4658	electron transport chain
Clocl_0068	COG4659	FMN binding
Clocl_0069	COG4660	Part of a membrane complex involved in electron transport
Clocl_0070	COG4657	Part of a membrane complex involved in electron transport
Clocl_0071	COG2878	Part of a membrane complex involved in electron transport
Clocl_0075	COG2309	aminopeptidase activity
Clocl_0076	COG1164	Oligoendopeptidase f
Clocl_0079	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Clocl_0079	COG0493	'glutamate synthase
Clocl_0082	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Clocl_0085	COG0590	tRNA wobble adenosine to inosine editing
Clocl_0087	COG0534	Mate efflux family protein
Clocl_0088	COG2755	lipolytic protein G-D-S-L family
Clocl_0093	COG2002	toxin-antitoxin pair type II binding
Clocl_0107	COG1394	ATPase activity, coupled to movement of substances
Clocl_0108	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Clocl_0109	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Clocl_0112	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
Clocl_0113	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Clocl_0114	COG1269	ATP hydrolysis coupled proton transport
Clocl_0117	COG1012	belongs to the aldehyde dehydrogenase family
Clocl_0117	COG1454	alcohol dehydrogenase
Clocl_0118	COG0628	permease
Clocl_0120	COG1605	Chorismate mutase
Clocl_0120	COG0077	Prephenate dehydratase
Clocl_0122	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Clocl_0123	COG0359	binds to the 23S rRNA
Clocl_0124	COG0305	Participates in initiation and elongation during chromosome replication
Clocl_0125	COG0037	tRNA processing
Clocl_0126	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Clocl_0127	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Clocl_0130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Clocl_0134	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Clocl_0137	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Clocl_0138	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Clocl_0139	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Clocl_0142	COG2226	methyltransferase
Clocl_0154	COG0640	Transcriptional regulator
Clocl_0155	COG0798	PFAM Bile acid sodium symporter
Clocl_0167	COG0489	protein tyrosine kinase activity
Clocl_0170	COG0735	belongs to the Fur family
Clocl_0181	COG3706	GGDEF domain
Clocl_0189	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Clocl_0191	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Clocl_0192	COG1397	ADP-ribosylglycohydrolase
Clocl_0197	COG0556	nucleotide-excision repair
Clocl_0203	COG4974	Belongs to the 'phage' integrase family
Clocl_0227	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Clocl_0228	COG0640	Transcriptional regulator
Clocl_0247	COG3706	GGDEF domain
Clocl_0258	COG1397	ADP-ribosylglycohydrolase
Clocl_0263	COG1396	sequence-specific DNA binding
Clocl_0282	COG3693	PFAM glycoside hydrolase, family 10
Clocl_0285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Clocl_0286	COG0428	transporter
Clocl_0287	COG0009	L-threonylcarbamoyladenylate synthase
Clocl_0289	COG0698	ribose 5-phosphate isomerase
Clocl_0290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Clocl_0291	COG2131	deaminase
Clocl_0292	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Clocl_0293	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Clocl_0296	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Clocl_0297	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Clocl_0298	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Clocl_0299	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Clocl_0300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Clocl_0301	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Clocl_0302	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Clocl_0305	COG1361	Conserved repeat domain
Clocl_0307	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Clocl_0308	COG2385	sporulation resulting in formation of a cellular spore
Clocl_0313	COG1609	Transcriptional regulator
Clocl_0315	COG4786	Flagellar basal body rod
Clocl_0318	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Clocl_0319	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Clocl_0320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Clocl_0321	COG2088	sporulation resulting in formation of a cellular spore
Clocl_0322	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Clocl_0323	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Clocl_0324	COG0193	aminoacyl-tRNA hydrolase activity
Clocl_0325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Clocl_0327	COG2002	toxin-antitoxin pair type II binding
Clocl_0328	COG1376	ErfK ybiS ycfS ynhG family protein
Clocl_0329	COG3956	TIGRFAM MazG family protein
Clocl_0330	COG0776	regulation of translation
Clocl_0331	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Clocl_0335	COG1098	S1 RNA binding domain
Clocl_0341	COG0569	domain protein
Clocl_0343	COG3328	transposase activity
Clocl_0344	COG2963	transposase activity
Clocl_0345	COG3436	PFAM IS66 Orf2 family protein
Clocl_0350	COG2755	lipolytic protein G-D-S-L family
Clocl_0350	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clocl_0352	COG0454	-acetyltransferase
Clocl_0356	COG0577	efflux transmembrane transporter activity
Clocl_0357	COG1136	(ABC) transporter
Clocl_0358	COG2205	protein histidine kinase activity
Clocl_0360	COG1132	(ABC) transporter
Clocl_0361	COG1132	(ABC) transporter
Clocl_0362	COG0310	cobalt ion transport
Clocl_0364	COG1122	ATPase activity
Clocl_0367	COG0546	phosphoglycolate phosphatase activity
Clocl_0368	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Clocl_0375	COG0484	heat shock protein binding
Clocl_0377	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Clocl_0378	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Clocl_0386	COG2972	Histidine kinase
Clocl_0387	COG2207	Transcriptional regulator
Clocl_0387	COG4753	response regulator
Clocl_0391	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Clocl_0393	COG1607	acyl-coa hydrolase
Clocl_0394	COG0791	NLP P60 protein
Clocl_0394	COG1388	LysM domain
Clocl_0395	COG2244	polysaccharide biosynthetic process
Clocl_0396	COG0071	Belongs to the small heat shock protein (HSP20) family
Clocl_0398	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Clocl_0400	COG0110	maltose O-acetyltransferase activity
Clocl_0401	COG0438	transferase activity, transferring glycosyl groups
Clocl_0405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Clocl_0405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Clocl_0406	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Clocl_0407	COG0864	Transcriptional regulator
Clocl_0408	COG2337	Toxic component of a toxin-antitoxin (TA) module
Clocl_0411	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Clocl_0413	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Clocl_0414	COG3959	Transketolase, thiamine diphosphate binding domain
Clocl_0415	COG3958	Transketolase
Clocl_0441	COG1131	(ABC) transporter
Clocl_0444	COG0714	Associated with various cellular activities
Clocl_0449	COG3328	transposase activity
Clocl_0453	COG0745	RESPONSE REGULATOR receiver
Clocl_0456	COG1131	(ABC) transporter
Clocl_0463	COG1609	Transcriptional regulator
Clocl_0464	COG3459	Glycosyltransferase 36 associated
Clocl_0465	COG3459	Glycosyltransferase 36 associated
Clocl_0467	COG4733	cellulase activity
Clocl_0469	COG0745	RESPONSE REGULATOR receiver
Clocl_0470	COG5002	protein histidine kinase activity
Clocl_0472	COG0210	DNA helicase
Clocl_0475	COG1609	Transcriptional regulator
Clocl_0476	COG0454	-acetyltransferase
Clocl_0484	COG3328	transposase activity
Clocl_0489	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Clocl_0490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Clocl_0492	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Clocl_0493	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Clocl_0494	COG3842	ATPase activity
Clocl_0495	COG2508	Transcriptional regulator
Clocl_0496	COG2884	Cell division ATP-binding protein ftsE
Clocl_0497	COG2177	Part of the ABC transporter FtsEX involved in
Clocl_0498	COG0739	heme binding
Clocl_0499	COG0793	Belongs to the peptidase S41A family
Clocl_0499	COG3409	Peptidoglycan-binding domain 1 protein
Clocl_0501	COG2226	methyltransferase
Clocl_0502	COG1278	Cold shock
Clocl_0503	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Clocl_0513	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Clocl_0514	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Clocl_0515	COG4208	sulfate ABC transporter
Clocl_0518	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
Clocl_0522	COG0745	RESPONSE REGULATOR receiver
Clocl_0524	COG4166	transmembrane transport
Clocl_0527	COG0860	N-Acetylmuramoyl-L-alanine amidase
Clocl_0533	COG3942	CHAP domain
Clocl_0533	COG1388	LysM domain
Clocl_0534	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Clocl_0535	COG0488	(ABC) transporter
Clocl_0539	COG0287	Prephenate dehydrogenase
Clocl_0540	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Clocl_0545	COG3880	PFAM UvrB UvrC protein
Clocl_0546	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Clocl_0547	COG0542	response to heat
Clocl_0554	COG1305	Transglutaminase-like
Clocl_0556	COG0714	Associated with various cellular activities
Clocl_0560	COG5002	protein histidine kinase activity
Clocl_0560	COG0784	Response regulator, receiver
Clocl_0562	COG1215	transferase activity, transferring glycosyl groups
Clocl_0564	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Clocl_0565	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Clocl_0567	COG1329	Transcriptional regulator
Clocl_0568	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Clocl_0569	COG4555	ABC transporter
Clocl_0570	COG1668	transmembrane transport
Clocl_0571	COG4191	Histidine kinase
Clocl_0572	COG5002	protein histidine kinase activity
Clocl_0573	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Clocl_0574	COG2340	Cysteine-rich secretory protein family
Clocl_0575	COG0534	Mate efflux family protein
Clocl_0584	COG0564	pseudouridine synthase activity
Clocl_0585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Clocl_0588	COG0251	oxidation-reduction process
Clocl_0589	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Clocl_0596	COG2183	response to ionizing radiation
Clocl_0603	COG0785	Cytochrome C biogenesis protein
Clocl_0604	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Clocl_0606	COG0492	ferredoxin-NADP+ reductase activity
Clocl_0608	COG0446	pyridine nucleotide-disulphide oxidoreductase
Clocl_0612	COG1595	DNA-templated transcription, initiation
Clocl_0618	COG1361	Conserved repeat domain
Clocl_0619	COG0433	COG0433 Predicted ATPase
Clocl_0620	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Clocl_0623	COG1181	Belongs to the D-alanine--D-alanine ligase family
Clocl_0624	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Clocl_0626	COG0018	arginyl-trna synthetase
Clocl_0628	COG1013	pyruvate-flavodoxin oxidoreductase activity
Clocl_0628	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Clocl_0628	COG0674	pyruvate-flavodoxin oxidoreductase activity
Clocl_0628	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Clocl_0631	COG0793	Belongs to the peptidase S41A family
Clocl_0634	COG0504	CTP synthase activity
Clocl_0636	COG1285	pathogenesis
Clocl_0637	COG1982	Orn Lys Arg decarboxylase major
Clocl_0638	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Clocl_0639	COG1131	(ABC) transporter
Clocl_0643	COG3949	Membrane
Clocl_0646	COG0129	dihydroxy-acid dehydratase activity
Clocl_0647	COG0028	Belongs to the TPP enzyme family
Clocl_0649	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Clocl_0650	COG0250	Participates in transcription elongation, termination and antitermination
Clocl_0651	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Clocl_0652	COG0081	regulation of translation
Clocl_0653	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Clocl_0655	COG0085	RNA polymerase activity
Clocl_0656	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Clocl_0657	COG1358	cellular component organization or biogenesis
Clocl_0658	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Clocl_0659	COG0049	tRNA binding
Clocl_0660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Clocl_0661	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Clocl_0665	COG2720	vancomycin resistance protein
Clocl_0666	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Clocl_0667	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Clocl_0668	COG0322	excinuclease ABC activity
Clocl_0670	COG0544	peptidyl-prolyl cis-trans isomerase activity
Clocl_0671	COG0740	serine-type endopeptidase activity
Clocl_0672	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Clocl_0674	COG0470	DNA polymerase III
Clocl_0674	COG1067	ATP-dependent peptidase activity
Clocl_0675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Clocl_0676	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Clocl_0677	COG0741	lytic transglycosylase activity
Clocl_0680	COG0613	PHP domain protein
Clocl_0682	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Clocl_0698	COG3655	Transcriptional regulator
Clocl_0713	COG0484	heat shock protein binding
Clocl_0714	COG3328	transposase activity
Clocl_0722	COG4166	transmembrane transport
Clocl_0723	COG4585	Histidine kinase
Clocl_0724	COG2197	response regulator
Clocl_0727	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Clocl_0733	COG0596	Alpha beta hydrolase
Clocl_0734	COG2207	Transcriptional regulator
Clocl_0734	COG3708	Transcriptional regulator
Clocl_0742	COG2813	Specifically methylates the guanine in position
Clocl_0743	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Clocl_0755	COG3546	catalase activity
Clocl_0758	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Clocl_0759	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Clocl_0761	COG0426	domain, Protein
Clocl_0761	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Clocl_0763	COG0840	transmembrane signaling receptor activity
Clocl_0764	COG0840	transmembrane signaling receptor activity
Clocl_0766	COG4512	PFAM Accessory gene regulator B
Clocl_0769	COG1131	(ABC) transporter
Clocl_0773	COG5002	protein histidine kinase activity
Clocl_0776	COG0295	cytidine deaminase activity
Clocl_0779	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Clocl_0780	COG5012	cobalamin binding
Clocl_0782	COG0523	cobalamin synthesis protein
Clocl_0785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Clocl_0787	COG1609	Transcriptional regulator
Clocl_0790	COG1879	ABC-type sugar transport system periplasmic component
Clocl_0791	COG1172	Belongs to the binding-protein-dependent transport system permease family
Clocl_0792	COG1129	ABC transporter
Clocl_0797	COG1690	Belongs to the RtcB family
Clocl_0798	COG0084	hydrolase, TatD family'
Clocl_0799	COG1234	tRNA 3'-trailer cleavage
Clocl_0801	COG2357	RelA SpoT domain protein
Clocl_0803	COG1132	(ABC) transporter
Clocl_0804	COG1132	(ABC) transporter
Clocl_0806	COG1151	hydroxylamine reductase activity
Clocl_0808	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_0825	COG3328	transposase activity
Clocl_0865	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Clocl_0867	COG0450	alkyl hydroperoxide reductase
Clocl_0868	COG3634	alkyl hydroperoxide reductase activity
Clocl_0871	COG4166	transmembrane transport
Clocl_0872	COG4608	Belongs to the ABC transporter superfamily
Clocl_0873	COG0444	Belongs to the ABC transporter superfamily
Clocl_0874	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Clocl_0875	COG0601	transmembrane transport
Clocl_0877	COG0450	alkyl hydroperoxide reductase
Clocl_0895	COG3436	PFAM IS66 Orf2 family protein
Clocl_0896	COG2963	transposase activity
Clocl_0901	COG4124	Belongs to the glycosyl hydrolase 26 family
Clocl_0906	COG4447	cellulose binding
Clocl_0908	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Clocl_0909	COG2116	formate transmembrane transporter activity
Clocl_0911	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Clocl_0914	COG1592	Rubrerythrin
Clocl_0917	COG1151	hydroxylamine reductase activity
Clocl_0923	COG3250	beta-galactosidase activity
Clocl_0924	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Clocl_0925	COG0662	Cupin 2, conserved barrel domain protein
Clocl_0928	COG1979	alcohol dehydrogenase
Clocl_0929	COG0246	Mannitol dehydrogenase
Clocl_0932	COG0840	transmembrane signaling receptor activity
Clocl_0934	COG0735	belongs to the Fur family
Clocl_0938	COG0318	PFAM AMP-dependent synthetase and ligase
Clocl_0943	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Clocl_0952	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Clocl_0956	COG1278	Cold shock
Clocl_0958	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Clocl_0959	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Clocl_0965	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Clocl_0967	COG0159	tryptophan synthase activity
Clocl_0969	COG1598	PFAM Uncharacterised protein family UPF0150
Clocl_0971	COG1253	flavin adenine dinucleotide binding
Clocl_0973	COG0835	chemotaxis
Clocl_0974	COG0840	transmembrane signaling receptor activity
Clocl_0975	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Clocl_0976	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Clocl_0977	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Clocl_0977	COG2111	Na H antiporter
Clocl_0978	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Clocl_0979	COG3260	NADH ubiquinone oxidoreductase 20
Clocl_0981	COG3261	NADH dehydrogenase
Clocl_0981	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Clocl_0983	COG0375	protein maturation
Clocl_0985	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Clocl_0987	COG0409	Hydrogenase expression formation protein
Clocl_0989	COG0494	nUDIX hydrolase
Clocl_0991	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Clocl_0992	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Clocl_0996	COG0133	tryptophan synthase activity
Clocl_0998	COG0803	Belongs to the bacterial solute-binding protein 9 family
Clocl_1000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Clocl_1002	COG1131	(ABC) transporter
Clocl_1004	COG4464	protein tyrosine phosphatase activity
Clocl_1010	COG1028	Short-chain dehydrogenase reductase Sdr
Clocl_1011	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Clocl_1012	COG3959	Transketolase, thiamine diphosphate binding domain
Clocl_1013	COG3958	Transketolase
Clocl_1014	COG1215	transferase activity, transferring glycosyl groups
Clocl_1018	COG3475	LICD family
Clocl_1019	COG1213	nucleotidyl transferase
Clocl_1020	COG1086	Polysaccharide biosynthesis protein
Clocl_1021	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Clocl_1024	COG1442	glycosyl transferase family 8
Clocl_1024	COG1216	Glycosyl transferase, family 2
Clocl_1027	COG1028	Short-chain dehydrogenase reductase Sdr
Clocl_1028	COG0495	leucyl-tRNA aminoacylation
Clocl_1031	COG1609	Transcriptional regulator
Clocl_1034	COG0714	Associated with various cellular activities
Clocl_1038	COG3620	sequence-specific DNA binding
Clocl_1039	COG0534	Mate efflux family protein
Clocl_1041	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Clocl_1042	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_1044	COG1361	Conserved repeat domain
Clocl_1046	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Clocl_1047	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clocl_1047	COG2755	lipolytic protein G-D-S-L family
Clocl_1048	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Clocl_1049	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Clocl_1050	COG2954	triphosphatase activity
Clocl_1053	COG4447	cellulose binding
Clocl_1054	COG1191	sigma factor activity
Clocl_1055	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Clocl_1056	COG5297	Belongs to the glycosyl hydrolase family 6
Clocl_1057	COG1686	Belongs to the peptidase S11 family
Clocl_1058	COG0450	alkyl hydroperoxide reductase
Clocl_1059	COG0745	RESPONSE REGULATOR receiver
Clocl_1066	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Clocl_1067	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Clocl_1068	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Clocl_1068	COG0116	Belongs to the methyltransferase superfamily
Clocl_1069	COG0564	pseudouridine synthase activity
Clocl_1071	COG2373	Large extracellular alpha-helical protein
Clocl_1072	COG1595	DNA-templated transcription, initiation
Clocl_1073	COG0297	glycogen (starch) synthase activity
Clocl_1074	COG0667	Aldo Keto reductase
Clocl_1081	COG1368	sulfuric ester hydrolase activity
Clocl_1087	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Clocl_1088	COG2502	aspartate--ammonia ligase
Clocl_1089	COG0017	Asparaginyl-tRNA synthetase
Clocl_1091	COG0708	Exodeoxyribonuclease III
Clocl_1093	COG1983	PspC domain protein
Clocl_1095	COG5002	protein histidine kinase activity
Clocl_1096	COG2201	protein-glutamate methylesterase activity
Clocl_1097	COG2198	Histidine kinase
Clocl_1097	COG0643	Histidine kinase
Clocl_1102	COG0835	chemotaxis
Clocl_1103	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Clocl_1104	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Clocl_1111	COG0424	maF-like protein
Clocl_1112	COG1077	Cell shape determining protein MreB Mrl
Clocl_1115	COG0768	penicillin binding
Clocl_1116	COG0850	regulation of cytokinetic process
Clocl_1117	COG2894	cell division
Clocl_1118	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Clocl_1119	COG1803	Methylglyoxal synthase
Clocl_1120	COG0739	heme binding
Clocl_1121	COG0517	IMP dehydrogenase activity
Clocl_1121	COG1994	Peptidase M50
Clocl_1123	COG0432	Pfam Uncharacterised protein family UPF0047
Clocl_1126	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Clocl_1126	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Clocl_1127	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Clocl_1131	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Clocl_1132	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Clocl_1133	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Clocl_1134	COG1660	Displays ATPase and GTPase activities
Clocl_1137	COG1481	regulation of sporulation
Clocl_1138	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Clocl_1139	COG1366	Belongs to the anti-sigma-factor antagonist family
Clocl_1140	COG2172	sigma factor antagonist activity
Clocl_1143	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Clocl_1149	COG2195	Cleaves the N-terminal amino acid of tripeptides
Clocl_1153	COG0126	phosphoglycerate kinase activity
Clocl_1154	COG0149	triose-phosphate isomerase activity
Clocl_1155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Clocl_1183	COG3328	transposase activity
Clocl_1192	COG4447	cellulose binding
Clocl_1192	COG4733	cellulase activity
Clocl_1193	COG0148	phosphopyruvate hydratase activity
Clocl_1197	COG0557	exoribonuclease II activity
Clocl_1198	COG1683	Conserved Protein
Clocl_1200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Clocl_1201	COG4472	Bacterial protein of unknown function (DUF965)
Clocl_1202	COG0667	Aldo Keto reductase
Clocl_1203	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Clocl_1204	COG3906	Belongs to the UPF0473 family
Clocl_1208	COG1530	ribonuclease E activity
Clocl_1209	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Clocl_1211	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Clocl_1212	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Clocl_1214	COG1534	Rna-binding protein
Clocl_1218	COG1368	sulfuric ester hydrolase activity
Clocl_1222	COG0165	Argininosuccinate lyase
Clocl_1223	COG0137	argininosuccinate synthase activity
Clocl_1224	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Clocl_1225	COG0632	four-way junction helicase activity
Clocl_1226	COG2255	four-way junction helicase activity
Clocl_1228	COG0860	N-Acetylmuramoyl-L-alanine amidase
Clocl_1228	COG2247	cell wall binding repeat
Clocl_1229	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Clocl_1231	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Clocl_1232	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Clocl_1236	COG0210	DNA helicase
Clocl_1239	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Clocl_1239	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Clocl_1242	COG4209	transmembrane transport
Clocl_1243	COG0395	ABC-type sugar transport system, permease component
Clocl_1245	COG0653	protein targeting
Clocl_1247	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Clocl_1256	COG1850	ribulose-bisphosphate carboxylase activity
Clocl_1257	COG3958	Transketolase
Clocl_1258	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Clocl_1259	COG0525	valine-tRNA ligase activity
Clocl_1260	COG3707	response regulator
Clocl_1261	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Clocl_1262	COG0347	Belongs to the P(II) protein family
Clocl_1263	COG0347	Belongs to the P(II) protein family
Clocl_1267	COG0535	radical SAM domain protein
Clocl_1267	COG1433	Dinitrogenase iron-molybdenum cofactor
Clocl_1271	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Clocl_1271	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Clocl_1272	COG3328	transposase activity
Clocl_1276	COG1136	(ABC) transporter
Clocl_1279	COG2703	oxygen carrier activity
Clocl_1281	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Clocl_1283	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_1287	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Clocl_1291	COG3279	Response regulator of the LytR AlgR family
Clocl_1298	COG4305	rare lipoprotein A
Clocl_1299	COG0725	ABC transporter, periplasmic molybdate-binding protein
Clocl_1300	COG4149	molybdate abc transporter
Clocl_1301	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Clocl_1302	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Clocl_1303	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Clocl_1314	COG0494	nUDIX hydrolase
Clocl_1317	COG2207	Transcriptional regulator
Clocl_1318	COG0436	Aminotransferase
Clocl_1319	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Clocl_1320	COG0072	phenylalanine-tRNA ligase activity
Clocl_1320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Clocl_1322	COG0166	Belongs to the GPI family
Clocl_1323	COG1408	metallophosphoesterase
Clocl_1324	COG0840	transmembrane signaling receptor activity
Clocl_1327	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Clocl_1328	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Clocl_1331	COG1482	cell wall glycoprotein biosynthetic process
Clocl_1332	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Clocl_1333	COG1028	Short-chain dehydrogenase reductase Sdr
Clocl_1339	COG0655	NAD(P)H dehydrogenase (quinone) activity
Clocl_1348	COG1316	TRANSCRIPTIONal
Clocl_1349	COG3279	Response regulator of the LytR AlgR family
Clocl_1351	COG4864	UPF0365 protein
Clocl_1352	COG1030	water channel activity
Clocl_1353	COG3290	protein histidine kinase activity
Clocl_1354	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Clocl_1355	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Clocl_1356	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Clocl_1358	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Clocl_1361	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Clocl_1362	COG0006	proline dipeptidase activity
Clocl_1363	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Clocl_1368	COG3830	Belongs to the UPF0237 family
Clocl_1369	COG2848	UPF0210 protein
Clocl_1370	COG1595	DNA-templated transcription, initiation
Clocl_1374	COG1131	(ABC) transporter
Clocl_1378	COG0535	radical SAM domain protein
Clocl_1381	COG3546	catalase activity
Clocl_1384	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Clocl_1385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Clocl_1386	COG1185	polyribonucleotide nucleotidyltransferase activity
Clocl_1387	COG0612	Peptidase, M16
Clocl_1388	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Clocl_1389	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Clocl_1390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Clocl_1392	COG1459	type II secretion system
Clocl_1400	COG0740	serine-type endopeptidase activity
Clocl_1402	COG1674	ftsk spoiiie
Clocl_1404	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Clocl_1406	COG1418	mRNA catabolic process
Clocl_1407	COG1692	metallophosphoesterase
Clocl_1408	COG2359	stage V sporulation protein S
Clocl_1411	COG2963	transposase activity
Clocl_1412	COG3436	PFAM IS66 Orf2 family protein
Clocl_1413	COG4372	Transposase
Clocl_1417	COG0534	Mate efflux family protein
Clocl_1420	COG1088	dTDP-glucose 4,6-dehydratase activity
Clocl_1424	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Clocl_1426	COG3879	Bacterial protein of unknown function (DUF881)
Clocl_1431	COG1702	phosphate starvation-inducible protein PhoH
Clocl_1432	COG1480	7TM receptor with intracellular HD hydrolase
Clocl_1433	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Clocl_1434	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Clocl_1436	COG1381	Involved in DNA repair and RecF pathway recombination
Clocl_1439	COG1104	cysteine desulfurase activity
Clocl_1440	COG0301	tRNA thio-modification
Clocl_1441	COG2720	vancomycin resistance protein
Clocl_1445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Clocl_1446	COG1305	Transglutaminase-like
Clocl_1448	COG0714	Associated with various cellular activities
Clocl_1449	COG0039	L-malate dehydrogenase activity
Clocl_1450	COG1546	Belongs to the CinA family
Clocl_1450	COG1058	Belongs to the CinA family
Clocl_1451	COG0728	peptidoglycan biosynthetic process
Clocl_1452	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Clocl_1454	COG0330	HflC and HflK could
Clocl_1455	COG0697	spore germination
Clocl_1461	COG5002	protein histidine kinase activity
Clocl_1463	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Clocl_1464	COG0328	RNA-DNA hybrid ribonuclease activity
Clocl_1466	COG1300	Membrane
Clocl_1467	COG4974	Belongs to the 'phage' integrase family
Clocl_1468	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Clocl_1469	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Clocl_1470	COG1686	Belongs to the peptidase S11 family
Clocl_1474	COG0714	Associated with various cellular activities
Clocl_1482	COG2234	aminopeptidase activity
Clocl_1483	COG3620	sequence-specific DNA binding
Clocl_1483	COG0617	tRNA 3'-terminal CCA addition
Clocl_1483	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Clocl_1484	COG1994	Peptidase M50
Clocl_1485	COG0180	Tryptophanyl-tRNA synthetase
Clocl_1487	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Clocl_1489	COG3874	Sporulation protein YtfJ
Clocl_1490	COG1187	pseudouridine synthase activity
Clocl_1492	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Clocl_1493	COG0010	Belongs to the arginase family
Clocl_1494	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Clocl_1496	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Clocl_1498	COG0511	ligase activity, forming carbon-carbon bonds
Clocl_1505	COG4372	Transposase
Clocl_1506	COG3436	PFAM IS66 Orf2 family protein
Clocl_1516	COG2963	transposase activity
Clocl_1517	COG3436	PFAM IS66 Orf2 family protein
Clocl_1527	COG2963	transposase activity
Clocl_1528	COG3436	PFAM IS66 Orf2 family protein
Clocl_1546	COG3436	PFAM IS66 Orf2 family protein
Clocl_1547	COG2963	transposase activity
Clocl_1548	COG0840	transmembrane signaling receptor activity
Clocl_1549	COG0840	transmembrane signaling receptor activity
Clocl_1557	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Clocl_1559	COG1131	(ABC) transporter
Clocl_1560	COG1725	Transcriptional regulator
Clocl_1565	COG0739	heme binding
Clocl_1565	COG0741	lytic transglycosylase activity
Clocl_1565	COG1196	nuclear chromosome segregation
Clocl_1566	COG4733	cellulase activity
Clocl_1566	COG4447	cellulose binding
Clocl_1567	COG5297	Belongs to the glycosyl hydrolase family 6
Clocl_1570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Clocl_1572	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Clocl_1573	COG1027	Aspartate ammonia-lyase
Clocl_1574	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Clocl_1575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Clocl_1580	COG3775	system Galactitol-specific IIC component
Clocl_1582	COG1116	anion transmembrane transporter activity
Clocl_1583	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_1584	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Clocl_1604	COG3436	PFAM IS66 Orf2 family protein
Clocl_1616	COG3328	transposase activity
Clocl_1619	COG3436	PFAM IS66 Orf2 family protein
Clocl_1620	COG2963	transposase activity
Clocl_1639	COG2963	transposase activity
Clocl_1640	COG3436	PFAM IS66 Orf2 family protein
Clocl_1655	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Clocl_1664	COG3583	domain protein
Clocl_1664	COG3584	3D domain protein
Clocl_1665	COG2137	regulation of response to DNA damage stimulus
Clocl_1667	COG1971	Probably functions as a manganese efflux pump
Clocl_1676	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Clocl_1686	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Clocl_1687	COG2226	methyltransferase
Clocl_1692	COG3344	reverse transcriptase
Clocl_1695	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Clocl_1696	COG0732	type I restriction modification DNA specificity domain
Clocl_1698	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Clocl_1704	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Clocl_1707	COG0573	inorganic phosphate transmembrane transporter activity
Clocl_1708	COG0581	inorganic phosphate transmembrane transporter activity
Clocl_1709	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Clocl_1710	COG0704	Plays a role in the regulation of phosphate uptake
Clocl_1711	COG0745	RESPONSE REGULATOR receiver
Clocl_1712	COG5002	protein histidine kinase activity
Clocl_1717	COG1395	domain, Protein
Clocl_1719	COG1022	Amp-dependent synthetase and ligase
Clocl_1720	COG0295	cytidine deaminase activity
Clocl_1721	COG1079	Belongs to the binding-protein-dependent transport system permease family
Clocl_1722	COG4603	Belongs to the binding-protein-dependent transport system permease family
Clocl_1723	COG3845	ABC transporter
Clocl_1724	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Clocl_1725	COG1328	CTP reductase activity
Clocl_1726	COG1744	ABC transporter substrate-binding protein PnrA-like
Clocl_1735	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Clocl_1740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Clocl_1742	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Clocl_1743	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Clocl_1744	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Clocl_1745	COG1923	regulation of RNA biosynthetic process
Clocl_1746	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Clocl_1747	COG1388	LysM domain
Clocl_1747	COG3942	CHAP domain
Clocl_1752	COG1595	DNA-templated transcription, initiation
Clocl_1758	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Clocl_1759	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Clocl_1760	COG0228	four-way junction DNA binding
Clocl_1761	COG1837	Belongs to the UPF0109 family
Clocl_1762	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Clocl_1763	COG0336	Belongs to the RNA methyltransferase TrmD family
Clocl_1769	COG0534	Mate efflux family protein
Clocl_1771	COG0107	imidazoleglycerol-phosphate synthase activity
Clocl_1776	COG0077	Prephenate dehydratase
Clocl_1776	COG1605	Chorismate mutase
Clocl_1779	COG3290	protein histidine kinase activity
Clocl_1779	COG0840	transmembrane signaling receptor activity
Clocl_1780	COG2720	vancomycin resistance protein
Clocl_1787	COG0113	porphobilinogen synthase activity
Clocl_1788	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Clocl_1790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Clocl_1791	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Clocl_1795	COG5520	Belongs to the glycosyl hydrolase 30 family
Clocl_1796	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Clocl_1797	COG4974	Belongs to the 'phage' integrase family
Clocl_1799	COG3266	domain, Protein
Clocl_1799	COG2911	Protein conserved in bacteria
Clocl_1799	COG1361	Conserved repeat domain
Clocl_1802	COG2188	Transcriptional regulator
Clocl_1803	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Clocl_1804	COG0436	Aminotransferase
Clocl_1806	COG4733	cellulase activity
Clocl_1806	COG4447	cellulose binding
Clocl_1807	COG2003	Belongs to the UPF0758 family
Clocl_1808	COG0792	nuclease activity
Clocl_1809	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Clocl_1811	COG2273	Hydrolase Family 16
Clocl_1812	COG1609	Transcriptional regulator
Clocl_1813	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Clocl_1816	COG0335	large ribosomal subunit rRNA binding
Clocl_1819	COG2214	Heat shock protein DnaJ domain protein
Clocl_1820	COG0443	Heat shock 70 kDa protein
Clocl_1821	COG0840	transmembrane signaling receptor activity
Clocl_1824	COG4124	Belongs to the glycosyl hydrolase 26 family
Clocl_1826	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Clocl_1829	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Clocl_1831	COG1316	TRANSCRIPTIONal
Clocl_1832	COG1362	aminopeptidase activity
Clocl_1833	COG2199	diguanylate cyclase activity
Clocl_1833	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Clocl_1835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Clocl_1836	COG0482	sulfurtransferase activity
Clocl_1837	COG0822	iron-sulfur transferase activity
Clocl_1839	COG1959	2 iron, 2 sulfur cluster binding
Clocl_1842	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Clocl_1843	COG0105	UTP biosynthetic process
Clocl_1844	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Clocl_1845	COG0539	negative regulation of cytoplasmic translation
Clocl_1845	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Clocl_1848	COG4401	Chorismate mutase type I
Clocl_1852	COG2081	HI0933 family
Clocl_1853	COG0406	alpha-ribazole phosphatase activity
Clocl_1858	COG0318	PFAM AMP-dependent synthetase and ligase
Clocl_1859	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Clocl_1860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Clocl_1861	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Clocl_1862	COG4305	rare lipoprotein A
Clocl_1863	COG4733	cellulase activity
Clocl_1864	COG4447	cellulose binding
Clocl_1864	COG4733	cellulase activity
Clocl_1866	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Clocl_1869	COG3507	Belongs to the glycosyl hydrolase 43 family
Clocl_1870	COG1346	cytolysis
Clocl_1877	COG1595	DNA-templated transcription, initiation
Clocl_1878	COG1073	alpha beta
Clocl_1880	COG1131	(ABC) transporter
Clocl_1888	COG1297	OPT oligopeptide transporter protein
Clocl_1889	COG2195	Cleaves the N-terminal amino acid of tripeptides
Clocl_1890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Clocl_1891	COG1811	Na channel or pump
Clocl_1892	COG3033	Beta-eliminating lyase
Clocl_1900	COG1176	ABC-type spermidine putrescine transport system, permease component I
Clocl_1901	COG3842	ATPase activity
Clocl_1908	COG0582	viral genome integration into host DNA
Clocl_1915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Clocl_1929	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Clocl_1936	COG1191	sigma factor activity
Clocl_1938	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Clocl_1939	COG1776	CheC inhibitor of MCP methylation
Clocl_1940	COG0835	chemotaxis
Clocl_1941	COG2198	Histidine kinase
Clocl_1941	COG0643	Histidine kinase
Clocl_1942	COG2201	protein-glutamate methylesterase activity
Clocl_1945	COG1419	protein localization to endoplasmic reticulum
Clocl_1946	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Clocl_1947	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Clocl_1948	COG1684	flagellar biosynthetic protein fliR
Clocl_1949	COG1987	bacterial-type flagellum assembly
Clocl_1950	COG1338	Plays a role in the flagellum-specific transport system
Clocl_1952	COG2201	protein-glutamate methylesterase activity
Clocl_1953	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Clocl_1953	COG1776	CheC inhibitor of MCP methylation
Clocl_1954	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Clocl_1959	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Clocl_1964	COG1157	protein secretion by the type III secretion system
Clocl_1965	COG1317	bacterial-type flagellum organization
Clocl_1966	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Clocl_1968	COG1677	Flagellar hook-basal body complex protein FliE
Clocl_1970	COG1815	bacterial-type flagellum-dependent cell motility
Clocl_1971	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Clocl_1972	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Clocl_1973	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Clocl_1973	COG0758	DNA mediated transformation
Clocl_1974	COG0606	chelatase, subunit chli
Clocl_1976	COG0295	cytidine deaminase activity
Clocl_1978	COG1361	Conserved repeat domain
Clocl_1981	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clocl_1981	COG4447	cellulose binding
Clocl_1985	COG3263	regulation of cellular component size
Clocl_1989	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Clocl_1990	COG0588	phosphoglycerate mutase activity
Clocl_1998	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Clocl_2004	COG1410	methionine synthase
Clocl_2004	COG0646	methionine synthase
Clocl_2010	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Clocl_2011	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Clocl_2012	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Clocl_2014	COG2302	S4 RNA-binding domain
Clocl_2016	COG1799	cell septum assembly
Clocl_2017	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Clocl_2019	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Clocl_2020	COG0366	Alpha amylase catalytic
Clocl_2021	COG0564	pseudouridine synthase activity
Clocl_2026	COG0745	RESPONSE REGULATOR receiver
Clocl_2028	COG2201	protein-glutamate methylesterase activity
Clocl_2030	COG0835	chemotaxis
Clocl_2031	COG2198	Histidine kinase
Clocl_2031	COG0643	Histidine kinase
Clocl_2032	COG2201	protein-glutamate methylesterase activity
Clocl_2033	COG0745	RESPONSE REGULATOR receiver
Clocl_2034	COG0750	zinc metalloprotease
Clocl_2035	COG0497	DNA recombination
Clocl_2036	COG1438	arginine binding
Clocl_2037	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Clocl_2040	COG1472	Belongs to the glycosyl hydrolase 3 family
Clocl_2042	COG1686	Belongs to the peptidase S11 family
Clocl_2044	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Clocl_2045	COG1191	sigma factor activity
Clocl_2050	COG1136	(ABC) transporter
Clocl_2051	COG3850	Histidine kinase
Clocl_2051	COG5002	protein histidine kinase activity
Clocl_2052	COG0745	RESPONSE REGULATOR receiver
Clocl_2055	COG5002	protein histidine kinase activity
Clocl_2057	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Clocl_2058	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Clocl_2062	COG1722	exodeoxyribonuclease VII activity
Clocl_2063	COG1570	exodeoxyribonuclease VII activity
Clocl_2064	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Clocl_2067	COG1302	Protein conserved in bacteria
Clocl_2075	COG3854	ATPases associated with a variety of cellular activities
Clocl_2076	COG2233	PERMEase
Clocl_2077	COG1191	sigma factor activity
Clocl_2080	COG1748	Saccharopine dehydrogenase
Clocl_2085	COG0395	ABC-type sugar transport system, permease component
Clocl_2086	COG4209	transmembrane transport
Clocl_2089	COG1132	(ABC) transporter
Clocl_2095	COG0534	Mate efflux family protein
Clocl_2098	COG2755	lipolytic protein G-D-S-L family
Clocl_2099	COG1191	sigma factor activity
Clocl_2100	COG0584	glycerophosphoryl diester phosphodiesterase
Clocl_2108	COG1361	Conserved repeat domain
Clocl_2110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Clocl_2118	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Clocl_2119	COG0358	DNA primase activity
Clocl_2120	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Clocl_2124	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Clocl_2125	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Clocl_2126	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Clocl_2127	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Clocl_2127	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Clocl_2128	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Clocl_2129	COG1418	mRNA catabolic process
Clocl_2130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Clocl_2132	COG0564	pseudouridine synthase activity
Clocl_2133	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Clocl_2134	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Clocl_2135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_2136	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_2138	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Clocl_2139	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Clocl_2140	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Clocl_2143	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_2148	COG0747	negative chemotaxis
Clocl_2149	COG1496	oxidoreductase activity
Clocl_2154	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Clocl_2156	COG0517	IMP dehydrogenase activity
Clocl_2156	COG0516	GMP reductase activity
Clocl_2157	COG1028	Short-chain dehydrogenase reductase Sdr
Clocl_2159	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Clocl_2159	COG0723	plastoquinol--plastocyanin reductase activity
Clocl_2160	COG0617	tRNA 3'-terminal CCA addition
Clocl_2181	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Clocl_2182	COG1873	PFAM PRC-barrel domain
Clocl_2183	COG1191	sigma factor activity
Clocl_2184	COG1191	sigma factor activity
Clocl_2187	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Clocl_2189	COG3856	small basic protein
Clocl_2190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Clocl_2192	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Clocl_2193	COG3442	glutamine amidotransferase
Clocl_2197	COG0442	prolyl-tRNA aminoacylation
Clocl_2199	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Clocl_2201	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Clocl_2204	COG1959	2 iron, 2 sulfur cluster binding
Clocl_2205	COG1959	2 iron, 2 sulfur cluster binding
Clocl_2206	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Clocl_2207	COG2608	mercury ion transmembrane transporter activity
Clocl_2208	COG2217	Heavy metal translocating P-type atpase
Clocl_2210	COG2205	protein histidine kinase activity
Clocl_2211	COG0745	RESPONSE REGULATOR receiver
Clocl_2218	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Clocl_2221	COG3458	cephalosporin-C deacetylase activity
Clocl_2222	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Clocl_2223	COG1472	Belongs to the glycosyl hydrolase 3 family
Clocl_2225	COG4733	cellulase activity
Clocl_2225	COG4447	cellulose binding
Clocl_2227	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Clocl_2234	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Clocl_2235	COG3328	transposase activity
Clocl_2241	COG3314	Sporulation integral membrane protein YlbJ
Clocl_2243	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Clocl_2244	COG0742	ribosomal rna small subunit methyltransferase
Clocl_2245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Clocl_2246	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Clocl_2250	COG0849	cell division
Clocl_2251	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Clocl_2252	COG0297	glycogen (starch) synthase activity
Clocl_2253	COG2199	diguanylate cyclase activity
Clocl_2253	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Clocl_2254	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Clocl_2255	COG3850	Histidine kinase
Clocl_2255	COG5002	protein histidine kinase activity
Clocl_2256	COG0745	RESPONSE REGULATOR receiver
Clocl_2260	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Clocl_2262	COG0789	Transcriptional regulator
Clocl_2263	COG2135	peptidase activity
Clocl_2265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Clocl_2274	COG0765	amino acid transport
Clocl_2275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Clocl_2279	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Clocl_2282	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Clocl_2286	COG1323	Belongs to the UPF0348 family
Clocl_2287	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Clocl_2289	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Clocl_2290	COG0662	Cupin 2, conserved barrel domain protein
Clocl_2292	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Clocl_2294	COG3266	domain, Protein
Clocl_2294	COG1361	Conserved repeat domain
Clocl_2294	COG2911	Protein conserved in bacteria
Clocl_2295	COG0655	NAD(P)H dehydrogenase (quinone) activity
Clocl_2296	COG2217	Heavy metal translocating P-type atpase
Clocl_2299	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_2300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clocl_2302	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Clocl_2303	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Clocl_2304	COG5012	cobalamin binding
Clocl_2306	COG0778	Nitroreductase
Clocl_2307	COG1433	Dinitrogenase iron-molybdenum cofactor
Clocl_2307	COG0535	radical SAM domain protein
Clocl_2311	COG3328	transposase activity
Clocl_2313	COG4372	Transposase
Clocl_2317	COG2963	transposase activity
Clocl_2329	COG3436	PFAM IS66 Orf2 family protein
Clocl_2331	COG4372	Transposase
Clocl_2332	COG3436	PFAM IS66 Orf2 family protein
Clocl_2333	COG2963	transposase activity
Clocl_2340	COG3436	PFAM IS66 Orf2 family protein
Clocl_2341	COG2963	transposase activity
Clocl_2349	COG4372	Transposase
Clocl_2350	COG3436	PFAM IS66 Orf2 family protein
Clocl_2351	COG2963	transposase activity
Clocl_2372	COG2359	stage V sporulation protein S
Clocl_2375	COG0571	ribonuclease III activity
Clocl_2376	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Clocl_2377	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Clocl_2378	COG1028	Short-chain dehydrogenase reductase Sdr
Clocl_2379	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Clocl_2380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Clocl_2381	COG0416	fatty acid biosynthetic process
Clocl_2382	COG2030	dehydratase
Clocl_2383	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Clocl_2384	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Clocl_2388	COG0588	phosphoglycerate mutase activity
Clocl_2389	COG0167	dihydroorotate dehydrogenase activity
Clocl_2390	COG0543	2 iron, 2 sulfur cluster binding
Clocl_2391	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Clocl_2393	COG0284	orotidine-5'-phosphate decarboxylase activity
Clocl_2394	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Clocl_2395	COG0540	Belongs to the ATCase OTCase family
Clocl_2397	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Clocl_2402	COG1862	Preprotein translocase
Clocl_2403	COG0343	queuine tRNA-ribosyltransferase activity
Clocl_2404	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Clocl_2405	COG2385	sporulation resulting in formation of a cellular spore
Clocl_2405	COG2247	cell wall binding repeat
Clocl_2406	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Clocl_2407	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Clocl_2409	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Clocl_2411	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Clocl_2413	COG0488	(ABC) transporter
Clocl_2416	COG1216	Glycosyl transferase, family 2
Clocl_2419	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Clocl_2420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Clocl_2421	COG0772	Belongs to the SEDS family
Clocl_2422	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Clocl_2423	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Clocl_2424	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Clocl_2425	COG0768	penicillin binding
Clocl_2427	COG0275	rRNA processing
Clocl_2428	COG2001	Belongs to the MraZ family
Clocl_2429	COG0772	Belongs to the SEDS family
Clocl_2431	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Clocl_2432	COG0612	Peptidase, M16
Clocl_2433	COG0612	Peptidase, M16
Clocl_2434	COG2199	diguanylate cyclase activity
Clocl_2437	COG3507	Belongs to the glycosyl hydrolase 43 family
Clocl_2440	COG1070	Carbohydrate kinase
Clocl_2440	COG4806	L-rhamnose isomerase
Clocl_2441	COG2382	esterase
Clocl_2441	COG3507	Belongs to the glycosyl hydrolase 43 family
Clocl_2441	COG3693	PFAM glycoside hydrolase, family 10
Clocl_2445	COG3534	alpha-L-arabinofuranosidase
Clocl_2447	COG2382	esterase
Clocl_2447	COG3507	Belongs to the glycosyl hydrolase 43 family
Clocl_2447	COG3693	PFAM glycoside hydrolase, family 10
Clocl_2449	COG0196	riboflavin kinase activity
Clocl_2450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Clocl_2451	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Clocl_2452	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Clocl_2453	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Clocl_2455	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Clocl_2456	COG0195	Participates in both transcription termination and antitermination
Clocl_2457	COG0779	Required for maturation of 30S ribosomal subunits
Clocl_2458	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Clocl_2460	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Clocl_2461	COG4589	Belongs to the CDS family
Clocl_2464	COG0233	cytoplasmic translational termination
Clocl_2465	COG0528	UMP kinase activity
Clocl_2466	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Clocl_2467	COG0052	Belongs to the universal ribosomal protein uS2 family
Clocl_2468	COG1217	gtp-binding protein TYPA
Clocl_2469	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Clocl_2470	COG4122	O-methyltransferase activity
Clocl_2471	COG0826	peptidase U32
Clocl_2472	COG0768	penicillin binding
Clocl_2475	COG0628	permease
Clocl_2479	COG0813	purine-nucleoside phosphorylase activity
Clocl_2480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Clocl_2482	COG1079	Belongs to the binding-protein-dependent transport system permease family
Clocl_2483	COG4603	Belongs to the binding-protein-dependent transport system permease family
Clocl_2484	COG3845	ABC transporter
Clocl_2486	COG2188	Transcriptional regulator
Clocl_2495	COG3328	transposase activity
Clocl_2506	COG1193	negative regulation of DNA recombination
Clocl_2508	COG0860	N-Acetylmuramoyl-L-alanine amidase
Clocl_2510	COG1653	transport
Clocl_2513	COG0395	ABC-type sugar transport system, permease component
Clocl_2514	COG1175	transmembrane transport
Clocl_2516	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Clocl_2517	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Clocl_2518	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Clocl_2519	COG1160	GTP binding
Clocl_2520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Clocl_2521	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Clocl_2523	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Clocl_2524	COG0280	phosphate acetyltransferase
Clocl_2525	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Clocl_2527	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Clocl_2529	COG1595	DNA-templated transcription, initiation
Clocl_2531	COG3328	transposase activity
Clocl_2532	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Clocl_2534	COG0860	N-Acetylmuramoyl-L-alanine amidase
Clocl_2536	COG0268	Binds directly to 16S ribosomal RNA
Clocl_2538	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Clocl_2539	COG1388	LysM domain
Clocl_2539	COG0791	NLP P60 protein
Clocl_2542	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Clocl_2543	COG0352	thiamine-phosphate diphosphorylase activity
Clocl_2546	COG2022	thiamine diphosphate biosynthetic process
Clocl_2547	COG2022	thiamine diphosphate biosynthetic process
Clocl_2547	COG2104	thiamine diphosphate biosynthetic process
Clocl_2548	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Clocl_2553	COG1361	Conserved repeat domain
Clocl_2553	COG2911	Protein conserved in bacteria
Clocl_2553	COG3266	domain, Protein
Clocl_2554	COG4485	Bacterial membrane protein, YfhO
Clocl_2555	COG0463	Glycosyl transferase, family 2
Clocl_2557	COG1309	transcriptional regulator
Clocl_2560	COG2204	response regulator
Clocl_2561	COG1293	RNA-binding protein homologous to eukaryotic snRNP
Clocl_2562	COG0436	Aminotransferase
Clocl_2563	COG1564	THIamine pyrophosphokinase
Clocl_2564	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Clocl_2565	COG1162	GTPase activity
Clocl_2566	COG0515	serine threonine protein kinase
Clocl_2566	COG2815	serine threonine protein kinase
Clocl_2567	COG0631	protein serine/threonine phosphatase activity
Clocl_2568	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Clocl_2569	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Clocl_2569	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Clocl_2570	COG2738	Putative neutral zinc metallopeptidase
Clocl_2572	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Clocl_2573	COG0242	peptide deformylase activity
Clocl_2574	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Clocl_2577	COG1477	protein flavinylation
Clocl_2582	COG0393	Putative heavy-metal-binding
Clocl_2585	COG0367	asparagine synthase
Clocl_2589	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Clocl_2590	COG0583	DNA-binding transcription factor activity
Clocl_2592	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Clocl_2600	COG0024	Methionine aminopeptidase
Clocl_2603	COG3328	transposase activity
Clocl_2605	COG0285	dihydrofolate synthase activity
Clocl_2606	COG0653	protein targeting
Clocl_2609	COG4496	protein, YerC YecD
Clocl_2610	COG0617	tRNA 3'-terminal CCA addition
Clocl_2625	COG1191	sigma factor activity
Clocl_2626	COG0135	phosphoribosylanthranilate isomerase activity
Clocl_2627	COG0134	indole-3-glycerol-phosphate synthase activity
Clocl_2628	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Clocl_2629	COG0512	Glutamine amidotransferase of anthranilate synthase
Clocl_2629	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Clocl_2631	COG0513	Belongs to the DEAD box helicase family
Clocl_2634	COG0012	GTP binding
Clocl_2636	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Clocl_2637	COG2199	diguanylate cyclase activity
Clocl_2637	COG2203	Gaf domain
Clocl_2639	COG1486	melibiose metabolic process
Clocl_2641	COG0697	spore germination
Clocl_2644	COG0237	dephospho-CoA kinase activity
Clocl_2645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Clocl_2645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Clocl_2651	COG0552	protein localization to endoplasmic reticulum
Clocl_2655	COG1136	(ABC) transporter
Clocl_2663	COG3321	synthase
Clocl_2663	COG1028	Short-chain dehydrogenase reductase Sdr
Clocl_2663	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Clocl_2663	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Clocl_2663	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Clocl_2683	COG3436	PFAM IS66 Orf2 family protein
Clocl_2684	COG2963	transposase activity
Clocl_2687	COG4372	Transposase
Clocl_2688	COG3436	PFAM IS66 Orf2 family protein
Clocl_2695	COG4372	Transposase
Clocl_2696	COG3436	PFAM IS66 Orf2 family protein
Clocl_2699	COG3328	transposase activity
Clocl_2707	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Clocl_2710	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Clocl_2711	COG5012	cobalamin binding
Clocl_2719	COG1013	pyruvate-flavodoxin oxidoreductase activity
Clocl_2720	COG0674	pyruvate-flavodoxin oxidoreductase activity
Clocl_2721	COG1144	Oxidoreductase
Clocl_2724	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Clocl_2725	COG2011	ABC-type metal ion transport system permease component
Clocl_2726	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Clocl_2727	COG1464	Belongs to the NlpA lipoprotein family
Clocl_2730	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Clocl_2731	COG1606	tRNA processing
Clocl_2732	COG1959	2 iron, 2 sulfur cluster binding
Clocl_2738	COG0789	Transcriptional regulator
Clocl_2743	COG3328	transposase activity
Clocl_2745	COG3693	PFAM glycoside hydrolase, family 10
Clocl_2746	COG2382	esterase
Clocl_2746	COG3507	Belongs to the glycosyl hydrolase 43 family
Clocl_2746	COG3693	PFAM glycoside hydrolase, family 10
Clocl_2747	COG5183	chlorophyll binding
Clocl_2747	COG2133	pyrroloquinoline quinone binding
Clocl_2748	COG1191	sigma factor activity
Clocl_2753	COG2323	membrane
Clocl_2755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Clocl_2755	COG0574	Belongs to the PEP-utilizing enzyme family
Clocl_2756	COG0423	glycine-tRNA ligase activity
Clocl_2757	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Clocl_2758	COG1758	RNA polymerase activity
Clocl_2759	COG0194	GDP metabolic process
Clocl_2760	COG2052	Domain of unknown function (DUF370)
Clocl_2761	COG1561	YicC-like family, N-terminal region
Clocl_2763	COG2273	Hydrolase Family 16
Clocl_2764	COG2201	protein-glutamate methylesterase activity
Clocl_2765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Clocl_2766	COG2264	protein methyltransferase activity
Clocl_2767	COG0484	heat shock protein binding
Clocl_2768	COG0443	Heat shock 70 kDa protein
Clocl_2769	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Clocl_2770	COG1420	regulation of RNA biosynthetic process
Clocl_2771	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Clocl_2772	COG0481	GTPase activity
Clocl_2779	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Clocl_2780	COG0124	histidyl-tRNA synthetase
Clocl_2781	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Clocl_2782	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Clocl_2783	COG1490	D-aminoacyl-tRNA deacylase activity
Clocl_2784	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Clocl_2785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Clocl_2786	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Clocl_2786	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Clocl_2790	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Clocl_2791	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Clocl_2792	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Clocl_2797	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Clocl_2798	COG1191	sigma factor activity
Clocl_2814	COG0438	transferase activity, transferring glycosyl groups
Clocl_2815	COG1215	transferase activity, transferring glycosyl groups
Clocl_2822	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Clocl_2823	COG3328	transposase activity
Clocl_2826	COG1216	Glycosyl transferase, family 2
Clocl_2828	COG0438	transferase activity, transferring glycosyl groups
Clocl_2831	COG1091	dTDP-4-dehydrorhamnose reductase activity
Clocl_2833	COG0489	protein tyrosine kinase activity
Clocl_2835	COG4464	protein tyrosine phosphatase activity
Clocl_2836	COG2911	Protein conserved in bacteria
Clocl_2836	COG3266	domain, Protein
Clocl_2836	COG1361	Conserved repeat domain
Clocl_2837	COG0537	adenosine 5'-monophosphoramidase activity
Clocl_2838	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Clocl_2839	COG0628	permease
Clocl_2843	COG4447	cellulose binding
Clocl_2844	COG1191	sigma factor activity
Clocl_2856	COG2172	sigma factor antagonist activity
Clocl_2857	COG1032	radical SAM domain protein
Clocl_2858	COG1686	Belongs to the peptidase S11 family
Clocl_2864	COG0569	domain protein
Clocl_2865	COG2323	membrane
Clocl_2871	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Clocl_2872	COG2207	Transcriptional regulator
Clocl_2872	COG4753	response regulator
Clocl_2877	COG1187	pseudouridine synthase activity
Clocl_2878	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Clocl_2878	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Clocl_2879	COG0840	transmembrane signaling receptor activity
Clocl_2880	COG1234	tRNA 3'-trailer cleavage
Clocl_2883	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Clocl_2884	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
Clocl_2886	COG0527	aspartate kinase activity
Clocl_2887	COG0460	homoserine dehydrogenase
Clocl_2888	COG4492	Belongs to the UPF0735 family
Clocl_2889	COG2199	diguanylate cyclase activity
Clocl_2889	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Clocl_2890	COG0673	inositol 2-dehydrogenase activity
Clocl_2891	COG2201	protein-glutamate methylesterase activity
Clocl_2893	COG1752	Esterase of the alpha-beta hydrolase superfamily
Clocl_2894	COG0631	protein serine/threonine phosphatase activity
Clocl_2896	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Clocl_2902	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Clocl_2904	COG2214	Heat shock protein DnaJ domain protein
Clocl_2905	COG0443	Heat shock 70 kDa protein
Clocl_2906	COG1489	DNA binding
Clocl_2908	COG0778	Nitroreductase
Clocl_2909	COG0778	Nitroreductase
Clocl_2919	COG1592	Rubrerythrin
Clocl_2938	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Clocl_2944	COG2911	Protein conserved in bacteria
Clocl_2944	COG1361	Conserved repeat domain
Clocl_2944	COG3266	domain, Protein
Clocl_2962	COG3328	transposase activity
Clocl_2964	COG3328	transposase activity
Clocl_2971	COG0701	Predicted permease
Clocl_2973	COG0798	PFAM Bile acid sodium symporter
Clocl_2974	COG0640	Transcriptional regulator
Clocl_2979	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Clocl_2980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Clocl_2981	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Clocl_2983	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Clocl_2985	COG3885	ferrous iron binding
Clocl_2985	COG2078	PFAM AMMECR1 domain protein
Clocl_2988	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Clocl_2988	COG1918	ferrous iron import across plasma membrane
Clocl_2992	COG3870	Protein conserved in bacteria
Clocl_2993	COG1686	Belongs to the peptidase S11 family
Clocl_3004	COG1904	glucuronate isomerase
Clocl_3006	COG1361	Conserved repeat domain
Clocl_3010	COG0402	S-adenosylhomocysteine deaminase activity
Clocl_3011	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Clocl_3014	COG2719	SpoVR family
Clocl_3015	COG2718	Belongs to the UPF0229 family
Clocl_3016	COG2766	serine protein kinase
Clocl_3021	COG0730	response to heat
Clocl_3022	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Clocl_3024	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Clocl_3028	COG3459	Glycosyltransferase 36 associated
Clocl_3029	COG3291	Pkd domain containing protein
Clocl_3030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Clocl_3031	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Clocl_3032	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Clocl_3033	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Clocl_3035	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Clocl_3036	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Clocl_3038	COG4447	cellulose binding
Clocl_3038	COG4733	cellulase activity
Clocl_3040	COG1555	photosystem II stabilization
Clocl_3042	COG1686	Belongs to the peptidase S11 family
Clocl_3044	COG3328	transposase activity
Clocl_3050	COG4604	ABC transporter, ATP-binding protein
Clocl_3052	COG3328	transposase activity
Clocl_3053	COG0799	negative regulation of ribosome biogenesis
Clocl_3055	COG1713	HD superfamily hydrolase involved in NAD metabolism
Clocl_3056	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Clocl_3058	COG3940	Belongs to the glycosyl hydrolase 43 family
Clocl_3066	COG0151	Belongs to the GarS family
Clocl_3067	COG0138	bifunctional purine biosynthesis protein purh
Clocl_3068	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Clocl_3069	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Clocl_3070	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Clocl_3071	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Clocl_3072	COG2252	PERMEase
Clocl_3083	COG0519	Catalyzes the synthesis of GMP from XMP
Clocl_3085	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Clocl_3086	COG1691	(AIR) carboxylase
Clocl_3089	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Clocl_3092	COG0561	phosphatase activity
Clocl_3093	COG0436	Aminotransferase
Clocl_3094	COG1522	sequence-specific DNA binding
Clocl_3096	COG3118	belongs to the thioredoxin family
Clocl_3097	COG1937	Protein conserved in bacteria
Clocl_3101	COG1379	DNA repair
Clocl_3102	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Clocl_3104	COG1924	4 iron, 4 sulfur cluster binding
Clocl_3108	COG0191	fructose-bisphosphate aldolase activity
Clocl_3109	COG0205	6-phosphofructokinase activity
Clocl_3111	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Clocl_3113	COG5183	chlorophyll binding
Clocl_3113	COG2133	pyrroloquinoline quinone binding
Clocl_3125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Clocl_3127	COG0542	response to heat
Clocl_3129	COG0556	nucleotide-excision repair
Clocl_3132	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clocl_3132	COG4124	Belongs to the glycosyl hydrolase 26 family
Clocl_3135	COG5002	protein histidine kinase activity
Clocl_3136	COG0745	RESPONSE REGULATOR receiver
Clocl_3140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Clocl_3147	COG4447	cellulose binding
Clocl_3150	COG1032	radical SAM domain protein
Clocl_3164	COG2963	transposase activity
Clocl_3165	COG3436	PFAM IS66 Orf2 family protein
Clocl_3172	COG4372	Transposase
Clocl_3173	COG3436	PFAM IS66 Orf2 family protein
Clocl_3174	COG2963	transposase activity
Clocl_3175	COG3328	transposase activity
Clocl_3179	COG1136	(ABC) transporter
Clocl_3184	COG2207	Transcriptional regulator
Clocl_3184	COG3708	Transcriptional regulator
Clocl_3203	COG3436	PFAM IS66 Orf2 family protein
Clocl_3204	COG2963	transposase activity
Clocl_3210	COG2032	superoxide dismutase activity
Clocl_3212	COG0187	DNA topoisomerase II activity
Clocl_3216	COG2340	Cysteine-rich secretory protein family
Clocl_3223	COG0697	spore germination
Clocl_3224	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Clocl_3225	COG1268	BioY protein
Clocl_3226	COG0778	Nitroreductase
Clocl_3227	COG1028	Short-chain dehydrogenase reductase Sdr
Clocl_3234	COG2226	methyltransferase
Clocl_3238	COG1331	Highly conserved protein containing a thioredoxin domain
Clocl_3240	COG1199	ATP-dependent helicase activity
Clocl_3242	COG2217	Heavy metal translocating P-type atpase
Clocl_3244	COG2723	6-phospho-beta-galactosidase activity
Clocl_3247	COG1649	PFAM Uncharacterised BCR, COG1649
Clocl_3252	COG0432	Pfam Uncharacterised protein family UPF0047
Clocl_3253	COG4733	cellulase activity
Clocl_3253	COG4447	cellulose binding
Clocl_3255	COG4447	cellulose binding
Clocl_3255	COG4733	cellulase activity
Clocl_3262	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Clocl_3270	COG1573	uracil-dna glycosylase
Clocl_3271	COG0602	queuosine metabolic process
Clocl_3272	COG0720	synthase
Clocl_3273	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Clocl_3277	COG1316	TRANSCRIPTIONal
Clocl_3278	COG0436	Aminotransferase
Clocl_3279	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Clocl_3283	COG0463	Glycosyl transferase, family 2
Clocl_3289	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Clocl_3296	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Clocl_3298	COG0116	Belongs to the methyltransferase superfamily
Clocl_3303	COG1361	Conserved repeat domain
Clocl_3304	COG1361	Conserved repeat domain
Clocl_3304	COG2911	Protein conserved in bacteria
Clocl_3304	COG3266	domain, Protein
Clocl_3305	COG3266	domain, Protein
Clocl_3305	COG1361	Conserved repeat domain
Clocl_3305	COG2911	Protein conserved in bacteria
Clocl_3307	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Clocl_3308	COG0768	penicillin binding
Clocl_3311	COG1716	ATPase activity
Clocl_3313	COG0457	Tetratricopeptide repeat
Clocl_3313	COG0705	Rhomboid family
Clocl_3318	COG1131	(ABC) transporter
Clocl_3320	COG5002	protein histidine kinase activity
Clocl_3321	COG0745	RESPONSE REGULATOR receiver
Clocl_3322	COG1132	(ABC) transporter
Clocl_3323	COG1671	Belongs to the UPF0178 family
Clocl_3325	COG0039	L-malate dehydrogenase activity
Clocl_3326	COG0281	malic enzyme
Clocl_3327	COG2755	lipolytic protein G-D-S-L family
Clocl_3327	COG3401	FG-GAP repeat protein
Clocl_3331	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Clocl_3332	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Clocl_3333	COG2267	carboxylic ester hydrolase activity
Clocl_3334	COG1361	Conserved repeat domain
Clocl_3339	COG1595	DNA-templated transcription, initiation
Clocl_3341	COG1132	(ABC) transporter
Clocl_3343	COG1846	Transcriptional regulator
Clocl_3344	COG0372	Belongs to the citrate synthase family
Clocl_3346	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Clocl_3348	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Clocl_3349	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Clocl_3350	COG0561	phosphatase activity
Clocl_3352	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Clocl_3354	COG0840	transmembrane signaling receptor activity
Clocl_3359	COG1595	DNA-templated transcription, initiation
Clocl_3360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Clocl_3362	COG5002	protein histidine kinase activity
Clocl_3365	COG1968	undecaprenyl-diphosphatase activity
Clocl_3366	COG1392	Phosphate transport regulator
Clocl_3367	COG0306	phosphate transporter
Clocl_3368	COG4377	Putative membrane peptidase family (DUF2324)
Clocl_3382	COG1074	ATP-dependent DNA helicase activity
Clocl_3383	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Clocl_3391	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Clocl_3391	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Clocl_3393	COG1028	Short-chain dehydrogenase reductase Sdr
Clocl_3394	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Clocl_3395	COG2911	Protein conserved in bacteria
Clocl_3398	COG0840	transmembrane signaling receptor activity
Clocl_3402	COG0840	transmembrane signaling receptor activity
Clocl_3404	COG0493	'glutamate synthase
Clocl_3410	COG0463	Glycosyl transferase, family 2
Clocl_3411	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Clocl_3419	COG0175	sulfate reduction
Clocl_3420	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Clocl_3421	COG0626	cystathionine gamma-synthase activity
Clocl_3429	COG2378	regulation of single-species biofilm formation
Clocl_3432	COG3682	Transcriptional regulator
Clocl_3467	COG4584	PFAM Integrase catalytic
Clocl_3467	COG2390	Transcriptional regulator
Clocl_3484	COG2239	Acts as a magnesium transporter
Clocl_3487	COG0840	transmembrane signaling receptor activity
Clocl_3489	COG2207	Transcriptional regulator
Clocl_3489	COG3708	Transcriptional regulator
Clocl_3490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Clocl_3494	COG2409	Drug exporters of the RND superfamily
Clocl_3496	COG0717	Belongs to the dCTP deaminase family
Clocl_3503	COG1819	glycosyl
Clocl_3509	COG0840	transmembrane signaling receptor activity
Clocl_3515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Clocl_3521	COG1442	glycosyl transferase family 8
Clocl_3523	COG0351	phosphomethylpyrimidine kinase
Clocl_3523	COG0352	thiamine-phosphate diphosphorylase activity
Clocl_3524	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Clocl_3528	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Clocl_3536	COG1136	(ABC) transporter
Clocl_3537	COG2205	protein histidine kinase activity
Clocl_3553	COG2059	Chromate
Clocl_3556	COG1131	(ABC) transporter
Clocl_3560	COG2894	cell division
Clocl_3565	COG0822	iron-sulfur transferase activity
Clocl_3566	COG1342	Belongs to the UPF0251 family
Clocl_3568	COG3290	protein histidine kinase activity
Clocl_3569	COG3279	Response regulator of the LytR AlgR family
Clocl_3576	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Clocl_3579	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Clocl_3580	COG1492	cobalamin metabolic process
Clocl_3583	COG1797	cobyrinic acid a,c-diamide synthase activity
Clocl_3586	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Clocl_3587	COG0113	porphobilinogen synthase activity
Clocl_3589	COG0181	hydroxymethylbilane synthase activity
Clocl_3596	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Clocl_3597	COG1122	ATPase activity
Clocl_3598	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Clocl_3600	COG0310	cobalt ion transport
Clocl_3613	COG1595	DNA-templated transcription, initiation
Clocl_3615	COG3344	reverse transcriptase
Clocl_3619	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Clocl_3622	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Clocl_3623	COG0732	type I restriction modification DNA specificity domain
Clocl_3625	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Clocl_3637	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Clocl_3640	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Clocl_3641	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Clocl_3649	COG3344	reverse transcriptase
Clocl_3651	COG3344	reverse transcriptase
Clocl_3653	COG1595	DNA-templated transcription, initiation
Clocl_3656	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Clocl_3660	COG3409	Peptidoglycan-binding domain 1 protein
Clocl_3660	COG5632	N-Acetylmuramoyl-L-alanine amidase
Clocl_3678	COG1136	(ABC) transporter
Clocl_3680	COG2205	protein histidine kinase activity
Clocl_3681	COG0745	RESPONSE REGULATOR receiver
Clocl_3687	COG2963	transposase activity
Clocl_3689	COG5433	transposase activity
Clocl_3691	COG3344	reverse transcriptase
Clocl_3693	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Clocl_3694	COG2217	Heavy metal translocating P-type atpase
Clocl_3697	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Clocl_3701	COG5632	N-Acetylmuramoyl-L-alanine amidase
Clocl_3701	COG3409	Peptidoglycan-binding domain 1 protein
Clocl_3717	COG0740	serine-type endopeptidase activity
Clocl_3718	COG4695	Portal protein
Clocl_3719	COG1802	Transcriptional regulator
Clocl_3719	COG4626	Terminase
Clocl_3736	COG3617	BRO family, N-terminal domain
Clocl_3737	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Clocl_3737	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Clocl_3745	COG1595	DNA-templated transcription, initiation
Clocl_3754	COG1393	Belongs to the ArsC family
Clocl_3756	COG1595	DNA-templated transcription, initiation
Clocl_3758	COG1012	belongs to the aldehyde dehydrogenase family
Clocl_3759	COG1454	alcohol dehydrogenase
Clocl_3760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Clocl_3762	COG1401	restriction endodeoxyribonuclease activity
Clocl_3765	COG1126	abc transporter atp-binding protein
Clocl_3766	COG0765	amino acid transport
Clocl_3769	COG3655	Transcriptional regulator
Clocl_3774	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Clocl_3775	COG1126	abc transporter atp-binding protein
Clocl_3776	COG0765	amino acid transport
Clocl_3779	COG3328	transposase activity
Clocl_3783	COG1464	Belongs to the NlpA lipoprotein family
Clocl_3784	COG2011	ABC-type metal ion transport system permease component
Clocl_3785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Clocl_3794	COG3328	transposase activity
Clocl_3796	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Clocl_3797	COG1136	(ABC) transporter
Clocl_3801	COG1695	Transcriptional regulator
Clocl_3810	COG1797	cobyrinic acid a,c-diamide synthase activity
Clocl_3811	COG2226	methyltransferase
Clocl_3812	COG4260	virion core protein, lumpy skin disease virus
Clocl_3813	COG0739	heme binding
Clocl_3818	COG0577	efflux transmembrane transporter activity
Clocl_3820	COG1136	(ABC) transporter
Clocl_3824	COG2340	Cysteine-rich secretory protein family
Clocl_3832	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Clocl_3833	COG0372	Belongs to the citrate synthase family
Clocl_3834	COG1802	Transcriptional regulator
Clocl_3838	COG1067	ATP-dependent peptidase activity
Clocl_3840	COG1214	PFAM Peptidase M22, glycoprotease
Clocl_3841	COG0802	atpase or kinase
Clocl_3842	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Clocl_3845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Clocl_3852	COG3328	transposase activity
Clocl_3857	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Clocl_3858	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Clocl_3859	COG0101	tRNA pseudouridine synthase activity
Clocl_3860	COG1940	carbohydrate kinase activity
Clocl_3861	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Clocl_3862	COG1122	ATPase activity
Clocl_3863	COG2813	Specifically methylates the guanine in position
Clocl_3864	COG1122	ATPase activity
Clocl_3865	COG0203	ribosomal protein L17
Clocl_3866	COG0202	RNA polymerase activity
Clocl_3867	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Clocl_3869	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Clocl_3870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Clocl_3871	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Clocl_3874	COG0563	adenylate kinase activity
Clocl_3875	COG0201	protein transport
Clocl_3876	COG0200	Binds to the 23S rRNA
Clocl_3877	COG1841	ribosomal large subunit assembly
Clocl_3878	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Clocl_3879	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Clocl_3880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Clocl_3881	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Clocl_3882	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Clocl_3883	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Clocl_3884	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Clocl_3885	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Clocl_3886	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Clocl_3887	COG0255	Belongs to the universal ribosomal protein uL29 family
Clocl_3888	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Clocl_3889	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Clocl_3890	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Clocl_3891	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Clocl_3892	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Clocl_3893	COG0089	rRNA binding
Clocl_3894	COG0088	Forms part of the polypeptide exit tunnel
Clocl_3895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Clocl_3896	COG0051	transcription antitermination factor activity, RNA binding
Clocl_3897	COG2314	TM2 domain
Clocl_3902	COG2244	polysaccharide biosynthetic process
Clocl_3908	COG1191	sigma factor activity
Clocl_3910	COG1366	Belongs to the anti-sigma-factor antagonist family
Clocl_3911	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Clocl_3912	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Clocl_3914	COG3858	chitin binding
Clocl_3917	COG2273	Hydrolase Family 16
Clocl_3917	COG5297	Belongs to the glycosyl hydrolase family 6
Clocl_3918	COG0459	protein refolding
Clocl_3919	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Clocl_3920	COG2755	lipolytic protein G-D-S-L family
Clocl_3920	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clocl_3923	COG0107	imidazoleglycerol-phosphate synthase activity
Clocl_3924	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Clocl_3925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Clocl_3926	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Clocl_3927	COG0131	Imidazoleglycerol-phosphate dehydratase
Clocl_3928	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Clocl_3929	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Clocl_3930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Clocl_3931	COG0124	histidyl-tRNA synthetase
Clocl_3932	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clocl_3937	COG1309	transcriptional regulator
Clocl_3940	COG0210	DNA helicase
Clocl_3941	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Clocl_3942	COG0347	Belongs to the P(II) protein family
Clocl_3943	COG0004	ammonium transporteR
Clocl_3946	COG1215	transferase activity, transferring glycosyl groups
Clocl_3949	COG1266	CAAX protease self-immunity
Clocl_3953	COG2911	Protein conserved in bacteria
Clocl_3955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Clocl_3956	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Clocl_3961	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Clocl_3968	COG5297	Belongs to the glycosyl hydrolase family 6
Clocl_3969	COG0318	PFAM AMP-dependent synthetase and ligase
Clocl_3971	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Clocl_3978	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Clocl_3980	COG0215	cysteine-tRNA ligase activity
Clocl_3981	COG1045	serine acetyltransferase
Clocl_3989	COG1473	amidohydrolase
Clocl_3990	COG2155	Conserved Protein
Clocl_3994	COG0217	transcriptional regulatory protein
Clocl_3997	COG1739	Uncharacterized protein family UPF0029
Clocl_4000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Clocl_4002	COG0756	dUTP diphosphatase activity
Clocl_4003	COG0826	peptidase U32
Clocl_4004	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Clocl_4007	COG5297	Belongs to the glycosyl hydrolase family 6
Clocl_4008	COG4447	cellulose binding
Clocl_4009	COG1191	sigma factor activity
Clocl_4010	COG1983	PspC domain protein
Clocl_4013	COG0670	Belongs to the BI1 family
Clocl_4014	COG2703	oxygen carrier activity
Clocl_4016	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Clocl_4017	COG3584	3D domain protein
Clocl_4017	COG3583	domain protein
Clocl_4019	COG0084	hydrolase, TatD family'
Clocl_4020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Clocl_4020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Clocl_4021	COG0700	Nucleoside recognition
Clocl_4022	COG2715	membrane protein required for spore maturation
Clocl_4023	COG2002	toxin-antitoxin pair type II binding
Clocl_4024	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Clocl_4025	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Clocl_4027	COG1774	PSP1 C-terminal conserved region
Clocl_4029	COG1728	Protein conserved in bacteria
Clocl_4031	COG1982	Orn Lys Arg decarboxylase major
Clocl_4033	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Clocl_4036	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Clocl_4039	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Clocl_4039	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Clocl_4041	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Clocl_4042	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Clocl_4043	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Clocl_4048	COG1695	Transcriptional regulator
Clocl_4050	COG0840	transmembrane signaling receptor activity
Clocl_4052	COG0302	gtp cyclohydrolase
Clocl_4053	COG4214	carbohydrate transport
Clocl_4055	COG4213	ABC transporter substrate-binding protein
Clocl_4056	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Clocl_4056	COG0189	ligase activity
Clocl_4057	COG4242	Belongs to the peptidase S51 family
Clocl_4059	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Clocl_4060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Clocl_4061	COG0473	3-isopropylmalate dehydrogenase activity
Clocl_4066	COG0028	Belongs to the TPP enzyme family
Clocl_4068	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Clocl_4069	COG1073	alpha beta
Clocl_4074	COG1516	flagellar protein fliS
Clocl_4075	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Clocl_4077	COG1088	dTDP-glucose 4,6-dehydratase activity
Clocl_4078	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Clocl_4081	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Clocl_4082	COG2089	acid synthase
Clocl_4084	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Clocl_4086	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Clocl_4087	COG2226	methyltransferase
Clocl_4092	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Clocl_4093	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Clocl_4094	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Clocl_4095	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Clocl_4096	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Clocl_4098	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Clocl_4099	COG4786	Flagellar basal body rod
Clocl_4099	COG1256	bacterial-type flagellum assembly
Clocl_4100	COG1256	bacterial-type flagellum assembly
Clocl_4100	COG4786	Flagellar basal body rod
Clocl_4104	COG1040	competence protein
Clocl_4105	COG0668	transmembrane transport
Clocl_4108	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Clocl_4111	COG1773	rubredoxin
Clocl_4116	COG0254	rRNA binding
Clocl_4117	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Clocl_4121	COG1120	ATPase activity
Clocl_4122	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Clocl_4130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Clocl_4131	COG1295	ribonuclease BN
Clocl_4132	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Clocl_4133	COG0629	single-stranded DNA binding
Clocl_4134	COG0360	Binds together with S18 to 16S ribosomal RNA
Clocl_4135	COG3706	GGDEF domain
Clocl_4137	COG1191	sigma factor activity
Clocl_4140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Clocl_4141	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Clocl_4142	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Clocl_4143	COG0440	acetolactate synthase activity
Clocl_4144	COG0028	Belongs to the TPP enzyme family
Clocl_4147	COG0590	tRNA wobble adenosine to inosine editing
Clocl_4148	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Clocl_4153	COG0551	DNA topoisomerase type I activity
Clocl_4153	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Clocl_4155	COG1305	Transglutaminase-like
Clocl_4157	COG0714	Associated with various cellular activities
Clocl_4158	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clocl_4158	COG5297	Belongs to the glycosyl hydrolase family 6
Clocl_4161	COG3401	FG-GAP repeat protein
Clocl_4167	COG1609	Transcriptional regulator
Clocl_4168	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Clocl_4169	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Clocl_4174	COG5002	protein histidine kinase activity
Clocl_4175	COG0745	RESPONSE REGULATOR receiver
Clocl_4179	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Clocl_4180	COG2089	acid synthase
Clocl_4182	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Clocl_4183	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Clocl_4184	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Clocl_4191	COG1088	dTDP-glucose 4,6-dehydratase activity
Clocl_4192	COG0463	Glycosyl transferase, family 2
Clocl_4194	COG1216	Glycosyl transferase, family 2
Clocl_4195	COG0438	transferase activity, transferring glycosyl groups
Clocl_4195	COG4641	Protein conserved in bacteria
Clocl_4198	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Clocl_4205	COG3773	Cell wall hydrolase
Clocl_4207	COG0517	IMP dehydrogenase activity
Clocl_4214	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Clocl_4215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Clocl_4221	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Clocl_4222	COG1475	DNA binding
Clocl_4223	COG0357	Ribosomal RNA small subunit methyltransferase G
Clocl_4224	COG0445	tRNA wobble uridine modification
Clocl_4225	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Clocl_4226	COG1847	R3H domain protein
Clocl_4227	COG0706	membrane insertase activity
Clocl_4228	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Clocl_4230	COG0230	Belongs to the bacterial ribosomal protein bL34 family