locus-tag	class	description
Clo1313_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Clo1313_0002	COG0592	DNA-directed DNA polymerase activity
Clo1313_0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Clo1313_0006	COG0187	DNA topoisomerase II activity
Clo1313_0007	COG1192	Involved in chromosome partitioning
Clo1313_0008	COG1475	DNA binding
Clo1313_0011	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Clo1313_0012	COG2814	Major facilitator Superfamily
Clo1313_0014	COG2373	Large extracellular alpha-helical protein
Clo1313_0016	COG2720	vancomycin resistance protein
Clo1313_0020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Clo1313_0022	COG0674	pyruvate-flavodoxin oxidoreductase activity
Clo1313_0023	COG1013	pyruvate-flavodoxin oxidoreductase activity
Clo1313_0030	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Clo1313_0034	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Clo1313_0035	COG1802	Transcriptional regulator
Clo1313_0036	COG2608	mercury ion transmembrane transporter activity
Clo1313_0038	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Clo1313_0043	COG4717	serine-type aminopeptidase activity
Clo1313_0044	COG0791	NLP P60 protein
Clo1313_0047	COG2959	enzyme of heme biosynthesis
Clo1313_0051	COG1078	dGTPase activity
Clo1313_0058	COG3872	metal-dependent enzyme
Clo1313_0059	COG2890	protein-(glutamine-N5) methyltransferase activity
Clo1313_0061	COG4656	Part of a membrane complex involved in electron transport
Clo1313_0062	COG4658	electron transport chain
Clo1313_0063	COG4659	FMN binding
Clo1313_0064	COG4660	Part of a membrane complex involved in electron transport
Clo1313_0065	COG4657	Part of a membrane complex involved in electron transport
Clo1313_0066	COG2878	Part of a membrane complex involved in electron transport
Clo1313_0072	COG1349	DNA-binding transcription factor activity
Clo1313_0073	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Clo1313_0074	COG3959	Transketolase, thiamine diphosphate binding domain
Clo1313_0075	COG3958	Transketolase
Clo1313_0076	COG1063	alcohol dehydrogenase
Clo1313_0077	COG1879	ABC-type sugar transport system periplasmic component
Clo1313_0078	COG1129	ABC transporter
Clo1313_0080	COG0406	alpha-ribazole phosphatase activity
Clo1313_0081	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Clo1313_0082	COG1164	Oligoendopeptidase f
Clo1313_0084	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_0085	COG0590	tRNA wobble adenosine to inosine editing
Clo1313_0087	COG0662	Cupin 2, conserved barrel domain protein
Clo1313_0088	COG3584	3D domain protein
Clo1313_0089	COG1609	Transcriptional regulator
Clo1313_0094	COG0668	transmembrane transport
Clo1313_0096	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Clo1313_0098	COG0590	tRNA wobble adenosine to inosine editing
Clo1313_0099	COG0028	Belongs to the TPP enzyme family
Clo1313_0100	COG0440	acetolactate synthase activity
Clo1313_0101	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Clo1313_0102	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Clo1313_0104	COG1191	sigma factor activity
Clo1313_0107	COG1959	2 iron, 2 sulfur cluster binding
Clo1313_0108	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Clo1313_0110	COG0181	hydroxymethylbilane synthase activity
Clo1313_0112	COG0113	porphobilinogen synthase activity
Clo1313_0113	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Clo1313_0114	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Clo1313_0115	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Clo1313_0116	COG4208	sulfate ABC transporter
Clo1313_0118	COG0175	sulfate reduction
Clo1313_0119	COG0175	sulfate reduction
Clo1313_0122	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Clo1313_0127	COG1595	DNA-templated transcription, initiation
Clo1313_0133	COG3534	alpha-L-arabinofuranosidase
Clo1313_0135	COG5297	Belongs to the glycosyl hydrolase family 6
Clo1313_0137	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Clo1313_0139	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Clo1313_0142	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Clo1313_0143	COG1216	Glycosyl transferase, family 2
Clo1313_0144	COG1088	dTDP-glucose 4,6-dehydratase activity
Clo1313_0146	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Clo1313_0150	COG3328	transposase activity
Clo1313_0152	COG1032	radical SAM domain protein
Clo1313_0160	COG1116	anion transmembrane transporter activity
Clo1313_0161	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clo1313_0162	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Clo1313_0164	COG2954	triphosphatase activity
Clo1313_0168	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Clo1313_0169	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Clo1313_0170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Clo1313_0172	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Clo1313_0172	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Clo1313_0175	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Clo1313_0177	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_0180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Clo1313_0181	COG0428	transporter
Clo1313_0182	COG0009	L-threonylcarbamoyladenylate synthase
Clo1313_0184	COG0698	ribose 5-phosphate isomerase
Clo1313_0185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Clo1313_0186	COG2131	deaminase
Clo1313_0187	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Clo1313_0188	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Clo1313_0189	COG0356	it plays a direct role in the translocation of protons across the membrane
Clo1313_0190	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Clo1313_0191	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Clo1313_0192	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Clo1313_0193	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Clo1313_0194	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Clo1313_0195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Clo1313_0196	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Clo1313_0200	COG3266	domain, Protein
Clo1313_0200	COG2911	Protein conserved in bacteria
Clo1313_0200	COG1361	Conserved repeat domain
Clo1313_0202	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Clo1313_0203	COG2385	sporulation resulting in formation of a cellular spore
Clo1313_0205	COG1609	Transcriptional regulator
Clo1313_0207	COG4786	Flagellar basal body rod
Clo1313_0211	COG1136	(ABC) transporter
Clo1313_0211	COG0577	efflux transmembrane transporter activity
Clo1313_0213	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Clo1313_0214	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Clo1313_0215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Clo1313_0216	COG2088	sporulation resulting in formation of a cellular spore
Clo1313_0217	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Clo1313_0219	COG0193	aminoacyl-tRNA hydrolase activity
Clo1313_0220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Clo1313_0221	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Clo1313_0223	COG1917	Cupin 2, conserved barrel domain protein
Clo1313_0223	COG2207	Transcriptional regulator
Clo1313_0224	COG0259	pyridoxamine-phosphate oxidase activity
Clo1313_0225	COG0728	peptidoglycan biosynthetic process
Clo1313_0229	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Clo1313_0230	COG2089	acid synthase
Clo1313_0232	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Clo1313_0233	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Clo1313_0234	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Clo1313_0236	COG1181	Belongs to the D-alanine--D-alanine ligase family
Clo1313_0237	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Clo1313_0243	COG4464	protein tyrosine phosphatase activity
Clo1313_0244	COG2002	toxin-antitoxin pair type II binding
Clo1313_0245	COG3956	TIGRFAM MazG family protein
Clo1313_0247	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Clo1313_0251	COG1098	S1 RNA binding domain
Clo1313_0253	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Clo1313_0270	COG0793	Belongs to the peptidase S41A family
Clo1313_0275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Clo1313_0276	COG0849	cell division
Clo1313_0277	COG1607	acyl-coa hydrolase
Clo1313_0278	COG2244	polysaccharide biosynthetic process
Clo1313_0280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Clo1313_0282	COG0110	maltose O-acetyltransferase activity
Clo1313_0287	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Clo1313_0287	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Clo1313_0288	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Clo1313_0289	COG0864	Transcriptional regulator
Clo1313_0290	COG2337	Toxic component of a toxin-antitoxin (TA) module
Clo1313_0293	COG0438	transferase activity, transferring glycosyl groups
Clo1313_0294	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Clo1313_0295	COG3959	Transketolase, thiamine diphosphate binding domain
Clo1313_0296	COG3958	Transketolase
Clo1313_0297	COG1131	(ABC) transporter
Clo1313_0301	COG3949	Membrane
Clo1313_0304	COG0129	dihydroxy-acid dehydratase activity
Clo1313_0305	COG0028	Belongs to the TPP enzyme family
Clo1313_0308	COG0250	Participates in transcription elongation, termination and antitermination
Clo1313_0309	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Clo1313_0310	COG0081	regulation of translation
Clo1313_0311	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Clo1313_0313	COG0085	RNA polymerase activity
Clo1313_0314	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Clo1313_0315	COG1358	cellular component organization or biogenesis
Clo1313_0316	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Clo1313_0317	COG0049	tRNA binding
Clo1313_0318	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Clo1313_0319	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Clo1313_0323	COG2720	vancomycin resistance protein
Clo1313_0325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Clo1313_0326	COG0322	excinuclease ABC activity
Clo1313_0328	COG0544	peptidyl-prolyl cis-trans isomerase activity
Clo1313_0329	COG0740	serine-type endopeptidase activity
Clo1313_0330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Clo1313_0331	COG0470	DNA polymerase III
Clo1313_0331	COG1067	ATP-dependent peptidase activity
Clo1313_0332	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Clo1313_0333	COG0741	lytic transglycosylase activity
Clo1313_0336	COG0613	PHP domain protein
Clo1313_0337	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Clo1313_0341	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Clo1313_0346	COG3263	regulation of cellular component size
Clo1313_0348	COG3708	Transcriptional regulator
Clo1313_0348	COG2207	Transcriptional regulator
Clo1313_0349	COG4733	cellulase activity
Clo1313_0349	COG4447	cellulose binding
Clo1313_0350	COG5297	Belongs to the glycosyl hydrolase family 6
Clo1313_0357	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Clo1313_0358	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
Clo1313_0360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Clo1313_0370	COG1361	Conserved repeat domain
Clo1313_0370	COG2911	Protein conserved in bacteria
Clo1313_0370	COG3266	domain, Protein
Clo1313_0372	COG5012	cobalamin binding
Clo1313_0373	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Clo1313_0378	COG1116	anion transmembrane transporter activity
Clo1313_0379	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clo1313_0380	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Clo1313_0381	COG0436	Aminotransferase
Clo1313_0382	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Clo1313_0384	COG0674	pyruvate-flavodoxin oxidoreductase activity
Clo1313_0385	COG1013	pyruvate-flavodoxin oxidoreductase activity
Clo1313_0387	COG0251	oxidation-reduction process
Clo1313_0388	COG0626	cystathionine gamma-synthase activity
Clo1313_0389	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Clo1313_0390	COG1151	hydroxylamine reductase activity
Clo1313_0392	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clo1313_0393	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Clo1313_0395	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clo1313_0396	COG1609	Transcriptional regulator
Clo1313_0399	COG4124	Belongs to the glycosyl hydrolase 26 family
Clo1313_0400	COG4733	cellulase activity
Clo1313_0400	COG4447	cellulose binding
Clo1313_0402	COG2205	protein histidine kinase activity
Clo1313_0405	COG0835	chemotaxis
Clo1313_0406	COG0643	Histidine kinase
Clo1313_0406	COG2198	Histidine kinase
Clo1313_0406	COG0784	Response regulator, receiver
Clo1313_0408	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Clo1313_0409	COG2201	protein-glutamate methylesterase activity
Clo1313_0411	COG1253	flavin adenine dinucleotide binding
Clo1313_0413	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clo1313_0415	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Clo1313_0421	COG0124	histidyl-tRNA synthetase
Clo1313_0422	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Clo1313_0423	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Clo1313_0424	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Clo1313_0425	COG0131	Imidazoleglycerol-phosphate dehydratase
Clo1313_0426	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Clo1313_0427	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Clo1313_0428	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Clo1313_0429	COG0107	imidazoleglycerol-phosphate synthase activity
Clo1313_0432	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Clo1313_0433	COG0459	protein refolding
Clo1313_0436	COG3858	chitin binding
Clo1313_0438	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Clo1313_0439	COG1366	Belongs to the anti-sigma-factor antagonist family
Clo1313_0441	COG1191	sigma factor activity
Clo1313_0444	COG0051	transcription antitermination factor activity, RNA binding
Clo1313_0445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Clo1313_0446	COG0088	Forms part of the polypeptide exit tunnel
Clo1313_0447	COG0089	rRNA binding
Clo1313_0448	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Clo1313_0449	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Clo1313_0450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Clo1313_0451	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Clo1313_0452	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Clo1313_0453	COG0255	Belongs to the universal ribosomal protein uL29 family
Clo1313_0454	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Clo1313_0455	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Clo1313_0456	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Clo1313_0457	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Clo1313_0458	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Clo1313_0459	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Clo1313_0460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Clo1313_0461	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Clo1313_0462	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Clo1313_0463	COG1841	ribosomal large subunit assembly
Clo1313_0464	COG0200	Binds to the 23S rRNA
Clo1313_0465	COG0201	protein transport
Clo1313_0466	COG0563	adenylate kinase activity
Clo1313_0469	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Clo1313_0470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Clo1313_0471	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Clo1313_0472	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Clo1313_0473	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Clo1313_0474	COG0202	RNA polymerase activity
Clo1313_0475	COG0203	ribosomal protein L17
Clo1313_0476	COG1122	ATPase activity
Clo1313_0477	COG2813	Specifically methylates the guanine in position
Clo1313_0486	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Clo1313_0487	COG1122	ATPase activity
Clo1313_0488	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Clo1313_0489	COG1940	carbohydrate kinase activity
Clo1313_0490	COG0101	tRNA pseudouridine synthase activity
Clo1313_0491	COG1329	Transcriptional regulator
Clo1313_0492	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Clo1313_0493	COG4555	ABC transporter
Clo1313_0494	COG1668	transmembrane transport
Clo1313_0495	COG4191	Histidine kinase
Clo1313_0495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Clo1313_0496	COG3290	protein histidine kinase activity
Clo1313_0497	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Clo1313_0498	COG0442	prolyl-tRNA aminoacylation
Clo1313_0499	COG2340	Cysteine-rich secretory protein family
Clo1313_0500	COG2273	Hydrolase Family 16
Clo1313_0501	COG3250	beta-galactosidase activity
Clo1313_0510	COG4166	transmembrane transport
Clo1313_0511	COG4608	Belongs to the ABC transporter superfamily
Clo1313_0512	COG0444	Belongs to the ABC transporter superfamily
Clo1313_0513	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Clo1313_0514	COG0601	transmembrane transport
Clo1313_0518	COG1725	Transcriptional regulator
Clo1313_0519	COG1131	(ABC) transporter
Clo1313_0523	COG1489	DNA binding
Clo1313_0524	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Clo1313_0525	COG1191	sigma factor activity
Clo1313_0532	COG0840	transmembrane signaling receptor activity
Clo1313_0541	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Clo1313_0547	COG0693	protein deglycase activity
Clo1313_0549	COG1132	(ABC) transporter
Clo1313_0551	COG0306	phosphate transporter
Clo1313_0555	COG1388	LysM domain
Clo1313_0556	COG1376	ErfK ybiS ycfS ynhG family protein
Clo1313_0563	COG5520	Belongs to the glycosyl hydrolase 30 family
Clo1313_0565	COG0409	Hydrogenase expression formation protein
Clo1313_0567	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Clo1313_0571	COG3261	NADH dehydrogenase
Clo1313_0571	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Clo1313_0573	COG3260	NADH ubiquinone oxidoreductase 20
Clo1313_0575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Clo1313_0575	COG2111	Na H antiporter
Clo1313_0577	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Clo1313_0578	COG0372	Belongs to the citrate synthase family
Clo1313_0579	COG0076	glutamate decarboxylase activity
Clo1313_0580	COG0835	chemotaxis
Clo1313_0581	COG0840	transmembrane signaling receptor activity
Clo1313_0586	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Clo1313_0587	COG0840	transmembrane signaling receptor activity
Clo1313_0594	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Clo1313_0598	COG0768	penicillin binding
Clo1313_0599	COG2003	Belongs to the UPF0758 family
Clo1313_0602	COG3328	transposase activity
Clo1313_0610	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Clo1313_0613	COG3458	cephalosporin-C deacetylase activity
Clo1313_0616	COG1131	(ABC) transporter
Clo1313_0618	COG5002	protein histidine kinase activity
Clo1313_0619	COG0745	RESPONSE REGULATOR receiver
Clo1313_0623	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Clo1313_0624	COG0561	phosphatase activity
Clo1313_0625	COG2304	oxidoreductase activity
Clo1313_0627	COG2911	Protein conserved in bacteria
Clo1313_0628	COG3266	domain, Protein
Clo1313_0628	COG2911	Protein conserved in bacteria
Clo1313_0628	COG1361	Conserved repeat domain
Clo1313_0629	COG1361	Conserved repeat domain
Clo1313_0630	COG1361	Conserved repeat domain
Clo1313_0634	COG0116	Belongs to the methyltransferase superfamily
Clo1313_0636	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Clo1313_0640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Clo1313_0643	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Clo1313_0645	COG0463	Glycosyl transferase, family 2
Clo1313_0648	COG0463	Glycosyl transferase, family 2
Clo1313_0650	COG1216	Glycosyl transferase, family 2
Clo1313_0651	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Clo1313_0652	COG0436	Aminotransferase
Clo1313_0653	COG1316	TRANSCRIPTIONal
Clo1313_0656	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Clo1313_0657	COG0720	synthase
Clo1313_0658	COG0602	queuosine metabolic process
Clo1313_0659	COG1573	uracil-dna glycosylase
Clo1313_0660	COG1573	uracil-dna glycosylase
Clo1313_0661	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Clo1313_0665	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Clo1313_0666	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Clo1313_0669	COG1482	cell wall glycoprotein biosynthetic process
Clo1313_0671	COG2703	oxygen carrier activity
Clo1313_0672	COG1773	rubredoxin
Clo1313_0672	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Clo1313_0675	COG1361	Conserved repeat domain
Clo1313_0677	COG0318	PFAM AMP-dependent synthetase and ligase
Clo1313_0679	COG1056	cytidyltransferase-related domain
Clo1313_0679	COG1051	belongs to the nudix hydrolase family
Clo1313_0682	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Clo1313_0685	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Clo1313_0686	COG2267	carboxylic ester hydrolase activity
Clo1313_0689	COG1404	Belongs to the peptidase S8 family
Clo1313_0693	COG2755	lipolytic protein G-D-S-L family
Clo1313_0693	COG3401	FG-GAP repeat protein
Clo1313_0698	COG1132	(ABC) transporter
Clo1313_0699	COG1132	(ABC) transporter
Clo1313_0700	COG2195	Cleaves the N-terminal amino acid of tripeptides
Clo1313_0703	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Clo1313_0707	COG0840	transmembrane signaling receptor activity
Clo1313_0708	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Clo1313_0709	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Clo1313_0710	COG1802	Transcriptional regulator
Clo1313_0711	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Clo1313_0711	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Clo1313_0712	COG1187	pseudouridine synthase activity
Clo1313_0717	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Clo1313_0718	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Clo1313_0719	COG1597	lipid kinase activity
Clo1313_0721	COG1136	(ABC) transporter
Clo1313_0723	COG0577	efflux transmembrane transporter activity
Clo1313_0723	COG1136	(ABC) transporter
Clo1313_0726	COG2323	membrane
Clo1313_0730	COG1686	Belongs to the peptidase S11 family
Clo1313_0732	COG0569	domain protein
Clo1313_0739	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Clo1313_0748	COG0628	permease
Clo1313_0749	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Clo1313_0766	COG3328	transposase activity
Clo1313_0785	COG3328	transposase activity
Clo1313_0790	COG3328	transposase activity
Clo1313_0791	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Clo1313_0791	COG0723	plastoquinol--plastocyanin reductase activity
Clo1313_0795	COG1126	abc transporter atp-binding protein
Clo1313_0805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Clo1313_0811	COG1595	DNA-templated transcription, initiation
Clo1313_0815	COG1028	Short-chain dehydrogenase reductase Sdr
Clo1313_0822	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Clo1313_0823	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Clo1313_0825	COG0628	permease
Clo1313_0828	COG1714	RDD family
Clo1313_0829	COG0616	signal peptide processing
Clo1313_0830	COG1971	Probably functions as a manganese efflux pump
Clo1313_0833	COG1131	(ABC) transporter
Clo1313_0836	COG0133	tryptophan synthase activity
Clo1313_0837	COG0159	tryptophan synthase activity
Clo1313_0838	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Clo1313_0839	COG5002	protein histidine kinase activity
Clo1313_0841	COG0745	RESPONSE REGULATOR receiver
Clo1313_0844	COG5337	Spore coat protein CotH
Clo1313_0845	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Clo1313_0847	COG1321	iron dependent repressor
Clo1313_0851	COG4447	cellulose binding
Clo1313_0852	COG1442	glycosyl transferase family 8
Clo1313_0853	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Clo1313_0855	COG0745	RESPONSE REGULATOR receiver
Clo1313_0856	COG5002	protein histidine kinase activity
Clo1313_0857	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Clo1313_0858	COG2267	carboxylic ester hydrolase activity
Clo1313_0859	COG0617	tRNA 3'-terminal CCA addition
Clo1313_0860	COG4496	protein, YerC YecD
Clo1313_0863	COG0653	protein targeting
Clo1313_0864	COG0285	dihydrofolate synthase activity
Clo1313_0866	COG1752	Esterase of the alpha-beta hydrolase superfamily
Clo1313_0868	COG2201	protein-glutamate methylesterase activity
Clo1313_0869	COG0673	inositol 2-dehydrogenase activity
Clo1313_0870	COG2199	diguanylate cyclase activity
Clo1313_0870	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Clo1313_0871	COG4492	Belongs to the UPF0735 family
Clo1313_0872	COG0460	homoserine dehydrogenase
Clo1313_0873	COG0527	aspartate kinase activity
Clo1313_0883	COG0537	adenosine 5'-monophosphoramidase activity
Clo1313_0884	COG1361	Conserved repeat domain
Clo1313_0886	COG4464	protein tyrosine phosphatase activity
Clo1313_0890	COG0489	protein tyrosine kinase activity
Clo1313_0898	COG1216	Glycosyl transferase, family 2
Clo1313_0901	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Clo1313_0903	COG0629	single-stranded DNA binding
Clo1313_0904	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Clo1313_0905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Clo1313_0907	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Clo1313_0907	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Clo1313_0908	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Clo1313_0909	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Clo1313_0910	COG1490	D-aminoacyl-tRNA deacylase activity
Clo1313_0911	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Clo1313_0912	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Clo1313_0922	COG0124	histidyl-tRNA synthetase
Clo1313_0923	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Clo1313_0929	COG0481	GTPase activity
Clo1313_0930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Clo1313_0931	COG1420	regulation of RNA biosynthetic process
Clo1313_0932	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Clo1313_0933	COG0443	Heat shock 70 kDa protein
Clo1313_0934	COG0484	heat shock protein binding
Clo1313_0935	COG2264	protein methyltransferase activity
Clo1313_0936	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Clo1313_0937	COG2201	protein-glutamate methylesterase activity
Clo1313_0939	COG1561	YicC-like family, N-terminal region
Clo1313_0940	COG2052	Domain of unknown function (DUF370)
Clo1313_0941	COG0194	GDP metabolic process
Clo1313_0942	COG1758	RNA polymerase activity
Clo1313_0943	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Clo1313_0944	COG0423	glycine-tRNA ligase activity
Clo1313_0945	COG3290	protein histidine kinase activity
Clo1313_0948	COG0535	radical SAM domain protein
Clo1313_0949	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Clo1313_0949	COG0574	Belongs to the PEP-utilizing enzyme family
Clo1313_0950	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_0952	COG0662	Cupin 2, conserved barrel domain protein
Clo1313_0953	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Clo1313_0955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Clo1313_0956	COG1323	Belongs to the UPF0348 family
Clo1313_0960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Clo1313_0962	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Clo1313_0966	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Clo1313_0970	COG0745	RESPONSE REGULATOR receiver
Clo1313_0971	COG3850	Histidine kinase
Clo1313_0971	COG5002	protein histidine kinase activity
Clo1313_0972	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Clo1313_0973	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Clo1313_0973	COG2199	diguanylate cyclase activity
Clo1313_0974	COG0297	glycogen (starch) synthase activity
Clo1313_0975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Clo1313_0978	COG2261	transglycosylase associated protein
Clo1313_0979	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Clo1313_0980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Clo1313_0981	COG0742	ribosomal rna small subunit methyltransferase
Clo1313_0982	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Clo1313_0984	COG3314	Sporulation integral membrane protein YlbJ
Clo1313_0985	COG2755	lipolytic protein G-D-S-L family
Clo1313_0986	COG1191	sigma factor activity
Clo1313_0987	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_0991	COG2197	response regulator
Clo1313_0992	COG0840	transmembrane signaling receptor activity
Clo1313_0993	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Clo1313_0997	COG0205	6-phosphofructokinase activity
Clo1313_1002	COG1472	Belongs to the glycosyl hydrolase 3 family
Clo1313_1007	COG2252	PERMEase
Clo1313_1008	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Clo1313_1009	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Clo1313_1010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Clo1313_1011	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Clo1313_1012	COG0138	bifunctional purine biosynthesis protein purh
Clo1313_1013	COG0151	Belongs to the GarS family
Clo1313_1014	COG1216	Glycosyl transferase, family 2
Clo1313_1016	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Clo1313_1017	COG1713	HD superfamily hydrolase involved in NAD metabolism
Clo1313_1019	COG0799	negative regulation of ribosome biogenesis
Clo1313_1020	COG0495	leucyl-tRNA aminoacylation
Clo1313_1022	COG0840	transmembrane signaling receptor activity
Clo1313_1024	COG1022	Amp-dependent synthetase and ligase
Clo1313_1025	COG1686	Belongs to the peptidase S11 family
Clo1313_1026	COG1596	polysaccharide export
Clo1313_1026	COG1555	photosystem II stabilization
Clo1313_1029	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Clo1313_1031	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Clo1313_1032	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Clo1313_1033	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Clo1313_1034	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Clo1313_1035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Clo1313_1036	COG3459	Glycosyltransferase 36 associated
Clo1313_1039	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Clo1313_1040	COG0542	response to heat
Clo1313_1041	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Clo1313_1042	COG0730	response to heat
Clo1313_1046	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
Clo1313_1052	COG2766	serine protein kinase
Clo1313_1053	COG2718	Belongs to the UPF0229 family
Clo1313_1054	COG2719	SpoVR family
Clo1313_1057	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Clo1313_1058	COG0402	S-adenosylhomocysteine deaminase activity
Clo1313_1066	COG3328	transposase activity
Clo1313_1068	COG0546	phosphoglycolate phosphatase activity
Clo1313_1070	COG4555	ABC transporter
Clo1313_1073	COG0657	acetylesterase activity
Clo1313_1076	COG0714	Associated with various cellular activities
Clo1313_1078	COG1305	Transglutaminase-like
Clo1313_1082	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Clo1313_1083	COG1406	Chemotaxis phosphatase CheX
Clo1313_1090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Clo1313_1093	COG3885	ferrous iron binding
Clo1313_1093	COG2078	PFAM AMMECR1 domain protein
Clo1313_1095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Clo1313_1097	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Clo1313_1098	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Clo1313_1099	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Clo1313_1100	COG0640	Transcriptional regulator
Clo1313_1101	COG0798	PFAM Bile acid sodium symporter
Clo1313_1106	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Clo1313_1108	COG1459	type II secretion system
Clo1313_1116	COG0740	serine-type endopeptidase activity
Clo1313_1118	COG1674	ftsk spoiiie
Clo1313_1120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Clo1313_1122	COG1418	mRNA catabolic process
Clo1313_1123	COG1692	metallophosphoesterase
Clo1313_1124	COG2359	stage V sporulation protein S
Clo1313_1128	COG0438	transferase activity, transferring glycosyl groups
Clo1313_1130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Clo1313_1134	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Clo1313_1142	COG1702	phosphate starvation-inducible protein PhoH
Clo1313_1143	COG1480	7TM receptor with intracellular HD hydrolase
Clo1313_1144	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Clo1313_1145	COG0295	cytidine deaminase activity
Clo1313_1146	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Clo1313_1148	COG1381	Involved in DNA repair and RecF pathway recombination
Clo1313_1150	COG1104	cysteine desulfurase activity
Clo1313_1151	COG0301	tRNA thio-modification
Clo1313_1152	COG2720	vancomycin resistance protein
Clo1313_1155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Clo1313_1156	COG1983	PspC domain protein
Clo1313_1157	COG1305	Transglutaminase-like
Clo1313_1159	COG0714	Associated with various cellular activities
Clo1313_1160	COG0039	L-malate dehydrogenase activity
Clo1313_1161	COG1058	Belongs to the CinA family
Clo1313_1161	COG1546	Belongs to the CinA family
Clo1313_1162	COG0728	peptidoglycan biosynthetic process
Clo1313_1163	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Clo1313_1165	COG0705	Rhomboid family
Clo1313_1165	COG0457	Tetratricopeptide repeat
Clo1313_1172	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Clo1313_1173	COG1466	dna polymerase III delta subunit
Clo1313_1174	COG0268	Binds directly to 16S ribosomal RNA
Clo1313_1178	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Clo1313_1181	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Clo1313_1182	COG0154	amidase activity
Clo1313_1183	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Clo1313_1185	COG0280	phosphate acetyltransferase
Clo1313_1186	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Clo1313_1188	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Clo1313_1190	COG1160	GTP binding
Clo1313_1192	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Clo1313_1193	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Clo1313_1195	COG1175	transmembrane transport
Clo1313_1196	COG0395	ABC-type sugar transport system, permease component
Clo1313_1198	COG0860	N-Acetylmuramoyl-L-alanine amidase
Clo1313_1198	COG2247	cell wall binding repeat
Clo1313_1201	COG1193	negative regulation of DNA recombination
Clo1313_1202	COG0628	permease
Clo1313_1204	COG0768	penicillin binding
Clo1313_1205	COG0826	peptidase U32
Clo1313_1206	COG4122	O-methyltransferase activity
Clo1313_1207	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Clo1313_1208	COG1217	gtp-binding protein TYPA
Clo1313_1209	COG0052	Belongs to the universal ribosomal protein uS2 family
Clo1313_1210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Clo1313_1211	COG0528	UMP kinase activity
Clo1313_1212	COG0233	cytoplasmic translational termination
Clo1313_1214	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Clo1313_1215	COG0575	Belongs to the CDS family
Clo1313_1216	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Clo1313_1218	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Clo1313_1221	COG0779	Required for maturation of 30S ribosomal subunits
Clo1313_1222	COG0195	Participates in both transcription termination and antitermination
Clo1313_1223	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Clo1313_1225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Clo1313_1226	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Clo1313_1227	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Clo1313_1228	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Clo1313_1229	COG0196	riboflavin kinase activity
Clo1313_1231	COG0612	Peptidase, M16
Clo1313_1232	COG0612	Peptidase, M16
Clo1313_1233	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Clo1313_1235	COG0772	Belongs to the SEDS family
Clo1313_1236	COG2001	Belongs to the MraZ family
Clo1313_1237	COG0275	rRNA processing
Clo1313_1239	COG0768	penicillin binding
Clo1313_1240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Clo1313_1241	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Clo1313_1242	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Clo1313_1243	COG0772	Belongs to the SEDS family
Clo1313_1244	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Clo1313_1245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Clo1313_1248	COG3328	transposase activity
Clo1313_1251	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Clo1313_1253	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Clo1313_1254	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Clo1313_1255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Clo1313_1256	COG2247	cell wall binding repeat
Clo1313_1256	COG2385	sporulation resulting in formation of a cellular spore
Clo1313_1257	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Clo1313_1258	COG0343	queuine tRNA-ribosyltransferase activity
Clo1313_1259	COG1862	Preprotein translocase
Clo1313_1262	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Clo1313_1264	COG0540	Belongs to the ATCase OTCase family
Clo1313_1265	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Clo1313_1268	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Clo1313_1269	COG0543	2 iron, 2 sulfur cluster binding
Clo1313_1270	COG0167	dihydroorotate dehydrogenase activity
Clo1313_1271	COG0588	phosphoglycerate mutase activity
Clo1313_1275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Clo1313_1276	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Clo1313_1279	COG2030	dehydratase
Clo1313_1280	COG0416	fatty acid biosynthetic process
Clo1313_1281	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Clo1313_1282	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Clo1313_1283	COG1028	Short-chain dehydrogenase reductase Sdr
Clo1313_1284	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Clo1313_1285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Clo1313_1286	COG0571	ribonuclease III activity
Clo1313_1288	COG2359	stage V sporulation protein S
Clo1313_1291	COG0552	protein localization to endoplasmic reticulum
Clo1313_1295	COG1748	Saccharopine dehydrogenase
Clo1313_1301	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Clo1313_1306	COG1496	oxidoreductase activity
Clo1313_1309	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Clo1313_1310	COG0564	pseudouridine synthase activity
Clo1313_1313	COG1418	mRNA catabolic process
Clo1313_1314	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Clo1313_1315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Clo1313_1316	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Clo1313_1317	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Clo1313_1318	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Clo1313_1321	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Clo1313_1323	COG0358	DNA primase activity
Clo1313_1324	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Clo1313_1327	COG2384	SAM-dependent methyltransferase
Clo1313_1328	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Clo1313_1329	COG3437	response regulator, receiver
Clo1313_1330	COG1595	DNA-templated transcription, initiation
Clo1313_1334	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Clo1313_1334	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Clo1313_1335	COG0237	dephospho-CoA kinase activity
Clo1313_1338	COG0697	spore germination
Clo1313_1339	COG3706	GGDEF domain
Clo1313_1340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Clo1313_1341	COG0835	chemotaxis
Clo1313_1342	COG0012	GTP binding
Clo1313_1345	COG0512	Glutamine amidotransferase of anthranilate synthase
Clo1313_1345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Clo1313_1346	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Clo1313_1347	COG0134	indole-3-glycerol-phosphate synthase activity
Clo1313_1348	COG0135	phosphoribosylanthranilate isomerase activity
Clo1313_1359	COG1316	TRANSCRIPTIONal
Clo1313_1360	COG1592	Rubrerythrin
Clo1313_1362	COG4864	UPF0365 protein
Clo1313_1363	COG1030	water channel activity
Clo1313_1364	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Clo1313_1365	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Clo1313_1366	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Clo1313_1367	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Clo1313_1368	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Clo1313_1370	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Clo1313_1371	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Clo1313_1372	COG0006	proline dipeptidase activity
Clo1313_1373	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Clo1313_1376	COG3854	ATPases associated with a variety of cellular activities
Clo1313_1384	COG1302	Protein conserved in bacteria
Clo1313_1387	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Clo1313_1388	COG1570	exodeoxyribonuclease VII activity
Clo1313_1389	COG1722	exodeoxyribonuclease VII activity
Clo1313_1391	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Clo1313_1393	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Clo1313_1394	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Clo1313_1396	COG3291	Pkd domain containing protein
Clo1313_1401	COG1131	(ABC) transporter
Clo1313_1404	COG3706	GGDEF domain
Clo1313_1405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Clo1313_1406	COG1438	arginine binding
Clo1313_1407	COG0497	DNA recombination
Clo1313_1408	COG0750	zinc metalloprotease
Clo1313_1409	COG0745	RESPONSE REGULATOR receiver
Clo1313_1410	COG2201	protein-glutamate methylesterase activity
Clo1313_1411	COG0643	Histidine kinase
Clo1313_1411	COG2198	Histidine kinase
Clo1313_1412	COG0835	chemotaxis
Clo1313_1414	COG2201	protein-glutamate methylesterase activity
Clo1313_1416	COG0745	RESPONSE REGULATOR receiver
Clo1313_1418	COG0564	pseudouridine synthase activity
Clo1313_1421	COG3328	transposase activity
Clo1313_1422	COG5002	protein histidine kinase activity
Clo1313_1423	COG0745	RESPONSE REGULATOR receiver
Clo1313_1425	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clo1313_1425	COG2755	lipolytic protein G-D-S-L family
Clo1313_1426	COG0366	Alpha amylase catalytic
Clo1313_1427	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Clo1313_1429	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Clo1313_1430	COG1799	cell septum assembly
Clo1313_1432	COG2302	S4 RNA-binding domain
Clo1313_1433	COG3599	regulation of cell shape
Clo1313_1435	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Clo1313_1438	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Clo1313_1440	COG0840	transmembrane signaling receptor activity
Clo1313_1442	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Clo1313_1443	COG2340	Cysteine-rich secretory protein family
Clo1313_1445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Clo1313_1446	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Clo1313_1447	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Clo1313_1448	COG1923	regulation of RNA biosynthetic process
Clo1313_1449	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Clo1313_1451	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Clo1313_1452	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Clo1313_1453	COG0228	four-way junction DNA binding
Clo1313_1454	COG1837	Belongs to the UPF0109 family
Clo1313_1455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Clo1313_1456	COG0336	Belongs to the RNA methyltransferase TrmD family
Clo1313_1457	COG0335	large ribosomal subunit rRNA binding
Clo1313_1461	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Clo1313_1464	COG0792	nuclease activity
Clo1313_1465	COG2003	Belongs to the UPF0758 family
Clo1313_1472	COG3842	ATPase activity
Clo1313_1473	COG1176	ABC-type spermidine putrescine transport system, permease component I
Clo1313_1477	COG4733	cellulase activity
Clo1313_1478	COG0793	Belongs to the peptidase S41A family
Clo1313_1478	COG3409	Peptidoglycan-binding domain 1 protein
Clo1313_1479	COG0534	Mate efflux family protein
Clo1313_1481	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Clo1313_1482	COG2188	Transcriptional regulator
Clo1313_1487	COG2911	Protein conserved in bacteria
Clo1313_1487	COG1361	Conserved repeat domain
Clo1313_1487	COG3266	domain, Protein
Clo1313_1488	COG2911	Protein conserved in bacteria
Clo1313_1488	COG1361	Conserved repeat domain
Clo1313_1488	COG3266	domain, Protein
Clo1313_1491	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Clo1313_1494	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Clo1313_1495	COG4974	Belongs to the 'phage' integrase family
Clo1313_1497	COG1362	aminopeptidase activity
Clo1313_1498	COG2199	diguanylate cyclase activity
Clo1313_1498	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Clo1313_1499	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Clo1313_1500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Clo1313_1501	COG0482	sulfurtransferase activity
Clo1313_1502	COG0822	iron-sulfur transferase activity
Clo1313_1504	COG1959	2 iron, 2 sulfur cluster binding
Clo1313_1507	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Clo1313_1508	COG0105	UTP biosynthetic process
Clo1313_1509	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Clo1313_1510	COG0539	negative regulation of cytoplasmic translation
Clo1313_1510	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Clo1313_1511	COG0204	Acyl-transferase
Clo1313_1516	COG2081	HI0933 family
Clo1313_1517	COG0406	alpha-ribazole phosphatase activity
Clo1313_1518	COG1737	Transcriptional regulator
Clo1313_1524	COG0511	ligase activity, forming carbon-carbon bonds
Clo1313_1526	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Clo1313_1528	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Clo1313_1529	COG0010	Belongs to the arginase family
Clo1313_1530	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Clo1313_1531	COG1187	pseudouridine synthase activity
Clo1313_1532	COG3874	Sporulation protein YtfJ
Clo1313_1535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Clo1313_1536	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Clo1313_1537	COG0180	Tryptophanyl-tRNA synthetase
Clo1313_1538	COG1994	Peptidase M50
Clo1313_1539	COG3620	sequence-specific DNA binding
Clo1313_1539	COG0617	tRNA 3'-terminal CCA addition
Clo1313_1539	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Clo1313_1542	COG0516	GMP reductase activity
Clo1313_1542	COG0517	IMP dehydrogenase activity
Clo1313_1544	COG1686	Belongs to the peptidase S11 family
Clo1313_1546	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Clo1313_1547	COG4974	Belongs to the 'phage' integrase family
Clo1313_1548	COG1300	Membrane
Clo1313_1550	COG0328	RNA-DNA hybrid ribonuclease activity
Clo1313_1551	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Clo1313_1557	COG0697	spore germination
Clo1313_1558	COG0330	HflC and HflK could
Clo1313_1560	COG3583	domain protein
Clo1313_1560	COG3584	3D domain protein
Clo1313_1563	COG2273	Hydrolase Family 16
Clo1313_1564	COG4447	cellulose binding
Clo1313_1570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Clo1313_1573	COG1942	4-Oxalocrotonate Tautomerase
Clo1313_1578	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Clo1313_1583	COG3949	Membrane
Clo1313_1587	COG2273	Hydrolase Family 16
Clo1313_1588	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Clo1313_1592	COG0631	protein serine/threonine phosphatase activity
Clo1313_1593	COG2815	serine threonine protein kinase
Clo1313_1593	COG0515	serine threonine protein kinase
Clo1313_1603	COG5297	Belongs to the glycosyl hydrolase family 6
Clo1313_1605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Clo1313_1606	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Clo1313_1607	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Clo1313_1608	COG1321	iron dependent repressor
Clo1313_1610	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Clo1313_1610	COG1918	ferrous iron import across plasma membrane
Clo1313_1612	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Clo1313_1616	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Clo1313_1618	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Clo1313_1619	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Clo1313_1624	COG0791	NLP P60 protein
Clo1313_1627	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Clo1313_1628	COG0352	thiamine-phosphate diphosphorylase activity
Clo1313_1630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Clo1313_1631	COG2022	thiamine diphosphate biosynthetic process
Clo1313_1632	COG2022	thiamine diphosphate biosynthetic process
Clo1313_1632	COG2104	thiamine diphosphate biosynthetic process
Clo1313_1633	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Clo1313_1638	COG2226	methyltransferase
Clo1313_1643	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Clo1313_1645	COG1201	RNA secondary structure unwinding
Clo1313_1654	COG2204	response regulator
Clo1313_1656	COG1293	RNA-binding protein homologous to eukaryotic snRNP
Clo1313_1657	COG0436	Aminotransferase
Clo1313_1658	COG0778	Nitroreductase
Clo1313_1661	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Clo1313_1662	COG1162	GTPase activity
Clo1313_1663	COG0515	serine threonine protein kinase
Clo1313_1663	COG2815	serine threonine protein kinase
Clo1313_1664	COG0631	protein serine/threonine phosphatase activity
Clo1313_1665	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Clo1313_1666	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Clo1313_1666	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Clo1313_1667	COG2738	Putative neutral zinc metallopeptidase
Clo1313_1669	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Clo1313_1670	COG0242	peptide deformylase activity
Clo1313_1671	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Clo1313_1676	COG1477	protein flavinylation
Clo1313_1677	COG1252	NADH dehydrogenase
Clo1313_1680	COG0726	polysaccharide deacetylase
Clo1313_1681	COG0367	asparagine synthase
Clo1313_1682	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Clo1313_1683	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Clo1313_1684	COG0583	DNA-binding transcription factor activity
Clo1313_1686	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Clo1313_1687	COG0326	Molecular chaperone. Has ATPase activity
Clo1313_1688	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Clo1313_1689	COG1121	(ABC) transporter
Clo1313_1690	COG0803	Belongs to the bacterial solute-binding protein 9 family
Clo1313_1691	COG0735	belongs to the Fur family
Clo1313_1693	COG0631	protein serine/threonine phosphatase activity
Clo1313_1694	COG5297	Belongs to the glycosyl hydrolase family 6
Clo1313_1697	COG0577	efflux transmembrane transporter activity
Clo1313_1697	COG1136	(ABC) transporter
Clo1313_1698	COG1136	(ABC) transporter
Clo1313_1699	COG3850	Histidine kinase
Clo1313_1699	COG5002	protein histidine kinase activity
Clo1313_1700	COG0745	RESPONSE REGULATOR receiver
Clo1313_1701	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clo1313_1701	COG4447	cellulose binding
Clo1313_1703	COG2274	protein secretion by the type I secretion system
Clo1313_1711	COG5002	protein histidine kinase activity
Clo1313_1712	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Clo1313_1715	COG2176	DNA-directed DNA polymerase activity
Clo1313_1716	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Clo1313_1718	COG2843	Capsule synthesis protein
Clo1313_1725	COG1191	sigma factor activity
Clo1313_1727	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Clo1313_1728	COG1776	CheC inhibitor of MCP methylation
Clo1313_1729	COG0835	chemotaxis
Clo1313_1730	COG2198	Histidine kinase
Clo1313_1730	COG0643	Histidine kinase
Clo1313_1731	COG2201	protein-glutamate methylesterase activity
Clo1313_1734	COG1419	protein localization to endoplasmic reticulum
Clo1313_1735	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Clo1313_1736	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Clo1313_1737	COG1684	flagellar biosynthetic protein fliR
Clo1313_1738	COG1987	bacterial-type flagellum assembly
Clo1313_1739	COG1338	Plays a role in the flagellum-specific transport system
Clo1313_1741	COG2201	protein-glutamate methylesterase activity
Clo1313_1742	COG1776	CheC inhibitor of MCP methylation
Clo1313_1742	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Clo1313_1743	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Clo1313_1745	COG1582	Flagellar protein (FlbD)
Clo1313_1748	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Clo1313_1752	COG1157	protein secretion by the type III secretion system
Clo1313_1753	COG1317	bacterial-type flagellum organization
Clo1313_1754	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Clo1313_1756	COG1677	Flagellar hook-basal body complex protein FliE
Clo1313_1757	COG1558	bacterial-type flagellum-dependent cell motility
Clo1313_1758	COG1815	bacterial-type flagellum-dependent cell motility
Clo1313_1759	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Clo1313_1760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Clo1313_1761	COG0758	DNA mediated transformation
Clo1313_1761	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Clo1313_1762	COG0708	Exodeoxyribonuclease III
Clo1313_1763	COG3304	Inner membrane component domain
Clo1313_1765	COG0606	chelatase, subunit chli
Clo1313_1770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Clo1313_1771	COG1873	PFAM PRC-barrel domain
Clo1313_1772	COG1191	sigma factor activity
Clo1313_1773	COG1191	sigma factor activity
Clo1313_1775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Clo1313_1776	COG0849	cell division
Clo1313_1777	COG3856	small basic protein
Clo1313_1778	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Clo1313_1780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Clo1313_1781	COG3442	glutamine amidotransferase
Clo1313_1782	COG3328	transposase activity
Clo1313_1783	COG4447	cellulose binding
Clo1313_1790	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Clo1313_1798	COG1012	belongs to the aldehyde dehydrogenase family
Clo1313_1798	COG1454	alcohol dehydrogenase
Clo1313_1799	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Clo1313_1800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Clo1313_1802	COG0612	Peptidase, M16
Clo1313_1803	COG1185	polyribonucleotide nucleotidyltransferase activity
Clo1313_1804	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Clo1313_1807	COG3546	catalase activity
Clo1313_1809	COG2273	Hydrolase Family 16
Clo1313_1809	COG5297	Belongs to the glycosyl hydrolase family 6
Clo1313_1811	COG2848	UPF0210 protein
Clo1313_1812	COG3830	Belongs to the UPF0237 family
Clo1313_1817	COG4447	cellulose binding
Clo1313_1818	COG1191	sigma factor activity
Clo1313_1823	COG0393	Putative heavy-metal-binding
Clo1313_1824	COG1132	(ABC) transporter
Clo1313_1825	COG1132	(ABC) transporter
Clo1313_1826	COG1869	D-ribose catabolic process
Clo1313_1829	COG1172	Belongs to the binding-protein-dependent transport system permease family
Clo1313_1830	COG1129	ABC transporter
Clo1313_1831	COG1940	carbohydrate kinase activity
Clo1313_1832	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Clo1313_1833	COG1063	alcohol dehydrogenase
Clo1313_1838	COG0577	efflux transmembrane transporter activity
Clo1313_1838	COG1136	(ABC) transporter
Clo1313_1846	COG0519	Catalyzes the synthesis of GMP from XMP
Clo1313_1847	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Clo1313_1850	COG3328	transposase activity
Clo1313_1852	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Clo1313_1853	COG1691	(AIR) carboxylase
Clo1313_1854	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Clo1313_1857	COG3620	sequence-specific DNA binding
Clo1313_1858	COG0436	Aminotransferase
Clo1313_1859	COG1522	sequence-specific DNA binding
Clo1313_1862	COG3118	belongs to the thioredoxin family
Clo1313_1864	COG3328	transposase activity
Clo1313_1869	COG1379	DNA repair
Clo1313_1870	COG1924	4 iron, 4 sulfur cluster binding
Clo1313_1873	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Clo1313_1874	COG0681	Belongs to the peptidase S26 family
Clo1313_1875	COG0191	fructose-bisphosphate aldolase activity
Clo1313_1876	COG0205	6-phosphofructokinase activity
Clo1313_1878	COG0039	L-malate dehydrogenase activity
Clo1313_1879	COG0281	malic enzyme
Clo1313_1884	COG0784	Response regulator, receiver
Clo1313_1884	COG2205	protein histidine kinase activity
Clo1313_1891	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Clo1313_1896	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Clo1313_1897	COG1361	Conserved repeat domain
Clo1313_1897	COG2911	Protein conserved in bacteria
Clo1313_1897	COG3266	domain, Protein
Clo1313_1901	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Clo1313_1901	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Clo1313_1902	COG0525	valine-tRNA ligase activity
Clo1313_1904	COG1472	Belongs to the glycosyl hydrolase 3 family
Clo1313_1908	COG1376	ErfK ybiS ycfS ynhG family protein
Clo1313_1910	COG2133	pyrroloquinoline quinone binding
Clo1313_1910	COG5183	chlorophyll binding
Clo1313_1911	COG1191	sigma factor activity
Clo1313_1914	COG0542	response to heat
Clo1313_1917	COG3584	3D domain protein
Clo1313_1917	COG3583	domain protein
Clo1313_1918	COG0556	nucleotide-excision repair
Clo1313_1921	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Clo1313_1922	COG0187	DNA topoisomerase II activity
Clo1313_1926	COG2966	Psort location CytoplasmicMembrane, score
Clo1313_1927	COG2340	Cysteine-rich secretory protein family
Clo1313_1928	COG0534	Mate efflux family protein
Clo1313_1929	COG0840	transmembrane signaling receptor activity
Clo1313_1937	COG1331	Highly conserved protein containing a thioredoxin domain
Clo1313_1938	COG0460	homoserine dehydrogenase
Clo1313_1939	COG1199	ATP-dependent helicase activity
Clo1313_1940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Clo1313_1942	COG2205	protein histidine kinase activity
Clo1313_1944	COG0538	isocitrate dehydrogenase activity
Clo1313_1946	COG0667	Aldo Keto reductase
Clo1313_1947	COG0297	glycogen (starch) synthase activity
Clo1313_1950	COG0564	pseudouridine synthase activity
Clo1313_1951	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Clo1313_1951	COG0116	Belongs to the methyltransferase superfamily
Clo1313_1953	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Clo1313_1954	COG3459	Glycosyltransferase 36 associated
Clo1313_1955	COG4447	cellulose binding
Clo1313_1955	COG4733	cellulase activity
Clo1313_1956	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Clo1313_1956	COG2199	diguanylate cyclase activity
Clo1313_1957	COG1686	Belongs to the peptidase S11 family
Clo1313_1958	COG4733	cellulase activity
Clo1313_1958	COG4447	cellulose binding
Clo1313_1960	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Clo1313_1961	COG1191	sigma factor activity
Clo1313_1962	COG4447	cellulose binding
Clo1313_1963	COG0840	transmembrane signaling receptor activity
Clo1313_1964	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Clo1313_1967	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Clo1313_1969	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Clo1313_1971	COG4447	cellulose binding
Clo1313_1973	COG1609	Transcriptional regulator
Clo1313_1976	COG0714	Associated with various cellular activities
Clo1313_1979	COG1690	Belongs to the RtcB family
Clo1313_1982	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Clo1313_1983	COG3401	FG-GAP repeat protein
Clo1313_1985	COG2217	Heavy metal translocating P-type atpase
Clo1313_1986	COG3409	Peptidoglycan-binding domain 1 protein
Clo1313_1986	COG3773	Cell wall hydrolase
Clo1313_1990	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Clo1313_1992	COG0667	Aldo Keto reductase
Clo1313_1994	COG0318	PFAM AMP-dependent synthetase and ligase
Clo1313_1995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Clo1313_1997	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Clo1313_2005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Clo1313_2008	COG3328	transposase activity
Clo1313_2014	COG1408	metallophosphoesterase
Clo1313_2015	COG0166	Belongs to the GPI family
Clo1313_2017	COG0072	phenylalanine-tRNA ligase activity
Clo1313_2017	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Clo1313_2018	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Clo1313_2020	COG2723	6-phospho-beta-galactosidase activity
Clo1313_2022	COG2273	Hydrolase Family 16
Clo1313_2023	COG1609	Transcriptional regulator
Clo1313_2024	COG1215	transferase activity, transferring glycosyl groups
Clo1313_2033	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Clo1313_2034	COG0493	'glutamate synthase
Clo1313_2034	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Clo1313_2035	COG0069	glutamate synthase activity
Clo1313_2036	COG0067	glutamate synthase
Clo1313_2041	COG0475	glutathione-regulated potassium exporter activity
Clo1313_2042	COG2273	Hydrolase Family 16
Clo1313_2043	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Clo1313_2044	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Clo1313_2045	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Clo1313_2046	COG5401	PFAM Sporulation and spore germination
Clo1313_2047	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Clo1313_2048	COG0860	N-Acetylmuramoyl-L-alanine amidase
Clo1313_2050	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Clo1313_2051	COG2255	four-way junction helicase activity
Clo1313_2052	COG0632	four-way junction helicase activity
Clo1313_2053	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Clo1313_2054	COG0137	argininosuccinate synthase activity
Clo1313_2055	COG0165	Argininosuccinate lyase
Clo1313_2059	COG1368	sulfuric ester hydrolase activity
Clo1313_2060	COG0493	'glutamate synthase
Clo1313_2060	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Clo1313_2066	COG2201	protein-glutamate methylesterase activity
Clo1313_2067	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Clo1313_2069	COG1534	Rna-binding protein
Clo1313_2071	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Clo1313_2072	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Clo1313_2074	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Clo1313_2078	COG1470	cell adhesion involved in biofilm formation
Clo1313_2079	COG3906	Belongs to the UPF0473 family
Clo1313_2080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Clo1313_2081	COG0667	Aldo Keto reductase
Clo1313_2082	COG4472	Bacterial protein of unknown function (DUF965)
Clo1313_2083	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Clo1313_2085	COG1683	Conserved Protein
Clo1313_2086	COG0557	exoribonuclease II activity
Clo1313_2090	COG0148	phosphopyruvate hydratase activity
Clo1313_2091	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Clo1313_2091	COG2199	diguanylate cyclase activity
Clo1313_2092	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Clo1313_2093	COG0149	triose-phosphate isomerase activity
Clo1313_2094	COG0126	phosphoglycerate kinase activity
Clo1313_2099	COG0318	PFAM AMP-dependent synthetase and ligase
Clo1313_2100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Clo1313_2101	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Clo1313_2102	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Clo1313_2113	COG1366	Belongs to the anti-sigma-factor antagonist family
Clo1313_2114	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Clo1313_2115	COG1481	regulation of sporulation
Clo1313_2117	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Clo1313_2118	COG1660	Displays ATPase and GTPase activities
Clo1313_2119	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Clo1313_2120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Clo1313_2121	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Clo1313_2124	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Clo1313_2128	COG0432	Pfam Uncharacterised protein family UPF0047
Clo1313_2129	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Clo1313_2130	COG1979	alcohol dehydrogenase
Clo1313_2132	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Clo1313_2133	COG0517	IMP dehydrogenase activity
Clo1313_2133	COG1994	Peptidase M50
Clo1313_2134	COG0739	heme binding
Clo1313_2136	COG1803	Methylglyoxal synthase
Clo1313_2137	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Clo1313_2138	COG2894	cell division
Clo1313_2139	COG0850	regulation of cytokinetic process
Clo1313_2140	COG0768	penicillin binding
Clo1313_2143	COG1077	Cell shape determining protein MreB Mrl
Clo1313_2144	COG0424	maF-like protein
Clo1313_2149	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Clo1313_2150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Clo1313_2151	COG0835	chemotaxis
Clo1313_2161	COG4447	cellulose binding
Clo1313_2161	COG5297	Belongs to the glycosyl hydrolase family 6
Clo1313_2162	COG0017	Asparaginyl-tRNA synthetase
Clo1313_2163	COG2502	aspartate--ammonia ligase
Clo1313_2164	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Clo1313_2168	COG1283	sodium-dependent phosphate transmembrane transporter activity
Clo1313_2170	COG1368	sulfuric ester hydrolase activity
Clo1313_2171	COG1268	BioY protein
Clo1313_2172	COG0653	protein targeting
Clo1313_2173	COG4447	cellulose binding
Clo1313_2174	COG1191	sigma factor activity
Clo1313_2178	COG1649	PFAM Uncharacterised BCR, COG1649
Clo1313_2179	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Clo1313_2188	COG2382	esterase
Clo1313_2188	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_2188	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_2189	COG4733	cellulase activity
Clo1313_2189	COG4447	cellulose binding
Clo1313_2190	COG1160	GTP binding
Clo1313_2192	COG4447	cellulose binding
Clo1313_2192	COG4733	cellulase activity
Clo1313_2193	COG0840	transmembrane signaling receptor activity
Clo1313_2194	COG0835	chemotaxis
Clo1313_2195	COG0840	transmembrane signaling receptor activity
Clo1313_2196	COG0835	chemotaxis
Clo1313_2198	COG1151	hydroxylamine reductase activity
Clo1313_2202	COG4124	Belongs to the glycosyl hydrolase 26 family
Clo1313_2208	COG4106	trans-aconitate 2-methyltransferase activity
Clo1313_2209	COG2267	carboxylic ester hydrolase activity
Clo1313_2210	COG0156	8-amino-7-oxononanoate synthase activity
Clo1313_2211	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Clo1313_2212	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Clo1313_2216	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_2224	COG3328	transposase activity
Clo1313_2228	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Clo1313_2232	COG1595	DNA-templated transcription, initiation
Clo1313_2234	COG4124	Belongs to the glycosyl hydrolase 26 family
Clo1313_2234	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clo1313_2238	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Clo1313_2239	COG0717	Belongs to the dCTP deaminase family
Clo1313_2242	COG2409	Drug exporters of the RND superfamily
Clo1313_2244	COG0561	phosphatase activity
Clo1313_2247	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Clo1313_2247	COG0426	domain, Protein
Clo1313_2248	COG0494	nUDIX hydrolase
Clo1313_2250	COG0840	transmembrane signaling receptor activity
Clo1313_2255	COG1695	Transcriptional regulator
Clo1313_2259	COG0840	transmembrane signaling receptor activity
Clo1313_2260	COG0004	ammonium transporteR
Clo1313_2261	COG1132	(ABC) transporter
Clo1313_2262	COG1132	(ABC) transporter
Clo1313_2266	COG1361	Conserved repeat domain
Clo1313_2270	COG1393	Belongs to the ArsC family
Clo1313_2291	COG0577	efflux transmembrane transporter activity
Clo1313_2292	COG1136	(ABC) transporter
Clo1313_2293	COG2205	protein histidine kinase activity
Clo1313_2294	COG0745	RESPONSE REGULATOR receiver
Clo1313_2300	COG1131	(ABC) transporter
Clo1313_2302	COG3620	sequence-specific DNA binding
Clo1313_2304	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Clo1313_2305	COG0154	amidase activity
Clo1313_2307	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Clo1313_2312	COG1024	Enoyl-CoA hydratase
Clo1313_2314	COG4106	trans-aconitate 2-methyltransferase activity
Clo1313_2321	COG1464	Belongs to the NlpA lipoprotein family
Clo1313_2322	COG2011	ABC-type metal ion transport system permease component
Clo1313_2323	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Clo1313_2325	COG0626	cystathionine gamma-synthase activity
Clo1313_2326	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Clo1313_2334	COG0535	radical SAM domain protein
Clo1313_2335	COG2873	o-acetylhomoserine
Clo1313_2336	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Clo1313_2337	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clo1313_2339	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Clo1313_2341	COG0813	purine-nucleoside phosphorylase activity
Clo1313_2342	COG1744	ABC transporter substrate-binding protein PnrA-like
Clo1313_2343	COG1328	CTP reductase activity
Clo1313_2344	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Clo1313_2345	COG3845	ABC transporter
Clo1313_2346	COG4603	Belongs to the binding-protein-dependent transport system permease family
Clo1313_2347	COG1079	Belongs to the binding-protein-dependent transport system permease family
Clo1313_2348	COG0295	cytidine deaminase activity
Clo1313_2350	COG2207	Transcriptional regulator
Clo1313_2350	COG4753	response regulator
Clo1313_2353	COG3842	ATPase activity
Clo1313_2366	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Clo1313_2376	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Clo1313_2380	COG5632	N-Acetylmuramoyl-L-alanine amidase
Clo1313_2380	COG3409	Peptidoglycan-binding domain 1 protein
Clo1313_2396	COG0740	serine-type endopeptidase activity
Clo1313_2397	COG4695	Portal protein
Clo1313_2398	COG1802	Transcriptional regulator
Clo1313_2398	COG4626	Terminase
Clo1313_2414	COG1136	(ABC) transporter
Clo1313_2416	COG2205	protein histidine kinase activity
Clo1313_2417	COG0745	RESPONSE REGULATOR receiver
Clo1313_2426	COG1120	ATPase activity
Clo1313_2427	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Clo1313_2428	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Clo1313_2430	COG0739	heme binding
Clo1313_2434	COG0577	efflux transmembrane transporter activity
Clo1313_2436	COG1136	(ABC) transporter
Clo1313_2444	COG1592	Rubrerythrin
Clo1313_2445	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Clo1313_2446	COG1067	ATP-dependent peptidase activity
Clo1313_2447	COG0456	acetyltransferase
Clo1313_2448	COG1214	PFAM Peptidase M22, glycoprotease
Clo1313_2449	COG0802	atpase or kinase
Clo1313_2450	COG1228	amidohydrolase
Clo1313_2455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Clo1313_2456	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Clo1313_2458	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Clo1313_2459	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Clo1313_2461	COG1215	transferase activity, transferring glycosyl groups
Clo1313_2462	COG0542	response to heat
Clo1313_2463	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Clo1313_2464	COG3880	PFAM UvrB UvrC protein
Clo1313_2468	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Clo1313_2469	COG0287	Prephenate dehydrogenase
Clo1313_2470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Clo1313_2471	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Clo1313_2472	COG0488	(ABC) transporter
Clo1313_2474	COG1122	ATPase activity
Clo1313_2476	COG0310	cobalt ion transport
Clo1313_2477	COG0860	N-Acetylmuramoyl-L-alanine amidase
Clo1313_2478	COG0745	RESPONSE REGULATOR receiver
Clo1313_2483	COG1595	DNA-templated transcription, initiation
Clo1313_2486	COG0829	nickel cation binding
Clo1313_2487	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Clo1313_2490	COG0804	urea catabolic process
Clo1313_2491	COG0832	Belongs to the urease beta subunit family
Clo1313_2492	COG0831	urea catabolic process
Clo1313_2498	COG4753	response regulator
Clo1313_2498	COG2207	Transcriptional regulator
Clo1313_2500	COG4251	negative regulation of phosphorylation
Clo1313_2508	COG3328	transposase activity
Clo1313_2531	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Clo1313_2533	COG1606	tRNA processing
Clo1313_2535	COG1959	2 iron, 2 sulfur cluster binding
Clo1313_2536	COG1959	2 iron, 2 sulfur cluster binding
Clo1313_2537	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Clo1313_2538	COG5002	protein histidine kinase activity
Clo1313_2539	COG0745	RESPONSE REGULATOR receiver
Clo1313_2540	COG2217	Heavy metal translocating P-type atpase
Clo1313_2544	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Clo1313_2545	COG1278	Cold shock
Clo1313_2546	COG3695	enzyme binding
Clo1313_2549	COG3409	Peptidoglycan-binding domain 1 protein
Clo1313_2549	COG0793	Belongs to the peptidase S41A family
Clo1313_2551	COG2177	Part of the ABC transporter FtsEX involved in
Clo1313_2552	COG2884	Cell division ATP-binding protein ftsE
Clo1313_2553	COG3835	regulator
Clo1313_2554	COG3842	ATPase activity
Clo1313_2555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Clo1313_2556	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Clo1313_2558	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Clo1313_2559	COG0505	Belongs to the CarA family
Clo1313_2560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Clo1313_2561	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Clo1313_2564	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Clo1313_2568	COG1695	Transcriptional regulator
Clo1313_2569	COG1408	metallophosphoesterase
Clo1313_2572	COG1876	peptidase activity
Clo1313_2574	COG3328	transposase activity
Clo1313_2576	COG0726	polysaccharide deacetylase
Clo1313_2580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Clo1313_2580	COG0318	PFAM AMP-dependent synthetase and ligase
Clo1313_2580	COG3321	synthase
Clo1313_2580	COG0300	oxidoreductase activity
Clo1313_2580	COG1028	Short-chain dehydrogenase reductase Sdr
Clo1313_2589	COG5002	protein histidine kinase activity
Clo1313_2590	COG0745	RESPONSE REGULATOR receiver
Clo1313_2591	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Clo1313_2592	COG1982	Orn Lys Arg decarboxylase major
Clo1313_2593	COG1285	pathogenesis
Clo1313_2595	COG1695	Transcriptional regulator
Clo1313_2597	COG0504	CTP synthase activity
Clo1313_2601	COG3409	Peptidoglycan-binding domain 1 protein
Clo1313_2601	COG0793	Belongs to the peptidase S41A family
Clo1313_2604	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Clo1313_2606	COG0018	arginyl-trna synthetase
Clo1313_2608	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Clo1313_2609	COG1181	Belongs to the D-alanine--D-alanine ligase family
Clo1313_2610	COG2239	Acts as a magnesium transporter
Clo1313_2615	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Clo1313_2616	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Clo1313_2617	COG0492	ferredoxin-NADP+ reductase activity
Clo1313_2619	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Clo1313_2620	COG0785	Cytochrome C biogenesis protein
Clo1313_2626	COG2183	response to ionizing radiation
Clo1313_2631	COG2226	methyltransferase
Clo1313_2633	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Clo1313_2635	COG2382	esterase
Clo1313_2635	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_2635	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_2637	COG3634	alkyl hydroperoxide reductase activity
Clo1313_2638	COG0450	alkyl hydroperoxide reductase
Clo1313_2641	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Clo1313_2689	COG0515	serine threonine protein kinase
Clo1313_2689	COG0457	Tetratricopeptide repeat
Clo1313_2694	COG1074	ATP-dependent DNA helicase activity
Clo1313_2695	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Clo1313_2715	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Clo1313_2718	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Clo1313_2720	COG0697	spore germination
Clo1313_2723	COG0215	cysteine-tRNA ligase activity
Clo1313_2724	COG1045	serine acetyltransferase
Clo1313_2731	COG1473	amidohydrolase
Clo1313_2732	COG2155	Conserved Protein
Clo1313_2734	COG0217	transcriptional regulatory protein
Clo1313_2735	COG5002	protein histidine kinase activity
Clo1313_2737	COG1739	Uncharacterized protein family UPF0029
Clo1313_2738	COG0681	Belongs to the peptidase S26 family
Clo1313_2739	COG0494	nUDIX hydrolase
Clo1313_2740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Clo1313_2742	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Clo1313_2743	COG0756	dUTP diphosphatase activity
Clo1313_2744	COG0826	peptidase U32
Clo1313_2745	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Clo1313_2747	COG5297	Belongs to the glycosyl hydrolase family 6
Clo1313_2750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Clo1313_2751	COG3584	3D domain protein
Clo1313_2751	COG3583	domain protein
Clo1313_2753	COG0084	hydrolase, TatD family'
Clo1313_2754	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Clo1313_2754	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Clo1313_2756	COG0700	Nucleoside recognition
Clo1313_2757	COG2715	membrane protein required for spore maturation
Clo1313_2758	COG2002	toxin-antitoxin pair type II binding
Clo1313_2759	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Clo1313_2760	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Clo1313_2762	COG1774	PSP1 C-terminal conserved region
Clo1313_2763	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Clo1313_2764	COG1728	Protein conserved in bacteria
Clo1313_2766	COG1982	Orn Lys Arg decarboxylase major
Clo1313_2769	COG1136	(ABC) transporter
Clo1313_2772	COG5002	protein histidine kinase activity
Clo1313_2774	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Clo1313_2775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Clo1313_2777	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_2778	COG1191	sigma factor activity
Clo1313_2783	COG0395	ABC-type sugar transport system, permease component
Clo1313_2784	COG1175	transmembrane transport
Clo1313_2785	COG0714	Associated with various cellular activities
Clo1313_2794	COG3940	Belongs to the glycosyl hydrolase 43 family
Clo1313_2795	COG3940	Belongs to the glycosyl hydrolase 43 family
Clo1313_2798	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Clo1313_2800	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Clo1313_2801	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Clo1313_2802	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Clo1313_2812	COG1361	Conserved repeat domain
Clo1313_2820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Clo1313_2823	COG1773	rubredoxin
Clo1313_2828	COG1408	metallophosphoesterase
Clo1313_2831	COG0254	rRNA binding
Clo1313_2832	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Clo1313_2844	COG0038	chloride channel
Clo1313_2845	COG0037	tRNA processing
Clo1313_2847	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Clo1313_2848	COG1295	ribonuclease BN
Clo1313_2849	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Clo1313_2850	COG0629	single-stranded DNA binding
Clo1313_2851	COG0360	Binds together with S18 to 16S ribosomal RNA
Clo1313_2853	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Clo1313_2854	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Clo1313_2856	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_2856	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_2856	COG2382	esterase
Clo1313_2857	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_2858	COG2382	esterase
Clo1313_2858	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_2858	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_2859	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_2859	COG2382	esterase
Clo1313_2859	COG3693	PFAM glycoside hydrolase, family 10
Clo1313_2860	COG3507	Belongs to the glycosyl hydrolase 43 family
Clo1313_2861	COG3250	beta-galactosidase activity
Clo1313_2864	COG0789	Transcriptional regulator
Clo1313_2864	COG4978	Transcriptional regulator
Clo1313_2865	COG0577	efflux transmembrane transporter activity
Clo1313_2866	COG1136	(ABC) transporter
Clo1313_2867	COG5002	protein histidine kinase activity
Clo1313_2868	COG0745	RESPONSE REGULATOR receiver
Clo1313_2876	COG0302	gtp cyclohydrolase
Clo1313_2877	COG1181	Belongs to the D-alanine--D-alanine ligase family
Clo1313_2877	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Clo1313_2878	COG4242	Belongs to the peptidase S51 family
Clo1313_2880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Clo1313_2881	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Clo1313_2882	COG0473	3-isopropylmalate dehydrogenase activity
Clo1313_2883	COG0066	3-isopropylmalate dehydratase activity
Clo1313_2884	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Clo1313_2885	COG2207	Transcriptional regulator
Clo1313_2886	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Clo1313_2890	COG1516	flagellar protein fliS
Clo1313_2891	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Clo1313_2893	COG1088	dTDP-glucose 4,6-dehydratase activity
Clo1313_2894	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Clo1313_2897	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Clo1313_2900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Clo1313_2902	COG2089	acid synthase
Clo1313_2903	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Clo1313_2904	COG2226	methyltransferase
Clo1313_2905	COG1086	Polysaccharide biosynthesis protein
Clo1313_2909	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Clo1313_2910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Clo1313_2912	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Clo1313_2913	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Clo1313_2915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Clo1313_2916	COG4786	Flagellar basal body rod
Clo1313_2916	COG1256	bacterial-type flagellum assembly
Clo1313_2921	COG1040	competence protein
Clo1313_2922	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Clo1313_2924	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Clo1313_2926	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Clo1313_2927	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Clo1313_2928	COG0037	tRNA processing
Clo1313_2929	COG0305	Participates in initiation and elongation during chromosome replication
Clo1313_2930	COG0359	binds to the 23S rRNA
Clo1313_2931	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Clo1313_2933	COG0077	Prephenate dehydratase
Clo1313_2933	COG1605	Chorismate mutase
Clo1313_2935	COG1269	ATP hydrolysis coupled proton transport
Clo1313_2936	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Clo1313_2937	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
Clo1313_2940	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Clo1313_2941	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
Clo1313_2942	COG1394	ATPase activity, coupled to movement of substances
Clo1313_2943	COG0488	(ABC) transporter
Clo1313_2950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Clo1313_2953	COG0765	amino acid transport
Clo1313_2955	COG2201	protein-glutamate methylesterase activity
Clo1313_2956	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Clo1313_2958	COG0643	Histidine kinase
Clo1313_2958	COG2198	Histidine kinase
Clo1313_2959	COG0835	chemotaxis
Clo1313_2961	COG0582	viral genome integration into host DNA
Clo1313_2962	COG3708	Transcriptional regulator
Clo1313_2962	COG2207	Transcriptional regulator
Clo1313_2965	COG1131	(ABC) transporter
Clo1313_2969	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Clo1313_2970	COG1518	maintenance of DNA repeat elements
Clo1313_2978	COG1968	undecaprenyl-diphosphatase activity
Clo1313_2979	COG0534	Mate efflux family protein
Clo1313_2987	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Clo1313_2988	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Clo1313_2989	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Clo1313_2993	COG5002	protein histidine kinase activity
Clo1313_2994	COG0745	RESPONSE REGULATOR receiver
Clo1313_2999	COG0438	transferase activity, transferring glycosyl groups
Clo1313_3001	COG0438	transferase activity, transferring glycosyl groups
Clo1313_3007	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Clo1313_3008	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Clo1313_3011	COG1361	Conserved repeat domain
Clo1313_3013	COG3773	Cell wall hydrolase
Clo1313_3015	COG0517	IMP dehydrogenase activity
Clo1313_3018	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Clo1313_3019	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Clo1313_3022	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Clo1313_3023	COG4447	cellulose binding
Clo1313_3023	COG4733	cellulase activity
Clo1313_3024	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Clo1313_3025	COG1475	DNA binding
Clo1313_3026	COG0357	Ribosomal RNA small subunit methyltransferase G
Clo1313_3027	COG0445	tRNA wobble uridine modification
Clo1313_3028	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Clo1313_3029	COG1847	R3H domain protein
Clo1313_3030	COG0706	membrane insertase activity
Clo1313_3031	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Clo1313_3033	COG0230	Belongs to the bacterial ribosomal protein bL34 family