locus-tag	class	description
CLOST_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CLOST_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CLOST_0004	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CLOST_0005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CLOST_0006	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CLOST_0007	ENOG4105D58	Diguanylate phosphodiesterase
CLOST_0010	ENOG4105WN5	stage II sporulation protein
CLOST_0011	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
CLOST_0013	ENOG4105BZU	Histidine kinase
CLOST_0016	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CLOST_0018	ENOG4105C9M	aspartyl-trna synthetase
CLOST_0020	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CLOST_0021	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CLOST_0026	ENOG4105C84	Histidine ammonia-lyase
CLOST_0027	ENOG4105CGP	Urocanate hydratase
CLOST_0030	ENOG4108IJ8	ABC transporter
CLOST_0031	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_0032	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_0035	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CLOST_0037	ENOG4105E90	ABC transporter
CLOST_0038	ENOG4108IJ8	ABC transporter
CLOST_0039	ENOG4105E90	ABC transporter
CLOST_0041	ENOG4105CYW	agmatinase
CLOST_0042	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CLOST_0043	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
CLOST_0044	ENOG4105CXN	decarboxylase
CLOST_0045	ENOG4106M28	alanine racemase domain protein
CLOST_0047	ENOG4105G6Z	alkaline phosphatase
CLOST_0048	ENOG4105DJZ	UPF0182 protein
CLOST_0050	ENOG4108RAC	Rubrerythrin
CLOST_0051	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CLOST_0055	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CLOST_0056	ENOG4107SC7	Inner membrane transporter yjeM
CLOST_0071	ENOG4107Y2X	deaminase
CLOST_0073	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
CLOST_0075	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CLOST_0076	ENOG4105CKI	cobalamin synthesis protein
CLOST_0079	ENOG4108Q52	Methyltransferase cognate corrinoid protein
CLOST_0080	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CLOST_0085	ENOG4105C3U	ABC transporter
CLOST_0086	ENOG4108JQ7	(ABC) transporter
CLOST_0087	ENOG4106R87	Extracellular solute-binding protein, family 5
CLOST_0089	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CLOST_0090	ENOG4108UMI	ABC transporter, permease
CLOST_0091	ENOG4105D01	(LipO)protein
CLOST_0095	ENOG4105BZ1	(ABC) transporter
CLOST_0096	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
CLOST_0097	ENOG4105C5H	ABC transporter
CLOST_0098	ENOG4105CFP	Peptidase U32
CLOST_0099	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_0100	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
CLOST_0101	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
CLOST_0103	ENOG4108Z6B	deaminase
CLOST_0104	ENOG4105BZU	Histidine kinase
CLOST_0108	ENOG4105C6E	dna polymerase iii
CLOST_0109	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CLOST_0110	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CLOST_0112	ENOG4105KVH	Transcriptional regulator
CLOST_0120	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
CLOST_0123	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_0124	ENOG4105CJW	magnesium transporter
CLOST_0125	ENOG4105BZU	Histidine kinase
CLOST_0126	ENOG4105BZU	Histidine kinase
CLOST_0128	ENOG4108115	UPF0145 protein
CLOST_0130	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_0131	ENOG4105BZU	Histidine kinase
CLOST_0133	ENOG4105C5H	ABC transporter
CLOST_0134	ENOG4105C1J	atp-dependent rna helicase
CLOST_0136	ENOG4105C8Y	Acetylornithine aminotransferase
CLOST_0137	ENOG4105CAS	nag kinase
CLOST_0138	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CLOST_0139	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CLOST_0141	ENOG4105CDH	Citrulline--aspartate ligase
CLOST_0143	ENOG4105VC4	domain protein
CLOST_0144	ENOG4105C3R	Methionine synthase
CLOST_0146	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_0147	ENOG4105CPI	Metal Dependent Phosphohydrolase
CLOST_0149	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CLOST_0151	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_0152	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CLOST_0153	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CLOST_0156	ENOG4108RMU	ferritin dps family protein
CLOST_0157	ENOG4108UYE	Lactoylglutathione lyase
CLOST_0159	ENOG41066A3	ATP guanido phosphotransferase
CLOST_0161	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CLOST_0163	ENOG4105CTP	PilT protein domain protein
CLOST_0167	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CLOST_0171	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CLOST_0174	ENOG4105CG3	alpha amylase, catalytic region
CLOST_0175	ENOG4105C98	muts2 protein
CLOST_0176	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
CLOST_0177	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CLOST_0178	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CLOST_0181	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CLOST_0184	ENOG4107QHF	type ii secretion system protein e
CLOST_0185	ENOG4105CZX	twitching motility protein
CLOST_0195	ENOG4105CHR	reductase
CLOST_0196	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CLOST_0198	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
CLOST_0200	ENOG4108JUB	Transcriptional regulator
CLOST_0204	ENOG4107RE7	phosphate butyryltransferase
CLOST_0208	ENOG4105CKM	Branched-chain carboxylic acid kinase
CLOST_0209	ENOG4105E4P	ATPase (AAA
CLOST_0210	ENOG4105E4C	Lytic transglycosylase catalytic
CLOST_0211	ENOG4105EHZ	conserved protein UCP016719
CLOST_0213	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CLOST_0217	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CLOST_0220	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CLOST_0222	ENOG4105HA9	of methanol dehydrogenase type
CLOST_0223	ENOG4108V0P	LemA family
CLOST_0224	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CLOST_0225	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CLOST_0226	ENOG4105EPR	degv family
CLOST_0230	ENOG4105DTQ	mandelate racemase muconate lactonizing
CLOST_0231	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CLOST_0232	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
CLOST_0234	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
CLOST_0235	ENOG4108KGH	TRANSCRIPTIONal
CLOST_0237	ENOG4105E5W	Transporter
CLOST_0240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CLOST_0241	ENOG4105BZU	Histidine kinase
CLOST_0242	ENOG4105M3W	utilization protein
CLOST_0243	ENOG4105KTW	ethanolamine utilization protein
CLOST_0246	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
CLOST_0247	ENOG4105CPD	ethanolamine ammonia-lyase
CLOST_0248	ENOG4107FQ9	ethanolamine ammonia-lyase
CLOST_0249	ENOG4106D67	ethanolamine utilization protein
CLOST_0250	ENOG4105KNY	Microcompartments protein
CLOST_0251	ENOG4108EKI	Dehydrogenase
CLOST_0252	ENOG4105KNY	Microcompartments protein
CLOST_0254	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
CLOST_0256	ENOG4105ENY	Ethanolamine utilization protein eutH
CLOST_0257	ENOG4105NDK	ethanolamine utilization protein
CLOST_0258	ENOG4107RWI	ethanolamine utilization protein eutJ
CLOST_0259	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CLOST_0260	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CLOST_0262	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CLOST_0263	ENOG4108JU5	Magnesium and cobalt efflux protein
CLOST_0268	ENOG4107PPM	cobalt chelatase
CLOST_0269	ENOG4108V4M	Cobalt abc transporter
CLOST_0270	ENOG4108JJB	ABC transporter
CLOST_0274	ENOG4105CD3	dihydroorotase
CLOST_0276	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
CLOST_0277	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
CLOST_0278	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CLOST_0281	ENOG4105CGH	5'-nucleotidase
CLOST_0282	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CLOST_0284	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CLOST_0285	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CLOST_0286	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CLOST_0287	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
CLOST_0288	ENOG4105C8M	UPF0272 protein
CLOST_0289	ENOG4105CPN	adenine deaminase
CLOST_0290	ENOG4105BZ1	(ABC) transporter
CLOST_0292	ENOG4105BZ1	(ABC) transporter
CLOST_0296	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CLOST_0297	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CLOST_0300	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
CLOST_0306	ENOG4105MU5	relaxase mobilization nuclease domain protein
CLOST_0311	ENOG4105CB5	ATP-dependent DNA helicase recG
CLOST_0320	ENOG4108V0P	LemA family
CLOST_0322	ENOG4105KY5	gCN5-related N-acetyltransferase
CLOST_0323	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CLOST_0328	ENOG4105CGZ	zinc metallopeptidase
CLOST_0329	ENOG4108Z0Z	intracellular protease Pfpi family
CLOST_0331	ENOG4105EC8	Methyl-accepting chemotaxis
CLOST_0332	ENOG4105C7N	Xanthine uracil vitamin C permease
CLOST_0333	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CLOST_0334	ENOG4105C8V	SAICAR synthetase
CLOST_0336	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CLOST_0337	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CLOST_0338	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CLOST_0339	ENOG4107QNG	Phosphoribosylglycinamide synthetase
CLOST_0340	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_0341	ENOG4108IY2	MazG family
CLOST_0342	ENOG4105K70	DNA-binding protein
CLOST_0343	ENOG41082I2	s4 domain protein
CLOST_0345	ENOG4105C9X	ppx gppa phosphatase
CLOST_0350	ENOG4106AKK	s-layer domain-containing protein
CLOST_0359	ENOG4105D3Q	Sugar transferase
CLOST_0360	ENOG4105CAQ	asparagine synthetase
CLOST_0364	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CLOST_0365	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
CLOST_0367	ENOG4105D2T	synthase
CLOST_0368	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
CLOST_0369	ENOG4105F0R	Cytidylyltransferase
CLOST_0370	ENOG4105CJR	Integral membrane protein (MviN
CLOST_0375	ENOG4105DIH	basic membrane
CLOST_0376	ENOG4108JQ9	ABC transporter
CLOST_0377	ENOG4105UIB	(ABC) transporter
CLOST_0381	ENOG4108I5U	Uridine phosphorylase
CLOST_0384	ENOG4105F7F	Chaperone
CLOST_0386	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CLOST_0387	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
CLOST_0395	ENOG4105C7B	Threonine dehydratase
CLOST_0396	ENOG4107R7I	amino acid
CLOST_0398	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
CLOST_0399	ENOG4108K0B	C-di-gmp phosphodiesterase
CLOST_0404	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_0405	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_0406	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_0407	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_0408	ENOG4105VDW	Csbd family
CLOST_0409	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CLOST_0410	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CLOST_0411	ENOG4108R6K	riboflavin synthase, subunit alpha
CLOST_0412	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CLOST_0413	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CLOST_0414	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CLOST_0415	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CLOST_0417	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CLOST_0418	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CLOST_0420	ENOG41067TZ	transcriptional regulator, MarR family
CLOST_0423	ENOG4105D0S	secretion protein (HlyD
CLOST_0426	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CLOST_0427	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CLOST_0428	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLOST_0429	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLOST_0430	ENOG4105CHM	Aminotransferase
CLOST_0431	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CLOST_0432	ENOG4108MXK	alkaline phosphatase isozyme conversion
CLOST_0434	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CLOST_0443	ENOG4108UW5	maltose o-acetyltransferase
CLOST_0444	ENOG4105CKK	Glycosyl transferase, family 2
CLOST_0450	ENOG4105K4H	Nlp p60 protein
CLOST_0452	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CLOST_0453	ENOG4107RBB	ABC transporter, permease
CLOST_0455	ENOG4105MKU	Transcriptional regulator
CLOST_0456	ENOG4105Y49	secretion protein, HlyD family
CLOST_0460	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CLOST_0461	ENOG4105RYY	domain protein
CLOST_0462	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CLOST_0463	ENOG4105DAP	Nicotinate phosphoribosyltransferase
CLOST_0464	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CLOST_0465	ENOG4105F8V	Hydrolase, tatD family
CLOST_0468	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CLOST_0469	ENOG4105DFU	Cell wall formation (By similarity)
CLOST_0470	ENOG4105DFT	pur operon repressor
CLOST_0471	ENOG4105K4W	Could be involved in septation (By similarity)
CLOST_0472	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CLOST_0473	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CLOST_0474	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CLOST_0475	ENOG4108JA2	transcriptioN-repair coupling factor
CLOST_0476	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CLOST_0477	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CLOST_0478	ENOG4105CKP	Polysaccharide Biosynthesis Protein
CLOST_0484	ENOG4105C8B	TIGR00159 family
CLOST_0486	ENOG4105CKM	Branched-chain carboxylic acid kinase
CLOST_0487	ENOG4107RE7	phosphate butyryltransferase
CLOST_0488	ENOG4105CKM	Branched-chain carboxylic acid kinase
CLOST_0491	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CLOST_0494	ENOG4108JYZ	YitT family
CLOST_0497	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CLOST_0498	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CLOST_0500	ENOG4105CPI	Metal Dependent Phosphohydrolase
CLOST_0504	ENOG4105H0Z	Hemerythrin HHE cation binding domain protein
CLOST_0505	ENOG4105CJP	fad dependent oxidoreductase
CLOST_0507	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CLOST_0516	ENOG4108NEV	two component transcriptional regulator, LytTR family
CLOST_0520	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CLOST_0521	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CLOST_0523	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CLOST_0524	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CLOST_0527	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CLOST_0528	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CLOST_0531	ENOG4105C4B	ABC transporter, permease
CLOST_0532	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CLOST_0535	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CLOST_0536	ENOG4105KME	endoribonuclease L-psp
CLOST_0537	ENOG4105D9R	oxidoreductase
CLOST_0538	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CLOST_0539	ENOG4105C2F	Histidine kinase
CLOST_0540	ENOG4108NEV	two component transcriptional regulator, LytTR family
CLOST_0541	ENOG4105DFW	ABC transporter
CLOST_0542	ENOG4105DFW	ABC transporter
CLOST_0544	ENOG4107RNG	ABC transporter
CLOST_0546	ENOG4108UQV	Membrane
CLOST_0547	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CLOST_0549	ENOG4105DKQ	ROK family
CLOST_0552	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CLOST_0553	ENOG4108NRW	Phospholipase, patatin family
CLOST_0555	ENOG4105C4R	Atp-dependent dna helicase
CLOST_0556	ENOG4105DFM	M18 family aminopeptidase
CLOST_0560	ENOG4108YG4	
CLOST_0566	ENOG4105DZ6	Band 7 protein
CLOST_0567	ENOG4105C59	p-type ATPase
CLOST_0569	ENOG4107ZE5	PPIases accelerate the folding of proteins
CLOST_0570	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CLOST_0573	ENOG4105CBD	Diacylglycerol kinase
CLOST_0574	ENOG4105BZU	Histidine kinase
CLOST_0576	ENOG4105UQX	Mate efflux family protein
CLOST_0579	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CLOST_0580	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CLOST_0581	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CLOST_0582	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CLOST_0584	ENOG4108JQ7	(ABC) transporter
CLOST_0585	ENOG4108J59	Extracellular solute-binding protein, family 5
CLOST_0586	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CLOST_0589	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CLOST_0590	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CLOST_0591	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CLOST_0593	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CLOST_0594	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CLOST_0597	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
CLOST_0599	ENOG4105DZ0	fad dependent oxidoreductase
CLOST_0601	ENOG4107QYV	phosphohexose isomerase
CLOST_0603	ENOG4107T3P	ABC, transporter
CLOST_0604	ENOG4105CK2	sodium dicarboxylate symporter
CLOST_0605	ENOG4105FDK	ABC transporter
CLOST_0606	ENOG4105FAV	ABC, transporter
CLOST_0608	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_0609	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
CLOST_0610	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
CLOST_0612	ENOG4105C8U	phosphate abc transporter
CLOST_0613	ENOG4105E2Z	phosphate ABC transporter (Permease
CLOST_0614	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CLOST_0615	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CLOST_0622	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CLOST_0623	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CLOST_0628	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CLOST_0629	ENOG4105CH2	amidohydrolase
CLOST_0636	ENOG4105D7V	transposase
CLOST_0637	ENOG4108D32	Methyltransferase
CLOST_0638	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CLOST_0639	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CLOST_0640	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CLOST_0643	ENOG4105BZA	Phosphoglycerate kinase
CLOST_0644	ENOG4105CP7	Triose-phosphate isomerase
CLOST_0646	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CLOST_0648	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CLOST_0649	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
CLOST_0651	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CLOST_0652	ENOG4105CQC	Prephenate dehydratase
CLOST_0654	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CLOST_0655	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CLOST_0657	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CLOST_0659	ENOG4105BZU	Histidine kinase
CLOST_0661	ENOG4108JUB	Transcriptional regulator
CLOST_0662	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CLOST_0663	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CLOST_0664	ENOG4105DYB	Isoaspartyl dipeptidase
CLOST_0665	ENOG4105BZU	Histidine kinase
CLOST_0667	ENOG4105EPR	degv family
CLOST_0669	ENOG4105BZU	Histidine kinase
CLOST_0670	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_0671	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CLOST_0672	ENOG4107EDW	L-fucose operon activator
CLOST_0674	ENOG4108EKI	Dehydrogenase
CLOST_0676	ENOG4105KNY	Microcompartments protein
CLOST_0678	ENOG4105KNY	Microcompartments protein
CLOST_0679	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
CLOST_0680	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CLOST_0682	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CLOST_0686	ENOG4105C2J	ABC transporter
CLOST_0687	ENOG4108HWW	ABC transporter
CLOST_0688	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
CLOST_0689	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CLOST_0693	ENOG4105D7N	magnesium and cobalt transport protein CorA
CLOST_0700	ENOG4107G43	radical SAM domain protein
CLOST_0702	ENOG4108I0C	methyltransferase
CLOST_0704	ENOG4105EUB	pirin domain protein
CLOST_0707	ENOG4105EXU	Membrane
CLOST_0709	ENOG4105VYW	UPF0251 protein
CLOST_0712	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CLOST_0713	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CLOST_0714	ENOG4108IGT	Dipeptidase
CLOST_0715	ENOG41086D8	Transcriptional regulator
CLOST_0723	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CLOST_0724	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CLOST_0725	ENOG41084HI	prevent-host-death family
CLOST_0728	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_0747	ENOG4105EYH	Exonuclease
CLOST_0748	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CLOST_0750	ENOG4105K63	Thioredoxin
CLOST_0751	ENOG4105BZU	Histidine kinase
CLOST_0757	ENOG4105CKM	Branched-chain carboxylic acid kinase
CLOST_0761	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
CLOST_0763	ENOG4107S21	permease
CLOST_0764	ENOG41082YX	Transcriptional regulator, arsr family
CLOST_0768	ENOG4105D6J	arsenicaL-resistance protein
CLOST_0770	ENOG4105ETE	Transcriptional regulator (LacI family
CLOST_0771	ENOG4105C2J	ABC transporter
CLOST_0772	ENOG4105CNN	ABC, transporter
CLOST_0774	ENOG4105CPQ	Dehydrogenase
CLOST_0775	ENOG4105CMG	Carbohydrate kinase
CLOST_0777	ENOG4105VNH	ABC transporter solute-binding protein
CLOST_0778	ENOG4105F38	ABC transporter, permease
CLOST_0780	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CLOST_0782	ENOG4108KCW	iron-sulfur cluster binding
CLOST_0783	ENOG4108N5C	SNARE associated Golgi protein-related protein
CLOST_0787	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CLOST_0790	ENOG4105BZ1	(ABC) transporter
CLOST_0791	ENOG4105BZ1	(ABC) transporter
CLOST_0798	ENOG4105BZU	Histidine kinase
CLOST_0801	ENOG4108IFG	nitrite reductase, (NAD(P)H)
CLOST_0802	ENOG4105D0C	transport protein
CLOST_0803	ENOG4105DC7	peptidase M24
CLOST_0804	ENOG4105CI2	imidazolone-5-propionate hydrolase
CLOST_0823	ENOG4105CXN	decarboxylase
CLOST_0824	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CLOST_0827	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
CLOST_0830	ENOG4108RC0	Electron transport protein
CLOST_0831	ENOG4105BZU	Histidine kinase
CLOST_0833	ENOG4105EB2	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CLOST_0836	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CLOST_0837	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CLOST_0838	ENOG4108XIB	electron transport protein ysaA
CLOST_0839	ENOG4107QHI	-hydrogenase
CLOST_0840	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
CLOST_0843	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CLOST_0845	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CLOST_0847	ENOG4107QW8	radical SAM domain protein
CLOST_0850	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CLOST_0855	ENOG4105DCI	Phosphohydrolase
CLOST_0861	ENOG4105CZX	twitching motility protein
CLOST_0863	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CLOST_0865	ENOG4105VEQ	Cold shock protein
CLOST_0866	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CLOST_0867	ENOG410902V	Modulates RecA activity (By similarity)
CLOST_0868	ENOG4105CI3	gtp-binding protein typa
CLOST_0869	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CLOST_0870	ENOG4105BZU	Histidine kinase
CLOST_0874	ENOG4108IJ6	ABC transporter
CLOST_0876	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CLOST_0879	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CLOST_0881	ENOG4108JQ7	(ABC) transporter
CLOST_0882	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_0883	ENOG4105DR5	peptidase
CLOST_0885	ENOG4105BZU	Histidine kinase
CLOST_0886	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CLOST_0889	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CLOST_0890	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CLOST_0891	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CLOST_0893	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
CLOST_0894	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CLOST_0895	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CLOST_0896	ENOG4105EA8	2-Nitropropane dioxygenase
CLOST_0897	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CLOST_0898	ENOG4105CHR	reductase
CLOST_0899	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CLOST_0900	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CLOST_0901	ENOG4105D6E	homoserine dehydrogenase
CLOST_0904	ENOG4105C9X	ppx gppa phosphatase
CLOST_0906	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CLOST_0907	ENOG4107QHI	-hydrogenase
CLOST_0908	ENOG4107QIZ	NADH dehydrogenase
CLOST_0909	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
CLOST_0910	ENOG4108IFG	nitrite reductase, (NAD(P)H)
CLOST_0912	ENOG4108YBP	pseudouridine synthase
CLOST_0915	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CLOST_0916	ENOG4105N5T	Radical SAM Protein
CLOST_0922	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
CLOST_0923	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
CLOST_0924	ENOG4105FCD	Major Facilitator
CLOST_0925	ENOG4105W1Y	Transcriptional regulator
CLOST_0926	ENOG4105CEU	Arginine dihydrolase
CLOST_0927	ENOG4105DBV	ornithine carbamoyltransferase
CLOST_0928	ENOG4105C5B	carbamate kinase
CLOST_0931	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CLOST_0932	ENOG4105DRR	Transcriptional regulator, GntR family
CLOST_0933	ENOG4105CPF	Cell wall formation (By similarity)
CLOST_0934	ENOG4105CPF	Cell wall formation (By similarity)
CLOST_0936	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CLOST_0937	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CLOST_0939	ENOG4105D5P	Methylmalonyl-coA mutase
CLOST_0942	ENOG4107QX3	carboxylase
CLOST_0944	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
CLOST_0945	ENOG4105D9Q	decarboxylase (Beta subunit)
CLOST_0947	ENOG4105KXX	peptidase s58 dmpa
CLOST_0949	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CLOST_0951	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CLOST_0952	ENOG4105CRK	lysyL-tRNA synthetase
CLOST_0955	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CLOST_0956	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CLOST_0964	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CLOST_0965	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CLOST_0967	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CLOST_0969	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CLOST_0972	ENOG4105C1J	atp-dependent rna helicase
CLOST_0976	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CLOST_0977	ENOG4105K56	Transcriptional regulator
CLOST_0978	ENOG4108V06	Glutathione peroxidase
CLOST_0981	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CLOST_0982	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CLOST_0985	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CLOST_0986	ENOG4105JZC	GHMP kinase
CLOST_0987	ENOG41081F0	Precorrin-8x methylmutase
CLOST_0988	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
CLOST_0989	ENOG4108DR9	Cobalt-precorrin-6Y C(5)-methyltransferase
CLOST_0990	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
CLOST_0991	ENOG4105DVK	Precorrin-2 c20-methyltransferase
CLOST_0992	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
CLOST_0993	ENOG4108P62	biosynthesis protein (CbiG)
CLOST_0994	ENOG4105E4R	Precorrin-3B C17-methyltransferase
CLOST_0996	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CLOST_0997	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CLOST_0998	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CLOST_1000	ENOG4105D52	delta-aminolevulinic acid dehydratase
CLOST_1001	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CLOST_1006	ENOG4105K95	(LipO)protein
CLOST_1007	ENOG4105CPN	adenine deaminase
CLOST_1012	ENOG4108J9M	Transporter
CLOST_1013	ENOG4108594	Permease of the drug metabolite transporter
CLOST_1015	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CLOST_1018	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CLOST_1019	ENOG4105EB3	Histidine kinase
CLOST_1021	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CLOST_1023	ENOG4108Z4K	mutator MutT protein
CLOST_1026	ENOG4108VW9	Membrane
CLOST_1027	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CLOST_1036	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CLOST_1041	ENOG4105CUT	histidyl-tRNA synthetase
CLOST_1043	ENOG4108IMY	Transcriptional regulator
CLOST_1044	ENOG4105C5X	domain protein
CLOST_1047	ENOG4105BZU	Histidine kinase
CLOST_1051	ENOG4108ESY	Metal dependent phosphohydrolase
CLOST_1052	ENOG4108UVJ	appr-1-p processing domain protein
CLOST_1059	ENOG4105C94	Transporter
CLOST_1068	ENOG4106DSS	Tartrate dehydratase subunit alpha
CLOST_1072	ENOG4108Z86	Glutamine amidotransferase
CLOST_1075	ENOG4105D22	carbon starvation protein
CLOST_1077	ENOG4105DY9	regulatoR
CLOST_1078	ENOG4108HRK	Histidine kinase
CLOST_1080	ENOG4108VW9	Membrane
CLOST_1081	ENOG4108JUB	Transcriptional regulator
CLOST_1083	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CLOST_1084	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CLOST_1086	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
CLOST_1087	ENOG4105ECY	inositol monophosphatase
CLOST_1089	ENOG41074CX	linocin_m18 bacteriocin protein
CLOST_1090	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CLOST_1093	ENOG4105C3F	Signal peptidase i
CLOST_1095	ENOG4105C22	threonyL-tRNA synthetase
CLOST_1098	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CLOST_1099	ENOG4105CSM	endonuclease III
CLOST_1100	ENOG41073R8	VanW family
CLOST_1101	ENOG4108YZT	Adenosylcobinamide kinase
CLOST_1102	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CLOST_1103	ENOG4107TB6	phosphoglycerate mutase
CLOST_1104	ENOG410667J	hydrolase
CLOST_1105	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CLOST_1106	ENOG4105EPR	degv family
CLOST_1109	ENOG41080XV	Thioredoxin
CLOST_1110	ENOG4105EZ5	reductase
CLOST_1117	ENOG4105DIH	basic membrane
CLOST_1118	ENOG4108JQ9	ABC transporter
CLOST_1119	ENOG4108JQ9	ABC transporter
CLOST_1120	ENOG4105UIB	(ABC) transporter
CLOST_1123	ENOG4107QP7	CoA-transferase subunit A
CLOST_1127	ENOG4105C22	threonyL-tRNA synthetase
CLOST_1129	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CLOST_1130	ENOG4105VJV	50s ribosomal protein L35
CLOST_1131	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CLOST_1132	ENOG4105E39	Enoyl-CoA hydratase
CLOST_1133	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CLOST_1134	ENOG4105CHU	acetyl-coa acetyltransferase
CLOST_1135	ENOG4105C1G	acyl-Coa dehydrogenase
CLOST_1136	ENOG4105BZJ	Electron transfer flavoprotein
CLOST_1137	ENOG4105C10	Electron transfer flavoprotein
CLOST_1138	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_1139	ENOG4105CZN	Potassium uptake protein
CLOST_1140	ENOG4107ZYR	domain protein
CLOST_1141	ENOG4108RWN	rrna methyltransferase
CLOST_1142	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CLOST_1143	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CLOST_1144	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CLOST_1145	ENOG4105CFP	Peptidase U32
CLOST_1146	ENOG4105C98	muts2 protein
CLOST_1148	ENOG41090R7	Ferric uptake
CLOST_1149	ENOG4105C75	arginyL-tRNA synthetase
CLOST_1155	ENOG4107RE7	phosphate butyryltransferase
CLOST_1158	ENOG4105DQU	oxidoreductase, subunit beta
CLOST_1160	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
CLOST_1161	ENOG41080XS	Cobyrinic acid ac-diamide synthase
CLOST_1162	ENOG4105CKU	formyltetrahydrofolate synthetase
CLOST_1163	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
CLOST_1168	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
CLOST_1169	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
CLOST_1171	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
CLOST_1172	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CLOST_1179	ENOG4105C4R	Atp-dependent dna helicase
CLOST_1187	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CLOST_1190	ENOG4108U5J	'-nucleotidase
CLOST_1192	ENOG4105D2N	Aldolase
CLOST_1193	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CLOST_1195	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CLOST_1196	ENOG4108HFV	
CLOST_1198	ENOG4105PTM	secreted protein
CLOST_1199	ENOG4107XJU	UPF0178 protein
CLOST_1200	ENOG4105FDP	GntR family transcriptional regulator
CLOST_1201	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CLOST_1202	ENOG4105F38	ABC transporter, permease
CLOST_1203	ENOG4105D38	putrescine abc transporter
CLOST_1204	ENOG4107RUE	extracellular solute-binding protein family 1
CLOST_1206	ENOG4108KPW	sugar kinase
CLOST_1208	ENOG4105DEU	major facilitator superfamily
CLOST_1214	ENOG4105ETE	Transcriptional regulator (LacI family
CLOST_1215	ENOG4108IUJ	4-alpha-glucanotransferase
CLOST_1217	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CLOST_1219	ENOG4107QTZ	amino acid
CLOST_1220	ENOG41080E8	Transcriptional regulator, Spx MgsR family
CLOST_1222	ENOG4105CHM	Aminotransferase
CLOST_1227	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CLOST_1228	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CLOST_1229	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CLOST_1231	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CLOST_1232	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CLOST_1233	ENOG4105CXI	aluminum resistance protein
CLOST_1235	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CLOST_1237	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CLOST_1238	ENOG4105C83	adenylosuccinate lyase
CLOST_1241	ENOG4105FAE	von Willebrand factor, type A
CLOST_1243	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CLOST_1245	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CLOST_1248	ENOG4105VTR	Integrase
CLOST_1256	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CLOST_1268	ENOG4105C7H	Helicase, RecD TraA family
CLOST_1282	ENOG4105CCS	Glutamate formiminotransferase
CLOST_1283	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
CLOST_1284	ENOG4105CI2	imidazolone-5-propionate hydrolase
CLOST_1285	ENOG4105DWU	Membrane
CLOST_1288	ENOG4106M28	alanine racemase domain protein
CLOST_1290	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
CLOST_1291	ENOG4105KIJ	D-ornithine aminomutase S component
CLOST_1292	ENOG4107RH1	pyridoxal-5'-phosphate-dependent protein beta subunit
CLOST_1293	ENOG4105Z5Q	
CLOST_1294	ENOG4108KR4	dihydrodipicolinate reductase
CLOST_1295	ENOG4108JUB	Transcriptional regulator
CLOST_1296	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CLOST_1300	ENOG4105C9M	aspartyl-trna synthetase
CLOST_1301	ENOG4105CUT	histidyl-tRNA synthetase
CLOST_1302	ENOG4105D4P	Coproporphyrinogen iii oxidase
CLOST_1303	ENOG4105C5X	domain protein
CLOST_1304	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CLOST_1305	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CLOST_1306	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CLOST_1307	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CLOST_1309	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CLOST_1310	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CLOST_1311	ENOG4105VIE	preprotein translocase, subunit YajC
CLOST_1312	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CLOST_1313	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CLOST_1314	ENOG4105JFG	SpoIID LytB domain protein
CLOST_1316	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CLOST_1317	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CLOST_1318	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CLOST_1319	ENOG4105C3S	Mate efflux family protein
CLOST_1320	ENOG4108U05	Transcriptional regulator
CLOST_1321	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CLOST_1322	ENOG4105CDY	transcriptional regulatory protein
CLOST_1323	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
CLOST_1325	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CLOST_1327	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CLOST_1329	ENOG4105CFP	Peptidase U32
CLOST_1330	ENOG4108VQJ	O-methyltransferase
CLOST_1337	ENOG4105CKK	Glycosyl transferase, family 2
CLOST_1340	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CLOST_1341	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
CLOST_1342	ENOG4105DX0	Hemolysin A
CLOST_1343	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CLOST_1348	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CLOST_1349	ENOG4105M7K	Involved in the transcription termination process (By similarity)
CLOST_1350	ENOG4108ZSR	alkaline shock protein
CLOST_1351	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CLOST_1352	ENOG41067VY	50S ribosomal protein L32
CLOST_1354	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CLOST_1356	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CLOST_1357	ENOG4105EM7	Selenocysteine-specific translation elongation factor
CLOST_1360	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CLOST_1361	ENOG4105KQC	Competence protein
CLOST_1362	ENOG4105DZ1	carboxypeptidase
CLOST_1364	ENOG4105EJQ	L-serine dehydratase
CLOST_1367	ENOG4108KGH	TRANSCRIPTIONal
CLOST_1368	ENOG4108WF2	Metal Dependent Phosphohydrolase
CLOST_1369	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CLOST_1371	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLOST_1372	ENOG4105K46	50S ribosomal protein l27
CLOST_1374	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CLOST_1375	ENOG4105C03	ribonuclease
CLOST_1378	ENOG4107CHF	5,6-aminomutase beta subunit
CLOST_1379	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
CLOST_1380	ENOG4105C98	muts2 protein
CLOST_1382	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CLOST_1383	ENOG4105FRY	Dehydrogenase
CLOST_1384	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
CLOST_1385	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
CLOST_1386	ENOG4108Z5K	methylglyoxal synthase
CLOST_1387	ENOG4105CNI	cell division protein FtsW
CLOST_1388	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CLOST_1390	ENOG4107QMS	site-determining protein
CLOST_1391	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CLOST_1395	ENOG4105W5Q	DNA repair protein (RadC
CLOST_1396	ENOG4108Z03	MAF-like protein
CLOST_1397	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
CLOST_1398	ENOG4105DGN	Electron transport complex
CLOST_1399	ENOG4105DZB	Electron transport complex
CLOST_1400	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
CLOST_1401	ENOG4105D6A	Electron transport complex
CLOST_1402	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CLOST_1403	ENOG4108QBX	(LipO)protein
CLOST_1405	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CLOST_1406	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CLOST_1407	ENOG4105C2M	dna polymerase I
CLOST_1413	ENOG4105CFH	Aspartokinase
CLOST_1415	ENOG4105CJ2	(LipO)protein
CLOST_1419	ENOG4105CEP	NADH dehydrogenase
CLOST_1421	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CLOST_1422	ENOG4105C01	Dihydroxy-acid dehydratase
CLOST_1423	ENOG4105C7K	acetolactate synthase
CLOST_1425	ENOG41085GJ	domain protein
CLOST_1427	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
CLOST_1431	ENOG4105CKK	Glycosyl transferase, family 2
CLOST_1432	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CLOST_1434	ENOG4105C5Q	Transcriptional regulator
CLOST_1435	ENOG41066VF	YeeE YedE family protein
CLOST_1437	ENOG41066VF	YeeE YedE family protein
CLOST_1439	ENOG4108J2R	molybdopterin oxidoreductase
CLOST_1442	ENOG4105CIN	aminoacyl-histidine dipeptidase
CLOST_1444	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CLOST_1445	ENOG4107QI6	Cysteine desulfurase
CLOST_1447	ENOG4105HDK	L-asparaginase
CLOST_1448	ENOG4105CIZ	coA-substrate-specific enzyme activase
CLOST_1449	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
CLOST_1450	ENOG4105CBX	hi0933 family
CLOST_1452	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CLOST_1453	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CLOST_1454	ENOG4105DUM	transcriptional regulator, lysR family
CLOST_1455	ENOG4105DFM	M18 family aminopeptidase
CLOST_1456	ENOG4105CPI	Metal Dependent Phosphohydrolase
CLOST_1462	ENOG4105VCQ	rubredoxin
CLOST_1463	ENOG4105MCT	stage V sporulation protein S
CLOST_1464	ENOG4105BZU	Histidine kinase
CLOST_1465	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CLOST_1466	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CLOST_1468	ENOG4105CAT	Cytidine monophosphate kinase
CLOST_1472	ENOG4105DQU	oxidoreductase, subunit beta
CLOST_1473	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
CLOST_1475	ENOG4107QSA	Oxaloacetate decarboxylase
CLOST_1477	ENOG4105FE9	pseudouridine synthase
CLOST_1478	ENOG4108JCI	Transcriptional regulator
CLOST_1479	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CLOST_1480	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CLOST_1481	ENOG4108Z4T	Peptidase M50
CLOST_1482	ENOG4105CN5	Metallo-Beta-Lactamase
CLOST_1485	ENOG4105I3K	Ferric uptake regulator, Fur family
CLOST_1488	ENOG4105CPC	Aldo Keto reductase
CLOST_1490	ENOG4105VBH	UPF0297 protein
CLOST_1491	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CLOST_1493	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
CLOST_1496	ENOG4105D1H	recombination factor protein RarA
CLOST_1498	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CLOST_1499	ENOG4105C79	DNA protecting protein DprA
CLOST_1500	ENOG4105C0P	Mg chelatase subunit ChlI
CLOST_1504	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CLOST_1516	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
CLOST_1532	ENOG4108TFU	terminase (Small subunit)
CLOST_1541	ENOG4108UUM	single-stranded DNA-binding protein
CLOST_1549	ENOG4105PNS	DnaD domain protein
CLOST_1552	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CLOST_1559	ENOG4105XB7	anti-repressor protein
CLOST_1568	ENOG4108C33	Resolvase
CLOST_1569	ENOG4105C0P	Mg chelatase subunit ChlI
CLOST_1570	ENOG4105VFF	UPF0102 protein
CLOST_1571	ENOG4105D00	flagellar biosynthetic protein flhB
CLOST_1573	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CLOST_1574	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CLOST_1575	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CLOST_1576	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CLOST_1577	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CLOST_1578	ENOG4105VB6	UPF0109 protein
CLOST_1579	ENOG4105K5M	30s ribosomal protein S16
CLOST_1581	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
CLOST_1582	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CLOST_1585	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CLOST_1587	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CLOST_1588	ENOG4107R88	Chemotaxis protein (CheV)
CLOST_1589	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CLOST_1590	ENOG4105BZG	amino acid carrier protein
CLOST_1595	ENOG4105FF2	Type I DHQase
CLOST_1596	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CLOST_1598	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CLOST_1601	ENOG4105US7	Histidine kinase
CLOST_1602	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CLOST_1605	ENOG4105CDA	abc transporter atp-binding protein
CLOST_1606	ENOG4105E5Q	amino acid AbC transporter
CLOST_1607	ENOG4108HW3	(ABC) transporter
CLOST_1608	ENOG4105DBI	uridine monophosphokinase
CLOST_1611	ENOG4105DVE	abc transporter atp-binding protein
CLOST_1612	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
CLOST_1613	ENOG4105HKU	nucleoside recognition domain-containing protein
CLOST_1614	ENOG4105HKU	nucleoside recognition domain-containing protein
CLOST_1618	ENOG410631K	Membrane
CLOST_1619	ENOG4105CSR	polyphosphate kinase 2
CLOST_1620	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CLOST_1623	ENOG4107YTP	response regulator receiver protein
CLOST_1626	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
CLOST_1633	ENOG4105CJ1	ABC, transporter
CLOST_1635	ENOG4108DQE	riboflavin reductase
CLOST_1643	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CLOST_1645	ENOG4105C8J	)-transporter
CLOST_1647	ENOG4105CA9	Pyruvate kinase
CLOST_1648	ENOG4105CTQ	phosphohexokinase
CLOST_1649	ENOG4105C0B	DNA polymerase III (alpha subunit)
CLOST_1650	ENOG4105D01	(LipO)protein
CLOST_1651	ENOG4108UMI	ABC transporter, permease
CLOST_1652	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CLOST_1653	ENOG4105KRI	phosphocarrier protein (HPr
CLOST_1654	ENOG4105CIE	May be required for sporulation (By similarity)
CLOST_1655	ENOG41062IR	nudix hydrolase
CLOST_1656	ENOG4105CHW	UPF0052 protein
CLOST_1657	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CLOST_1659	ENOG4105D4A	Cell wall formation (By similarity)
CLOST_1662	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CLOST_1663	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
CLOST_1664	ENOG4105N5T	Radical SAM Protein
CLOST_1667	ENOG4105W4R	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
CLOST_1668	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
CLOST_1669	ENOG4105DSE	periplasmic solute binding protein
CLOST_1670	ENOG4108U5N	UPF0316 protein
CLOST_1678	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
CLOST_1679	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CLOST_1680	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CLOST_1681	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CLOST_1682	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CLOST_1683	ENOG4105CNU	cell division protein FtsK
CLOST_1684	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CLOST_1685	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CLOST_1686	ENOG4105DTN	riboflavin biosynthesis protein ribF
CLOST_1687	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CLOST_1689	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CLOST_1690	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CLOST_1691	ENOG4105VHM	ribosomal protein
CLOST_1693	ENOG4105CHV	Transcription elongation factor NusA
CLOST_1694	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CLOST_1695	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CLOST_1697	ENOG4105DZP	Membrane-associated zinc metalloprotease
CLOST_1698	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CLOST_1699	ENOG4105KNE	Phosphatidate cytidylyltransferase
CLOST_1700	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CLOST_1702	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CLOST_1703	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CLOST_1704	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CLOST_1705	ENOG4105CE9	30S ribosomal protein S2
CLOST_1709	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CLOST_1711	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
CLOST_1712	ENOG4107PHP	CheC --inhibitor of MCP methylation
CLOST_1713	ENOG4108V3W	Chemotaxis protein, CheW
CLOST_1714	ENOG4105CBS	Chea signal transduction histidine kinase
CLOST_1715	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CLOST_1718	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CLOST_1719	ENOG4105D7B	Flagellar biosynthesis protein flha
CLOST_1720	ENOG4105D00	flagellar biosynthetic protein flhB
CLOST_1721	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CLOST_1722	ENOG4105VS8	Flagellar biosynthetic protein fliq
CLOST_1723	ENOG4105CN7	Flagellar biosynthetic protein FliP
CLOST_1725	ENOG4107YTP	response regulator receiver protein
CLOST_1726	ENOG4105DD5	Flagellar motor switch protein
CLOST_1727	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CLOST_1729	ENOG4106VK6	Flagellar motor protein
CLOST_1731	ENOG4105E14	MotA TolQ exbB proton channel
CLOST_1733	ENOG4105BZE	flagellar hook protein, FlgE
CLOST_1734	ENOG410822I	Flagellar hook capping protein
CLOST_1735	ENOG4105WF4	Flagellar hook-length control protein
CLOST_1740	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CLOST_1741	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CLOST_1742	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CLOST_1743	ENOG4108ZC9	flagellar basal-body rod protein flgc
CLOST_1744	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CLOST_1745	ENOG4107RUE	extracellular solute-binding protein family 1
CLOST_1746	ENOG4105D38	putrescine abc transporter
CLOST_1747	ENOG4105F38	ABC transporter, permease
CLOST_1748	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CLOST_1750	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CLOST_1755	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CLOST_1756	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CLOST_1757	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
CLOST_1758	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLOST_1760	ENOG4105EEI	dihydropteroate synthase
CLOST_1761	ENOG4105EUJ	GTP cyclohydrolase i
CLOST_1763	ENOG4105CRQ	synthase (Component I)
CLOST_1764	ENOG4105DDQ	anthranilate synthase
CLOST_1765	ENOG41090I5	UPF0735 ACT domain-containing protein
CLOST_1766	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CLOST_1767	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CLOST_1768	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CLOST_1770	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CLOST_1771	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CLOST_1773	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
CLOST_1774	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CLOST_1775	ENOG4105KG3	cytidine deaminase
CLOST_1776	ENOG4107YR5	Diacylglycerol kinase
CLOST_1777	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CLOST_1778	ENOG4105C9A	Phoh family
CLOST_1779	ENOG4108YZ8	Superoxide reductase
CLOST_1783	ENOG4105DI5	UPF0365 protein
CLOST_1784	ENOG4105F7J	membrane-bound serine protease
CLOST_1786	ENOG4105KTH	gatB Yqey
CLOST_1787	ENOG4105VCC	30S ribosomal protein S21
CLOST_1788	ENOG4107YU2	histidine triad (hIT) protein
CLOST_1789	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CLOST_1790	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CLOST_1791	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CLOST_1792	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CLOST_1793	ENOG4105CFG	Acts as a chaperone (By similarity)
CLOST_1794	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLOST_1795	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CLOST_1797	ENOG4107QIV	Cytochrome c biogenesis protein
CLOST_1799	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CLOST_1801	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CLOST_1803	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CLOST_1804	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CLOST_1806	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
CLOST_1810	ENOG4108EC8	DNA internalization-related competence protein ComEC
CLOST_1813	ENOG4108JQ1	Dehydrogenase
CLOST_1814	ENOG4105CEV	competence damage-inducible protein
CLOST_1816	ENOG41090A4	Pterin carbinolamine dehydratase
CLOST_1821	ENOG41067XF	inhibitor
CLOST_1823	ENOG4105CSV	Glutaminase
CLOST_1824	ENOG4105FE9	pseudouridine synthase
CLOST_1825	ENOG4105E0A	ABC, transporter
CLOST_1826	ENOG4105EHG	Permease protein
CLOST_1827	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CLOST_1828	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CLOST_1829	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CLOST_1830	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CLOST_1831	ENOG4108UIN	ybak prolyl-trna synthetase associated region
CLOST_1832	ENOG4105BZU	Histidine kinase
CLOST_1835	ENOG4105CUZ	uba thif-type nad fad binding protein
CLOST_1837	ENOG4105CDE	UPF0348 protein
CLOST_1839	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CLOST_1840	ENOG4106H78	methyltransferase
CLOST_1841	ENOG4105CB5	ATP-dependent DNA helicase recG
CLOST_1843	ENOG4105DP4	dak2 domain fusion protein ylov
CLOST_1844	ENOG4108ZAA	Alkaline-shock protein
CLOST_1845	ENOG4105VB9	50S ribosomal protein l28
CLOST_1847	ENOG4105DJV	ribulose-phosphate 3-epimerase
CLOST_1848	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CLOST_1849	ENOG4105D9P	serine threonine protein kinase
CLOST_1850	ENOG4108ZF3	Phosphatase
CLOST_1851	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CLOST_1852	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CLOST_1855	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CLOST_1857	ENOG4105C25	Primosomal protein n'
CLOST_1858	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CLOST_1859	ENOG41084KE	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CLOST_1860	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CLOST_1861	ENOG4105KC4	UPF0296 protein
CLOST_1862	ENOG4105DSJ	YicC domain protein
CLOST_1863	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CLOST_1864	ENOG4105F23	Fibronectin-binding protein
CLOST_1865	ENOG4107U9T	Pfam:Ribonuclease_BN
CLOST_1866	ENOG4105HMI	Membrane
CLOST_1867	ENOG4105DUM	transcriptional regulator, lysR family
CLOST_1868	ENOG4105C2W	permease
CLOST_1869	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CLOST_1870	ENOG4105C34	Pseudouridine synthase
CLOST_1871	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CLOST_1872	ENOG4105C31	Tryptophanyl-tRNA synthetase
CLOST_1873	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CLOST_1876	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CLOST_1878	ENOG4105DBK	s4 domain protein
CLOST_1879	ENOG4108VIA	integral membrane protein
CLOST_1880	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CLOST_1881	ENOG4105DFA	alanine racemase domain protein
CLOST_1883	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CLOST_1884	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CLOST_1885	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CLOST_1887	ENOG4105BZU	Histidine kinase
CLOST_1888	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CLOST_1889	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CLOST_1890	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CLOST_1891	ENOG4105K67	small basic protein
CLOST_1892	ENOG4108R2U	division initiation protein
CLOST_1894	ENOG4108UFP	Essential cell division protein (By similarity)
CLOST_1895	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CLOST_1896	ENOG4105CNI	cell division protein FtsW
CLOST_1897	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CLOST_1898	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CLOST_1899	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
CLOST_1900	ENOG4105CJN	penicillin-binding protein
CLOST_1902	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CLOST_1903	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CLOST_1906	ENOG4105C3G	gtp-binding protein
CLOST_1910	ENOG4105C4R	Atp-dependent dna helicase
CLOST_1912	ENOG4105CIN	aminoacyl-histidine dipeptidase
CLOST_1913	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CLOST_1915	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
CLOST_1919	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CLOST_1920	ENOG4108WBT	adenosyltransferase
CLOST_1921	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CLOST_1923	ENOG4105SX7	Transporter
CLOST_1928	ENOG4105WH1	Two component transcriptional regulator luxr family
CLOST_1929	ENOG4105BZU	Histidine kinase
CLOST_1930	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
CLOST_1932	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CLOST_1934	ENOG4105ETE	Transcriptional regulator (LacI family
CLOST_1936	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CLOST_1937	ENOG4105EMS	pseudouridine synthase
CLOST_1938	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CLOST_1939	ENOG4108RE9	Phosphodiesterase
CLOST_1942	ENOG4108JU6	CBS domain protein
CLOST_1944	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CLOST_1952	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CLOST_1953	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CLOST_1958	ENOG4105E5G	Alpha beta hydrolase fold
CLOST_1965	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CLOST_1966	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CLOST_1967	ENOG4105KVH	Transcriptional regulator
CLOST_1972	ENOG4105II7	pyrroline-5-carboxylate reductase
CLOST_1973	ENOG4105BZU	Histidine kinase
CLOST_1978	ENOG4105K6H	D-cysteine desulfhydrase
CLOST_1979	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CLOST_1981	ENOG4105C02	permease
CLOST_1982	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CLOST_1983	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
CLOST_1984	ENOG4105DD7	kinase (PfkB family
CLOST_1987	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CLOST_1988	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CLOST_1990	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
CLOST_1991	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CLOST_1992	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CLOST_1994	ENOG4105DDQ	anthranilate synthase
CLOST_1995	ENOG4105CRQ	synthase (Component I)
CLOST_1999	ENOG4105KPV	Transcriptional regulator
CLOST_2002	ENOG4108Z3G	3H domain protein
CLOST_2007	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CLOST_2008	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CLOST_2009	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
CLOST_2010	ENOG4105DWF	phosphomethylpyrimidine kinase
CLOST_2012	ENOG4105DER	m42 family
CLOST_2013	ENOG4105C9B	Cysteine desulfurase
CLOST_2017	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CLOST_2018	ENOG4108Z0R	Transferase
CLOST_2025	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CLOST_2026	ENOG4105CGK	Exodeoxyribonuclease III
CLOST_2027	ENOG410810Y	Sulfite reductase
CLOST_2028	ENOG4107SHJ	sulfite reductase subunit b
CLOST_2029	ENOG4105D5B	Sulfite reductase, subunit A
CLOST_2031	ENOG4105IJJ	transcriptional regulator, crp fnr family
CLOST_2035	ENOG41088SP	formiminoglutamate hydrolase
CLOST_2037	ENOG41073R8	VanW family
CLOST_2039	ENOG4105C28	cystathionine
CLOST_2043	ENOG4105C8T	Leucyl-tRNA synthetase
CLOST_2045	ENOG4108UT2	hemolysin iii
CLOST_2048	ENOG4105NBU	tryptophan transport protein
CLOST_2049	ENOG4105VPX	protein, conserved in bacteria
CLOST_2050	ENOG4105C59	p-type ATPase
CLOST_2051	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_2052	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
CLOST_2053	ENOG4105CHH	sulfate transporter
CLOST_2060	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_2061	ENOG4105CPI	Metal Dependent Phosphohydrolase
CLOST_2062	ENOG4105W87	Cbs domain
CLOST_2063	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CLOST_2065	ENOG4105BZU	Histidine kinase
CLOST_2069	ENOG4105WWK	YheO domain protein
CLOST_2070	ENOG4105TMB	Formate nitrite transporter
CLOST_2072	ENOG4105DF9	Lipoate-protein, ligase
CLOST_2073	ENOG4105DSF	transport protein
CLOST_2074	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CLOST_2078	ENOG4107QMU	Mate efflux family protein
CLOST_2079	ENOG4105UQX	Mate efflux family protein
CLOST_2083	ENOG4105DR5	peptidase
CLOST_2084	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CLOST_2085	ENOG4105CAK	Cell division ATP-binding protein ftsE
CLOST_2086	ENOG4105CAK	Cell division ATP-binding protein ftsE
CLOST_2087	ENOG4105DF9	Lipoate-protein, ligase
CLOST_2088	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CLOST_2089	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CLOST_2093	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
CLOST_2094	ENOG4108JJB	ABC transporter
CLOST_2095	ENOG4108JJB	ABC transporter
CLOST_2100	ENOG4105HEE	Binding Domain protein
CLOST_2104	ENOG4108SHJ	s-layer protein
CLOST_2105	ENOG4105DAN	ATP-dependent protease
CLOST_2109	ENOG4107T7U	Sulfatase
CLOST_2111	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
CLOST_2112	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CLOST_2115	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CLOST_2116	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CLOST_2117	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CLOST_2118	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CLOST_2125	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CLOST_2126	ENOG4105ESV	Glycosyl transferase, family 4
CLOST_2128	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CLOST_2129	ENOG4108YZG	isomerase
CLOST_2131	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CLOST_2132	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CLOST_2133	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CLOST_2134	ENOG4105CBJ	Metal-dependent enzyme
CLOST_2135	ENOG4107104	thymidine kinase
CLOST_2136	ENOG41082DI	50s ribosomal protein l31
CLOST_2137	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CLOST_2138	ENOG4105CBT	Fructose-1,6-bisphosphatase
CLOST_2139	ENOG4105CBT	Fructose-1,6-bisphosphatase
CLOST_2141	ENOG4105KRN	Transcriptional regulator, abrb family
CLOST_2144	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CLOST_2145	ENOG4105MA4	psp1 domain protein
CLOST_2146	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CLOST_2147	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CLOST_2148	ENOG4105CVG	Homoserine O-transsuccinylase
CLOST_2150	ENOG4105CMQ	Chloride channel
CLOST_2151	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
CLOST_2158	ENOG4105EWC	Purine nucleoside phosphorylase
CLOST_2161	ENOG4108UJD	30S ribosomal protein S9
CLOST_2162	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CLOST_2163	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CLOST_2164	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
CLOST_2166	ENOG4108JJB	ABC transporter
CLOST_2167	ENOG4108JJB	ABC transporter
CLOST_2169	ENOG4108ZT0	50S ribosomal protein l17
CLOST_2170	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CLOST_2171	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CLOST_2172	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CLOST_2173	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLOST_2174	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CLOST_2176	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CLOST_2177	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CLOST_2178	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CLOST_2179	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CLOST_2180	ENOG4105VPB	50S ribosomal protein L30
CLOST_2181	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CLOST_2182	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CLOST_2183	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CLOST_2184	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CLOST_2185	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CLOST_2186	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLOST_2187	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CLOST_2188	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CLOST_2189	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CLOST_2190	ENOG41082SA	50s ribosomal protein l29
CLOST_2191	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CLOST_2192	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CLOST_2193	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CLOST_2194	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CLOST_2195	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLOST_2196	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CLOST_2197	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CLOST_2198	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CLOST_2199	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CLOST_2200	ENOG4108IV0	ABC, transporter
CLOST_2201	ENOG4105C0Z	ABC transporter
CLOST_2202	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CLOST_2203	ENOG4105C32	Amino acid ABC transporter (Permease)
CLOST_2206	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CLOST_2207	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CLOST_2208	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CLOST_2209	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CLOST_2210	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CLOST_2211	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CLOST_2212	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CLOST_2213	ENOG4108VZM	50s ribosomal protein L10
CLOST_2214	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CLOST_2215	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CLOST_2216	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CLOST_2217	ENOG410683Z	Preprotein translocase SecE subunit
CLOST_2218	ENOG4105WDJ	50S ribosomal protein L33
CLOST_2219	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CLOST_2220	ENOG4105QIV	RNA polymerase
CLOST_2222	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CLOST_2223	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
CLOST_2226	ENOG4105C8Q	Methyl-accepting chemotaxis
CLOST_2228	ENOG4105CTU	Proline racemase
CLOST_2229	ENOG41088D5	d-proline reductase
CLOST_2230	ENOG41088D5	d-proline reductase
CLOST_2234	ENOG41088D5	d-proline reductase
CLOST_2238	ENOG4108ZQX	ybak prolyl-trna synthetase
CLOST_2239	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CLOST_2240	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CLOST_2241	ENOG4105C8N	cysteinyl-tRNA synthetase
CLOST_2242	ENOG4105D7W	serine acetyltransferase
CLOST_2243	ENOG4105C6T	cysteine synthase
CLOST_2245	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CLOST_2246	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CLOST_2247	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CLOST_2249	ENOG4108JQ7	(ABC) transporter
CLOST_2250	ENOG4105C3U	ABC transporter
CLOST_2251	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CLOST_2260	ENOG4105FQP	Beta-lactamase
CLOST_2261	ENOG4105GR3	Histidine kinase
CLOST_2264	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_2265	ENOG4105C1J	atp-dependent rna helicase
CLOST_2266	ENOG4105VEQ	Cold shock protein
CLOST_2267	ENOG4108JQ6	ABC transporter
CLOST_2268	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CLOST_2271	ENOG4108BSC	Methyltransferase
CLOST_2274	ENOG4105VYW	UPF0251 protein
CLOST_2275	ENOG41090R7	Ferric uptake
CLOST_2277	ENOG4107QM5	aconitate hydratase
CLOST_2285	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
CLOST_2288	ENOG4105C5H	ABC transporter
CLOST_2290	ENOG4105C5H	ABC transporter
CLOST_2291	ENOG4108DBC	nitroreductase
CLOST_2292	ENOG41084EF	Ferredoxin
CLOST_2293	ENOG4105D82	Glutamate dehydrogenase
CLOST_2295	ENOG4107QIZ	NADH dehydrogenase
CLOST_2296	ENOG4105GKE	subunit e
CLOST_2297	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
CLOST_2298	ENOG4105C5H	ABC transporter
CLOST_2299	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CLOST_2300	ENOG410801F	ribosomal-protein-alanine acetyltransferase
CLOST_2301	ENOG41072GX	Peptidase M22 Glycoprotease
CLOST_2302	ENOG4105K8N	protein family UPF0079, ATPase
CLOST_2306	ENOG4105I03	Flagellin
CLOST_2310	ENOG4105EPR	degv family
CLOST_2311	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CLOST_2312	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CLOST_2313	ENOG4105MS2	ribosomal subunit Interface protein
CLOST_2314	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CLOST_2315	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
CLOST_2316	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
CLOST_2320	ENOG4107WUB	V-type ATPase 116 kDa subunit
CLOST_2327	ENOG4105WH1	Two component transcriptional regulator luxr family
CLOST_2331	ENOG4105MQ3	flagellar protein FliS
CLOST_2332	ENOG4107RT6	flagellar hook-associated
CLOST_2334	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CLOST_2335	ENOG4105J5G	Transferase hexapeptide repeat containing protein
CLOST_2336	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CLOST_2337	ENOG4107QQG	Dehydrogenase
CLOST_2338	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CLOST_2341	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CLOST_2342	ENOG4108IAJ	Nad-dependent epimerase dehydratase
CLOST_2344	ENOG4106WTF	Glycosyl transferase, family 2
CLOST_2345	ENOG4105I03	Flagellin
CLOST_2346	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CLOST_2347	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
CLOST_2348	ENOG4105I03	Flagellin
CLOST_2349	ENOG4105E1Q	flagellar hook-associated protein
CLOST_2353	ENOG4105RU3	
CLOST_2355	ENOG4105C7H	Helicase, RecD TraA family
CLOST_2356	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CLOST_2361	ENOG4105CGA	flagellar basal-body rod protein FlgG
CLOST_2362	ENOG4105CGA	flagellar basal-body rod protein FlgG
CLOST_2363	ENOG4105DFF	Rod shape-determining protein mreb
CLOST_2364	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CLOST_2367	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
CLOST_2368	ENOG4105CJW	magnesium transporter
CLOST_2370	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
CLOST_2371	ENOG4105CEM	UPF0597 protein
CLOST_2372	ENOG4105WWK	YheO domain protein
CLOST_2373	ENOG4108P49	AntiSigma factor
CLOST_2374	ENOG4105JVQ	RNA Polymerase
CLOST_2375	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_2376	ENOG4105E2X	shikimate dehydrogenase
CLOST_2377	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CLOST_2378	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CLOST_2379	ENOG4105D49	3-dehydroquinate synthase
CLOST_2381	ENOG4105BZU	Histidine kinase
CLOST_2384	ENOG4105DFD	Na H antiporter
CLOST_2386	ENOG4105E8R	UPF0173 metal-dependent hydrolase
CLOST_2387	ENOG4105C02	permease
CLOST_2388	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
CLOST_2393	ENOG4105IJJ	transcriptional regulator, crp fnr family
CLOST_2395	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CLOST_2398	ENOG4105VKD	bioY protein
CLOST_2399	ENOG4105C6K	Malic enzyme
CLOST_2401	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CLOST_2404	ENOG4107TXC	Transcriptional regulator
CLOST_2409	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
CLOST_2410	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CLOST_2411	ENOG4105CNN	ABC, transporter
CLOST_2412	ENOG4105C2J	ABC transporter
CLOST_2414	ENOG4108RVA	ribokinase
CLOST_2418	ENOG4105BZU	Histidine kinase
CLOST_2420	ENOG4108Z29	Flavodoxin
CLOST_2424	ENOG4105C5S	asparaginyl-tRNA synthetase
CLOST_2425	ENOG4107RM6	sulfurtransferase
CLOST_2427	ENOG4105K4I	Scp-like extracellular
CLOST_2433	ENOG4107RCH	Diaminopropionate ammonia-lyase
CLOST_2434	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CLOST_2435	ENOG4105BZU	Histidine kinase
CLOST_2436	ENOG4107SDU	Methyl-accepting chemotaxis
CLOST_2437	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
CLOST_2438	ENOG4105EAB	amino acid AbC transporter
CLOST_2439	ENOG4105E5Q	amino acid AbC transporter
CLOST_2440	ENOG4105CDA	abc transporter atp-binding protein
CLOST_2455	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CLOST_2458	ENOG4105E0X	reductase
CLOST_2460	ENOG4108ZJ4	polysaccharide deacetylase
CLOST_2462	ENOG4105EHG	Permease protein
CLOST_2463	ENOG4105DQ5	transport system permease protein
CLOST_2465	ENOG4105E0A	ABC, transporter
CLOST_2468	ENOG4108NGH	radical SAM domain protein
CLOST_2470	ENOG4105D9U	N-acetyltransferase
CLOST_2473	ENOG4105EFZ	amidohydrolase
CLOST_2475	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CLOST_2484	ENOG41075SV	phosphoribosyltransferase
CLOST_2485	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
CLOST_2487	ENOG4107R3N	Filamentation induced by cAMP protein fic
CLOST_2489	ENOG4105CJ1	ABC, transporter
CLOST_2493	ENOG41067QW	Transcriptional regulator
CLOST_2495	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CLOST_2497	ENOG4107Y80	Major Facilitator superfamily
CLOST_2498	ENOG4105YA8	Transcriptional regulator
CLOST_2502	ENOG4105D03	DNA-3-methyladenine glycosylase II
CLOST_2507	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CLOST_2528	ENOG4105W5Q	DNA repair protein (RadC
CLOST_2533	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CLOST_2538	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
CLOST_2539	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CLOST_2546	ENOG4105FA0	parb-like partition protein
CLOST_2547	ENOG4107QJE	Chromosome Partitioning Protein
CLOST_2548	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CLOST_2549	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CLOST_2550	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CLOST_2551	ENOG4105C0H	protease
CLOST_2552	ENOG4105Q2H	domain protein
CLOST_2556	ENOG4105BZU	Histidine kinase
CLOST_2557	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CLOST_2560	ENOG4108QTI	)-transporter
CLOST_2561	ENOG4105BZU	Histidine kinase
CLOST_2562	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CLOST_2564	ENOG4105CDU	Replicative dna helicase
CLOST_2565	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CLOST_2566	ENOG4105BZR	domain protein
CLOST_2569	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CLOST_2570	ENOG4108UUM	single-stranded DNA-binding protein
CLOST_2571	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CLOST_2572	ENOG4105VDK	protein, conserved in bacteria
CLOST_2578	ENOG4105C9B	Cysteine desulfurase
CLOST_2579	ENOG4105FA0	parb-like partition protein
CLOST_2580	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CLOST_2581	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CLOST_2582	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
CLOST_2583	ENOG4105CZV	ABC transporter
CLOST_2585	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CLOST_2587	ENOG4107R4E	Membrane
CLOST_2588	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CLOST_2589	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CLOST_2590	ENOG4105VG0	50S ribosomal protein l34