CLOST_0644 a31af0d903338632f2d826973cbaa2e6 248 SUPERFAMILY SSF51351 1 247 9.82E-97 T 13-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0644 a31af0d903338632f2d826973cbaa2e6 248 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 62.604 T 13-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0644 a31af0d903338632f2d826973cbaa2e6 248 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 13-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0644 a31af0d903338632f2d826973cbaa2e6 248 Pfam PF00121 Triosephosphate isomerase 5 246 1.8E-98 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0644 a31af0d903338632f2d826973cbaa2e6 248 Gene3D G3DSA:3.20.20.70 1 248 8.7E-106 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0644 a31af0d903338632f2d826973cbaa2e6 248 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 239 3.7E-63 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_1456 185865be9246c2d610982edc09d948ae 317 Pfam PF01966 HD domain 78 200 5.5E-12 T 13-10-2018 IPR006674 HD domain CLOST_1456 185865be9246c2d610982edc09d948ae 317 SUPERFAMILY SSF109604 59 238 6.77E-22 T 13-10-2018 CLOST_1456 185865be9246c2d610982edc09d948ae 317 Gene3D G3DSA:1.10.3210.10 3 240 1.2E-41 T 13-10-2018 CLOST_1456 185865be9246c2d610982edc09d948ae 317 SMART SM00471 73 209 9.1E-8 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 64 75 6.7E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 108 124 6.7E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.7E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 202 6.7E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 153 6.7E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 171 6.7E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 153 3.0E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 64 75 3.0E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 114 122 3.0E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 Gene3D G3DSA:3.40.50.720 1 229 1.3E-62 T 13-10-2018 CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 219 1.0E-48 T 13-10-2018 CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 SUPERFAMILY SSF51735 4 222 1.5E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0748 886798fdce4c17459c08892c75fcd46f 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 121 149 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 Gene3D G3DSA:1.20.1270.20 1 135 4.1E-40 T 13-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 Gene3D G3DSA:3.40.50.2030 370 542 6.7E-65 T 13-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 Pfam PF03063 Prismane/CO dehydrogenase family 1 539 2.8E-175 T 13-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 Gene3D G3DSA:1.20.1270.20 136 218 4.4E-29 T 13-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 PIRSF PIRSF000076 1 543 2.3E-255 T 13-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 SUPERFAMILY SSF56821 1 541 2.29E-205 T 13-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 Gene3D G3DSA:3.40.50.2030 219 367 6.0E-65 T 13-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 541 1.4E-223 T 13-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_0231 08d384b8c7974066c1f6436e0024b203 543 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 543 23.321 T 13-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_2091 19c52ce6944607d33257c5d548a4afc5 191 Gene3D G3DSA:3.30.200.20 1 63 7.8E-6 T 13-10-2018 CLOST_2091 19c52ce6944607d33257c5d548a4afc5 191 Pfam PF01163 RIO1 family 22 124 3.4E-6 T 13-10-2018 CLOST_2091 19c52ce6944607d33257c5d548a4afc5 191 SUPERFAMILY SSF56112 4 162 1.6E-19 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily CLOST_2483 b15d0df25c041282ef8f47bad3f8977f 269 Gene3D G3DSA:3.40.50.2020 9 128 5.8E-11 T 13-10-2018 CLOST_2483 b15d0df25c041282ef8f47bad3f8977f 269 Gene3D G3DSA:3.40.50.2020 134 266 1.2E-20 T 13-10-2018 CLOST_2483 b15d0df25c041282ef8f47bad3f8977f 269 SUPERFAMILY SSF53271 61 132 1.34E-6 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_2483 b15d0df25c041282ef8f47bad3f8977f 269 Pfam PF14572 Phosphoribosyl synthetase-associated domain 189 267 1.1E-7 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CLOST_2483 b15d0df25c041282ef8f47bad3f8977f 269 SUPERFAMILY SSF53271 137 264 3.8E-12 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_1305 1faa874962517b95175072ac1808ad50 729 Pfam PF04607 Region found in RelA / SpoT proteins 233 343 4.4E-39 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 CLOST_1305 1faa874962517b95175072ac1808ad50 729 SMART SM00471 39 151 1.1E-9 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_1305 1faa874962517b95175072ac1808ad50 729 Gene3D G3DSA:1.10.3210.10 1 189 6.2E-84 T 13-10-2018 CLOST_1305 1faa874962517b95175072ac1808ad50 729 Pfam PF02824 TGS domain 387 446 1.2E-20 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CLOST_1305 1faa874962517b95175072ac1808ad50 729 Gene3D G3DSA:3.10.20.30 380 452 1.7E-32 T 13-10-2018 IPR012675 Beta-grasp domain superfamily CLOST_1305 1faa874962517b95175072ac1808ad50 729 Pfam PF13328 HD domain 24 173 3.5E-49 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_1305 1faa874962517b95175072ac1808ad50 729 SUPERFAMILY SSF109604 2 188 1.66E-74 T 13-10-2018 CLOST_1305 1faa874962517b95175072ac1808ad50 729 SMART SM00954 233 343 5.4E-68 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 CLOST_1305 1faa874962517b95175072ac1808ad50 729 SUPERFAMILY SSF81271 374 446 1.05E-22 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CLOST_1305 1faa874962517b95175072ac1808ad50 729 Gene3D G3DSA:3.30.460.10 191 323 1.8E-53 T 13-10-2018 CLOST_1305 1faa874962517b95175072ac1808ad50 729 SUPERFAMILY SSF81301 178 391 4.25E-66 T 13-10-2018 CLOST_1305 1faa874962517b95175072ac1808ad50 729 Gene3D G3DSA:3.30.70.260 650 729 3.2E-17 T 13-10-2018 CLOST_1305 1faa874962517b95175072ac1808ad50 729 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 24 724 1.1E-257 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 CLOST_1305 1faa874962517b95175072ac1808ad50 729 Pfam PF13291 ACT domain 649 726 8.2E-20 T 13-10-2018 IPR002912 ACT domain CLOST_1305 1faa874962517b95175072ac1808ad50 729 SUPERFAMILY SSF55021 653 727 1.62E-10 T 13-10-2018 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 13-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 SUPERFAMILY SSF51621 2 343 8.03E-103 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 Gene3D G3DSA:2.40.33.10 72 168 6.4E-198 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 Pfam PF00224 Pyruvate kinase, barrel domain 4 343 4.6E-154 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 Gene3D G3DSA:3.50.30.10 475 583 2.3E-30 T 13-10-2018 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 471 4.7E-35 T 13-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 Pfam PF00391 PEP-utilising enzyme, mobile domain 502 573 1.1E-21 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.1E-80 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.1E-80 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.1E-80 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 PRINTS PR01050 Pyruvate kinase family signature 186 200 1.1E-80 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.1E-80 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.1E-80 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 PRINTS PR01050 Pyruvate kinase family signature 61 77 1.1E-80 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 SUPERFAMILY SSF52935 323 472 1.26E-41 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 Gene3D G3DSA:3.40.1380.20 336 468 6.4E-198 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 4 471 2.1E-191 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 SUPERFAMILY SSF50800 72 167 1.92E-28 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 Gene3D G3DSA:3.20.20.60 4 335 6.4E-198 T 13-10-2018 CLOST_1647 428d1d94f508cf56214c9b870a57f0f7 583 SUPERFAMILY SSF52009 466 581 5.49E-27 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 SMART SM00382 158 339 8.5E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 24 89 4.8E-9 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 Gene3D G3DSA:3.40.50.12240 13 436 9.2E-157 T 13-10-2018 CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 346 355 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 22 434 1.6E-206 T 13-10-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 355 4.9E-75 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 SUPERFAMILY SSF52540 93 361 8.77E-99 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 TIGRFAM TIGR02546 III_secr_ATP: type III secretion apparatus H+-transporting two-sector ATPase 18 434 5.4E-183 T 13-10-2018 IPR013380 ATPase, type III secretion system, H+-transporting GO:0005524|GO:0005737|GO:0006754|GO:0030254|GO:0030257|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_1738 36218f82b7f97cd0c854a75cd16fb85e 436 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 5 435 7.1E-192 T 13-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 Gene3D G3DSA:3.40.50.2300 64 326 2.7E-88 T 13-10-2018 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 Gene3D G3DSA:3.40.50.2300 165 331 2.7E-88 T 13-10-2018 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 50 1.3E-16 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 Pfam PF13377 Periplasmic binding protein-like domain 173 334 3.4E-35 T 13-10-2018 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.2E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.2E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 SUPERFAMILY SSF53822 63 334 1.85E-89 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 Gene3D G3DSA:1.10.260.40 1 61 1.0E-22 T 13-10-2018 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 SUPERFAMILY SSF47413 2 61 9.6E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 SMART SM00354 2 73 8.6E-31 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_2415 08ead59fa0d423911c892d9522c76a32 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 13-10-2018 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 SUPERFAMILY SSF46894 138 209 8.5E-23 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 SMART SM00448 1 111 2.0E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 203 2.5E-21 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 Gene3D G3DSA:3.40.50.12740 1 209 3.2E-70 T 13-10-2018 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.9E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.9E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.9E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 Pfam PF00072 Response regulator receiver domain 1 112 5.5E-32 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 SMART SM00421 146 203 6.3E-27 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_1928 1d7a678522ab6e560bf3dd1eda65459b 211 SUPERFAMILY SSF52172 1 127 5.69E-37 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 SUPERFAMILY SSF54211 449 564 7.08E-42 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Gene3D G3DSA:3.30.70.870 379 448 1.3E-18 T 13-10-2018 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 SMART SM00838 565 653 4.5E-40 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 SUPERFAMILY SSF50447 247 363 1.74E-26 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Gene3D G3DSA:3.30.230.10 451 653 1.6E-86 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Gene3D G3DSA:3.30.70.240 569 640 1.6E-86 T 13-10-2018 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Gene3D G3DSA:2.40.30.10 268 378 8.4E-29 T 13-10-2018 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 PRINTS PR00315 GTP-binding elongation factor signature 11 24 4.2E-6 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 PRINTS PR00315 GTP-binding elongation factor signature 117 126 4.2E-6 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 PRINTS PR00315 GTP-binding elongation factor signature 81 92 4.2E-6 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 PRINTS PR00315 GTP-binding elongation factor signature 65 75 4.2E-6 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Pfam PF03764 Elongation factor G, domain IV 447 563 2.9E-42 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 SUPERFAMILY SSF54980 568 657 6.71E-26 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Pfam PF03144 Elongation factor Tu domain 2 291 357 3.9E-7 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 SUPERFAMILY SSF52540 5 264 4.18E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Gene3D G3DSA:3.40.50.300 2 267 2.8E-66 T 13-10-2018 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Pfam PF00009 Elongation factor Tu GTP binding domain 8 264 1.6E-30 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Pfam PF14492 Elongation Factor G, domain II 371 443 3.6E-25 T 13-10-2018 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 SMART SM00889 447 563 2.6E-66 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 Pfam PF00679 Elongation factor G C-terminus 565 652 2.1E-28 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like CLOST_0431 cc55b440c215a637a5fda75ce1a3a099 662 SUPERFAMILY SSF54980 371 448 2.23E-19 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_1665 bee90bb114170d771e223d17dc718de3 576 Gene3D G3DSA:3.40.120.10 211 325 6.8E-24 T 13-10-2018 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 SUPERFAMILY SSF55957 444 572 4.84E-15 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 510 557 5.9E-8 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 SUPERFAMILY SSF53738 210 318 2.83E-21 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 Gene3D G3DSA:3.30.310.50 489 568 7.4E-11 T 13-10-2018 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 451 7.1E-21 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 Gene3D G3DSA:3.40.120.10 326 452 6.8E-37 T 13-10-2018 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 SUPERFAMILY SSF53738 305 454 6.28E-29 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 142 151 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 212 312 3.7E-22 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 SUPERFAMILY SSF53738 32 237 4.32E-46 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 Gene3D G3DSA:3.40.120.10 36 187 1.0E-45 T 13-10-2018 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 45 183 7.0E-40 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 297 312 9.0E-8 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 230 249 9.0E-8 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1665 bee90bb114170d771e223d17dc718de3 576 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 141 155 9.0E-8 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_2346 f52cc2bfd28f10aa31cb1e7d3fbcbdc9 77 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 72 17.34 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 CLOST_2346 f52cc2bfd28f10aa31cb1e7d3fbcbdc9 77 Gene3D G3DSA:3.30.70.1680 1 62 1.2E-22 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 CLOST_2346 f52cc2bfd28f10aa31cb1e7d3fbcbdc9 77 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 64 3.9E-21 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 CLOST_2346 f52cc2bfd28f10aa31cb1e7d3fbcbdc9 77 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 49 2.0E-11 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 CLOST_2346 f52cc2bfd28f10aa31cb1e7d3fbcbdc9 77 SUPERFAMILY SSF117130 1 54 3.27E-17 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 CLOST_2346 f52cc2bfd28f10aa31cb1e7d3fbcbdc9 77 Pfam PF02599 Global regulator protein family 1 52 6.7E-22 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 SMART SM00283 316 591 2.1E-57 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 Gene3D G3DSA:1.10.287.950 291 591 1.0E-58 T 13-10-2018 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 396 544 7.5E-37 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 Gene3D G3DSA:1.20.1480.50 194 290 2.8E-7 T 13-10-2018 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 Pfam PF17200 Single Cache domain 2 48 194 4.8E-33 T 13-10-2018 IPR033480 Single Cache domain 2 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 SMART SM01049 43 137 6.0E-20 T 13-10-2018 IPR033480 Single Cache domain 2 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 Gene3D G3DSA:3.30.450.20 42 193 1.9E-34 T 13-10-2018 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 SUPERFAMILY SSF58104 262 590 1.31E-64 T 13-10-2018 CLOST_2151 302efc6af349c128d959a5763f2565f5 592 SMART SM00304 231 287 0.002 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 Gene3D G3DSA:3.40.50.300 2 280 4.6E-58 T 13-10-2018 CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 Pfam PF00005 ABC transporter 335 467 7.7E-14 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 Pfam PF12848 ABC transporter 224 303 4.4E-21 T 13-10-2018 IPR032781 ABC-transporter extension domain CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 SUPERFAMILY SSF52540 6 237 1.73E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 Pfam PF00005 ABC transporter 18 184 6.5E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 SUPERFAMILY SSF52540 294 517 5.97E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 SMART SM00382 344 513 0.58 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 SMART SM00382 26 228 2.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0133 b77f21916cf52f1bc5ef6b9cbc7dcc55 527 Gene3D G3DSA:3.40.50.300 282 527 1.1E-44 T 13-10-2018 CLOST_0033 822bc2afceb03a180f411886da344f20 955 Gene3D G3DSA:1.25.40.10 97 246 9.0E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0033 822bc2afceb03a180f411886da344f20 955 SUPERFAMILY SSF48452 161 232 4.17E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0033 822bc2afceb03a180f411886da344f20 955 SUPERFAMILY SSF48452 695 886 1.02E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0033 822bc2afceb03a180f411886da344f20 955 SMART SM00028 859 892 240.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_0033 822bc2afceb03a180f411886da344f20 955 SMART SM00028 819 852 3.3E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_0033 822bc2afceb03a180f411886da344f20 955 Gene3D G3DSA:3.40.50.300 247 433 2.1E-8 T 13-10-2018 CLOST_0033 822bc2afceb03a180f411886da344f20 955 SUPERFAMILY SSF52540 246 492 3.56E-11 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0033 822bc2afceb03a180f411886da344f20 955 Gene3D G3DSA:1.25.40.10 695 953 1.8E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0033 822bc2afceb03a180f411886da344f20 955 Gene3D G3DSA:1.10.10.10 2 93 4.6E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0033 822bc2afceb03a180f411886da344f20 955 Pfam PF03704 Bacterial transcriptional activator domain 109 229 4.0E-12 T 13-10-2018 IPR005158 Bacterial transcriptional activator domain CLOST_0033 822bc2afceb03a180f411886da344f20 955 Pfam PF13191 AAA ATPase domain 248 399 1.2E-13 T 13-10-2018 CLOST_0033 822bc2afceb03a180f411886da344f20 955 SMART SM01043 90 229 0.0013 T 13-10-2018 IPR005158 Bacterial transcriptional activator domain CLOST_0134 450164e9c29eceb9875bbd85d4d2af44 411 SMART SM00487 22 219 9.7E-61 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_0134 450164e9c29eceb9875bbd85d4d2af44 411 Gene3D G3DSA:3.40.50.300 3 208 1.8E-74 T 13-10-2018 CLOST_0134 450164e9c29eceb9875bbd85d4d2af44 411 Pfam PF00270 DEAD/DEAH box helicase 27 193 7.4E-51 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOST_0134 450164e9c29eceb9875bbd85d4d2af44 411 Gene3D G3DSA:3.40.50.300 212 410 1.2E-52 T 13-10-2018 CLOST_0134 450164e9c29eceb9875bbd85d4d2af44 411 SMART SM00490 255 336 3.2E-32 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0134 450164e9c29eceb9875bbd85d4d2af44 411 Pfam PF00271 Helicase conserved C-terminal domain 228 336 8.8E-30 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0134 450164e9c29eceb9875bbd85d4d2af44 411 SUPERFAMILY SSF52540 71 349 1.68E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1657 0dc903850e563395732c40ee380d7eb1 285 Pfam PF03668 P-loop ATPase protein family 1 282 8.1E-106 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 CLOST_1657 0dc903850e563395732c40ee380d7eb1 285 Gene3D G3DSA:3.40.50.300 53 164 2.6E-8 T 13-10-2018 CLOST_1657 0dc903850e563395732c40ee380d7eb1 285 PIRSF PIRSF005052 1 285 6.8E-108 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 CLOST_1657 0dc903850e563395732c40ee380d7eb1 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 284 40.333 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 CLOST_1657 0dc903850e563395732c40ee380d7eb1 285 SUPERFAMILY SSF52540 1 156 1.65E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0521 0903493a250d10a63210428713bbd97c 424 PRINTS PR00083 Histidinol dehydrogenase signature 227 248 5.3E-82 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 PRINTS PR00083 Histidinol dehydrogenase signature 358 376 5.3E-82 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 5.3E-82 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 PRINTS PR00083 Histidinol dehydrogenase signature 318 343 5.3E-82 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 PRINTS PR00083 Histidinol dehydrogenase signature 168 194 5.3E-82 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 PRINTS PR00083 Histidinol dehydrogenase signature 198 223 5.3E-82 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 PRINTS PR00083 Histidinol dehydrogenase signature 249 268 5.3E-82 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 PRINTS PR00083 Histidinol dehydrogenase signature 133 159 5.3E-82 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 Gene3D G3DSA:3.40.50.1980 31 229 3.3E-119 T 13-10-2018 CLOST_0521 0903493a250d10a63210428713bbd97c 424 PIRSF PIRSF000099 1 424 1.2E-155 T 13-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 423 1.6E-156 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 Pfam PF00815 Histidinol dehydrogenase 21 423 3.7E-163 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 SUPERFAMILY SSF53720 22 420 3.92E-75 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 CLOST_0521 0903493a250d10a63210428713bbd97c 424 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 227 259 - T 13-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_0521 0903493a250d10a63210428713bbd97c 424 Gene3D G3DSA:3.40.50.1980 231 346 3.3E-119 T 13-10-2018 CLOST_0521 0903493a250d10a63210428713bbd97c 424 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 424 39.543 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CLOST_1364 5e708b62412295cc4a4ca88b582cec36 290 Pfam PF03313 Serine dehydratase alpha chain 15 276 1.2E-75 T 13-10-2018 IPR005130 Serine dehydratase-like, alpha subunit CLOST_1364 5e708b62412295cc4a4ca88b582cec36 290 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 3 289 4.9E-107 T 13-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CLOST_0533 1576ec449f14e4384f20d287f027ff3f 101 Pfam PF03551 Transcriptional regulator PadR-like family 18 87 9.2E-22 T 13-10-2018 IPR005149 Transcription regulator PadR, N-terminal CLOST_0533 1576ec449f14e4384f20d287f027ff3f 101 Gene3D G3DSA:1.10.10.10 1 101 8.8E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0533 1576ec449f14e4384f20d287f027ff3f 101 SUPERFAMILY SSF46785 4 99 3.44E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 SUPERFAMILY SSF56024 110 317 7.06E-53 T 13-10-2018 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 SUPERFAMILY SSF56024 276 471 1.59E-49 T 13-10-2018 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 Pfam PF13396 Phospholipase_D-nuclease N-terminal 9 50 4.1E-11 T 13-10-2018 IPR027379 Cardiolipin synthase N-terminal CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 Gene3D G3DSA:3.30.870.10 120 314 3.3E-43 T 13-10-2018 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 Pfam PF13091 PLD-like domain 330 454 1.3E-26 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 Pfam PF13091 PLD-like domain 141 259 1.0E-12 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 Gene3D G3DSA:3.30.870.10 316 463 4.2E-28 T 13-10-2018 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 2 487 2.5E-160 T 13-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 SMART SM00155 400 427 9.7E-5 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 SMART SM00155 224 251 8.3E-6 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CLOST_0284 1b121cad32673aa764faaea22e0b5262 487 Hamap MF_01916 Cardiolipin synthase. 3 487 43.345 T 13-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 Gene3D G3DSA:3.40.50.1220 187 348 6.8E-46 T 13-10-2018 CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 Gene3D G3DSA:3.40.50.970 349 547 1.2E-53 T 13-10-2018 CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 SUPERFAMILY SSF52518 3 174 1.47E-59 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 510 6.2E-38 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 173 1.9E-55 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 545 1.1E-187 T 13-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 412 431 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 SUPERFAMILY SSF52467 190 336 2.58E-45 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 SUPERFAMILY SSF52518 352 544 1.9E-54 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 Gene3D G3DSA:3.40.50.970 1 186 6.9E-68 T 13-10-2018 CLOST_1423 1966794c5cf22a6830075f3e86533ef3 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 2.3E-38 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CLOST_2485 b89d5497dba6092719043f7881c94ff9 247 SUPERFAMILY SSF52402 3 242 2.65E-58 T 13-10-2018 CLOST_2485 b89d5497dba6092719043f7881c94ff9 247 Pfam PF02540 NAD synthase 13 232 1.1E-55 T 13-10-2018 IPR022310 NAD/GMP synthase CLOST_2485 b89d5497dba6092719043f7881c94ff9 247 Gene3D G3DSA:3.40.50.620 1 245 2.3E-68 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_2485 b89d5497dba6092719043f7881c94ff9 247 TIGRFAM TIGR00552 nadE: NAD+ synthetase 8 241 1.6E-59 T 13-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CLOST_1746 5a2c4983af2aeef10308302423b9913f 244 Gene3D G3DSA:1.10.3720.10 1 240 5.1E-51 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1746 5a2c4983af2aeef10308302423b9913f 244 SUPERFAMILY SSF161098 1 230 2.22E-55 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1746 5a2c4983af2aeef10308302423b9913f 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 56 229 4.3E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 SUPERFAMILY SSF109998 250 427 2.55E-40 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 SUPERFAMILY SSF54534 89 244 1.75E-34 T 13-10-2018 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 SUPERFAMILY SSF102735 1 130 6.02E-33 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 Gene3D G3DSA:3.30.70.1050 2 114 9.7E-27 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 Gene3D G3DSA:3.10.50.40 151 248 2.5E-91 T 13-10-2018 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 3.5E-38 T 13-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 422 3.3E-38 T 13-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 TIGRFAM TIGR00115 tig: trigger factor 13 422 1.6E-132 T 13-10-2018 IPR005215 Trigger factor GO:0015031 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 PIRSF PIRSF003095 1 428 9.6E-123 T 13-10-2018 IPR005215 Trigger factor GO:0015031 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 Hamap MF_00303 Trigger factor [tig]. 1 428 22.076 T 13-10-2018 IPR005215 Trigger factor GO:0015031 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 Gene3D G3DSA:1.10.3120.10 115 426 2.5E-91 T 13-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 CLOST_0589 030f09dcef8eb62a6994b77bf520efc8 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 239 5.5E-14 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CLOST_2409 659c0b088ffa49064b53c3e6f1a231a9 275 Gene3D G3DSA:3.40.1190.20 1 274 9.2E-58 T 13-10-2018 IPR029056 Ribokinase-like CLOST_2409 659c0b088ffa49064b53c3e6f1a231a9 275 Pfam PF08543 Phosphomethylpyrimidine kinase 43 259 1.9E-19 T 13-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CLOST_2409 659c0b088ffa49064b53c3e6f1a231a9 275 SUPERFAMILY SSF53613 4 259 8.73E-46 T 13-10-2018 IPR029056 Ribokinase-like CLOST_1094 c8a94f457ebbb9d42e43761ad715fe85 259 SUPERFAMILY SSF51658 25 249 2.75E-14 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily CLOST_1094 c8a94f457ebbb9d42e43761ad715fe85 259 Gene3D G3DSA:3.20.20.150 7 258 6.4E-21 T 13-10-2018 CLOST_2404 eaa7f7d2b487200d3065055e779e8ada 242 Pfam PF07739 TipAS antibiotic-recognition domain 129 237 4.6E-30 T 13-10-2018 IPR012925 TipAS antibiotic-recognition domain CLOST_2404 eaa7f7d2b487200d3065055e779e8ada 242 Gene3D G3DSA:1.10.1660.10 1 138 4.8E-48 T 13-10-2018 CLOST_2404 eaa7f7d2b487200d3065055e779e8ada 242 SMART SM00422 2 70 3.7E-29 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_2404 eaa7f7d2b487200d3065055e779e8ada 242 SUPERFAMILY SSF89082 155 238 8.5E-26 T 13-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain CLOST_2404 eaa7f7d2b487200d3065055e779e8ada 242 SUPERFAMILY SSF46955 2 110 2.89E-27 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily CLOST_2404 eaa7f7d2b487200d3065055e779e8ada 242 Pfam PF13411 MerR HTH family regulatory protein 3 68 1.1E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_2404 eaa7f7d2b487200d3065055e779e8ada 242 Gene3D G3DSA:1.10.490.50 154 242 2.6E-20 T 13-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain CLOST_1185 d99587bae913b0f03fbe9d2c4b01e156 139 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 9 125 7.7E-21 T 13-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CLOST_0443 c0611826b3a87c59e94f9ecfaa517bbc 185 Gene3D G3DSA:2.160.10.10 4 185 1.7E-35 T 13-10-2018 CLOST_0443 c0611826b3a87c59e94f9ecfaa517bbc 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 162 3.2E-9 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_0443 c0611826b3a87c59e94f9ecfaa517bbc 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CLOST_0443 c0611826b3a87c59e94f9ecfaa517bbc 185 SUPERFAMILY SSF51161 33 183 3.33E-33 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 ProSitePatterns PS00550 Hemerythrin family signature. 731 754 - T 13-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SMART SM00267 485 662 2.8E-60 T 13-10-2018 IPR000160 GGDEF domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 Pfam PF00990 Diguanylate cyclase, GGDEF domain 498 658 1.9E-49 T 13-10-2018 IPR000160 GGDEF domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 231 348 1.6E-16 T 13-10-2018 IPR000014 PAS domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 351 476 3.5E-15 T 13-10-2018 IPR000014 PAS domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SUPERFAMILY SSF55073 502 660 2.12E-46 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SUPERFAMILY SSF47188 677 802 2.35E-19 T 13-10-2018 IPR035938 Hemerythrin-like superfamily CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 Gene3D G3DSA:3.30.70.270 482 661 5.7E-58 T 13-10-2018 CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 Pfam PF13426 PAS domain 241 342 8.4E-12 T 13-10-2018 IPR000014 PAS domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 Pfam PF13426 PAS domain 372 471 1.9E-7 T 13-10-2018 IPR000014 PAS domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 679 802 1.4E-22 T 13-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SUPERFAMILY SSF55785 340 470 3.66E-16 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SMART SM00086 303 343 0.27 T 13-10-2018 IPR001610 PAC motif CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SMART SM00086 430 472 0.007 T 13-10-2018 IPR001610 PAC motif CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SMART SM00091 230 296 7.6E-4 T 13-10-2018 IPR000014 PAS domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SMART SM00091 355 423 41.0 T 13-10-2018 IPR000014 PAS domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 Gene3D G3DSA:1.20.120.50 673 805 4.4E-21 T 13-10-2018 IPR035938 Hemerythrin-like superfamily CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 SUPERFAMILY SSF55785 221 341 6.11E-16 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 Gene3D G3DSA:3.30.450.20 366 477 2.5E-13 T 13-10-2018 CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 494 660 5.7E-54 T 13-10-2018 IPR000160 GGDEF domain CLOST_2281 53392c55704cfa88c0a535d270a6832f 805 Gene3D G3DSA:3.30.450.20 216 365 2.6E-23 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 SUPERFAMILY SSF54211 599 774 4.93E-57 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 680 688 - T 13-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Gene3D G3DSA:2.30.130.40 9 117 4.0E-30 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Gene3D G3DSA:1.10.8.60 495 588 2.4E-32 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 TIGRFAM TIGR00763 lon: endopeptidase La 13 775 6.3E-304 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 PIRSF PIRSF001174 1 779 0.0 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 SUPERFAMILY SSF88697 11 203 3.73E-40 T 13-10-2018 IPR015947 PUA-like superfamily CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Gene3D G3DSA:3.30.230.10 598 788 5.4E-83 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 574 776 2.5E-95 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Gene3D G3DSA:3.40.50.300 317 494 6.9E-69 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 12 203 5.4E-38 T 13-10-2018 IPR003111 Lon, substrate-binding domain CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 SUPERFAMILY SSF52540 314 590 1.03E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 355 492 4.9E-24 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 SMART SM00464 11 205 9.6E-59 T 13-10-2018 IPR003111 Lon, substrate-binding domain CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 SMART SM00382 351 496 4.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 677 696 1.2E-54 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 359 378 1.2E-54 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 707 726 1.2E-54 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 599 615 1.2E-54 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 730 748 1.2E-54 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Gene3D G3DSA:1.20.58.1480 124 248 3.1E-37 T 13-10-2018 CLOST_0593 13d2c470760d9f839b8991a2ae39d33e 791 Hamap MF_01973 Lon protease [lon]. 12 776 71.298 T 13-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CLOST_2334 3b05b9cb277fd06cb2be16e892a77ef5 377 Gene3D G3DSA:3.40.640.10 1 250 3.6E-77 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_2334 3b05b9cb277fd06cb2be16e892a77ef5 377 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 368 8.4E-95 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_2334 3b05b9cb277fd06cb2be16e892a77ef5 377 PIRSF PIRSF000390 2 377 2.8E-83 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_2334 3b05b9cb277fd06cb2be16e892a77ef5 377 SUPERFAMILY SSF53383 15 375 2.48E-94 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_2334 3b05b9cb277fd06cb2be16e892a77ef5 377 Gene3D G3DSA:3.90.1150.10 257 374 9.9E-30 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0609 03a717adba1c5509183521ddcd8af13a 674 SMART SM00304 317 369 4.0E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0609 03a717adba1c5509183521ddcd8af13a 674 SUPERFAMILY SSF58104 337 672 2.62E-66 T 13-10-2018 CLOST_0609 03a717adba1c5509183521ddcd8af13a 674 Gene3D G3DSA:1.10.287.950 367 673 1.1E-60 T 13-10-2018 CLOST_0609 03a717adba1c5509183521ddcd8af13a 674 SMART SM00283 398 673 3.5E-56 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0609 03a717adba1c5509183521ddcd8af13a 674 Gene3D G3DSA:3.30.450.20 194 293 9.5E-11 T 13-10-2018 CLOST_0609 03a717adba1c5509183521ddcd8af13a 674 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 463 626 2.1E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0609 03a717adba1c5509183521ddcd8af13a 674 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 426 455 9.2E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0609 03a717adba1c5509183521ddcd8af13a 674 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 525 554 9.2E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_1479 0d43b78289e06cf3fdc36c66ec95793c 196 SUPERFAMILY SSF46785 24 104 7.89E-9 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1479 0d43b78289e06cf3fdc36c66ec95793c 196 PIRSF PIRSF019345 12 196 3.2E-45 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CLOST_1479 0d43b78289e06cf3fdc36c66ec95793c 196 SUPERFAMILY SSF46785 109 183 2.99E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1479 0d43b78289e06cf3fdc36c66ec95793c 196 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 28 194 6.7E-39 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CLOST_1479 0d43b78289e06cf3fdc36c66ec95793c 196 Gene3D G3DSA:1.10.10.10 19 108 4.1E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1479 0d43b78289e06cf3fdc36c66ec95793c 196 Gene3D G3DSA:1.10.10.10 109 196 9.5E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1479 0d43b78289e06cf3fdc36c66ec95793c 196 Pfam PF04079 Segregation and condensation complex subunit ScpB 29 191 5.8E-49 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CLOST_0460 0b8bc763f191659c1a6178f3ac3b626e 291 SUPERFAMILY SSF53448 2 269 8.97E-70 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0460 0b8bc763f191659c1a6178f3ac3b626e 291 Pfam PF00483 Nucleotidyl transferase 6 266 7.8E-34 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CLOST_0460 0b8bc763f191659c1a6178f3ac3b626e 291 Gene3D G3DSA:3.90.550.10 1 291 1.6E-95 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0460 0b8bc763f191659c1a6178f3ac3b626e 291 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 2.1E-123 T 13-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CLOST_1312 7479693162cfb169ba248e4db20adf96 371 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 370 3.4E-177 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CLOST_1312 7479693162cfb169ba248e4db20adf96 371 Gene3D G3DSA:3.20.20.105 1 371 5.4E-174 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CLOST_1312 7479693162cfb169ba248e4db20adf96 371 SUPERFAMILY SSF51713 3 369 2.62E-164 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CLOST_1312 7479693162cfb169ba248e4db20adf96 371 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 370 3.4E-169 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CLOST_1312 7479693162cfb169ba248e4db20adf96 371 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 9.1E-95 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CLOST_1312 7479693162cfb169ba248e4db20adf96 371 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 58.094 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CLOST_0949 056c0549f3c02b31d5afe18c31485a5a 256 Gene3D G3DSA:3.30.420.40 89 256 3.5E-59 T 13-10-2018 CLOST_0949 056c0549f3c02b31d5afe18c31485a5a 256 SUPERFAMILY SSF53067 123 254 1.47E-36 T 13-10-2018 CLOST_0949 056c0549f3c02b31d5afe18c31485a5a 256 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 255 35.632 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CLOST_0949 056c0549f3c02b31d5afe18c31485a5a 256 Pfam PF03309 Type III pantothenate kinase 2 204 6.0E-70 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CLOST_0949 056c0549f3c02b31d5afe18c31485a5a 256 Gene3D G3DSA:3.30.420.40 1 88 8.0E-32 T 13-10-2018 CLOST_0949 056c0549f3c02b31d5afe18c31485a5a 256 SUPERFAMILY SSF53067 1 122 2.85E-36 T 13-10-2018 CLOST_0949 056c0549f3c02b31d5afe18c31485a5a 256 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 251 3.9E-78 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CLOST_0406 68df2ca43eafb172eb67d306602a5e7f 690 SMART SM00283 414 689 2.6E-53 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0406 68df2ca43eafb172eb67d306602a5e7f 690 SUPERFAMILY SSF103190 185 304 5.49E-13 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0406 68df2ca43eafb172eb67d306602a5e7f 690 Gene3D G3DSA:1.10.287.950 388 689 5.7E-59 T 13-10-2018 CLOST_0406 68df2ca43eafb172eb67d306602a5e7f 690 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 484 630 8.1E-34 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0406 68df2ca43eafb172eb67d306602a5e7f 690 Gene3D G3DSA:1.20.1480.50 292 387 1.6E-11 T 13-10-2018 CLOST_0406 68df2ca43eafb172eb67d306602a5e7f 690 SUPERFAMILY SSF58104 360 688 1.06E-62 T 13-10-2018 CLOST_0406 68df2ca43eafb172eb67d306602a5e7f 690 SMART SM00304 330 385 0.0057 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0406 68df2ca43eafb172eb67d306602a5e7f 690 Pfam PF17203 Single cache domain 3 200 307 6.8E-10 T 13-10-2018 IPR033463 Single cache domain 3 CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 Gene3D G3DSA:3.40.50.1100 63 159 1.3E-119 T 13-10-2018 CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 55 68 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 34 410 1.2E-138 T 13-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 SUPERFAMILY SSF55021 334 410 5.24E-7 T 13-10-2018 CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 Gene3D G3DSA:3.40.50.1100 22 319 1.3E-119 T 13-10-2018 CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 28 314 1.0E-80 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 SUPERFAMILY SSF53686 18 321 6.02E-97 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 Gene3D G3DSA:3.30.70.260 335 410 4.9E-5 T 13-10-2018 CLOST_0395 1cf42425198e24d174bdce5ad2c02d9c 413 Pfam PF01842 ACT domain 340 406 2.8E-7 T 13-10-2018 IPR002912 ACT domain CLOST_1495 d0b76eefffa224d3e43b2da0c86fc9e3 148 Pfam PF02082 Transcriptional regulator 2 84 6.5E-25 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type CLOST_1495 d0b76eefffa224d3e43b2da0c86fc9e3 148 SUPERFAMILY SSF46785 2 135 8.46E-34 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1495 d0b76eefffa224d3e43b2da0c86fc9e3 148 Gene3D G3DSA:1.10.10.10 1 146 2.5E-49 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1495 d0b76eefffa224d3e43b2da0c86fc9e3 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 133 7.5E-38 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type CLOST_1495 d0b76eefffa224d3e43b2da0c86fc9e3 148 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 50 68 - T 13-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CLOST_2239 243f799a04f145699681268824f65305 481 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 108 275 3.4E-17 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2239 243f799a04f145699681268824f65305 481 Pfam PF03129 Anticodon binding domain 294 387 7.2E-22 T 13-10-2018 IPR004154 Anticodon-binding CLOST_2239 243f799a04f145699681268824f65305 481 Gene3D G3DSA:3.30.930.10 8 287 2.3E-105 T 13-10-2018 CLOST_2239 243f799a04f145699681268824f65305 481 Hamap MF_01571 Proline--tRNA ligase [proS]. 12 481 45.586 T 13-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CLOST_2239 243f799a04f145699681268824f65305 481 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 414 481 4.8E-23 T 13-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CLOST_2239 243f799a04f145699681268824f65305 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 9.1E-11 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CLOST_2239 243f799a04f145699681268824f65305 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 150 161 9.1E-11 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CLOST_2239 243f799a04f145699681268824f65305 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 111 122 9.1E-11 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CLOST_2239 243f799a04f145699681268824f65305 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 141 149 9.1E-11 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CLOST_2239 243f799a04f145699681268824f65305 481 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 13 481 1.2E-186 T 13-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CLOST_2239 243f799a04f145699681268824f65305 481 SUPERFAMILY SSF52954 283 406 5.13E-36 T 13-10-2018 CLOST_2239 243f799a04f145699681268824f65305 481 SMART SM00946 414 481 1.8E-28 T 13-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CLOST_2239 243f799a04f145699681268824f65305 481 SUPERFAMILY SSF55681 17 280 1.18E-79 T 13-10-2018 CLOST_2239 243f799a04f145699681268824f65305 481 SUPERFAMILY SSF64586 409 481 1.28E-22 T 13-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CLOST_2239 243f799a04f145699681268824f65305 481 Gene3D G3DSA:3.30.110.30 408 481 1.0E-22 T 13-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CLOST_2239 243f799a04f145699681268824f65305 481 Gene3D G3DSA:3.40.50.800 288 405 1.1E-37 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily CLOST_2354 a3f9e457359f63c6f5bf3be7cb53dc89 190 SUPERFAMILY SSF53271 15 185 8.07E-19 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_2354 a3f9e457359f63c6f5bf3be7cb53dc89 190 Pfam PF00156 Phosphoribosyl transferase domain 129 186 1.0E-7 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOST_2354 a3f9e457359f63c6f5bf3be7cb53dc89 190 Gene3D G3DSA:3.40.50.2020 58 190 5.6E-15 T 13-10-2018 CLOST_2533 37d8b5c673e580c89b7be04d53390c11 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 31.191 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 CLOST_2533 37d8b5c673e580c89b7be04d53390c11 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 3.4E-62 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 CLOST_2533 37d8b5c673e580c89b7be04d53390c11 159 SUPERFAMILY SSF75217 1 157 1.26E-60 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases CLOST_2533 37d8b5c673e580c89b7be04d53390c11 159 Gene3D G3DSA:3.40.1280.10 1 159 2.7E-66 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CLOST_2533 37d8b5c673e580c89b7be04d53390c11 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 4.5E-60 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 CLOST_2533 37d8b5c673e580c89b7be04d53390c11 159 PIRSF PIRSF004505 1 159 1.7E-55 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 CLOST_0988 7c689c70799467752c50c95a09223d67 374 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 18 362 27.145 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 CLOST_0988 7c689c70799467752c50c95a09223d67 374 Gene3D G3DSA:3.30.2110.10 20 190 2.5E-46 T 13-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 CLOST_0988 7c689c70799467752c50c95a09223d67 374 SUPERFAMILY SSF111342 12 289 9.15E-79 T 13-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 CLOST_0988 7c689c70799467752c50c95a09223d67 374 Pfam PF01888 CbiD 18 271 6.9E-84 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 CLOST_0988 7c689c70799467752c50c95a09223d67 374 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 25 362 6.7E-82 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 CLOST_0988 7c689c70799467752c50c95a09223d67 374 PIRSF PIRSF026782 14 368 3.0E-112 T 13-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 SUPERFAMILY SSF52540 155 393 2.25E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 Pfam PF02954 Bacterial regulatory protein, Fis family 424 462 1.7E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 370 379 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 180 193 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 Pfam PF00158 Sigma-54 interaction domain 156 323 6.9E-73 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 Gene3D G3DSA:1.10.10.60 411 465 3.2E-16 T 13-10-2018 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 243 258 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 SMART SM00382 176 320 8.0E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 Gene3D G3DSA:3.40.50.300 140 328 9.5E-68 T 13-10-2018 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 SUPERFAMILY SSF55785 17 112 4.6E-5 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 Gene3D G3DSA:3.30.450.20 11 120 2.4E-10 T 13-10-2018 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 Gene3D G3DSA:1.10.8.60 329 410 7.5E-24 T 13-10-2018 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 445 1.2E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 445 465 1.2E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_1081 365096a0c3ad65f3b85ac30b7fcb4555 465 SUPERFAMILY SSF46689 370 465 2.06E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_2370 398423e4d136c21eaff04de9c309bd9d 269 SMART SM00481 4 86 2.7E-6 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CLOST_2370 398423e4d136c21eaff04de9c309bd9d 269 SUPERFAMILY SSF89550 3 267 1.57E-48 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CLOST_2370 398423e4d136c21eaff04de9c309bd9d 269 Pfam PF02811 PHP domain 5 196 1.1E-15 T 13-10-2018 IPR004013 PHP domain GO:0003824 CLOST_2370 398423e4d136c21eaff04de9c309bd9d 269 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 241 5.6E-54 T 13-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CLOST_2370 398423e4d136c21eaff04de9c309bd9d 269 Gene3D G3DSA:3.20.20.140 2 263 3.7E-73 T 13-10-2018 CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 Gene3D G3DSA:3.40.50.300 79 224 7.2E-28 T 13-10-2018 CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 SMART SM00382 28 170 3.6E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 SMART SM00382 313 474 7.2E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 SUPERFAMILY SSF52540 3 186 2.04E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 Pfam PF00005 ABC transporter 305 429 1.5E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 Pfam PF00005 ABC transporter 23 65 2.9E-10 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 Gene3D G3DSA:3.40.50.300 251 509 1.3E-49 T 13-10-2018 CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 SUPERFAMILY SSF52540 272 485 5.16E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 ProSitePatterns PS00211 ABC transporters family signature. 98 112 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2459 98d9558d5751a8a80815816f02ed054e 544 Gene3D G3DSA:3.40.50.300 2 78 2.4E-14 T 13-10-2018 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SUPERFAMILY SSF47384 309 389 4.32E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Pfam PF00512 His Kinase A (phospho-acceptor) domain 324 388 2.8E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Gene3D G3DSA:3.40.50.2300 706 846 7.0E-36 T 13-10-2018 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Gene3D G3DSA:3.40.50.2300 565 698 7.2E-9 T 13-10-2018 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Gene3D G3DSA:1.10.287.130 295 386 2.4E-26 T 13-10-2018 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Gene3D G3DSA:3.40.190.10 34 259 1.4E-76 T 13-10-2018 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SUPERFAMILY SSF52172 567 696 1.27E-11 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Gene3D G3DSA:3.30.565.10 387 555 3.0E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Pfam PF00072 Response regulator receiver domain 722 833 1.4E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SUPERFAMILY SSF53850 44 262 7.25E-56 T 13-10-2018 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SUPERFAMILY SSF52172 720 837 2.56E-33 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 260 2.0E-49 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Gene3D G3DSA:1.20.120.160 854 965 1.1E-16 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 435 549 1.5E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SMART SM00062 43 263 6.8E-43 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SMART SM00448 720 833 6.2E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SMART SM00387 435 551 1.2E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Pfam PF01627 Hpt domain 878 948 3.3E-6 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 Gene3D G3DSA:3.40.190.10 129 222 1.4E-76 T 13-10-2018 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SUPERFAMILY SSF47226 818 946 1.05E-15 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 490 1.5E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 529 1.5E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 548 1.5E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 504 1.5E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SMART SM00388 323 388 1.5E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1047 ea1c0591fba051025f2c6f6f28292c49 965 SUPERFAMILY SSF55874 377 549 2.49E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0944 f2412d9e9131f10d7fda5e8bcf4ea522 129 Gene3D G3DSA:2.40.50.100 54 129 2.9E-26 T 13-10-2018 CLOST_0944 f2412d9e9131f10d7fda5e8bcf4ea522 129 Pfam PF00364 Biotin-requiring enzyme 63 127 1.6E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment CLOST_0944 f2412d9e9131f10d7fda5e8bcf4ea522 129 SUPERFAMILY SSF51230 54 128 4.58E-24 T 13-10-2018 IPR011053 Single hybrid motif CLOST_0944 f2412d9e9131f10d7fda5e8bcf4ea522 129 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 85 102 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_2157 ea7b8cb1eb2b88b97c2a25b858874f47 335 SMART SM00244 57 268 1.1E-12 T 13-10-2018 IPR001107 Band 7 domain CLOST_2157 ea7b8cb1eb2b88b97c2a25b858874f47 335 SUPERFAMILY SSF117892 133 270 4.84E-9 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily CLOST_2157 ea7b8cb1eb2b88b97c2a25b858874f47 335 Gene3D G3DSA:3.30.479.30 128 270 2.0E-6 T 13-10-2018 CLOST_2157 ea7b8cb1eb2b88b97c2a25b858874f47 335 Pfam PF01145 SPFH domain / Band 7 family 61 277 7.1E-19 T 13-10-2018 IPR001107 Band 7 domain CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 SUPERFAMILY SSF52540 4 207 5.95E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 Gene3D G3DSA:2.40.30.10 202 302 4.2E-28 T 13-10-2018 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 SMART SM00838 400 488 9.5E-6 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 SUPERFAMILY SSF54980 307 391 2.77E-14 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 5.3E-56 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 137 5.2E-24 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 Gene3D G3DSA:3.30.70.240 393 486 1.9E-133 T 13-10-2018 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 Gene3D G3DSA:3.40.50.300 4 200 5.4E-66 T 13-10-2018 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 SUPERFAMILY SSF54980 403 517 2.16E-30 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 603 2.8E-280 T 13-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 Gene3D G3DSA:2.40.50.250 487 603 1.9E-133 T 13-10-2018 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 SUPERFAMILY SSF50447 185 304 2.7E-26 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 Gene3D G3DSA:3.30.70.870 310 594 1.9E-133 T 13-10-2018 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 Pfam PF03144 Elongation factor Tu domain 2 221 293 3.4E-11 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 Pfam PF00679 Elongation factor G C-terminus 401 485 2.8E-25 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 PRINTS PR00315 GTP-binding elongation factor signature 73 83 2.4E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 PRINTS PR00315 GTP-binding elongation factor signature 53 61 2.4E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.4E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0868 d8ac29b964e3845a6183b2a3c6da3957 610 PRINTS PR00315 GTP-binding elongation factor signature 125 134 2.4E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0448 c01c82452d45da11ece5827780039864 138 SUPERFAMILY SSF51182 6 133 3.11E-34 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0448 c01c82452d45da11ece5827780039864 138 Pfam PF05523 WxcM-like, C-terminal 4 132 1.6E-46 T 13-10-2018 IPR008894 WxcM-like, C-terminal KEGG: 00523+5.3.2.3|MetaCyc: PWY-6953|MetaCyc: PWY-7688 CLOST_0448 c01c82452d45da11ece5827780039864 138 Gene3D G3DSA:2.60.120.10 1 138 1.7E-45 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0712 fd8319b177a5256ce6c7d6d7c64def01 447 Gene3D G3DSA:3.30.2290.10 1 213 2.0E-60 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal CLOST_0712 fd8319b177a5256ce6c7d6d7c64def01 447 Pfam PF01523 Putative modulator of DNA gyrase 22 309 2.3E-51 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CLOST_0712 fd8319b177a5256ce6c7d6d7c64def01 447 SUPERFAMILY SSF111283 4 447 3.92E-100 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 CLOST_1688 14681a8d72ba4a854ae63c2352f6bd6a 326 Gene3D G3DSA:3.90.1640.10 1 199 1.4E-64 T 13-10-2018 CLOST_1688 14681a8d72ba4a854ae63c2352f6bd6a 326 Gene3D G3DSA:3.10.310.30 202 322 1.1E-33 T 13-10-2018 CLOST_1688 14681a8d72ba4a854ae63c2352f6bd6a 326 SUPERFAMILY SSF64182 12 302 1.83E-61 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily CLOST_1688 14681a8d72ba4a854ae63c2352f6bd6a 326 Pfam PF01368 DHH family 14 158 2.7E-16 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_1688 14681a8d72ba4a854ae63c2352f6bd6a 326 Pfam PF02272 DHHA1 domain 239 314 5.4E-12 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 Gene3D G3DSA:3.40.50.2300 161 332 7.9E-13 T 13-10-2018 CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 409 568 9.4E-35 T 13-10-2018 IPR000160 GGDEF domain CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 Pfam PF04392 ABC transporter substrate binding protein 84 332 5.3E-8 T 13-10-2018 IPR007487 ABC transporter, substrate-binding protein CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 Gene3D G3DSA:3.20.20.450 583 833 1.2E-88 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 SMART SM00052 579 825 3.0E-94 T 13-10-2018 IPR001633 EAL domain CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 Pfam PF00990 Diguanylate cyclase, GGDEF domain 413 565 1.7E-41 T 13-10-2018 IPR000160 GGDEF domain CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 SMART SM00267 401 569 4.9E-51 T 13-10-2018 IPR000160 GGDEF domain CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 SUPERFAMILY SSF55073 417 571 1.1E-42 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 SUPERFAMILY SSF141868 584 832 3.79E-83 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 Gene3D G3DSA:3.30.70.270 406 582 3.1E-54 T 13-10-2018 CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 Pfam PF00563 EAL domain 586 820 3.8E-65 T 13-10-2018 IPR001633 EAL domain CLOST_2065 1474328b1aacefd8b333daccbd421e00 844 Gene3D G3DSA:3.40.50.2300 104 315 7.9E-13 T 13-10-2018 CLOST_1370 205ea6595f28f94aee8cf2020a05dd57 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 9.3E-23 T 13-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CLOST_1370 205ea6595f28f94aee8cf2020a05dd57 97 SUPERFAMILY SSF75471 1 95 7.19E-26 T 13-10-2018 IPR035920 YhbY-like superfamily CLOST_1370 205ea6595f28f94aee8cf2020a05dd57 97 SMART SM01103 2 85 5.4E-30 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CLOST_1370 205ea6595f28f94aee8cf2020a05dd57 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 3.6E-18 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CLOST_1370 205ea6595f28f94aee8cf2020a05dd57 97 Gene3D G3DSA:3.30.110.60 1 97 4.1E-31 T 13-10-2018 IPR035920 YhbY-like superfamily CLOST_1370 205ea6595f28f94aee8cf2020a05dd57 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 97 4.0E-19 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CLOST_2265 59426efb1094bd807b965f36ee5d55e8 515 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CLOST_2265 59426efb1094bd807b965f36ee5d55e8 515 SUPERFAMILY SSF52540 71 356 8.9E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2265 59426efb1094bd807b965f36ee5d55e8 515 Gene3D G3DSA:3.40.50.300 2 205 2.5E-77 T 13-10-2018 CLOST_2265 59426efb1094bd807b965f36ee5d55e8 515 Pfam PF00271 Helicase conserved C-terminal domain 226 335 4.4E-31 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_2265 59426efb1094bd807b965f36ee5d55e8 515 SMART SM00487 21 218 2.8E-66 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_2265 59426efb1094bd807b965f36ee5d55e8 515 SMART SM00490 254 335 6.0E-38 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_2265 59426efb1094bd807b965f36ee5d55e8 515 Gene3D G3DSA:3.40.50.300 206 448 1.4E-54 T 13-10-2018 CLOST_2265 59426efb1094bd807b965f36ee5d55e8 515 Pfam PF00270 DEAD/DEAH box helicase 26 190 4.6E-50 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Gene3D G3DSA:3.40.50.300 177 351 3.4E-73 T 13-10-2018 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 SUPERFAMILY SSF52156 458 587 7.72E-39 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Gene3D G3DSA:1.10.10.2480 1 85 1.2E-19 T 13-10-2018 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 SUPERFAMILY SSF50447 582 678 4.78E-30 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 99 678 1.0E-256 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Gene3D G3DSA:3.40.50.10050 475 581 2.3E-42 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Pfam PF11987 Translation-initiation factor 2 465 570 6.0E-40 T 13-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 ProSitePatterns PS01176 Initiation factor 2 signature. 631 653 - T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Pfam PF00009 Elongation factor Tu GTP binding domain 185 341 3.5E-34 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 185 339 6.2E-36 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 105 154 1.9E-11 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 53 1.0E-15 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Gene3D G3DSA:2.40.30.10 352 469 4.2E-44 T 13-10-2018 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 SUPERFAMILY SSF52540 166 352 9.42E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 678 17.22 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 Gene3D G3DSA:2.40.30.10 582 679 2.5E-32 T 13-10-2018 CLOST_1690 a7e8e7fd459fcf094a871f8eaa2c37f5 679 SUPERFAMILY SSF50447 352 435 2.95E-27 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_0024 c4e6c006e6fd311eff8b06900ebd1100 549 PIRSF PIRSF010386 3 549 1.7E-137 T 13-10-2018 IPR012166 Uncharacterised protein family RocB CLOST_0024 c4e6c006e6fd311eff8b06900ebd1100 549 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 177 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CLOST_0024 c4e6c006e6fd311eff8b06900ebd1100 549 SUPERFAMILY SSF53187 7 536 2.29E-26 T 13-10-2018 CLOST_0024 c4e6c006e6fd311eff8b06900ebd1100 549 Gene3D G3DSA:3.40.630.10 7 235 3.5E-32 T 13-10-2018 CLOST_0024 c4e6c006e6fd311eff8b06900ebd1100 549 Pfam PF01546 Peptidase family M20/M25/M40 131 439 2.3E-13 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 CLOST_2393 b26446f87ee60096177df596f069ee39 240 SMART SM00100 26 144 4.9E-20 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_2393 b26446f87ee60096177df596f069ee39 240 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 205 220 2.0E-5 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_2393 b26446f87ee60096177df596f069ee39 240 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 189 205 2.0E-5 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_2393 b26446f87ee60096177df596f069ee39 240 Gene3D G3DSA:2.60.120.1460 31 240 2.1E-54 T 13-10-2018 CLOST_2393 b26446f87ee60096177df596f069ee39 240 Pfam PF13545 Crp-like helix-turn-helix domain 165 239 2.5E-14 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_2393 b26446f87ee60096177df596f069ee39 240 SUPERFAMILY SSF51206 20 157 4.98E-34 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like CLOST_2393 b26446f87ee60096177df596f069ee39 240 SMART SM00419 183 232 5.9E-7 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_2393 b26446f87ee60096177df596f069ee39 240 Pfam PF00027 Cyclic nucleotide-binding domain 45 131 4.7E-21 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_2393 b26446f87ee60096177df596f069ee39 240 SUPERFAMILY SSF46785 162 239 1.99E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2574 5ba2a478abd0e36e8d1a2b73ad9d9027 203 SUPERFAMILY SSF75169 104 197 9.18E-13 T 13-10-2018 IPR027396 DsrEFH-like CLOST_2574 5ba2a478abd0e36e8d1a2b73ad9d9027 203 Pfam PF01206 Sulfurtransferase TusA 4 68 2.1E-13 T 13-10-2018 IPR001455 TusA-like domain CLOST_2574 5ba2a478abd0e36e8d1a2b73ad9d9027 203 Pfam PF02635 DsrE/DsrF-like family 133 196 2.1E-4 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein CLOST_2574 5ba2a478abd0e36e8d1a2b73ad9d9027 203 TIGRFAM TIGR03527 selenium_YedF: selenium metabolism protein YedF 6 196 1.1E-67 T 13-10-2018 IPR019870 Selenium metabolism protein YedF CLOST_2574 5ba2a478abd0e36e8d1a2b73ad9d9027 203 Gene3D G3DSA:3.30.110.40 4 95 1.3E-18 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_2574 5ba2a478abd0e36e8d1a2b73ad9d9027 203 SUPERFAMILY SSF64307 4 68 4.84E-12 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_2196 ab9962a926ace5e196339892e1a6dc13 94 ProSitePatterns PS00050 Ribosomal protein L23 signature. 76 91 - T 13-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2196 ab9962a926ace5e196339892e1a6dc13 94 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 94 21.615 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CLOST_2196 ab9962a926ace5e196339892e1a6dc13 94 SUPERFAMILY SSF54189 4 91 2.48E-31 T 13-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2196 ab9962a926ace5e196339892e1a6dc13 94 Pfam PF00276 Ribosomal protein L23 5 87 7.5E-34 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CLOST_2196 ab9962a926ace5e196339892e1a6dc13 94 Gene3D G3DSA:3.30.70.330 2 94 7.5E-33 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily CLOST_0237 d7e9c3fdf10452a6c53ba78cba117626 405 Gene3D G3DSA:1.20.1250.20 7 393 4.9E-39 T 13-10-2018 CLOST_0237 d7e9c3fdf10452a6c53ba78cba117626 405 SUPERFAMILY SSF103473 8 390 9.16E-47 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_0237 d7e9c3fdf10452a6c53ba78cba117626 405 Pfam PF07690 Major Facilitator Superfamily 14 332 1.5E-20 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOST_0452 22f9232666130ee75fb8ab200be7b76b 237 SUPERFAMILY SSF52540 14 234 1.43E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0452 22f9232666130ee75fb8ab200be7b76b 237 SMART SM00382 43 230 8.4E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0452 22f9232666130ee75fb8ab200be7b76b 237 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0452 22f9232666130ee75fb8ab200be7b76b 237 Gene3D G3DSA:3.40.50.300 12 237 2.2E-66 T 13-10-2018 CLOST_0452 22f9232666130ee75fb8ab200be7b76b 237 Pfam PF00005 ABC transporter 34 182 1.9E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0766 76a97c9d4bcb836935cf4039c37e18ce 160 Pfam PF03773 Predicted permease 36 156 3.0E-8 T 13-10-2018 IPR005524 Predicted permease DUF318 CLOST_0526 77ecd9d03bd9eee8b3b70c942ecf8c9f 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 44.936 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CLOST_0526 77ecd9d03bd9eee8b3b70c942ecf8c9f 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 250 5.0E-104 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CLOST_0526 77ecd9d03bd9eee8b3b70c942ecf8c9f 252 SUPERFAMILY SSF51366 1 250 5.1E-80 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CLOST_0526 77ecd9d03bd9eee8b3b70c942ecf8c9f 252 Gene3D G3DSA:3.20.20.70 2 252 4.5E-104 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0526 77ecd9d03bd9eee8b3b70c942ecf8c9f 252 Pfam PF00977 Histidine biosynthesis protein 5 232 4.8E-84 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 CLOST_1013 2ac79ce011cd9ca7c2241b2f3cbcd137 294 SUPERFAMILY SSF103481 35 124 7.85E-11 T 13-10-2018 CLOST_1013 2ac79ce011cd9ca7c2241b2f3cbcd137 294 Pfam PF00892 EamA-like transporter family 1 122 5.4E-12 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_1013 2ac79ce011cd9ca7c2241b2f3cbcd137 294 Pfam PF00892 EamA-like transporter family 136 281 5.7E-15 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_1013 2ac79ce011cd9ca7c2241b2f3cbcd137 294 SUPERFAMILY SSF103481 206 282 1.1E-7 T 13-10-2018 CLOST_0019 b1986d3ede17b2e8825117ff3288f3ea 491 Pfam PF01425 Amidase 27 468 1.2E-156 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOST_0019 b1986d3ede17b2e8825117ff3288f3ea 491 Gene3D G3DSA:3.90.1300.10 4 485 4.3E-193 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOST_0019 b1986d3ede17b2e8825117ff3288f3ea 491 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 15 478 4.9E-189 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOST_0019 b1986d3ede17b2e8825117ff3288f3ea 491 SUPERFAMILY SSF75304 5 479 3.27E-154 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOST_0019 b1986d3ede17b2e8825117ff3288f3ea 491 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 13 479 89.458 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CLOST_1329 3c908c7afc11f571b3f35cd6557b2348 412 ProSitePatterns PS01276 Peptidase family U32 signature. 163 181 - T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CLOST_1329 3c908c7afc11f571b3f35cd6557b2348 412 Pfam PF01136 Peptidase family U32 76 307 1.3E-96 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CLOST_1329 3c908c7afc11f571b3f35cd6557b2348 412 Gene3D G3DSA:2.40.30.10 320 407 3.8E-17 T 13-10-2018 CLOST_1329 3c908c7afc11f571b3f35cd6557b2348 412 Pfam PF16325 Peptidase family U32 C-terminal domain 322 405 3.0E-18 T 13-10-2018 IPR032525 Peptidase family U32, C-terminal CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SUPERFAMILY SSF52172 4 133 8.4E-33 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Pfam PF00072 Response regulator receiver domain 5 116 1.1E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Pfam PF00563 EAL domain 585 812 3.4E-61 T 13-10-2018 IPR001633 EAL domain CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SMART SM00267 390 557 4.3E-5 T 13-10-2018 IPR000160 GGDEF domain CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Gene3D G3DSA:3.30.450.20 153 262 5.0E-14 T 13-10-2018 CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SMART SM00052 568 817 1.4E-80 T 13-10-2018 IPR001633 EAL domain CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Gene3D G3DSA:3.30.450.20 270 387 1.5E-20 T 13-10-2018 CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Gene3D G3DSA:3.30.70.270 400 574 1.4E-13 T 13-10-2018 CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Gene3D G3DSA:3.40.50.12740 1 152 1.2E-32 T 13-10-2018 CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SUPERFAMILY SSF55785 166 260 3.22E-15 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SUPERFAMILY SSF55785 279 392 2.42E-16 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Pfam PF08447 PAS fold 297 384 7.0E-11 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Pfam PF08447 PAS fold 170 245 7.8E-9 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SUPERFAMILY SSF55073 407 538 9.42E-10 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SMART SM00086 217 259 0.16 T 13-10-2018 IPR001610 PAC motif CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SMART SM00086 348 390 0.16 T 13-10-2018 IPR001610 PAC motif CLOST_1048 b362261e9243f06557abc3e0efc919df 823 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 290 397 2.2E-7 T 13-10-2018 IPR000014 PAS domain CLOST_1048 b362261e9243f06557abc3e0efc919df 823 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 169 266 7.8E-12 T 13-10-2018 IPR000014 PAS domain CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SMART SM00091 137 210 11.0 T 13-10-2018 IPR000014 PAS domain CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SMART SM00091 271 342 0.26 T 13-10-2018 IPR000014 PAS domain CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SUPERFAMILY SSF141868 579 822 2.48E-73 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Gene3D G3DSA:3.20.20.450 575 823 2.4E-75 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_1048 b362261e9243f06557abc3e0efc919df 823 SMART SM00448 3 115 3.4E-32 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1048 b362261e9243f06557abc3e0efc919df 823 Pfam PF00990 Diguanylate cyclase, GGDEF domain 402 537 5.4E-10 T 13-10-2018 IPR000160 GGDEF domain CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 179 196 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 Gene3D G3DSA:3.30.420.40 4 355 7.9E-133 T 13-10-2018 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 PIRSF PIRSF036458 1 355 4.6E-132 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 PRINTS PR00471 Acetate kinase family signature 5 16 1.6E-15 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 PRINTS PR00471 Acetate kinase family signature 274 287 1.6E-15 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 PRINTS PR00471 Acetate kinase family signature 179 200 1.6E-15 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 PRINTS PR00471 Acetate kinase family signature 297 313 1.6E-15 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 Pfam PF00871 Acetokinase family 5 343 8.7E-51 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 Hamap MF_00542 Probable butyrate kinase [buk]. 1 355 130.97 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 Gene3D G3DSA:3.30.420.40 137 332 7.9E-133 T 13-10-2018 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 SUPERFAMILY SSF53067 150 348 7.33E-46 T 13-10-2018 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 SUPERFAMILY SSF53067 4 172 3.89E-53 T 13-10-2018 CLOST_0757 f4efb582604917fa2526bb9c0a793386 355 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 4 353 1.7E-129 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_1169 24a52d8f5ae029081de43667c881b24c 451 Gene3D G3DSA:3.40.50.11600 320 449 8.3E-45 T 13-10-2018 CLOST_1169 24a52d8f5ae029081de43667c881b24c 451 Gene3D G3DSA:3.20.20.20 1 319 2.3E-89 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1169 24a52d8f5ae029081de43667c881b24c 451 Pfam PF04060 Putative Fe-S cluster 13 43 2.0E-11 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 CLOST_1169 24a52d8f5ae029081de43667c881b24c 451 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 65 443 2.0E-81 T 13-10-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 SUPERFAMILY SSF53271 73 306 5.0E-66 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 8 315 1.2E-127 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 Gene3D G3DSA:3.40.50.2020 151 291 2.8E-128 T 13-10-2018 CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 132 147 - T 13-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 3.3E-51 T 13-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 Gene3D G3DSA:3.40.50.2020 11 302 2.8E-128 T 13-10-2018 CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 Pfam PF14572 Phosphoribosyl synthetase-associated domain 206 314 3.6E-25 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 8 315 50.757 T 13-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CLOST_0473 2e51c13efe832f764c370bb478502ad7 318 SMART SM01400 8 124 1.3E-83 T 13-10-2018 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.5E-24 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.5E-24 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.5E-24 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 Pfam PF00203 Ribosomal protein S19 3 83 1.1E-35 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 5.1E-45 T 13-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 Gene3D G3DSA:3.30.860.10 1 93 2.2E-39 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 PIRSF PIRSF002144 1 93 5.7E-32 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 13-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 SUPERFAMILY SSF54570 3 84 1.57E-34 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2194 5da0e1fea621f849c341a2e6bf83205b 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.089 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1082 7a461eb93227c8e1b8f63d04563095fd 245 SUPERFAMILY SSF55120 1 245 1.42E-73 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1082 7a461eb93227c8e1b8f63d04563095fd 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 32.046 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1082 7a461eb93227c8e1b8f63d04563095fd 245 PIRSF PIRSF001430 1 245 1.8E-72 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1082 7a461eb93227c8e1b8f63d04563095fd 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 239 2.7E-58 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1082 7a461eb93227c8e1b8f63d04563095fd 245 Gene3D G3DSA:3.30.70.660 107 244 2.1E-42 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 CLOST_1082 7a461eb93227c8e1b8f63d04563095fd 245 Pfam PF01416 tRNA pseudouridine synthase 7 103 3.7E-7 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1082 7a461eb93227c8e1b8f63d04563095fd 245 Pfam PF01416 tRNA pseudouridine synthase 144 245 1.6E-24 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1082 7a461eb93227c8e1b8f63d04563095fd 245 Gene3D G3DSA:3.30.70.580 1 106 3.8E-32 T 13-10-2018 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 154 44.679 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 156 6.7E-49 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 SUPERFAMILY SSF53098 1 156 1.33E-49 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 Gene3D G3DSA:3.30.420.10 1 160 6.4E-54 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 151 2.9E-53 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 148 - T 13-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 8.7E-30 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 8.7E-30 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 8.7E-30 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 8.7E-30 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CLOST_1318 d23d8950e9aa9d205af0f880b5a090f7 163 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 8.7E-30 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 254 333 5.0E-25 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 SUPERFAMILY SSF46785 261 331 5.65E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 Gene3D G3DSA:3.40.50.300 24 185 4.4E-42 T 13-10-2018 CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 165.708 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 SUPERFAMILY SSF52540 24 252 1.78E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 Gene3D G3DSA:1.10.8.60 186 259 1.7E-31 T 13-10-2018 CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 15 239 5.6E-117 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 28 330 5.1E-147 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 SMART SM00382 55 183 5.0E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 Gene3D G3DSA:1.10.10.10 261 333 2.2E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1316 760f8b886886299f7726edc21f5cf2ab 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 257 330 6.6E-34 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CLOST_2588 31b621c6c961ce4182d50207afefcfab 73 Pfam PF01809 Haemolytic domain 7 71 6.2E-32 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor CLOST_2588 31b621c6c961ce4182d50207afefcfab 73 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 20 73 7.0E-18 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor CLOST_2588 31b621c6c961ce4182d50207afefcfab 73 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 9 71 3.7E-31 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor CLOST_2588 31b621c6c961ce4182d50207afefcfab 73 SMART SM01234 5 72 6.3E-47 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor CLOST_2588 31b621c6c961ce4182d50207afefcfab 73 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 5 73 25.35 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor CLOST_1392 37d2924440339407258f292b1b339c2d 931 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 362 6.9E-50 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CLOST_1392 37d2924440339407258f292b1b339c2d 931 SUPERFAMILY SSF56601 863 912 1.97E-6 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like CLOST_1392 37d2924440339407258f292b1b339c2d 931 SUPERFAMILY SSF56601 329 794 2.33E-71 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like CLOST_1392 37d2924440339407258f292b1b339c2d 931 Pfam PF00905 Penicillin binding protein transpeptidase domain 862 904 1.4E-5 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CLOST_1392 37d2924440339407258f292b1b339c2d 931 Pfam PF00905 Penicillin binding protein transpeptidase domain 425 796 2.2E-51 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CLOST_1392 37d2924440339407258f292b1b339c2d 931 Gene3D G3DSA:3.40.710.10 852 915 1.7E-9 T 13-10-2018 CLOST_1392 37d2924440339407258f292b1b339c2d 931 Gene3D G3DSA:3.90.1310.30 194 373 2.8E-26 T 13-10-2018 CLOST_1392 37d2924440339407258f292b1b339c2d 931 Gene3D G3DSA:3.90.1310.30 48 168 2.2E-9 T 13-10-2018 CLOST_1392 37d2924440339407258f292b1b339c2d 931 SUPERFAMILY SSF56519 49 377 1.31E-41 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 SMART SM00279 184 219 1.5E-17 T 13-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Gene3D G3DSA:1.10.150.20 185 257 7.0E-104 T 13-10-2018 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Pfam PF00476 DNA polymerase family A 511 886 8.5E-157 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 ProSitePatterns PS00447 DNA polymerase family A signature. 714 733 - T 13-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 SUPERFAMILY SSF88723 13 180 1.35E-55 T 13-10-2018 IPR029060 PIN-like domain superfamily CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 SMART SM00482 646 852 8.4E-113 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 TIGRFAM TIGR00593 pola: DNA polymerase I 16 888 0.0 T 13-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 SMART SM00475 13 272 9.9E-138 T 13-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 SUPERFAMILY SSF53098 342 479 1.9E-25 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 SUPERFAMILY SSF56672 482 887 1.67E-158 T 13-10-2018 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 183 276 1.0E-32 T 13-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Gene3D G3DSA:1.20.1060.10 504 617 5.2E-45 T 13-10-2018 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Gene3D G3DSA:1.10.150.20 669 812 7.5E-105 T 13-10-2018 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 SUPERFAMILY SSF47807 182 295 1.32E-34 T 13-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 660 683 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 751 762 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 615 637 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 638 653 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 835 848 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 690 703 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 714 739 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 805 821 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 773 784 3.7E-77 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Gene3D G3DSA:3.40.50.1010 16 288 7.0E-104 T 13-10-2018 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Gene3D G3DSA:3.30.70.370 622 884 7.5E-105 T 13-10-2018 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Gene3D G3DSA:3.30.420.10 338 503 6.8E-34 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Pfam PF01612 3'-5' exonuclease 364 448 1.8E-6 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CLOST_1407 7d62bdaf731f290544e8b2f34fca5010 888 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 16 180 3.0E-55 T 13-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CLOST_0154 68af341fcc3a65a7dd9c9acdee3cb0e0 301 SUPERFAMILY SSF103481 42 142 1.31E-12 T 13-10-2018 CLOST_0154 68af341fcc3a65a7dd9c9acdee3cb0e0 301 SUPERFAMILY SSF103481 189 291 2.88E-11 T 13-10-2018 CLOST_0154 68af341fcc3a65a7dd9c9acdee3cb0e0 301 Pfam PF00892 EamA-like transporter family 7 139 8.8E-17 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_0154 68af341fcc3a65a7dd9c9acdee3cb0e0 301 Pfam PF00892 EamA-like transporter family 154 287 9.5E-20 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_0790 539d0fea5a2e4d0fcc84cc40c5811376 584 SUPERFAMILY SSF52540 328 575 4.6E-84 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0790 539d0fea5a2e4d0fcc84cc40c5811376 584 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0790 539d0fea5a2e4d0fcc84cc40c5811376 584 Gene3D G3DSA:1.20.1560.10 1 321 6.0E-82 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0790 539d0fea5a2e4d0fcc84cc40c5811376 584 Pfam PF00664 ABC transporter transmembrane region 18 293 1.6E-34 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 CLOST_0790 539d0fea5a2e4d0fcc84cc40c5811376 584 SUPERFAMILY SSF90123 3 319 6.28E-69 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0790 539d0fea5a2e4d0fcc84cc40c5811376 584 Gene3D G3DSA:3.40.50.300 334 581 3.0E-80 T 13-10-2018 CLOST_0790 539d0fea5a2e4d0fcc84cc40c5811376 584 SMART SM00382 365 551 1.0E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0790 539d0fea5a2e4d0fcc84cc40c5811376 584 Pfam PF00005 ABC transporter 356 505 3.6E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0651 be6385ad6743a98ab59000a5cbe8317f 428 PIRSF PIRSF000505 1 427 5.7E-131 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CLOST_0651 be6385ad6743a98ab59000a5cbe8317f 428 SUPERFAMILY SSF55205 4 424 4.84E-110 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CLOST_0651 be6385ad6743a98ab59000a5cbe8317f 428 Gene3D G3DSA:3.65.10.10 21 236 8.7E-127 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 CLOST_0651 be6385ad6743a98ab59000a5cbe8317f 428 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 13 421 2.7E-115 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CLOST_0651 be6385ad6743a98ab59000a5cbe8317f 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 416 1.4E-106 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOST_0651 be6385ad6743a98ab59000a5cbe8317f 428 ProSitePatterns PS00885 EPSP synthase signature 2. 334 352 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CLOST_0651 be6385ad6743a98ab59000a5cbe8317f 428 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 9 423 31.68 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CLOST_0651 be6385ad6743a98ab59000a5cbe8317f 428 Gene3D G3DSA:3.65.10.10 12 417 8.7E-127 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 CLOST_0612 f1323184ffb7590912f9976d173221ba 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 304 2.3E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0612 f1323184ffb7590912f9976d173221ba 307 Gene3D G3DSA:1.10.3720.10 78 306 4.1E-34 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0612 f1323184ffb7590912f9976d173221ba 307 SUPERFAMILY SSF161098 31 300 5.89E-33 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0612 f1323184ffb7590912f9976d173221ba 307 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 24 303 1.1E-77 T 13-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CLOST_0403 6f2654825435a7fdc20751576996b8a5 194 Pfam PF14014 Protein of unknown function (DUF4230) 42 191 1.1E-36 T 13-10-2018 IPR025324 Protein of unknown function DUF4230 CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 Pfam PF04715 Anthranilate synthase component I, N terminal region 10 135 1.6E-29 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 SUPERFAMILY SSF56322 15 441 5.49E-137 T 13-10-2018 IPR005801 ADC synthase GO:0009058 CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 Pfam PF00425 chorismate binding enzyme 180 433 5.5E-96 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 Gene3D G3DSA:3.60.120.10 2 442 1.9E-156 T 13-10-2018 IPR005801 ADC synthase GO:0009058 CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 88 436 3.6E-116 T 13-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 PRINTS PR00095 Anthranilate synthase component I signature 295 308 2.9E-16 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 PRINTS PR00095 Anthranilate synthase component I signature 281 294 2.9E-16 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 PRINTS PR00095 Anthranilate synthase component I signature 390 404 2.9E-16 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1763 04faf44080b9aa2fce4699da240582a4 451 PRINTS PR00095 Anthranilate synthase component I signature 375 389 2.9E-16 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 PIRSF PIRSF006439 1 593 1.3E-224 T 13-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 573 584 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 Gene3D G3DSA:3.40.50.970 1 181 7.0E-57 T 13-10-2018 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 363 510 6.1E-27 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 SUPERFAMILY SSF54862 522 589 1.7E-14 T 13-10-2018 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 Pfam PF12838 4Fe-4S dicluster domain 542 587 2.5E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 Gene3D G3DSA:3.30.70.20 519 593 9.1E-11 T 13-10-2018 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 SUPERFAMILY SSF52922 222 298 2.92E-6 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 1 588 1.0E-209 T 13-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 Gene3D G3DSA:3.40.50.970 341 518 1.5E-21 T 13-10-2018 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 182 1.5E-16 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 SUPERFAMILY SSF52518 334 519 1.67E-32 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 SUPERFAMILY SSF52518 3 225 5.89E-60 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_0205 b21fec4fc3798b6e4a1a781aacddd978 593 Gene3D G3DSA:3.40.50.920 214 318 2.7E-6 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_0392 88c9259ea0b067aaff50cf7618688177 459 Pfam PF00854 POT family 114 207 1.4E-14 T 13-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 CLOST_0392 88c9259ea0b067aaff50cf7618688177 459 Pfam PF00854 POT family 227 423 1.5E-22 T 13-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 CLOST_0392 88c9259ea0b067aaff50cf7618688177 459 Gene3D G3DSA:1.20.1250.20 226 458 3.2E-41 T 13-10-2018 CLOST_0392 88c9259ea0b067aaff50cf7618688177 459 Gene3D G3DSA:1.20.1250.20 3 225 8.7E-41 T 13-10-2018 CLOST_0392 88c9259ea0b067aaff50cf7618688177 459 SUPERFAMILY SSF103473 9 440 1.57E-33 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_1051 229ac280deab1cf6a4337aac97f546bf 561 Pfam PF01966 HD domain 171 293 3.1E-17 T 13-10-2018 IPR006674 HD domain CLOST_1051 229ac280deab1cf6a4337aac97f546bf 561 SUPERFAMILY SSF109604 171 334 8.94E-26 T 13-10-2018 CLOST_1051 229ac280deab1cf6a4337aac97f546bf 561 Gene3D G3DSA:1.10.3210.10 149 340 4.5E-48 T 13-10-2018 CLOST_0187 549539f3acebb3f76b4f9b31eb9f5c34 129 Gene3D G3DSA:3.30.700.10 13 129 4.7E-21 T 13-10-2018 CLOST_0187 549539f3acebb3f76b4f9b31eb9f5c34 129 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site CLOST_0187 549539f3acebb3f76b4f9b31eb9f5c34 129 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 32 4.6E-11 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site CLOST_0187 549539f3acebb3f76b4f9b31eb9f5c34 129 SUPERFAMILY SSF54523 13 121 1.8E-17 T 13-10-2018 CLOST_0187 549539f3acebb3f76b4f9b31eb9f5c34 129 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 33 2.6E-10 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site CLOST_1850 318041aded537e5897d6cf584f60c4aa 250 SUPERFAMILY SSF81606 3 249 2.09E-71 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1850 318041aded537e5897d6cf584f60c4aa 250 SMART SM00331 16 250 6.2E-39 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1850 318041aded537e5897d6cf584f60c4aa 250 SMART SM00332 1 248 1.7E-37 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1850 318041aded537e5897d6cf584f60c4aa 250 Pfam PF13672 Protein phosphatase 2C 19 212 1.1E-14 T 13-10-2018 CLOST_1850 318041aded537e5897d6cf584f60c4aa 250 Gene3D G3DSA:3.60.40.10 1 250 1.9E-78 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1123 2d3a80482d010dc7f45025732bd966bc 216 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 16 31 - T 13-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 CLOST_1123 2d3a80482d010dc7f45025732bd966bc 216 SMART SM00882 4 215 1.0E-69 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 CLOST_1123 2d3a80482d010dc7f45025732bd966bc 216 Gene3D G3DSA:3.40.1080.10 1 216 8.4E-82 T 13-10-2018 CLOST_1123 2d3a80482d010dc7f45025732bd966bc 216 Pfam PF01144 Coenzyme A transferase 10 214 1.8E-65 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 CLOST_1123 2d3a80482d010dc7f45025732bd966bc 216 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 4 214 5.5E-68 T 13-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CLOST_1123 2d3a80482d010dc7f45025732bd966bc 216 SUPERFAMILY SSF100950 2 215 1.52E-77 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 423 1668 0.0 T 13-10-2018 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Gene3D G3DSA:3.30.1490.20 119 191 1.2E-12 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Gene3D G3DSA:3.30.1330.10 1069 1232 3.1E-29 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SMART SM01209 101 295 2.4E-90 T 13-10-2018 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 37.862 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SMART SM01210 329 422 3.2E-39 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SUPERFAMILY SSF56042 864 1030 8.22E-39 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 289 296 - T 13-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Gene3D G3DSA:3.90.650.10 851 1030 4.2E-48 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Gene3D G3DSA:3.30.470.20 192 328 1.2E-47 T 13-10-2018 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SUPERFAMILY SSF51246 328 420 1.52E-26 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SUPERFAMILY SSF55326 1054 1234 1.55E-36 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SUPERFAMILY SSF56042 1238 1372 1.79E-9 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1405 1667 3.1E-86 T 13-10-2018 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Gene3D G3DSA:3.40.50.20 2 93 2.3E-35 T 13-10-2018 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Gene3D G3DSA:1.10.8.750 585 640 1.1E-5 T 13-10-2018 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Gene3D G3DSA:3.40.50.880 1351 1662 3.1E-82 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 420 4.7E-144 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SMART SM01211 1405 1668 3.1E-109 T 13-10-2018 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SUPERFAMILY SSF52440 1 101 7.05E-34 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SUPERFAMILY SSF52317 1403 1661 1.64E-68 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.8E-33 T 13-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 295 7.4E-60 T 13-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 419 1.5E-26 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SUPERFAMILY SSF55326 624 854 4.19E-29 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Pfam PF02769 AIR synthase related protein, C-terminal domain 864 1014 3.4E-22 T 13-10-2018 IPR010918 PurM-like, C-terminal domain CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 SUPERFAMILY SSF56059 102 344 1.3E-43 T 13-10-2018 CLOST_0339 88e5030d8fcf0ec824f2a443e98b56ca 1669 Gene3D G3DSA:3.90.600.10 329 432 1.6E-31 T 13-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 SUPERFAMILY SSF46785 438 506 6.53E-10 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 Pfam PF09106 Elongation factor SelB, winged helix 446 499 7.5E-11 T 13-10-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 Gene3D G3DSA:3.40.50.300 2 170 7.0E-49 T 13-10-2018 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 29 44 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 Pfam PF03144 Elongation factor Tu domain 2 194 260 3.5E-10 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 Pfam PF09107 Elongation factor SelB, winged helix 578 622 2.3E-17 T 13-10-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 Gene3D G3DSA:1.10.10.2770 441 563 1.3E-19 T 13-10-2018 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 PRINTS PR00315 GTP-binding elongation factor signature 73 84 3.8E-6 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 PRINTS PR00315 GTP-binding elongation factor signature 5 18 3.8E-6 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 PRINTS PR00315 GTP-binding elongation factor signature 57 67 3.8E-6 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 Gene3D G3DSA:1.10.10.10 567 623 4.2E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 SUPERFAMILY SSF52540 3 170 1.77E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 SUPERFAMILY SSF50465 266 361 3.42E-27 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 SUPERFAMILY SSF50447 175 265 6.68E-22 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 134 6.9E-17 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 Gene3D G3DSA:2.40.30.10 177 291 2.3E-27 T 13-10-2018 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 Pfam PF00009 Elongation factor Tu GTP binding domain 3 167 8.4E-33 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 4 622 1.7E-110 T 13-10-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CLOST_1357 dc7bb8a67c007d3aa9a735b554318b0c 627 SUPERFAMILY SSF46785 575 622 3.26E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0793 5cab9cb2710ef6bfc87a57717901aa98 181 SMART SM00450 57 173 1.6E-16 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_0793 5cab9cb2710ef6bfc87a57717901aa98 181 Pfam PF00581 Rhodanese-like domain 57 169 5.4E-16 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_0793 5cab9cb2710ef6bfc87a57717901aa98 181 Gene3D G3DSA:3.40.250.10 36 176 5.8E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_0793 5cab9cb2710ef6bfc87a57717901aa98 181 SUPERFAMILY SSF52821 47 175 1.57E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 PIRSF PIRSF039072 2 464 7.4E-262 T 13-10-2018 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 Gene3D G3DSA:1.10.1140.10 349 465 3.3E-58 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 76 1.1E-20 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 SMART SM00382 145 331 5.2E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 SUPERFAMILY SSF52540 80 351 5.57E-95 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 SUPERFAMILY SSF50615 4 77 1.7E-24 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 SUPERFAMILY SSF47917 349 463 2.56E-53 T 13-10-2018 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 Hamap MF_01347 ATP synthase subunit beta [atpB]. 4 464 58.046 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 133 346 1.2E-67 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 337 346 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 6 463 1.4E-258 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 Gene3D G3DSA:3.40.50.300 79 348 3.3E-118 T 13-10-2018 CLOST_2116 ff246de85e134bda6a59d179ca21bac8 465 Gene3D G3DSA:2.40.10.170 3 78 4.3E-29 T 13-10-2018 CLOST_1214 cd7110de146371c2106da02045466a1b 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 1.2E-18 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_1214 cd7110de146371c2106da02045466a1b 338 SUPERFAMILY SSF53822 64 335 4.86E-51 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_1214 cd7110de146371c2106da02045466a1b 338 Gene3D G3DSA:3.40.50.2300 64 313 1.4E-51 T 13-10-2018 CLOST_1214 cd7110de146371c2106da02045466a1b 338 SUPERFAMILY SSF47413 4 63 3.48E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_1214 cd7110de146371c2106da02045466a1b 338 Pfam PF13377 Periplasmic binding protein-like domain 173 335 7.2E-28 T 13-10-2018 CLOST_1214 cd7110de146371c2106da02045466a1b 338 Gene3D G3DSA:3.40.50.2300 165 296 1.4E-51 T 13-10-2018 CLOST_1214 cd7110de146371c2106da02045466a1b 338 SMART SM00354 4 74 1.2E-28 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_1214 cd7110de146371c2106da02045466a1b 338 Gene3D G3DSA:1.10.260.40 3 62 2.2E-21 T 13-10-2018 CLOST_1214 cd7110de146371c2106da02045466a1b 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 1.8E-6 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_1214 cd7110de146371c2106da02045466a1b 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 6 16 1.8E-6 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_0678 63818cd5d3aef4824dc26e35a8d0e4cd 90 Gene3D G3DSA:3.30.70.1710 1 89 1.9E-38 T 13-10-2018 CLOST_0678 63818cd5d3aef4824dc26e35a8d0e4cd 90 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 20 39 - T 13-10-2018 IPR020808 Bacterial microcompartments protein, conserved site CLOST_0678 63818cd5d3aef4824dc26e35a8d0e4cd 90 SMART SM00877 2 78 4.0E-36 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0678 63818cd5d3aef4824dc26e35a8d0e4cd 90 SUPERFAMILY SSF143414 1 88 1.57E-31 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0678 63818cd5d3aef4824dc26e35a8d0e4cd 90 Pfam PF00936 BMC domain 3 78 2.5E-29 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0678 63818cd5d3aef4824dc26e35a8d0e4cd 90 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 2 48 4.0E-13 T 13-10-2018 CLOST_1932 a21c689aede1d56102316bc4a814a5ec 475 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 86 1.2E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_1932 a21c689aede1d56102316bc4a814a5ec 475 Gene3D G3DSA:3.90.1150.10 99 455 2.4E-89 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1932 a21c689aede1d56102316bc4a814a5ec 475 Gene3D G3DSA:3.40.640.10 134 353 2.4E-89 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1932 a21c689aede1d56102316bc4a814a5ec 475 SUPERFAMILY SSF53383 91 456 4.46E-78 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1932 a21c689aede1d56102316bc4a814a5ec 475 SUPERFAMILY SSF46785 19 90 4.21E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1932 a21c689aede1d56102316bc4a814a5ec 475 SMART SM00345 27 86 3.7E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_1932 a21c689aede1d56102316bc4a814a5ec 475 Pfam PF00155 Aminotransferase class I and II 110 449 2.5E-21 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_1932 a21c689aede1d56102316bc4a814a5ec 475 Gene3D G3DSA:1.10.10.10 14 87 3.6E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 4 443 6.8E-127 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 SUPERFAMILY SSF53623 95 304 6.41E-48 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 SUPERFAMILY SSF53244 306 444 1.9E-40 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 Gene3D G3DSA:3.40.1190.10 93 306 5.1E-59 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 Pfam PF08245 Mur ligase middle domain 109 286 3.5E-35 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 Gene3D G3DSA:3.40.50.720 1 92 3.0E-13 T 13-10-2018 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 Pfam PF02875 Mur ligase family, glutamate ligase domain 307 356 3.9E-8 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 Gene3D G3DSA:3.90.190.20 312 445 1.4E-44 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 3 446 32.929 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_1897 6b3df323535faac525f4e1a9e27ed63a 446 SUPERFAMILY SSF51984 4 92 6.8E-10 T 13-10-2018 CLOST_0126 83d893e0817825149819b0064ebd0322 688 SUPERFAMILY SSF103190 107 194 6.08E-9 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0126 83d893e0817825149819b0064ebd0322 688 SMART SM00267 483 645 2.0E-34 T 13-10-2018 IPR000160 GGDEF domain CLOST_0126 83d893e0817825149819b0064ebd0322 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 361 489 3.4E-11 T 13-10-2018 IPR000014 PAS domain CLOST_0126 83d893e0817825149819b0064ebd0322 688 Pfam PF13426 PAS domain 375 481 1.6E-6 T 13-10-2018 IPR000014 PAS domain CLOST_0126 83d893e0817825149819b0064ebd0322 688 SUPERFAMILY SSF55785 354 479 1.92E-12 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0126 83d893e0817825149819b0064ebd0322 688 Pfam PF02743 Cache domain 66 271 8.9E-27 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0126 83d893e0817825149819b0064ebd0322 688 Gene3D G3DSA:3.30.450.20 94 190 9.4E-41 T 13-10-2018 CLOST_0126 83d893e0817825149819b0064ebd0322 688 Gene3D G3DSA:3.30.450.20 372 481 2.5E-19 T 13-10-2018 CLOST_0126 83d893e0817825149819b0064ebd0322 688 Gene3D G3DSA:3.30.450.20 191 281 9.4E-41 T 13-10-2018 CLOST_0126 83d893e0817825149819b0064ebd0322 688 SUPERFAMILY SSF55073 499 638 1.1E-30 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0126 83d893e0817825149819b0064ebd0322 688 Pfam PF00990 Diguanylate cyclase, GGDEF domain 494 639 4.8E-31 T 13-10-2018 IPR000160 GGDEF domain CLOST_0126 83d893e0817825149819b0064ebd0322 688 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 490 639 6.0E-32 T 13-10-2018 IPR000160 GGDEF domain CLOST_0126 83d893e0817825149819b0064ebd0322 688 Gene3D G3DSA:3.30.70.270 482 643 2.0E-38 T 13-10-2018 CLOST_0126 83d893e0817825149819b0064ebd0322 688 SMART SM00086 441 483 0.0081 T 13-10-2018 IPR001610 PAC motif CLOST_0126 83d893e0817825149819b0064ebd0322 688 SMART SM00086 153 193 320.0 T 13-10-2018 IPR001610 PAC motif CLOST_0375 2a01dc439eac6c82e80e58b082dcb611 340 Gene3D G3DSA:3.40.50.2300 144 334 1.9E-95 T 13-10-2018 CLOST_0375 2a01dc439eac6c82e80e58b082dcb611 340 SUPERFAMILY SSF53822 43 252 1.45E-12 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_0375 2a01dc439eac6c82e80e58b082dcb611 340 Gene3D G3DSA:3.40.50.2300 49 297 1.9E-95 T 13-10-2018 CLOST_0375 2a01dc439eac6c82e80e58b082dcb611 340 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 42 338 8.9E-73 T 13-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CLOST_0441 f75db9f2440c7067942de0e3da7ac0f1 200 TIGRFAM TIGR02646 TIGR02646: TIGR02646 family protein 24 165 1.3E-19 T 13-10-2018 IPR013467 Conserved hypothetical protein CHP02646 CLOST_0441 f75db9f2440c7067942de0e3da7ac0f1 200 Gene3D G3DSA:3.30.40.60 15 122 4.9E-5 T 13-10-2018 CLOST_0441 f75db9f2440c7067942de0e3da7ac0f1 200 Pfam PF01844 HNH endonuclease 53 96 3.0E-5 T 13-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CLOST_2469 84b2ff9702c2ffdcb1342a2197a9cca8 218 SUPERFAMILY SSF141571 39 216 4.58E-40 T 13-10-2018 CLOST_2469 84b2ff9702c2ffdcb1342a2197a9cca8 218 Pfam PF00805 Pentapeptide repeats (8 copies) 75 110 5.3E-9 T 13-10-2018 IPR001646 Pentapeptide repeat CLOST_2469 84b2ff9702c2ffdcb1342a2197a9cca8 218 Gene3D G3DSA:2.160.20.100 3 217 1.5E-50 T 13-10-2018 CLOST_2469 84b2ff9702c2ffdcb1342a2197a9cca8 218 Pfam PF13599 Pentapeptide repeats (9 copies) 133 197 3.7E-9 T 13-10-2018 IPR001646 Pentapeptide repeat CLOST_0749 f7bf2d6d045230eeb9ecb5e8bab05002 395 PIRSF PIRSF005243 1 395 2.8E-146 T 13-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 CLOST_0749 f7bf2d6d045230eeb9ecb5e8bab05002 395 Gene3D G3DSA:3.60.15.10 2 245 6.2E-100 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_0749 f7bf2d6d045230eeb9ecb5e8bab05002 395 Pfam PF00753 Metallo-beta-lactamase superfamily 35 170 5.9E-12 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0749 f7bf2d6d045230eeb9ecb5e8bab05002 395 Pfam PF00258 Flavodoxin 255 386 2.6E-11 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CLOST_0749 f7bf2d6d045230eeb9ecb5e8bab05002 395 Gene3D G3DSA:3.40.50.360 252 395 6.5E-37 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0749 f7bf2d6d045230eeb9ecb5e8bab05002 395 SUPERFAMILY SSF52218 250 394 1.84E-34 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0749 f7bf2d6d045230eeb9ecb5e8bab05002 395 SUPERFAMILY SSF56281 8 284 2.17E-53 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_0749 f7bf2d6d045230eeb9ecb5e8bab05002 395 SMART SM00849 34 226 5.7E-25 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 Gene3D G3DSA:3.90.1170.30 331 421 1.2E-144 T 13-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 SMART SM00941 345 419 2.0E-22 T 13-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 SUPERFAMILY SSF52418 70 329 3.79E-90 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 PIRSF PIRSF000478 1 433 1.1E-159 T 13-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 1.1E-40 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 5.8E-20 T 13-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 5.7E-19 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 SUPERFAMILY SSF54680 331 433 9.68E-25 T 13-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 Gene3D G3DSA:3.40.1030.10 77 330 1.2E-144 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 418 1.3E-170 T 13-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 13-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 Gene3D G3DSA:1.20.970.10 1 67 3.0E-26 T 13-10-2018 CLOST_1332 8ce1c19c6b6084c0baab717163fd3a9f 441 SUPERFAMILY SSF47648 1 69 1.01E-19 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1805 dd402673240fe707d82b8cd2e2b822ef 353 Gene3D G3DSA:1.20.272.10 217 349 1.0E-27 T 13-10-2018 CLOST_1805 dd402673240fe707d82b8cd2e2b822ef 353 SUPERFAMILY SSF52540 2 216 1.38E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1805 dd402673240fe707d82b8cd2e2b822ef 353 SUPERFAMILY SSF48019 221 340 1.34E-16 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CLOST_1805 dd402673240fe707d82b8cd2e2b822ef 353 Gene3D G3DSA:3.40.50.300 4 139 1.5E-33 T 13-10-2018 CLOST_1805 dd402673240fe707d82b8cd2e2b822ef 353 Pfam PF06144 DNA polymerase III, delta subunit 18 194 3.3E-27 T 13-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CLOST_1805 dd402673240fe707d82b8cd2e2b822ef 353 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 340 1.8E-52 T 13-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 SMART SM00924 26 128 1.8E-19 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 Pfam PF03448 MgtE intracellular N domain 26 126 2.3E-16 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 Pfam PF01769 Divalent cation transporter 312 433 5.0E-30 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 Gene3D G3DSA:3.10.580.10 124 252 1.8E-43 T 13-10-2018 CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 Gene3D G3DSA:1.10.357.20 265 441 1.7E-54 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 Pfam PF00571 CBS domain 192 246 9.2E-10 T 13-10-2018 IPR000644 CBS domain CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 Pfam PF00571 CBS domain 129 184 1.4E-4 T 13-10-2018 IPR000644 CBS domain CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 SUPERFAMILY SSF161093 270 440 4.84E-52 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 SUPERFAMILY SSF54631 128 264 1.52E-31 T 13-10-2018 CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 Gene3D G3DSA:1.25.60.10 2 123 5.3E-17 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 SUPERFAMILY SSF158791 4 125 2.09E-20 T 13-10-2018 CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 SMART SM00116 199 247 1.6E-4 T 13-10-2018 IPR000644 CBS domain CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 SMART SM00116 135 188 1.6 T 13-10-2018 IPR000644 CBS domain CLOST_0124 f6d4ecef31ff40bdf7014886d9918eb9 444 TIGRFAM TIGR00400 mgtE: magnesium transporter 8 441 1.5E-109 T 13-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CLOST_0896 3e17c920577a7693a6f14b79b390fb63 316 SUPERFAMILY SSF51412 3 306 1.68E-76 T 13-10-2018 CLOST_0896 3e17c920577a7693a6f14b79b390fb63 316 Pfam PF03060 Nitronate monooxygenase 77 300 4.7E-56 T 13-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CLOST_0896 3e17c920577a7693a6f14b79b390fb63 316 Gene3D G3DSA:3.20.20.70 2 313 1.4E-112 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0896 3e17c920577a7693a6f14b79b390fb63 316 TIGRFAM TIGR03151 enACPred_II: putative enoyl-[acyl-carrier-protein] reductase II 3 305 1.0E-151 T 13-10-2018 IPR017569 Enoyl-(acyl-carrier-protein) reductase II, putative CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 Gene3D G3DSA:1.25.40.10 72 184 3.0E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SUPERFAMILY SSF47413 5 64 1.21E-12 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SUPERFAMILY SSF48452 74 222 4.55E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 Gene3D G3DSA:1.10.260.40 4 68 6.1E-17 T 13-10-2018 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 Gene3D G3DSA:1.25.40.10 194 321 1.5E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00028 75 108 220.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00028 277 310 5.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00028 237 270 3.4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00028 316 349 120.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00028 197 230 120.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00028 356 389 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00028 115 148 130.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00028 155 188 400.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 Gene3D G3DSA:1.25.40.10 322 433 3.8E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SMART SM00530 9 63 2.2E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SUPERFAMILY SSF48452 359 428 4.74E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 SUPERFAMILY SSF48452 174 351 9.48E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 Pfam PF13181 Tetratricopeptide repeat 199 229 0.0036 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 Pfam PF13181 Tetratricopeptide repeat 277 304 0.071 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2577 31cebc1deca3978b2e550853d33ca217 433 Pfam PF12844 Helix-turn-helix domain 7 65 5.1E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1395 2c148963bf7476ce696de0939debcf2d 228 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 177 182 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CLOST_1395 2c148963bf7476ce696de0939debcf2d 228 TIGRFAM TIGR00608 radc: DNA repair protein RadC 15 227 6.2E-72 T 13-10-2018 IPR001405 Uncharacterised protein family UPF0758 CLOST_1395 2c148963bf7476ce696de0939debcf2d 228 SUPERFAMILY SSF47781 49 95 6.39E-7 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_1395 2c148963bf7476ce696de0939debcf2d 228 Gene3D G3DSA:3.40.140.10 103 228 2.9E-47 T 13-10-2018 CLOST_1395 2c148963bf7476ce696de0939debcf2d 228 Pfam PF04002 RadC-like JAB domain 107 226 2.8E-46 T 13-10-2018 IPR025657 RadC-like JAB domain CLOST_1799 884aec2b7a5f7f7f5ef86df4957fbe3c 265 SUPERFAMILY SSF54675 2 97 2.63E-25 T 13-10-2018 CLOST_1799 884aec2b7a5f7f7f5ef86df4957fbe3c 265 Gene3D G3DSA:3.90.1170.20 2 262 5.4E-99 T 13-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 CLOST_1799 884aec2b7a5f7f7f5ef86df4957fbe3c 265 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 8 96 2.4E-25 T 13-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CLOST_1799 884aec2b7a5f7f7f5ef86df4957fbe3c 265 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 98 263 1.0E-54 T 13-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 CLOST_1799 884aec2b7a5f7f7f5ef86df4957fbe3c 265 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 2 264 4.6E-96 T 13-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CLOST_1799 884aec2b7a5f7f7f5ef86df4957fbe3c 265 PIRSF PIRSF006250 1 265 1.6E-87 T 13-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CLOST_1799 884aec2b7a5f7f7f5ef86df4957fbe3c 265 SUPERFAMILY SSF51690 98 264 4.32E-51 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CLOST_1799 884aec2b7a5f7f7f5ef86df4957fbe3c 265 Gene3D G3DSA:3.20.20.70 112 254 5.4E-99 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 182 5.8E-4 T 13-10-2018 CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 Gene3D G3DSA:3.40.50.720 2 243 5.4E-84 T 13-10-2018 CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 5 242 1.2E-99 T 13-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 241 4.5E-68 T 13-10-2018 CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 SUPERFAMILY SSF51735 3 243 1.2E-85 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 8.4E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 8.4E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.4E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 8.4E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 8.4E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 8.4E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.5E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.5E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0898 bfdb53e57d6eb3bdf77a4f7e0bed569d 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.5E-16 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0511 f73ef1644d4effb1817a1fd95e8cf13c 272 Gene3D G3DSA:3.20.20.370 22 269 2.2E-11 T 13-10-2018 CLOST_0511 f73ef1644d4effb1817a1fd95e8cf13c 272 SUPERFAMILY SSF88713 46 239 1.67E-5 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 425 7.0E-21 T 13-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 Pfam PF09269 Domain of unknown function (DUF1967) 359 424 2.5E-23 T 13-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.4E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.4E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.4E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.4E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 SUPERFAMILY SSF82051 1 157 4.84E-54 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 SUPERFAMILY SSF102741 359 426 4.58E-19 T 13-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 13-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 Gene3D G3DSA:3.40.50.300 158 343 3.6E-57 T 13-10-2018 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 Hamap MF_01454 GTPase Obg [obg]. 1 330 47.818 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 Pfam PF01018 GTP1/OBG 3 156 1.5E-57 T 13-10-2018 IPR006169 GTP1/OBG domain CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 Gene3D G3DSA:2.40.240.60 356 426 2.1E-20 T 13-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 SUPERFAMILY SSF52540 160 333 6.13E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 Gene3D G3DSA:2.70.210.12 1 157 2.1E-56 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 Pfam PF01926 50S ribosome-binding GTPase 160 283 6.3E-25 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 PIRSF PIRSF002401 1 374 3.0E-138 T 13-10-2018 IPR035101 GTP-binding protein, Obg-type CLOST_1371 1891e7a741f4d5c201e463da46345ecd 426 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 329 3.4E-138 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CLOST_2247 b5c313e06203f3925918c38ff652e2f3 233 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 226 1.2E-66 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CLOST_2247 b5c313e06203f3925918c38ff652e2f3 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 227 1.6E-63 T 13-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CLOST_2247 b5c313e06203f3925918c38ff652e2f3 233 Gene3D G3DSA:3.90.550.10 1 233 3.1E-73 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_2247 b5c313e06203f3925918c38ff652e2f3 233 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 226 38.984 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CLOST_2247 b5c313e06203f3925918c38ff652e2f3 233 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 101 108 - T 13-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CLOST_2247 b5c313e06203f3925918c38ff652e2f3 233 SUPERFAMILY SSF53448 1 226 1.67E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0920 7c7aa2384b8385b830353025652c3054 264 SUPERFAMILY SSF81301 5 201 1.26E-55 T 13-10-2018 CLOST_0920 7c7aa2384b8385b830353025652c3054 264 Gene3D G3DSA:1.10.287.860 149 211 8.3E-24 T 13-10-2018 CLOST_0920 7c7aa2384b8385b830353025652c3054 264 Gene3D G3DSA:3.30.460.10 1 148 7.1E-48 T 13-10-2018 CLOST_0920 7c7aa2384b8385b830353025652c3054 264 SMART SM00954 45 166 3.5E-36 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 CLOST_0920 7c7aa2384b8385b830353025652c3054 264 Pfam PF04607 Region found in RelA / SpoT proteins 45 164 2.2E-35 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 Gene3D G3DSA:3.40.50.40 211 323 1.0E-34 T 13-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 Pfam PF00710 Asparaginase, N-terminal 4 192 4.1E-51 T 13-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 PIRSF PIRSF001220 1 325 6.4E-93 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 SUPERFAMILY SSF53774 2 323 1.83E-99 T 13-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 PIRSF PIRSF500176 1 325 1.1E-84 T 13-10-2018 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 Gene3D G3DSA:3.40.50.1170 2 210 7.8E-64 T 13-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 SMART SM00870 4 319 5.4E-131 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 PRINTS PR00139 Asparaginase/glutaminase family signature 254 272 2.9E-17 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 PRINTS PR00139 Asparaginase/glutaminase family signature 5 16 2.9E-17 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 PRINTS PR00139 Asparaginase/glutaminase family signature 82 100 2.9E-17 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CLOST_1447 f0376e8ddf72fcaca7cf9f3cc741f44f 325 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 7 15 - T 13-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CLOST_0049 4571874b6fc205f5a36dbdd295044036 297 SUPERFAMILY SSF82861 43 128 8.37E-18 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CLOST_0049 4571874b6fc205f5a36dbdd295044036 297 Pfam PF00924 Mechanosensitive ion channel 87 284 7.2E-52 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CLOST_0049 4571874b6fc205f5a36dbdd295044036 297 SUPERFAMILY SSF50182 130 195 1.5E-17 T 13-10-2018 IPR010920 LSM domain superfamily CLOST_0049 4571874b6fc205f5a36dbdd295044036 297 Gene3D G3DSA:2.30.30.60 145 194 2.5E-21 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily CLOST_0049 4571874b6fc205f5a36dbdd295044036 297 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 159 193 - T 13-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 CLOST_0049 4571874b6fc205f5a36dbdd295044036 297 Pfam PF05552 Conserved TM helix 38 79 4.0E-10 T 13-10-2018 IPR008910 Conserved TM helix CLOST_0049 4571874b6fc205f5a36dbdd295044036 297 SUPERFAMILY SSF82689 201 295 5.75E-26 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CLOST_0049 4571874b6fc205f5a36dbdd295044036 297 Gene3D G3DSA:3.30.70.100 198 288 3.0E-23 T 13-10-2018 CLOST_0103 f78b178ea46abec7e33edf9ea69da2f5 157 SUPERFAMILY SSF53927 2 130 8.5E-45 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CLOST_0103 f78b178ea46abec7e33edf9ea69da2f5 157 Pfam PF14437 MafB19-like deaminase 2 147 5.6E-32 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CLOST_0103 f78b178ea46abec7e33edf9ea69da2f5 157 Gene3D G3DSA:3.40.140.10 1 157 4.7E-50 T 13-10-2018 CLOST_0103 f78b178ea46abec7e33edf9ea69da2f5 157 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CLOST_0103 f78b178ea46abec7e33edf9ea69da2f5 157 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 147 37.569 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CLOST_2071 7dcdde9c95be2502a83f8b33d643d206 289 Pfam PF00583 Acetyltransferase (GNAT) family 176 274 2.2E-14 T 13-10-2018 IPR000182 GNAT domain CLOST_2071 7dcdde9c95be2502a83f8b33d643d206 289 Gene3D G3DSA:3.40.630.30 12 123 4.7E-8 T 13-10-2018 CLOST_2071 7dcdde9c95be2502a83f8b33d643d206 289 SUPERFAMILY SSF55729 19 113 7.74E-9 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2071 7dcdde9c95be2502a83f8b33d643d206 289 SUPERFAMILY SSF55729 123 284 6.15E-24 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2071 7dcdde9c95be2502a83f8b33d643d206 289 Gene3D G3DSA:3.40.630.30 124 287 5.1E-25 T 13-10-2018 CLOST_1973 8222c249636f9090135f0bfc0c713008 577 SUPERFAMILY SSF48452 81 200 6.33E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1973 8222c249636f9090135f0bfc0c713008 577 Pfam PF00563 EAL domain 329 563 2.0E-61 T 13-10-2018 IPR001633 EAL domain CLOST_1973 8222c249636f9090135f0bfc0c713008 577 SUPERFAMILY SSF141868 329 574 7.19E-73 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_1973 8222c249636f9090135f0bfc0c713008 577 Gene3D G3DSA:1.25.40.10 46 280 2.8E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1973 8222c249636f9090135f0bfc0c713008 577 Gene3D G3DSA:3.20.20.450 326 576 1.2E-73 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_1973 8222c249636f9090135f0bfc0c713008 577 SMART SM00028 114 147 0.83 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1973 8222c249636f9090135f0bfc0c713008 577 SMART SM00028 154 187 3.2 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1973 8222c249636f9090135f0bfc0c713008 577 SMART SM00052 323 568 9.2E-69 T 13-10-2018 IPR001633 EAL domain CLOST_0994 b305ef33fda3dbe8993a1cca74ec071a 241 SUPERFAMILY SSF53790 2 239 2.36E-53 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 CLOST_0994 b305ef33fda3dbe8993a1cca74ec071a 241 Gene3D G3DSA:3.40.1010.10 1 110 1.0E-31 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 CLOST_0994 b305ef33fda3dbe8993a1cca74ec071a 241 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 2 240 1.5E-101 T 13-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CLOST_0994 b305ef33fda3dbe8993a1cca74ec071a 241 Gene3D G3DSA:3.30.950.10 111 241 8.4E-52 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 CLOST_0994 b305ef33fda3dbe8993a1cca74ec071a 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 3.9E-36 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 CLOST_2431 bf4c2ba05acf8bf87926f57b63a8620e 218 Gene3D G3DSA:3.90.1490.10 141 217 2.1E-12 T 13-10-2018 CLOST_2431 bf4c2ba05acf8bf87926f57b63a8620e 218 Gene3D G3DSA:3.40.50.620 1 140 3.4E-32 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_2431 bf4c2ba05acf8bf87926f57b63a8620e 218 Pfam PF01902 Diphthamide synthase 7 207 1.1E-40 T 13-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CLOST_2431 bf4c2ba05acf8bf87926f57b63a8620e 218 PIRSF PIRSF039123 2 218 3.4E-62 T 13-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CLOST_2431 bf4c2ba05acf8bf87926f57b63a8620e 218 SUPERFAMILY SSF52402 2 203 1.23E-56 T 13-10-2018 CLOST_2431 bf4c2ba05acf8bf87926f57b63a8620e 218 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 7 209 5.6E-40 T 13-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CLOST_0571 5774760e9ba6551a99dcee942c07a627 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 4.8E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0571 5774760e9ba6551a99dcee942c07a627 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 4.8E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0571 5774760e9ba6551a99dcee942c07a627 94 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 4.8E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0571 5774760e9ba6551a99dcee942c07a627 94 Gene3D G3DSA:1.10.10.10 2 94 4.7E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0571 5774760e9ba6551a99dcee942c07a627 94 SMART SM00418 16 91 5.2E-19 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0571 5774760e9ba6551a99dcee942c07a627 94 SUPERFAMILY SSF46785 4 93 3.96E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0571 5774760e9ba6551a99dcee942c07a627 94 Pfam PF12840 Helix-turn-helix domain 16 74 9.0E-14 T 13-10-2018 CLOST_2162 058f7fdda387b1dc1774ff9c4b3ff3dc 142 Pfam PF00572 Ribosomal protein L13 14 136 4.9E-54 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CLOST_2162 058f7fdda387b1dc1774ff9c4b3ff3dc 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 13-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CLOST_2162 058f7fdda387b1dc1774ff9c4b3ff3dc 142 PIRSF PIRSF002181 1 141 5.7E-50 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CLOST_2162 058f7fdda387b1dc1774ff9c4b3ff3dc 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 27.694 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CLOST_2162 058f7fdda387b1dc1774ff9c4b3ff3dc 142 SUPERFAMILY SSF52161 1 138 1.57E-54 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2162 058f7fdda387b1dc1774ff9c4b3ff3dc 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 141 5.2E-59 T 13-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2162 058f7fdda387b1dc1774ff9c4b3ff3dc 142 Gene3D G3DSA:3.90.1180.10 1 142 1.0E-60 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_0801 fff3161ea8045c45bf229e0789372026 230 SUPERFAMILY SSF56014 86 218 3.4E-30 T 13-10-2018 CLOST_0801 fff3161ea8045c45bf229e0789372026 230 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 12 74 3.1E-14 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_0801 fff3161ea8045c45bf229e0789372026 230 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 107 223 4.4E-17 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_0801 fff3161ea8045c45bf229e0789372026 230 Gene3D G3DSA:3.30.413.10 77 229 2.5E-27 T 13-10-2018 CLOST_0801 fff3161ea8045c45bf229e0789372026 230 PIRSF PIRSF037487 9 218 5.0E-65 T 13-10-2018 IPR017220 Sulphite reductase, assimilatory CLOST_0801 fff3161ea8045c45bf229e0789372026 230 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 129 145 - T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_0801 fff3161ea8045c45bf229e0789372026 230 SUPERFAMILY SSF55124 16 74 1.64E-13 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_0694 509530d5d8f55a688b13310fba69c34e 351 SUPERFAMILY SSF103481 199 292 1.96E-12 T 13-10-2018 CLOST_0694 509530d5d8f55a688b13310fba69c34e 351 SUPERFAMILY SSF103481 70 148 1.44E-8 T 13-10-2018 CLOST_0694 509530d5d8f55a688b13310fba69c34e 351 Pfam PF00892 EamA-like transporter family 9 146 2.8E-16 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_0694 509530d5d8f55a688b13310fba69c34e 351 Pfam PF00892 EamA-like transporter family 158 288 3.7E-12 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 SMART SM00382 26 231 1.8E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 SMART SM00382 354 517 2.1E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 ProSitePatterns PS00211 ABC transporters family signature. 444 458 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 Pfam PF12848 ABC transporter 225 308 2.0E-8 T 13-10-2018 IPR032781 ABC-transporter extension domain CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 Pfam PF00005 ABC transporter 345 472 1.5E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 SUPERFAMILY SSF52540 327 520 8.13E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 Pfam PF00005 ABC transporter 18 184 2.1E-18 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 SUPERFAMILY SSF52540 2 240 2.27E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 Gene3D G3DSA:3.40.50.300 1 278 6.6E-45 T 13-10-2018 CLOST_0097 3989f6937a908e5bdb050bf22d9b2e01 578 Gene3D G3DSA:3.40.50.300 311 553 1.9E-46 T 13-10-2018 CLOST_1568 a57b47a581394dc463ae45ceda05dfd3 541 Pfam PF07508 Recombinase 183 293 2.0E-16 T 13-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CLOST_1568 a57b47a581394dc463ae45ceda05dfd3 541 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CLOST_1568 a57b47a581394dc463ae45ceda05dfd3 541 Pfam PF00239 Resolvase, N terminal domain 3 152 2.4E-36 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOST_1568 a57b47a581394dc463ae45ceda05dfd3 541 SMART SM00857 3 152 8.2E-51 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOST_1568 a57b47a581394dc463ae45ceda05dfd3 541 SUPERFAMILY SSF53041 1 152 1.57E-36 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 CLOST_1568 a57b47a581394dc463ae45ceda05dfd3 541 Pfam PF13408 Recombinase zinc beta ribbon domain 306 367 2.7E-10 T 13-10-2018 IPR025827 Recombinase zinc beta ribbon domain CLOST_1568 a57b47a581394dc463ae45ceda05dfd3 541 Gene3D G3DSA:3.40.50.1390 1 135 3.2E-38 T 13-10-2018 CLOST_1568 a57b47a581394dc463ae45ceda05dfd3 541 Gene3D G3DSA:1.10.10.2600 136 294 3.4E-12 T 13-10-2018 IPR038109 DNA-binding recombinase domain superfamily CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Gene3D G3DSA:3.40.50.10190 581 667 3.9E-22 T 13-10-2018 IPR036420 BRCT domain superfamily CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SUPERFAMILY SSF56091 9 317 1.66E-115 T 13-10-2018 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 11 317 4.2E-121 T 13-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 17 660 3.8E-248 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Gene3D G3DSA:1.10.150.20 503 580 3.2E-25 T 13-10-2018 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Gene3D G3DSA:1.10.287.610 5 76 6.9E-28 T 13-10-2018 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Gene3D G3DSA:2.40.50.140 317 389 1.4E-29 T 13-10-2018 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Hamap MF_01588 DNA ligase [ligA]. 8 665 48.753 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 118 147 - T 13-10-2018 IPR018239 NAD-dependent DNA ligase, active site CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SMART SM00278 478 497 93.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SMART SM00278 542 561 0.014 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SMART SM00278 444 463 380.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Pfam PF12826 Helix-hairpin-helix motif 508 571 9.7E-23 T 13-10-2018 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SUPERFAMILY SSF50249 317 396 1.58E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SMART SM00292 591 668 7.2E-13 T 13-10-2018 IPR001357 BRCT domain CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 PIRSF PIRSF001604 1 670 4.3E-247 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 591 665 2.1E-11 T 13-10-2018 IPR001357 BRCT domain CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Gene3D G3DSA:2.20.70.80 391 428 1.1E-8 T 13-10-2018 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 330 345 - T 13-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SUPERFAMILY SSF52113 591 667 3.55E-14 T 13-10-2018 IPR036420 BRCT domain superfamily CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 406 432 1.9E-8 T 13-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SUPERFAMILY SSF47781 403 581 1.59E-59 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 321 396 1.6E-32 T 13-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 SMART SM00532 9 446 6.4E-252 T 13-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Gene3D G3DSA:1.10.150.20 430 502 2.4E-27 T 13-10-2018 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Gene3D G3DSA:3.30.470.90 77 316 4.2E-95 T 13-10-2018 CLOST_0579 3d0f353fb9ef4465db7756ee78167497 683 Pfam PF14520 Helix-hairpin-helix domain 444 497 1.5E-5 T 13-10-2018 CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 PIRSF PIRSF000521 156 400 1.6E-38 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 PIRSF PIRSF000521 4 165 4.0E-6 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 SUPERFAMILY SSF53383 17 399 7.79E-126 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 Gene3D G3DSA:3.40.640.10 61 306 1.2E-145 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 Pfam PF00202 Aminotransferase class-III 22 396 3.1E-121 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 224 261 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 17 400 67.872 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 Gene3D G3DSA:3.90.1150.10 26 390 1.2E-145 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0136 ee79fb94d4f71503c4611d46ccaf333f 404 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 17 397 3.0E-149 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CLOST_2103 e20f7717bfe8ce104a5d4589873111a0 1138 SUPERFAMILY SSF56524 382 502 6.8E-7 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 CLOST_2103 e20f7717bfe8ce104a5d4589873111a0 1138 Pfam PF07494 Two component regulator propeller 813 835 8.6E-5 T 13-10-2018 IPR011110 Two component regulator propeller CLOST_2103 e20f7717bfe8ce104a5d4589873111a0 1138 SUPERFAMILY SSF63829 816 1037 6.05E-11 T 13-10-2018 CLOST_2103 e20f7717bfe8ce104a5d4589873111a0 1138 Gene3D G3DSA:2.130.10.10 979 1136 8.7E-9 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 CLOST_2103 e20f7717bfe8ce104a5d4589873111a0 1138 Gene3D G3DSA:2.130.10.10 777 978 4.6E-24 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 CLOST_2571 9866c92e4ddf7ce14052f5432e3bd5f8 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 6.0E-28 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2571 9866c92e4ddf7ce14052f5432e3bd5f8 95 Pfam PF01250 Ribosomal protein S6 3 91 3.5E-30 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2571 9866c92e4ddf7ce14052f5432e3bd5f8 95 SUPERFAMILY SSF54995 1 94 7.06E-32 T 13-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2571 9866c92e4ddf7ce14052f5432e3bd5f8 95 Gene3D G3DSA:3.30.70.60 1 95 9.6E-34 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CLOST_2571 9866c92e4ddf7ce14052f5432e3bd5f8 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 22.102 T 13-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOST_2156 fdc6ac90a29c8be03f181498c16ad202 67 SUPERFAMILY SSF47598 5 53 1.17E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 CLOST_2156 fdc6ac90a29c8be03f181498c16ad202 67 Gene3D G3DSA:1.10.1220.10 1 51 2.0E-7 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CLOST_2031 0fde06d78467d1c37dfa73c29a387c61 227 SUPERFAMILY SSF46785 148 223 3.29E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2031 0fde06d78467d1c37dfa73c29a387c61 227 Pfam PF00027 Cyclic nucleotide-binding domain 31 115 9.8E-8 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_2031 0fde06d78467d1c37dfa73c29a387c61 227 SUPERFAMILY SSF51206 12 142 7.86E-22 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like CLOST_2031 0fde06d78467d1c37dfa73c29a387c61 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 173 189 2.9E-6 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_2031 0fde06d78467d1c37dfa73c29a387c61 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 189 204 2.9E-6 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_2031 0fde06d78467d1c37dfa73c29a387c61 227 Gene3D G3DSA:2.60.120.1460 16 223 2.5E-46 T 13-10-2018 CLOST_2031 0fde06d78467d1c37dfa73c29a387c61 227 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 7.5E-18 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_2031 0fde06d78467d1c37dfa73c29a387c61 227 SMART SM00419 167 215 2.0E-11 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_0287 84af495b2419385d6688f9d2d025ae4e 249 SMART SM01001 120 249 5.3E-35 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CLOST_0287 84af495b2419385d6688f9d2d025ae4e 249 Gene3D G3DSA:3.40.50.7700 122 249 2.3E-34 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 CLOST_0287 84af495b2419385d6688f9d2d025ae4e 249 Pfam PF00731 AIR carboxylase 122 246 8.9E-16 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CLOST_0287 84af495b2419385d6688f9d2d025ae4e 249 SUPERFAMILY SSF52255 121 248 1.83E-29 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 Pfam PF07694 5TMR of 5TMR-LYT 26 191 5.6E-41 T 13-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 SUPERFAMILY SSF55874 415 552 5.37E-14 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 Pfam PF06580 Histidine kinase 361 439 9.7E-27 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 Gene3D G3DSA:1.10.1760.20 41 196 3.3E-7 T 13-10-2018 CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 SMART SM00387 453 556 1.8E-5 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 Gene3D G3DSA:3.30.565.10 414 558 1.1E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 SUPERFAMILY SSF55781 223 348 9.32E-6 T 13-10-2018 CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 Pfam PF13185 GAF domain 223 342 9.3E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 Gene3D G3DSA:3.30.450.40 197 350 7.8E-6 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_1078 bf8c15ee4fafe582ca2563bb4ea0d0b7 559 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 457 555 3.9E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1532 c48b8a799a9dc36cc43d9f4deec8ef28 293 Pfam PF03592 Terminase small subunit 77 250 1.6E-43 T 13-10-2018 IPR005335 Terminase small subunit GO:0006323 CLOST_1532 c48b8a799a9dc36cc43d9f4deec8ef28 293 Pfam PF06056 Putative ATPase subunit of terminase (gpP-like) 18 48 2.2E-4 T 13-10-2018 IPR010332 ATPase terminase subunit, putative GO:0005524|GO:0019069 CLOST_1532 c48b8a799a9dc36cc43d9f4deec8ef28 293 Gene3D G3DSA:1.10.10.1400 73 135 4.8E-17 T 13-10-2018 IPR038713 Terminase small subunit, N-terminal domain superfamily CLOST_2252 a61747302cfcb9ebba7a5983396b17aa 309 Gene3D G3DSA:1.10.3720.10 74 303 4.2E-23 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2252 a61747302cfcb9ebba7a5983396b17aa 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 307 4.4E-38 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_2252 a61747302cfcb9ebba7a5983396b17aa 309 SUPERFAMILY SSF161098 80 295 1.7E-18 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1796 46358f8332cf3c05b5b607a3e45f2170 386 SUPERFAMILY SSF102114 7 385 1.44E-110 T 13-10-2018 CLOST_1796 46358f8332cf3c05b5b607a3e45f2170 386 Pfam PF04055 Radical SAM superfamily 14 184 2.5E-20 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1796 46358f8332cf3c05b5b607a3e45f2170 386 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 9 363 1.0E-92 T 13-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 CLOST_1796 46358f8332cf3c05b5b607a3e45f2170 386 Gene3D G3DSA:3.80.30.20 1 309 9.4E-104 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1796 46358f8332cf3c05b5b607a3e45f2170 386 Pfam PF06969 HemN C-terminal domain 315 374 1.8E-13 T 13-10-2018 IPR010723 HemN, C-terminal CLOST_1796 46358f8332cf3c05b5b607a3e45f2170 386 SMART SM00729 8 231 1.8E-54 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 288 2.6E-151 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 57.21 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 280 2.2E-148 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 Gene3D G3DSA:1.20.58.180 205 285 4.2E-35 T 13-10-2018 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 3.5E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 3.5E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 3.5E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 3.5E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 3.5E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 3.5E-63 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 Gene3D G3DSA:3.30.930.10 1 204 2.7E-108 T 13-10-2018 CLOST_1771 62ea7f28f3ec97d348c3a9ba217e5f98 294 SUPERFAMILY SSF55681 1 280 3.73E-131 T 13-10-2018 CLOST_2188 364bb0bada8a32dfcd7140d0fc4e14d4 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 8.1E-55 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CLOST_2188 364bb0bada8a32dfcd7140d0fc4e14d4 122 Gene3D G3DSA:2.40.150.20 1 122 2.1E-53 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2188 364bb0bada8a32dfcd7140d0fc4e14d4 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.0E-56 T 13-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CLOST_2188 364bb0bada8a32dfcd7140d0fc4e14d4 122 SMART SM01374 1 122 2.9E-86 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CLOST_2188 364bb0bada8a32dfcd7140d0fc4e14d4 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.21 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CLOST_2188 364bb0bada8a32dfcd7140d0fc4e14d4 122 SUPERFAMILY SSF50193 1 122 4.32E-51 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2188 364bb0bada8a32dfcd7140d0fc4e14d4 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 13-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 Gene3D G3DSA:3.30.70.270 332 506 1.4E-43 T 13-10-2018 CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 Pfam PF03924 CHASE domain 105 190 3.5E-9 T 13-10-2018 IPR006189 CHASE domain CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 SMART SM01079 42 215 7.6E-14 T 13-10-2018 IPR006189 CHASE domain CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 SUPERFAMILY SSF141868 510 753 1.57E-77 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 SUPERFAMILY SSF55073 342 497 9.42E-41 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 335 494 9.9E-36 T 13-10-2018 IPR000160 GGDEF domain CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 Pfam PF00563 EAL domain 511 742 1.3E-63 T 13-10-2018 IPR001633 EAL domain CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 Pfam PF00990 Diguanylate cyclase, GGDEF domain 338 491 4.9E-36 T 13-10-2018 IPR000160 GGDEF domain CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 SMART SM00267 326 495 8.5E-39 T 13-10-2018 IPR000160 GGDEF domain CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 SMART SM00052 505 747 9.6E-93 T 13-10-2018 IPR001633 EAL domain CLOST_0665 dd9909ba02f8535562cad57eb1d22730 759 Gene3D G3DSA:3.20.20.450 507 756 4.0E-82 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0649 9333161e8920a57f2c9aed9fc05de4f1 339 Pfam PF00793 DAHP synthetase I family 89 329 7.5E-75 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CLOST_0649 9333161e8920a57f2c9aed9fc05de4f1 339 Gene3D G3DSA:3.30.70.1140 1 76 4.5E-24 T 13-10-2018 CLOST_0649 9333161e8920a57f2c9aed9fc05de4f1 339 Gene3D G3DSA:3.20.20.70 77 332 5.0E-102 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0649 9333161e8920a57f2c9aed9fc05de4f1 339 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 73 327 8.9E-119 T 13-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CLOST_0649 9333161e8920a57f2c9aed9fc05de4f1 339 SUPERFAMILY SSF51569 1 332 4.58E-114 T 13-10-2018 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 SMART SM00363 98 161 4.4E-18 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 6.3E-71 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 Gene3D G3DSA:3.10.290.10 97 192 1.5E-83 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 33.468 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 Gene3D G3DSA:1.10.1050.10 6 207 1.5E-83 T 13-10-2018 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 4.7E-32 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 96 120 - T 13-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 SMART SM01390 3 97 2.1E-54 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 Pfam PF01479 S4 domain 98 145 1.1E-17 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2171 854973837ae9e6e47e81bb69c5350169 207 SUPERFAMILY SSF55174 3 207 3.14E-63 T 13-10-2018 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 3.8E-26 T 13-10-2018 IPR013185 Translation elongation factor, KOW-like CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 Gene3D G3DSA:2.40.50.140 128 185 2.8E-28 T 13-10-2018 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 8.3E-28 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 SUPERFAMILY SSF50249 128 185 3.43E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 SMART SM00841 129 184 1.8E-34 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 13-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 Gene3D G3DSA:2.30.30.30 1 62 1.0E-26 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 50.179 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 3.1E-20 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 SUPERFAMILY SSF50104 1 62 2.61E-21 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.3E-77 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 SUPERFAMILY SSF50249 65 129 2.48E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 PIRSF PIRSF005901 1 185 2.3E-66 T 13-10-2018 IPR020599 Translation elongation factor P/YeiP CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 SMART SM01185 67 121 1.2E-23 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CLOST_1587 5ae169e0b266ed641c34f56bbbc25e89 185 Gene3D G3DSA:2.40.50.140 64 127 6.8E-25 T 13-10-2018 CLOST_1927 cffd66f062bf35cdad2328ee904e5250 165 Pfam PF02915 Rubrerythrin 6 147 1.1E-17 T 13-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CLOST_1927 cffd66f062bf35cdad2328ee904e5250 165 Gene3D G3DSA:1.20.1260.10 1 152 5.1E-27 T 13-10-2018 IPR012347 Ferritin-like CLOST_1927 cffd66f062bf35cdad2328ee904e5250 165 SUPERFAMILY SSF47240 4 155 1.75E-23 T 13-10-2018 IPR009078 Ferritin-like superfamily CLOST_0616 5b16503efc67d705daca255ba49528b1 382 SUPERFAMILY SSF53383 3 378 8.46E-96 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0616 5b16503efc67d705daca255ba49528b1 382 Pfam PF00266 Aminotransferase class-V 3 371 1.1E-90 T 13-10-2018 IPR000192 Aminotransferase class V domain CLOST_0616 5b16503efc67d705daca255ba49528b1 382 Gene3D G3DSA:3.90.1150.10 3 372 6.6E-114 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0616 5b16503efc67d705daca255ba49528b1 382 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 3 378 9.0E-142 T 13-10-2018 IPR010969 Cysteine desulfurase-related, unknown function CLOST_0616 5b16503efc67d705daca255ba49528b1 382 Gene3D G3DSA:3.40.640.10 22 273 6.6E-114 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0616 5b16503efc67d705daca255ba49528b1 382 PIRSF PIRSF005572 1 382 1.1E-51 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 CLOST_0616 5b16503efc67d705daca255ba49528b1 382 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 212 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 SUPERFAMILY SSF48452 130 206 5.06E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 Pfam PF13181 Tetratricopeptide repeat 326 357 0.0043 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 Pfam PF13181 Tetratricopeptide repeat 178 204 0.19 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 SUPERFAMILY SSF48452 232 358 5.69E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 Pfam PF13432 Tetratricopeptide repeat 232 287 9.8E-7 T 13-10-2018 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 Gene3D G3DSA:1.25.40.10 81 227 5.3E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 SMART SM00028 291 324 0.21 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 SMART SM00028 175 208 5.4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 SMART SM00028 325 358 0.56 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 SMART SM00028 257 290 0.013 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1154 19d0d6233176c8f84f2e7709e32256f2 371 Gene3D G3DSA:1.25.40.10 228 371 2.2E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 Gene3D G3DSA:1.10.260.40 1 61 2.2E-24 T 13-10-2018 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 SUPERFAMILY SSF53822 62 330 1.76E-76 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 3.0E-19 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 Gene3D G3DSA:3.40.50.2300 63 309 9.8E-80 T 13-10-2018 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.3E-7 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.3E-7 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 SUPERFAMILY SSF47413 2 61 8.26E-20 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 13-10-2018 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 Pfam PF13377 Periplasmic binding protein-like domain 170 331 5.3E-35 T 13-10-2018 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 SMART SM00354 2 72 9.1E-33 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_1934 9f8c23280fb9f9dfa149ff77822bd5f3 331 Gene3D G3DSA:3.40.50.2300 161 291 9.8E-80 T 13-10-2018 CLOST_0561 0c90f8f803b96879cd32b13aeb67418d 190 Pfam PF00717 Peptidase S24-like 48 96 8.6E-6 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CLOST_0561 0c90f8f803b96879cd32b13aeb67418d 190 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 167 7.8E-39 T 13-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CLOST_0561 0c90f8f803b96879cd32b13aeb67418d 190 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 48 63 3.8E-6 T 13-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CLOST_0561 0c90f8f803b96879cd32b13aeb67418d 190 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 107 118 3.8E-6 T 13-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CLOST_0561 0c90f8f803b96879cd32b13aeb67418d 190 SUPERFAMILY SSF51306 43 141 3.24E-9 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 326 42.23 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 SUPERFAMILY SSF48179 181 324 1.87E-61 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 181 323 1.2E-62 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 11 175 2.7E-76 T 13-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 12 324 9.4E-136 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 PIRSF PIRSF000116 199 325 5.1E-13 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 PIRSF PIRSF000116 2 203 1.6E-45 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 Gene3D G3DSA:3.40.50.720 1 179 2.4E-77 T 13-10-2018 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 Gene3D G3DSA:1.10.3730.40 180 328 7.1E-65 T 13-10-2018 CLOST_1421 ae727c08f802550e59eccb7be6da37a1 328 SUPERFAMILY SSF51735 1 180 1.82E-73 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_2383 e47237e9cb0598d39d16d009c5d4f23e 322 SMART SM00267 141 319 2.8E-38 T 13-10-2018 IPR000160 GGDEF domain CLOST_2383 e47237e9cb0598d39d16d009c5d4f23e 322 Gene3D G3DSA:3.30.70.270 147 322 1.6E-48 T 13-10-2018 CLOST_2383 e47237e9cb0598d39d16d009c5d4f23e 322 Pfam PF00990 Diguanylate cyclase, GGDEF domain 152 314 3.7E-37 T 13-10-2018 IPR000160 GGDEF domain CLOST_2383 e47237e9cb0598d39d16d009c5d4f23e 322 SUPERFAMILY SSF55073 157 320 7.45E-37 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2383 e47237e9cb0598d39d16d009c5d4f23e 322 Gene3D G3DSA:3.30.450.20 2 117 6.5E-12 T 13-10-2018 CLOST_2383 e47237e9cb0598d39d16d009c5d4f23e 322 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 150 317 1.6E-35 T 13-10-2018 IPR000160 GGDEF domain CLOST_2383 e47237e9cb0598d39d16d009c5d4f23e 322 SUPERFAMILY SSF55785 7 73 2.86E-7 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2186 37682a8686fd4e1fc5aeee3b2d7852f0 180 Pfam PF00673 ribosomal L5P family C-terminus 85 178 4.3E-41 T 13-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2186 37682a8686fd4e1fc5aeee3b2d7852f0 180 PIRSF PIRSF002161 2 180 5.1E-67 T 13-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2186 37682a8686fd4e1fc5aeee3b2d7852f0 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 13-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2186 37682a8686fd4e1fc5aeee3b2d7852f0 180 Pfam PF00281 Ribosomal protein L5 25 81 6.1E-28 T 13-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2186 37682a8686fd4e1fc5aeee3b2d7852f0 180 Gene3D G3DSA:3.30.1440.10 1 180 4.2E-81 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2186 37682a8686fd4e1fc5aeee3b2d7852f0 180 SUPERFAMILY SSF55282 4 179 3.06E-77 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2186 37682a8686fd4e1fc5aeee3b2d7852f0 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.339 T 13-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1775 7e2e729d7978175fcdd7b4d560df4956 130 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 97 3.0E-17 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CLOST_1775 7e2e729d7978175fcdd7b4d560df4956 130 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 130 4.4E-47 T 13-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CLOST_1775 7e2e729d7978175fcdd7b4d560df4956 130 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CLOST_1775 7e2e729d7978175fcdd7b4d560df4956 130 SUPERFAMILY SSF53927 5 130 5.02E-44 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CLOST_1775 7e2e729d7978175fcdd7b4d560df4956 130 Gene3D G3DSA:3.40.140.10 1 130 9.4E-53 T 13-10-2018 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 302 1.1E-86 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 SMART SM00363 17 81 1.5E-9 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 Pfam PF01479 S4 domain 18 57 2.0E-7 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 Pfam PF00849 RNA pseudouridylate synthase 90 245 5.3E-31 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 SUPERFAMILY SSF55174 16 102 4.12E-9 T 13-10-2018 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 Gene3D G3DSA:3.30.2350.10 73 292 2.5E-69 T 13-10-2018 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 Gene3D G3DSA:3.10.290.10 5 72 1.3E-17 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 137 151 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1870 331af5e9585dd29ac201125e428ae800 306 SUPERFAMILY SSF55120 77 302 2.88E-71 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_0573 c4836c1732a7ce167ed7b4afa61d1688 299 SMART SM00046 3 129 0.002 T 13-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CLOST_0573 c4836c1732a7ce167ed7b4afa61d1688 299 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 295 1.9E-51 T 13-10-2018 IPR005218 Diacylglycerol/lipid kinase CLOST_0573 c4836c1732a7ce167ed7b4afa61d1688 299 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 123 2.4E-23 T 13-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CLOST_0573 c4836c1732a7ce167ed7b4afa61d1688 299 SUPERFAMILY SSF111331 1 296 2.62E-59 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily CLOST_0573 c4836c1732a7ce167ed7b4afa61d1688 299 Gene3D G3DSA:2.60.200.40 129 288 7.7E-27 T 13-10-2018 CLOST_0573 c4836c1732a7ce167ed7b4afa61d1688 299 Gene3D G3DSA:3.40.50.10330 1 128 1.5E-28 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 Pfam PF02384 N-6 DNA Methylase 166 476 2.6E-59 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 Gene3D G3DSA:1.20.1260.30 5 83 1.2E-6 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 Gene3D G3DSA:3.40.50.150 166 478 3.2E-86 T 13-10-2018 CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 Pfam PF12161 HsdM N-terminal domain 17 150 7.0E-20 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 SUPERFAMILY SSF53335 14 586 2.5E-107 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 220 234 4.9E-8 T 13-10-2018 CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 187 203 4.9E-8 T 13-10-2018 CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 333 357 4.9E-8 T 13-10-2018 CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 292 304 4.9E-8 T 13-10-2018 CLOST_1265 ca4e86c44faea3ef8f3682b92a594cf9 597 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 295 301 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOST_0887 073597f40d6b93db3546a55c38b2c87d 331 Gene3D G3DSA:3.40.50.150 1 182 2.9E-56 T 13-10-2018 CLOST_0887 073597f40d6b93db3546a55c38b2c87d 331 SUPERFAMILY SSF50800 188 328 1.05E-18 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily CLOST_0887 073597f40d6b93db3546a55c38b2c87d 331 Gene3D G3DSA:2.40.33.20 183 330 1.5E-11 T 13-10-2018 CLOST_0887 073597f40d6b93db3546a55c38b2c87d 331 Pfam PF06962 Putative rRNA methylase 48 180 1.7E-39 T 13-10-2018 IPR010719 Putative rRNA methylase CLOST_0887 073597f40d6b93db3546a55c38b2c87d 331 SUPERFAMILY SSF53335 12 156 5.84E-22 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Hamap MF_01895 Ribonuclease R [rnr]. 32 706 56.613 T 13-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 ProSitePatterns PS01175 Ribonuclease II family signature. 544 568 - T 13-10-2018 IPR022966 Ribonuclease II/R, conserved site CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 59 703 6.7E-212 T 13-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 TIGRFAM TIGR02063 RNase_R: ribonuclease R 4 705 7.6E-262 T 13-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 SUPERFAMILY SSF50249 53 134 3.3E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Gene3D G3DSA:1.10.10.10 2 59 3.2E-5 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Pfam PF08206 Ribonuclease B OB domain 141 200 8.7E-8 T 13-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Pfam PF08206 Ribonuclease B OB domain 72 131 4.2E-16 T 13-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 SUPERFAMILY SSF50249 125 224 1.47E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 SMART SM00955 247 577 3.0E-173 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Gene3D G3DSA:2.40.50.140 136 202 1.7E-8 T 13-10-2018 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Gene3D G3DSA:2.40.50.140 60 134 2.0E-17 T 13-10-2018 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Gene3D G3DSA:2.40.50.140 627 705 1.2E-17 T 13-10-2018 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 SUPERFAMILY SSF50249 626 705 6.08E-20 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Pfam PF00575 S1 RNA binding domain 625 695 1.3E-11 T 13-10-2018 IPR003029 S1 domain GO:0003676 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 SMART SM00316 624 706 7.5E-13 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 Pfam PF00773 RNB domain 247 576 1.6E-116 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 SMART SM00357 71 132 4.3E-8 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 SMART SM00357 137 201 2.1E-4 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 CLOST_0655 e6fa4b629c6d3117bc75c8178046076e 706 SUPERFAMILY SSF50249 208 624 3.48E-146 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2294 be58307cb3f61106d627230c109cff02 1195 SUPERFAMILY SSF46548 106 210 4.81E-19 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Pfam PF00037 4Fe-4S binding domain 663 681 1.6E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Gene3D G3DSA:2.20.25.90 696 747 2.1E-11 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Gene3D G3DSA:3.30.70.20 602 684 1.4E-26 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 SUPERFAMILY SSF54862 570 683 1.67E-25 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 666 677 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 85 2.2E-18 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 202 496 3.2E-29 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Gene3D G3DSA:3.10.20.740 11 125 6.1E-36 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Gene3D G3DSA:3.40.228.10 827 992 3.6E-8 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Gene3D G3DSA:3.40.50.740 994 1140 4.1E-18 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 SUPERFAMILY SSF53706 696 1124 7.33E-74 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 SUPERFAMILY SSF51971 410 513 3.77E-6 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 107 186 2.3E-17 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 PRINTS PR00419 Adrenodoxin reductase family signature 333 347 1.6E-18 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 PRINTS PR00419 Adrenodoxin reductase family signature 267 277 1.6E-18 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 PRINTS PR00419 Adrenodoxin reductase family signature 225 238 1.6E-18 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 PRINTS PR00419 Adrenodoxin reductase family signature 202 224 1.6E-18 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Gene3D G3DSA:3.50.50.60 328 526 1.2E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Gene3D G3DSA:3.50.50.60 198 325 2.4E-34 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 698 744 4.5E-9 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 SUPERFAMILY SSF51971 199 444 2.88E-65 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Gene3D G3DSA:3.40.50.740 752 826 9.1E-10 T 13-10-2018 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 SMART SM00926 695 750 8.3E-7 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 Pfam PF00384 Molybdopterin oxidoreductase 752 1105 2.8E-24 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2294 be58307cb3f61106d627230c109cff02 1195 SUPERFAMILY SSF54292 11 108 5.37E-30 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 CLOST_2057 62acf00469b1e3699de43187265bc537 407 SMART SM00091 250 316 2.6E-6 T 13-10-2018 IPR000014 PAS domain CLOST_2057 62acf00469b1e3699de43187265bc537 407 Gene3D G3DSA:3.30.450.20 261 360 8.8E-9 T 13-10-2018 CLOST_2057 62acf00469b1e3699de43187265bc537 407 Pfam PF13426 PAS domain 260 353 6.1E-7 T 13-10-2018 IPR000014 PAS domain CLOST_2057 62acf00469b1e3699de43187265bc537 407 SUPERFAMILY SSF55785 247 309 3.32E-9 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2057 62acf00469b1e3699de43187265bc537 407 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 248 299 1.6E-6 T 13-10-2018 IPR000014 PAS domain CLOST_2057 62acf00469b1e3699de43187265bc537 407 Gene3D G3DSA:3.40.950.20 3 185 1.8E-12 T 13-10-2018 CLOST_2057 62acf00469b1e3699de43187265bc537 407 SUPERFAMILY SSF53920 1 202 1.83E-28 T 13-10-2018 IPR009016 Iron hydrogenase CLOST_2057 62acf00469b1e3699de43187265bc537 407 Pfam PF04060 Putative Fe-S cluster 212 242 1.4E-5 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 CLOST_2057 62acf00469b1e3699de43187265bc537 407 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 1 138 2.0E-24 T 13-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 Pfam PF14842 FliG N-terminal domain 11 113 5.8E-37 T 13-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 Gene3D G3DSA:1.10.220.30 201 340 8.8E-51 T 13-10-2018 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 SUPERFAMILY SSF48029 120 331 5.49E-71 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 Gene3D G3DSA:1.10.220.30 4 90 4.5E-21 T 13-10-2018 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 7 340 3.6E-138 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 Gene3D G3DSA:1.10.220.30 109 200 6.6E-35 T 13-10-2018 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 11 27 1.6E-76 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 278 304 1.6E-76 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 120 143 1.6E-76 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 254 274 1.6E-76 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 201 226 1.6E-76 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 232 252 1.6E-76 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 PRINTS PR00954 Flagellar motor switch protein FliG signature 40 66 1.6E-76 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 PIRSF PIRSF003161 5 340 4.5E-122 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 SUPERFAMILY SSF48029 11 106 1.23E-22 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 Pfam PF01706 FliG C-terminal domain 223 330 2.7E-45 T 13-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CLOST_1740 c3a5febdf944c50d46fbcf0dc1d3755d 340 Pfam PF14841 FliG middle domain 122 195 2.8E-31 T 13-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 Gene3D G3DSA:1.10.287.130 186 297 3.1E-6 T 13-10-2018 CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 9.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 9.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 9.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 9.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 SUPERFAMILY SSF47384 225 298 5.89E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 Gene3D G3DSA:3.30.565.10 298 456 4.9E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 SUPERFAMILY SSF55874 294 455 4.85E-31 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 455 7.1E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1019 47d1e04005fdea2e11a89b40c66bcf15 456 SMART SM00387 348 456 3.7E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0779 69d18283cdd5bf41a5327fbb173b483d 270 SUPERFAMILY SSF161098 10 257 1.68E-42 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0779 69d18283cdd5bf41a5327fbb173b483d 270 Gene3D G3DSA:1.10.3720.10 2 253 3.5E-38 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0779 69d18283cdd5bf41a5327fbb173b483d 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 251 3.0E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 143 514 4.8E-164 T 13-10-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 81 1.7E-20 T 13-10-2018 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 SMART SM00929 88 128 1.1E-20 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Gene3D G3DSA:4.10.260.20 518 577 1.7E-22 T 13-10-2018 IPR036991 Iron hydrogenase, small subunit superfamily CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Gene3D G3DSA:3.40.50.1780 210 513 3.6E-156 T 13-10-2018 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 126 1.1E-18 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Pfam PF13187 4Fe-4S dicluster domain 150 208 8.0E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 226 510 2.0E-101 T 13-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 SUPERFAMILY SSF54862 80 218 5.86E-38 T 13-10-2018 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Pfam PF02256 Iron hydrogenase small subunit 521 574 5.2E-26 T 13-10-2018 IPR003149 Iron hydrogenase, small subunit CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Gene3D G3DSA:3.10.20.740 1 128 7.0E-43 T 13-10-2018 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Gene3D G3DSA:3.40.950.10 275 504 3.6E-156 T 13-10-2018 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 SUPERFAMILY SSF54292 1 79 3.0E-16 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 SUPERFAMILY SSF53920 194 572 5.89E-135 T 13-10-2018 IPR009016 Iron hydrogenase CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 SMART SM00902 516 575 1.4E-28 T 13-10-2018 IPR003149 Iron hydrogenase, small subunit CLOST_0907 78ceb6cfeff697c740430d5f8accd261 577 Gene3D G3DSA:3.30.70.20 147 209 3.6E-156 T 13-10-2018 CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 12 40 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 1 116 2.3E-28 T 13-10-2018 CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 63 1.3E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 44 1.3E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 100 1.3E-15 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 Gene3D G3DSA:3.40.50.720 1 119 8.3E-33 T 13-10-2018 CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 SUPERFAMILY SSF51735 1 118 1.06E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 5 13 3.7E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_1964 e11afaf9d88e26cc56b0529db6905e68 121 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 25 44 3.7E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 Pfam PF00005 ABC transporter 23 189 6.0E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 SMART SM00382 301 501 16.0 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 SMART SM00382 32 237 1.3E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 SUPERFAMILY SSF52540 6 246 5.8E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 Pfam PF00005 ABC transporter 293 452 1.9E-16 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 SUPERFAMILY SSF52540 280 514 1.07E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 Gene3D G3DSA:3.40.50.300 2 257 9.2E-48 T 13-10-2018 CLOST_1005 08b24b67c9ef2d1fb1207a34af0709ab 533 Gene3D G3DSA:3.40.50.300 277 517 1.2E-39 T 13-10-2018 CLOST_1469 d9f4932482a1dccb6a19b062dddf04ea 199 SMART SM00855 3 155 3.0E-15 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CLOST_1469 d9f4932482a1dccb6a19b062dddf04ea 199 PIRSF PIRSF000709 2 193 2.2E-21 T 13-10-2018 CLOST_1469 d9f4932482a1dccb6a19b062dddf04ea 199 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 195 2.0E-56 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CLOST_1469 d9f4932482a1dccb6a19b062dddf04ea 199 SUPERFAMILY SSF53254 1 199 8.25E-54 T 13-10-2018 IPR029033 Histidine phosphatase superfamily CLOST_1469 d9f4932482a1dccb6a19b062dddf04ea 199 Gene3D G3DSA:3.40.50.1240 1 199 4.0E-62 T 13-10-2018 IPR029033 Histidine phosphatase superfamily CLOST_1205 ad9f664127db4d1ee0d84d809833ae23 331 PIRSF PIRSF009290 1 331 5.6E-84 T 13-10-2018 IPR024713 Fructosamine deglycase FrlB CLOST_1205 ad9f664127db4d1ee0d84d809833ae23 331 Gene3D G3DSA:3.40.50.10490 2 157 2.5E-31 T 13-10-2018 CLOST_1205 ad9f664127db4d1ee0d84d809833ae23 331 Gene3D G3DSA:3.40.50.10490 159 319 8.3E-44 T 13-10-2018 CLOST_1205 ad9f664127db4d1ee0d84d809833ae23 331 SUPERFAMILY SSF53697 22 330 1.64E-53 T 13-10-2018 CLOST_1205 ad9f664127db4d1ee0d84d809833ae23 331 Pfam PF01380 SIS domain 36 139 2.2E-14 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CLOST_1344 acac0398e88c58f2b0e8cac4ec947309 149 Pfam PF02681 Divergent PAP2 family 9 144 2.2E-52 T 13-10-2018 IPR003832 Protein of unknown function DUF212 CLOST_1344 acac0398e88c58f2b0e8cac4ec947309 149 SUPERFAMILY SSF48317 12 87 4.58E-5 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily CLOST_0572 a6feb9e085d312d66e4718b94fdf4503 342 Pfam PF01212 Beta-eliminating lyase 5 286 3.1E-95 T 13-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CLOST_0572 a6feb9e085d312d66e4718b94fdf4503 342 SUPERFAMILY SSF53383 3 339 3.46E-116 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0572 a6feb9e085d312d66e4718b94fdf4503 342 Gene3D G3DSA:3.40.640.10 1 246 2.8E-94 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0572 a6feb9e085d312d66e4718b94fdf4503 342 Gene3D G3DSA:3.90.1150.10 247 342 2.9E-21 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0572 a6feb9e085d312d66e4718b94fdf4503 342 PIRSF PIRSF017617 1 342 7.3E-131 T 13-10-2018 IPR023603 Threonine aldolase CLOST_0329 2d6aeb9762a22ed20597c64561409e06 166 Gene3D G3DSA:3.40.50.880 1 166 7.0E-48 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0329 2d6aeb9762a22ed20597c64561409e06 166 Pfam PF01965 DJ-1/PfpI family 2 164 3.3E-48 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 CLOST_0329 2d6aeb9762a22ed20597c64561409e06 166 SUPERFAMILY SSF52317 1 165 2.37E-43 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0329 2d6aeb9762a22ed20597c64561409e06 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 3 166 1.6E-48 T 13-10-2018 IPR006286 Deglycase PfpI CLOST_2462 73e8f8558749c269aef2d1aea9c724f3 335 Gene3D G3DSA:1.10.3470.10 7 335 5.5E-89 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_2462 73e8f8558749c269aef2d1aea9c724f3 335 SUPERFAMILY SSF81345 8 334 1.83E-76 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_2462 73e8f8558749c269aef2d1aea9c724f3 335 Pfam PF01032 FecCD transport family 21 334 1.6E-85 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 CLOST_2462 73e8f8558749c269aef2d1aea9c724f3 335 PRINTS PR00173 Glutamate-aspartate symporter signature 56 76 5.3E-6 T 13-10-2018 CLOST_2462 73e8f8558749c269aef2d1aea9c724f3 335 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 5.3E-6 T 13-10-2018 CLOST_2462 73e8f8558749c269aef2d1aea9c724f3 335 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 5.3E-6 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 PRINTS PR00681 Ribosomal protein S1 signature 152 172 5.8E-27 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 PRINTS PR00681 Ribosomal protein S1 signature 40 54 5.8E-27 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 PRINTS PR00681 Ribosomal protein S1 signature 22 40 5.8E-27 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 PRINTS PR00681 Ribosomal protein S1 signature 326 344 5.8E-27 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 PRINTS PR00681 Ribosomal protein S1 signature 82 101 5.8E-27 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 PRINTS PR00681 Ribosomal protein S1 signature 209 230 5.8E-27 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 PRINTS PR00681 Ribosomal protein S1 signature 287 306 5.8E-27 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 SMART SM00316 97 168 2.7E-7 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 SMART SM00316 272 343 1.4E-26 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 SMART SM00316 20 85 6.6E-11 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 SMART SM00316 187 257 1.6E-25 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 Gene3D G3DSA:2.40.50.140 94 180 5.8E-9 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 SUPERFAMILY SSF50249 187 269 3.07E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 SUPERFAMILY SSF50249 93 172 2.23E-9 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 SUPERFAMILY SSF50249 2 95 7.15E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 Gene3D G3DSA:2.40.50.140 264 345 9.6E-28 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 Gene3D G3DSA:2.40.50.140 183 263 4.2E-26 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 Gene3D G3DSA:2.40.50.140 9 93 1.8E-15 T 13-10-2018 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 SUPERFAMILY SSF50249 257 342 5.08E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 Pfam PF00575 S1 RNA binding domain 21 85 2.1E-8 T 13-10-2018 IPR003029 S1 domain GO:0003676 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 Pfam PF00575 S1 RNA binding domain 185 257 4.9E-22 T 13-10-2018 IPR003029 S1 domain GO:0003676 CLOST_1465 6fa9d2e3c5dacfc6b2b26fc51e5daa86 358 Pfam PF00575 S1 RNA binding domain 272 342 1.7E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 CLOST_1379 ae6a1c4183a25d99eaff708fc8c19702 519 Pfam PF09043 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 8 515 2.5E-275 T 13-10-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CLOST_1379 ae6a1c4183a25d99eaff708fc8c19702 519 SUPERFAMILY SSF51703 6 518 2.82E-236 T 13-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CLOST_1379 ae6a1c4183a25d99eaff708fc8c19702 519 Gene3D G3DSA:3.20.20.440 4 519 4.0E-253 T 13-10-2018 IPR037086 D-Lysine 5,6-aminomutase alpha subunit superfamily CLOST_2015 14f74ca53084f4a09381f2a3b9e73e97 68 SUPERFAMILY SSF64307 1 60 1.31E-13 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_2015 14f74ca53084f4a09381f2a3b9e73e97 68 Gene3D G3DSA:3.30.110.40 1 67 2.3E-21 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_2015 14f74ca53084f4a09381f2a3b9e73e97 68 Pfam PF01206 Sulfurtransferase TusA 2 65 1.7E-17 T 13-10-2018 IPR001455 TusA-like domain CLOST_0550 18637b4ab622d09ffc419ceec1265971 217 Pfam PF12654 Domain of unknown function (DUF3786) 36 196 1.3E-47 T 13-10-2018 IPR024264 Domain of unknown function DUF3786 CLOST_1499 19c6874d166edb8fd645ad3392a84285 356 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 65 281 3.4E-74 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CLOST_1499 19c6874d166edb8fd645ad3392a84285 356 Gene3D G3DSA:3.40.50.450 4 288 4.5E-90 T 13-10-2018 CLOST_1499 19c6874d166edb8fd645ad3392a84285 356 SUPERFAMILY SSF102405 75 281 3.36E-36 T 13-10-2018 CLOST_1499 19c6874d166edb8fd645ad3392a84285 356 Pfam PF02481 DNA recombination-mediator protein A 66 273 2.3E-76 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CLOST_1618 b710963a15ba0b32e4c56b3d9dc5c8a9 295 Pfam PF00892 EamA-like transporter family 151 285 6.1E-23 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_1618 b710963a15ba0b32e4c56b3d9dc5c8a9 295 Pfam PF00892 EamA-like transporter family 7 140 3.3E-26 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_1618 b710963a15ba0b32e4c56b3d9dc5c8a9 295 SUPERFAMILY SSF103481 185 289 6.41E-17 T 13-10-2018 CLOST_1618 b710963a15ba0b32e4c56b3d9dc5c8a9 295 SUPERFAMILY SSF103481 41 143 2.62E-13 T 13-10-2018 CLOST_2455 60deacd6996f70dc66848fa9e005c217 111 Gene3D G3DSA:2.20.25.10 1 38 1.5E-18 T 13-10-2018 CLOST_2455 60deacd6996f70dc66848fa9e005c217 111 Pfam PF03831 PhnA domain 43 110 1.3E-34 T 13-10-2018 IPR013988 PhnA protein, C-terminal CLOST_2455 60deacd6996f70dc66848fa9e005c217 111 SUPERFAMILY SSF57783 2 31 3.74E-13 T 13-10-2018 CLOST_2455 60deacd6996f70dc66848fa9e005c217 111 Pfam PF08274 PhnA Zinc-Ribbon 2 30 4.6E-15 T 13-10-2018 IPR013987 PhnA protein, N-terminal CLOST_2455 60deacd6996f70dc66848fa9e005c217 111 Gene3D G3DSA:2.30.30.40 41 111 4.3E-34 T 13-10-2018 CLOST_2455 60deacd6996f70dc66848fa9e005c217 111 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 110 2.8E-46 T 13-10-2018 IPR004624 PhnA protein CLOST_2455 60deacd6996f70dc66848fa9e005c217 111 SUPERFAMILY SSF82057 41 110 1.14E-26 T 13-10-2018 CLOST_0674 b29d4dbab68ff6e3ce03c2ca280ec5a9 503 Gene3D G3DSA:3.40.605.10 62 265 2.1E-116 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 CLOST_0674 b29d4dbab68ff6e3ce03c2ca280ec5a9 503 SUPERFAMILY SSF53720 59 495 1.7E-60 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 CLOST_0674 b29d4dbab68ff6e3ce03c2ca280ec5a9 503 Pfam PF00171 Aldehyde dehydrogenase family 54 456 3.4E-30 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 CLOST_0674 b29d4dbab68ff6e3ce03c2ca280ec5a9 503 PIRSF PIRSF036410 11 503 1.1E-190 T 13-10-2018 IPR012408 Acetaldehyde/propionaldehyde dehydrogenase, EutE/PduP-related CLOST_0674 b29d4dbab68ff6e3ce03c2ca280ec5a9 503 Gene3D G3DSA:3.40.309.10 266 457 2.1E-116 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 CLOST_1931 02713199abb6ef6ad27805bb16a0ed24 57 SUPERFAMILY SSF158221 1 42 1.7E-12 T 13-10-2018 CLOST_1931 02713199abb6ef6ad27805bb16a0ed24 57 Hamap MF_01103 UPF0291 protein . 1 57 12.646 T 13-10-2018 IPR009242 Protein of unknown function DUF896 CLOST_1931 02713199abb6ef6ad27805bb16a0ed24 57 Gene3D G3DSA:1.10.287.540 2 57 5.6E-18 T 13-10-2018 CLOST_1931 02713199abb6ef6ad27805bb16a0ed24 57 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 55 2.2E-17 T 13-10-2018 IPR009242 Protein of unknown function DUF896 CLOST_2079 76c97449bd792be6566f0da33196069a 456 PIRSF PIRSF006603 2 455 2.6E-79 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_2079 76c97449bd792be6566f0da33196069a 456 Pfam PF01554 MatE 26 186 5.8E-33 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_2079 76c97449bd792be6566f0da33196069a 456 Pfam PF01554 MatE 252 414 1.8E-18 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_2079 76c97449bd792be6566f0da33196069a 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 422 5.3E-71 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_2079 76c97449bd792be6566f0da33196069a 456 PRINTS PR00173 Glutamate-aspartate symporter signature 304 324 3.7E-5 T 13-10-2018 CLOST_2079 76c97449bd792be6566f0da33196069a 456 PRINTS PR00173 Glutamate-aspartate symporter signature 19 39 3.7E-5 T 13-10-2018 CLOST_2079 76c97449bd792be6566f0da33196069a 456 PRINTS PR00173 Glutamate-aspartate symporter signature 277 296 3.7E-5 T 13-10-2018 CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 SUPERFAMILY SSF56420 3 146 5.63E-55 T 13-10-2018 IPR036821 Peptide deformylase superfamily CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 Hamap MF_00163 Peptide deformylase [def]. 2 152 28.258 T 13-10-2018 IPR023635 Peptide deformylase CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 149 3.0E-46 T 13-10-2018 IPR023635 Peptide deformylase CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 Pfam PF01327 Polypeptide deformylase 4 146 3.6E-47 T 13-10-2018 IPR023635 Peptide deformylase CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 Gene3D G3DSA:3.90.45.10 1 152 3.6E-54 T 13-10-2018 IPR036821 Peptide deformylase superfamily CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 PRINTS PR01576 Peptide deformylase signature 33 62 7.8E-30 T 13-10-2018 IPR023635 Peptide deformylase CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 PRINTS PR01576 Peptide deformylase signature 98 116 7.8E-30 T 13-10-2018 IPR023635 Peptide deformylase CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 PRINTS PR01576 Peptide deformylase signature 117 146 7.8E-30 T 13-10-2018 IPR023635 Peptide deformylase CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 PRINTS PR01576 Peptide deformylase signature 86 97 7.8E-30 T 13-10-2018 IPR023635 Peptide deformylase CLOST_1856 d5a634e515c59ba3e8b560012074182a 152 PIRSF PIRSF004749 1 151 7.5E-50 T 13-10-2018 IPR023635 Peptide deformylase CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 194 398 2.2E-20 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 SMART SM00357 92 156 1.1E-13 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 Pfam PF07497 Rho termination factor, RNA-binding domain 92 163 1.3E-30 T 13-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 SUPERFAMILY SSF50249 86 151 3.51E-6 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 SUPERFAMILY SSF52540 128 406 2.36E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 SMART SM00382 204 390 1.7E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 TIGRFAM TIGR00767 rho: transcription termination factor Rho 3 451 3.8E-181 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 Pfam PF07498 Rho termination factor, N-terminal domain 3 42 3.7E-5 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 Gene3D G3DSA:3.40.50.300 169 452 8.6E-119 T 13-10-2018 CLOST_2137 8a5594f10c80632dbeeedf1d86f1866a 457 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 454 186.523 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CLOST_2004 f88213c40604ebcb51ca57d6320f1fe3 246 Gene3D G3DSA:3.30.457.10 157 234 4.5E-20 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_2004 f88213c40604ebcb51ca57d6320f1fe3 246 SUPERFAMILY SSF55383 155 239 9.81E-24 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_2004 f88213c40604ebcb51ca57d6320f1fe3 246 Pfam PF07833 Copper amine oxidase N-terminal domain 153 243 5.9E-25 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_2004 f88213c40604ebcb51ca57d6320f1fe3 246 Pfam PF07833 Copper amine oxidase N-terminal domain 132 175 5.0E-8 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_2559 bf2064f726d5a5d95e8daa3301eefc87 328 Gene3D G3DSA:3.40.50.300 121 315 2.0E-41 T 13-10-2018 CLOST_2559 bf2064f726d5a5d95e8daa3301eefc87 328 SUPERFAMILY SSF52540 165 318 8.3E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2559 bf2064f726d5a5d95e8daa3301eefc87 328 SMART SM00382 183 316 5.9E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2559 bf2064f726d5a5d95e8daa3301eefc87 328 Pfam PF01695 IstB-like ATP binding protein 171 307 9.2E-17 T 13-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 632 34.766 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Pfam PF03129 Anticodon binding domain 539 626 8.8E-22 T 13-10-2018 IPR004154 Anticodon-binding CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 317 527 2.7E-41 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Pfam PF02824 TGS domain 2 61 4.4E-12 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Gene3D G3DSA:3.30.54.20 130 186 8.4E-66 T 13-10-2018 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 629 1.3E-222 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 SUPERFAMILY SSF55186 64 239 4.06E-64 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Gene3D G3DSA:3.40.50.800 530 637 3.2E-35 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Gene3D G3DSA:3.30.930.10 221 529 3.5E-132 T 13-10-2018 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.7E-13 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 SUPERFAMILY SSF55681 242 524 1.13E-94 T 13-10-2018 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 SMART SM00863 169 218 2.4E-21 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Gene3D G3DSA:3.10.20.30 1 64 2.8E-20 T 13-10-2018 IPR012675 Beta-grasp domain superfamily CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 SUPERFAMILY SSF52954 527 630 1.33E-32 T 13-10-2018 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 8.5E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 518 8.5E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 8.5E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 462 490 8.5E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 PRINTS PR01047 Threonyl-tRNA synthetase signature 532 544 8.5E-52 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 Gene3D G3DSA:3.30.980.10 69 220 8.4E-66 T 13-10-2018 CLOST_1127 4ab56dc54d5653d7e63d52b57b57ea29 637 SUPERFAMILY SSF81271 2 61 7.85E-14 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 Pfam PF11741 AMIN domain 257 337 4.7E-11 T 13-10-2018 IPR021731 AMIN domain CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 SUPERFAMILY SSF53187 460 633 1.41E-53 T 13-10-2018 CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 SUPERFAMILY SSF55383 70 156 1.57E-22 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 SMART SM00646 519 629 1.7E-36 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 Gene3D G3DSA:3.30.457.10 71 151 4.6E-21 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 Pfam PF07833 Copper amine oxidase N-terminal domain 68 159 1.1E-26 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 461 629 8.9E-51 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 Gene3D G3DSA:2.60.40.3500 227 346 1.0E-10 T 13-10-2018 CLOST_0587 c22edf8f0f48dc2c78d157c96d414444 635 Gene3D G3DSA:3.40.630.40 458 634 7.5E-61 T 13-10-2018 CLOST_2516 c47dbc691ab2e838387e09d07c66828e 590 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 76 524 2.6E-20 T 13-10-2018 IPR026487 Sporadically distributed protein CHP04141 CLOST_1347 e967ea136e5647710f4b4ce61bcf5c84 403 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 391 22.75 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CLOST_1347 e967ea136e5647710f4b4ce61bcf5c84 403 Pfam PF13742 OB-fold nucleic acid binding domain 6 95 1.8E-21 T 13-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CLOST_1347 e967ea136e5647710f4b4ce61bcf5c84 403 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 7 390 3.7E-122 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CLOST_1347 e967ea136e5647710f4b4ce61bcf5c84 403 Pfam PF02601 Exonuclease VII, large subunit 307 388 4.1E-9 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CLOST_1347 e967ea136e5647710f4b4ce61bcf5c84 403 Pfam PF02601 Exonuclease VII, large subunit 120 337 2.0E-64 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CLOST_1382 4b39b5cb9e4b6619cd740397ae14ce3c 414 Pfam PF04055 Radical SAM superfamily 121 268 1.4E-11 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1382 4b39b5cb9e4b6619cd740397ae14ce3c 414 Gene3D G3DSA:2.40.50.600 339 400 5.4E-28 T 13-10-2018 CLOST_1382 4b39b5cb9e4b6619cd740397ae14ce3c 414 Pfam PF12544 Lysine-2,3-aminomutase 311 412 2.8E-40 T 13-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain CLOST_1382 4b39b5cb9e4b6619cd740397ae14ce3c 414 Gene3D G3DSA:3.20.20.70 53 338 8.5E-125 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1382 4b39b5cb9e4b6619cd740397ae14ce3c 414 SUPERFAMILY SSF102114 104 386 1.83E-34 T 13-10-2018 CLOST_1382 4b39b5cb9e4b6619cd740397ae14ce3c 414 PIRSF PIRSF004911 1 401 8.0E-171 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CLOST_1382 4b39b5cb9e4b6619cd740397ae14ce3c 414 TIGRFAM TIGR00238 TIGR00238: KamA family protein 8 332 1.4E-125 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CLOST_1382 4b39b5cb9e4b6619cd740397ae14ce3c 414 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 12 411 1.0E-194 T 13-10-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Gene3D G3DSA:3.40.920.10 415 625 9.0E-91 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 SUPERFAMILY SSF54862 668 836 2.93E-19 T 13-10-2018 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 SMART SM00890 623 681 3.1E-26 T 13-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 SUPERFAMILY SSF52518 5 258 3.53E-78 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Pfam PF10371 Domain of unknown function 632 680 7.5E-22 T 13-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Gene3D G3DSA:3.40.50.970 790 1177 8.8E-178 T 13-10-2018 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Gene3D G3DSA:3.30.70.20 671 788 2.8E-42 T 13-10-2018 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 PIRSF PIRSF000159 1 1178 0.0 T 13-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 SUPERFAMILY SSF52922 259 413 1.1E-48 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 SUPERFAMILY SSF52518 791 1178 1.35E-134 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Gene3D G3DSA:3.40.50.970 2 258 2.3E-110 T 13-10-2018 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Gene3D G3DSA:3.40.50.920 259 412 4.2E-58 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 SUPERFAMILY SSF53323 416 667 4.45E-85 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 747 758 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 691 702 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Gene3D G3DSA:4.10.780.10 632 670 4.3E-7 T 13-10-2018 IPR037112 Pyruvate-flavodoxin oxidoreductase, EKR domain superfamily CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 248 4.7E-80 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Pfam PF13484 4Fe-4S double cluster binding domain 690 758 2.9E-9 T 13-10-2018 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 425 608 5.0E-34 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 961 1073 3.5E-11 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 5 1175 0.0 T 13-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 CLOST_1913 15802760fbdc12d937664920a667a2fe 1178 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 269 373 1.8E-15 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CLOST_1987 57761780f140480322692d8eb1300a16 626 Gene3D G3DSA:3.30.565.10 1 228 1.1E-73 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1987 57761780f140480322692d8eb1300a16 626 Pfam PF00183 Hsp90 protein 216 625 7.7E-109 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 CLOST_1987 57761780f140480322692d8eb1300a16 626 Pfam PF00183 Hsp90 protein 184 223 9.2E-6 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 CLOST_1987 57761780f140480322692d8eb1300a16 626 SUPERFAMILY SSF54211 236 488 9.1E-78 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_1987 57761780f140480322692d8eb1300a16 626 PRINTS PR00775 90kDa heat shock protein signature 188 206 2.4E-54 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal CLOST_1987 57761780f140480322692d8eb1300a16 626 PRINTS PR00775 90kDa heat shock protein signature 23 45 2.4E-54 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal CLOST_1987 57761780f140480322692d8eb1300a16 626 PRINTS PR00775 90kDa heat shock protein signature 72 89 2.4E-54 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal CLOST_1987 57761780f140480322692d8eb1300a16 626 PRINTS PR00775 90kDa heat shock protein signature 90 107 2.4E-54 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal CLOST_1987 57761780f140480322692d8eb1300a16 626 PRINTS PR00775 90kDa heat shock protein signature 115 137 2.4E-54 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal CLOST_1987 57761780f140480322692d8eb1300a16 626 PRINTS PR00775 90kDa heat shock protein signature 165 182 2.4E-54 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal CLOST_1987 57761780f140480322692d8eb1300a16 626 PRINTS PR00775 90kDa heat shock protein signature 2 22 2.4E-54 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal CLOST_1987 57761780f140480322692d8eb1300a16 626 Gene3D G3DSA:3.40.50.11260 408 494 5.9E-27 T 13-10-2018 CLOST_1987 57761780f140480322692d8eb1300a16 626 SUPERFAMILY SSF55874 2 211 2.74E-62 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1987 57761780f140480322692d8eb1300a16 626 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 150 8.7E-13 T 13-10-2018 CLOST_1987 57761780f140480322692d8eb1300a16 626 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 626 26.888 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 CLOST_1987 57761780f140480322692d8eb1300a16 626 Gene3D G3DSA:3.30.230.80 235 407 2.7E-54 T 13-10-2018 CLOST_1987 57761780f140480322692d8eb1300a16 626 Gene3D G3DSA:1.20.120.790 495 626 1.7E-34 T 13-10-2018 IPR037196 HSP90, C-terminal domain CLOST_1987 57761780f140480322692d8eb1300a16 626 PIRSF PIRSF002583 1 626 2.2E-199 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 CLOST_1987 57761780f140480322692d8eb1300a16 626 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 22 31 - T 13-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 CLOST_1987 57761780f140480322692d8eb1300a16 626 SUPERFAMILY SSF110942 511 625 9.15E-29 T 13-10-2018 IPR037196 HSP90, C-terminal domain CLOST_0976 5b2ebbe66877acd7e1457043661e3f87 176 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 4 175 1.1E-60 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 CLOST_0976 5b2ebbe66877acd7e1457043661e3f87 176 PIRSF PIRSF015617 1 176 4.4E-59 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 CLOST_0976 5b2ebbe66877acd7e1457043661e3f87 176 SUPERFAMILY SSF52540 2 175 7.3E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0976 5b2ebbe66877acd7e1457043661e3f87 176 Gene3D G3DSA:3.40.50.300 1 175 4.1E-64 T 13-10-2018 CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 SUPERFAMILY SSF50331 248 338 9.07E-12 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 Gene3D G3DSA:3.40.50.300 1 238 1.9E-72 T 13-10-2018 CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 Pfam PF08402 TOBE domain 260 337 1.1E-5 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 Pfam PF00005 ABC transporter 19 162 1.4E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 SUPERFAMILY SSF52540 4 243 4.79E-79 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 Gene3D G3DSA:2.40.50.140 262 330 5.6E-8 T 13-10-2018 CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 Gene3D G3DSA:2.40.50.100 251 338 5.6E-8 T 13-10-2018 CLOST_0075 d812cfd22761064ce727d04a5a70fee3 338 SMART SM00382 28 211 2.6E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0599 3a212e62f3b367b0811b6738e0916bd6 531 Gene3D G3DSA:3.50.50.60 85 299 1.4E-77 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0599 3a212e62f3b367b0811b6738e0916bd6 531 Gene3D G3DSA:3.50.50.60 466 529 3.7E-13 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0599 3a212e62f3b367b0811b6738e0916bd6 531 PIRSF PIRSF038984 1 531 3.1E-216 T 13-10-2018 IPR028348 FAD dependent protein CLOST_0599 3a212e62f3b367b0811b6738e0916bd6 531 SUPERFAMILY SSF51905 94 523 3.89E-32 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0599 3a212e62f3b367b0811b6738e0916bd6 531 Pfam PF00890 FAD binding domain 97 127 1.1E-5 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CLOST_0599 3a212e62f3b367b0811b6738e0916bd6 531 Gene3D G3DSA:3.30.70.2700 1 78 3.5E-15 T 13-10-2018 CLOST_0465 0c2908a1ea22d4571d5b4444523ec993 256 PIRSF PIRSF005902 1 256 6.2E-84 T 13-10-2018 IPR001130 TatD family GO:0016788 CLOST_0465 0c2908a1ea22d4571d5b4444523ec993 256 Gene3D G3DSA:3.20.20.140 1 255 7.1E-104 T 13-10-2018 CLOST_0465 0c2908a1ea22d4571d5b4444523ec993 256 Pfam PF01026 TatD related DNase 4 253 6.0E-83 T 13-10-2018 IPR001130 TatD family GO:0016788 CLOST_0465 0c2908a1ea22d4571d5b4444523ec993 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 253 8.6E-89 T 13-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CLOST_0465 0c2908a1ea22d4571d5b4444523ec993 256 SUPERFAMILY SSF51556 3 254 8.13E-90 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_0465 0c2908a1ea22d4571d5b4444523ec993 256 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 104 256 0.001 T 13-10-2018 CLOST_0465 0c2908a1ea22d4571d5b4444523ec993 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 Gene3D G3DSA:2.40.50.140 2 82 6.6E-8 T 13-10-2018 CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 Gene3D G3DSA:1.20.1440.120 89 237 3.3E-17 T 13-10-2018 CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 246 2.6E-51 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 Pfam PF02565 Recombination protein O C terminal 83 241 1.7E-26 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 SUPERFAMILY SSF57863 81 235 2.09E-30 T 13-10-2018 IPR037278 ARFGAP/RecO-like zinc finger CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 Pfam PF11967 Recombination protein O N terminal 1 78 8.2E-17 T 13-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 Hamap MF_00201 DNA repair protein RecO [recO]. 1 248 25.151 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 SUPERFAMILY SSF50249 1 78 8.05E-13 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1773 b04ef5da39bc8bc0eea40cb58bbf8286 248 Gene3D G3DSA:3.30.60.100 148 189 3.3E-17 T 13-10-2018 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 13-10-2018 IPR020610 Thiolase, active site GO:0016747 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 Pfam PF02803 Thiolase, C-terminal domain 270 390 6.2E-49 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 13-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 3.4E-146 T 13-10-2018 IPR002155 Thiolase GO:0016747 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 13-10-2018 IPR020613 Thiolase, conserved site GO:0016747 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 Gene3D G3DSA:3.40.47.10 126 389 5.9E-156 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 Gene3D G3DSA:3.40.47.10 6 275 5.9E-156 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 Pfam PF00108 Thiolase, N-terminal domain 4 262 9.2E-105 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 PIRSF PIRSF000429 1 391 1.3E-134 T 13-10-2018 IPR002155 Thiolase GO:0016747 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 SUPERFAMILY SSF53901 3 269 7.02E-91 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_1134 d04bfc3e84d9977c8f4ba8a547ab7ed7 391 SUPERFAMILY SSF53901 271 390 3.6E-41 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_2347 9d3dbe9091f03bc68265e5ac65d356de 141 Pfam PF02623 FliW protein 20 134 1.8E-34 T 13-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CLOST_2347 9d3dbe9091f03bc68265e5ac65d356de 141 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 138 22.802 T 13-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CLOST_2347 9d3dbe9091f03bc68265e5ac65d356de 141 SUPERFAMILY SSF141457 2 137 2.09E-41 T 13-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily CLOST_2347 9d3dbe9091f03bc68265e5ac65d356de 141 Gene3D G3DSA:2.30.290.10 1 140 8.2E-45 T 13-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 SUPERFAMILY SSF48452 20 119 4.17E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 Pfam PF13181 Tetratricopeptide repeat 167 197 0.0055 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 SUPERFAMILY SSF48452 86 303 2.91E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 Pfam PF00990 Diguanylate cyclase, GGDEF domain 377 533 3.0E-38 T 13-10-2018 IPR000160 GGDEF domain CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 Pfam PF13424 Tetratricopeptide repeat 86 154 2.1E-12 T 13-10-2018 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 Gene3D G3DSA:1.25.40.10 8 164 1.2E-23 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 Gene3D G3DSA:1.25.40.10 165 318 3.0E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 SUPERFAMILY SSF55073 381 539 6.2E-38 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 536 1.7E-39 T 13-10-2018 IPR000160 GGDEF domain CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 SMART SM00028 45 78 49.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 SMART SM00028 165 198 0.65 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 SMART SM00028 125 158 8.1E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 SMART SM00028 85 118 2.1 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 SMART SM00267 365 538 8.7E-47 T 13-10-2018 IPR000160 GGDEF domain CLOST_2052 f85d9471107a983d4e9b6d56caa0779e 540 Gene3D G3DSA:3.30.70.270 361 539 5.9E-40 T 13-10-2018 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 TIGRFAM TIGR00492 alr: alanine racemase 6 370 2.6E-121 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 SMART SM01005 247 371 1.8E-57 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 128 140 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 163 174 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 301 318 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 31 47 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 67 85 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 353 366 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 263 278 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 206 233 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 PRINTS PR00992 Alanine racemase signature 280 295 8.3E-64 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 SUPERFAMILY SSF50621 242 381 2.93E-44 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 SUPERFAMILY SSF51419 12 248 8.04E-68 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 Pfam PF00842 Alanine racemase, C-terminal domain 247 370 2.7E-43 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 13-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 Hamap MF_01201 Alanine racemase. 5 371 33.342 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 Gene3D G3DSA:3.20.20.10 14 228 8.9E-131 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 Gene3D G3DSA:2.40.37.10 10 370 8.9E-131 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CLOST_2112 fba3a707e28cde6fece9595b5192105b 384 Pfam PF01168 Alanine racemase, N-terminal domain 12 233 2.3E-70 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 Pfam PF00005 ABC transporter 19 195 5.0E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 SMART SM00382 357 523 1.2E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 SMART SM00382 28 242 6.4E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 Pfam PF00005 ABC transporter 349 478 2.8E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 SUPERFAMILY SSF52540 313 535 3.1E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 Gene3D G3DSA:3.40.50.300 2 292 1.5E-63 T 13-10-2018 CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 Gene3D G3DSA:3.40.50.300 295 559 8.8E-65 T 13-10-2018 CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 Pfam PF12848 ABC transporter 234 319 2.0E-19 T 13-10-2018 IPR032781 ABC-transporter extension domain CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 SUPERFAMILY SSF52540 4 256 1.05E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2298 687944bf9c62ff21f178dfb04d9c94a2 644 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2238 3274b3e227555b5811444a6d31c617d0 162 Pfam PF04073 Aminoacyl-tRNA editing domain 23 148 1.7E-29 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CLOST_2238 3274b3e227555b5811444a6d31c617d0 162 SUPERFAMILY SSF55826 3 161 2.35E-43 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 CLOST_2238 3274b3e227555b5811444a6d31c617d0 162 Gene3D G3DSA:3.90.960.10 1 162 5.6E-50 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 CLOST_1888 7b72279818cbeccc67cdfe93cb75594a 230 SUPERFAMILY SSF46894 132 229 1.34E-31 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_1888 7b72279818cbeccc67cdfe93cb75594a 230 SUPERFAMILY SSF52172 2 130 1.71E-43 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1888 7b72279818cbeccc67cdfe93cb75594a 230 Gene3D G3DSA:1.10.10.10 130 230 2.4E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1888 7b72279818cbeccc67cdfe93cb75594a 230 Pfam PF00072 Response regulator receiver domain 5 117 9.0E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1888 7b72279818cbeccc67cdfe93cb75594a 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 5.9E-30 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1888 7b72279818cbeccc67cdfe93cb75594a 230 SMART SM00862 153 229 4.6E-30 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1888 7b72279818cbeccc67cdfe93cb75594a 230 Gene3D G3DSA:3.40.50.2300 1 129 1.9E-40 T 13-10-2018 CLOST_1888 7b72279818cbeccc67cdfe93cb75594a 230 SMART SM00448 3 116 8.8E-43 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0086 e86f5f52f5b27235838e9bd681383d0e 320 SMART SM00382 35 227 5.4E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0086 e86f5f52f5b27235838e9bd681383d0e 320 Gene3D G3DSA:3.40.50.300 4 319 4.4E-94 T 13-10-2018 CLOST_0086 e86f5f52f5b27235838e9bd681383d0e 320 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 294 5.0E-12 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0086 e86f5f52f5b27235838e9bd681383d0e 320 SUPERFAMILY SSF52540 6 248 5.94E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0086 e86f5f52f5b27235838e9bd681383d0e 320 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0086 e86f5f52f5b27235838e9bd681383d0e 320 Pfam PF00005 ABC transporter 26 177 2.3E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0086 e86f5f52f5b27235838e9bd681383d0e 320 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 227 313 1.2E-15 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_1971 8cd718de9a0fcfc37555167468bcc3cf 128 PIRSF PIRSF021774 2 127 5.8E-37 T 13-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 CLOST_1971 8cd718de9a0fcfc37555167468bcc3cf 128 Gene3D G3DSA:3.30.310.70 3 127 7.2E-43 T 13-10-2018 IPR035923 TT1751-like domain superfamily CLOST_1971 8cd718de9a0fcfc37555167468bcc3cf 128 SUPERFAMILY SSF103247 4 125 8.63E-34 T 13-10-2018 IPR035923 TT1751-like domain superfamily CLOST_1971 8cd718de9a0fcfc37555167468bcc3cf 128 Pfam PF03625 Domain of unknown function DUF302 36 97 8.8E-19 T 13-10-2018 IPR005180 Domain of unknown function DUF302 CLOST_0723 5610a6327fdaf4900b26b8740652d7cd 237 Gene3D G3DSA:3.40.50.1580 3 237 9.6E-67 T 13-10-2018 CLOST_0723 5610a6327fdaf4900b26b8740652d7cd 237 Pfam PF01048 Phosphorylase superfamily 18 232 3.6E-35 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CLOST_0723 5610a6327fdaf4900b26b8740652d7cd 237 SUPERFAMILY SSF53167 4 236 3.14E-77 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 CLOST_0723 5610a6327fdaf4900b26b8740652d7cd 237 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 6 235 9.8E-84 T 13-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 SUPERFAMILY SSF52540 60 396 3.44E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 406 5.4E-200 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 SMART SM00994 9 48 8.4E-24 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 108 305 3.1E-49 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 SMART SM01086 312 406 1.1E-29 T 13-10-2018 IPR019489 Clp ATPase, C-terminal CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 Gene3D G3DSA:1.10.8.60 311 419 3.1E-38 T 13-10-2018 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 410 52.6 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 Gene3D G3DSA:3.40.50.300 53 310 3.7E-106 T 13-10-2018 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 Pfam PF06689 ClpX C4-type zinc finger 10 47 8.2E-21 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 2.3E-14 T 13-10-2018 IPR019489 Clp ATPase, C-terminal CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 SUPERFAMILY SSF57716 10 45 4.56E-12 T 13-10-2018 CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 Gene3D G3DSA:3.30.50.30 2 49 1.9E-22 T 13-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily CLOST_0591 fa1c45630e9e23a3e7088fd68e34f9cc 421 SMART SM00382 108 265 5.2E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1498 529ce626e753380e26b99e4510310339 684 SMART SM00437 243 506 2.3E-111 T 13-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 637 54.296 T 13-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 Gene3D G3DSA:2.70.20.10 184 453 1.3E-155 T 13-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CLOST_1498 529ce626e753380e26b99e4510310339 684 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 4.8E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 4.8E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 371 387 4.8E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 469 483 4.8E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 294 303 4.8E-35 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 Gene3D G3DSA:1.10.290.10 251 386 1.3E-155 T 13-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 CLOST_1498 529ce626e753380e26b99e4510310339 684 SMART SM00436 104 192 1.4E-46 T 13-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 Pfam PF01131 DNA topoisomerase 128 543 5.5E-131 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 Gene3D G3DSA:3.40.50.140 1 134 1.3E-56 T 13-10-2018 CLOST_1498 529ce626e753380e26b99e4510310339 684 SUPERFAMILY SSF57783 570 607 2.49E-12 T 13-10-2018 CLOST_1498 529ce626e753380e26b99e4510310339 684 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 572 606 3.4E-14 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CLOST_1498 529ce626e753380e26b99e4510310339 684 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 612 651 2.9E-14 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CLOST_1498 529ce626e753380e26b99e4510310339 684 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 652 682 0.5 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CLOST_1498 529ce626e753380e26b99e4510310339 684 Gene3D G3DSA:1.10.460.10 135 546 1.3E-155 T 13-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CLOST_1498 529ce626e753380e26b99e4510310339 684 SUPERFAMILY SSF56712 3 584 6.54E-197 T 13-10-2018 IPR023405 DNA topoisomerase, type IA, core domain CLOST_1498 529ce626e753380e26b99e4510310339 684 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 606 3.2E-241 T 13-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CLOST_1498 529ce626e753380e26b99e4510310339 684 SMART SM00493 3 103 3.7E-30 T 13-10-2018 IPR006171 TOPRIM domain CLOST_1498 529ce626e753380e26b99e4510310339 684 Pfam PF01751 Toprim domain 5 113 3.5E-31 T 13-10-2018 IPR006171 TOPRIM domain CLOST_1498 529ce626e753380e26b99e4510310339 684 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 280 303 - T 13-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CLOST_1498 529ce626e753380e26b99e4510310339 684 Gene3D G3DSA:3.30.65.10 558 612 1.0E-11 T 13-10-2018 CLOST_1772 6c8e703490192e4f08f6616960c01ffc 168 Gene3D G3DSA:1.10.8.10 3 39 5.7E-7 T 13-10-2018 CLOST_1772 6c8e703490192e4f08f6616960c01ffc 168 SUPERFAMILY SSF46934 2 45 3.44E-8 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 CLOST_1772 6c8e703490192e4f08f6616960c01ffc 168 Pfam PF14242 Domain of unknown function (DUF4342) 44 119 1.6E-25 T 13-10-2018 IPR025642 Domain of unknown function DUF4342 CLOST_0042 2fb997c91b9c11a310d6695a00b30daf 282 SUPERFAMILY SSF53335 3 280 2.44E-84 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0042 2fb997c91b9c11a310d6695a00b30daf 282 TIGRFAM TIGR00417 speE: spermidine synthase 4 274 4.8E-98 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CLOST_0042 2fb997c91b9c11a310d6695a00b30daf 282 Gene3D G3DSA:3.40.50.150 53 281 1.7E-75 T 13-10-2018 CLOST_0042 2fb997c91b9c11a310d6695a00b30daf 282 Gene3D G3DSA:2.30.140.10 1 52 9.3E-21 T 13-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CLOST_0042 2fb997c91b9c11a310d6695a00b30daf 282 Pfam PF01564 Spermine/spermidine synthase domain 58 243 2.2E-56 T 13-10-2018 CLOST_0042 2fb997c91b9c11a310d6695a00b30daf 282 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 13-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CLOST_0042 2fb997c91b9c11a310d6695a00b30daf 282 Pfam PF17284 Spermidine synthase tetramerisation domain 3 55 1.1E-18 T 13-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CLOST_0042 2fb997c91b9c11a310d6695a00b30daf 282 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 280 40.111 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CLOST_1226 400fd861402729b09550d51eb4ee010b 131 SUPERFAMILY SSF52402 4 100 1.16E-8 T 13-10-2018 CLOST_1226 400fd861402729b09550d51eb4ee010b 131 Gene3D G3DSA:3.40.50.620 1 113 2.5E-7 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1226 400fd861402729b09550d51eb4ee010b 131 Pfam PF00582 Universal stress protein family 4 101 8.8E-7 T 13-10-2018 IPR006016 UspA CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 Gene3D G3DSA:3.40.50.300 60 284 1.4E-43 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 Hamap MF_01498 DNA repair protein RadA [radA]. 21 452 42.74 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 SMART SM00382 87 240 8.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 447 3.6E-185 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 Pfam PF13481 AAA domain 65 218 3.0E-15 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 SUPERFAMILY SSF54211 251 451 4.93E-42 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 PRINTS PR01874 DNA repair protein radA signature 244 270 6.8E-88 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 PRINTS PR01874 DNA repair protein radA signature 318 341 6.8E-88 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 PRINTS PR01874 DNA repair protein radA signature 120 137 6.8E-88 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 PRINTS PR01874 DNA repair protein radA signature 209 237 6.8E-88 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 PRINTS PR01874 DNA repair protein radA signature 10 34 6.8E-88 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 PRINTS PR01874 DNA repair protein radA signature 79 107 6.8E-88 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 PRINTS PR01874 DNA repair protein radA signature 170 194 6.8E-88 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 Gene3D G3DSA:3.30.230.10 326 453 4.6E-21 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 Pfam PF13541 Subunit ChlI of Mg-chelatase 341 424 1.2E-10 T 13-10-2018 CLOST_0161 b7f34e8e9df8ee8aedb585916ac8dcfc 453 SUPERFAMILY SSF52540 66 288 2.18E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2378 e9779836e923c52c904076246f9470b1 468 Gene3D G3DSA:3.65.10.10 48 452 1.2E-129 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 CLOST_2378 e9779836e923c52c904076246f9470b1 468 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 49 459 1.2E-120 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CLOST_2378 e9779836e923c52c904076246f9470b1 468 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 44 453 9.5E-108 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOST_2378 e9779836e923c52c904076246f9470b1 468 PIRSF PIRSF000505 35 464 1.1E-135 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CLOST_2378 e9779836e923c52c904076246f9470b1 468 Gene3D G3DSA:3.65.10.10 57 272 1.2E-129 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 CLOST_2378 e9779836e923c52c904076246f9470b1 468 SUPERFAMILY SSF55205 38 461 1.31E-112 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CLOST_2378 e9779836e923c52c904076246f9470b1 468 ProSitePatterns PS00885 EPSP synthase signature 2. 371 389 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CLOST_2378 e9779836e923c52c904076246f9470b1 468 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 45 460 32.129 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CLOST_0282 6c0b905ebe5c0d1ebe82008cf0c2ffbf 348 SUPERFAMILY SSF52733 6 347 2.35E-105 T 13-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 CLOST_0282 6c0b905ebe5c0d1ebe82008cf0c2ffbf 348 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 14 345 5.6E-119 T 13-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 CLOST_0282 6c0b905ebe5c0d1ebe82008cf0c2ffbf 348 Pfam PF02277 Phosphoribosyltransferase 11 345 3.7E-119 T 13-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 CLOST_0282 6c0b905ebe5c0d1ebe82008cf0c2ffbf 348 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 13 348 32.38 T 13-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 CLOST_0282 6c0b905ebe5c0d1ebe82008cf0c2ffbf 348 Gene3D G3DSA:1.10.1610.10 11 338 3.0E-126 T 13-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 CLOST_0282 6c0b905ebe5c0d1ebe82008cf0c2ffbf 348 Gene3D G3DSA:3.40.50.10210 57 329 3.0E-126 T 13-10-2018 CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 SMART SM00267 475 652 3.3E-55 T 13-10-2018 IPR000160 GGDEF domain CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 Gene3D G3DSA:3.30.450.20 333 467 1.7E-12 T 13-10-2018 CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 SMART SM00091 221 288 0.0046 T 13-10-2018 IPR000014 PAS domain CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 SMART SM00091 346 414 60.0 T 13-10-2018 IPR000014 PAS domain CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 Gene3D G3DSA:3.30.70.270 473 650 5.8E-55 T 13-10-2018 CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 343 467 1.4E-8 T 13-10-2018 IPR000014 PAS domain CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 222 341 1.0E-9 T 13-10-2018 IPR000014 PAS domain CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 SUPERFAMILY SSF55073 492 650 5.49E-47 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 Gene3D G3DSA:3.30.450.20 214 332 1.5E-16 T 13-10-2018 CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 SUPERFAMILY SSF55785 331 460 9.25E-12 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 SUPERFAMILY SSF55785 215 332 1.06E-12 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 Pfam PF13426 PAS domain 240 333 1.0E-8 T 13-10-2018 IPR000014 PAS domain CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 Pfam PF13426 PAS domain 363 461 0.014 T 13-10-2018 IPR000014 PAS domain CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 484 650 3.7E-53 T 13-10-2018 IPR000160 GGDEF domain CLOST_0690 7db883989bb2f7a9f78add7693c76a3a 652 Pfam PF00990 Diguanylate cyclase, GGDEF domain 488 647 3.1E-50 T 13-10-2018 IPR000160 GGDEF domain CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 5 521 1.1E-64 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 Pfam PF01514 Secretory protein of YscJ/FliF family 30 220 4.8E-52 T 13-10-2018 IPR006182 Secretory protein YscJ/FliF CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 Gene3D G3DSA:3.30.300.30 121 217 2.9E-11 T 13-10-2018 CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 PRINTS PR01009 Flagellar M-ring protein signature 151 165 6.3E-13 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 PRINTS PR01009 Flagellar M-ring protein signature 348 372 6.3E-13 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 PRINTS PR01009 Flagellar M-ring protein signature 267 285 6.3E-13 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 PRINTS PR01009 Flagellar M-ring protein signature 196 214 6.3E-13 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 Pfam PF08345 Flagellar M-ring protein C-terminal 254 405 3.4E-26 T 13-10-2018 IPR013556 Flagellar M-ring C-terminal CLOST_1741 56c29d2a2881e935be496e4582df00e8 521 PIRSF PIRSF004862 2 521 3.1E-98 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CLOST_2314 1d098565d0dfd100940c168f72f58185 203 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 4 202 3.2E-43 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2314 1d098565d0dfd100940c168f72f58185 203 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 2 203 19.158 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2314 1d098565d0dfd100940c168f72f58185 203 Pfam PF01813 ATP synthase subunit D 11 200 5.9E-50 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_1206 a2b41ec47d4cc470a7600c65eb70bedb 265 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 222 235 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CLOST_1206 a2b41ec47d4cc470a7600c65eb70bedb 265 SUPERFAMILY SSF53613 5 264 1.71E-50 T 13-10-2018 IPR029056 Ribokinase-like CLOST_1206 a2b41ec47d4cc470a7600c65eb70bedb 265 Gene3D G3DSA:3.40.1190.20 1 265 3.1E-46 T 13-10-2018 IPR029056 Ribokinase-like CLOST_1206 a2b41ec47d4cc470a7600c65eb70bedb 265 Pfam PF00294 pfkB family carbohydrate kinase 19 264 2.2E-39 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 Gene3D G3DSA:3.30.420.40 142 337 4.5E-163 T 13-10-2018 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 184 201 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 PIRSF PIRSF036458 6 361 1.8E-171 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 PRINTS PR00471 Acetate kinase family signature 302 318 2.8E-17 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 PRINTS PR00471 Acetate kinase family signature 10 21 2.8E-17 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 PRINTS PR00471 Acetate kinase family signature 184 205 2.8E-17 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 PRINTS PR00471 Acetate kinase family signature 279 292 2.8E-17 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 Gene3D G3DSA:3.30.420.40 9 360 4.5E-163 T 13-10-2018 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 SUPERFAMILY SSF53067 8 177 1.72E-70 T 13-10-2018 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 Pfam PF00871 Acetokinase family 9 355 2.3E-78 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 SUPERFAMILY SSF53067 129 352 3.22E-53 T 13-10-2018 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 Hamap MF_00542 Probable butyrate kinase [buk]. 1 362 170.792 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 9 358 1.4E-174 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0488 1b085c06f3aec97aa603f1cdbef22fc7 362 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 10 21 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_2110 64b2d3b52b26905e833592d98dbb43ca 399 Gene3D G3DSA:3.20.20.190 151 395 1.6E-22 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 CLOST_2110 64b2d3b52b26905e833592d98dbb43ca 399 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 170 391 2.9E-7 T 13-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CLOST_2110 64b2d3b52b26905e833592d98dbb43ca 399 SUPERFAMILY SSF51695 171 391 1.75E-16 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 CLOST_1692 02841ad43ff52d1b9a377c188de7af8e 91 SUPERFAMILY SSF64376 4 88 3.4E-29 T 13-10-2018 IPR035931 YlxR-like superfamily CLOST_1692 02841ad43ff52d1b9a377c188de7af8e 91 Gene3D G3DSA:3.30.1230.10 1 91 3.6E-37 T 13-10-2018 IPR035931 YlxR-like superfamily CLOST_1692 02841ad43ff52d1b9a377c188de7af8e 91 Pfam PF04296 Protein of unknown function (DUF448) 9 82 2.8E-31 T 13-10-2018 IPR007393 Domain of unknown function DUF448 CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 54 120 2.8E-31 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 48 7.5E-20 T 13-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 120 5.4E-48 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 Gene3D G3DSA:1.20.5.710 1 50 7.4E-21 T 13-10-2018 CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 SUPERFAMILY SSF48300 1 56 2.49E-16 T 13-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 Gene3D G3DSA:3.30.1390.10 51 120 8.8E-32 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 120 25.356 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 SUPERFAMILY SSF54736 49 120 1.55E-25 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CLOST_2212 326c2db6ae7f5379094441f50877bd38 120 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 120 8.0E-21 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 Gene3D G3DSA:1.10.8.60 659 752 6.2E-28 T 13-10-2018 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 Gene3D G3DSA:3.40.50.300 441 657 3.6E-84 T 13-10-2018 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 Gene3D G3DSA:3.40.50.300 108 303 6.1E-66 T 13-10-2018 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 SMART SM01086 659 748 1.2E-30 T 13-10-2018 IPR019489 Clp ATPase, C-terminal CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 Gene3D G3DSA:4.10.860.10 368 420 4.3E-35 T 13-10-2018 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 522 540 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 SUPERFAMILY SSF52540 121 385 1.22E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 SUPERFAMILY SSF52540 438 736 4.27E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 Pfam PF07724 AAA domain (Cdc48 subfamily) 488 653 1.4E-53 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 Gene3D G3DSA:1.10.8.60 306 432 4.3E-35 T 13-10-2018 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 492 510 2.0E-38 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 537 555 2.0E-38 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 566 584 2.0E-38 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 613 2.0E-38 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 SMART SM00382 488 660 8.4E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 SMART SM00382 159 304 4.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 164 294 5.0E-11 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_0173 4917924eb2539d0dcfdeecd54e55187b 753 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 659 737 1.3E-26 T 13-10-2018 IPR019489 Clp ATPase, C-terminal CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 Pfam PF01470 Pyroglutamyl peptidase 2 199 7.1E-88 T 13-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 13-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 199 38.003 T 13-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 PIRSF PIRSF015592 1 211 1.5E-84 T 13-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 211 1.8E-79 T 13-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 Gene3D G3DSA:3.40.630.20 1 213 2.8E-80 T 13-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 SUPERFAMILY SSF53182 2 212 3.4E-73 T 13-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 5.4E-48 T 13-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 5.4E-48 T 13-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 5.4E-48 T 13-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 5.4E-48 T 13-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CLOST_0120 decf89a75d026599771a7e0c67afbdcb 213 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 5.4E-48 T 13-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CLOST_0552 55c92e819afee243cdf38a27fa0a5478 444 Gene3D G3DSA:3.30.460.10 4 145 1.1E-49 T 13-10-2018 CLOST_0552 55c92e819afee243cdf38a27fa0a5478 444 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 173 233 1.5E-22 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CLOST_0552 55c92e819afee243cdf38a27fa0a5478 444 SUPERFAMILY SSF81891 144 442 6.41E-60 T 13-10-2018 CLOST_0552 55c92e819afee243cdf38a27fa0a5478 444 Pfam PF01743 Poly A polymerase head domain 24 146 8.5E-37 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CLOST_0552 55c92e819afee243cdf38a27fa0a5478 444 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 296 433 3.2E-11 T 13-10-2018 IPR032810 CCA-adding enzyme, C-terminal CLOST_0552 55c92e819afee243cdf38a27fa0a5478 444 SUPERFAMILY SSF81301 7 143 3.92E-40 T 13-10-2018 CLOST_0552 55c92e819afee243cdf38a27fa0a5478 444 Gene3D G3DSA:1.10.3090.10 146 433 1.9E-63 T 13-10-2018 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 SUPERFAMILY SSF53613 5 259 7.04E-55 T 13-10-2018 IPR029056 Ribokinase-like CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 Pfam PF02110 Hydroxyethylthiazole kinase family 9 255 5.4E-78 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 PIRSF PIRSF000513 3 267 1.0E-85 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 9 259 3.9E-82 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 11 260 32.004 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 87 104 2.0E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 162 179 2.0E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 118 132 2.0E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 30 51 2.0E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 17 24 2.0E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 61 69 2.0E-38 T 13-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2009 cbd78a7efbbc395d23dbf957633c3ce0 273 Gene3D G3DSA:3.40.1190.20 1 267 1.6E-92 T 13-10-2018 IPR029056 Ribokinase-like CLOST_1398 3f1a125d44f83e2db273d196b4eb2169 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 4 192 7.0E-87 T 13-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 CLOST_1398 3f1a125d44f83e2db273d196b4eb2169 193 Hamap MF_00459 Ion-translocating oxidoreductase complex subunit A [rsxA]. 3 192 26.805 T 13-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 CLOST_1398 3f1a125d44f83e2db273d196b4eb2169 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 191 1.9E-64 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 CLOST_1398 3f1a125d44f83e2db273d196b4eb2169 193 PIRSF PIRSF006102 1 193 1.3E-60 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 CLOST_1703 7ee2fe723947ef066a86544eeeab63aa 237 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 235 3.4E-100 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CLOST_1703 7ee2fe723947ef066a86544eeeab63aa 237 Gene3D G3DSA:3.40.1160.10 2 237 2.5E-81 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_1703 7ee2fe723947ef066a86544eeeab63aa 237 PIRSF PIRSF005650 1 237 2.3E-97 T 13-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CLOST_1703 7ee2fe723947ef066a86544eeeab63aa 237 PRINTS PR00474 Glutamate 5-kinase family signature 6 20 5.8E-5 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CLOST_1703 7ee2fe723947ef066a86544eeeab63aa 237 PRINTS PR00474 Glutamate 5-kinase family signature 139 166 5.8E-5 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CLOST_1703 7ee2fe723947ef066a86544eeeab63aa 237 Pfam PF00696 Amino acid kinase family 7 214 7.6E-30 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 CLOST_1703 7ee2fe723947ef066a86544eeeab63aa 237 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 235 45.221 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CLOST_1703 7ee2fe723947ef066a86544eeeab63aa 237 SUPERFAMILY SSF53633 5 235 1.96E-73 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_2111 34f46add56ea177d2b1ac2752106dd32 120 PIRSF PIRSF033490 5 117 2.3E-37 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CLOST_2111 34f46add56ea177d2b1ac2752106dd32 120 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 8 114 4.6E-33 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CLOST_2111 34f46add56ea177d2b1ac2752106dd32 120 Gene3D G3DSA:2.30.30.110 1 119 7.1E-51 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CLOST_2111 34f46add56ea177d2b1ac2752106dd32 120 SUPERFAMILY SSF50118 6 117 2.78E-41 T 13-10-2018 CLOST_2269 c4699ba8c5536ba948633c9048ad302c 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 324 6.2E-42 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_2269 c4699ba8c5536ba948633c9048ad302c 328 Gene3D G3DSA:1.10.3720.10 89 321 6.0E-25 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2269 c4699ba8c5536ba948633c9048ad302c 328 SUPERFAMILY SSF161098 96 313 4.06E-20 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 Pfam PF13167 GTP-binding GTPase N-terminal 32 120 3.9E-32 T 13-10-2018 IPR025121 GTPase HflX, N-terminal CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 13 370 2.7E-138 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 SUPERFAMILY SSF52540 205 372 8.18E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 283 301 1.7E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 208 228 1.7E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 Pfam PF16360 GTP-binding GTPase Middle Region 122 200 3.4E-31 T 13-10-2018 IPR032305 GTP-binding protein, middle domain CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 Gene3D G3DSA:3.40.50.11060 23 146 1.4E-39 T 13-10-2018 CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 Gene3D G3DSA:3.40.50.300 205 378 6.0E-40 T 13-10-2018 CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 Hamap MF_00900 GTPase HflX [hflX]. 35 401 48.068 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 Pfam PF01926 50S ribosome-binding GTPase 208 334 3.6E-18 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1327 d676b6047c672b21646e0209cd7ca528 432 PIRSF PIRSF006809 3 431 5.1E-145 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 Pfam PF00330 Aconitase family (aconitate hydratase) 8 411 3.5E-99 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 PRINTS PR00415 Aconitase family signature 103 111 4.4E-20 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 PRINTS PR00415 Aconitase family signature 352 365 4.4E-20 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 PRINTS PR00415 Aconitase family signature 128 143 4.4E-20 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 PRINTS PR00415 Aconitase family signature 190 203 4.4E-20 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 PRINTS PR00415 Aconitase family signature 114 127 4.4E-20 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 PRINTS PR00415 Aconitase family signature 204 217 4.4E-20 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 Gene3D G3DSA:3.30.499.20 4 270 2.3E-100 T 13-10-2018 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 TIGRFAM TIGR02083 LEU2: 3-isopropylmalate dehydratase, large subunit 3 418 4.9E-218 T 13-10-2018 IPR011823 3-isopropylmalate dehydratase, large subunit, bacteria GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 417 6.2E-159 T 13-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 419 48.485 T 13-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 ProSitePatterns PS00450 Aconitase family signature 1. 292 308 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 Gene3D G3DSA:3.30.499.10 273 419 2.7E-55 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 416 7.1E-171 T 13-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 CLOST_0415 2f03a734a58d617e2771ef923b2ef1fe 422 SUPERFAMILY SSF53732 1 419 3.92E-147 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 11 179 1.7E-61 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 Pfam PF02357 Transcription termination factor nusG 10 112 2.8E-28 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 SUPERFAMILY SSF82679 9 112 3.79E-37 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 Gene3D G3DSA:3.30.70.940 3 120 5.9E-44 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 SUPERFAMILY SSF50104 124 179 5.16E-17 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 8 179 24.154 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 SMART SM00739 125 152 6.4E-4 T 13-10-2018 IPR005824 KOW CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 Gene3D G3DSA:2.30.30.30 121 179 3.0E-23 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 SMART SM00738 8 116 5.4E-43 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 ProSitePatterns PS01014 Transcription termination factor nusG signature. 162 171 - T 13-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 PRINTS PR00338 Transcription termination factor NUSG signature 137 152 8.8E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 PRINTS PR00338 Transcription termination factor NUSG signature 155 171 8.8E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CLOST_2216 a32a9d02df326b71ab427a551e7229a3 180 PRINTS PR00338 Transcription termination factor NUSG signature 63 75 8.8E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 SMART SM00525 184 204 0.0029 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 Gene3D G3DSA:1.10.1670.10 9 201 8.5E-80 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 TIGRFAM TIGR01083 nth: endonuclease III 3 192 1.2E-85 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 SMART SM00478 36 183 2.9E-64 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 SUPERFAMILY SSF48150 5 206 9.89E-74 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 Gene3D G3DSA:1.10.340.30 19 130 8.5E-80 T 13-10-2018 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 Pfam PF00633 Helix-hairpin-helix motif 98 125 1.4E-8 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 32 166 2.1E-23 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 PIRSF PIRSF001435 1 209 4.5E-59 T 13-10-2018 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 Hamap MF_00942 Endonuclease III [nth]. 1 207 39.176 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CLOST_1099 2d7a3532089f95cb939f972972fc81c0 209 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 185 201 2.3E-4 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CLOST_2341 7a4af516c1b64908f83531ec7fbf9c68 366 Gene3D G3DSA:3.40.640.10 1 241 8.8E-96 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_2341 7a4af516c1b64908f83531ec7fbf9c68 366 Gene3D G3DSA:3.90.1150.10 243 366 6.7E-28 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_2341 7a4af516c1b64908f83531ec7fbf9c68 366 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 361 8.4E-117 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_2341 7a4af516c1b64908f83531ec7fbf9c68 366 SUPERFAMILY SSF53383 2 365 1.02E-115 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_2341 7a4af516c1b64908f83531ec7fbf9c68 366 PIRSF PIRSF000390 1 366 3.1E-112 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_1365 33903693bd2f9b577492e32cdf048ee3 221 SUPERFAMILY SSF143548 19 138 9.94E-30 T 13-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 CLOST_1365 33903693bd2f9b577492e32cdf048ee3 221 Pfam PF01842 ACT domain 150 209 1.3E-9 T 13-10-2018 IPR002912 ACT domain CLOST_1365 33903693bd2f9b577492e32cdf048ee3 221 PIRSF PIRSF036692 1 221 7.7E-86 T 13-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CLOST_1365 33903693bd2f9b577492e32cdf048ee3 221 Gene3D G3DSA:3.30.70.260 148 219 6.8E-14 T 13-10-2018 CLOST_1365 33903693bd2f9b577492e32cdf048ee3 221 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 204 1.4E-69 T 13-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CLOST_1365 33903693bd2f9b577492e32cdf048ee3 221 SUPERFAMILY SSF55021 137 218 6.11E-16 T 13-10-2018 CLOST_1365 33903693bd2f9b577492e32cdf048ee3 221 Pfam PF03315 Serine dehydratase beta chain 5 132 3.5E-15 T 13-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CLOST_1365 33903693bd2f9b577492e32cdf048ee3 221 Gene3D G3DSA:3.30.1330.90 13 137 1.1E-21 T 13-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 SUPERFAMILY SSF50331 238 344 5.38E-12 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 Gene3D G3DSA:3.40.50.300 5 223 2.1E-69 T 13-10-2018 CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 36 324 2.5E-117 T 13-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 Pfam PF00005 ABC transporter 21 163 2.6E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 Gene3D G3DSA:2.40.50.140 281 336 2.8E-11 T 13-10-2018 CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 SUPERFAMILY SSF52540 5 246 9.93E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 Gene3D G3DSA:2.40.50.940 224 343 2.8E-11 T 13-10-2018 CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 Pfam PF08402 TOBE domain 274 344 6.5E-7 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 CLOST_1748 f4477d4f07f3c002c7556d979144e577 351 SMART SM00382 30 213 5.5E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0253 a7b6a101b3cd937f16ec135774d96062 254 Pfam PF01923 Cobalamin adenosyltransferase 94 248 5.0E-14 T 13-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CLOST_0253 a7b6a101b3cd937f16ec135774d96062 254 SUPERFAMILY SSF89028 95 251 2.55E-9 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CLOST_0253 a7b6a101b3cd937f16ec135774d96062 254 PIRSF PIRSF012294 1 254 6.7E-76 T 13-10-2018 IPR009194 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT-type GO:0005524|GO:0006580|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 CLOST_0253 a7b6a101b3cd937f16ec135774d96062 254 Gene3D G3DSA:1.20.1200.10 94 254 2.3E-9 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CLOST_0560 81ae9ae886c77f898a15b526fbf88307 873 Gene3D G3DSA:3.40.50.410 395 619 1.5E-27 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily CLOST_0560 81ae9ae886c77f898a15b526fbf88307 873 Pfam PF01345 Domain of unknown function DUF11 211 298 1.2E-9 T 13-10-2018 IPR001434 Domain of unknown function DUF11 CLOST_0560 81ae9ae886c77f898a15b526fbf88307 873 Pfam PF13519 von Willebrand factor type A domain 402 521 3.5E-14 T 13-10-2018 IPR002035 von Willebrand factor, type A CLOST_0560 81ae9ae886c77f898a15b526fbf88307 873 SUPERFAMILY SSF53300 398 567 8.62E-21 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily CLOST_0560 81ae9ae886c77f898a15b526fbf88307 873 SMART SM00327 399 598 2.0E-16 T 13-10-2018 IPR002035 von Willebrand factor, type A CLOST_0560 81ae9ae886c77f898a15b526fbf88307 873 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 213 248 1.3E-8 T 13-10-2018 IPR001434 Domain of unknown function DUF11 CLOST_0280 a2323532a76273e826eed16ee7b871ba 69 Gene3D G3DSA:3.30.70.100 1 65 3.5E-20 T 13-10-2018 CLOST_0280 a2323532a76273e826eed16ee7b871ba 69 SUPERFAMILY SSF55008 1 66 2.62E-17 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 CLOST_0280 a2323532a76273e826eed16ee7b871ba 69 PRINTS PR00944 Copper ion binding protein signature 14 27 4.4E-7 T 13-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CLOST_0280 a2323532a76273e826eed16ee7b871ba 69 PRINTS PR00944 Copper ion binding protein signature 40 52 4.4E-7 T 13-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CLOST_0280 a2323532a76273e826eed16ee7b871ba 69 PRINTS PR00944 Copper ion binding protein signature 2 14 4.4E-7 T 13-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CLOST_0280 a2323532a76273e826eed16ee7b871ba 69 PRINTS PR00944 Copper ion binding protein signature 52 65 4.4E-7 T 13-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CLOST_0280 a2323532a76273e826eed16ee7b871ba 69 PRINTS PR00944 Copper ion binding protein signature 27 40 4.4E-7 T 13-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CLOST_0280 a2323532a76273e826eed16ee7b871ba 69 Pfam PF00403 Heavy-metal-associated domain 4 64 3.4E-17 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOST_1835 566f5dd65e2c9774b1bf7f841afab283 235 Gene3D G3DSA:3.40.50.720 1 235 2.8E-76 T 13-10-2018 CLOST_1835 566f5dd65e2c9774b1bf7f841afab283 235 Pfam PF00899 ThiF family 8 230 1.8E-36 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CLOST_1835 566f5dd65e2c9774b1bf7f841afab283 235 SUPERFAMILY SSF69572 5 230 3.53E-54 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 CLOST_1463 11cf1a6cc6366604b0d0f2c76df4c1ed 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 7.4E-42 T 13-10-2018 IPR007347 Sporulation stage V, protein S CLOST_1463 11cf1a6cc6366604b0d0f2c76df4c1ed 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 3.0E-38 T 13-10-2018 IPR007347 Sporulation stage V, protein S CLOST_1463 11cf1a6cc6366604b0d0f2c76df4c1ed 86 Gene3D G3DSA:3.30.110.20 1 86 2.5E-37 T 13-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 CLOST_2254 7631e6f296898ca6692b2745c5ee5f93 572 Gene3D G3DSA:3.90.76.10 97 228 6.6E-122 T 13-10-2018 CLOST_2254 7631e6f296898ca6692b2745c5ee5f93 572 SUPERFAMILY SSF53850 63 566 6.7E-119 T 13-10-2018 CLOST_2254 7631e6f296898ca6692b2745c5ee5f93 572 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 117 485 2.3E-84 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain CLOST_2254 7631e6f296898ca6692b2745c5ee5f93 572 PIRSF PIRSF002741 3 572 5.2E-105 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CLOST_2254 7631e6f296898ca6692b2745c5ee5f93 572 Gene3D G3DSA:3.40.190.10 82 553 6.6E-122 T 13-10-2018 CLOST_2254 7631e6f296898ca6692b2745c5ee5f93 572 Gene3D G3DSA:3.10.105.10 322 539 6.6E-122 T 13-10-2018 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 218 5.3E-45 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 Gene3D G3DSA:3.10.290.10 1 56 8.5E-21 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 Pfam PF00849 RNA pseudouridylate synthase 62 189 1.4E-16 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 Gene3D G3DSA:3.30.70.580 64 223 5.4E-55 T 13-10-2018 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 Pfam PF01479 S4 domain 1 46 3.2E-11 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 SUPERFAMILY SSF55120 58 225 1.55E-41 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 SUPERFAMILY SSF55174 1 89 3.53E-17 T 13-10-2018 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 Gene3D G3DSA:3.30.70.1560 128 201 5.4E-55 T 13-10-2018 CLOST_1477 4c6e86ee6336f427d97bb235469468a0 235 SMART SM00363 1 59 4.1E-11 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1391 99f9fe83d5b9cb1d0246587d7a7fc1e1 213 Gene3D G3DSA:2.160.20.70 100 213 1.6E-38 T 13-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 CLOST_1391 99f9fe83d5b9cb1d0246587d7a7fc1e1 213 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 7 210 20.595 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CLOST_1391 99f9fe83d5b9cb1d0246587d7a7fc1e1 213 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 106 207 1.4E-30 T 13-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CLOST_1391 99f9fe83d5b9cb1d0246587d7a7fc1e1 213 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 8 207 3.9E-33 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CLOST_1391 99f9fe83d5b9cb1d0246587d7a7fc1e1 213 SUPERFAMILY SSF63848 104 209 1.44E-31 T 13-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 CLOST_1977 db97df34efd69d426831fca2b9eeee9f 210 SUPERFAMILY SSF102198 1 209 2.88E-65 T 13-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CLOST_1977 db97df34efd69d426831fca2b9eeee9f 210 Gene3D G3DSA:3.50.30.50 1 209 2.5E-65 T 13-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CLOST_1977 db97df34efd69d426831fca2b9eeee9f 210 Pfam PF04199 Putative cyclase 4 153 3.1E-31 T 13-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CLOST_0309 5c73643e282649d58de4d0e5accdab8d 470 Gene3D G3DSA:1.10.1740.180 90 275 3.3E-35 T 13-10-2018 CLOST_0309 5c73643e282649d58de4d0e5accdab8d 470 Gene3D G3DSA:1.10.10.2090 134 251 3.3E-35 T 13-10-2018 CLOST_0309 5c73643e282649d58de4d0e5accdab8d 470 Pfam PF13020 Domain of unknown function (DUF3883) 362 429 3.0E-14 T 13-10-2018 IPR024975 Domain of unknown function DUF3883 CLOST_0309 5c73643e282649d58de4d0e5accdab8d 470 Pfam PF11564 Restriction endonuclease BpuJI - N terminal 2 274 4.8E-127 T 13-10-2018 IPR021108 Restriction endonuclease, type II, BpuJI, N-terminal CLOST_0221 dff7042f1df26d94a4f4325a58ebf593 269 SUPERFAMILY SSF56300 43 268 8.65E-35 T 13-10-2018 CLOST_0221 dff7042f1df26d94a4f4325a58ebf593 269 Pfam PF00149 Calcineurin-like phosphoesterase 43 207 3.9E-12 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CLOST_0221 dff7042f1df26d94a4f4325a58ebf593 269 Gene3D G3DSA:3.60.21.10 41 223 4.8E-27 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 SUPERFAMILY SSF88946 28 121 1.7E-21 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 76 89 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 SUPERFAMILY SSF46894 165 221 4.08E-9 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 Gene3D G3DSA:1.10.10.10 144 229 2.0E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 Gene3D G3DSA:1.10.10.10 71 143 4.4E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 34 226 1.4E-91 T 13-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 225 8.5E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 PIRSF PIRSF002939 4 229 8.8E-93 T 13-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 CLOST_2220 c5ad3c83d8489c2ec65e8f044eb25101 229 Pfam PF04542 Sigma-70 region 2 53 121 7.7E-13 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_2448 de2f7acb388bf7971593d9ccd1116ab0 197 Pfam PF01965 DJ-1/PfpI family 2 177 2.4E-25 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 CLOST_2448 de2f7acb388bf7971593d9ccd1116ab0 197 SUPERFAMILY SSF52317 1 191 1.5E-36 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_2448 de2f7acb388bf7971593d9ccd1116ab0 197 Gene3D G3DSA:3.40.50.880 1 197 1.3E-38 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_2303 2b2ba9cdd13e3330ee85bc6c4e129e31 201 Pfam PF12822 ECF transporter, substrate-specific component 15 191 5.2E-26 T 13-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CLOST_2303 2b2ba9cdd13e3330ee85bc6c4e129e31 201 PIRSF PIRSF037778 9 201 3.2E-47 T 13-10-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CLOST_2303 2b2ba9cdd13e3330ee85bc6c4e129e31 201 Gene3D G3DSA:1.10.1760.20 10 201 2.3E-53 T 13-10-2018 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 198 263 4.3E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 420 1.2E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 Gene3D G3DSA:3.30.565.10 268 427 8.7E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 Gene3D G3DSA:3.30.450.20 72 188 1.4E-16 T 13-10-2018 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 80 195 5.1E-9 T 13-10-2018 IPR000014 PAS domain CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 SUPERFAMILY SSF47384 185 264 1.96E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 SMART SM00387 310 422 3.9E-39 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 SUPERFAMILY SSF55874 253 420 5.89E-46 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 SUPERFAMILY SSF55785 76 189 3.14E-9 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 Gene3D G3DSA:1.10.287.130 189 267 1.5E-21 T 13-10-2018 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 Pfam PF13426 PAS domain 94 190 4.6E-8 T 13-10-2018 IPR000014 PAS domain CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 SMART SM00091 83 149 1.4E-4 T 13-10-2018 IPR000014 PAS domain CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 4.1E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 4.1E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 4.1E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 4.1E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1887 0483204accdeb820b3dbcbf4a27e43f0 427 SMART SM00388 197 264 2.9E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1828 657c90f6db6fac256462aac103f488d0 238 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 177 205 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CLOST_1828 657c90f6db6fac256462aac103f488d0 238 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 8 89 6.7E-32 T 13-10-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CLOST_1828 657c90f6db6fac256462aac103f488d0 238 Gene3D G3DSA:3.30.70.250 5 87 6.8E-31 T 13-10-2018 CLOST_1828 657c90f6db6fac256462aac103f488d0 238 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 5 238 43.831 T 13-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CLOST_1828 657c90f6db6fac256462aac103f488d0 238 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 10 238 4.6E-107 T 13-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CLOST_1828 657c90f6db6fac256462aac103f488d0 238 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 94 122 4.9E-5 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_1828 657c90f6db6fac256462aac103f488d0 238 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 125 159 1.1E-6 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_1828 657c90f6db6fac256462aac103f488d0 238 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 168 203 1.5E-10 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_1828 657c90f6db6fac256462aac103f488d0 238 SUPERFAMILY SSF51161 89 228 5.24E-52 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_1828 657c90f6db6fac256462aac103f488d0 238 Gene3D G3DSA:2.160.10.10 88 238 1.5E-46 T 13-10-2018 CLOST_0398 2b10f797a4b915566812ec852948ec55 356 SUPERFAMILY SSF52242 232 353 1.22E-22 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0398 2b10f797a4b915566812ec852948ec55 356 Pfam PF02310 B12 binding domain 242 330 7.8E-18 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0398 2b10f797a4b915566812ec852948ec55 356 Gene3D G3DSA:1.10.1240.10 149 226 1.8E-13 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0398 2b10f797a4b915566812ec852948ec55 356 Gene3D G3DSA:3.40.50.280 230 356 8.7E-30 T 13-10-2018 CLOST_0398 2b10f797a4b915566812ec852948ec55 356 Pfam PF02607 B12 binding domain 152 223 1.1E-11 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_2535 80bca61f71dbeca2f90d4fdd0e1389ca 406 Pfam PF13411 MerR HTH family regulatory protein 1 65 5.7E-11 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_2535 80bca61f71dbeca2f90d4fdd0e1389ca 406 SUPERFAMILY SSF53335 183 332 2.5E-14 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_2535 80bca61f71dbeca2f90d4fdd0e1389ca 406 Gene3D G3DSA:3.40.50.150 134 346 1.1E-12 T 13-10-2018 CLOST_2535 80bca61f71dbeca2f90d4fdd0e1389ca 406 Gene3D G3DSA:1.10.1660.10 1 126 4.5E-19 T 13-10-2018 CLOST_2535 80bca61f71dbeca2f90d4fdd0e1389ca 406 SMART SM00422 1 68 5.7E-6 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_2535 80bca61f71dbeca2f90d4fdd0e1389ca 406 SUPERFAMILY SSF46955 1 115 1.21E-14 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 SUPERFAMILY SSF51905 1 313 5.67E-63 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PIRSF PIRSF000350 1 451 4.9E-87 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 2 455 9.9E-167 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 440 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 413 2.0E-68 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 5.8E-37 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 5.8E-37 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 5.8E-37 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 5.8E-37 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 5.8E-37 T 13-10-2018 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 445 9.0E-30 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 Gene3D G3DSA:3.50.50.60 152 270 9.9E-115 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 319 5.2E-72 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 Gene3D G3DSA:3.30.390.30 337 456 2.5E-39 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 SUPERFAMILY SSF55424 335 455 7.56E-36 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_1166 754dacd1daeca7533b2bdda3d7364bdd 457 Gene3D G3DSA:3.50.50.60 3 323 9.9E-115 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0320 66c6a61460f94cc712f699749409ed55 185 Gene3D G3DSA:1.20.1440.20 14 185 1.9E-69 T 13-10-2018 IPR023353 LemA-like domain superfamily CLOST_0320 66c6a61460f94cc712f699749409ed55 185 SUPERFAMILY SSF140478 25 172 4.05E-61 T 13-10-2018 IPR023353 LemA-like domain superfamily CLOST_0320 66c6a61460f94cc712f699749409ed55 185 Pfam PF04011 LemA family 5 185 1.6E-74 T 13-10-2018 IPR007156 LemA CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 SUPERFAMILY SSF50331 237 368 6.32E-26 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 Gene3D G3DSA:2.40.50.100 240 367 4.7E-26 T 13-10-2018 CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 SMART SM00382 29 212 1.4E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 Pfam PF08402 TOBE domain 285 360 3.2E-5 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 Gene3D G3DSA:3.40.50.300 1 239 2.2E-74 T 13-10-2018 CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 Gene3D G3DSA:2.40.50.140 288 353 4.7E-26 T 13-10-2018 CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 SUPERFAMILY SSF52540 4 245 1.82E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1216 c4f675ff70b740edd813fab40a3b145a 371 Pfam PF00005 ABC transporter 21 162 3.4E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0026 301ad903aa0085d4a771d27111f6ae5a 511 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 507 7.3E-201 T 13-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0026 301ad903aa0085d4a771d27111f6ae5a 511 Gene3D G3DSA:1.20.200.10 198 511 1.0E-118 T 13-10-2018 CLOST_0026 301ad903aa0085d4a771d27111f6ae5a 511 SUPERFAMILY SSF48557 3 499 1.33E-191 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 CLOST_0026 301ad903aa0085d4a771d27111f6ae5a 511 Pfam PF00221 Aromatic amino acid lyase 11 469 3.0E-197 T 13-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CLOST_0026 301ad903aa0085d4a771d27111f6ae5a 511 Gene3D G3DSA:1.10.275.10 1 197 7.9E-72 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal CLOST_0026 301ad903aa0085d4a771d27111f6ae5a 511 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 13-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CLOST_0026 301ad903aa0085d4a771d27111f6ae5a 511 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 505 45.684 T 13-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0117 d7ecbc55b5b8eeef2d7cd551dfe7566f 173 Pfam PF06149 Protein of unknown function (DUF969) 2 163 2.4E-73 T 13-10-2018 IPR010374 Protein of unknown function DUF969 CLOST_2095 f663eabea4b4fba9fb810d0b71ca1ea1 215 SUPERFAMILY SSF52540 4 215 1.19E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2095 f663eabea4b4fba9fb810d0b71ca1ea1 215 Pfam PF00005 ABC transporter 21 170 6.2E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2095 f663eabea4b4fba9fb810d0b71ca1ea1 215 SMART SM00382 30 209 5.1E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2095 f663eabea4b4fba9fb810d0b71ca1ea1 215 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2095 f663eabea4b4fba9fb810d0b71ca1ea1 215 Gene3D G3DSA:3.40.50.300 2 215 2.5E-60 T 13-10-2018 CLOST_1859 1b4217f9a1bf1563c383c3a0a8804a68 84 SUPERFAMILY SSF63562 1 71 1.57E-20 T 13-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CLOST_1859 1b4217f9a1bf1563c383c3a0a8804a68 84 SMART SM01409 8 60 9.6E-12 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CLOST_1859 1b4217f9a1bf1563c383c3a0a8804a68 84 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 14.366 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_1859 1b4217f9a1bf1563c383c3a0a8804a68 84 Gene3D G3DSA:3.90.940.10 1 84 1.4E-19 T 13-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CLOST_1859 1b4217f9a1bf1563c383c3a0a8804a68 84 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 2.3E-10 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_1859 1b4217f9a1bf1563c383c3a0a8804a68 84 Pfam PF01192 RNA polymerase Rpb6 8 60 2.7E-13 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 Gene3D G3DSA:3.30.450.20 3 139 2.0E-17 T 13-10-2018 CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 SUPERFAMILY SSF109604 465 634 5.32E-36 T 13-10-2018 CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 Pfam PF01966 HD domain 477 597 2.2E-20 T 13-10-2018 IPR006674 HD domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 Pfam PF00990 Diguanylate cyclase, GGDEF domain 306 449 1.3E-24 T 13-10-2018 IPR000160 GGDEF domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 SMART SM00267 294 463 6.1E-22 T 13-10-2018 IPR000160 GGDEF domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 SMART SM00471 469 606 1.3E-7 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 301 450 3.7E-25 T 13-10-2018 IPR000160 GGDEF domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 Gene3D G3DSA:3.30.70.270 293 452 1.9E-30 T 13-10-2018 CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 Gene3D G3DSA:1.10.3210.10 453 638 2.0E-66 T 13-10-2018 CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 Pfam PF00989 PAS fold 11 130 5.3E-10 T 13-10-2018 IPR013767 PAS fold GO:0006355 CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 Pfam PF00989 PAS fold 147 255 1.5E-8 T 13-10-2018 IPR013767 PAS fold GO:0006355 CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 52 2.0E-6 T 13-10-2018 IPR000014 PAS domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 263 3.1E-15 T 13-10-2018 IPR000014 PAS domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 SMART SM00091 146 212 3.3E-6 T 13-10-2018 IPR000014 PAS domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 SMART SM00091 8 74 2.2E-5 T 13-10-2018 IPR000014 PAS domain CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 SUPERFAMILY SSF55785 5 128 6.28E-12 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 Gene3D G3DSA:3.30.450.20 140 292 6.6E-20 T 13-10-2018 CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 SUPERFAMILY SSF55785 134 256 2.79E-17 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2264 ad07ff8639170eb2ca3e2e19e5571981 639 SUPERFAMILY SSF55073 310 449 6.98E-25 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 SUPERFAMILY SSF47781 549 626 1.87E-15 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 SUPERFAMILY SSF50249 629 716 3.65E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 SUPERFAMILY SSF158832 1 308 7.32E-103 T 13-10-2018 CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Pfam PF00575 S1 RNA binding domain 643 715 1.2E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Pfam PF16921 Tex protein YqgF-like domain 314 439 1.4E-55 T 13-10-2018 IPR032639 Tex protein, YqgF-like domain CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Gene3D G3DSA:2.40.50.140 631 717 4.3E-29 T 13-10-2018 CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Gene3D G3DSA:3.30.420.140 313 439 4.9E-145 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 SUPERFAMILY SSF53098 310 457 1.52E-48 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 SMART SM00316 644 715 1.9E-27 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Pfam PF09371 Tex-like protein N-terminal domain 7 188 2.3E-63 T 13-10-2018 IPR018974 Tex-like protein, N-terminal CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 SUPERFAMILY SSF47781 458 545 4.56E-27 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Gene3D G3DSA:1.10.3500.10 110 486 4.9E-145 T 13-10-2018 IPR023323 Tex-like domain superfamily CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Pfam PF12836 Helix-hairpin-helix motif 479 543 4.2E-28 T 13-10-2018 CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Gene3D G3DSA:1.10.150.310 487 624 2.7E-46 T 13-10-2018 CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 SMART SM00732 314 412 3.1E-34 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CLOST_2304 b5d4e68623eb87b3c0d122de74ce7485 717 Gene3D G3DSA:1.10.10.650 2 107 3.2E-36 T 13-10-2018 IPR023319 Tex-like protein, HTH domain superfamily CLOST_1055 d48d470c8f6ad607c44d1fcbb0d1af25 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 61 1.2E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_1055 d48d470c8f6ad607c44d1fcbb0d1af25 224 SUPERFAMILY SSF46689 12 76 1.08E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_1055 d48d470c8f6ad607c44d1fcbb0d1af25 224 Gene3D G3DSA:1.10.357.10 11 202 2.4E-14 T 13-10-2018 CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 13-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 4.9E-32 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 SUPERFAMILY SSF55594 3 82 1.05E-28 T 13-10-2018 IPR035895 HPr-like superfamily CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 8.5E-33 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 Gene3D G3DSA:3.30.1340.10 1 87 8.8E-35 T 13-10-2018 IPR035895 HPr-like superfamily CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 13-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.3E-21 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 3.3E-21 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like CLOST_1653 9a1c615fdd180581bc1fe01147cd5b1b 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 3.3E-21 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like CLOST_0158 ce95a82027599b96b959f93d4af2fef7 167 PIRSF PIRSF015034 1 167 1.9E-55 T 13-10-2018 IPR025542 YacH protein CLOST_0158 ce95a82027599b96b959f93d4af2fef7 167 SUPERFAMILY SSF46600 128 164 3.27E-6 T 13-10-2018 IPR036876 UVR domain superfamily CLOST_0158 ce95a82027599b96b959f93d4af2fef7 167 Gene3D G3DSA:4.10.860.10 127 167 1.1E-6 T 13-10-2018 CLOST_0158 ce95a82027599b96b959f93d4af2fef7 167 Pfam PF02151 UvrB/uvrC motif 130 165 5.3E-8 T 13-10-2018 IPR001943 UVR domain GO:0005515 CLOST_0171 ebf51392d3a2b813ff5b273e5640a3f0 340 ProSitePatterns PS00770 Aminotransferases class-IV signature. 220 249 - T 13-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 CLOST_0171 ebf51392d3a2b813ff5b273e5640a3f0 340 SUPERFAMILY SSF56752 3 336 9.68E-103 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 CLOST_0171 ebf51392d3a2b813ff5b273e5640a3f0 340 Pfam PF01063 Amino-transferase class IV 57 293 4.6E-36 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 CLOST_0171 ebf51392d3a2b813ff5b273e5640a3f0 340 Gene3D G3DSA:3.30.470.10 1 160 1.2E-59 T 13-10-2018 CLOST_0171 ebf51392d3a2b813ff5b273e5640a3f0 340 Gene3D G3DSA:3.20.10.10 161 340 3.9E-54 T 13-10-2018 CLOST_0171 ebf51392d3a2b813ff5b273e5640a3f0 340 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 31 339 1.9E-137 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CLOST_0171 ebf51392d3a2b813ff5b273e5640a3f0 340 PIRSF PIRSF006468 1 340 4.4E-120 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CLOST_1349 2141819a86ea948a1446663dac51d68b 133 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 133 21.301 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 CLOST_1349 2141819a86ea948a1446663dac51d68b 133 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 131 3.0E-41 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 CLOST_1349 2141819a86ea948a1446663dac51d68b 133 SUPERFAMILY SSF48013 2 131 1.96E-35 T 13-10-2018 IPR035926 NusB-like superfamily CLOST_1349 2141819a86ea948a1446663dac51d68b 133 Pfam PF01029 NusB family 5 130 6.2E-36 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CLOST_1349 2141819a86ea948a1446663dac51d68b 133 Gene3D G3DSA:1.10.940.10 1 133 3.7E-42 T 13-10-2018 IPR035926 NusB-like superfamily CLOST_0323 e7031b1eaa6f2339b31c5b81a086deca 275 Gene3D G3DSA:3.40.50.300 1 274 4.3E-57 T 13-10-2018 CLOST_0323 e7031b1eaa6f2339b31c5b81a086deca 275 SUPERFAMILY SSF52540 1 271 2.25E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0323 e7031b1eaa6f2339b31c5b81a086deca 275 Pfam PF13614 AAA domain 3 182 1.7E-40 T 13-10-2018 IPR025669 AAA domain CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 SUPERFAMILY SSF101801 300 381 7.98E-23 T 13-10-2018 IPR036429 SpoA-like superfamily CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 SUPERFAMILY SSF103039 25 216 1.31E-47 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 PRINTS PR00956 Flagellar motor switch protein FliN signature 337 350 6.8E-24 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 PRINTS PR00956 Flagellar motor switch protein FliN signature 321 337 6.8E-24 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 PRINTS PR00956 Flagellar motor switch protein FliN signature 304 320 6.8E-24 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 PRINTS PR00956 Flagellar motor switch protein FliN signature 350 365 6.8E-24 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 Gene3D G3DSA:2.30.330.10 292 383 1.1E-32 T 13-10-2018 IPR036429 SpoA-like superfamily CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 301 376 1.8E-30 T 13-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 Gene3D G3DSA:3.40.1550.10 24 223 3.5E-51 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 304 374 9.4E-24 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 Pfam PF04509 CheC-like family 127 163 4.1E-13 T 13-10-2018 IPR007597 CheC-like protein GO:0016787 CLOST_1726 363a7b5e5fa4a47522ac98ab09eb751d 383 Pfam PF04509 CheC-like family 29 65 1.5E-10 T 13-10-2018 IPR007597 CheC-like protein GO:0016787 CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 SMART SM00487 258 454 1.2E-15 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 252 611 5.3E-76 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 Gene3D G3DSA:3.40.50.300 241 451 9.2E-59 T 13-10-2018 CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 Pfam PF00271 Helicase conserved C-terminal domain 476 600 5.0E-13 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 SMART SM00490 508 602 9.1E-18 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 Gene3D G3DSA:3.40.50.300 452 667 1.9E-32 T 13-10-2018 CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 Pfam PF04480 Protein of unknown function (DUF559) 5 68 3.2E-8 T 13-10-2018 IPR007569 Protein of unknown function DUF559 CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 Pfam PF00270 DEAD/DEAH box helicase 266 432 3.1E-13 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 SUPERFAMILY SSF52540 303 613 2.71E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1256 8ceae8d30fc3188fe2bac9eff35624d7 1000 Gene3D G3DSA:3.40.960.10 2 74 1.5E-14 T 13-10-2018 CLOST_1961 b2954712799dfe7524b810880d6eee3a 432 Gene3D G3DSA:3.90.226.10 287 429 1.8E-13 T 13-10-2018 CLOST_1961 b2954712799dfe7524b810880d6eee3a 432 Pfam PF03572 Peptidase family S41 190 409 1.6E-24 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CLOST_1961 b2954712799dfe7524b810880d6eee3a 432 Gene3D G3DSA:3.90.226.10 149 277 7.1E-8 T 13-10-2018 CLOST_1961 b2954712799dfe7524b810880d6eee3a 432 SUPERFAMILY SSF52096 143 424 1.64E-34 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 1.0E-14 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 13-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 Pfam PF01016 Ribosomal L27 protein 10 89 1.2E-36 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 Gene3D G3DSA:2.40.50.100 28 93 1.1E-29 T 13-10-2018 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 28.197 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 SUPERFAMILY SSF110324 10 91 2.59E-33 T 13-10-2018 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 PRINTS PR00063 Ribosomal protein L27 signature 12 36 4.4E-40 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 PRINTS PR00063 Ribosomal protein L27 signature 37 61 4.4E-40 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 PRINTS PR00063 Ribosomal protein L27 signature 62 86 4.4E-40 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1372 e5d3a160f1ba543485f1fbe6ca73ad9c 95 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 1.9E-40 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 60 270 9.7E-56 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 Pfam PF07549 SecD/SecF GG Motif 31 47 1.9E-6 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 29 273 4.3E-77 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 Gene3D G3DSA:1.20.1640.10 92 285 2.3E-11 T 13-10-2018 CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 1 284 26.957 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 SUPERFAMILY SSF82866 108 283 1.96E-38 T 13-10-2018 CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 PRINTS PR01755 Bacterial translocase SecF protein signature 28 43 8.1E-31 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 PRINTS PR01755 Bacterial translocase SecF protein signature 141 155 8.1E-31 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 PRINTS PR01755 Bacterial translocase SecF protein signature 189 207 8.1E-31 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 PRINTS PR01755 Bacterial translocase SecF protein signature 221 236 8.1E-31 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CLOST_1309 71707a563e4f231da1bbd8618257a2c6 287 Pfam PF02355 Protein export membrane protein 107 282 5.0E-67 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 160 172 1.5E-23 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.5E-23 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.5E-23 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 1.5E-23 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 248 2.8E-96 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 Gene3D G3DSA:3.90.230.10 1 248 1.9E-97 T 13-10-2018 CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 Pfam PF00557 Metallopeptidase family M24 11 239 1.3E-47 T 13-10-2018 IPR000994 Peptidase M24 CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 166 184 - T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 SUPERFAMILY SSF55920 1 247 2.62E-83 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like CLOST_2176 83cf74a50ed27c93294fc7b9e0b74585 249 Hamap MF_01974 Methionine aminopeptidase [map]. 2 249 40.558 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CLOST_0101 13576da725f7d76bcfaecf91da8a8ef7 292 ProSitePatterns PS01235 PdxS/SNZ family signature. 203 221 - T 13-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0101 13576da725f7d76bcfaecf91da8a8ef7 292 PIRSF PIRSF029271 2 292 9.8E-151 T 13-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0101 13576da725f7d76bcfaecf91da8a8ef7 292 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 2 292 51.199 T 13-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0101 13576da725f7d76bcfaecf91da8a8ef7 292 Pfam PF01680 SOR/SNZ family 6 210 5.4E-109 T 13-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0101 13576da725f7d76bcfaecf91da8a8ef7 292 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 7 292 6.2E-152 T 13-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0101 13576da725f7d76bcfaecf91da8a8ef7 292 Gene3D G3DSA:3.20.20.70 1 290 3.9E-149 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0101 13576da725f7d76bcfaecf91da8a8ef7 292 SUPERFAMILY SSF51366 16 266 1.18E-66 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CLOST_2336 8bc1c35019aeacef8529ae86c19aca2a 358 SUPERFAMILY SSF55347 129 262 1.26E-35 T 13-10-2018 CLOST_2336 8bc1c35019aeacef8529ae86c19aca2a 358 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 232 1.7E-11 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 CLOST_2336 8bc1c35019aeacef8529ae86c19aca2a 358 Gene3D G3DSA:3.40.50.720 2 316 3.8E-98 T 13-10-2018 CLOST_2336 8bc1c35019aeacef8529ae86c19aca2a 358 Gene3D G3DSA:3.30.360.10 130 338 3.8E-98 T 13-10-2018 CLOST_2336 8bc1c35019aeacef8529ae86c19aca2a 358 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 119 4.7E-22 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CLOST_2336 8bc1c35019aeacef8529ae86c19aca2a 358 SUPERFAMILY SSF51735 1 197 4.11E-38 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 Gene3D G3DSA:2.40.30.10 208 337 3.2E-54 T 13-10-2018 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 Gene3D G3DSA:3.40.50.300 1 205 3.1E-70 T 13-10-2018 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 132 141 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 SUPERFAMILY SSF50447 207 304 7.86E-31 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 1.7E-15 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 SUPERFAMILY SSF52540 6 221 1.09E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 SUPERFAMILY SSF50465 306 397 1.68E-35 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 60.549 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 9.6E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.2E-59 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 397 1.5E-226 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 Gene3D G3DSA:2.40.30.10 341 396 8.2E-28 T 13-10-2018 CLOST_2206 d15a1ec006ad82a3cc24a34dbfe588e9 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 4.4E-33 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 Gene3D G3DSA:2.40.30.10 208 337 3.2E-54 T 13-10-2018 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 Gene3D G3DSA:3.40.50.300 1 205 3.1E-70 T 13-10-2018 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 132 141 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 79 89 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 PRINTS PR00315 GTP-binding elongation factor signature 95 106 3.1E-25 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 SUPERFAMILY SSF50447 207 304 7.86E-31 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 1.7E-15 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 SUPERFAMILY SSF52540 6 221 1.09E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 SUPERFAMILY SSF50465 306 397 1.68E-35 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 60.549 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 9.6E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.2E-59 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 397 1.5E-226 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 Gene3D G3DSA:2.40.30.10 341 396 8.2E-28 T 13-10-2018 CLOST_2219 d15a1ec006ad82a3cc24a34dbfe588e9 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 4.4E-33 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 PIRSF PIRSF001549 4 430 1.3E-119 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 Pfam PF03129 Anticodon binding domain 349 430 3.7E-12 T 13-10-2018 IPR004154 Anticodon-binding CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 Gene3D G3DSA:3.30.930.10 2 341 2.4E-99 T 13-10-2018 CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 6 430 25.346 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 Pfam PF13393 Histidyl-tRNA synthetase 13 328 1.4E-39 T 13-10-2018 CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 SUPERFAMILY SSF55681 9 339 9.76E-71 T 13-10-2018 CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 11 426 6.2E-111 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 Gene3D G3DSA:3.40.50.800 346 430 7.5E-19 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily CLOST_1041 a21c7b24b4be32243de1569fb44f33d1 430 SUPERFAMILY SSF52954 348 430 1.8E-16 T 13-10-2018 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 Hamap MF_00318 Enolase [eno]. 1 412 46.134 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 Gene3D G3DSA:3.30.390.10 1 126 2.9E-59 T 13-10-2018 IPR029017 Enolase-like, N-terminal CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 Pfam PF03952 Enolase, N-terminal domain 3 133 6.9E-63 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 Gene3D G3DSA:3.20.20.120 127 430 2.0E-140 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 PRINTS PR00148 Enolase signature 106 122 2.8E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 PRINTS PR00148 Enolase signature 364 381 2.8E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 PRINTS PR00148 Enolase signature 36 50 2.8E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 PRINTS PR00148 Enolase signature 160 173 2.8E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 PRINTS PR00148 Enolase signature 312 323 2.8E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 PRINTS PR00148 Enolase signature 335 349 2.8E-48 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 SMART SM01192 138 426 8.5E-226 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 3 426 2.8E-219 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 SUPERFAMILY SSF54826 1 137 1.28E-61 T 13-10-2018 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 425 1.6E-139 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 SMART SM01193 3 133 2.3E-101 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 SUPERFAMILY SSF51604 137 427 2.4E-131 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 PIRSF PIRSF001400 1 426 2.7E-196 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0646 09beaec8dfe3dc57f777c396986fdafc 430 ProSitePatterns PS00164 Enolase signature. 335 348 - T 13-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 192 737 8.1E-168 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00941 Cadmium-transporting ATPase signature 326 340 5.3E-8 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00941 Cadmium-transporting ATPase signature 8 17 5.3E-8 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00941 Cadmium-transporting ATPase signature 226 246 5.3E-8 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00941 Cadmium-transporting ATPase signature 155 172 5.3E-8 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00941 Cadmium-transporting ATPase signature 307 323 5.3E-8 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 Gene3D G3DSA:2.70.150.20 234 346 1.3E-28 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 SUPERFAMILY SSF56784 442 735 2.84E-58 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 215 715 5.8E-73 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 SUPERFAMILY SSF81665 192 435 1.22E-14 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 Gene3D G3DSA:3.40.1110.10 453 563 5.2E-79 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 444 450 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 Gene3D G3DSA:3.40.50.1000 423 687 5.2E-79 T 13-10-2018 IPR023214 HAD superfamily CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 442 456 1.2E-22 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 291 305 1.2E-22 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 654 1.2E-22 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 659 671 1.2E-22 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 579 589 1.2E-22 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 567 1.2E-22 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 192 739 8.1E-158 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 Pfam PF00702 haloacid dehalogenase-like hydrolase 441 649 3.0E-31 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 SUPERFAMILY SSF81653 244 341 1.1E-21 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 Pfam PF00403 Heavy-metal-associated domain 7 63 1.5E-7 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 SUPERFAMILY SSF55008 3 65 1.19E-10 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 Pfam PF00122 E1-E2 ATPase 243 422 2.7E-49 T 13-10-2018 CLOST_0567 054fb054b6d68f116fe9b2fa72e06d8d 741 Gene3D G3DSA:3.30.70.100 4 80 1.5E-9 T 13-10-2018 CLOST_2214 a650117a9e146c14e800eb0900ea5e9b 232 PIRSF PIRSF002155 1 228 2.2E-81 T 13-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2214 a650117a9e146c14e800eb0900ea5e9b 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.0E-102 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CLOST_2214 a650117a9e146c14e800eb0900ea5e9b 232 Pfam PF00687 Ribosomal protein L1p/L10e family 32 221 5.6E-59 T 13-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CLOST_2214 a650117a9e146c14e800eb0900ea5e9b 232 Gene3D G3DSA:3.40.50.790 68 160 3.0E-85 T 13-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CLOST_2214 a650117a9e146c14e800eb0900ea5e9b 232 Gene3D G3DSA:3.30.190.20 23 226 3.0E-85 T 13-10-2018 CLOST_2214 a650117a9e146c14e800eb0900ea5e9b 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 140 - T 13-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2214 a650117a9e146c14e800eb0900ea5e9b 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 230 43.881 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CLOST_2214 a650117a9e146c14e800eb0900ea5e9b 232 SUPERFAMILY SSF56808 6 226 1.7E-85 T 13-10-2018 IPR023674 Ribosomal protein L1-like CLOST_0139 d2e7b83993243b3068b26729750052b8 348 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 342 43.023 T 13-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CLOST_0139 d2e7b83993243b3068b26729750052b8 348 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 147 163 - T 13-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CLOST_0139 d2e7b83993243b3068b26729750052b8 348 SUPERFAMILY SSF51735 2 176 3.12E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0139 d2e7b83993243b3068b26729750052b8 348 Gene3D G3DSA:3.30.360.10 150 316 4.1E-133 T 13-10-2018 CLOST_0139 d2e7b83993243b3068b26729750052b8 348 Gene3D G3DSA:3.40.50.720 3 334 4.1E-133 T 13-10-2018 CLOST_0139 d2e7b83993243b3068b26729750052b8 348 SUPERFAMILY SSF55347 152 315 1.64E-54 T 13-10-2018 CLOST_0139 d2e7b83993243b3068b26729750052b8 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 161 319 8.9E-23 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CLOST_0139 d2e7b83993243b3068b26729750052b8 348 SMART SM00859 3 144 3.2E-46 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CLOST_0139 d2e7b83993243b3068b26729750052b8 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 144 1.8E-29 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CLOST_0139 d2e7b83993243b3068b26729750052b8 348 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 348 1.6E-133 T 13-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CLOST_0629 f6157ae444ecee3a2fc72a5703d5f505 380 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 363 1.7E-85 T 13-10-2018 IPR017439 Amidohydrolase GO:0016787 CLOST_0629 f6157ae444ecee3a2fc72a5703d5f505 380 SUPERFAMILY SSF53187 4 374 2.9E-57 T 13-10-2018 CLOST_0629 f6157ae444ecee3a2fc72a5703d5f505 380 Pfam PF07687 Peptidase dimerisation domain 176 269 6.8E-12 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain CLOST_0629 f6157ae444ecee3a2fc72a5703d5f505 380 SUPERFAMILY SSF55031 176 288 3.93E-29 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain CLOST_0629 f6157ae444ecee3a2fc72a5703d5f505 380 Gene3D G3DSA:3.30.70.360 173 287 3.6E-111 T 13-10-2018 CLOST_0629 f6157ae444ecee3a2fc72a5703d5f505 380 Gene3D G3DSA:3.40.630.10 20 363 3.6E-111 T 13-10-2018 CLOST_0629 f6157ae444ecee3a2fc72a5703d5f505 380 Pfam PF01546 Peptidase family M20/M25/M40 74 375 4.9E-23 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 CLOST_0629 f6157ae444ecee3a2fc72a5703d5f505 380 PIRSF PIRSF005962 3 379 3.1E-108 T 13-10-2018 IPR017439 Amidohydrolase GO:0016787 CLOST_0439 47d529b3d2719c6dad12ae3a82f8a50a 268 Gene3D G3DSA:3.30.565.40 52 167 1.3E-21 T 13-10-2018 CLOST_0439 47d529b3d2719c6dad12ae3a82f8a50a 268 Pfam PF11738 Protein of unknown function (DUF3298) 171 247 1.8E-16 T 13-10-2018 IPR021729 Domain of unknown function DUF3298 CLOST_0439 47d529b3d2719c6dad12ae3a82f8a50a 268 Gene3D G3DSA:3.90.640.20 169 267 4.9E-20 T 13-10-2018 IPR037126 PdaC/RsiV-like superfamily CLOST_0439 47d529b3d2719c6dad12ae3a82f8a50a 268 Pfam PF13739 Domain of unknown function (DUF4163) 64 153 1.2E-16 T 13-10-2018 IPR025303 Deacetylase PdaC CLOST_0432 ff59d2f4593c2092337d53f8fb7519a1 448 SUPERFAMILY SSF53187 42 304 2.21E-50 T 13-10-2018 CLOST_0432 ff59d2f4593c2092337d53f8fb7519a1 448 Gene3D G3DSA:3.40.630.10 29 324 8.3E-63 T 13-10-2018 CLOST_0432 ff59d2f4593c2092337d53f8fb7519a1 448 Pfam PF04389 Peptidase family M28 96 312 6.0E-36 T 13-10-2018 IPR007484 Peptidase M28 CLOST_0432 ff59d2f4593c2092337d53f8fb7519a1 448 SUPERFAMILY SSF55383 332 384 5.23E-5 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0432 ff59d2f4593c2092337d53f8fb7519a1 448 SUPERFAMILY SSF55383 370 441 5.49E-5 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0432 ff59d2f4593c2092337d53f8fb7519a1 448 Pfam PF07833 Copper amine oxidase N-terminal domain 331 389 1.1E-6 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0432 ff59d2f4593c2092337d53f8fb7519a1 448 Pfam PF07833 Copper amine oxidase N-terminal domain 373 446 1.8E-6 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_2335 b91bfe1d5eb9d8b70f9b03c0a1876d9f 187 SUPERFAMILY SSF51161 3 160 5.19E-43 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_2335 b91bfe1d5eb9d8b70f9b03c0a1876d9f 187 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 33 65 6.0E-8 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_2335 b91bfe1d5eb9d8b70f9b03c0a1876d9f 187 Gene3D G3DSA:2.160.10.10 2 153 2.1E-42 T 13-10-2018 CLOST_2297 a66c69aca9b116b19363d1a14576aeca 209 Gene3D G3DSA:1.10.10.10 1 75 2.3E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2297 a66c69aca9b116b19363d1a14576aeca 209 SUPERFAMILY SSF51735 81 205 2.36E-27 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_2297 a66c69aca9b116b19363d1a14576aeca 209 Pfam PF02629 CoA binding domain 80 177 3.1E-25 T 13-10-2018 IPR003781 CoA-binding GO:0048037 CLOST_2297 a66c69aca9b116b19363d1a14576aeca 209 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 208 35.684 T 13-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CLOST_2297 a66c69aca9b116b19363d1a14576aeca 209 Pfam PF06971 Putative DNA-binding protein N-terminus 4 52 1.8E-19 T 13-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CLOST_2297 a66c69aca9b116b19363d1a14576aeca 209 SMART SM00881 78 179 4.3E-21 T 13-10-2018 IPR003781 CoA-binding GO:0048037 CLOST_2297 a66c69aca9b116b19363d1a14576aeca 209 Gene3D G3DSA:3.40.50.720 76 207 7.5E-49 T 13-10-2018 CLOST_2297 a66c69aca9b116b19363d1a14576aeca 209 SUPERFAMILY SSF46785 8 78 3.26E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0361 e67622737b2988bc6d1dd2c1a17abe30 395 Gene3D G3DSA:3.40.50.2000 115 232 2.3E-12 T 13-10-2018 CLOST_0361 e67622737b2988bc6d1dd2c1a17abe30 395 SUPERFAMILY SSF53756 115 340 1.3E-25 T 13-10-2018 CLOST_0361 e67622737b2988bc6d1dd2c1a17abe30 395 Gene3D G3DSA:3.40.50.2000 233 338 2.3E-12 T 13-10-2018 CLOST_0361 e67622737b2988bc6d1dd2c1a17abe30 395 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 186 346 2.3E-12 T 13-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CLOST_1629 8c6636478b30f6d60fb9911c36eb317a 262 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 98 260 1.0E-8 T 13-10-2018 CLOST_1629 8c6636478b30f6d60fb9911c36eb317a 262 Pfam PF12787 EcsC protein family 7 258 2.1E-58 T 13-10-2018 IPR024787 EcsC protein CLOST_1756 41787c928cd5984d429966bc9547bca0 580 Pfam PF01807 CHC2 zinc finger 3 96 4.5E-36 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 TIGRFAM TIGR01391 dnaG: DNA primase 1 400 9.8E-132 T 13-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 Gene3D G3DSA:3.90.580.10 1 99 2.4E-38 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 Pfam PF13155 Toprim-like 255 340 1.0E-18 T 13-10-2018 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 Gene3D G3DSA:3.90.980.10 110 235 1.1E-37 T 13-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily CLOST_1756 41787c928cd5984d429966bc9547bca0 580 SMART SM00493 252 323 1.7E-16 T 13-10-2018 IPR006171 TOPRIM domain CLOST_1756 41787c928cd5984d429966bc9547bca0 580 Pfam PF08275 DNA primase catalytic core, N-terminal domain 126 246 6.7E-36 T 13-10-2018 IPR013264 DNA primase, catalytic core, N-terminal CLOST_1756 41787c928cd5984d429966bc9547bca0 580 SUPERFAMILY SSF56731 114 412 2.62E-88 T 13-10-2018 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 SUPERFAMILY SSF57783 1 96 1.11E-34 T 13-10-2018 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 SMART SM00400 33 87 6.9E-34 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 Hamap MF_00974 DNA primase [dnaG]. 1 568 26.16 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 PIRSF PIRSF002811 1 578 5.4E-147 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CLOST_1756 41787c928cd5984d429966bc9547bca0 580 Gene3D G3DSA:3.40.1360.10 236 358 2.4E-35 T 13-10-2018 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 Gene3D G3DSA:3.90.1170.10 1 146 3.5E-57 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 SUPERFAMILY SSF54686 1 138 1.57E-59 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 5.2E-53 T 13-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 40.16 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 PRINTS PR00060 Ribosomal protein L16 signature 58 87 6.0E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 PRINTS PR00060 Ribosomal protein L16 signature 42 53 6.0E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 PRINTS PR00060 Ribosomal protein L16 signature 88 117 6.0E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 PRINTS PR00060 Ribosomal protein L16 signature 24 36 6.0E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2191 7bd1f40c5ace51b24119c545e8478742 147 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 3.2E-60 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1619 75d7ec3316c37b76d1b765c8c532ab4a 492 SUPERFAMILY SSF52540 294 485 1.4E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1619 75d7ec3316c37b76d1b765c8c532ab4a 492 Gene3D G3DSA:3.40.50.300 236 491 1.5E-98 T 13-10-2018 CLOST_1619 75d7ec3316c37b76d1b765c8c532ab4a 492 Gene3D G3DSA:3.40.50.300 1 234 3.6E-73 T 13-10-2018 CLOST_1619 75d7ec3316c37b76d1b765c8c532ab4a 492 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 19 230 2.5E-56 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related CLOST_1619 75d7ec3316c37b76d1b765c8c532ab4a 492 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 265 491 1.8E-81 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related CLOST_1619 75d7ec3316c37b76d1b765c8c532ab4a 492 SUPERFAMILY SSF52540 40 220 7.98E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0311 9c13d6d471ba3fc55bd40ad761732180 432 SUPERFAMILY SSF46785 370 430 4.07E-6 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0311 9c13d6d471ba3fc55bd40ad761732180 432 Gene3D G3DSA:3.30.565.60 196 360 3.3E-41 T 13-10-2018 IPR038475 RecG, C-terminal domain superfamily CLOST_0311 9c13d6d471ba3fc55bd40ad761732180 432 Pfam PF04326 Putative DNA-binding domain 2 120 4.5E-22 T 13-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 CLOST_0311 9c13d6d471ba3fc55bd40ad761732180 432 Gene3D G3DSA:3.30.950.30 1 125 2.8E-28 T 13-10-2018 IPR038461 Schlafen, AAA domain superfamily CLOST_0311 9c13d6d471ba3fc55bd40ad761732180 432 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 276 356 2.6E-15 T 13-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain CLOST_0001 673b0fe806787b52582c43266c34a234 440 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 235 262 1.2E-52 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CLOST_0001 673b0fe806787b52582c43266c34a234 440 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 201 215 1.2E-52 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CLOST_0001 673b0fe806787b52582c43266c34a234 440 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 137 157 1.2E-52 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CLOST_0001 673b0fe806787b52582c43266c34a234 440 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 398 417 1.2E-52 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CLOST_0001 673b0fe806787b52582c43266c34a234 440 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 169 183 1.2E-52 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CLOST_0001 673b0fe806787b52582c43266c34a234 440 Gene3D G3DSA:1.10.1750.10 339 439 2.5E-36 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CLOST_0001 673b0fe806787b52582c43266c34a234 440 SMART SM00382 136 264 5.6E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0001 673b0fe806787b52582c43266c34a234 440 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 351 417 1.4E-32 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CLOST_0001 673b0fe806787b52582c43266c34a234 440 SUPERFAMILY SSF48295 335 440 4.19E-36 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CLOST_0001 673b0fe806787b52582c43266c34a234 440 SMART SM00760 348 417 4.8E-39 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CLOST_0001 673b0fe806787b52582c43266c34a234 440 Pfam PF11638 DnaA N-terminal domain 5 65 1.1E-9 T 13-10-2018 IPR024633 DnaA N-terminal domain CLOST_0001 673b0fe806787b52582c43266c34a234 440 ProSitePatterns PS01008 DnaA protein signature. 398 417 - T 13-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CLOST_0001 673b0fe806787b52582c43266c34a234 440 Gene3D G3DSA:1.10.8.60 270 338 1.2E-28 T 13-10-2018 CLOST_0001 673b0fe806787b52582c43266c34a234 440 Gene3D G3DSA:3.30.300.180 1 80 1.9E-12 T 13-10-2018 IPR038454 DnaA, N-terminal domain superfamily CLOST_0001 673b0fe806787b52582c43266c34a234 440 SUPERFAMILY SSF52540 103 315 6.1E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0001 673b0fe806787b52582c43266c34a234 440 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 7 437 7.5E-173 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CLOST_0001 673b0fe806787b52582c43266c34a234 440 Gene3D G3DSA:3.40.50.300 90 268 2.2E-55 T 13-10-2018 CLOST_0001 673b0fe806787b52582c43266c34a234 440 Pfam PF00308 Bacterial dnaA protein 104 321 2.1E-103 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA CLOST_0001 673b0fe806787b52582c43266c34a234 440 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 4 439 33.121 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 SUPERFAMILY SSF53067 254 496 1.78E-88 T 13-10-2018 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 Gene3D G3DSA:3.30.420.40 1 252 1.6E-110 T 13-10-2018 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 495 1.4E-232 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 1.6E-62 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 61.399 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 Gene3D G3DSA:3.30.420.40 253 499 4.6E-93 T 13-10-2018 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 SUPERFAMILY SSF53067 4 254 2.59E-97 T 13-10-2018 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 1.7E-86 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 PIRSF PIRSF000538 2 499 1.0E-188 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CLOST_1952 36eac5c28f2bf253bdc3f0f996e514be 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 2.3E-28 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 SUPERFAMILY SSF143034 2 64 1.02E-24 T 13-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.7E-22 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.7E-22 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.7E-22 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 Pfam PF01632 Ribosomal protein L35 2 62 1.8E-26 T 13-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 Gene3D G3DSA:2.40.50.530 1 64 1.0E-25 T 13-10-2018 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.673 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CLOST_1130 4445998d86e1b0dae04e06eced534fc0 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 13-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1387 275eae13ec0b8981923c590cb28f1317 368 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 10 363 5.2E-104 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1387 275eae13ec0b8981923c590cb28f1317 368 Pfam PF01098 Cell cycle protein 13 364 3.2E-94 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1387 275eae13ec0b8981923c590cb28f1317 368 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 321 345 - T 13-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 PIRSF PIRSF011572 1 258 1.2E-109 T 13-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 126.296 T 13-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 Gene3D G3DSA:3.30.450.40 2 160 1.5E-53 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 5 254 3.5E-108 T 13-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 Gene3D G3DSA:1.10.10.10 161 259 1.8E-46 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 Pfam PF06018 CodY GAF-like domain 5 179 2.8E-59 T 13-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 SUPERFAMILY SSF46785 168 257 2.51E-42 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 Pfam PF08222 CodY helix-turn-helix domain 199 257 2.2E-35 T 13-10-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CLOST_1497 c5e02045ee87f38d67cde1cadd29383d 259 SUPERFAMILY SSF55781 112 162 1.32E-5 T 13-10-2018 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 Gene3D G3DSA:1.10.8.60 332 409 2.3E-28 T 13-10-2018 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 Gene3D G3DSA:3.40.50.300 148 330 1.9E-69 T 13-10-2018 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 Gene3D G3DSA:1.20.58.760 412 621 4.1E-74 T 13-10-2018 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 618 37.16 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 Pfam PF06480 FtsH Extracellular 10 100 4.2E-11 T 13-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 329 1.6E-43 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 ProSitePatterns PS00674 AAA-protein family signature. 301 319 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 110 599 2.1E-233 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 Pfam PF01434 Peptidase family M41 392 599 1.3E-77 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 SUPERFAMILY SSF140990 412 603 1.31E-71 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 SUPERFAMILY SSF52540 155 401 8.3E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0937 81f557cead4e03af6ddf3641a4ded4cf 656 SMART SM00382 194 333 7.9E-24 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1044 b4652229003092857eba5039a6f432d8 208 Gene3D G3DSA:3.60.15.10 1 206 2.0E-56 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1044 b4652229003092857eba5039a6f432d8 208 SMART SM00849 12 190 2.2E-36 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1044 b4652229003092857eba5039a6f432d8 208 SUPERFAMILY SSF56281 8 203 3.41E-48 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1044 b4652229003092857eba5039a6f432d8 208 Pfam PF00753 Metallo-beta-lactamase superfamily 13 173 9.7E-28 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1470 988eb019d155e8532498afac5063549c 289 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 79 1.1E-12 T 13-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CLOST_1470 988eb019d155e8532498afac5063549c 289 SUPERFAMILY SSF46689 8 85 5.02E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_1470 988eb019d155e8532498afac5063549c 289 Pfam PF01380 SIS domain 134 260 3.4E-29 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CLOST_1470 988eb019d155e8532498afac5063549c 289 SUPERFAMILY SSF53697 103 284 7.89E-32 T 13-10-2018 CLOST_1470 988eb019d155e8532498afac5063549c 289 Gene3D G3DSA:1.10.10.10 5 83 3.0E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1470 988eb019d155e8532498afac5063549c 289 Gene3D G3DSA:3.40.50.10490 101 285 1.7E-41 T 13-10-2018 CLOST_0551 8b1178f6b14a6492e8d4b6ed2ed6737a 317 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 5 309 5.7E-73 T 13-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 CLOST_0551 8b1178f6b14a6492e8d4b6ed2ed6737a 317 Pfam PF01699 Sodium/calcium exchanger protein 2 150 2.9E-30 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CLOST_0551 8b1178f6b14a6492e8d4b6ed2ed6737a 317 Pfam PF01699 Sodium/calcium exchanger protein 174 314 1.0E-29 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CLOST_0551 8b1178f6b14a6492e8d4b6ed2ed6737a 317 Gene3D G3DSA:1.20.1420.30 33 307 1.6E-91 T 13-10-2018 CLOST_0551 8b1178f6b14a6492e8d4b6ed2ed6737a 317 Gene3D G3DSA:1.20.58.1130 7 206 1.6E-91 T 13-10-2018 CLOST_1369 634ddeeaed7bf011ffee24af5f6a9359 200 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 8 197 8.2E-55 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CLOST_1369 634ddeeaed7bf011ffee24af5f6a9359 200 Pfam PF01467 Cytidylyltransferase-like 8 172 1.7E-31 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CLOST_1369 634ddeeaed7bf011ffee24af5f6a9359 200 Gene3D G3DSA:3.40.50.620 2 200 3.3E-63 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1369 634ddeeaed7bf011ffee24af5f6a9359 200 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 4 198 30.72 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CLOST_1369 634ddeeaed7bf011ffee24af5f6a9359 200 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 69 2.0E-11 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CLOST_1369 634ddeeaed7bf011ffee24af5f6a9359 200 SUPERFAMILY SSF52374 2 198 2.13E-51 T 13-10-2018 CLOST_1982 d38119696325972bfd58ca41796f7080 864 Gene3D G3DSA:3.40.50.300 553 769 1.2E-85 T 13-10-2018 CLOST_1982 d38119696325972bfd58ca41796f7080 864 SUPERFAMILY SSF52540 159 548 2.7E-99 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1982 d38119696325972bfd58ca41796f7080 864 Gene3D G3DSA:3.40.50.300 151 344 1.0E-75 T 13-10-2018 CLOST_1982 d38119696325972bfd58ca41796f7080 864 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 765 5.2E-54 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_1982 d38119696325972bfd58ca41796f7080 864 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CLOST_1982 d38119696325972bfd58ca41796f7080 864 Gene3D G3DSA:1.10.8.60 771 862 4.0E-25 T 13-10-2018 CLOST_1982 d38119696325972bfd58ca41796f7080 864 Gene3D G3DSA:1.10.1780.10 1 150 1.7E-32 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 CLOST_1982 d38119696325972bfd58ca41796f7080 864 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 CLOST_1982 d38119696325972bfd58ca41796f7080 864 Gene3D G3DSA:3.40.50.300 345 547 8.1E-68 T 13-10-2018 CLOST_1982 d38119696325972bfd58ca41796f7080 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 6.2E-10 T 13-10-2018 IPR004176 Clp, N-terminal CLOST_1982 d38119696325972bfd58ca41796f7080 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 63 3.2E-8 T 13-10-2018 IPR004176 Clp, N-terminal CLOST_1982 d38119696325972bfd58ca41796f7080 864 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 771 850 1.9E-25 T 13-10-2018 IPR019489 Clp ATPase, C-terminal CLOST_1982 d38119696325972bfd58ca41796f7080 864 SMART SM00382 600 772 6.9E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1982 d38119696325972bfd58ca41796f7080 864 SMART SM00382 200 344 4.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1982 d38119696325972bfd58ca41796f7080 864 SMART SM01086 771 860 8.3E-31 T 13-10-2018 IPR019489 Clp ATPase, C-terminal CLOST_1982 d38119696325972bfd58ca41796f7080 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 2.6E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_1982 d38119696325972bfd58ca41796f7080 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 2.6E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_1982 d38119696325972bfd58ca41796f7080 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 2.6E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_1982 d38119696325972bfd58ca41796f7080 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 2.6E-41 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_1982 d38119696325972bfd58ca41796f7080 864 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 321 4.9E-13 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_1982 d38119696325972bfd58ca41796f7080 864 SUPERFAMILY SSF81923 4 158 1.86E-36 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 CLOST_1982 d38119696325972bfd58ca41796f7080 864 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 859 0.0 T 13-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 CLOST_1982 d38119696325972bfd58ca41796f7080 864 SUPERFAMILY SSF52540 549 857 2.02E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2502 5806e588e6b3b6e68b78f09afa3564d7 305 SUPERFAMILY SSF48150 115 303 1.36E-41 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CLOST_2502 5806e588e6b3b6e68b78f09afa3564d7 305 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 48 131 2.9E-6 T 13-10-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 CLOST_2502 5806e588e6b3b6e68b78f09afa3564d7 305 Gene3D G3DSA:1.10.1670.40 102 298 2.0E-42 T 13-10-2018 CLOST_2502 5806e588e6b3b6e68b78f09afa3564d7 305 SMART SM00478 136 301 1.8E-22 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CLOST_2502 5806e588e6b3b6e68b78f09afa3564d7 305 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 132 285 1.7E-15 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CLOST_2502 5806e588e6b3b6e68b78f09afa3564d7 305 Gene3D G3DSA:1.10.340.30 126 248 2.0E-42 T 13-10-2018 CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 13-10-2018 IPR018253 DnaJ domain, conserved site CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 Pfam PF01556 DnaJ C terminal domain 128 344 5.9E-46 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 380 43.448 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 Gene3D G3DSA:2.10.230.10 154 218 2.8E-36 T 13-10-2018 CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 SUPERFAMILY SSF46565 2 110 4.97E-40 T 13-10-2018 IPR036869 Chaperone J-domain superfamily CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 361 7.3E-149 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 SUPERFAMILY SSF49493 120 277 6.02E-19 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 Gene3D G3DSA:2.60.260.20 124 260 2.8E-36 T 13-10-2018 CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 SMART SM00271 4 62 3.7E-34 T 13-10-2018 IPR001623 DnaJ domain CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 PRINTS PR00625 DnaJ domain signature 25 40 6.3E-34 T 13-10-2018 IPR001623 DnaJ domain CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 PRINTS PR00625 DnaJ domain signature 7 25 6.3E-34 T 13-10-2018 IPR001623 DnaJ domain CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 PRINTS PR00625 DnaJ domain signature 62 81 6.3E-34 T 13-10-2018 IPR001623 DnaJ domain CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 PRINTS PR00625 DnaJ domain signature 42 62 6.3E-34 T 13-10-2018 IPR001623 DnaJ domain CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 Pfam PF00226 DnaJ domain 5 67 1.6E-30 T 13-10-2018 IPR001623 DnaJ domain CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 Gene3D G3DSA:2.60.260.20 265 375 4.2E-32 T 13-10-2018 CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 SUPERFAMILY SSF49493 270 355 2.09E-25 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 Gene3D G3DSA:1.10.287.110 1 117 6.2E-41 T 13-10-2018 IPR036869 Chaperone J-domain superfamily CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 SUPERFAMILY SSF57938 141 222 1.83E-19 T 13-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily CLOST_1792 7605f79e122fc07bcf52dc752aa98ea3 382 Pfam PF00684 DnaJ central domain 154 218 4.4E-15 T 13-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CLOST_1313 b5afdcd2f3253826e46fbe25ac1e422d 341 Pfam PF02547 Queuosine biosynthesis protein 4 340 1.3E-137 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CLOST_1313 b5afdcd2f3253826e46fbe25ac1e422d 341 SUPERFAMILY SSF111337 1 341 3.79E-136 T 13-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CLOST_1313 b5afdcd2f3253826e46fbe25ac1e422d 341 Gene3D G3DSA:3.40.1780.10 14 340 5.0E-131 T 13-10-2018 CLOST_1313 b5afdcd2f3253826e46fbe25ac1e422d 341 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 341 45.39 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CLOST_1313 b5afdcd2f3253826e46fbe25ac1e422d 341 Gene3D G3DSA:2.40.10.240 64 162 5.0E-131 T 13-10-2018 CLOST_1313 b5afdcd2f3253826e46fbe25ac1e422d 341 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2 340 3.4E-140 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CLOST_1945 ffdcdefd05a9a99fa3ae0775107e4e41 421 SUPERFAMILY SSF51735 128 267 3.8E-10 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1945 ffdcdefd05a9a99fa3ae0775107e4e41 421 Gene3D G3DSA:3.40.50.720 118 269 7.6E-21 T 13-10-2018 CLOST_1945 ffdcdefd05a9a99fa3ae0775107e4e41 421 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 128 267 6.5E-6 T 13-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CLOST_1448 5cf89e62c7e27657fd5b093675d7f0d8 256 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 246 6.1E-75 T 13-10-2018 IPR008275 CoA enzyme activase CLOST_1448 5cf89e62c7e27657fd5b093675d7f0d8 256 Gene3D G3DSA:3.30.420.40 89 230 3.5E-68 T 13-10-2018 CLOST_1448 5cf89e62c7e27657fd5b093675d7f0d8 256 SUPERFAMILY SSF53067 3 245 5.1E-34 T 13-10-2018 CLOST_1448 5cf89e62c7e27657fd5b093675d7f0d8 256 Gene3D G3DSA:3.30.420.40 4 246 3.5E-68 T 13-10-2018 CLOST_1448 5cf89e62c7e27657fd5b093675d7f0d8 256 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 246 1.7E-45 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CLOST_1116 25e7837ea72bc833c106d8499884f62f 388 SUPERFAMILY SSF53659 27 292 1.32E-25 T 13-10-2018 CLOST_1116 25e7837ea72bc833c106d8499884f62f 388 Gene3D G3DSA:3.40.718.10 110 238 1.6E-14 T 13-10-2018 CLOST_1116 25e7837ea72bc833c106d8499884f62f 388 PIRSF PIRSF036593 1 382 8.2E-223 T 13-10-2018 IPR012116 Glycine/sarcosine/betaine reductase complex, protein C, alpha subunit CLOST_1116 25e7837ea72bc833c106d8499884f62f 388 Pfam PF02504 Fatty acid synthesis protein 28 361 1.4E-57 T 13-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 146 6.1E-15 T 13-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 345 352 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 Gene3D G3DSA:3.40.220.10 1 173 5.1E-26 T 13-10-2018 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 498 34.236 T 13-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 SUPERFAMILY SSF52949 1 176 4.65E-17 T 13-10-2018 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 PRINTS PR00481 Cytosol aminopeptidase signature 370 385 2.2E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 PRINTS PR00481 Cytosol aminopeptidase signature 260 277 2.2E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 PRINTS PR00481 Cytosol aminopeptidase signature 319 340 2.2E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 PRINTS PR00481 Cytosol aminopeptidase signature 282 303 2.2E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 PRINTS PR00481 Cytosol aminopeptidase signature 341 361 2.2E-51 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 489 7.9E-120 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 Gene3D G3DSA:3.40.630.10 174 496 2.3E-127 T 13-10-2018 CLOST_0169 1d1b8e755b42afa189a1c5130cbaedb0 498 SUPERFAMILY SSF53187 180 494 5.02E-113 T 13-10-2018 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 Pfam PF12838 4Fe-4S dicluster domain 176 223 2.4E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 148 164 - T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 TIGRFAM TIGR02912 sulfite_red_C: sulfite reductase, subunit C 3 317 3.0E-150 T 13-10-2018 IPR014261 Sulphite reductase, subunit C CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 Gene3D G3DSA:3.30.70.20 169 231 4.2E-12 T 13-10-2018 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 PRINTS PR00397 Sirohaem Fe-binding site signature 148 166 8.1E-7 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 PRINTS PR00397 Sirohaem Fe-binding site signature 107 125 8.1E-7 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 104 299 1.3E-26 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 SUPERFAMILY SSF55124 18 81 3.43E-17 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 209 220 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 21 79 1.0E-15 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 SUPERFAMILY SSF56014 106 306 2.94E-36 T 13-10-2018 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 SUPERFAMILY SSF54862 150 230 5.98E-18 T 13-10-2018 CLOST_2027 359dbcebd53c19db0b88e731434fa425 333 Gene3D G3DSA:3.90.480.20 8 107 1.2E-13 T 13-10-2018 CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 SMART SM00487 356 561 0.0011 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 Gene3D G3DSA:3.30.870.10 8 208 9.6E-7 T 13-10-2018 CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 Gene3D G3DSA:3.40.50.300 588 853 2.8E-22 T 13-10-2018 CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 Pfam PF13091 PLD-like domain 36 182 6.5E-10 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 Pfam PF00176 SNF2 family N-terminal domain 383 614 6.5E-16 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 SMART SM00490 704 787 6.9E-6 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 SUPERFAMILY SSF52540 481 841 1.77E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 Pfam PF00271 Helicase conserved C-terminal domain 685 787 4.1E-7 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 Gene3D G3DSA:3.40.50.10810 382 587 3.7E-17 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily CLOST_1637 cc46454e9c3b948fa033dcd31581094c 856 SUPERFAMILY SSF52540 380 579 3.24E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 SUPERFAMILY SSF141000 608 698 5.36E-24 T 13-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Pfam PF02938 GAD domain 320 414 2.8E-21 T 13-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 SUPERFAMILY SSF55681 121 590 2.4E-107 T 13-10-2018 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 9 593 33.143 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 607 700 21.698 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Gene3D G3DSA:3.30.1360.30 284 428 8.6E-195 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 PRINTS PR01042 Aspartyl-tRNA synthetase signature 483 499 4.5E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 PRINTS PR01042 Aspartyl-tRNA synthetase signature 527 541 4.5E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 PRINTS PR01042 Aspartyl-tRNA synthetase signature 202 214 4.5E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 PRINTS PR01042 Aspartyl-tRNA synthetase signature 219 232 4.5E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 SUPERFAMILY SSF55261 301 427 8.83E-36 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 608 700 1.5E-23 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 9 590 1.1E-236 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Pfam PF01336 OB-fold nucleic acid binding domain 28 111 3.3E-15 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 624 695 8.5E-15 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 SUPERFAMILY SSF50249 7 119 1.2E-29 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Pfam PF00152 tRNA synthetases class II (D, K and N) 130 566 7.7E-110 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Gene3D G3DSA:1.10.20.60 605 698 1.7E-23 T 13-10-2018 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Gene3D G3DSA:2.40.50.140 3 115 3.7E-29 T 13-10-2018 CLOST_0018 6aaabd479a829e53af0c2060c964568c 700 Gene3D G3DSA:3.30.930.10 128 590 8.6E-195 T 13-10-2018 CLOST_1988 e274bdaeacd95acad674e22ef6065a5c 256 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 9 251 1.1E-86 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1988 e274bdaeacd95acad674e22ef6065a5c 256 Pfam PF00290 Tryptophan synthase alpha chain 9 251 5.8E-90 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1988 e274bdaeacd95acad674e22ef6065a5c 256 Gene3D G3DSA:3.20.20.70 1 256 8.4E-99 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1988 e274bdaeacd95acad674e22ef6065a5c 256 SUPERFAMILY SSF51366 1 250 1.13E-83 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CLOST_1988 e274bdaeacd95acad674e22ef6065a5c 256 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 9 254 34.75 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1106 04332fd9fa8bddf00c2ef09ebc4926f6 281 SUPERFAMILY SSF82549 2 278 6.02E-85 T 13-10-2018 CLOST_1106 04332fd9fa8bddf00c2ef09ebc4926f6 281 Gene3D G3DSA:3.30.1180.10 152 280 3.2E-33 T 13-10-2018 CLOST_1106 04332fd9fa8bddf00c2ef09ebc4926f6 281 Gene3D G3DSA:3.40.50.10170 1 149 1.0E-51 T 13-10-2018 CLOST_1106 04332fd9fa8bddf00c2ef09ebc4926f6 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 2 276 2.0E-90 T 13-10-2018 IPR003797 DegV CLOST_1106 04332fd9fa8bddf00c2ef09ebc4926f6 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 277 2.3E-84 T 13-10-2018 IPR003797 DegV CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 Gene3D G3DSA:3.40.50.720 4 250 1.7E-75 T 13-10-2018 CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 139 156 - T 13-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 PIRSF PIRSF000161 1 253 1.3E-73 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 116 250 6.4E-44 T 13-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 113 3.4E-20 T 13-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 252 28.851 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 SUPERFAMILY SSF55347 115 223 5.23E-30 T 13-10-2018 CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 SUPERFAMILY SSF51735 2 252 2.12E-29 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 Gene3D G3DSA:3.30.360.10 115 221 1.7E-75 T 13-10-2018 CLOST_1829 b4d7a3e6e3df43444973911c34771120 253 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 2 252 1.2E-58 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 SUPERFAMILY SSF142019 3 166 1.44E-41 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 SUPERFAMILY SSF51230 377 432 2.09E-5 T 13-10-2018 IPR011053 Single hybrid motif CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 Pfam PF10531 SLBB domain 164 209 8.3E-9 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 254 265 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 SUPERFAMILY SSF142984 163 215 4.05E-9 T 13-10-2018 CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 PIRSF PIRSF036408 1 442 1.3E-184 T 13-10-2018 IPR017054 Propanediol utilization protein, PduS, predicted CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 Pfam PF13375 RnfC Barrel sandwich hybrid domain 381 438 2.6E-14 T 13-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 Gene3D G3DSA:2.40.50.100 374 443 2.8E-5 T 13-10-2018 CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 7 151 2.0E-44 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 Gene3D G3DSA:3.40.50.11540 12 120 8.6E-14 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 Pfam PF13534 4Fe-4S dicluster domain 253 313 6.0E-8 T 13-10-2018 CLOST_0260 24ed98dc4b91897a5c7a466b46874286 445 SUPERFAMILY SSF46548 242 329 1.01E-9 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_2002 e8508e9b2e23c89f1e99981a82474e89 173 Gene3D G3DSA:3.30.1340.20 65 173 6.6E-35 T 13-10-2018 IPR035922 3H domain superfamily CLOST_2002 e8508e9b2e23c89f1e99981a82474e89 173 PIRSF PIRSF037847 1 172 2.2E-63 T 13-10-2018 IPR026043 Transcription repressor NadR CLOST_2002 e8508e9b2e23c89f1e99981a82474e89 173 SUPERFAMILY SSF75500 67 171 3.79E-30 T 13-10-2018 IPR035922 3H domain superfamily CLOST_2002 e8508e9b2e23c89f1e99981a82474e89 173 Pfam PF02829 3H domain 72 169 3.8E-33 T 13-10-2018 IPR004173 3H domain GO:0036094 CLOST_2002 e8508e9b2e23c89f1e99981a82474e89 173 Gene3D G3DSA:1.10.10.10 1 63 4.9E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2002 e8508e9b2e23c89f1e99981a82474e89 173 Pfam PF08279 HTH domain 6 59 8.1E-14 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 CLOST_2002 e8508e9b2e23c89f1e99981a82474e89 173 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 80 170 4.0E-17 T 13-10-2018 IPR004173 3H domain GO:0036094 CLOST_2002 e8508e9b2e23c89f1e99981a82474e89 173 SUPERFAMILY SSF46785 2 60 8.46E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1172 56cdd9026b89bbcfec227afc43996807 123 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 122 3.2E-46 T 13-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CLOST_1172 56cdd9026b89bbcfec227afc43996807 123 SUPERFAMILY SSF51230 2 122 2.99E-40 T 13-10-2018 IPR011053 Single hybrid motif CLOST_1172 56cdd9026b89bbcfec227afc43996807 123 Pfam PF01597 Glycine cleavage H-protein 7 121 1.6E-41 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate CLOST_1172 56cdd9026b89bbcfec227afc43996807 123 Gene3D G3DSA:2.40.50.100 1 123 8.9E-45 T 13-10-2018 CLOST_1172 56cdd9026b89bbcfec227afc43996807 123 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CLOST_1172 56cdd9026b89bbcfec227afc43996807 123 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 122 33.816 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CLOST_0485 b5a45ac1d18f8de4b6536002d859257e 400 Gene3D G3DSA:2.170.120.30 35 134 3.9E-6 T 13-10-2018 CLOST_0485 b5a45ac1d18f8de4b6536002d859257e 400 Gene3D G3DSA:2.170.120.40 222 307 8.4E-7 T 13-10-2018 CLOST_0485 b5a45ac1d18f8de4b6536002d859257e 400 Gene3D G3DSA:2.170.120.40 135 220 7.8E-12 T 13-10-2018 CLOST_0485 b5a45ac1d18f8de4b6536002d859257e 400 Pfam PF07949 YbbR-like protein 135 203 4.4E-11 T 13-10-2018 IPR012505 YbbR-like CLOST_0485 b5a45ac1d18f8de4b6536002d859257e 400 Gene3D G3DSA:2.170.120.30 314 400 4.5E-5 T 13-10-2018 CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 Pfam PF07729 FCD domain 88 211 2.5E-26 T 13-10-2018 IPR011711 GntR, C-terminal CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 SMART SM00345 20 78 2.2E-17 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 1.8E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 1.8E-6 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 SUPERFAMILY SSF48008 83 219 1.28E-30 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 SMART SM00895 88 212 3.9E-23 T 13-10-2018 IPR011711 GntR, C-terminal CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 Gene3D G3DSA:1.20.120.530 82 223 2.4E-30 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 SUPERFAMILY SSF46785 14 106 8.29E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 Gene3D G3DSA:1.10.10.10 13 79 2.1E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 49 6.8E-6 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 68 6.8E-6 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CLOST_0932 a29d969340806c8bffdb0aafb65577d2 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 1.3E-18 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_1427 bf1034a5affc11ecc5aa4c8d2a5866fe 251 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 63 243 9.0E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_1427 bf1034a5affc11ecc5aa4c8d2a5866fe 251 SUPERFAMILY SSF161098 54 236 1.05E-20 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1427 bf1034a5affc11ecc5aa4c8d2a5866fe 251 Gene3D G3DSA:1.10.3720.10 41 246 4.5E-21 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 1.1E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 SMART SM00448 2 115 3.5E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 Gene3D G3DSA:3.40.50.12740 2 213 6.1E-63 T 13-10-2018 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 Pfam PF00072 Response regulator receiver domain 5 115 1.7E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.5E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.5E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.5E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 SUPERFAMILY SSF46894 145 212 2.75E-20 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 SUPERFAMILY SSF52172 1 127 2.85E-33 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_0510 86813bbba5dc8e9ea8018f208f6dae8a 213 SMART SM00421 150 207 7.8E-21 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_0823 f043d4a4be81ea07ca22a6225867d516 495 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 8 318 1.0E-60 T 13-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CLOST_0823 f043d4a4be81ea07ca22a6225867d516 495 Gene3D G3DSA:3.40.640.10 7 284 2.3E-99 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0823 f043d4a4be81ea07ca22a6225867d516 495 SUPERFAMILY SSF53383 8 378 1.18E-70 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0823 f043d4a4be81ea07ca22a6225867d516 495 Gene3D G3DSA:3.90.105.10 429 481 5.8E-17 T 13-10-2018 CLOST_0823 f043d4a4be81ea07ca22a6225867d516 495 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 392 472 3.6E-12 T 13-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 Gene3D G3DSA:3.30.450.40 128 311 1.7E-16 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 Pfam PF00512 His Kinase A (phospho-acceptor) domain 469 528 4.2E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 SUPERFAMILY SSF55874 575 728 2.23E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 Pfam PF13188 PAS domain 316 371 1.7E-6 T 13-10-2018 IPR000014 PAS domain CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 SMART SM00387 616 728 1.4E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 Pfam PF01590 GAF domain 159 300 4.5E-5 T 13-10-2018 IPR003018 GAF domain GO:0005515 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 312 438 1.4E-10 T 13-10-2018 IPR000014 PAS domain CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 Gene3D G3DSA:3.30.450.20 312 428 5.2E-15 T 13-10-2018 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 SUPERFAMILY SSF47384 462 521 2.35E-6 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 Gene3D G3DSA:1.10.287.130 443 570 6.0E-23 T 13-10-2018 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 620 727 2.7E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 SUPERFAMILY SSF55785 307 429 4.19E-12 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 PRINTS PR00344 Bacterial sensor protein C-terminal signature 676 686 7.9E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 PRINTS PR00344 Bacterial sensor protein C-terminal signature 658 672 7.9E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 PRINTS PR00344 Bacterial sensor protein C-terminal signature 714 727 7.9E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 PRINTS PR00344 Bacterial sensor protein C-terminal signature 689 707 7.9E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 SUPERFAMILY SSF55781 143 303 2.33E-11 T 13-10-2018 CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 SMART SM00091 315 386 0.0039 T 13-10-2018 IPR000014 PAS domain CLOST_0885 1657527419036c8efd14afdd3c48ee0a 728 Gene3D G3DSA:3.30.565.10 578 728 2.1E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1696 5a921b9b42a8325002bd2eb114eb6a72 348 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 1 347 33.272 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CLOST_1696 5a921b9b42a8325002bd2eb114eb6a72 348 SUPERFAMILY SSF51717 10 202 4.39E-11 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1696 5a921b9b42a8325002bd2eb114eb6a72 348 Gene3D G3DSA:3.30.413.10 255 348 3.7E-35 T 13-10-2018 CLOST_1696 5a921b9b42a8325002bd2eb114eb6a72 348 Pfam PF04551 GcpE protein 6 346 6.3E-140 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CLOST_1696 5a921b9b42a8325002bd2eb114eb6a72 348 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 3 345 5.6E-127 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CLOST_1696 5a921b9b42a8325002bd2eb114eb6a72 348 PIRSF PIRSF004640 1 348 1.3E-146 T 13-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CLOST_1696 5a921b9b42a8325002bd2eb114eb6a72 348 SUPERFAMILY SSF56014 260 346 2.53E-10 T 13-10-2018 CLOST_1696 5a921b9b42a8325002bd2eb114eb6a72 348 Gene3D G3DSA:3.20.20.20 1 254 5.1E-107 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1591 9925c22d1c60e9ce8b5fb3ffe3505068 246 Gene3D G3DSA:3.40.50.1860 120 233 3.8E-70 T 13-10-2018 CLOST_1591 9925c22d1c60e9ce8b5fb3ffe3505068 246 TIGRFAM TIGR00035 asp_race: aspartate racemase 17 243 1.6E-50 T 13-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CLOST_1591 9925c22d1c60e9ce8b5fb3ffe3505068 246 SUPERFAMILY SSF53681 17 127 2.13E-30 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_1591 9925c22d1c60e9ce8b5fb3ffe3505068 246 Pfam PF01177 Asp/Glu/Hydantoin racemase 22 241 4.0E-48 T 13-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_1591 9925c22d1c60e9ce8b5fb3ffe3505068 246 SUPERFAMILY SSF53681 134 243 4.19E-20 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_1591 9925c22d1c60e9ce8b5fb3ffe3505068 246 Gene3D G3DSA:3.40.50.1860 19 239 3.8E-70 T 13-10-2018 CLOST_1285 b594ab9faadf331f08312692e6b8b09a 199 Pfam PF03956 Lysine exporter LysO 9 196 4.0E-59 T 13-10-2018 IPR005642 Lysine exporter LysO CLOST_1285 b594ab9faadf331f08312692e6b8b09a 199 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 38 181 2.0E-29 T 13-10-2018 IPR005642 Lysine exporter LysO CLOST_2331 43e893ad948861c28007d3d1d230a3d7 126 Pfam PF02561 Flagellar protein FliS 7 119 3.7E-38 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 CLOST_2331 43e893ad948861c28007d3d1d230a3d7 126 PIRSF PIRSF039090 1 126 4.6E-35 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 CLOST_2331 43e893ad948861c28007d3d1d230a3d7 126 SUPERFAMILY SSF101116 4 121 1.16E-36 T 13-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 CLOST_2331 43e893ad948861c28007d3d1d230a3d7 126 TIGRFAM TIGR00208 fliS: flagellar protein FliS 2 119 4.1E-32 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 CLOST_2331 43e893ad948861c28007d3d1d230a3d7 126 Gene3D G3DSA:1.20.120.340 1 121 1.3E-38 T 13-10-2018 CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 SMART SM00382 30 218 4.8E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 Gene3D G3DSA:3.40.50.300 2 240 2.7E-72 T 13-10-2018 CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 SUPERFAMILY SSF52540 6 245 3.43E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 Pfam PF00005 ABC transporter 22 163 1.0E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 SUPERFAMILY SSF50331 238 351 1.08E-12 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 Pfam PF08402 TOBE domain 278 351 1.3E-8 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 Gene3D G3DSA:2.40.50.100 281 319 9.7E-6 T 13-10-2018 CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 Gene3D G3DSA:2.40.50.140 241 280 9.7E-6 T 13-10-2018 CLOST_1201 74afd4bd500883ce708520cc420b0aa2 356 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 36 350 4.3E-116 T 13-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CLOST_1095 5f4c33945046d0c08bc952f0181dd85e 554 Gene3D G3DSA:3.40.50.300 226 498 8.0E-56 T 13-10-2018 CLOST_1095 5f4c33945046d0c08bc952f0181dd85e 554 SUPERFAMILY SSF55186 66 235 5.41E-30 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 CLOST_1095 5f4c33945046d0c08bc952f0181dd85e 554 Gene3D G3DSA:3.30.980.10 67 205 2.1E-23 T 13-10-2018 CLOST_1095 5f4c33945046d0c08bc952f0181dd85e 554 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 289 488 7.0E-16 T 13-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 CLOST_1095 5f4c33945046d0c08bc952f0181dd85e 554 SUPERFAMILY SSF52540 285 539 1.43E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1654 6016741245517b216854c6295e4b378a 320 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 6 315 34.356 T 13-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CLOST_1654 6016741245517b216854c6295e4b378a 320 Pfam PF02650 WhiA C-terminal HTH domain 229 312 1.8E-37 T 13-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal CLOST_1654 6016741245517b216854c6295e4b378a 320 Gene3D G3DSA:1.10.10.10 225 317 4.0E-38 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1654 6016741245517b216854c6295e4b378a 320 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 24 110 3.2E-27 T 13-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CLOST_1654 6016741245517b216854c6295e4b378a 320 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 7 312 5.8E-105 T 13-10-2018 IPR033981 Sporulation regulator WhiA-like CLOST_1654 6016741245517b216854c6295e4b378a 320 Pfam PF14527 WhiA LAGLIDADG-like domain 135 226 1.7E-33 T 13-10-2018 IPR039518 WhiA, LAGLIDADG-like domain CLOST_1654 6016741245517b216854c6295e4b378a 320 Gene3D G3DSA:3.10.28.10 1 224 1.3E-63 T 13-10-2018 IPR027434 Homing endonuclease CLOST_1654 6016741245517b216854c6295e4b378a 320 SUPERFAMILY SSF55608 124 230 6.8E-18 T 13-10-2018 IPR027434 Homing endonuclease CLOST_1227 87195625673ffad81b16001e277cfe1c 477 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 41 473 3.4E-154 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CLOST_1227 87195625673ffad81b16001e277cfe1c 477 Pfam PF04055 Radical SAM superfamily 189 360 1.0E-31 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1227 87195625673ffad81b16001e277cfe1c 477 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 41 473 5.3E-166 T 13-10-2018 CLOST_1227 87195625673ffad81b16001e277cfe1c 477 Gene3D G3DSA:3.80.30.20 184 417 2.2E-96 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1227 87195625673ffad81b16001e277cfe1c 477 Gene3D G3DSA:3.40.50.12160 40 167 9.6E-33 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily CLOST_1227 87195625673ffad81b16001e277cfe1c 477 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 39 477 71.466 T 13-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CLOST_1227 87195625673ffad81b16001e277cfe1c 477 Pfam PF00919 Uncharacterized protein family UPF0004 41 141 1.4E-27 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CLOST_1227 87195625673ffad81b16001e277cfe1c 477 Pfam PF01938 TRAM domain 419 476 1.3E-12 T 13-10-2018 IPR002792 TRAM domain CLOST_1227 87195625673ffad81b16001e277cfe1c 477 SMART SM00729 185 403 7.0E-64 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1227 87195625673ffad81b16001e277cfe1c 477 SUPERFAMILY SSF102114 181 407 1.29E-61 T 13-10-2018 CLOST_1227 87195625673ffad81b16001e277cfe1c 477 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 189 209 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CLOST_2550 55388b79fd796e44220566b91fecbf77 402 Gene3D G3DSA:2.40.50.100 58 250 2.3E-47 T 13-10-2018 CLOST_2550 55388b79fd796e44220566b91fecbf77 402 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 307 8.8E-18 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CLOST_2550 55388b79fd796e44220566b91fecbf77 402 Gene3D G3DSA:1.10.287.470 92 215 2.3E-47 T 13-10-2018 CLOST_2550 55388b79fd796e44220566b91fecbf77 402 SUPERFAMILY SSF111369 50 306 5.49E-13 T 13-10-2018 CLOST_2550 55388b79fd796e44220566b91fecbf77 402 Gene3D G3DSA:2.40.420.20 44 370 2.3E-47 T 13-10-2018 CLOST_2550 55388b79fd796e44220566b91fecbf77 402 Gene3D G3DSA:2.40.30.170 47 327 2.3E-47 T 13-10-2018 CLOST_0999 9b5203e657c98951963d202f9077c140 498 Gene3D G3DSA:3.40.50.10090 423 498 6.6E-13 T 13-10-2018 CLOST_0999 9b5203e657c98951963d202f9077c140 498 Gene3D G3DSA:3.40.1010.10 2 119 1.1E-41 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 CLOST_0999 9b5203e657c98951963d202f9077c140 498 Gene3D G3DSA:3.40.50.10090 284 415 7.9E-26 T 13-10-2018 CLOST_0999 9b5203e657c98951963d202f9077c140 498 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 215 3.4E-45 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 CLOST_0999 9b5203e657c98951963d202f9077c140 498 Pfam PF02602 Uroporphyrinogen-III synthase HemD 266 489 1.7E-54 T 13-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0999 9b5203e657c98951963d202f9077c140 498 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 239 5.1E-92 T 13-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 CLOST_0999 9b5203e657c98951963d202f9077c140 498 SUPERFAMILY SSF69618 253 492 2.22E-59 T 13-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0999 9b5203e657c98951963d202f9077c140 498 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 CLOST_0999 9b5203e657c98951963d202f9077c140 498 Gene3D G3DSA:3.30.950.10 120 268 5.8E-45 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 CLOST_0999 9b5203e657c98951963d202f9077c140 498 SUPERFAMILY SSF53790 2 254 2.88E-75 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 CLOST_0999 9b5203e657c98951963d202f9077c140 498 PIRSF PIRSF036426 1 256 6.2E-98 T 13-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Gene3D G3DSA:3.30.980.10 566 701 3.2E-53 T 13-10-2018 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Gene3D G3DSA:3.30.54.20 628 681 3.2E-53 T 13-10-2018 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Gene3D G3DSA:2.40.30.130 481 556 9.8E-9 T 13-10-2018 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Gene3D G3DSA:3.30.930.10 4 242 1.7E-104 T 13-10-2018 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 859 0.0 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Gene3D G3DSA:3.10.310.40 768 878 5.5E-32 T 13-10-2018 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 SMART SM00863 657 700 6.0E-23 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 177.133 T 13-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Pfam PF01411 tRNA synthetases class II (A) 8 559 2.5E-207 T 13-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 SUPERFAMILY SSF50447 458 556 1.62E-15 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 3.7E-29 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 3.7E-29 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 3.7E-29 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 3.7E-29 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 3.7E-29 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 SUPERFAMILY SSF55186 556 715 6.54E-54 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 SUPERFAMILY SSF101353 246 440 3.66E-68 T 13-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 657 700 4.2E-20 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 SUPERFAMILY SSF55681 5 245 7.12E-98 T 13-10-2018 CLOST_1491 2f23dadbc06dd9eb3f3420de1dd9b491 882 Pfam PF02272 DHHA1 domain 738 871 3.2E-23 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CLOST_1083 daf9ea9a135bbb9acafe280be4b8bab6 191 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 6 165 33.475 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CLOST_1083 daf9ea9a135bbb9acafe280be4b8bab6 191 SUPERFAMILY SSF55068 4 171 1.83E-63 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CLOST_1083 daf9ea9a135bbb9acafe280be4b8bab6 191 Pfam PF01625 Peptide methionine sulfoxide reductase 8 159 3.4E-55 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CLOST_1083 daf9ea9a135bbb9acafe280be4b8bab6 191 Gene3D G3DSA:3.30.1060.10 1 166 1.1E-57 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CLOST_1083 daf9ea9a135bbb9acafe280be4b8bab6 191 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 158 1.6E-53 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CLOST_0294 6c9ab4b900000122e22e85550144f7a6 231 Gene3D G3DSA:3.20.20.70 14 229 6.6E-20 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0294 6c9ab4b900000122e22e85550144f7a6 231 SUPERFAMILY SSF102114 21 205 1.16E-20 T 13-10-2018 CLOST_0294 6c9ab4b900000122e22e85550144f7a6 231 Pfam PF04055 Radical SAM superfamily 27 184 1.2E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1742 08b3699efe9fd8b8819c9dfe69fe1c64 99 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 29 45 3.4E-10 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CLOST_1742 08b3699efe9fd8b8819c9dfe69fe1c64 99 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 63 79 3.4E-10 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CLOST_1742 08b3699efe9fd8b8819c9dfe69fe1c64 99 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 84 97 3.4E-10 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CLOST_1742 08b3699efe9fd8b8819c9dfe69fe1c64 99 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 22 99 6.9E-21 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CLOST_1742 08b3699efe9fd8b8819c9dfe69fe1c64 99 Pfam PF02049 Flagellar hook-basal body complex protein FliE 21 99 1.3E-23 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CLOST_1742 08b3699efe9fd8b8819c9dfe69fe1c64 99 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 99 16.127 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 SUPERFAMILY SSF52540 5 168 1.69E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 Gene3D G3DSA:3.40.50.300 171 347 1.3E-53 T 13-10-2018 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 433 7.6E-179 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 1.1E-35 T 13-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 Pfam PF01926 50S ribosome-binding GTPase 177 295 4.0E-27 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 Pfam PF01926 50S ribosome-binding GTPase 5 120 1.9E-27 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 146 6.5E-25 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 339 1.5E-30 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 1.8E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 1.8E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 Gene3D G3DSA:3.40.50.300 1 163 9.4E-45 T 13-10-2018 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 Gene3D G3DSA:3.30.300.20 353 436 3.5E-35 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 PIRSF PIRSF006485 1 438 1.4E-177 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 Hamap MF_00195 GTPase Der [der]. 2 436 41.229 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 CLOST_1885 bdd9c71b35d084c7dcc24391bb6aad4a 438 SUPERFAMILY SSF52540 138 436 5.22E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Gene3D G3DSA:3.40.50.11180 40 323 1.0E-64 T 13-10-2018 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SMART SM01058 490 588 8.1E-39 T 13-10-2018 IPR003711 CarD-like/TRCF domain CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SUPERFAMILY SSF52540 664 936 1.67E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SMART SM00982 1015 1113 9.4E-34 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 48 1124 27.397 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1089 0.0 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Pfam PF00271 Helicase conserved C-terminal domain 817 921 4.4E-17 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Gene3D G3DSA:3.40.50.300 490 1001 1.7E-236 T 13-10-2018 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SMART SM00487 612 804 2.0E-32 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Gene3D G3DSA:3.30.2060.10 141 226 1.0E-64 T 13-10-2018 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SUPERFAMILY SSF52540 17 360 2.3E-78 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Pfam PF03461 TRCF domain 1016 1097 1.6E-26 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Pfam PF02559 CarD-like/TRCF domain 491 587 5.6E-29 T 13-10-2018 IPR003711 CarD-like/TRCF domain CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SUPERFAMILY SSF141259 482 560 5.1E-19 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Pfam PF00270 DEAD/DEAH box helicase 636 776 3.8E-18 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Gene3D G3DSA:3.40.50.300 554 793 1.7E-236 T 13-10-2018 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Gene3D G3DSA:2.30.30.840 494 553 1.7E-236 T 13-10-2018 CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SUPERFAMILY SSF143517 1001 1101 1.29E-31 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SUPERFAMILY SSF52540 369 477 2.39E-11 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 SMART SM00490 838 922 6.2E-19 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0475 7e3e2251100b5ab889262bc602a81c41 1130 Gene3D G3DSA:3.90.1150.50 1011 1128 2.6E-30 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain CLOST_1380 36cccbd0ca219c6be52ac50ace5ad5d3 486 Gene3D G3DSA:3.40.50.300 242 486 7.8E-44 T 13-10-2018 CLOST_1380 36cccbd0ca219c6be52ac50ace5ad5d3 486 Pfam PF00488 MutS domain V 286 409 2.4E-24 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_1380 36cccbd0ca219c6be52ac50ace5ad5d3 486 SMART SM00534 282 485 8.9E-13 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_1380 36cccbd0ca219c6be52ac50ace5ad5d3 486 SUPERFAMILY SSF48334 60 239 3.53E-9 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily CLOST_1380 36cccbd0ca219c6be52ac50ace5ad5d3 486 SUPERFAMILY SSF52540 243 406 3.33E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0079 d048f2ad33a926443d3fe684ce0f2b88 218 SUPERFAMILY SSF52242 74 215 1.57E-43 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0079 d048f2ad33a926443d3fe684ce0f2b88 218 SUPERFAMILY SSF47644 4 88 2.88E-20 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0079 d048f2ad33a926443d3fe684ce0f2b88 218 SMART SM01018 6 89 6.7E-24 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0079 d048f2ad33a926443d3fe684ce0f2b88 218 Pfam PF02607 B12 binding domain 9 81 1.2E-12 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0079 d048f2ad33a926443d3fe684ce0f2b88 218 Gene3D G3DSA:3.40.50.280 87 218 5.1E-47 T 13-10-2018 CLOST_0079 d048f2ad33a926443d3fe684ce0f2b88 218 Gene3D G3DSA:1.10.1240.10 4 86 9.6E-22 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0079 d048f2ad33a926443d3fe684ce0f2b88 218 Pfam PF02310 B12 binding domain 96 208 7.6E-23 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0257 542a47cd12a7b46ec6e4c1d3c8857061 149 SUPERFAMILY SSF51182 40 146 1.89E-21 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0257 542a47cd12a7b46ec6e4c1d3c8857061 149 Pfam PF06249 Ethanolamine utilisation protein EutQ 4 148 8.2E-49 T 13-10-2018 IPR010424 Ethanolamine utilisation EutQ CLOST_0257 542a47cd12a7b46ec6e4c1d3c8857061 149 Gene3D G3DSA:2.60.120.10 10 149 4.0E-44 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 Pfam PF00455 DeoR C terminal sensor domain 77 231 3.2E-46 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 SUPERFAMILY SSF100950 76 232 2.26E-29 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 SMART SM01134 73 233 8.5E-63 T 13-10-2018 CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 13-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 2.1E-16 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-8 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-8 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 SMART SM00420 6 58 1.2E-19 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 Gene3D G3DSA:1.10.10.10 1 56 1.4E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0672 814c716e17dafeaa2aea8b6102c8a428 254 SUPERFAMILY SSF46785 6 59 7.94E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1162 0c35e86fa10101b3406b57c97e3e4406 558 Pfam PF01268 Formate--tetrahydrofolate ligase 4 558 1.7E-274 T 13-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CLOST_1162 0c35e86fa10101b3406b57c97e3e4406 558 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 13-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CLOST_1162 0c35e86fa10101b3406b57c97e3e4406 558 Gene3D G3DSA:3.30.1510.10 130 248 1.1E-210 T 13-10-2018 CLOST_1162 0c35e86fa10101b3406b57c97e3e4406 558 Gene3D G3DSA:3.10.410.10 445 534 2.9E-38 T 13-10-2018 CLOST_1162 0c35e86fa10101b3406b57c97e3e4406 558 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 3 558 49.569 T 13-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CLOST_1162 0c35e86fa10101b3406b57c97e3e4406 558 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 104 114 - T 13-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CLOST_1162 0c35e86fa10101b3406b57c97e3e4406 558 Gene3D G3DSA:3.40.50.300 8 439 1.1E-210 T 13-10-2018 CLOST_1162 0c35e86fa10101b3406b57c97e3e4406 558 SUPERFAMILY SSF52540 6 556 5.65E-247 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1833 4306b746012173cbd7b3ff96cbe671ac 513 SUPERFAMILY SSF55781 17 167 1.1E-5 T 13-10-2018 CLOST_1833 4306b746012173cbd7b3ff96cbe671ac 513 Gene3D G3DSA:3.30.450.40 350 505 1.8E-5 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_1833 4306b746012173cbd7b3ff96cbe671ac 513 SUPERFAMILY SSF55781 186 347 6.76E-5 T 13-10-2018 CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 SUPERFAMILY SSF52540 7 253 4.69E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 312 6.5E-19 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 SUPERFAMILY SSF52540 320 543 3.26E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 294 2.3E-13 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 Pfam PF00005 ABC transporter 26 182 1.4E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 Gene3D G3DSA:3.40.50.300 317 545 1.0E-61 T 13-10-2018 CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 Gene3D G3DSA:3.40.50.300 4 316 1.2E-79 T 13-10-2018 CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 ProSitePatterns PS00211 ABC transporters family signature. 463 477 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 Pfam PF00005 ABC transporter 342 489 2.9E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 SMART SM00382 35 232 6.8E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 SMART SM00382 349 539 1.2E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2267 611465f6e226d0a57e419e1816a89f00 549 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0979 6e689451bca66d3cca8d8260620806b0 242 SUPERFAMILY SSF56784 1 229 1.11E-27 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_0979 6e689451bca66d3cca8d8260620806b0 242 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 194 5.3E-31 T 13-10-2018 CLOST_0979 6e689451bca66d3cca8d8260620806b0 242 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 5 205 1.3E-49 T 13-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CLOST_0979 6e689451bca66d3cca8d8260620806b0 242 Gene3D G3DSA:1.20.1440.100 17 93 1.3E-35 T 13-10-2018 CLOST_0979 6e689451bca66d3cca8d8260620806b0 242 Gene3D G3DSA:3.40.50.1000 6 207 1.3E-35 T 13-10-2018 IPR023214 HAD superfamily CLOST_0979 6e689451bca66d3cca8d8260620806b0 242 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 192 6.1E-20 T 13-10-2018 CLOST_0578 ea5a1d3460763b6cba3f9f52dc09fb8b 339 SUPERFAMILY SSF54197 182 335 2.47E-32 T 13-10-2018 IPR036265 HIT-like superfamily CLOST_0578 ea5a1d3460763b6cba3f9f52dc09fb8b 339 PIRSF PIRSF000808 1 336 2.2E-87 T 13-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 CLOST_0578 ea5a1d3460763b6cba3f9f52dc09fb8b 339 SUPERFAMILY SSF54197 2 180 5.86E-41 T 13-10-2018 IPR036265 HIT-like superfamily CLOST_0578 ea5a1d3460763b6cba3f9f52dc09fb8b 339 Gene3D G3DSA:3.30.428.10 3 331 9.1E-101 T 13-10-2018 IPR036265 HIT-like superfamily CLOST_0578 ea5a1d3460763b6cba3f9f52dc09fb8b 339 Gene3D G3DSA:3.30.428.10 46 178 9.1E-101 T 13-10-2018 IPR036265 HIT-like superfamily CLOST_0578 ea5a1d3460763b6cba3f9f52dc09fb8b 339 Pfam PF16268 Domain of unknown function (DUF4921) 123 336 1.2E-15 T 13-10-2018 IPR032576 Domain of unknown function DUF4921 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 SMART SM00363 8 65 1.5E-11 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 Gene3D G3DSA:3.30.70.1560 135 218 1.9E-55 T 13-10-2018 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 Gene3D G3DSA:3.10.290.10 7 63 2.2E-18 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 Gene3D G3DSA:3.30.70.580 68 236 1.9E-55 T 13-10-2018 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 Pfam PF00849 RNA pseudouridylate synthase 68 201 5.8E-18 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 SUPERFAMILY SSF55120 67 236 2.88E-42 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 72 233 2.5E-43 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 Pfam PF01479 S4 domain 8 54 1.5E-10 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 106 120 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CLOST_1194 c15cfa8be5b1bc22e7b585062e908ba0 243 SUPERFAMILY SSF55174 5 100 9.13E-17 T 13-10-2018 CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 SUPERFAMILY SSF46604 87 131 1.41E-6 T 13-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 Gene3D G3DSA:1.20.5.440 89 132 3.3E-10 T 13-10-2018 CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 Gene3D G3DSA:2.60.15.10 1 88 2.2E-27 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 SUPERFAMILY SSF51344 3 84 2.88E-22 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 21.205 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 87 131 1.2E-9 T 13-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 88 8.0E-9 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 130 9.5E-30 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2115 1a3584bf3f77686a00499e2f81996765 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 82 2.1E-26 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_1920 6bc0d700f4d719c32ceb1c3a35aad25c 182 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 168 6.9E-57 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CLOST_1920 6bc0d700f4d719c32ceb1c3a35aad25c 182 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 144 1.0E-43 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CLOST_1920 6bc0d700f4d719c32ceb1c3a35aad25c 182 Gene3D G3DSA:1.20.1200.10 13 180 8.8E-56 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CLOST_1920 6bc0d700f4d719c32ceb1c3a35aad25c 182 SUPERFAMILY SSF89028 1 166 5.3E-56 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CLOST_1920 6bc0d700f4d719c32ceb1c3a35aad25c 182 Pfam PF01923 Cobalamin adenosyltransferase 3 164 6.2E-58 T 13-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CLOST_0875 91701ecbe5f468a52535bd28aad75ba5 236 Pfam PF03692 Putative zinc- or iron-chelating domain 27 108 4.6E-11 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein CLOST_0888 42b272480163746b5b1ba38d9e9c8ac9 230 SUPERFAMILY SSF69572 4 226 1.18E-65 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 CLOST_0888 42b272480163746b5b1ba38d9e9c8ac9 230 Gene3D G3DSA:3.40.50.720 2 230 5.2E-54 T 13-10-2018 CLOST_0888 42b272480163746b5b1ba38d9e9c8ac9 230 Pfam PF00899 ThiF family 15 227 1.2E-42 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 Gene3D G3DSA:3.30.930.10 106 425 1.8E-123 T 13-10-2018 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 SUPERFAMILY SSF46589 1 113 4.6E-25 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 41.574 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 PIRSF PIRSF001529 1 425 3.7E-179 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 224 400 8.7E-34 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 5.2E-170 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 7.9E-26 T 13-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 Gene3D G3DSA:1.10.287.40 1 105 4.4E-21 T 13-10-2018 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 7.1E-32 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 7.1E-32 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 7.1E-32 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 7.1E-32 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 7.1E-32 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CLOST_0051 2b7de2145c13c5a4e41d59c333be2380 425 SUPERFAMILY SSF55681 117 423 2.3E-100 T 13-10-2018 CLOST_0671 df2e5519766ef87150b69be4bf2b3500 374 Pfam PF07687 Peptidase dimerisation domain 186 276 2.0E-14 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain CLOST_0671 df2e5519766ef87150b69be4bf2b3500 374 Gene3D G3DSA:3.30.70.360 180 291 7.1E-104 T 13-10-2018 CLOST_0671 df2e5519766ef87150b69be4bf2b3500 374 SUPERFAMILY SSF55031 184 292 1.02E-19 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain CLOST_0671 df2e5519766ef87150b69be4bf2b3500 374 SUPERFAMILY SSF53187 5 372 1.57E-53 T 13-10-2018 CLOST_0671 df2e5519766ef87150b69be4bf2b3500 374 Pfam PF01546 Peptidase family M20/M25/M40 72 371 2.9E-21 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 CLOST_0671 df2e5519766ef87150b69be4bf2b3500 374 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 5 371 1.7E-86 T 13-10-2018 IPR010162 Peptidase M20B, peptidase T-like CLOST_0671 df2e5519766ef87150b69be4bf2b3500 374 Gene3D G3DSA:3.40.630.10 13 366 7.1E-104 T 13-10-2018 CLOST_0850 40f4763c25c704584947db083f1bd716 304 Gene3D G3DSA:1.10.8.300 190 297 3.1E-33 T 13-10-2018 CLOST_0850 40f4763c25c704584947db083f1bd716 304 SUPERFAMILY SSF52540 4 273 1.87E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0850 40f4763c25c704584947db083f1bd716 304 Gene3D G3DSA:3.40.50.300 13 179 1.9E-48 T 13-10-2018 CLOST_0850 40f4763c25c704584947db083f1bd716 304 PIRSF PIRSF002849 1 303 5.5E-131 T 13-10-2018 CLOST_0850 40f4763c25c704584947db083f1bd716 304 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 32 162 2.4E-64 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 Pfam PF02541 Ppx/GppA phosphatase family 23 303 1.9E-61 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 SUPERFAMILY SSF53067 4 124 2.54E-32 T 13-10-2018 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 4 302 1.0E-93 T 13-10-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 Gene3D G3DSA:3.30.420.150 109 301 5.1E-57 T 13-10-2018 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 SUPERFAMILY SSF109604 314 499 1.82E-30 T 13-10-2018 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 PIRSF PIRSF001267 1 492 9.7E-82 T 13-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 Gene3D G3DSA:1.10.3210.10 306 499 9.7E-31 T 13-10-2018 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 SUPERFAMILY SSF53067 128 304 6.76E-44 T 13-10-2018 CLOST_0904 3d943073ab18ca8749d67602f0f8c592 500 Gene3D G3DSA:3.30.420.40 1 108 4.7E-29 T 13-10-2018 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Gene3D G3DSA:3.30.70.20 569 624 6.6E-15 T 13-10-2018 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Gene3D G3DSA:3.10.20.600 371 465 8.4E-35 T 13-10-2018 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 SUPERFAMILY SSF140490 464 566 2.22E-38 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Gene3D G3DSA:3.40.30.10 31 128 1.6E-24 T 13-10-2018 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 607 618 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 SUPERFAMILY SSF54862 567 623 8.87E-17 T 13-10-2018 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 187 358 2.7E-48 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 SUPERFAMILY SSF52833 35 126 8.28E-22 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Gene3D G3DSA:1.20.1440.230 466 566 3.9E-34 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 469 553 4.8E-33 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Pfam PF14697 4Fe-4S dicluster domain 571 623 2.5E-9 T 13-10-2018 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 SUPERFAMILY SSF142984 380 463 6.93E-26 T 13-10-2018 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 SUPERFAMILY SSF142019 139 379 2.35E-90 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Gene3D G3DSA:3.40.50.11540 192 370 1.1E-79 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 481 492 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Pfam PF10531 SLBB domain 382 430 4.1E-7 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 SMART SM00928 468 513 7.9E-25 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0908 59b46a681c1169be4dbd02a8a2172ffe 625 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 35 109 1.7E-6 T 13-10-2018 CLOST_2333 fd0f7e80e82321cb98b89efc516a9a10 122 Pfam PF03646 FlaG protein 24 119 2.7E-26 T 13-10-2018 IPR005186 FlaG protein CLOST_2333 fd0f7e80e82321cb98b89efc516a9a10 122 SUPERFAMILY SSF160214 30 121 3.79E-26 T 13-10-2018 IPR035924 FlaG-like superfamily CLOST_2333 fd0f7e80e82321cb98b89efc516a9a10 122 Gene3D G3DSA:3.30.160.170 23 118 7.3E-29 T 13-10-2018 IPR035924 FlaG-like superfamily CLOST_0258 4696cc9810f9ecc38aa5476e06de406b 281 SUPERFAMILY SSF53067 34 136 3.77E-12 T 13-10-2018 CLOST_0258 4696cc9810f9ecc38aa5476e06de406b 281 Pfam PF11104 Type IV pilus assembly protein PilM; 146 257 2.3E-11 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM CLOST_0258 4696cc9810f9ecc38aa5476e06de406b 281 Gene3D G3DSA:3.30.420.40 146 259 3.6E-103 T 13-10-2018 CLOST_0258 4696cc9810f9ecc38aa5476e06de406b 281 TIGRFAM TIGR02529 EutJ: ethanolamine utilization protein EutJ family protein 36 274 2.4E-99 T 13-10-2018 IPR013366 Ethanolamine utilisation EutJ CLOST_0258 4696cc9810f9ecc38aa5476e06de406b 281 Gene3D G3DSA:3.30.420.40 33 273 3.6E-103 T 13-10-2018 CLOST_0258 4696cc9810f9ecc38aa5476e06de406b 281 SUPERFAMILY SSF53067 146 273 1.59E-26 T 13-10-2018 CLOST_0151 04addd2d60eef44ef1314533da67cb17 354 SUPERFAMILY SSF109604 124 293 8.85E-28 T 13-10-2018 CLOST_0151 04addd2d60eef44ef1314533da67cb17 354 Pfam PF13487 HD domain 189 248 7.3E-17 T 13-10-2018 CLOST_0151 04addd2d60eef44ef1314533da67cb17 354 Gene3D G3DSA:1.10.3210.10 1 298 3.6E-66 T 13-10-2018 CLOST_0151 04addd2d60eef44ef1314533da67cb17 354 SMART SM00471 132 267 0.0022 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_1069 50e575547da053b9c5dd8da89b23a46d 205 Gene3D G3DSA:1.10.357.10 5 197 1.6E-47 T 13-10-2018 CLOST_1069 50e575547da053b9c5dd8da89b23a46d 205 Pfam PF14278 Transcriptional regulator C-terminal region 98 176 9.7E-21 T 13-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type CLOST_1069 50e575547da053b9c5dd8da89b23a46d 205 SUPERFAMILY SSF46689 8 71 2.15E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_1069 50e575547da053b9c5dd8da89b23a46d 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 61 4.1E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_1069 50e575547da053b9c5dd8da89b23a46d 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.1E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_1069 50e575547da053b9c5dd8da89b23a46d 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.1E-6 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Gene3D G3DSA:1.10.268.10 373 461 2.9E-213 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 662 708 1.1E-13 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 559 606 1.8E-9 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 613 657 1.2E-10 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 762 807 1.5E-8 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 712 757 5.5E-12 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 510 552 9.1E-11 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Gene3D G3DSA:2.120.10.90 500 810 1.4E-120 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 808 0.0 T 13-10-2018 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 SMART SM00434 15 468 1.6E-272 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Gene3D G3DSA:3.30.1360.40 240 336 2.9E-213 T 13-10-2018 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 468 1.7E-160 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Gene3D G3DSA:3.90.199.10 36 490 2.9E-213 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 4 810 24.39 T 13-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 SUPERFAMILY SSF56719 5 492 1.96E-176 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CLOST_0006 238dd4bd06a3e2e6393b8a0b449cb16a 817 SUPERFAMILY SSF101904 503 816 3.53E-106 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CLOST_0530 3927171301376dd828b94d667d73fa72 182 Gene3D G3DSA:2.10.109.10 33 173 1.3E-31 T 13-10-2018 CLOST_0530 3927171301376dd828b94d667d73fa72 182 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 13-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CLOST_0530 3927171301376dd828b94d667d73fa72 182 ProSitePatterns PS00760 Signal peptidases I lysine active site. 92 104 - T 13-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CLOST_0530 3927171301376dd828b94d667d73fa72 182 Pfam PF10502 Signal peptidase, peptidase S26 49 169 1.0E-12 T 13-10-2018 IPR019533 Peptidase S26 CLOST_0530 3927171301376dd828b94d667d73fa72 182 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 8 176 1.5E-38 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOST_0530 3927171301376dd828b94d667d73fa72 182 SUPERFAMILY SSF51306 25 181 1.7E-44 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily CLOST_0530 3927171301376dd828b94d667d73fa72 182 ProSitePatterns PS00761 Signal peptidases I signature 3. 140 153 - T 13-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CLOST_0530 3927171301376dd828b94d667d73fa72 182 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 135 154 1.4E-18 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOST_0530 3927171301376dd828b94d667d73fa72 182 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 90 102 1.4E-18 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOST_0530 3927171301376dd828b94d667d73fa72 182 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 1.4E-18 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOST_1957 34db98e1708461d25f9bd84c8afe266b 157 Gene3D G3DSA:3.40.50.1000 9 156 6.5E-13 T 13-10-2018 IPR023214 HAD superfamily CLOST_1957 34db98e1708461d25f9bd84c8afe266b 157 Pfam PF08282 haloacid dehalogenase-like hydrolase 89 141 1.9E-5 T 13-10-2018 CLOST_1957 34db98e1708461d25f9bd84c8afe266b 157 SUPERFAMILY SSF56784 17 139 2.98E-14 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_0938 6ce2cc5af28e39ae453c13eb831006f5 559 Pfam PF01642 Methylmalonyl-CoA mutase 39 551 3.1E-225 T 13-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CLOST_0938 6ce2cc5af28e39ae453c13eb831006f5 559 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 36 556 1.3E-246 T 13-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CLOST_0938 6ce2cc5af28e39ae453c13eb831006f5 559 Gene3D G3DSA:3.20.20.240 1 559 9.7E-252 T 13-10-2018 CLOST_0938 6ce2cc5af28e39ae453c13eb831006f5 559 SUPERFAMILY SSF51703 14 553 7.26E-213 T 13-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CLOST_1540 4cf901a4739e6fb3e84e53858c609b5c 117 SUPERFAMILY SSF101386 2 117 2.62E-20 T 13-10-2018 CLOST_1540 4cf901a4739e6fb3e84e53858c609b5c 117 Pfam PF08761 dUTPase 2 92 1.5E-18 T 13-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 CLOST_1540 4cf901a4739e6fb3e84e53858c609b5c 117 Gene3D G3DSA:1.10.287.1080 13 116 4.2E-10 T 13-10-2018 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 302 85.068 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 Gene3D G3DSA:3.30.465.10 91 216 1.3E-41 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 4.6E-26 T 13-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 Gene3D G3DSA:3.90.78.10 217 302 1.4E-27 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 Gene3D G3DSA:3.30.43.10 1 86 2.8E-30 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 SUPERFAMILY SSF56176 4 194 8.72E-48 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 SUPERFAMILY SSF56194 197 301 7.59E-32 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 Pfam PF01565 FAD binding domain 36 165 4.9E-26 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CLOST_1659 8d35d3b646287fc4290972311b8a0b70 302 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 23 300 3.7E-72 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 SUPERFAMILY SSF75138 137 251 7.19E-26 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 SMART SM01131 416 542 3.6E-42 T 13-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Pfam PF00571 CBS domain 70 120 1.7E-7 T 13-10-2018 IPR000644 CBS domain CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Pfam PF00571 CBS domain 250 300 3.8E-7 T 13-10-2018 IPR000644 CBS domain CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 SUPERFAMILY SSF54631 69 299 3.61E-23 T 13-10-2018 CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Gene3D G3DSA:3.90.1640.10 3 119 2.7E-23 T 13-10-2018 CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Gene3D G3DSA:3.40.1390.20 130 244 6.4E-33 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Gene3D G3DSA:3.10.310.20 425 544 2.9E-32 T 13-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Pfam PF02833 DHHA2 domain 417 541 4.1E-13 T 13-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Gene3D G3DSA:3.90.1640.10 263 424 3.6E-45 T 13-10-2018 CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 SMART SM00116 255 303 5.3E-7 T 13-10-2018 IPR000644 CBS domain CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 SMART SM00116 77 125 0.0025 T 13-10-2018 IPR000644 CBS domain CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 SUPERFAMILY SSF64182 4 542 2.72E-67 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Pfam PF01368 DHH family 4 381 3.8E-28 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_0318 09df0358e6c352b095a0aeff06dc2199 544 Pfam PF07085 DRTGG domain 142 243 3.0E-22 T 13-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 ProSitePatterns PS00674 AAA-protein family signature. 337 355 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 SUPERFAMILY SSF140990 451 626 5.62E-42 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 SUPERFAMILY SSF52540 191 435 5.73E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 SMART SM00382 232 369 5.1E-23 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 Gene3D G3DSA:1.10.8.60 369 443 3.7E-17 T 13-10-2018 CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 236 366 1.4E-42 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 Pfam PF01434 Peptidase family M41 428 619 4.7E-37 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 Gene3D G3DSA:1.20.58.760 444 633 1.1E-45 T 13-10-2018 CLOST_0217 4c026740ac833b2a11ba160f3e285d35 645 Gene3D G3DSA:3.40.50.300 185 368 3.6E-62 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Gene3D G3DSA:3.30.110.40 577 652 7.3E-26 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Pfam PF01206 Sulfurtransferase TusA 583 651 3.8E-19 T 13-10-2018 IPR001455 TusA-like domain CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Gene3D G3DSA:3.50.50.60 115 442 1.3E-181 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0570 f024f24a0b5993af46114b657c96d466 827 SUPERFAMILY SSF64307 575 651 9.55E-20 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Gene3D G3DSA:3.50.50.60 3 341 1.3E-181 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.0E-21 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 7.0E-21 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 7.0E-21 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 7.0E-21 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 7.0E-21 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 SUPERFAMILY SSF52821 436 545 3.14E-28 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Gene3D G3DSA:3.40.250.10 452 547 1.2E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_0570 f024f24a0b5993af46114b657c96d466 827 SUPERFAMILY SSF51905 155 320 9.07E-34 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0570 f024f24a0b5993af46114b657c96d466 827 SMART SM00450 453 549 1.0E-22 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 4.0E-12 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.0E-12 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 4.0E-12 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 4.0E-12 T 13-10-2018 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 SUPERFAMILY SSF75169 677 819 2.88E-21 T 13-10-2018 IPR027396 DsrEFH-like CLOST_0570 f024f24a0b5993af46114b657c96d466 827 SUPERFAMILY SSF55424 324 448 2.23E-30 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Pfam PF13686 DsrE/DsrF/DrsH-like family 676 826 6.8E-60 T 13-10-2018 IPR032836 DsrE2-like family CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 434 1.6E-12 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 288 1.0E-57 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Gene3D G3DSA:3.40.1260.10 670 827 1.5E-67 T 13-10-2018 IPR027396 DsrEFH-like CLOST_0570 f024f24a0b5993af46114b657c96d466 827 Pfam PF00581 Rhodanese-like domain 460 544 1.3E-11 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_0570 f024f24a0b5993af46114b657c96d466 827 SUPERFAMILY SSF51905 2 199 4.32E-42 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1249 7f46c48a289183111b9c58d6f8e3e519 300 Gene3D G3DSA:1.10.150.130 5 101 1.3E-7 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal CLOST_1249 7f46c48a289183111b9c58d6f8e3e519 300 Gene3D G3DSA:1.10.443.10 115 296 7.9E-29 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CLOST_1249 7f46c48a289183111b9c58d6f8e3e519 300 SUPERFAMILY SSF56349 3 289 9.12E-37 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CLOST_1249 7f46c48a289183111b9c58d6f8e3e519 300 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 9 93 9.5E-7 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CLOST_1249 7f46c48a289183111b9c58d6f8e3e519 300 Pfam PF00589 Phage integrase family 124 278 5.7E-21 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CLOST_1600 297a6152fc8628fccb95eefa0c9b9f9b 241 Gene3D G3DSA:2.40.320.20 9 178 1.4E-7 T 13-10-2018 CLOST_1600 297a6152fc8628fccb95eefa0c9b9f9b 241 Pfam PF09359 VTC domain 10 227 1.7E-24 T 13-10-2018 IPR018966 VTC domain CLOST_1993 769a9f179f88cc24e9a0322b92b6f56a 338 SUPERFAMILY SSF47648 1 69 1.14E-11 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1993 769a9f179f88cc24e9a0322b92b6f56a 338 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 335 35.912 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CLOST_1993 769a9f179f88cc24e9a0322b92b6f56a 338 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 8 334 1.4E-118 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CLOST_1993 769a9f179f88cc24e9a0322b92b6f56a 338 Pfam PF00591 Glycosyl transferase family, a/b domain 76 325 4.6E-95 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1993 769a9f179f88cc24e9a0322b92b6f56a 338 Gene3D G3DSA:3.40.1030.10 72 338 2.6E-107 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1993 769a9f179f88cc24e9a0322b92b6f56a 338 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 68 1.9E-16 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1993 769a9f179f88cc24e9a0322b92b6f56a 338 Gene3D G3DSA:1.20.970.10 3 71 7.6E-17 T 13-10-2018 CLOST_1993 769a9f179f88cc24e9a0322b92b6f56a 338 SUPERFAMILY SSF52418 77 337 3.14E-92 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 SUPERFAMILY SSF53098 468 703 1.59E-38 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Gene3D G3DSA:1.10.10.160 113 204 9.9E-61 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Gene3D G3DSA:3.30.420.10 467 635 6.6E-36 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 SMART SM00479 467 635 1.9E-28 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Pfam PF00929 Exonuclease 469 626 2.9E-25 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Gene3D G3DSA:3.40.50.300 636 827 1.1E-26 T 13-10-2018 CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Gene3D G3DSA:3.40.50.300 297 393 4.6E-27 T 13-10-2018 CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Pfam PF13361 UvrD-like helicase C-terminal domain 295 801 1.6E-93 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Gene3D G3DSA:1.10.486.10 394 441 4.6E-27 T 13-10-2018 CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 SUPERFAMILY SSF52540 6 823 1.13E-99 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Gene3D G3DSA:3.40.50.300 10 282 9.9E-61 T 13-10-2018 CLOST_1910 eebe02f71c37835689eb22e0d8598f80 828 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 282 9.7E-47 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CLOST_2249 bbeefdb71f3faae3b25fc24c79643b19 326 Pfam PF00005 ABC transporter 33 184 1.4E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2249 bbeefdb71f3faae3b25fc24c79643b19 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 1.2E-17 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_2249 bbeefdb71f3faae3b25fc24c79643b19 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 1.2E-27 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_2249 bbeefdb71f3faae3b25fc24c79643b19 326 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2249 bbeefdb71f3faae3b25fc24c79643b19 326 SMART SM00382 41 234 1.8E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2249 bbeefdb71f3faae3b25fc24c79643b19 326 SUPERFAMILY SSF52540 5 256 1.45E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2249 bbeefdb71f3faae3b25fc24c79643b19 326 Gene3D G3DSA:3.40.50.300 3 326 9.8E-102 T 13-10-2018 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 483 85.132 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 SMART SM00116 96 144 2.6E-7 T 13-10-2018 IPR000644 CBS domain CLOST_0296 ab696ecdfb493da7c498c09818627303 487 SMART SM00116 157 205 9.8E-9 T 13-10-2018 IPR000644 CBS domain CLOST_0296 ab696ecdfb493da7c498c09818627303 487 SMART SM01240 7 470 0.0 T 13-10-2018 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 294 306 - T 13-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 SUPERFAMILY SSF54631 65 204 3.54E-29 T 13-10-2018 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 450 1.2E-192 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 470 1.9E-164 T 13-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 SUPERFAMILY SSF51412 2 474 1.13E-126 T 13-10-2018 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 PIRSF PIRSF000130 1 485 5.5E-210 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 Gene3D G3DSA:3.20.20.70 1 483 3.4E-221 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0296 ab696ecdfb493da7c498c09818627303 487 Pfam PF00571 CBS domain 96 140 1.9E-8 T 13-10-2018 IPR000644 CBS domain CLOST_0296 ab696ecdfb493da7c498c09818627303 487 Pfam PF00571 CBS domain 152 201 4.0E-7 T 13-10-2018 IPR000644 CBS domain CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 SUPERFAMILY SSF64158 76 297 2.88E-85 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 81 292 1.7E-86 T 13-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 Gene3D G3DSA:3.40.720.10 4 505 2.1E-224 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 Pfam PF01676 Metalloenzyme superfamily 3 495 2.0E-77 T 13-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 3 506 50.78 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 SUPERFAMILY SSF53649 2 505 5.12E-76 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 3 505 2.3E-226 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 Gene3D G3DSA:3.40.1450.10 76 305 2.1E-224 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_0645 ac4e900cbfb7980b278736c3928767ea 507 PIRSF PIRSF001492 1 507 1.3E-212 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CLOST_2131 4524a41b0fa95a7cd7848e7747ce2cff 347 Gene3D G3DSA:3.40.50.11030 222 347 1.6E-30 T 13-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily CLOST_2131 4524a41b0fa95a7cd7848e7747ce2cff 347 Gene3D G3DSA:3.90.870.10 7 218 2.0E-75 T 13-10-2018 CLOST_2131 4524a41b0fa95a7cd7848e7747ce2cff 347 Pfam PF01300 Telomere recombination 28 203 7.9E-53 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 CLOST_2131 4524a41b0fa95a7cd7848e7747ce2cff 347 SUPERFAMILY SSF55821 21 215 1.59E-58 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily CLOST_2131 4524a41b0fa95a7cd7848e7747ce2cff 347 Pfam PF03481 Putative GTP-binding controlling metal-binding 207 343 3.3E-24 T 13-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CLOST_2131 4524a41b0fa95a7cd7848e7747ce2cff 347 PIRSF PIRSF004930 5 347 5.7E-116 T 13-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CLOST_2131 4524a41b0fa95a7cd7848e7747ce2cff 347 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 19 214 1.6E-62 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 CLOST_1319 97635f076e87efb5d56658d26beb53c4 460 PIRSF PIRSF006603 1 452 1.0E-95 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_1319 97635f076e87efb5d56658d26beb53c4 460 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 416 1.0E-64 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_1319 97635f076e87efb5d56658d26beb53c4 460 Pfam PF01554 MatE 22 182 1.0E-28 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_1319 97635f076e87efb5d56658d26beb53c4 460 Pfam PF01554 MatE 245 401 1.9E-17 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_1457 84cbb4068244af4608e91f17174fc2a8 304 Pfam PF08239 Bacterial SH3 domain 37 85 2.5E-12 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type CLOST_1457 84cbb4068244af4608e91f17174fc2a8 304 Pfam PF00877 NlpC/P60 family 157 222 9.4E-16 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain CLOST_1457 84cbb4068244af4608e91f17174fc2a8 304 Pfam PF00877 NlpC/P60 family 259 299 8.0E-7 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain CLOST_1457 84cbb4068244af4608e91f17174fc2a8 304 Gene3D G3DSA:2.30.30.40 21 87 6.5E-16 T 13-10-2018 CLOST_1457 84cbb4068244af4608e91f17174fc2a8 304 SMART SM00287 27 88 4.8E-9 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type CLOST_1457 84cbb4068244af4608e91f17174fc2a8 304 SUPERFAMILY SSF54001 258 303 3.6E-11 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_1457 84cbb4068244af4608e91f17174fc2a8 304 SUPERFAMILY SSF54001 145 218 1.8E-22 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_2411 3705179ae0022af600469f01dc70fe97 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 302 9.7E-53 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Gene3D G3DSA:1.10.150.20 522 580 1.9E-19 T 13-10-2018 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 SUPERFAMILY SSF47781 501 582 7.63E-19 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 SMART SM00465 1 77 4.2E-19 T 13-10-2018 IPR000305 GIY-YIG endonuclease CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 1 561 2.2E-178 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Pfam PF01541 GIY-YIG catalytic domain 2 72 5.9E-9 T 13-10-2018 IPR000305 GIY-YIG endonuclease CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Pfam PF02151 UvrB/uvrC motif 188 219 3.0E-9 T 13-10-2018 IPR001943 UVR domain GO:0005515 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Gene3D G3DSA:3.40.1440.10 1 81 8.9E-29 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 SUPERFAMILY SSF82771 1 79 4.97E-20 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Gene3D G3DSA:4.10.860.10 184 223 3.5E-8 T 13-10-2018 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Hamap MF_00203 UvrABC system protein C [uvrC]. 1 579 27.265 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 368 514 3.9E-46 T 13-10-2018 IPR001162 UvrC family homology region CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 SMART SM00278 560 579 0.22 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 SMART SM00278 528 547 29.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Pfam PF14520 Helix-hairpin-helix domain 529 581 1.6E-9 T 13-10-2018 CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 Gene3D G3DSA:3.30.420.340 361 521 7.0E-54 T 13-10-2018 IPR038476 UvrC homology region 2 superfamily CLOST_0547 ff1a6a9ba7471d8ab3116e6977a220bd 587 SUPERFAMILY SSF46600 173 225 4.97E-14 T 13-10-2018 IPR036876 UVR domain superfamily CLOST_0348 886226475ff883dbd562656d67bb109b 1955 SMART SM00429 1438 1539 2.4E-6 T 13-10-2018 IPR002909 IPT domain CLOST_0348 886226475ff883dbd562656d67bb109b 1955 Gene3D G3DSA:2.60.40.10 1324 1425 1.3E-5 T 13-10-2018 IPR013783 Immunoglobulin-like fold CLOST_0348 886226475ff883dbd562656d67bb109b 1955 Gene3D G3DSA:2.60.40.10 879 979 1.0E-11 T 13-10-2018 IPR013783 Immunoglobulin-like fold CLOST_0348 886226475ff883dbd562656d67bb109b 1955 Gene3D G3DSA:2.60.40.10 1433 1543 4.4E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold CLOST_0348 886226475ff883dbd562656d67bb109b 1955 Gene3D G3DSA:2.60.40.10 1659 1779 7.7E-8 T 13-10-2018 IPR013783 Immunoglobulin-like fold CLOST_0348 886226475ff883dbd562656d67bb109b 1955 SMART SM00060 1659 1745 0.0018 T 13-10-2018 IPR003961 Fibronectin type III GO:0005515 CLOST_0348 886226475ff883dbd562656d67bb109b 1955 SUPERFAMILY SSF49265 1661 1749 1.48E-8 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 CLOST_0348 886226475ff883dbd562656d67bb109b 1955 SUPERFAMILY SSF81296 1438 1539 9.34E-9 T 13-10-2018 IPR014756 Immunoglobulin E-set CLOST_0348 886226475ff883dbd562656d67bb109b 1955 Pfam PF01833 IPT/TIG domain 1439 1538 3.3E-8 T 13-10-2018 IPR002909 IPT domain CLOST_2215 3bdb789f175db57be1803782891996eb 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.295 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CLOST_2215 3bdb789f175db57be1803782891996eb 141 SUPERFAMILY SSF46906 67 140 3.92E-27 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily CLOST_2215 3bdb789f175db57be1803782891996eb 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 2.0E-64 T 13-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2215 3bdb789f175db57be1803782891996eb 141 Gene3D G3DSA:1.10.10.250 72 140 1.1E-28 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily CLOST_2215 3bdb789f175db57be1803782891996eb 141 SUPERFAMILY SSF54747 3 72 1.57E-30 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily CLOST_2215 3bdb789f175db57be1803782891996eb 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.3E-23 T 13-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CLOST_2215 3bdb789f175db57be1803782891996eb 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-14 T 13-10-2018 CLOST_2215 3bdb789f175db57be1803782891996eb 141 Gene3D G3DSA:3.30.1550.10 2 71 1.5E-34 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily CLOST_2215 3bdb789f175db57be1803782891996eb 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 1.8E-31 T 13-10-2018 IPR020784 Ribosomal protein L11, N-terminal CLOST_2215 3bdb789f175db57be1803782891996eb 141 SMART SM00649 9 140 1.8E-86 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CLOST_2328 867807df55fa810846341d2cb0155330 65 Pfam PF14070 Putative motility protein 3 63 5.6E-21 T 13-10-2018 IPR025906 Putative motility protein CLOST_0716 eff60c579cec8d5a28cbed9ecd924307 197 Gene3D G3DSA:3.40.50.150 10 196 3.1E-44 T 13-10-2018 CLOST_0716 eff60c579cec8d5a28cbed9ecd924307 197 SUPERFAMILY SSF53335 32 188 4.76E-32 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0716 eff60c579cec8d5a28cbed9ecd924307 197 Pfam PF08241 Methyltransferase domain 48 145 1.0E-17 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CLOST_2180 db7ebff8b272a021e9495d862c54a6a2 59 SUPERFAMILY SSF55129 1 58 1.44E-19 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily CLOST_2180 db7ebff8b272a021e9495d862c54a6a2 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 7.6E-25 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2180 db7ebff8b272a021e9495d862c54a6a2 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 13-10-2018 IPR018038 Ribosomal protein L30, conserved site CLOST_2180 db7ebff8b272a021e9495d862c54a6a2 59 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 6.0E-19 T 13-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CLOST_2180 db7ebff8b272a021e9495d862c54a6a2 59 PIRSF PIRSF002211 1 59 2.6E-28 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2180 db7ebff8b272a021e9495d862c54a6a2 59 Gene3D G3DSA:3.30.1390.20 1 59 6.3E-26 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily CLOST_2180 db7ebff8b272a021e9495d862c54a6a2 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 17.862 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1689 6fbdad70f7ae2811d2d7d128f18c873b 120 Pfam PF02033 Ribosome-binding factor A 5 111 1.3E-29 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 CLOST_1689 6fbdad70f7ae2811d2d7d128f18c873b 120 ProSitePatterns PS01319 Ribosome-binding factor A signature. 77 98 - T 13-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CLOST_1689 6fbdad70f7ae2811d2d7d128f18c873b 120 Gene3D G3DSA:3.30.300.20 1 106 1.5E-29 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta CLOST_1689 6fbdad70f7ae2811d2d7d128f18c873b 120 SUPERFAMILY SSF89919 2 114 3.79E-28 T 13-10-2018 IPR023799 Ribosome-binding factor A domain superfamily CLOST_1689 6fbdad70f7ae2811d2d7d128f18c873b 120 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 7.9E-28 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 CLOST_1689 6fbdad70f7ae2811d2d7d128f18c873b 120 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 41 98 3.0E-14 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 CLOST_1689 6fbdad70f7ae2811d2d7d128f18c873b 120 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 4 111 23.694 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 Gene3D G3DSA:3.30.1360.30 274 419 2.5E-197 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 Gene3D G3DSA:2.40.50.140 1 106 1.7E-33 T 13-10-2018 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 Pfam PF01336 OB-fold nucleic acid binding domain 19 102 3.4E-14 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 PRINTS PR01042 Aspartyl-tRNA synthetase signature 209 222 1.1E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 1.1E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 PRINTS PR01042 Aspartyl-tRNA synthetase signature 192 204 1.1E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 1.1E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 581 8.8E-249 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 Pfam PF00152 tRNA synthetases class II (D, K and N) 120 558 5.2E-112 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 584 33.899 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 SUPERFAMILY SSF50249 2 109 3.81E-33 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 Pfam PF02938 GAD domain 313 405 1.5E-24 T 13-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 SUPERFAMILY SSF55681 108 585 5.36E-109 T 13-10-2018 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 Gene3D G3DSA:3.30.930.10 118 581 2.5E-197 T 13-10-2018 CLOST_1300 1df9fa45d5d0f79238cf9f7323571eee 586 SUPERFAMILY SSF55261 291 418 1.23E-36 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CLOST_1203 cb3178e4af60f818805b58031474e0a0 275 SUPERFAMILY SSF161098 9 261 6.92E-55 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1203 cb3178e4af60f818805b58031474e0a0 275 Gene3D G3DSA:1.10.3720.10 20 269 2.8E-50 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1203 cb3178e4af60f818805b58031474e0a0 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 267 2.4E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0462 b38d40c300afcaa3523f59abb51654c3 215 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 3.3E-104 T 13-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CLOST_0462 b38d40c300afcaa3523f59abb51654c3 215 SUPERFAMILY SSF51569 1 213 1.04E-81 T 13-10-2018 CLOST_0462 b38d40c300afcaa3523f59abb51654c3 215 Gene3D G3DSA:3.20.20.70 1 214 9.3E-93 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0462 b38d40c300afcaa3523f59abb51654c3 215 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 207 8.1E-60 T 13-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 CLOST_0462 b38d40c300afcaa3523f59abb51654c3 215 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 13-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 CLOST_0462 b38d40c300afcaa3523f59abb51654c3 215 Hamap MF_00494 Probable transaldolase [tal]. 1 215 48.775 T 13-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CLOST_0462 b38d40c300afcaa3523f59abb51654c3 215 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 13-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 PIRSF PIRSF000538 1 489 1.6E-162 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 SUPERFAMILY SSF53067 246 485 1.66E-63 T 13-10-2018 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 Gene3D G3DSA:3.30.420.40 2 244 3.5E-86 T 13-10-2018 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 SUPERFAMILY SSF53067 2 246 1.94E-79 T 13-10-2018 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 TIGRFAM TIGR01312 XylB: xylulokinase 4 479 4.4E-176 T 13-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 350 370 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 Gene3D G3DSA:3.30.420.40 246 487 2.1E-79 T 13-10-2018 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 129 141 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 254 436 2.7E-41 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CLOST_0775 02f48006d6f50f683e136fabc0a0376f 489 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 2 244 5.2E-77 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 Gene3D G3DSA:3.40.50.12740 2 160 3.7E-36 T 13-10-2018 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 Gene3D G3DSA:1.10.10.60 410 459 7.6E-19 T 13-10-2018 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 SMART SM00448 2 116 6.8E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 SUPERFAMILY SSF46689 413 461 4.08E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 SUPERFAMILY SSF52172 1 125 1.71E-34 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 464 506 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 SUPERFAMILY SSF46689 463 511 1.7E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 479 494 1.8E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 494 510 1.8E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 Pfam PF00072 Response regulator receiver domain 4 116 6.7E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 Gene3D G3DSA:1.10.10.60 460 513 3.9E-18 T 13-10-2018 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 Pfam PF12833 Helix-turn-helix domain 433 511 1.9E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOST_0540 23732d689c652a3412bd4374bf1e58a0 515 SMART SM00342 427 510 2.2E-28 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOST_0576 9b0a429448c7c5bc1037e163c4a2e92b 458 Pfam PF01554 MatE 22 182 3.0E-34 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0576 9b0a429448c7c5bc1037e163c4a2e92b 458 Pfam PF01554 MatE 249 411 5.5E-16 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0576 9b0a429448c7c5bc1037e163c4a2e92b 458 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 417 1.3E-65 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0576 9b0a429448c7c5bc1037e163c4a2e92b 458 PIRSF PIRSF006603 1 456 2.5E-73 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0647 642f6518329004b651814de9d99bb036 75 Pfam PF03840 Preprotein translocase SecG subunit 4 73 1.0E-19 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOST_0647 642f6518329004b651814de9d99bb036 75 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 74 5.2E-19 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOST_0647 642f6518329004b651814de9d99bb036 75 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.5E-11 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOST_0647 642f6518329004b651814de9d99bb036 75 PRINTS PR01651 Protein-export SecG membrane protein signature 55 75 1.5E-11 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOST_0647 642f6518329004b651814de9d99bb036 75 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.5E-11 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 56 2.7E-11 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 303 353 2.2E-9 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 63 292 8.9E-38 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 450 461 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Gene3D G3DSA:3.30.1490.20 11 243 1.1E-106 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 871 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Gene3D G3DSA:1.20.80.30 111 198 1.1E-106 T 13-10-2018 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Gene3D G3DSA:3.20.20.60 532 873 1.7E-150 T 13-10-2018 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 PIRSF PIRSF000853 2 879 0.0 T 13-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Gene3D G3DSA:3.50.30.10 383 507 1.0E-78 T 13-10-2018 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 SUPERFAMILY SSF51621 512 869 3.71E-130 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 SUPERFAMILY SSF52009 380 508 9.42E-38 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Pfam PF00391 PEP-utilising enzyme, mobile domain 422 503 2.2E-27 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Gene3D G3DSA:1.10.189.10 345 529 1.0E-78 T 13-10-2018 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Gene3D G3DSA:3.30.470.20 244 341 2.2E-42 T 13-10-2018 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 SUPERFAMILY SSF56059 2 379 7.65E-147 T 13-10-2018 CLOST_1767 29bee56dd7d3227ff025bd9c0db4f735 881 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 517 869 8.4E-92 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 166 1.3E-26 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 PIRSF PIRSF006728 1 413 2.5E-152 T 13-10-2018 IPR008135 Competence-induced protein CinA CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 Pfam PF00994 Probable molybdopterin binding domain 4 170 5.7E-33 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 414 161.481 T 13-10-2018 IPR008135 Competence-induced protein CinA CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 SMART SM00852 4 171 3.4E-39 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 Pfam PF02464 Competence-damaged protein 255 408 5.8E-56 T 13-10-2018 IPR008136 CinA, C-terminal CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 409 9.6E-118 T 13-10-2018 IPR008135 Competence-induced protein CinA CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 Gene3D G3DSA:3.90.950.20 245 409 8.0E-57 T 13-10-2018 IPR036653 CinA-like, C-terminal CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 SUPERFAMILY SSF53218 1 203 9.82E-39 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 Gene3D G3DSA:3.40.980.10 1 171 2.1E-52 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 SUPERFAMILY SSF142433 249 408 6.15E-54 T 13-10-2018 IPR036653 CinA-like, C-terminal CLOST_1814 460df61749e06a4e8c5530a97adfea64 414 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 262 408 4.7E-48 T 13-10-2018 IPR008136 CinA, C-terminal CLOST_1436 3dbbd0c5ff1e372071aca0a8af9bf3b9 74 SUPERFAMILY SSF64307 5 73 6.93E-22 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_1436 3dbbd0c5ff1e372071aca0a8af9bf3b9 74 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 13-10-2018 IPR001455 TusA-like domain CLOST_1436 3dbbd0c5ff1e372071aca0a8af9bf3b9 74 Gene3D G3DSA:3.30.110.40 1 73 7.1E-23 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_1436 3dbbd0c5ff1e372071aca0a8af9bf3b9 74 Pfam PF01206 Sulfurtransferase TusA 5 73 5.0E-24 T 13-10-2018 IPR001455 TusA-like domain CLOST_0192 726baed3f012ae08066273188548dc7a 186 Pfam PF05137 Fimbrial assembly protein (PilN) 110 177 1.2E-10 T 13-10-2018 IPR007813 Fimbrial assembly PilN CLOST_1946 f050e8054585318540a2cdac124b22d9 348 SUPERFAMILY SSF52218 163 318 8.18E-17 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_1946 f050e8054585318540a2cdac124b22d9 348 Pfam PF03358 NADPH-dependent FMN reductase 162 302 1.7E-15 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CLOST_1946 f050e8054585318540a2cdac124b22d9 348 Gene3D G3DSA:3.40.50.360 162 348 2.9E-25 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 TIGRFAM TIGR01069 mutS2: MutS2 family protein 6 793 1.0E-219 T 13-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 SUPERFAMILY SSF52540 294 514 5.05E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 SMART SM00534 329 514 8.1E-67 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 Gene3D G3DSA:3.40.50.300 296 636 4.1E-79 T 13-10-2018 CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 7 792 20.779 T 13-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 PIRSF PIRSF005814 4 793 7.5E-255 T 13-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 SUPERFAMILY SSF160443 716 792 3.4E-8 T 13-10-2018 IPR036063 Smr domain superfamily CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 SUPERFAMILY SSF48334 23 288 1.19E-25 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 SMART SM00463 715 793 8.1E-15 T 13-10-2018 IPR002625 Smr domain CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 Pfam PF01713 Smr domain 718 793 3.0E-17 T 13-10-2018 IPR002625 Smr domain CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 Gene3D G3DSA:3.30.1370.110 705 793 1.3E-22 T 13-10-2018 CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 Pfam PF00488 MutS domain V 332 513 1.8E-34 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_1146 da408dc25dacabfe0dbe4718d501de80 793 SMART SM00533 14 316 1.9E-16 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 337 3.0E-69 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 2 18 1.5E-18 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 108 122 1.5E-18 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 154 167 1.5E-18 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 70 82 - T 13-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 339 3.5E-78 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 Gene3D G3DSA:3.90.120.10 150 327 2.0E-105 T 13-10-2018 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 SUPERFAMILY SSF53335 2 339 6.88E-96 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 320 338 - T 13-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CLOST_0308 43d6e40df373a0b893d065c9e5339a0e 344 Gene3D G3DSA:3.40.50.150 4 332 2.0E-105 T 13-10-2018 CLOST_0435 0bf7f8f0e8761b0efaeaa9226f5e6931 349 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 317 5.9E-96 T 13-10-2018 IPR016040 NAD(P)-binding domain CLOST_0435 0bf7f8f0e8761b0efaeaa9226f5e6931 349 SUPERFAMILY SSF51735 3 346 4.51E-98 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0435 0bf7f8f0e8761b0efaeaa9226f5e6931 349 Gene3D G3DSA:3.90.25.10 205 326 3.0E-135 T 13-10-2018 CLOST_0435 0bf7f8f0e8761b0efaeaa9226f5e6931 349 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 333 7.1E-154 T 13-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CLOST_0435 0bf7f8f0e8761b0efaeaa9226f5e6931 349 Gene3D G3DSA:3.40.50.720 3 318 3.0E-135 T 13-10-2018 CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 TIGRFAM TIGR02911 sulfite_red_B: sulfite reductase, subunit B 3 262 7.2E-104 T 13-10-2018 IPR014260 Sulphite reductase, subunit B CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 Gene3D G3DSA:2.40.30.10 5 92 1.8E-12 T 13-10-2018 CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 225 256 1.1E-8 T 13-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 PRINTS PR00410 Phenol hydroxylase reductase family signature 104 123 6.1E-7 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 PRINTS PR00410 Phenol hydroxylase reductase family signature 32 44 6.1E-7 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 PRINTS PR00410 Phenol hydroxylase reductase family signature 193 201 6.1E-7 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 SUPERFAMILY SSF63380 4 93 3.05E-19 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 PIRSF PIRSF006816 3 261 1.6E-69 T 13-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 Gene3D G3DSA:3.40.50.80 93 226 1.2E-21 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 SUPERFAMILY SSF52343 98 241 1.7E-30 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CLOST_2028 969d7b001d98338477c0aa6c578cbeef 262 Pfam PF00175 Oxidoreductase NAD-binding domain 105 206 2.5E-15 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 SUPERFAMILY SSF47384 68 147 9.81E-15 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 SMART SM00387 194 306 1.5E-38 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 195 304 6.6E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 SMART SM00388 82 149 2.8E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 PRINTS PR00344 Bacterial sensor protein C-terminal signature 266 284 5.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 303 5.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 PRINTS PR00344 Bacterial sensor protein C-terminal signature 231 245 5.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 PRINTS PR00344 Bacterial sensor protein C-terminal signature 249 259 5.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 SUPERFAMILY SSF55874 139 305 1.19E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 Pfam PF00512 His Kinase A (phospho-acceptor) domain 83 143 7.5E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 Gene3D G3DSA:1.10.287.130 36 143 1.3E-15 T 13-10-2018 CLOST_1355 420a1e717d17d5d74088036e1f6b72f9 316 Gene3D G3DSA:3.30.565.10 158 309 1.2E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 SUPERFAMILY SSF50156 87 171 1.22E-14 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 Gene3D G3DSA:2.30.42.10 90 176 5.3E-86 T 13-10-2018 CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 SMART SM00245 162 348 1.2E-60 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 Gene3D G3DSA:3.30.750.44 23 323 5.3E-86 T 13-10-2018 CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 Pfam PF03572 Peptidase family S41 187 346 2.8E-49 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 SUPERFAMILY SSF52096 23 353 3.15E-71 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 SMART SM00228 90 162 4.4E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 Gene3D G3DSA:3.90.226.10 177 344 5.3E-86 T 13-10-2018 CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 44 352 3.0E-89 T 13-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CLOST_0351 79a8d57fb54ecd0ae838ab54a2394f03 372 Pfam PF13180 PDZ domain 90 169 3.2E-14 T 13-10-2018 IPR001478 PDZ domain GO:0005515 CLOST_1487 574f10f766c2612acabdb40210a09c2e 139 SMART SM00732 2 104 3.5E-31 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CLOST_1487 574f10f766c2612acabdb40210a09c2e 139 SUPERFAMILY SSF53098 2 137 6.07E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1487 574f10f766c2612acabdb40210a09c2e 139 Gene3D G3DSA:3.30.420.140 1 139 7.4E-46 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 CLOST_1487 574f10f766c2612acabdb40210a09c2e 139 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 5 136 1.4E-35 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CLOST_1487 574f10f766c2612acabdb40210a09c2e 139 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 2 139 24.664 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CLOST_1487 574f10f766c2612acabdb40210a09c2e 139 Pfam PF03652 Holliday junction resolvase 3 137 5.3E-43 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CLOST_0660 0648d2a66c304ae806613476152d97e8 690 Pfam PF00990 Diguanylate cyclase, GGDEF domain 266 415 3.5E-24 T 13-10-2018 IPR000160 GGDEF domain CLOST_0660 0648d2a66c304ae806613476152d97e8 690 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 266 415 4.4E-15 T 13-10-2018 IPR000160 GGDEF domain CLOST_0660 0648d2a66c304ae806613476152d97e8 690 Gene3D G3DSA:3.30.70.270 262 435 1.5E-30 T 13-10-2018 CLOST_0660 0648d2a66c304ae806613476152d97e8 690 SMART SM00267 253 423 8.6E-8 T 13-10-2018 IPR000160 GGDEF domain CLOST_0660 0648d2a66c304ae806613476152d97e8 690 Pfam PF00563 EAL domain 439 677 1.6E-63 T 13-10-2018 IPR001633 EAL domain CLOST_0660 0648d2a66c304ae806613476152d97e8 690 Gene3D G3DSA:3.20.20.450 436 690 1.5E-84 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0660 0648d2a66c304ae806613476152d97e8 690 SUPERFAMILY SSF103190 134 225 3.22E-6 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0660 0648d2a66c304ae806613476152d97e8 690 SUPERFAMILY SSF55073 269 424 4.94E-22 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0660 0648d2a66c304ae806613476152d97e8 690 SUPERFAMILY SSF141868 451 687 6.8E-78 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0660 0648d2a66c304ae806613476152d97e8 690 SMART SM00052 433 682 4.4E-95 T 13-10-2018 IPR001633 EAL domain CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 SUPERFAMILY SSF53335 1 314 4.82E-78 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 Gene3D G3DSA:3.40.50.150 3 308 1.3E-83 T 13-10-2018 CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 Gene3D G3DSA:3.90.120.10 155 301 1.3E-83 T 13-10-2018 CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 1 308 1.2E-79 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 204 2.3E-58 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 Pfam PF00145 C-5 cytosine-specific DNA methylase 233 310 9.3E-13 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 292 310 - T 13-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 114 128 5.6E-9 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 160 173 5.6E-9 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0310 5d22991cb43134d69ddd38d679c76b15 326 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 72 84 - T 13-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 CLOST_0693 4c0592f94354c2da77a3414de161c851 360 Gene3D G3DSA:1.20.58.340 170 281 2.9E-26 T 13-10-2018 CLOST_0693 4c0592f94354c2da77a3414de161c851 360 Gene3D G3DSA:1.20.58.340 283 360 2.5E-24 T 13-10-2018 CLOST_0693 4c0592f94354c2da77a3414de161c851 360 SUPERFAMILY SSF144083 295 357 4.58E-18 T 13-10-2018 CLOST_0693 4c0592f94354c2da77a3414de161c851 360 Gene3D G3DSA:3.30.460.20 8 169 1.8E-35 T 13-10-2018 CLOST_0693 4c0592f94354c2da77a3414de161c851 360 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 60 360 2.1E-71 T 13-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CLOST_0693 4c0592f94354c2da77a3414de161c851 360 SUPERFAMILY SSF143865 17 293 3.92E-59 T 13-10-2018 CLOST_0693 4c0592f94354c2da77a3414de161c851 360 Pfam PF01544 CorA-like Mg2+ transporter protein 69 355 1.8E-56 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CLOST_2548 699cbea4d67aefb78fcc7060bb8ddb82 263 Pfam PF00005 ABC transporter 24 173 7.3E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2548 699cbea4d67aefb78fcc7060bb8ddb82 263 SUPERFAMILY SSF52540 5 226 1.95E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2548 699cbea4d67aefb78fcc7060bb8ddb82 263 Gene3D G3DSA:3.40.50.300 3 252 9.2E-68 T 13-10-2018 CLOST_2548 699cbea4d67aefb78fcc7060bb8ddb82 263 SMART SM00382 33 222 1.4E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2548 699cbea4d67aefb78fcc7060bb8ddb82 263 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 350 2.1E-43 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 392 552 3.8E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 574 697 7.1E-34 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 Gene3D G3DSA:2.70.150.10 20 226 1.5E-281 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 Pfam PF00702 haloacid dehalogenase-like hydrolase 319 621 1.9E-25 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 Pfam PF00690 Cation transporter/ATPase, N-terminus 5 70 3.1E-16 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 Pfam PF00689 Cation transporting ATPase, C-terminus 692 861 9.5E-43 T 13-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 SUPERFAMILY SSF81665 2 862 1.83E-116 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 SMART SM00831 2 75 1.0E-24 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 SUPERFAMILY SSF56784 321 712 1.9E-57 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 579 595 7.0E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 465 483 7.0E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 639 664 7.0E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 607 623 7.0E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 Pfam PF00122 E1-E2 ATPase 110 302 2.5E-55 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 325 331 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 323 337 1.7E-40 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 631 643 1.7E-40 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 1.7E-40 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 537 1.7E-40 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 607 626 1.7E-40 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 505 516 1.7E-40 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 Gene3D G3DSA:1.20.1110.10 53 859 1.5E-281 T 13-10-2018 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 SUPERFAMILY SSF81653 113 223 9.42E-30 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 Gene3D G3DSA:3.40.50.1000 320 652 1.5E-281 T 13-10-2018 IPR023214 HAD superfamily CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 Gene3D G3DSA:3.40.1110.10 333 512 1.5E-281 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CLOST_1604 a3a9a5fce8daeb71a403e7f94a69a0eb 882 SUPERFAMILY SSF81660 332 513 9.48E-47 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CLOST_0704 4f1489acf72ca3a33ec06fdac8471fc7 279 Pfam PF02678 Pirin 22 119 7.7E-32 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CLOST_0704 4f1489acf72ca3a33ec06fdac8471fc7 279 Gene3D G3DSA:2.60.120.10 16 268 1.6E-83 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0704 4f1489acf72ca3a33ec06fdac8471fc7 279 Gene3D G3DSA:2.60.120.10 141 242 1.6E-83 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0704 4f1489acf72ca3a33ec06fdac8471fc7 279 Pfam PF05726 Pirin C-terminal cupin domain 172 272 1.5E-20 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CLOST_0704 4f1489acf72ca3a33ec06fdac8471fc7 279 SUPERFAMILY SSF51182 1 273 6.63E-76 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0704 4f1489acf72ca3a33ec06fdac8471fc7 279 PIRSF PIRSF006232 1 278 1.5E-80 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CLOST_1680 62b3a3640a35ee9d4c3ae60be025d5b5 172 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 48 70 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CLOST_1680 62b3a3640a35ee9d4c3ae60be025d5b5 172 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 169 4.8E-50 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CLOST_1680 62b3a3640a35ee9d4c3ae60be025d5b5 172 PIRSF PIRSF000847 1 172 2.1E-49 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CLOST_1680 62b3a3640a35ee9d4c3ae60be025d5b5 172 Gene3D G3DSA:1.20.120.1760 3 169 5.7E-14 T 13-10-2018 CLOST_1680 62b3a3640a35ee9d4c3ae60be025d5b5 172 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 70 1.7E-16 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CLOST_2349 0bbf5c373a2eda5cf1813b3fa926879c 518 Pfam PF00460 Flagella basal body rod protein 8 38 6.3E-7 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CLOST_2349 0bbf5c373a2eda5cf1813b3fa926879c 518 PRINTS PR01005 Flagellar hook-associated protein signature 129 149 2.4E-9 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CLOST_2349 0bbf5c373a2eda5cf1813b3fa926879c 518 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 2.4E-9 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CLOST_2349 0bbf5c373a2eda5cf1813b3fa926879c 518 PRINTS PR01005 Flagellar hook-associated protein signature 162 186 2.4E-9 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CLOST_2349 0bbf5c373a2eda5cf1813b3fa926879c 518 SUPERFAMILY SSF64518 132 511 3.92E-15 T 13-10-2018 CLOST_2349 0bbf5c373a2eda5cf1813b3fa926879c 518 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 511 1.1E-98 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CLOST_2349 0bbf5c373a2eda5cf1813b3fa926879c 518 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 460 511 1.4E-13 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CLOST_0444 b037275f6c861b1c1e68572b221e639c 310 Pfam PF00535 Glycosyl transferase family 2 5 137 4.2E-24 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CLOST_0444 b037275f6c861b1c1e68572b221e639c 310 SUPERFAMILY SSF53448 2 240 1.88E-24 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0444 b037275f6c861b1c1e68572b221e639c 310 Gene3D G3DSA:3.90.550.10 1 199 2.4E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_1377 06492bf456b713d9d74a129eb0e2d671 613 Pfam PF04055 Radical SAM superfamily 263 424 1.8E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1377 06492bf456b713d9d74a129eb0e2d671 613 SUPERFAMILY SSF102114 220 593 5.23E-49 T 13-10-2018 CLOST_1377 06492bf456b713d9d74a129eb0e2d671 613 Gene3D G3DSA:3.80.30.20 257 443 1.1E-19 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1377 06492bf456b713d9d74a129eb0e2d671 613 SMART SM00729 258 486 3.8E-24 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1377 06492bf456b713d9d74a129eb0e2d671 613 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 8 613 1.1E-282 T 13-10-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM CLOST_0343 41143a761139338f1617b03dbd6f522c 80 Gene3D G3DSA:3.10.290.10 1 80 3.1E-24 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_0343 41143a761139338f1617b03dbd6f522c 80 PIRSF PIRSF038881 1 80 7.3E-33 T 13-10-2018 IPR025490 RNA-binding protein, HP1423 type CLOST_0343 41143a761139338f1617b03dbd6f522c 80 SUPERFAMILY SSF55174 1 76 1.26E-19 T 13-10-2018 CLOST_0343 41143a761139338f1617b03dbd6f522c 80 SMART SM00363 1 64 1.8E-7 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_0343 41143a761139338f1617b03dbd6f522c 80 Pfam PF01479 S4 domain 1 46 2.2E-7 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_0563 8efb8d427a9adfff14c9f8dadd310281 184 Pfam PF12389 Camelysin metallo-endopeptidase 1 72 2.2E-5 T 13-10-2018 IPR022121 Peptidase M73, camelysin CLOST_0563 8efb8d427a9adfff14c9f8dadd310281 184 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 10 42 8.1E-9 T 13-10-2018 IPR023833 Signal peptide, camelysin CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SUPERFAMILY SSF55073 313 454 3.22E-34 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SUPERFAMILY SSF55785 176 269 6.47E-9 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SMART SM00091 27 93 0.0012 T 13-10-2018 IPR000014 PAS domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SMART SM00091 183 257 3.3 T 13-10-2018 IPR000014 PAS domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SMART SM00086 98 139 4.3E-4 T 13-10-2018 IPR001610 PAC motif CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 Gene3D G3DSA:3.30.450.20 174 297 1.4E-15 T 13-10-2018 CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SUPERFAMILY SSF55785 32 139 3.32E-17 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 Gene3D G3DSA:1.10.3210.10 458 639 3.3E-64 T 13-10-2018 CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SMART SM00471 474 609 6.4E-11 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 Gene3D G3DSA:3.30.70.270 299 457 5.3E-42 T 13-10-2018 CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 Pfam PF01966 HD domain 481 600 5.9E-17 T 13-10-2018 IPR006674 HD domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SMART SM00267 297 466 5.8E-35 T 13-10-2018 IPR000160 GGDEF domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 307 458 2.2E-35 T 13-10-2018 IPR000160 GGDEF domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 184 264 7.4E-6 T 13-10-2018 IPR000014 PAS domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 38 145 2.1E-16 T 13-10-2018 IPR000014 PAS domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 SUPERFAMILY SSF109604 478 635 5.8E-35 T 13-10-2018 CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 Pfam PF13426 PAS domain 40 137 1.4E-8 T 13-10-2018 IPR000014 PAS domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 Pfam PF00990 Diguanylate cyclase, GGDEF domain 309 455 1.9E-34 T 13-10-2018 IPR000160 GGDEF domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 Pfam PF13188 PAS domain 183 243 1.9E-8 T 13-10-2018 IPR000014 PAS domain CLOST_0670 0774e994c73f3c8b28b8c7f0b98f54a6 642 Gene3D G3DSA:3.30.450.20 30 151 1.1E-17 T 13-10-2018 CLOST_0787 478f63ca0c5f9d5144879deddecd1300 219 SUPERFAMILY SSF52540 20 216 3.06E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0787 478f63ca0c5f9d5144879deddecd1300 219 Gene3D G3DSA:3.40.50.300 1 218 7.6E-57 T 13-10-2018 CLOST_0787 478f63ca0c5f9d5144879deddecd1300 219 SMART SM00382 32 214 1.7E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0787 478f63ca0c5f9d5144879deddecd1300 219 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0787 478f63ca0c5f9d5144879deddecd1300 219 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 36 49 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CLOST_0787 478f63ca0c5f9d5144879deddecd1300 219 Pfam PF00005 ABC transporter 24 167 2.4E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2565 21af614feb4cd2eb644e12478c4983e4 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 4.2E-46 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2565 21af614feb4cd2eb644e12478c4983e4 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 1.3E-30 T 13-10-2018 IPR020069 Ribosomal protein L9, C-terminal CLOST_2565 21af614feb4cd2eb644e12478c4983e4 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 5.2E-22 T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2565 21af614feb4cd2eb644e12478c4983e4 149 Gene3D G3DSA:3.10.430.100 60 148 3.2E-33 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily CLOST_2565 21af614feb4cd2eb644e12478c4983e4 149 SUPERFAMILY SSF55653 57 147 2.75E-28 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily CLOST_2565 21af614feb4cd2eb644e12478c4983e4 149 Gene3D G3DSA:3.40.5.10 1 52 3.2E-24 T 13-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2565 21af614feb4cd2eb644e12478c4983e4 149 SUPERFAMILY SSF55658 1 55 1.06E-15 T 13-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CLOST_2565 21af614feb4cd2eb644e12478c4983e4 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.022 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_0747 8dd64c0709eebf7daa1289bc1ee88ce1 1168 Gene3D G3DSA:3.40.50.300 797 1165 9.9E-21 T 13-10-2018 CLOST_0747 8dd64c0709eebf7daa1289bc1ee88ce1 1168 Gene3D G3DSA:3.40.50.300 1 265 1.2E-35 T 13-10-2018 CLOST_0747 8dd64c0709eebf7daa1289bc1ee88ce1 1168 SUPERFAMILY SSF52540 24 1143 3.59E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0747 8dd64c0709eebf7daa1289bc1ee88ce1 1168 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1056 1123 2.1E-13 T 13-10-2018 CLOST_0336 b2050abe8e7aadd0de96bdd07e046058 352 SUPERFAMILY SSF56042 174 347 1.94E-53 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_0336 b2050abe8e7aadd0de96bdd07e046058 352 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 8 350 44.412 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_0336 b2050abe8e7aadd0de96bdd07e046058 352 Pfam PF00586 AIR synthase related protein, N-terminal domain 64 166 2.4E-16 T 13-10-2018 IPR016188 PurM-like, N-terminal domain CLOST_0336 b2050abe8e7aadd0de96bdd07e046058 352 Gene3D G3DSA:3.30.1330.10 7 173 2.2E-64 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_0336 b2050abe8e7aadd0de96bdd07e046058 352 Gene3D G3DSA:3.90.650.10 174 351 3.0E-61 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_0336 b2050abe8e7aadd0de96bdd07e046058 352 Pfam PF02769 AIR synthase related protein, C-terminal domain 179 346 2.6E-31 T 13-10-2018 IPR010918 PurM-like, C-terminal domain CLOST_0336 b2050abe8e7aadd0de96bdd07e046058 352 SUPERFAMILY SSF55326 7 172 2.79E-46 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_0336 b2050abe8e7aadd0de96bdd07e046058 352 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 341 1.9E-131 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CLOST_1721 58d2f836f9adacdbee5abff9ac498ec9 262 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 15 252 8.4E-60 T 13-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CLOST_1721 58d2f836f9adacdbee5abff9ac498ec9 262 Pfam PF01311 Bacterial export proteins, family 1 14 247 7.0E-65 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CLOST_1721 58d2f836f9adacdbee5abff9ac498ec9 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.2E-20 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CLOST_1721 58d2f836f9adacdbee5abff9ac498ec9 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.2E-20 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CLOST_1721 58d2f836f9adacdbee5abff9ac498ec9 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 204 223 1.2E-20 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CLOST_1721 58d2f836f9adacdbee5abff9ac498ec9 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 182 204 1.2E-20 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CLOST_2145 b5ca9017dfd1dc2a9777b8d1e3030834 291 Pfam PF04468 PSP1 C-terminal conserved region 61 146 4.4E-32 T 13-10-2018 IPR007557 PSP1, C-terminal CLOST_0970 d64be2ef340eada2ae7295352099a68e 810 PIRSF PIRSF000460 1 808 2.4E-218 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CLOST_0970 d64be2ef340eada2ae7295352099a68e 810 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 5 803 0.0 T 13-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CLOST_0970 d64be2ef340eada2ae7295352099a68e 810 SUPERFAMILY SSF53756 4 804 9.42E-298 T 13-10-2018 CLOST_0970 d64be2ef340eada2ae7295352099a68e 810 Gene3D G3DSA:3.40.50.2000 20 803 0.0 T 13-10-2018 CLOST_0970 d64be2ef340eada2ae7295352099a68e 810 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 647 659 - T 13-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CLOST_0970 d64be2ef340eada2ae7295352099a68e 810 Gene3D G3DSA:3.40.50.2000 469 797 0.0 T 13-10-2018 CLOST_0970 d64be2ef340eada2ae7295352099a68e 810 Pfam PF00343 Carbohydrate phosphorylase 94 803 0.0 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 Gene3D G3DSA:3.40.50.720 1 164 2.7E-54 T 13-10-2018 CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 SUPERFAMILY SSF51735 3 159 5.75E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 27.95 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 98 1.3E-23 T 13-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 SUPERFAMILY SSF48179 161 266 1.11E-38 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 6.0E-89 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 Gene3D G3DSA:1.10.3730.10 165 266 3.2E-41 T 13-10-2018 CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 1.0E-41 T 13-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CLOST_1972 48fee466a331c090e5e61283f8412ceb 266 PIRSF PIRSF000193 2 266 2.6E-90 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CLOST_0650 b54464a1cd3594bf4948c8b8330e7c50 288 Gene3D G3DSA:3.40.50.720 7 180 1.5E-40 T 13-10-2018 CLOST_0650 b54464a1cd3594bf4948c8b8330e7c50 288 SUPERFAMILY SSF48179 184 286 3.74E-23 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CLOST_0650 b54464a1cd3594bf4948c8b8330e7c50 288 Gene3D G3DSA:1.10.3660.10 183 287 1.8E-24 T 13-10-2018 CLOST_0650 b54464a1cd3594bf4948c8b8330e7c50 288 SUPERFAMILY SSF51735 14 177 5.15E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0650 b54464a1cd3594bf4948c8b8330e7c50 288 Pfam PF02153 Prephenate dehydrogenase 26 279 6.6E-52 T 13-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 8 481 6.0E-162 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PIRSF PIRSF016599 1 482 7.0E-163 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 Pfam PF07687 Peptidase dimerisation domain 210 288 3.6E-8 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 SUPERFAMILY SSF53187 11 480 6.0E-51 T 13-10-2018 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 Gene3D G3DSA:3.40.630.10 369 482 1.3E-19 T 13-10-2018 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PRINTS PR00934 X-His dipeptidase (M25) signature 360 378 8.3E-47 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PRINTS PR00934 X-His dipeptidase (M25) signature 158 176 8.3E-47 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PRINTS PR00934 X-His dipeptidase (M25) signature 134 151 8.3E-47 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PRINTS PR00934 X-His dipeptidase (M25) signature 204 221 8.3E-47 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PRINTS PR00934 X-His dipeptidase (M25) signature 449 471 8.3E-47 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PRINTS PR00934 X-His dipeptidase (M25) signature 249 268 8.3E-47 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PRINTS PR00934 X-His dipeptidase (M25) signature 79 98 8.3E-47 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 PRINTS PR00934 X-His dipeptidase (M25) signature 100 118 8.3E-47 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 Pfam PF01546 Peptidase family M20/M25/M40 71 479 1.1E-20 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 CLOST_1442 ae518d2c79fde8b8a01e3735f252b39a 482 Gene3D G3DSA:3.40.630.10 4 238 2.9E-51 T 13-10-2018 CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 Gene3D G3DSA:3.40.190.10 143 240 1.6E-67 T 13-10-2018 CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 60 277 3.1E-38 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 SUPERFAMILY SSF55073 342 482 5.02E-29 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 Pfam PF13487 HD domain 557 618 3.4E-19 T 13-10-2018 CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 Gene3D G3DSA:3.40.190.10 48 276 1.6E-67 T 13-10-2018 CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 Pfam PF00990 Diguanylate cyclase, GGDEF domain 338 482 5.3E-31 T 13-10-2018 IPR000160 GGDEF domain CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 Gene3D G3DSA:3.30.70.270 323 483 4.5E-35 T 13-10-2018 CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 SMART SM00267 326 489 1.8E-32 T 13-10-2018 IPR000160 GGDEF domain CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 SUPERFAMILY SSF53850 60 278 4.41E-47 T 13-10-2018 CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 SUPERFAMILY SSF109604 498 668 8.48E-30 T 13-10-2018 CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 Gene3D G3DSA:1.10.3210.10 484 669 4.4E-58 T 13-10-2018 CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 336 484 1.0E-33 T 13-10-2018 IPR000160 GGDEF domain CLOST_0405 b785d0c7f6d565b62bc3cc933ecbf70f 669 SMART SM00062 59 278 1.1E-25 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_0770 3ca4fe1952247477c8420a244ae843e4 332 Pfam PF13377 Periplasmic binding protein-like domain 164 323 1.3E-28 T 13-10-2018 CLOST_0770 3ca4fe1952247477c8420a244ae843e4 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 5.8E-17 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_0770 3ca4fe1952247477c8420a244ae843e4 332 SUPERFAMILY SSF53822 60 324 3.85E-64 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_0770 3ca4fe1952247477c8420a244ae843e4 332 SMART SM00354 1 71 3.8E-29 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CLOST_0770 3ca4fe1952247477c8420a244ae843e4 332 Gene3D G3DSA:1.10.260.40 1 59 9.1E-20 T 13-10-2018 CLOST_0770 3ca4fe1952247477c8420a244ae843e4 332 Gene3D G3DSA:3.40.50.2300 62 304 3.1E-77 T 13-10-2018 CLOST_0770 3ca4fe1952247477c8420a244ae843e4 332 SUPERFAMILY SSF47413 1 59 9.28E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_0770 3ca4fe1952247477c8420a244ae843e4 332 Gene3D G3DSA:3.40.50.2300 155 283 3.1E-77 T 13-10-2018 CLOST_0413 bff5845d4edec98469817312edff8782 153 Gene3D G3DSA:3.40.50.960 1 153 7.3E-64 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0413 bff5845d4edec98469817312edff8782 153 SUPERFAMILY SSF52121 3 151 1.1E-63 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0413 bff5845d4edec98469817312edff8782 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 31.969 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0413 bff5845d4edec98469817312edff8782 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 149 5.7E-58 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0413 bff5845d4edec98469817312edff8782 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 150 2.9E-60 T 13-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_2166 da4aed77efa31975f00da7c3262d9e1c 287 Gene3D G3DSA:3.40.50.300 1 287 3.0E-85 T 13-10-2018 CLOST_2166 da4aed77efa31975f00da7c3262d9e1c 287 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 4 278 1.4E-121 T 13-10-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CLOST_2166 da4aed77efa31975f00da7c3262d9e1c 287 Pfam PF00005 ABC transporter 23 173 1.5E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2166 da4aed77efa31975f00da7c3262d9e1c 287 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 20 205 7.3E-64 T 13-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 CLOST_2166 da4aed77efa31975f00da7c3262d9e1c 287 SMART SM00382 32 222 4.7E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2166 da4aed77efa31975f00da7c3262d9e1c 287 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2166 da4aed77efa31975f00da7c3262d9e1c 287 SUPERFAMILY SSF52540 5 236 3.74E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1059 10cce5027ddc64b4330c42531d1b49f8 500 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 487 8.8E-191 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 CLOST_1059 10cce5027ddc64b4330c42531d1b49f8 500 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 46 487 1.5E-159 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 CLOST_0423 0839174f1d313a082d1bda59ae2d145f 360 Gene3D G3DSA:1.10.287.470 125 230 5.8E-5 T 13-10-2018 CLOST_0423 0839174f1d313a082d1bda59ae2d145f 360 Gene3D G3DSA:2.40.30.170 252 360 5.1E-21 T 13-10-2018 CLOST_0423 0839174f1d313a082d1bda59ae2d145f 360 Gene3D G3DSA:2.40.50.100 50 98 2.2E-9 T 13-10-2018 CLOST_0423 0839174f1d313a082d1bda59ae2d145f 360 Gene3D G3DSA:2.40.30.170 39 49 2.2E-9 T 13-10-2018 CLOST_0423 0839174f1d313a082d1bda59ae2d145f 360 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 233 354 6.7E-15 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CLOST_0423 0839174f1d313a082d1bda59ae2d145f 360 SUPERFAMILY SSF111369 47 124 3.79E-5 T 13-10-2018 CLOST_0423 0839174f1d313a082d1bda59ae2d145f 360 SUPERFAMILY SSF111369 190 358 1.05E-8 T 13-10-2018 CLOST_0423 0839174f1d313a082d1bda59ae2d145f 360 Pfam PF13533 Biotin-lipoyl like 47 93 2.8E-8 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain CLOST_1754 31877dac56421845f855f3f85d374a6f 242 Gene3D G3DSA:3.40.50.150 1 162 3.3E-51 T 13-10-2018 CLOST_1754 31877dac56421845f855f3f85d374a6f 242 PIRSF PIRSF018637 1 233 2.3E-64 T 13-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CLOST_1754 31877dac56421845f855f3f85d374a6f 242 SUPERFAMILY SSF53335 6 140 1.71E-11 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1754 31877dac56421845f855f3f85d374a6f 242 Pfam PF12847 Methyltransferase domain 2 154 2.6E-53 T 13-10-2018 CLOST_2271 f964399ad959f1f87d84a02b6dce2fa2 276 Gene3D G3DSA:3.40.50.150 34 195 7.3E-22 T 13-10-2018 CLOST_2271 f964399ad959f1f87d84a02b6dce2fa2 276 Pfam PF13847 Methyltransferase domain 59 140 1.3E-15 T 13-10-2018 IPR025714 Methyltransferase domain CLOST_2271 f964399ad959f1f87d84a02b6dce2fa2 276 SUPERFAMILY SSF53335 18 201 5.43E-27 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0508 c13644da301b53d6120b2c7de569e863 942 Gene3D G3DSA:1.20.1580.10 695 832 3.3E-145 T 13-10-2018 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 Pfam PF00005 ABC transporter 626 862 2.2E-9 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 Gene3D G3DSA:1.10.8.280 286 407 5.1E-253 T 13-10-2018 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 SUPERFAMILY SSF52540 12 573 3.29E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0508 c13644da301b53d6120b2c7de569e863 942 Gene3D G3DSA:3.30.190.20 132 241 5.1E-253 T 13-10-2018 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 Gene3D G3DSA:3.40.50.300 616 938 3.3E-145 T 13-10-2018 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 SUPERFAMILY SSF52540 618 915 1.61E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0508 c13644da301b53d6120b2c7de569e863 942 Gene3D G3DSA:1.20.1580.10 92 496 5.1E-253 T 13-10-2018 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 927 0.0 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 942 22.899 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 ProSitePatterns PS00211 ABC transporters family signature. 832 846 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0508 c13644da301b53d6120b2c7de569e863 942 Gene3D G3DSA:3.40.50.300 7 599 5.1E-253 T 13-10-2018 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 SMART SM01004 1 319 2.8E-224 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 239 251 - T 13-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 239 255 3.5E-59 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 187 206 3.5E-59 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 118 132 3.5E-59 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 293 312 3.5E-59 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 264 279 3.5E-59 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 149 168 3.5E-59 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 SUPERFAMILY SSF51569 2 319 5.27E-139 T 13-10-2018 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 Pfam PF00490 Delta-aminolevulinic acid dehydratase 3 317 2.1E-145 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 Gene3D G3DSA:3.20.20.70 1 319 3.3E-145 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1000 cb0d00f5b252ef103e5c92cb4e795962 319 PIRSF PIRSF001415 1 319 1.0E-142 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CLOST_0074 320792a6068646817909e9b4f787345e 347 Gene3D G3DSA:3.40.190.10 50 315 3.4E-52 T 13-10-2018 CLOST_0074 320792a6068646817909e9b4f787345e 347 SUPERFAMILY SSF53850 46 274 3.66E-36 T 13-10-2018 CLOST_0074 320792a6068646817909e9b4f787345e 347 Gene3D G3DSA:3.40.190.10 126 231 3.4E-52 T 13-10-2018 CLOST_0074 320792a6068646817909e9b4f787345e 347 Pfam PF09084 NMT1/THI5 like 56 272 6.3E-25 T 13-10-2018 IPR015168 SsuA/THI5-like CLOST_2416 c28171f9204746ad5e37313e7eeb25b4 349 Gene3D G3DSA:3.30.420.10 180 343 4.8E-6 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_2416 c28171f9204746ad5e37313e7eeb25b4 349 Pfam PF00665 Integrase core domain 189 299 2.8E-8 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 CLOST_2416 c28171f9204746ad5e37313e7eeb25b4 349 Pfam PF13936 Helix-turn-helix domain 13 55 2.0E-11 T 13-10-2018 IPR025246 Transposase IS30-like HTH domain CLOST_2416 c28171f9204746ad5e37313e7eeb25b4 349 SUPERFAMILY SSF53098 189 341 2.85E-21 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1063 9f886c59d43657c578d00db9bc5d22a1 126 Gene3D G3DSA:3.10.120.10 49 123 4.3E-10 T 13-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily CLOST_1063 9f886c59d43657c578d00db9bc5d22a1 126 Pfam PF00173 Cytochrome b5-like Heme/Steroid binding domain 54 125 4.4E-10 T 13-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain CLOST_1063 9f886c59d43657c578d00db9bc5d22a1 126 SMART SM01117 53 125 5.1E-14 T 13-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain CLOST_1063 9f886c59d43657c578d00db9bc5d22a1 126 SUPERFAMILY SSF55856 50 114 3.14E-15 T 13-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 Gene3D G3DSA:3.40.50.450 7 387 8.5E-127 T 13-10-2018 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 Gene3D G3DSA:3.40.50.460 137 384 8.5E-127 T 13-10-2018 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 4 397 38.902 T 13-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 SUPERFAMILY SSF53784 6 386 2.75E-86 T 13-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 99 115 5.3E-5 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 170 186 5.3E-5 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 228 240 5.3E-5 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 132 149 5.3E-5 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 36 49 5.3E-5 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 PIRSF PIRSF036483 3 406 1.8E-128 T 13-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 CLOST_0922 f47bd07d10b57d67a5b35abc8498b105 406 Pfam PF00365 Phosphofructokinase 6 322 6.2E-48 T 13-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_0625 ca7cac5c5e8db3676158e18f917c6856 177 SUPERFAMILY SSF46785 12 89 3.4E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0625 ca7cac5c5e8db3676158e18f917c6856 177 Pfam PF14277 Domain of unknown function (DUF4364) 12 173 4.8E-48 T 13-10-2018 IPR025374 Protein of unknown function DUF4364 CLOST_0625 ca7cac5c5e8db3676158e18f917c6856 177 Gene3D G3DSA:1.10.10.10 13 105 2.7E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 SUPERFAMILY SSF52540 3 220 1.02E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 Gene3D G3DSA:1.10.8.60 169 224 2.8E-7 T 13-10-2018 CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 Gene3D G3DSA:3.40.50.300 1 152 9.7E-38 T 13-10-2018 CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 Pfam PF12002 MgsA AAA+ ATPase C terminal 252 416 1.4E-63 T 13-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 SUPERFAMILY SSF48019 237 417 1.87E-69 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 Pfam PF16193 AAA C-terminal domain 174 251 1.5E-21 T 13-10-2018 IPR032423 AAA C-terminal domain CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 SMART SM00382 38 154 1.0E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 Gene3D G3DSA:1.10.3710.10 330 418 6.0E-21 T 13-10-2018 CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 124 1.8E-14 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CLOST_1496 5e5d322ec08d452237c4828ec84acd02 418 Gene3D G3DSA:1.20.272.10 226 329 3.6E-42 T 13-10-2018 CLOST_2174 a662f26097f8520d70b3b4df53773dd7 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 1.4E-37 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CLOST_2174 a662f26097f8520d70b3b4df53773dd7 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.209 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CLOST_2174 a662f26097f8520d70b3b4df53773dd7 72 Gene3D G3DSA:2.40.50.140 2 71 6.2E-37 T 13-10-2018 CLOST_2174 a662f26097f8520d70b3b4df53773dd7 72 SUPERFAMILY SSF50249 1 70 1.18E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2174 a662f26097f8520d70b3b4df53773dd7 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.2E-27 T 13-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CLOST_2174 a662f26097f8520d70b3b4df53773dd7 72 SMART SM00316 4 72 4.4E-5 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_2325 eabcee8e274bc7029113312eda57a108 391 SUPERFAMILY SSF55874 237 389 6.02E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2325 eabcee8e274bc7029113312eda57a108 391 Pfam PF01590 GAF domain 40 176 2.9E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 CLOST_2325 eabcee8e274bc7029113312eda57a108 391 SMART SM00387 271 391 3.3E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_2325 eabcee8e274bc7029113312eda57a108 391 Gene3D G3DSA:3.30.450.40 37 188 3.5E-16 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_2325 eabcee8e274bc7029113312eda57a108 391 Gene3D G3DSA:3.30.565.10 222 390 3.6E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2325 eabcee8e274bc7029113312eda57a108 391 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 390 5.3E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_2325 eabcee8e274bc7029113312eda57a108 391 SUPERFAMILY SSF55781 41 175 3.71E-12 T 13-10-2018 CLOST_2325 eabcee8e274bc7029113312eda57a108 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 334 8.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2325 eabcee8e274bc7029113312eda57a108 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 348 8.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2325 eabcee8e274bc7029113312eda57a108 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 389 8.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2325 eabcee8e274bc7029113312eda57a108 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 369 8.3E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 PRINTS PR00123 ATP synthase A subunit signature 79 95 8.4E-10 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 PRINTS PR00123 ATP synthase A subunit signature 219 234 8.4E-10 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 PRINTS PR00123 ATP synthase A subunit signature 138 153 8.4E-10 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 PRINTS PR00123 ATP synthase A subunit signature 154 176 8.4E-10 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 237 13.125 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 Gene3D G3DSA:1.20.120.220 71 237 3.6E-36 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 SUPERFAMILY SSF81336 73 232 9.15E-32 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 Pfam PF00119 ATP synthase A chain 22 232 1.9E-53 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2122 c53249b0403ec3dd3f578a9b955f18da 237 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 18 233 4.9E-31 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_0895 d539196d1d2dd5949a5e8c564b2ff8ad 75 Gene3D G3DSA:1.10.1200.10 1 75 1.2E-25 T 13-10-2018 IPR036736 ACP-like superfamily CLOST_0895 d539196d1d2dd5949a5e8c564b2ff8ad 75 Pfam PF00550 Phosphopantetheine attachment site 4 71 1.4E-14 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain CLOST_0895 d539196d1d2dd5949a5e8c564b2ff8ad 75 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 75 8.1E-28 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CLOST_0895 d539196d1d2dd5949a5e8c564b2ff8ad 75 Hamap MF_01217 Acyl carrier protein [acpP]. 1 75 19.507 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CLOST_0895 d539196d1d2dd5949a5e8c564b2ff8ad 75 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 74 5.0E-8 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CLOST_0895 d539196d1d2dd5949a5e8c564b2ff8ad 75 SUPERFAMILY SSF47336 2 74 4.19E-21 T 13-10-2018 IPR036736 ACP-like superfamily CLOST_0895 d539196d1d2dd5949a5e8c564b2ff8ad 75 ProSitePatterns PS00012 Phosphopantetheine attachment site. 30 45 - T 13-10-2018 IPR006162 Phosphopantetheine attachment site CLOST_2282 baa59280749783d5a66c190e027995b9 346 Pfam PF00990 Diguanylate cyclase, GGDEF domain 180 340 1.1E-49 T 13-10-2018 IPR000160 GGDEF domain CLOST_2282 baa59280749783d5a66c190e027995b9 346 SMART SM00267 167 344 6.2E-56 T 13-10-2018 IPR000160 GGDEF domain CLOST_2282 baa59280749783d5a66c190e027995b9 346 Gene3D G3DSA:3.30.70.270 166 344 3.1E-55 T 13-10-2018 CLOST_2282 baa59280749783d5a66c190e027995b9 346 Pfam PF13426 PAS domain 44 146 1.3E-9 T 13-10-2018 IPR000014 PAS domain CLOST_2282 baa59280749783d5a66c190e027995b9 346 SUPERFAMILY SSF55073 184 343 5.34E-48 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2282 baa59280749783d5a66c190e027995b9 346 Gene3D G3DSA:3.30.450.20 37 165 4.6E-19 T 13-10-2018 CLOST_2282 baa59280749783d5a66c190e027995b9 346 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 176 344 2.0E-53 T 13-10-2018 IPR000160 GGDEF domain CLOST_2282 baa59280749783d5a66c190e027995b9 346 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 35 154 3.2E-12 T 13-10-2018 IPR000014 PAS domain CLOST_2282 baa59280749783d5a66c190e027995b9 346 SUPERFAMILY SSF55785 38 145 3.84E-13 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2182 e402f31a4ad7dd296396c9dc8164c68f 122 SUPERFAMILY SSF53137 7 120 7.66E-53 T 13-10-2018 CLOST_2182 e402f31a4ad7dd296396c9dc8164c68f 122 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 122 1.5E-43 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2182 e402f31a4ad7dd296396c9dc8164c68f 122 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 122 28.088 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2182 e402f31a4ad7dd296396c9dc8164c68f 122 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 122 1.4E-47 T 13-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2182 e402f31a4ad7dd296396c9dc8164c68f 122 Gene3D G3DSA:3.30.420.100 5 122 8.2E-46 T 13-10-2018 CLOST_0368 d602c5f03a43398fb305dc97c4086d7f 389 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 5 368 2.8E-144 T 13-10-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CLOST_0368 d602c5f03a43398fb305dc97c4086d7f 389 SUPERFAMILY SSF53756 2 377 6.03E-103 T 13-10-2018 CLOST_0368 d602c5f03a43398fb305dc97c4086d7f 389 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 368 2.2E-98 T 13-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CLOST_0368 d602c5f03a43398fb305dc97c4086d7f 389 Gene3D G3DSA:3.40.50.2000 5 367 6.1E-96 T 13-10-2018 CLOST_0368 d602c5f03a43398fb305dc97c4086d7f 389 Gene3D G3DSA:3.40.50.2000 190 355 6.1E-96 T 13-10-2018 CLOST_0215 8d17b1f6ba64eee9f66eff7d1e937ccb 411 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 201 410 5.0E-30 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CLOST_0215 8d17b1f6ba64eee9f66eff7d1e937ccb 411 Gene3D G3DSA:2.40.420.20 338 395 9.7E-45 T 13-10-2018 CLOST_0215 8d17b1f6ba64eee9f66eff7d1e937ccb 411 Gene3D G3DSA:1.10.287.470 88 219 9.7E-45 T 13-10-2018 CLOST_0215 8d17b1f6ba64eee9f66eff7d1e937ccb 411 Pfam PF13437 HlyD family secretion protein 219 322 1.4E-10 T 13-10-2018 CLOST_0215 8d17b1f6ba64eee9f66eff7d1e937ccb 411 Gene3D G3DSA:2.40.50.100 55 253 9.7E-45 T 13-10-2018 CLOST_0215 8d17b1f6ba64eee9f66eff7d1e937ccb 411 Pfam PF13533 Biotin-lipoyl like 58 103 8.6E-7 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain CLOST_0215 8d17b1f6ba64eee9f66eff7d1e937ccb 411 Gene3D G3DSA:2.40.30.170 50 337 9.7E-45 T 13-10-2018 CLOST_0215 8d17b1f6ba64eee9f66eff7d1e937ccb 411 SUPERFAMILY SSF111369 199 257 5.23E-5 T 13-10-2018 CLOST_0833 ce41328c50c6d4585df4797459df17fb 348 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 51 348 28.916 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 CLOST_0833 ce41328c50c6d4585df4797459df17fb 348 SUPERFAMILY SSF81799 161 267 1.12E-21 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 CLOST_0833 ce41328c50c6d4585df4797459df17fb 348 SUPERFAMILY SSF53335 50 347 1.21E-35 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0833 ce41328c50c6d4585df4797459df17fb 348 Gene3D G3DSA:3.40.50.150 56 345 1.0E-80 T 13-10-2018 CLOST_0833 ce41328c50c6d4585df4797459df17fb 348 PIRSF PIRSF004486 45 348 1.4E-80 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 CLOST_0833 ce41328c50c6d4585df4797459df17fb 348 Pfam PF01795 MraW methylase family 50 345 1.8E-69 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 CLOST_0833 ce41328c50c6d4585df4797459df17fb 348 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 50 345 1.1E-67 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 CLOST_0833 ce41328c50c6d4585df4797459df17fb 348 Gene3D G3DSA:1.10.150.170 159 268 1.0E-80 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 CLOST_0605 ed1a1731d1a2ca3130b3387b47f283bc 243 SMART SM00382 30 214 4.0E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0605 ed1a1731d1a2ca3130b3387b47f283bc 243 SUPERFAMILY SSF52540 3 215 5.33E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0605 ed1a1731d1a2ca3130b3387b47f283bc 243 Pfam PF00005 ABC transporter 21 165 1.5E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0605 ed1a1731d1a2ca3130b3387b47f283bc 243 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0605 ed1a1731d1a2ca3130b3387b47f283bc 243 Gene3D G3DSA:3.40.50.300 1 239 6.4E-58 T 13-10-2018 CLOST_2476 6d4aab23b34e393d0bf1f821c5158217 166 Pfam PF00186 Dihydrofolate reductase 4 165 2.5E-39 T 13-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CLOST_2476 6d4aab23b34e393d0bf1f821c5158217 166 PRINTS PR00070 Dihydrofolate reductase signature 30 38 1.1E-7 T 13-10-2018 CLOST_2476 6d4aab23b34e393d0bf1f821c5158217 166 PRINTS PR00070 Dihydrofolate reductase signature 95 109 1.1E-7 T 13-10-2018 CLOST_2476 6d4aab23b34e393d0bf1f821c5158217 166 PRINTS PR00070 Dihydrofolate reductase signature 43 54 1.1E-7 T 13-10-2018 CLOST_2476 6d4aab23b34e393d0bf1f821c5158217 166 SUPERFAMILY SSF53597 4 166 2.75E-37 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 CLOST_2476 6d4aab23b34e393d0bf1f821c5158217 166 Gene3D G3DSA:3.40.430.10 2 166 1.8E-40 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 260 7.5E-62 T 13-10-2018 CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 9.0E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 9.0E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 9.0E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 SUPERFAMILY SSF51735 16 261 1.11E-81 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 Gene3D G3DSA:3.40.50.720 4 261 6.1E-80 T 13-10-2018 CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 1.3E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 1.3E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.3E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.3E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.3E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0195 175c33d486bad8791cab53a2c42704e9 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.3E-31 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Gene3D G3DSA:3.30.70.1430 563 662 0.0 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Pfam PF00873 AcrB/AcrD/AcrF family 5 1019 1.6E-276 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Gene3D G3DSA:1.20.1640.10 509 1016 0.0 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 SUPERFAMILY SSF82693 40 134 2.62E-24 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Gene3D G3DSA:3.30.2090.10 177 267 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Gene3D G3DSA:3.30.70.1430 40 810 0.0 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Gene3D G3DSA:1.20.1640.10 10 508 0.0 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 SUPERFAMILY SSF82693 136 321 6.02E-13 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Gene3D G3DSA:3.30.70.1320 132 323 0.0 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 548 565 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 PRINTS PR00702 Acriflavin resistance protein family signature 618 632 4.5E-57 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Gene3D G3DSA:3.30.70.1440 663 859 0.0 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 SUPERFAMILY SSF82866 290 487 1.05E-43 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 Gene3D G3DSA:3.30.2090.10 714 802 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 SUPERFAMILY SSF82693 561 659 2.41E-17 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 SUPERFAMILY SSF82866 798 1021 2.88E-55 T 13-10-2018 CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 SUPERFAMILY SSF82714 715 799 1.03E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CLOST_0457 8587d246932a07886819ef5f7f1d66a9 1047 SUPERFAMILY SSF82714 182 263 1.57E-17 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CLOST_2439 cf83e8ad34723966fe70e6171c596808 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 112 9.8E-22 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 CLOST_2439 cf83e8ad34723966fe70e6171c596808 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 9.5E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_2439 cf83e8ad34723966fe70e6171c596808 223 Gene3D G3DSA:1.10.3720.10 1 221 2.7E-48 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2439 cf83e8ad34723966fe70e6171c596808 223 SUPERFAMILY SSF161098 15 203 7.72E-41 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0974 1244f39c3c10db706fcdedb84e4bb52f 204 Gene3D G3DSA:3.10.620.30 60 199 6.7E-16 T 13-10-2018 CLOST_0974 1244f39c3c10db706fcdedb84e4bb52f 204 SUPERFAMILY SSF54001 79 181 4.32E-16 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_0974 1244f39c3c10db706fcdedb84e4bb52f 204 Pfam PF01841 Transglutaminase-like superfamily 86 170 3.6E-11 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 Gene3D G3DSA:1.10.8.500 323 370 2.5E-5 T 13-10-2018 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 SMART SM00304 325 377 8.8E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 SMART SM00283 399 681 4.5E-46 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 Pfam PF02743 Cache domain 36 249 4.6E-29 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 Pfam PF00672 HAMP domain 326 371 1.6E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 Gene3D G3DSA:3.30.450.20 78 180 6.8E-31 T 13-10-2018 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 Gene3D G3DSA:1.10.287.950 371 681 6.3E-60 T 13-10-2018 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 463 614 1.6E-34 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 SUPERFAMILY SSF103190 69 190 5.57E-7 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 Gene3D G3DSA:3.30.450.20 181 298 6.8E-31 T 13-10-2018 CLOST_0032 5a0d2548fc6d08125c6a9f7ab7aabdf5 682 SUPERFAMILY SSF58104 345 681 1.44E-60 T 13-10-2018 CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 Gene3D G3DSA:3.40.50.300 289 515 3.9E-42 T 13-10-2018 CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 Pfam PF12848 ABC transporter 230 315 9.6E-22 T 13-10-2018 IPR032781 ABC-transporter extension domain CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 SMART SM00382 28 236 1.3E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 SMART SM00382 349 518 1.0E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 Gene3D G3DSA:3.40.50.300 2 285 1.2E-66 T 13-10-2018 CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 Pfam PF00005 ABC transporter 20 191 5.5E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 SUPERFAMILY SSF52540 5 246 1.83E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 SUPERFAMILY SSF52540 307 507 3.38E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2288 6cd0ab6b276544fd8cd629466e301ae3 518 Pfam PF00005 ABC transporter 341 469 1.5E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1243 89d90444f88c940e7d620cbc24de2bd7 334 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 327 1.7E-103 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CLOST_1243 89d90444f88c940e7d620cbc24de2bd7 334 SMART SM01329 3 327 1.7E-163 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CLOST_1243 89d90444f88c940e7d620cbc24de2bd7 334 SUPERFAMILY SSF53659 2 331 1.56E-118 T 13-10-2018 CLOST_1243 89d90444f88c940e7d620cbc24de2bd7 334 Gene3D G3DSA:3.40.718.10 1 334 2.7E-134 T 13-10-2018 CLOST_1243 89d90444f88c940e7d620cbc24de2bd7 334 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 223 242 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 SUPERFAMILY SSF69055 293 387 2.09E-31 T 13-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 SUPERFAMILY SSF55347 128 266 6.54E-61 T 13-10-2018 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 Gene3D G3DSA:1.10.1740.10 305 388 4.4E-27 T 13-10-2018 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 134 4.5E-45 T 13-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 386 4.6E-153 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 PIRSF PIRSF006205 1 389 7.8E-164 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 Gene3D G3DSA:3.40.50.720 1 152 5.0E-52 T 13-10-2018 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 SUPERFAMILY SSF51735 2 152 1.6E-43 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 384 46.68 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 148 231 7.9E-41 T 13-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 CLOST_1698 d51db778402d6ed185eb0de82f19f45b 389 Pfam PF13288 DXP reductoisomerase C-terminal domain 263 379 1.3E-39 T 13-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 SMART SM00357 2 65 3.9E-30 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 PRINTS PR00050 Cold shock protein signature 23 32 3.6E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 PRINTS PR00050 Cold shock protein signature 3 18 3.6E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 PRINTS PR00050 Cold shock protein signature 38 56 3.6E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 Gene3D G3DSA:2.40.50.140 1 64 1.9E-30 T 13-10-2018 CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 63 5.1E-32 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 13-10-2018 IPR019844 Cold-shock conserved site CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 SUPERFAMILY SSF50249 2 63 1.62E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2266 9943b0c132c885e39c9fa6b218f51a9a 65 PIRSF PIRSF002599 1 65 7.6E-24 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 CLOST_1043 06bdab4c7e36b656e5037e5dd008fd28 328 SUPERFAMILY SSF47413 1 67 1.37E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_1043 06bdab4c7e36b656e5037e5dd008fd28 328 Pfam PF01381 Helix-turn-helix 9 61 1.5E-15 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1043 06bdab4c7e36b656e5037e5dd008fd28 328 Gene3D G3DSA:1.10.260.40 1 64 3.9E-21 T 13-10-2018 CLOST_1043 06bdab4c7e36b656e5037e5dd008fd28 328 SMART SM00530 6 61 1.7E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 SUPERFAMILY SSF49785 49 190 2.84E-14 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Gene3D G3DSA:2.60.40.10 699 791 1.3E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Gene3D G3DSA:2.60.40.10 522 609 7.9E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Gene3D G3DSA:2.60.40.3630 803 874 5.7E-7 T 13-10-2018 CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Pfam PF00395 S-layer homology domain 1140 1181 1.4E-6 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Pfam PF00395 S-layer homology domain 1079 1121 3.7E-9 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Pfam PF00395 S-layer homology domain 1207 1250 2.3E-7 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Gene3D G3DSA:2.60.120.260 32 189 1.5E-24 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Pfam PF05345 Putative Ig domain 554 593 4.6E-7 T 13-10-2018 IPR008009 Putative Ig CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Pfam PF05345 Putative Ig domain 740 778 5.4E-7 T 13-10-2018 IPR008009 Putative Ig CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 SUPERFAMILY SSF49313 526 609 2.75E-6 T 13-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 Pfam PF00754 F5/8 type C domain 59 185 1.0E-11 T 13-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CLOST_2452 480e64d96da656eb53b8bd3660c934de 1260 SUPERFAMILY SSF49313 740 795 2.04E-5 T 13-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 CLOST_1264 92943e77fa96cfb3922a833f98d3b259 405 SUPERFAMILY SSF116734 194 402 4.91E-32 T 13-10-2018 CLOST_1264 92943e77fa96cfb3922a833f98d3b259 405 Gene3D G3DSA:3.90.220.20 214 352 1.0E-53 T 13-10-2018 CLOST_1264 92943e77fa96cfb3922a833f98d3b259 405 Gene3D G3DSA:1.10.287.1120 142 399 1.0E-53 T 13-10-2018 CLOST_1264 92943e77fa96cfb3922a833f98d3b259 405 Pfam PF01420 Type I restriction modification DNA specificity domain 210 374 4.3E-9 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CLOST_1264 92943e77fa96cfb3922a833f98d3b259 405 Pfam PF01420 Type I restriction modification DNA specificity domain 16 174 1.5E-13 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CLOST_1264 92943e77fa96cfb3922a833f98d3b259 405 Gene3D G3DSA:3.90.220.20 58 402 1.0E-53 T 13-10-2018 CLOST_1264 92943e77fa96cfb3922a833f98d3b259 405 SUPERFAMILY SSF116734 3 195 1.14E-31 T 13-10-2018 CLOST_0174 792c158ebb09d8e56cf696111eca440c 499 Gene3D G3DSA:2.60.40.1180 420 499 6.5E-7 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta CLOST_0174 792c158ebb09d8e56cf696111eca440c 499 SUPERFAMILY SSF51445 34 414 1.0E-67 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily CLOST_0174 792c158ebb09d8e56cf696111eca440c 499 Gene3D G3DSA:3.20.20.80 38 391 1.3E-81 T 13-10-2018 CLOST_0174 792c158ebb09d8e56cf696111eca440c 499 SUPERFAMILY SSF51011 420 497 6.48E-6 T 13-10-2018 CLOST_0174 792c158ebb09d8e56cf696111eca440c 499 Pfam PF00128 Alpha amylase, catalytic domain 55 389 2.3E-47 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CLOST_0174 792c158ebb09d8e56cf696111eca440c 499 SMART SM00642 48 408 5.0E-32 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CLOST_0174 792c158ebb09d8e56cf696111eca440c 499 Gene3D G3DSA:3.90.400.10 145 210 1.3E-81 T 13-10-2018 CLOST_1616 f5a3eb7083500c089d14b250c3b84ff0 428 SUPERFAMILY SSF102114 40 195 1.86E-13 T 13-10-2018 CLOST_1616 f5a3eb7083500c089d14b250c3b84ff0 428 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 5 409 2.2E-186 T 13-10-2018 IPR023874 DNA modification/repair radical SAM protein, putative CLOST_1616 f5a3eb7083500c089d14b250c3b84ff0 428 Gene3D G3DSA:3.20.20.70 48 202 8.2E-7 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1616 f5a3eb7083500c089d14b250c3b84ff0 428 Gene3D G3DSA:1.10.150.320 305 370 2.3E-7 T 13-10-2018 CLOST_1616 f5a3eb7083500c089d14b250c3b84ff0 428 Pfam PF12836 Helix-hairpin-helix motif 320 361 4.7E-7 T 13-10-2018 CLOST_1616 f5a3eb7083500c089d14b250c3b84ff0 428 SUPERFAMILY SSF47781 300 376 1.19E-13 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 SMART SM00861 354 524 1.1E-54 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 Pfam PF02780 Transketolase, C-terminal domain 543 652 1.1E-8 T 13-10-2018 IPR033248 Transketolase, C-terminal domain CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 SUPERFAMILY SSF52518 4 324 9.11E-113 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 1.5E-148 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 SUPERFAMILY SSF52518 348 526 1.18E-59 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 TIGRFAM TIGR00232 tktlase_bact: transketolase 7 659 2.5E-277 T 13-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 Gene3D G3DSA:3.40.50.920 535 661 1.0E-41 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 Gene3D G3DSA:3.40.50.970 334 534 2.6E-65 T 13-10-2018 CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 Pfam PF02779 Transketolase, pyrimidine binding domain 353 523 1.8E-38 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 Gene3D G3DSA:3.40.50.970 1 333 1.4E-124 T 13-10-2018 CLOST_1766 87f6b5c1859f8d12b9028aaba0ef00a7 661 SUPERFAMILY SSF52922 530 661 2.0E-40 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_2200 6d08f1d8bba1913d5fdbbfdcda76a3f8 235 SUPERFAMILY SSF52540 2 232 3.08E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2200 6d08f1d8bba1913d5fdbbfdcda76a3f8 235 Gene3D G3DSA:3.40.50.300 1 234 2.5E-63 T 13-10-2018 CLOST_2200 6d08f1d8bba1913d5fdbbfdcda76a3f8 235 SMART SM00382 26 232 0.0056 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2200 6d08f1d8bba1913d5fdbbfdcda76a3f8 235 PIRSF PIRSF039137 1 234 9.0E-108 T 13-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CLOST_2200 6d08f1d8bba1913d5fdbbfdcda76a3f8 235 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2200 6d08f1d8bba1913d5fdbbfdcda76a3f8 235 Pfam PF00005 ABC transporter 17 161 1.7E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0869 d010ce06e047982c51fedc2f849d4b0a 227 SMART SM00448 2 112 6.6E-42 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0869 d010ce06e047982c51fedc2f849d4b0a 227 SUPERFAMILY SSF46894 122 223 1.08E-28 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_0869 d010ce06e047982c51fedc2f849d4b0a 227 Pfam PF00072 Response regulator receiver domain 4 112 2.2E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0869 d010ce06e047982c51fedc2f849d4b0a 227 SMART SM00862 148 223 4.5E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_0869 d010ce06e047982c51fedc2f849d4b0a 227 Gene3D G3DSA:3.40.50.2300 1 128 2.1E-37 T 13-10-2018 CLOST_0869 d010ce06e047982c51fedc2f849d4b0a 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 1.5E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_0869 d010ce06e047982c51fedc2f849d4b0a 227 SUPERFAMILY SSF52172 1 125 1.71E-39 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0869 d010ce06e047982c51fedc2f849d4b0a 227 Gene3D G3DSA:1.10.10.10 129 227 1.7E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1466 62ec7826281d9650a4a69fe646757bd2 278 Gene3D G3DSA:3.40.1010.20 5 272 2.4E-93 T 13-10-2018 CLOST_1466 62ec7826281d9650a4a69fe646757bd2 278 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 278 29.806 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CLOST_1466 62ec7826281d9650a4a69fe646757bd2 278 Gene3D G3DSA:3.40.50.11270 12 94 2.4E-93 T 13-10-2018 CLOST_1466 62ec7826281d9650a4a69fe646757bd2 278 Gene3D G3DSA:3.40.1010.20 95 193 2.4E-93 T 13-10-2018 CLOST_1466 62ec7826281d9650a4a69fe646757bd2 278 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 277 6.5E-89 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CLOST_1466 62ec7826281d9650a4a69fe646757bd2 278 Pfam PF02401 LytB protein 3 275 2.8E-89 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CLOST_0597 c6ffce78a9296eea204be76a62f6b493 473 Gene3D G3DSA:3.40.50.2000 252 422 4.1E-23 T 13-10-2018 CLOST_0597 c6ffce78a9296eea204be76a62f6b493 473 SUPERFAMILY SSF53756 212 416 1.67E-13 T 13-10-2018 CLOST_0597 c6ffce78a9296eea204be76a62f6b493 473 Pfam PF00534 Glycosyl transferases group 1 297 421 9.6E-14 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 CLOST_0597 c6ffce78a9296eea204be76a62f6b493 473 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 17 220 2.2E-16 T 13-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 526 7.7E-256 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 Gene3D G3DSA:3.30.260.10 135 408 3.5E-233 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.652 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 SUPERFAMILY SSF52029 183 374 3.29E-84 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 PRINTS PR00298 60kDa chaperonin signature 26 52 2.5E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 PRINTS PR00298 60kDa chaperonin signature 266 289 2.5E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 PRINTS PR00298 60kDa chaperonin signature 396 417 2.5E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 PRINTS PR00298 60kDa chaperonin signature 82 109 2.5E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 PRINTS PR00298 60kDa chaperonin signature 348 373 2.5E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 13-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 SUPERFAMILY SSF48592 6 521 6.87E-77 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 SUPERFAMILY SSF54849 137 205 3.66E-27 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 Gene3D G3DSA:3.50.7.10 190 370 3.5E-233 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 1.5E-102 T 13-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CLOST_0286 d45fe4c75415906acbd2c358a12a583c 541 Gene3D G3DSA:1.10.560.10 7 521 3.5E-233 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 Gene3D G3DSA:3.40.1390.10 3 100 1.2E-23 T 13-10-2018 CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 Gene3D G3DSA:3.40.1190.10 101 345 1.7E-69 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 SUPERFAMILY SSF53623 101 340 1.31E-54 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 Pfam PF08245 Mur ligase middle domain 110 322 3.2E-43 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 SUPERFAMILY SSF63418 18 101 2.22E-19 T 13-10-2018 IPR035911 MurE/MurF, N-terminal CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 Pfam PF01225 Mur ligase family, catalytic domain 26 73 8.3E-8 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 23 477 2.9E-83 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 Gene3D G3DSA:3.90.190.20 346 502 1.6E-8 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_1592 753d8a0dc1650e57e42ab6d0c88e6774 516 SUPERFAMILY SSF53244 341 487 1.41E-11 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_1454 21465f415876345ec6ab655da9e64393 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.0E-21 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1454 21465f415876345ec6ab655da9e64393 296 SUPERFAMILY SSF53850 89 295 5.31E-30 T 13-10-2018 CLOST_1454 21465f415876345ec6ab655da9e64393 296 Pfam PF03466 LysR substrate binding domain 89 291 4.0E-31 T 13-10-2018 IPR005119 LysR, substrate-binding CLOST_1454 21465f415876345ec6ab655da9e64393 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.8E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1454 21465f415876345ec6ab655da9e64393 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.8E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1454 21465f415876345ec6ab655da9e64393 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.8E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1454 21465f415876345ec6ab655da9e64393 296 Gene3D G3DSA:3.40.190.290 90 294 2.3E-31 T 13-10-2018 CLOST_1454 21465f415876345ec6ab655da9e64393 296 SUPERFAMILY SSF46785 1 82 2.4E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1454 21465f415876345ec6ab655da9e64393 296 Gene3D G3DSA:1.10.10.10 1 88 1.2E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1432 84ba8d788b05ff9ebcd1d91b7f02a983 382 SUPERFAMILY SSF53383 3 378 2.55E-93 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1432 84ba8d788b05ff9ebcd1d91b7f02a983 382 Gene3D G3DSA:3.90.1150.10 252 377 4.0E-27 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1432 84ba8d788b05ff9ebcd1d91b7f02a983 382 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 373 1.8E-82 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_1432 84ba8d788b05ff9ebcd1d91b7f02a983 382 Gene3D G3DSA:3.40.640.10 1 250 2.0E-74 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1432 84ba8d788b05ff9ebcd1d91b7f02a983 382 PIRSF PIRSF000390 1 381 2.2E-94 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_2223 ec6173592602db31ce0a4324ca641ae0 256 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 2 221 3.0E-59 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 CLOST_2223 ec6173592602db31ce0a4324ca641ae0 256 Pfam PF02511 Thymidylate synthase complementing protein 4 217 3.9E-70 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 CLOST_2223 ec6173592602db31ce0a4324ca641ae0 256 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 231 31.028 T 13-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 CLOST_2223 ec6173592602db31ce0a4324ca641ae0 256 Gene3D G3DSA:3.30.1360.170 1 223 4.0E-70 T 13-10-2018 CLOST_2223 ec6173592602db31ce0a4324ca641ae0 256 SUPERFAMILY SSF69796 1 231 1.24E-64 T 13-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 CLOST_0502 95642904367a9526941d3ad3a1c889ad 217 SUPERFAMILY SSF54913 8 99 6.74E-7 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CLOST_0502 95642904367a9526941d3ad3a1c889ad 217 Pfam PF00543 Nitrogen regulatory protein P-II 124 216 7.1E-7 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CLOST_0502 95642904367a9526941d3ad3a1c889ad 217 SMART SM00938 123 216 0.0017 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CLOST_0502 95642904367a9526941d3ad3a1c889ad 217 Gene3D G3DSA:3.30.70.120 119 215 1.8E-21 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CLOST_0502 95642904367a9526941d3ad3a1c889ad 217 Gene3D G3DSA:3.30.70.120 7 101 1.0E-6 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CLOST_0502 95642904367a9526941d3ad3a1c889ad 217 SUPERFAMILY SSF54913 121 216 1.84E-19 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 Gene3D G3DSA:2.40.50.140 1 64 1.2E-19 T 13-10-2018 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 199 28.006 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 195 5.1E-40 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 Pfam PF01330 RuvA N terminal domain 1 59 1.6E-18 T 13-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 Gene3D G3DSA:1.10.150.20 66 137 6.2E-23 T 13-10-2018 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 Gene3D G3DSA:1.10.8.10 146 199 1.8E-14 T 13-10-2018 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 SUPERFAMILY SSF50249 1 62 8.0E-14 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 SMART SM00278 72 91 660.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 SMART SM00278 107 126 0.068 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 Pfam PF07499 RuvA, C-terminal domain 152 195 6.0E-10 T 13-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 Pfam PF14520 Helix-hairpin-helix domain 71 129 3.8E-16 T 13-10-2018 CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 SUPERFAMILY SSF46929 151 198 2.09E-9 T 13-10-2018 IPR036267 RuvA, C-terminal domain superfamily CLOST_1317 89fe5a1832bd6978f25e266ad0925852 199 SUPERFAMILY SSF47781 65 134 8.9E-18 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_0275 75ea1e9e5ae8487ecabb12ccc07a6eb0 278 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 2 258 4.7E-68 T 13-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_0275 75ea1e9e5ae8487ecabb12ccc07a6eb0 278 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 13 248 2.9E-28 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0275 75ea1e9e5ae8487ecabb12ccc07a6eb0 278 Gene3D G3DSA:3.20.20.70 1 278 1.2E-82 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0275 75ea1e9e5ae8487ecabb12ccc07a6eb0 278 SMART SM00934 13 261 1.0E-29 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0275 75ea1e9e5ae8487ecabb12ccc07a6eb0 278 SUPERFAMILY SSF51366 6 251 3.7E-59 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CLOST_0275 75ea1e9e5ae8487ecabb12ccc07a6eb0 278 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 13-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_1611 a6755e24c461bfc5f730ca40de164d31 302 Gene3D G3DSA:3.40.50.300 1 233 1.3E-55 T 13-10-2018 CLOST_1611 a6755e24c461bfc5f730ca40de164d31 302 Pfam PF00005 ABC transporter 21 158 2.2E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1611 a6755e24c461bfc5f730ca40de164d31 302 SUPERFAMILY SSF52540 7 221 1.55E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1611 a6755e24c461bfc5f730ca40de164d31 302 SMART SM00382 29 207 8.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0925 df0d4e106d25c4c3c06cdde6f5aa6470 272 Pfam PF13411 MerR HTH family regulatory protein 6 73 2.9E-15 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_0925 df0d4e106d25c4c3c06cdde6f5aa6470 272 Gene3D G3DSA:3.20.80.10 188 270 6.1E-10 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily CLOST_0925 df0d4e106d25c4c3c06cdde6f5aa6470 272 Gene3D G3DSA:1.10.1660.10 3 153 1.7E-29 T 13-10-2018 CLOST_0925 df0d4e106d25c4c3c06cdde6f5aa6470 272 SUPERFAMILY SSF55136 122 269 2.44E-22 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily CLOST_0925 df0d4e106d25c4c3c06cdde6f5aa6470 272 Pfam PF06445 GyrI-like small molecule binding domain 183 268 3.7E-9 T 13-10-2018 IPR029442 GyrI-like small molecule binding domain CLOST_0925 df0d4e106d25c4c3c06cdde6f5aa6470 272 SMART SM00422 5 74 1.5E-19 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_0925 df0d4e106d25c4c3c06cdde6f5aa6470 272 SMART SM00871 119 269 2.7E-6 T 13-10-2018 IPR010499 Bacterial transcription activator, effector binding CLOST_0925 df0d4e106d25c4c3c06cdde6f5aa6470 272 SUPERFAMILY SSF46955 5 109 1.39E-24 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily CLOST_0362 b70af1669800850a89f5061bd06ba9e9 326 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 308 8.3E-72 T 13-10-2018 IPR016040 NAD(P)-binding domain CLOST_0362 b70af1669800850a89f5061bd06ba9e9 326 SUPERFAMILY SSF51735 2 320 5.88E-85 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0362 b70af1669800850a89f5061bd06ba9e9 326 TIGRFAM TIGR04180 EDH_00030: NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family 5 299 1.6E-157 T 13-10-2018 IPR026390 NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family CLOST_0362 b70af1669800850a89f5061bd06ba9e9 326 Gene3D G3DSA:3.90.25.10 185 315 2.1E-86 T 13-10-2018 CLOST_0362 b70af1669800850a89f5061bd06ba9e9 326 Gene3D G3DSA:3.40.50.720 5 302 2.1E-86 T 13-10-2018 CLOST_1085 15f495fdfe209977e0537c40a7b80b50 127 Pfam PF12646 Domain of unknown function (DUF3783) 64 119 4.1E-17 T 13-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 CLOST_2184 d690689cf04b29d217ef097502e12a5f 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.073 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2184 d690689cf04b29d217ef097502e12a5f 132 Gene3D G3DSA:3.30.1490.10 75 132 4.1E-25 T 13-10-2018 CLOST_2184 d690689cf04b29d217ef097502e12a5f 132 Pfam PF00410 Ribosomal protein S8 5 132 4.2E-52 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2184 d690689cf04b29d217ef097502e12a5f 132 Gene3D G3DSA:3.30.1370.30 4 74 4.4E-31 T 13-10-2018 CLOST_2184 d690689cf04b29d217ef097502e12a5f 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2184 d690689cf04b29d217ef097502e12a5f 132 SUPERFAMILY SSF56047 3 132 3.27E-47 T 13-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_0832 212301e553224373844c57b63619e161 502 Gene3D G3DSA:3.40.140.40 342 494 1.3E-49 T 13-10-2018 CLOST_0832 212301e553224373844c57b63619e161 502 Hamap MF_01567 UPF0371 protein . 1 502 56.559 T 13-10-2018 IPR014999 Uncharacterised protein family UPF0371 CLOST_0832 212301e553224373844c57b63619e161 502 Gene3D G3DSA:1.20.1570.10 206 334 2.4E-165 T 13-10-2018 CLOST_0832 212301e553224373844c57b63619e161 502 PIRSF PIRSF033132 1 502 4.9E-256 T 13-10-2018 IPR014999 Uncharacterised protein family UPF0371 CLOST_0832 212301e553224373844c57b63619e161 502 Pfam PF08903 Domain of unknown function (DUF1846) 3 499 4.0E-236 T 13-10-2018 IPR014999 Uncharacterised protein family UPF0371 CLOST_0832 212301e553224373844c57b63619e161 502 Gene3D G3DSA:3.10.630.10 3 284 2.4E-165 T 13-10-2018 CLOST_1092 29362b72be72b1ab90d050678ff12a66 178 SUPERFAMILY SSF55729 11 175 1.72E-26 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1092 29362b72be72b1ab90d050678ff12a66 178 Pfam PF00583 Acetyltransferase (GNAT) family 38 151 8.8E-14 T 13-10-2018 IPR000182 GNAT domain CLOST_1092 29362b72be72b1ab90d050678ff12a66 178 Gene3D G3DSA:3.40.630.30 10 178 7.5E-34 T 13-10-2018 CLOST_1306 cb5f4b232ccffa1d88d265d611c9df1f 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 5.0E-70 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CLOST_1306 cb5f4b232ccffa1d88d265d611c9df1f 170 SUPERFAMILY SSF53271 2 167 2.98E-49 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_1306 cb5f4b232ccffa1d88d265d611c9df1f 170 Pfam PF00156 Phosphoribosyl transferase domain 37 140 1.2E-13 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOST_1306 cb5f4b232ccffa1d88d265d611c9df1f 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.743 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CLOST_1306 cb5f4b232ccffa1d88d265d611c9df1f 170 Gene3D G3DSA:3.40.50.2020 1 170 1.3E-59 T 13-10-2018 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Gene3D G3DSA:3.90.640.50 56 128 6.7E-93 T 13-10-2018 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 33 719 3.0E-205 T 13-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 722 1025 1.5E-66 T 13-10-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Gene3D G3DSA:1.10.10.2110 789 830 3.3E-78 T 13-10-2018 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 ProDom PD047574 TYPE I RESTRICTION HYDROLASE DEOXYRIBONUCLEASE SITE-SPECIFIC HSDR ENZYME SYSTEM ENDONUCLEASE 831 866 2.0E-8 T 13-10-2018 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Gene3D G3DSA:1.20.58.2040 726 879 3.3E-78 T 13-10-2018 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Pfam PF04851 Type III restriction enzyme, res subunit 272 439 2.5E-38 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 SMART SM00487 268 478 5.4E-13 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Gene3D G3DSA:3.40.50.300 462 725 5.9E-105 T 13-10-2018 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 SUPERFAMILY SSF52540 229 440 5.99E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 29 219 1.7E-47 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Gene3D G3DSA:3.90.1570.50 29 264 6.7E-93 T 13-10-2018 CLOST_1968 ee993eafb905ff8783c801847ec86adf 1032 Gene3D G3DSA:3.40.50.300 271 461 1.4E-73 T 13-10-2018 CLOST_0517 7419355c8670e60c209e41ff8b455dc0 1526 SUPERFAMILY SSF49373 1134 1189 8.63E-6 T 13-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments CLOST_0517 7419355c8670e60c209e41ff8b455dc0 1526 Pfam PF00395 S-layer homology domain 1468 1510 1.8E-8 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0517 7419355c8670e60c209e41ff8b455dc0 1526 Pfam PF00395 S-layer homology domain 1343 1381 1.4E-9 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0517 7419355c8670e60c209e41ff8b455dc0 1526 Pfam PF00395 S-layer homology domain 1402 1445 1.5E-11 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0517 7419355c8670e60c209e41ff8b455dc0 1526 Pfam PF16640 Bacterial Ig-like domain (group 3) 1032 1119 8.8E-9 T 13-10-2018 IPR032109 Bacterial Ig-like domain (group 3) CLOST_0517 7419355c8670e60c209e41ff8b455dc0 1526 Pfam PF16640 Bacterial Ig-like domain (group 3) 761 845 1.3E-11 T 13-10-2018 IPR032109 Bacterial Ig-like domain (group 3) CLOST_0517 7419355c8670e60c209e41ff8b455dc0 1526 Gene3D G3DSA:2.60.40.1080 1117 1196 4.6E-6 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 Gene3D G3DSA:3.50.30.20 1 146 5.8E-59 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 179 193 2.4E-32 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 218 232 2.4E-32 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 290 301 2.4E-32 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 248 264 2.4E-32 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 265 282 2.4E-32 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 SUPERFAMILY SSF52317 175 356 4.59E-57 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_2428 844427dba5cd64319f95c7d179491286 360 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 356 2.0E-142 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00097 Anthranilate synthase component II signature 221 230 4.4E-6 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00097 Anthranilate synthase component II signature 331 344 4.4E-6 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00097 Anthranilate synthase component II signature 248 259 4.4E-6 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 Pfam PF00117 Glutamine amidotransferase class-I 181 354 6.0E-45 T 13-10-2018 IPR017926 Glutamine amidotransferase CLOST_2428 844427dba5cd64319f95c7d179491286 360 Gene3D G3DSA:3.40.50.880 147 358 7.3E-64 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_2428 844427dba5cd64319f95c7d179491286 360 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 360 47.001 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2428 844427dba5cd64319f95c7d179491286 360 SUPERFAMILY SSF52021 1 145 2.48E-57 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2428 844427dba5cd64319f95c7d179491286 360 SMART SM01097 1 131 8.6E-89 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 331 344 5.0E-11 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 248 259 5.0E-11 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 221 230 5.0E-11 T 13-10-2018 CLOST_2428 844427dba5cd64319f95c7d179491286 360 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 8.5E-55 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 SMART SM00267 336 510 1.4E-17 T 13-10-2018 IPR000160 GGDEF domain CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 Gene3D G3DSA:1.20.1480.50 266 348 3.0E-8 T 13-10-2018 CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 Pfam PF00563 EAL domain 527 761 6.7E-67 T 13-10-2018 IPR001633 EAL domain CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 Pfam PF02743 Cache domain 38 262 6.3E-20 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 SUPERFAMILY SSF141868 526 773 3.14E-81 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 Pfam PF00990 Diguanylate cyclase, GGDEF domain 351 505 1.5E-22 T 13-10-2018 IPR000160 GGDEF domain CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 SUPERFAMILY SSF55073 356 512 1.33E-25 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 SMART SM00304 299 351 1.4E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 Gene3D G3DSA:3.20.20.450 524 773 4.2E-89 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 Pfam PF00672 HAMP domain 299 346 4.6E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 Gene3D G3DSA:3.30.70.270 349 523 1.4E-28 T 13-10-2018 CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 SMART SM00052 520 766 3.6E-92 T 13-10-2018 IPR001633 EAL domain CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 Gene3D G3DSA:3.30.450.20 143 265 2.5E-15 T 13-10-2018 CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 SUPERFAMILY SSF158472 299 348 1.23E-6 T 13-10-2018 CLOST_0125 d1b1462be558a6b786e9ffc6c9a0dbcd 775 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 347 508 5.0E-19 T 13-10-2018 IPR000160 GGDEF domain CLOST_1330 74f0e86448e400c5346782ee80fb4c84 219 SUPERFAMILY SSF53335 34 212 4.87E-35 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1330 74f0e86448e400c5346782ee80fb4c84 219 Pfam PF01596 O-methyltransferase 27 212 3.2E-26 T 13-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CLOST_1330 74f0e86448e400c5346782ee80fb4c84 219 Gene3D G3DSA:3.40.50.150 10 214 8.6E-55 T 13-10-2018 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 1 316 4.2E-108 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 1 316 36.284 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 Gene3D G3DSA:3.20.20.70 1 316 4.0E-91 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 SMART SM00729 10 212 4.2E-21 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 SUPERFAMILY SSF102114 3 274 9.29E-74 T 13-10-2018 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 Pfam PF06463 Molybdenum Cofactor Synthesis C 179 300 5.4E-33 T 13-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 16 27 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 Pfam PF13353 4Fe-4S single cluster domain 20 119 4.7E-12 T 13-10-2018 CLOST_1661 b74e4a9443c3525df429a7dcf91c2d01 316 Pfam PF04055 Radical SAM superfamily 14 173 1.4E-32 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1995 6e1299703ab0f6743d0c5c4c29483e6b 484 SUPERFAMILY SSF56322 31 479 1.83E-130 T 13-10-2018 IPR005801 ADC synthase GO:0009058 CLOST_1995 6e1299703ab0f6743d0c5c4c29483e6b 484 Pfam PF04715 Anthranilate synthase component I, N terminal region 31 166 7.4E-23 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1995 6e1299703ab0f6743d0c5c4c29483e6b 484 Pfam PF00425 chorismate binding enzyme 216 470 1.4E-90 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CLOST_1995 6e1299703ab0f6743d0c5c4c29483e6b 484 Gene3D G3DSA:3.60.120.10 3 483 2.0E-144 T 13-10-2018 IPR005801 ADC synthase GO:0009058 CLOST_1995 6e1299703ab0f6743d0c5c4c29483e6b 484 PRINTS PR00095 Anthranilate synthase component I signature 412 426 3.1E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1995 6e1299703ab0f6743d0c5c4c29483e6b 484 PRINTS PR00095 Anthranilate synthase component I signature 332 345 3.1E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1995 6e1299703ab0f6743d0c5c4c29483e6b 484 PRINTS PR00095 Anthranilate synthase component I signature 318 331 3.1E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1995 6e1299703ab0f6743d0c5c4c29483e6b 484 PRINTS PR00095 Anthranilate synthase component I signature 427 441 3.1E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 165 34.403 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 Gene3D G3DSA:3.30.230.10 76 168 2.6E-33 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 ProSitePatterns PS00585 Ribosomal protein S5 signature. 30 62 - T 13-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 Gene3D G3DSA:3.30.160.20 4 75 4.9E-33 T 13-10-2018 CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 12 165 1.3E-65 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 SUPERFAMILY SSF54211 82 161 4.8E-24 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 Pfam PF00333 Ribosomal protein S5, N-terminal domain 14 77 1.7E-31 T 13-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 Pfam PF03719 Ribosomal protein S5, C-terminal domain 88 159 1.9E-28 T 13-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CLOST_2181 68d2680561a00f1e2faccee581a45c8c 168 SUPERFAMILY SSF54768 10 78 1.0E-24 T 13-10-2018 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 Gene3D G3DSA:1.10.287.180 5 79 2.4E-26 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 21 52 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 6 163 29.19 T 13-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 87 163 8.9E-23 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 10 162 7.2E-51 T 13-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 Gene3D G3DSA:3.10.50.30 81 164 1.1E-23 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 SUPERFAMILY SSF46557 6 80 9.42E-24 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 128 144 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 PIRSF PIRSF006092 3 164 6.4E-47 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 SUPERFAMILY SSF54534 85 163 1.31E-17 T 13-10-2018 CLOST_0951 c34b256a80330bf4f97d2209e5a017d4 164 Pfam PF03449 Transcription elongation factor, N-terminal 8 78 5.6E-27 T 13-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CLOST_2461 3737b7eae7935b0a2770dceb7b952878 280 Pfam PF14512 Putative TM nitroreductase 7 245 1.4E-38 T 13-10-2018 IPR029478 Putative nitroreductase TM1586 CLOST_2461 3737b7eae7935b0a2770dceb7b952878 280 Gene3D G3DSA:3.40.109.10 1 133 1.1E-25 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_2461 3737b7eae7935b0a2770dceb7b952878 280 SUPERFAMILY SSF55469 8 243 5.96E-21 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_2461 3737b7eae7935b0a2770dceb7b952878 280 Gene3D G3DSA:3.40.109.30 160 262 8.0E-7 T 13-10-2018 CLOST_0867 979af120133658e6e913ef49f3128e19 213 Hamap MF_01114 Regulatory protein RecX [recX]. 43 211 13.982 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 CLOST_0867 979af120133658e6e913ef49f3128e19 213 Pfam PF02631 RecX family 85 208 2.0E-22 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 CLOST_0867 979af120133658e6e913ef49f3128e19 213 Gene3D G3DSA:1.10.10.10 154 213 1.1E-9 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0867 979af120133658e6e913ef49f3128e19 213 Gene3D G3DSA:1.10.10.10 109 152 2.9E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0867 979af120133658e6e913ef49f3128e19 213 Gene3D G3DSA:1.10.10.2800 4 108 1.0E-12 T 13-10-2018 CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 Gene3D G3DSA:3.30.70.270 366 527 4.7E-43 T 13-10-2018 CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 Pfam PF02743 Cache domain 46 302 5.9E-13 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 SMART SM00267 354 527 4.5E-39 T 13-10-2018 IPR000160 GGDEF domain CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 SUPERFAMILY SSF103190 212 313 2.12E-20 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 364 522 6.3E-34 T 13-10-2018 IPR000160 GGDEF domain CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 Pfam PF00990 Diguanylate cyclase, GGDEF domain 366 518 9.6E-40 T 13-10-2018 IPR000160 GGDEF domain CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 Gene3D G3DSA:3.30.450.20 75 204 1.8E-40 T 13-10-2018 CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 Gene3D G3DSA:3.30.450.20 208 297 3.3E-11 T 13-10-2018 CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 SUPERFAMILY SSF55073 370 518 1.96E-37 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0669 14459e29259541c2f18696a96f20e7ab 530 SUPERFAMILY SSF103190 41 205 7.3E-42 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_1989 10ccd4b7d396737dd2b2383c4c335d10 396 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 6 389 1.2E-195 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1989 10ccd4b7d396737dd2b2383c4c335d10 396 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 80 94 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1989 10ccd4b7d396737dd2b2383c4c335d10 396 Gene3D G3DSA:3.40.50.1100 9 205 6.9E-185 T 13-10-2018 CLOST_1989 10ccd4b7d396737dd2b2383c4c335d10 396 SUPERFAMILY SSF53686 5 386 2.23E-141 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_1989 10ccd4b7d396737dd2b2383c4c335d10 396 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 390 50.994 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1989 10ccd4b7d396737dd2b2383c4c335d10 396 Gene3D G3DSA:3.40.50.1100 53 382 6.9E-185 T 13-10-2018 CLOST_1989 10ccd4b7d396737dd2b2383c4c335d10 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 377 9.0E-43 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_1989 10ccd4b7d396737dd2b2383c4c335d10 396 PIRSF PIRSF001413 2 396 1.9E-172 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1065 451899af756148039c5bae6a08dc6c36 361 Pfam PF00534 Glycosyl transferases group 1 220 333 2.2E-18 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 CLOST_1065 451899af756148039c5bae6a08dc6c36 361 SUPERFAMILY SSF53756 5 334 4.5E-41 T 13-10-2018 CLOST_1065 451899af756148039c5bae6a08dc6c36 361 Gene3D G3DSA:3.40.50.2000 215 351 6.2E-23 T 13-10-2018 CLOST_1065 451899af756148039c5bae6a08dc6c36 361 Gene3D G3DSA:3.40.50.2000 1 214 4.5E-14 T 13-10-2018 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 Gene3D G3DSA:1.10.150.20 72 176 9.9E-19 T 13-10-2018 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 SUPERFAMILY SSF47789 5 64 5.76E-12 T 13-10-2018 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 Pfam PF04545 Sigma-70, region 4 301 344 2.0E-10 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 SUPERFAMILY SSF47789 92 151 1.44E-13 T 13-10-2018 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 Gene3D G3DSA:1.10.150.20 4 66 6.1E-14 T 13-10-2018 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 98 155 3.0E-7 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 10 63 2.0E-4 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 88 147 5.8E-21 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 8 58 1.1E-12 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 Gene3D G3DSA:1.10.10.10 295 351 2.2E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 SUPERFAMILY SSF88659 297 346 9.48E-13 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_1639 5d99f32d612caf751230ddb8b4268b66 911 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 318 344 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_2063 60676f4b623a79eee76a2f28009a4a81 276 Gene3D G3DSA:1.10.10.10 212 274 3.2E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2063 60676f4b623a79eee76a2f28009a4a81 276 Pfam PF00575 S1 RNA binding domain 141 204 2.0E-5 T 13-10-2018 IPR003029 S1 domain GO:0003676 CLOST_2063 60676f4b623a79eee76a2f28009a4a81 276 Gene3D G3DSA:2.40.50.140 143 209 9.2E-13 T 13-10-2018 CLOST_2063 60676f4b623a79eee76a2f28009a4a81 276 SMART SM00316 141 204 5.0E-11 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_2063 60676f4b623a79eee76a2f28009a4a81 276 PIRSF PIRSF012524 1 275 1.4E-65 T 13-10-2018 IPR014464 Conserved virulence factor B CLOST_2063 60676f4b623a79eee76a2f28009a4a81 276 SUPERFAMILY SSF50249 139 205 1.57E-11 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2063 60676f4b623a79eee76a2f28009a4a81 276 Pfam PF13509 S1 domain 69 128 1.1E-9 T 13-10-2018 IPR039566 Conserved virulence factor B, S1 domain CLOST_2063 60676f4b623a79eee76a2f28009a4a81 276 Pfam PF13509 S1 domain 4 62 6.4E-22 T 13-10-2018 IPR039566 Conserved virulence factor B, S1 domain CLOST_0043 6f5f0a5c20fb9c16fd95f777af5697c7 143 Pfam PF02675 S-adenosylmethionine decarboxylase 9 115 5.7E-39 T 13-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CLOST_0043 6f5f0a5c20fb9c16fd95f777af5697c7 143 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 5 115 2.3E-44 T 13-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CLOST_0043 6f5f0a5c20fb9c16fd95f777af5697c7 143 Gene3D G3DSA:3.30.160.750 65 128 2.0E-22 T 13-10-2018 CLOST_0043 6f5f0a5c20fb9c16fd95f777af5697c7 143 SUPERFAMILY SSF56276 5 118 1.84E-41 T 13-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CLOST_0043 6f5f0a5c20fb9c16fd95f777af5697c7 143 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 3 119 30.956 T 13-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CLOST_0043 6f5f0a5c20fb9c16fd95f777af5697c7 143 Gene3D G3DSA:3.30.360.110 3 64 1.7E-26 T 13-10-2018 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 Pfam PF00013 KH domain 210 263 2.2E-6 T 13-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 TIGRFAM TIGR00277 HDIG: HDIG domain 329 406 1.7E-22 T 13-10-2018 IPR006675 HDIG domain CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 12 517 7.9E-239 T 13-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 SMART SM00471 329 435 2.5E-12 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 Gene3D G3DSA:3.30.1370.10 205 308 1.0E-8 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 SUPERFAMILY SSF109604 313 464 1.76E-29 T 13-10-2018 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 Pfam PF01966 HD domain 334 425 1.0E-17 T 13-10-2018 IPR006674 HD domain CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 Hamap MF_00335 Ribonuclease Y [rny]. 9 517 25.44 T 13-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 Gene3D G3DSA:1.10.3210.10 315 469 4.1E-20 T 13-10-2018 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 SUPERFAMILY SSF54791 205 301 2.09E-17 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 SMART SM00322 205 272 3.2E-8 T 13-10-2018 IPR004087 K Homology domain GO:0003676 CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 Pfam PF12072 Domain of unknown function (DUF3552) 11 202 2.9E-60 T 13-10-2018 IPR022711 Ribonuclease Y, N-terminal CLOST_1678 4243dcc907b827b6225ecf50bc109106 517 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 61 206 0.006 T 13-10-2018 CLOST_1337 5741bd40daf547df8b6a54cab178131d 225 SUPERFAMILY SSF53448 1 219 6.93E-35 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_1337 5741bd40daf547df8b6a54cab178131d 225 Pfam PF00535 Glycosyl transferase family 2 5 158 1.2E-23 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CLOST_1337 5741bd40daf547df8b6a54cab178131d 225 Gene3D G3DSA:3.90.550.10 1 225 1.7E-41 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_1485 735ba571a61dc312f123d7d90554cce0 144 SUPERFAMILY SSF46785 7 140 4.68E-38 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1485 735ba571a61dc312f123d7d90554cce0 144 Gene3D G3DSA:3.30.1490.190 92 144 2.6E-20 T 13-10-2018 CLOST_1485 735ba571a61dc312f123d7d90554cce0 144 Gene3D G3DSA:1.10.10.10 1 87 4.6E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1485 735ba571a61dc312f123d7d90554cce0 144 Pfam PF01475 Ferric uptake regulator family 14 137 2.9E-37 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CLOST_1584 9b6477dd1491040d065cfbf0674f07e7 352 Gene3D G3DSA:3.80.30.20 2 251 8.1E-27 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1584 9b6477dd1491040d065cfbf0674f07e7 352 Pfam PF16199 Radical_SAM C-terminal domain 184 270 3.8E-21 T 13-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CLOST_1584 9b6477dd1491040d065cfbf0674f07e7 352 SUPERFAMILY SSF102114 8 261 1.83E-48 T 13-10-2018 CLOST_1584 9b6477dd1491040d065cfbf0674f07e7 352 SMART SM00729 5 223 7.4E-31 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1584 9b6477dd1491040d065cfbf0674f07e7 352 Pfam PF04055 Radical SAM superfamily 11 177 1.0E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 SUPERFAMILY SSF53738 161 259 9.81E-30 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 SUPERFAMILY SSF53738 261 367 2.04E-30 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 257 4.7E-19 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 371 6.7E-33 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 SUPERFAMILY SSF53738 2 183 3.65E-46 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Gene3D G3DSA:3.40.120.10 3 158 1.1E-49 T 13-10-2018 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Gene3D G3DSA:3.30.310.50 374 452 9.2E-26 T 13-10-2018 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 177 196 2.8E-14 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 2.8E-14 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 97 111 2.8E-14 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Gene3D G3DSA:3.40.120.10 260 343 6.4E-70 T 13-10-2018 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 SUPERFAMILY SSF55957 362 448 1.7E-19 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 377 447 5.8E-15 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Gene3D G3DSA:3.40.120.10 177 366 6.4E-70 T 13-10-2018 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 137 4.9E-40 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 448 1.0E-171 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_0497 a78a1e927475f732b03df7018bfaf047 452 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 450 43.462 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CLOST_1173 57ec17cabc10d3fc721a48b65e5ce94a 643 SUPERFAMILY SSF54292 3 89 7.64E-18 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 CLOST_1173 57ec17cabc10d3fc721a48b65e5ce94a 643 Pfam PF14574 Domain of unknown function (DUF4445) 213 625 2.8E-142 T 13-10-2018 IPR027980 Protein of unknown function DUF4445 CLOST_1173 57ec17cabc10d3fc721a48b65e5ce94a 643 Gene3D G3DSA:3.10.20.30 2 92 2.0E-21 T 13-10-2018 IPR012675 Beta-grasp domain superfamily CLOST_1173 57ec17cabc10d3fc721a48b65e5ce94a 643 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 79 7.2E-10 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CLOST_1173 57ec17cabc10d3fc721a48b65e5ce94a 643 Gene3D G3DSA:2.40.50.570 124 209 4.1E-11 T 13-10-2018 CLOST_1173 57ec17cabc10d3fc721a48b65e5ce94a 643 SUPERFAMILY SSF53067 215 554 6.26E-6 T 13-10-2018 CLOST_1173 57ec17cabc10d3fc721a48b65e5ce94a 643 Gene3D G3DSA:3.30.420.480 211 386 2.0E-55 T 13-10-2018 CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 SUPERFAMILY SSF46785 24 113 1.43E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 SMART SM00418 36 114 4.3E-29 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 59 77 - T 13-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 Pfam PF01022 Bacterial regulatory protein, arsR family 43 89 6.8E-19 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 Gene3D G3DSA:1.10.10.10 3 119 6.5E-40 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 85 100 3.6E-20 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 3.6E-20 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 68 3.6E-20 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0568 a6ee407f671dc8c56a7f3ade95e33199 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 3.6E-20 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_2070 56f4a0b141100502d88d2be83196d050 281 Gene3D G3DSA:1.20.1080.10 2 264 3.9E-92 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CLOST_2070 56f4a0b141100502d88d2be83196d050 281 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 22 275 2.9E-76 T 13-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 CLOST_2070 56f4a0b141100502d88d2be83196d050 281 Pfam PF01226 Formate/nitrite transporter 10 272 6.4E-79 T 13-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 CLOST_2070 56f4a0b141100502d88d2be83196d050 281 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 81 90 - T 13-10-2018 IPR024002 Formate/nitrite transporter, conserved site CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 Gene3D G3DSA:3.90.226.10 7 262 7.6E-86 T 13-10-2018 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 260 38.614 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 2 261 4.7E-113 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 142 160 7.0E-38 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 208 219 7.0E-38 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 108 122 7.0E-38 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 230 239 7.0E-38 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 179 196 7.0E-38 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 Pfam PF01039 Carboxyl transferase domain 42 218 2.1E-17 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 CLOST_0891 a95eaa81e2c5f04fb690e4c96852e905 264 SUPERFAMILY SSF52096 7 258 4.62E-78 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_2434 8605ff6c2eb7df9cecc3ee067e42b9c8 523 SUPERFAMILY SSF109604 346 516 1.66E-37 T 13-10-2018 CLOST_2434 8605ff6c2eb7df9cecc3ee067e42b9c8 523 Gene3D G3DSA:1.10.3210.10 329 523 3.0E-70 T 13-10-2018 CLOST_2434 8605ff6c2eb7df9cecc3ee067e42b9c8 523 Gene3D G3DSA:3.40.50.2300 24 176 6.5E-12 T 13-10-2018 CLOST_2434 8605ff6c2eb7df9cecc3ee067e42b9c8 523 Pfam PF11849 Domain of unknown function (DUF3369) 157 331 1.6E-39 T 13-10-2018 IPR021800 Domain of unknown function DUF3369 CLOST_2434 8605ff6c2eb7df9cecc3ee067e42b9c8 523 Pfam PF01966 HD domain 356 477 3.5E-18 T 13-10-2018 IPR006674 HD domain CLOST_2434 8605ff6c2eb7df9cecc3ee067e42b9c8 523 SMART SM00471 349 486 2.9E-7 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_2434 8605ff6c2eb7df9cecc3ee067e42b9c8 523 SUPERFAMILY SSF52172 34 177 1.24E-10 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 PRINTS PR00834 HtrA/DegQ protease family signature 168 192 5.6E-36 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 PRINTS PR00834 HtrA/DegQ protease family signature 128 148 5.6E-36 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 PRINTS PR00834 HtrA/DegQ protease family signature 207 224 5.6E-36 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 5.6E-36 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 PRINTS PR00834 HtrA/DegQ protease family signature 105 117 5.6E-36 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 PRINTS PR00834 HtrA/DegQ protease family signature 313 325 5.6E-36 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 SUPERFAMILY SSF50156 253 363 9.07E-24 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 SUPERFAMILY SSF50494 61 267 2.16E-59 T 13-10-2018 IPR009003 Peptidase S1, PA clan CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 SMART SM00228 272 355 1.6E-13 T 13-10-2018 IPR001478 PDZ domain GO:0005515 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 Gene3D G3DSA:2.40.10.120 53 268 4.8E-70 T 13-10-2018 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 Pfam PF13180 PDZ domain 273 363 2.5E-18 T 13-10-2018 IPR001478 PDZ domain GO:0005515 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 Pfam PF13365 Trypsin-like peptidase domain 96 236 1.7E-35 T 13-10-2018 CLOST_2551 705a9a2661fbcb4715b395b4fa282fd6 364 Gene3D G3DSA:2.30.42.10 270 364 9.1E-23 T 13-10-2018 CLOST_1956 b78f7af803a11f28185f7a02c685adf3 310 SUPERFAMILY SSF143865 12 245 1.44E-50 T 13-10-2018 CLOST_1956 b78f7af803a11f28185f7a02c685adf3 310 Pfam PF01544 CorA-like Mg2+ transporter protein 21 307 1.9E-60 T 13-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CLOST_1956 b78f7af803a11f28185f7a02c685adf3 310 Gene3D G3DSA:1.20.58.340 132 252 8.3E-27 T 13-10-2018 CLOST_1956 b78f7af803a11f28185f7a02c685adf3 310 Gene3D G3DSA:1.20.58.340 254 309 4.8E-11 T 13-10-2018 CLOST_1956 b78f7af803a11f28185f7a02c685adf3 310 Gene3D G3DSA:3.30.460.20 4 131 4.8E-24 T 13-10-2018 CLOST_1956 b78f7af803a11f28185f7a02c685adf3 310 SUPERFAMILY SSF144083 246 307 3.27E-14 T 13-10-2018 CLOST_2062 0eadfeed7fa5a3638ce64c4e4a9e435f 150 SUPERFAMILY SSF54631 1 146 2.65E-42 T 13-10-2018 CLOST_2062 0eadfeed7fa5a3638ce64c4e4a9e435f 150 Gene3D G3DSA:3.10.580.10 1 149 5.2E-44 T 13-10-2018 CLOST_2062 0eadfeed7fa5a3638ce64c4e4a9e435f 150 SMART SM00116 100 147 1.7E-13 T 13-10-2018 IPR000644 CBS domain CLOST_2062 0eadfeed7fa5a3638ce64c4e4a9e435f 150 SMART SM00116 10 58 4.4E-10 T 13-10-2018 IPR000644 CBS domain CLOST_2062 0eadfeed7fa5a3638ce64c4e4a9e435f 150 PIRSF PIRSF037253 1 69 6.3E-12 T 13-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted CLOST_2062 0eadfeed7fa5a3638ce64c4e4a9e435f 150 PIRSF PIRSF037253 75 149 2.6E-12 T 13-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted CLOST_2062 0eadfeed7fa5a3638ce64c4e4a9e435f 150 Pfam PF00571 CBS domain 93 144 4.7E-17 T 13-10-2018 IPR000644 CBS domain CLOST_2062 0eadfeed7fa5a3638ce64c4e4a9e435f 150 Pfam PF00571 CBS domain 3 54 1.4E-16 T 13-10-2018 IPR000644 CBS domain CLOST_2373 ff73edfc88b1a91434c7209013b47453 289 Gene3D G3DSA:3.90.640.20 190 289 3.8E-39 T 13-10-2018 IPR037126 PdaC/RsiV-like superfamily CLOST_2373 ff73edfc88b1a91434c7209013b47453 289 Gene3D G3DSA:3.30.565.40 75 189 4.6E-27 T 13-10-2018 CLOST_2373 ff73edfc88b1a91434c7209013b47453 289 Pfam PF11738 Protein of unknown function (DUF3298) 194 274 2.6E-19 T 13-10-2018 IPR021729 Domain of unknown function DUF3298 CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 58 134 3.5E-15 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 SMART SM00642 193 560 1.9E-5 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 SUPERFAMILY SSF51011 583 671 1.15E-11 T 13-10-2018 CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 Pfam PF00128 Alpha amylase, catalytic domain 205 294 3.3E-10 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 PIRSF PIRSF000463 1 673 8.8E-174 T 13-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 Gene3D G3DSA:3.20.20.80 17 564 2.9E-238 T 13-10-2018 CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 SUPERFAMILY SSF81296 51 146 5.42E-19 T 13-10-2018 IPR014756 Immunoglobulin E-set CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 584 671 7.0E-12 T 13-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 Gene3D G3DSA:2.60.40.10 53 161 2.9E-238 T 13-10-2018 IPR013783 Immunoglobulin-like fold CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 Gene3D G3DSA:2.60.40.1180 579 673 3.5E-24 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta CLOST_1027 d2375c70b97b4d8bb3e5205ec091734a 673 SUPERFAMILY SSF51445 157 549 2.91E-81 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 SUPERFAMILY SSF161093 269 441 4.05E-51 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 Pfam PF03448 MgtE intracellular N domain 23 124 1.9E-28 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 Pfam PF01769 Divalent cation transporter 312 434 9.8E-32 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 Gene3D G3DSA:1.10.357.20 264 441 7.8E-60 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 Gene3D G3DSA:1.25.60.10 1 121 1.3E-29 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 SMART SM00924 23 126 4.5E-32 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 Pfam PF00571 CBS domain 190 244 4.1E-9 T 13-10-2018 IPR000644 CBS domain CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 Pfam PF00571 CBS domain 126 182 1.3E-7 T 13-10-2018 IPR000644 CBS domain CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 SUPERFAMILY SSF158791 2 123 7.59E-30 T 13-10-2018 CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 SMART SM00116 197 245 1.4E-7 T 13-10-2018 IPR000644 CBS domain CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 SMART SM00116 133 186 120.0 T 13-10-2018 IPR000644 CBS domain CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 SUPERFAMILY SSF54631 126 264 3.03E-33 T 13-10-2018 CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 TIGRFAM TIGR00400 mgtE: magnesium transporter 7 441 1.3E-144 T 13-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CLOST_2368 332b16da659a9d49b4285b64fbc71fed 443 Gene3D G3DSA:3.10.580.10 122 249 9.6E-44 T 13-10-2018 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 SUPERFAMILY SSF53244 315 450 5.19E-34 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 Pfam PF01225 Mur ligase family, catalytic domain 26 87 7.3E-9 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 Pfam PF08245 Mur ligase middle domain 106 292 4.7E-48 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 390 2.5E-17 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 Gene3D G3DSA:3.40.1190.10 82 311 6.7E-64 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 SUPERFAMILY SSF63418 1 96 1.03E-19 T 13-10-2018 IPR035911 MurE/MurF, N-terminal CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 Gene3D G3DSA:3.40.1390.10 23 81 6.5E-19 T 13-10-2018 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 SUPERFAMILY SSF53623 101 312 9.94E-55 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 451 30.865 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 Gene3D G3DSA:3.90.190.20 313 456 1.0E-40 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_1899 2dfee15c1cfbd21e0e0d8e8329330576 457 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 450 1.2E-122 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_1926 a53f5f233dd66697be9586736ca11184 600 SUPERFAMILY SSF52518 340 553 4.91E-24 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1926 a53f5f233dd66697be9586736ca11184 600 Gene3D G3DSA:3.40.50.920 220 310 4.5E-5 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1926 a53f5f233dd66697be9586736ca11184 600 Gene3D G3DSA:3.30.70.20 530 590 1.8E-9 T 13-10-2018 CLOST_1926 a53f5f233dd66697be9586736ca11184 600 Gene3D G3DSA:3.40.50.970 354 528 8.0E-15 T 13-10-2018 CLOST_1926 a53f5f233dd66697be9586736ca11184 600 SUPERFAMILY SSF52922 229 285 1.41E-7 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1926 a53f5f233dd66697be9586736ca11184 600 SUPERFAMILY SSF52518 5 202 4.03E-51 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1926 a53f5f233dd66697be9586736ca11184 600 Pfam PF00037 4Fe-4S binding domain 567 588 3.8E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1926 a53f5f233dd66697be9586736ca11184 600 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 368 514 2.3E-18 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CLOST_1926 a53f5f233dd66697be9586736ca11184 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 572 583 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1926 a53f5f233dd66697be9586736ca11184 600 PIRSF PIRSF006439 1 594 1.3E-217 T 13-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CLOST_1926 a53f5f233dd66697be9586736ca11184 600 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 192 8.0E-13 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CLOST_1926 a53f5f233dd66697be9586736ca11184 600 Gene3D G3DSA:3.40.50.970 2 182 1.3E-48 T 13-10-2018 CLOST_2225 3339752c80aa72cf093588ece9fc31e1 308 Pfam PF00892 EamA-like transporter family 155 290 1.5E-14 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_2225 3339752c80aa72cf093588ece9fc31e1 308 Pfam PF00892 EamA-like transporter family 11 145 4.5E-22 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_2225 3339752c80aa72cf093588ece9fc31e1 308 SUPERFAMILY SSF103481 46 149 1.57E-18 T 13-10-2018 CLOST_2225 3339752c80aa72cf093588ece9fc31e1 308 SUPERFAMILY SSF103481 201 294 2.09E-11 T 13-10-2018 CLOST_0792 77b2570046bac350b166ec42f15bc8c6 424 Pfam PF00583 Acetyltransferase (GNAT) family 315 413 5.6E-8 T 13-10-2018 IPR000182 GNAT domain CLOST_0792 77b2570046bac350b166ec42f15bc8c6 424 Gene3D G3DSA:3.40.630.30 285 421 8.8E-18 T 13-10-2018 CLOST_0792 77b2570046bac350b166ec42f15bc8c6 424 SUPERFAMILY SSF55729 295 422 2.38E-16 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0792 77b2570046bac350b166ec42f15bc8c6 424 Gene3D G3DSA:3.40.50.1100 37 134 7.5E-14 T 13-10-2018 CLOST_0792 77b2570046bac350b166ec42f15bc8c6 424 SUPERFAMILY SSF53686 3 285 4.9E-14 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_0792 77b2570046bac350b166ec42f15bc8c6 424 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 268 1.4E-14 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_0792 77b2570046bac350b166ec42f15bc8c6 424 Gene3D G3DSA:3.40.50.1100 4 267 7.5E-14 T 13-10-2018 CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 Pfam PF02272 DHHA1 domain 276 390 2.7E-6 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 SUPERFAMILY SSF55186 102 243 6.67E-32 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 Gene3D G3DSA:3.10.310.40 303 400 2.8E-5 T 13-10-2018 CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 SMART SM00863 197 239 4.0E-14 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 Gene3D G3DSA:3.30.980.10 102 256 1.1E-42 T 13-10-2018 CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 SUPERFAMILY SSF50447 17 98 7.77E-17 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 Pfam PF01411 tRNA synthetases class II (A) 32 102 4.4E-9 T 13-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 197 238 1.6E-11 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CLOST_2025 780fd4af04f626447ab1058c0b87d26e 402 Gene3D G3DSA:2.40.30.130 18 101 9.7E-26 T 13-10-2018 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1165 18.538 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Gene3D G3DSA:1.10.150.390 1104 1166 8.8E-30 T 13-10-2018 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Gene3D G3DSA:1.10.274.100 551 634 5.4E-23 T 13-10-2018 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Pfam PF04983 RNA polymerase Rpb1, domain 3 481 638 2.0E-26 T 13-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Gene3D G3DSA:1.10.1790.20 925 1102 5.1E-71 T 13-10-2018 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Gene3D G3DSA:1.10.132.30 635 769 2.8E-57 T 13-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Gene3D G3DSA:1.10.40.90 366 408 1.5E-24 T 13-10-2018 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Pfam PF05000 RNA polymerase Rpb1, domain 4 668 729 2.4E-12 T 13-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Pfam PF04998 RNA polymerase Rpb1, domain 5 745 1103 4.4E-67 T 13-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 334 1.0E-92 T 13-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Pfam PF00623 RNA polymerase Rpb1, domain 2 385 477 6.2E-28 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Pfam PF00623 RNA polymerase Rpb1, domain 2 336 387 9.8E-9 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Gene3D G3DSA:2.40.50.100 941 1003 5.1E-71 T 13-10-2018 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1155 0.0 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 Gene3D G3DSA:1.10.274.100 482 550 2.7E-25 T 13-10-2018 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 SMART SM00663 227 506 2.5E-183 T 13-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2210 18bfd99abf3d8dd41c6413ae4e577d7d 1179 SUPERFAMILY SSF64484 5 1157 0.0 T 13-10-2018 CLOST_0886 fb5620ad09fe53af5bcd9be3c7ea30e1 376 SUPERFAMILY SSF52172 3 123 8.11E-27 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0886 fb5620ad09fe53af5bcd9be3c7ea30e1 376 SUPERFAMILY SSF109604 136 370 1.16E-16 T 13-10-2018 CLOST_0886 fb5620ad09fe53af5bcd9be3c7ea30e1 376 Gene3D G3DSA:3.40.50.2300 5 123 4.7E-26 T 13-10-2018 CLOST_0886 fb5620ad09fe53af5bcd9be3c7ea30e1 376 Pfam PF00072 Response regulator receiver domain 7 117 1.7E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0886 fb5620ad09fe53af5bcd9be3c7ea30e1 376 Gene3D G3DSA:1.10.3210.10 134 376 1.4E-18 T 13-10-2018 CLOST_0886 fb5620ad09fe53af5bcd9be3c7ea30e1 376 SMART SM00448 5 117 4.2E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Pfam PF00990 Diguanylate cyclase, GGDEF domain 511 654 3.0E-28 T 13-10-2018 IPR000160 GGDEF domain CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 TIGRFAM TIGR00277 HDIG: HDIG domain 682 770 1.1E-8 T 13-10-2018 IPR006675 HDIG domain CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Pfam PF01966 HD domain 683 802 2.8E-21 T 13-10-2018 IPR006674 HD domain CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Gene3D G3DSA:3.30.450.20 400 497 3.7E-13 T 13-10-2018 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Gene3D G3DSA:3.30.70.270 498 664 4.5E-35 T 13-10-2018 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 SUPERFAMILY SSF103190 48 174 8.63E-19 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 SMART SM00267 499 668 6.5E-23 T 13-10-2018 IPR000160 GGDEF domain CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 SMART SM00471 676 811 2.1E-13 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Pfam PF08448 PAS fold 399 500 1.3E-7 T 13-10-2018 IPR013656 PAS fold-4 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 SUPERFAMILY SSF55073 515 654 5.49E-31 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 SUPERFAMILY SSF55785 381 497 1.47E-12 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 387 504 4.6E-10 T 13-10-2018 IPR000014 PAS domain CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Pfam PF02743 Cache domain 26 251 1.4E-29 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 SUPERFAMILY SSF109604 655 842 4.11E-39 T 13-10-2018 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Gene3D G3DSA:1.10.3210.10 665 844 1.9E-66 T 13-10-2018 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Gene3D G3DSA:3.30.450.20 53 165 2.3E-40 T 13-10-2018 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 Gene3D G3DSA:3.30.450.20 41 252 2.3E-40 T 13-10-2018 CLOST_0123 c0b6a88d04e6b16373b47067b9cb3aa2 844 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 508 656 3.0E-27 T 13-10-2018 IPR000160 GGDEF domain CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 Gene3D G3DSA:3.40.50.170 1 207 1.2E-81 T 13-10-2018 CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 3 305 36.584 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 Pfam PF00551 Formyl transferase 5 180 5.7E-47 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 SUPERFAMILY SSF53328 3 207 4.19E-70 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 Gene3D G3DSA:3.10.25.10 208 313 5.8E-30 T 13-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 Pfam PF02911 Formyl transferase, C-terminal domain 206 301 2.5E-24 T 13-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 306 1.5E-96 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CLOST_1855 2aee077a11309d1a0121a1c443dc5f9c 313 SUPERFAMILY SSF50486 206 309 1.57E-27 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 SUPERFAMILY SSF55073 354 508 3.14E-43 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 Pfam PF00990 Diguanylate cyclase, GGDEF domain 350 504 8.3E-41 T 13-10-2018 IPR000160 GGDEF domain CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 Gene3D G3DSA:3.30.70.270 344 522 9.7E-50 T 13-10-2018 CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 Pfam PF00563 EAL domain 533 760 3.3E-68 T 13-10-2018 IPR001633 EAL domain CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 345 505 1.9E-37 T 13-10-2018 IPR000160 GGDEF domain CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 SMART SM00052 515 765 7.8E-102 T 13-10-2018 IPR001633 EAL domain CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 Gene3D G3DSA:3.20.20.450 523 772 1.3E-88 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 SMART SM00267 338 508 7.5E-47 T 13-10-2018 IPR000160 GGDEF domain CLOST_0831 f6199d7fd08420a32f5b2c758fe1b001 779 SUPERFAMILY SSF141868 529 768 2.88E-80 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_1577 54bd81bad8ae04b9de2b7bcc755f12a1 168 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 166 24.497 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CLOST_1577 54bd81bad8ae04b9de2b7bcc755f12a1 168 SUPERFAMILY SSF50346 98 166 8.04E-18 T 13-10-2018 IPR011033 PRC-barrel-like superfamily CLOST_1577 54bd81bad8ae04b9de2b7bcc755f12a1 168 Pfam PF01782 RimM N-terminal domain 8 86 1.4E-22 T 13-10-2018 IPR002676 RimM, N-terminal GO:0006364 CLOST_1577 54bd81bad8ae04b9de2b7bcc755f12a1 168 SUPERFAMILY SSF50447 5 87 3.88E-20 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_1577 54bd81bad8ae04b9de2b7bcc755f12a1 168 Pfam PF05239 PRC-barrel domain 93 166 1.8E-12 T 13-10-2018 IPR027275 PRC-barrel domain CLOST_1577 54bd81bad8ae04b9de2b7bcc755f12a1 168 Gene3D G3DSA:2.40.30.60 5 88 1.2E-22 T 13-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 CLOST_1577 54bd81bad8ae04b9de2b7bcc755f12a1 168 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 6 165 2.1E-45 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CLOST_1577 54bd81bad8ae04b9de2b7bcc755f12a1 168 Gene3D G3DSA:2.30.30.240 91 168 3.2E-15 T 13-10-2018 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 Gene3D G3DSA:3.90.930.12 1 83 3.2E-31 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 39.665 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 Pfam PF00347 Ribosomal protein L6 91 165 2.6E-19 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 Pfam PF00347 Ribosomal protein L6 11 83 7.6E-23 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 Gene3D G3DSA:3.90.930.12 84 180 3.0E-42 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 SUPERFAMILY SSF56053 84 178 6.24E-38 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 PRINTS PR00059 Ribosomal protein L6 signature 100 116 6.1E-34 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 PRINTS PR00059 Ribosomal protein L6 signature 142 163 6.1E-34 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 PRINTS PR00059 Ribosomal protein L6 signature 72 97 6.1E-34 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 PIRSF PIRSF002162 1 178 4.1E-50 T 13-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 SUPERFAMILY SSF56053 1 83 5.14E-26 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 13-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2183 d35194d2047612c299c5b72763626e8d 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 2.8E-77 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 SUPERFAMILY SSF158472 367 418 2.75E-5 T 13-10-2018 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 631 645 6.6E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 687 700 6.6E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 649 659 6.6E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 662 680 6.6E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 SMART SM00304 365 419 0.008 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 Gene3D G3DSA:3.30.565.10 548 701 6.8E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 Gene3D G3DSA:3.30.450.20 140 220 1.9E-14 T 13-10-2018 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 593 700 1.1E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 Gene3D G3DSA:1.20.1480.50 333 426 1.3E-7 T 13-10-2018 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 Gene3D G3DSA:3.30.450.20 221 332 1.9E-14 T 13-10-2018 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 SUPERFAMILY SSF47384 460 497 1.47E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 SMART SM00387 591 701 3.3E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 SUPERFAMILY SSF55874 553 699 1.27E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 Pfam PF02743 Cache domain 39 328 1.9E-21 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_2435 b999f08c26c67a0642e61c43d4f24b0a 701 Gene3D G3DSA:1.10.287.130 443 543 6.2E-16 T 13-10-2018 CLOST_0430 f34ec40cd3ac016d53140610ddeef9bf 394 Gene3D G3DSA:3.40.640.10 69 300 1.3E-134 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0430 f34ec40cd3ac016d53140610ddeef9bf 394 Gene3D G3DSA:3.90.1150.10 15 377 1.3E-134 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0430 f34ec40cd3ac016d53140610ddeef9bf 394 Pfam PF00155 Aminotransferase class I and II 34 378 2.2E-50 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_0430 f34ec40cd3ac016d53140610ddeef9bf 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CLOST_0430 f34ec40cd3ac016d53140610ddeef9bf 394 SUPERFAMILY SSF53383 14 389 1.05E-86 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0852 e1a82c35194284bb66455ef426017a59 721 Gene3D G3DSA:3.10.620.30 380 548 1.2E-26 T 13-10-2018 CLOST_0852 e1a82c35194284bb66455ef426017a59 721 SUPERFAMILY SSF54001 361 545 2.1E-38 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_0852 e1a82c35194284bb66455ef426017a59 721 Pfam PF01841 Transglutaminase-like superfamily 418 534 1.8E-26 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0852 e1a82c35194284bb66455ef426017a59 721 SMART SM00460 465 536 3.8E-19 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 469 602 9.3E-36 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 SUPERFAMILY SSF58104 337 673 9.42E-60 T 13-10-2018 CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 Gene3D G3DSA:3.30.450.20 76 187 6.4E-23 T 13-10-2018 CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 Gene3D G3DSA:3.30.450.20 66 287 6.4E-23 T 13-10-2018 CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 Pfam PF00672 HAMP domain 318 363 4.8E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 SMART SM00304 317 369 4.4E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 SMART SM00283 384 673 4.0E-44 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 Gene3D G3DSA:1.10.287.950 316 674 1.2E-62 T 13-10-2018 CLOST_0961 f2610fa44fe7364ed731fd848f3fd5f4 674 Pfam PF02743 Cache domain 48 279 7.7E-19 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 SMART SM00245 179 365 4.8E-59 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 Gene3D G3DSA:3.90.226.10 194 362 2.3E-89 T 13-10-2018 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 SMART SM00228 106 178 2.6E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 Gene3D G3DSA:3.30.750.44 57 340 2.3E-89 T 13-10-2018 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 63 372 1.6E-97 T 13-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 Pfam PF13180 PDZ domain 108 179 2.8E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 Gene3D G3DSA:2.30.42.10 106 193 2.3E-89 T 13-10-2018 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 SUPERFAMILY SSF52096 52 373 5.47E-71 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 SUPERFAMILY SSF50156 81 201 1.04E-17 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 CLOST_2082 99c8119aa9577817e53b30a5579054f9 388 Pfam PF03572 Peptidase family S41 204 363 1.1E-52 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CLOST_0241 61ce363deb65f29e97227b7914330569 474 Gene3D G3DSA:1.20.1480.50 163 252 1.5E-12 T 13-10-2018 CLOST_0241 61ce363deb65f29e97227b7914330569 474 Gene3D G3DSA:1.10.287.130 253 317 3.1E-20 T 13-10-2018 CLOST_0241 61ce363deb65f29e97227b7914330569 474 SMART SM00387 365 473 1.7E-31 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0241 61ce363deb65f29e97227b7914330569 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 1.5E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0241 61ce363deb65f29e97227b7914330569 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 470 1.5E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0241 61ce363deb65f29e97227b7914330569 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 1.5E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0241 61ce363deb65f29e97227b7914330569 474 SUPERFAMILY SSF55874 311 471 8.91E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0241 61ce363deb65f29e97227b7914330569 474 SMART SM00304 200 252 7.4E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0241 61ce363deb65f29e97227b7914330569 474 SUPERFAMILY SSF158472 201 248 1.7E-8 T 13-10-2018 CLOST_0241 61ce363deb65f29e97227b7914330569 474 Pfam PF00672 HAMP domain 201 247 5.3E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0241 61ce363deb65f29e97227b7914330569 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 471 1.2E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0241 61ce363deb65f29e97227b7914330569 474 SMART SM00388 253 321 3.2E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_0241 61ce363deb65f29e97227b7914330569 474 SUPERFAMILY SSF47384 236 322 2.75E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_0241 61ce363deb65f29e97227b7914330569 474 Gene3D G3DSA:3.30.565.10 318 472 7.1E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0241 61ce363deb65f29e97227b7914330569 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 320 7.5E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_0112 e4ce3d5bf34aca137e3de004e39e8d46 108 Pfam PF01638 HxlR-like helix-turn-helix 19 107 6.2E-35 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type CLOST_0112 e4ce3d5bf34aca137e3de004e39e8d46 108 Gene3D G3DSA:1.10.10.10 1 108 1.2E-42 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0112 e4ce3d5bf34aca137e3de004e39e8d46 108 SUPERFAMILY SSF46785 7 105 5.01E-37 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2019 4e1049eefeeb574d3f3e147de03d0e67 119 SUPERFAMILY SSF53146 1 114 8.37E-34 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CLOST_2019 4e1049eefeeb574d3f3e147de03d0e67 119 Gene3D G3DSA:3.30.420.130 1 104 4.2E-30 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CLOST_2019 4e1049eefeeb574d3f3e147de03d0e67 119 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 96 1.4E-22 T 13-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 Gene3D G3DSA:2.40.30.170 75 84 5.2E-12 T 13-10-2018 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 Gene3D G3DSA:1.10.287.470 152 217 3.6E-6 T 13-10-2018 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 SUPERFAMILY SSF111369 76 170 2.88E-8 T 13-10-2018 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 Gene3D G3DSA:2.40.30.170 288 379 1.3E-33 T 13-10-2018 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 SUPERFAMILY SSF111369 177 313 2.48E-5 T 13-10-2018 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 Gene3D G3DSA:1.10.287.470 119 142 5.2E-12 T 13-10-2018 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 Gene3D G3DSA:2.40.420.20 380 448 1.3E-33 T 13-10-2018 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 338 4.6E-11 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 Gene3D G3DSA:2.40.50.100 239 287 1.3E-33 T 13-10-2018 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 232 448 5.1E-28 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CLOST_0451 b9ec89bc8072ad284a5b6903346ecc25 461 Gene3D G3DSA:2.40.50.100 85 118 5.2E-12 T 13-10-2018 CLOST_0050 65285875167e9e51fda526ad84969d3b 200 Pfam PF02915 Rubrerythrin 14 147 3.4E-27 T 13-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CLOST_0050 65285875167e9e51fda526ad84969d3b 200 Gene3D G3DSA:1.20.1260.10 3 155 1.7E-49 T 13-10-2018 IPR012347 Ferritin-like CLOST_0050 65285875167e9e51fda526ad84969d3b 200 SUPERFAMILY SSF47240 6 154 1.8E-37 T 13-10-2018 IPR009078 Ferritin-like superfamily CLOST_0050 65285875167e9e51fda526ad84969d3b 200 Gene3D G3DSA:2.20.28.10 156 200 4.3E-14 T 13-10-2018 CLOST_0050 65285875167e9e51fda526ad84969d3b 200 SUPERFAMILY SSF57802 157 197 1.02E-9 T 13-10-2018 CLOST_1452 d86abbf00a4020af933d8c5f63b8dbdd 92 Pfam PF01817 Chorismate mutase type II 8 84 1.3E-16 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CLOST_1452 d86abbf00a4020af933d8c5f63b8dbdd 92 SUPERFAMILY SSF48600 2 86 2.75E-17 T 13-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CLOST_1452 d86abbf00a4020af933d8c5f63b8dbdd 92 TIGRFAM TIGR01805 CM_mono_grmpos: chorismate mutase 4 84 6.6E-21 T 13-10-2018 IPR011279 Chorismate mutase, Gram-positive CLOST_1452 d86abbf00a4020af933d8c5f63b8dbdd 92 SMART SM00830 8 87 4.4E-16 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CLOST_1452 d86abbf00a4020af933d8c5f63b8dbdd 92 Gene3D G3DSA:1.20.59.10 1 85 6.5E-19 T 13-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CLOST_1631 a5c77f8db204f310753e23f3227db98a 199 SMART SM00903 11 156 7.1E-23 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 CLOST_1631 a5c77f8db204f310753e23f3227db98a 199 SUPERFAMILY SSF50475 10 176 8.83E-46 T 13-10-2018 CLOST_1631 a5c77f8db204f310753e23f3227db98a 199 Gene3D G3DSA:2.30.110.10 2 193 6.9E-67 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 CLOST_1631 a5c77f8db204f310753e23f3227db98a 199 Pfam PF01613 Flavin reductase like domain 14 172 7.4E-28 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 CLOST_1579 208123d45b923669c48bcd435d6a3bee 80 SUPERFAMILY SSF54565 1 79 1.31E-33 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1579 208123d45b923669c48bcd435d6a3bee 80 Pfam PF00886 Ribosomal protein S16 8 66 5.9E-26 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1579 208123d45b923669c48bcd435d6a3bee 80 Gene3D G3DSA:3.30.1320.10 1 80 7.2E-35 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1579 208123d45b923669c48bcd435d6a3bee 80 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 3.3E-35 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1579 208123d45b923669c48bcd435d6a3bee 80 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 76 25.723 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 Gene3D G3DSA:1.10.287.130 182 256 2.0E-12 T 13-10-2018 CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 SUPERFAMILY SSF47384 180 253 1.59E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 299 398 1.3E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 SUPERFAMILY SSF55874 245 396 3.14E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 SMART SM00387 298 407 8.8E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 Pfam PF00512 His Kinase A (phospho-acceptor) domain 194 254 2.7E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 1.9E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 362 1.9E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 SMART SM00388 193 255 1.1E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1601 599022ade6b4ed93a2a1500da525d86c 409 Gene3D G3DSA:3.30.565.10 261 409 8.9E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 ProSitePatterns PS01071 grpE protein signature. 156 197 - T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 SUPERFAMILY SSF58014 54 145 1.12E-24 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 PRINTS PR00773 GrpE protein signature 100 115 6.3E-27 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 PRINTS PR00773 GrpE protein signature 153 168 6.3E-27 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 PRINTS PR00773 GrpE protein signature 72 88 6.3E-27 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 PRINTS PR00773 GrpE protein signature 178 197 6.3E-27 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 Pfam PF01025 GrpE 40 199 1.6E-48 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 Hamap MF_01151 Protein GrpE [grpE]. 16 199 20.744 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 Gene3D G3DSA:3.90.20.20 3 143 4.5E-25 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 Gene3D G3DSA:2.30.22.10 145 199 1.9E-23 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CLOST_1794 65d1da55c08dd36c51b6f69658f8d8e9 199 SUPERFAMILY SSF51064 147 199 9.94E-16 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CLOST_1917 c2299ddde00ec58332cc4e2f28464443 598 Gene3D G3DSA:3.60.40.10 367 597 1.8E-45 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1917 c2299ddde00ec58332cc4e2f28464443 598 Gene3D G3DSA:3.30.450.40 187 333 2.0E-5 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_1917 c2299ddde00ec58332cc4e2f28464443 598 SMART SM00331 368 592 3.8E-20 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1917 c2299ddde00ec58332cc4e2f28464443 598 SUPERFAMILY SSF55781 194 332 2.05E-7 T 13-10-2018 CLOST_1917 c2299ddde00ec58332cc4e2f28464443 598 Gene3D G3DSA:3.30.450.40 7 180 3.7E-11 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_1917 c2299ddde00ec58332cc4e2f28464443 598 SUPERFAMILY SSF55781 80 179 3.93E-10 T 13-10-2018 CLOST_1917 c2299ddde00ec58332cc4e2f28464443 598 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 397 592 1.6E-36 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_0799 1569aa5cc621107148eec7d9df827154 60 Pfam PF08984 Domain of unknown function (DUF1858) 2 55 3.4E-21 T 13-10-2018 IPR015077 Domain of unknown function DUF1858 CLOST_0799 1569aa5cc621107148eec7d9df827154 60 Gene3D G3DSA:1.10.3910.10 1 60 7.3E-24 T 13-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily CLOST_0799 1569aa5cc621107148eec7d9df827154 60 TIGRFAM TIGR03980 prismane_assoc: hybrid cluster protein-associated redox disulfide domain 2 59 5.2E-25 T 13-10-2018 IPR023883 Conserved hypothetical protein CHP03980, redox-disulphide CLOST_0799 1569aa5cc621107148eec7d9df827154 60 SUPERFAMILY SSF140683 1 60 3.53E-18 T 13-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 Gene3D G3DSA:3.40.630.10 9 423 6.0E-154 T 13-10-2018 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 259 277 1.4E-44 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 106 126 1.4E-44 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 143 160 1.4E-44 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 73 89 1.4E-44 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 391 406 1.4E-44 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 302 318 1.4E-44 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 13 424 7.3E-132 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 SUPERFAMILY SSF53187 6 424 2.06E-95 T 13-10-2018 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 SUPERFAMILY SSF101821 87 210 4.21E-34 T 13-10-2018 CLOST_0556 c34db99473eeb24e3222c953dadfaf99 426 Gene3D G3DSA:2.30.250.10 83 214 6.0E-154 T 13-10-2018 IPR023358 Peptidase M18, domain 2 GO:0004177 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Pfam PF00271 Helicase conserved C-terminal domain 214 322 8.7E-22 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Pfam PF00270 DEAD/DEAH box helicase 19 179 7.1E-19 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Pfam PF09382 RQC domain 402 510 4.1E-37 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 SMART SM00956 405 508 1.1E-45 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Gene3D G3DSA:1.10.10.10 400 522 2.7E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 4 599 8.0E-234 T 13-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Gene3D G3DSA:1.10.150.80 526 600 2.1E-24 T 13-10-2018 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 SUPERFAMILY SSF47819 528 599 5.45E-24 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Gene3D G3DSA:3.40.50.300 1 199 1.2E-73 T 13-10-2018 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Pfam PF00570 HRDC domain 532 597 4.1E-21 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 SMART SM00341 527 600 6.7E-12 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 5 456 6.2E-152 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 SMART SM00487 12 209 5.8E-29 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Pfam PF16124 RecQ zinc-binding 335 397 7.8E-15 T 13-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 SMART SM00490 242 323 3.0E-29 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 SUPERFAMILY SSF52540 56 344 1.1E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 Gene3D G3DSA:3.40.50.300 201 399 9.4E-63 T 13-10-2018 CLOST_2507 1c5d67eb565b1c8c53e649e927fd4b3c 600 SUPERFAMILY SSF46785 396 520 2.09E-37 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0536 f5abe517e3c7116f68122eea75776e76 125 SUPERFAMILY SSF55298 1 125 5.65E-46 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 CLOST_0536 f5abe517e3c7116f68122eea75776e76 125 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 13-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 CLOST_0536 f5abe517e3c7116f68122eea75776e76 125 Pfam PF01042 Endoribonuclease L-PSP 9 124 5.6E-42 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 CLOST_0536 f5abe517e3c7116f68122eea75776e76 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 124 1.1E-52 T 13-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 CLOST_0536 f5abe517e3c7116f68122eea75776e76 125 Gene3D G3DSA:3.30.1330.40 1 125 1.7E-52 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 CLOST_2014 b493bc7282e25544f50db64496461aab 360 TIGRFAM TIGR04112 seleno_YedE: putative selenium metabolism protein, YedE family 7 341 7.1E-151 T 13-10-2018 IPR026366 Putative selenium metabolism protein, YedE family CLOST_2014 b493bc7282e25544f50db64496461aab 360 Pfam PF04143 Sulphur transport 4 105 3.5E-8 T 13-10-2018 IPR007272 Sulphur transport domain CLOST_2014 b493bc7282e25544f50db64496461aab 360 Pfam PF04143 Sulphur transport 206 317 1.9E-12 T 13-10-2018 IPR007272 Sulphur transport domain CLOST_0900 7a1dc5d57c5845281e0955f41dc4d332 140 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 139 1.3E-52 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CLOST_0900 7a1dc5d57c5845281e0955f41dc4d332 140 Pfam PF07977 FabA-like domain 11 134 8.0E-32 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CLOST_0900 7a1dc5d57c5845281e0955f41dc4d332 140 Gene3D G3DSA:3.10.129.10 1 140 5.6E-54 T 13-10-2018 CLOST_0900 7a1dc5d57c5845281e0955f41dc4d332 140 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 140 29.986 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CLOST_0900 7a1dc5d57c5845281e0955f41dc4d332 140 SUPERFAMILY SSF54637 1 139 3.32E-42 T 13-10-2018 IPR029069 HotDog domain superfamily CLOST_1687 1c384b38612b3913f041263257365238 297 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 173 213 8.5E-10 T 13-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CLOST_1687 1c384b38612b3913f041263257365238 297 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 296 18.086 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1687 1c384b38612b3913f041263257365238 297 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 172 3.3E-56 T 13-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CLOST_1687 1c384b38612b3913f041263257365238 297 Gene3D G3DSA:3.30.2350.10 1 236 3.2E-91 T 13-10-2018 CLOST_1687 1c384b38612b3913f041263257365238 297 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 210 9.0E-78 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1687 1c384b38612b3913f041263257365238 297 SUPERFAMILY SSF55120 1 222 1.24E-76 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 Pfam PF04055 Radical SAM superfamily 169 337 6.5E-29 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 Gene3D G3DSA:3.80.30.20 161 394 2.9E-88 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 25 445 7.7E-138 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 28 437 1.7E-141 T 13-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 SUPERFAMILY SSF102114 133 387 1.96E-60 T 13-10-2018 CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 Pfam PF00919 Uncharacterized protein family UPF0004 25 119 7.8E-25 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 167 187 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 Gene3D G3DSA:3.40.50.12160 24 156 1.7E-22 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily CLOST_1789 f9a4c3de5c099aabfa88c0f251dadde4 454 SMART SM00729 163 380 6.6E-58 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0409 efa34789239b3652b10f36495c4d8bbc 287 Pfam PF00483 Nucleotidyl transferase 2 238 3.2E-67 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CLOST_0409 efa34789239b3652b10f36495c4d8bbc 287 SUPERFAMILY SSF53448 1 286 2.93E-87 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0409 efa34789239b3652b10f36495c4d8bbc 287 Gene3D G3DSA:3.90.550.10 1 287 1.4E-84 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0409 efa34789239b3652b10f36495c4d8bbc 287 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 287 1.9E-144 T 13-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CLOST_0331 426108074eeb839711a140841b6faaf7 610 SMART SM00283 318 608 1.4E-11 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0331 426108074eeb839711a140841b6faaf7 610 SMART SM00304 245 303 0.0012 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0331 426108074eeb839711a140841b6faaf7 610 Gene3D G3DSA:1.10.287.950 245 592 9.2E-47 T 13-10-2018 CLOST_0331 426108074eeb839711a140841b6faaf7 610 SUPERFAMILY SSF58104 271 607 8.02E-50 T 13-10-2018 CLOST_0331 426108074eeb839711a140841b6faaf7 610 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 391 508 8.4E-25 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0331 426108074eeb839711a140841b6faaf7 610 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 41 66 1.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0331 426108074eeb839711a140841b6faaf7 610 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 457 1.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0331 426108074eeb839711a140841b6faaf7 610 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 459 488 1.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_1378 450ead9707edf2917eec7820ed8068f5 262 Gene3D G3DSA:3.40.50.280 102 262 9.6E-50 T 13-10-2018 CLOST_1378 450ead9707edf2917eec7820ed8068f5 262 Gene3D G3DSA:3.30.30.60 33 84 9.5E-28 T 13-10-2018 IPR036843 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain superfamily GO:0046983 CLOST_1378 450ead9707edf2917eec7820ed8068f5 262 SUPERFAMILY SSF117778 33 84 2.62E-19 T 13-10-2018 IPR036843 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain superfamily GO:0046983 CLOST_1378 450ead9707edf2917eec7820ed8068f5 262 Pfam PF02310 B12 binding domain 122 245 7.9E-18 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_1378 450ead9707edf2917eec7820ed8068f5 262 SUPERFAMILY SSF52242 105 259 3.3E-43 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_1378 450ead9707edf2917eec7820ed8068f5 262 Pfam PF16554 Dimerisation domain of d-ornithine 4,5-aminomutase 22 97 2.7E-33 T 13-10-2018 IPR028991 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal GO:0046983 CLOST_2527 0126bdd76ba2eacbd64ed5f1ce0080d9 171 Pfam PF07799 Protein of unknown function (DUF1643) 21 157 3.2E-24 T 13-10-2018 IPR012441 Protein of unknown function DUF1643 CLOST_0052 af91648cbe73c90a5ef7ebfa06146e27 483 SMART SM00642 5 391 5.1E-59 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CLOST_0052 af91648cbe73c90a5ef7ebfa06146e27 483 SUPERFAMILY SSF51011 394 480 2.16E-28 T 13-10-2018 CLOST_0052 af91648cbe73c90a5ef7ebfa06146e27 483 Gene3D G3DSA:2.40.30.140 104 207 4.7E-157 T 13-10-2018 CLOST_0052 af91648cbe73c90a5ef7ebfa06146e27 483 Gene3D G3DSA:2.60.40.1180 397 482 1.6E-30 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta CLOST_0052 af91648cbe73c90a5ef7ebfa06146e27 483 SUPERFAMILY SSF51445 5 374 3.33E-100 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily CLOST_0052 af91648cbe73c90a5ef7ebfa06146e27 483 Pfam PF00128 Alpha amylase, catalytic domain 30 375 5.0E-30 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CLOST_0052 af91648cbe73c90a5ef7ebfa06146e27 483 Gene3D G3DSA:3.20.20.80 6 372 4.7E-157 T 13-10-2018 CLOST_0052 af91648cbe73c90a5ef7ebfa06146e27 483 PIRSF PIRSF001021 1 483 1.9E-210 T 13-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 CLOST_1550 8e235d282c1207e9d052700939b28ce8 235 Pfam PF12706 Beta-lactamase superfamily domain 42 198 1.1E-9 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1550 8e235d282c1207e9d052700939b28ce8 235 Gene3D G3DSA:3.60.15.10 6 235 1.5E-23 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1550 8e235d282c1207e9d052700939b28ce8 235 SMART SM00849 11 182 7.3E-9 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1550 8e235d282c1207e9d052700939b28ce8 235 SUPERFAMILY SSF56281 1 213 8.26E-25 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1798 ecc34f63dcc4f81bd251644da7b6376a 156 ProSitePatterns PS00194 Thioredoxin family active site. 68 86 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CLOST_1798 ecc34f63dcc4f81bd251644da7b6376a 156 Pfam PF00085 Thioredoxin 51 152 3.9E-18 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 CLOST_1798 ecc34f63dcc4f81bd251644da7b6376a 156 SUPERFAMILY SSF52833 50 153 2.6E-23 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_1798 ecc34f63dcc4f81bd251644da7b6376a 156 Gene3D G3DSA:3.40.30.10 40 156 1.6E-25 T 13-10-2018 CLOST_1153 753a62b72462fdbd75cc7566f73281e1 601 Pfam PF04055 Radical SAM superfamily 196 358 7.4E-19 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1153 753a62b72462fdbd75cc7566f73281e1 601 Gene3D G3DSA:3.40.50.280 8 136 3.2E-9 T 13-10-2018 CLOST_1153 753a62b72462fdbd75cc7566f73281e1 601 SUPERFAMILY SSF52242 40 132 4.71E-8 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_1153 753a62b72462fdbd75cc7566f73281e1 601 SMART SM00729 191 395 7.1E-30 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1153 753a62b72462fdbd75cc7566f73281e1 601 Pfam PF02310 B12 binding domain 11 122 2.4E-16 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_1153 753a62b72462fdbd75cc7566f73281e1 601 SUPERFAMILY SSF102114 181 411 1.1E-39 T 13-10-2018 CLOST_1153 753a62b72462fdbd75cc7566f73281e1 601 Gene3D G3DSA:3.80.30.20 189 381 8.1E-22 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1153 753a62b72462fdbd75cc7566f73281e1 601 Pfam PF13311 Protein of unknown function (DUF4080) 387 577 1.5E-39 T 13-10-2018 IPR025288 Domain of unknown function DUF4080 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 69 2.7E-19 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 7 875 7.7E-153 T 13-10-2018 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 Pfam PF00702 haloacid dehalogenase-like hydrolase 320 623 2.4E-21 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 Pfam PF00122 E1-E2 ATPase 109 303 6.7E-52 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 Gene3D G3DSA:2.70.150.10 14 227 0.0 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 SUPERFAMILY SSF81653 112 223 9.81E-30 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 SUPERFAMILY SSF81665 2 880 2.35E-140 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 211 346 9.4E-29 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 579 699 6.1E-35 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 176 2.9E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 SUPERFAMILY SSF81660 333 515 3.6E-48 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 Pfam PF00689 Cation transporting ATPase, C-terminus 693 876 5.5E-52 T 13-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 Gene3D G3DSA:3.40.50.1000 321 654 0.0 T 13-10-2018 IPR023214 HAD superfamily CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 666 5.5E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 581 597 5.5E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 468 486 5.5E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 609 625 5.5E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 SUPERFAMILY SSF56784 322 713 1.94E-60 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 Gene3D G3DSA:1.20.1110.10 53 874 0.0 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 Gene3D G3DSA:3.40.1110.10 334 514 0.0 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 SMART SM00831 1 75 2.4E-27 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 2.2E-40 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 518 2.2E-40 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 539 2.2E-40 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 645 2.2E-40 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 2.2E-40 T 13-10-2018 CLOST_1597 274559addfcdf2e8c21e9c16ca76b130 884 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 628 2.2E-40 T 13-10-2018 CLOST_0401 cc42bab38189b9cf784a899b4f550f2a 623 SUPERFAMILY SSF51735 153 279 3.46E-19 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0401 cc42bab38189b9cf784a899b4f550f2a 623 SUPERFAMILY SSF51735 289 552 8.85E-58 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0401 cc42bab38189b9cf784a899b4f550f2a 623 Gene3D G3DSA:3.90.25.30 454 554 4.8E-121 T 13-10-2018 CLOST_0401 cc42bab38189b9cf784a899b4f550f2a 623 Pfam PF13727 CoA-binding domain 67 247 9.8E-12 T 13-10-2018 CLOST_0401 cc42bab38189b9cf784a899b4f550f2a 623 Gene3D G3DSA:3.40.50.720 289 574 4.8E-121 T 13-10-2018 CLOST_0401 cc42bab38189b9cf784a899b4f550f2a 623 Pfam PF02719 Polysaccharide biosynthesis protein 292 574 3.4E-123 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CLOST_0401 cc42bab38189b9cf784a899b4f550f2a 623 Gene3D G3DSA:3.40.50.720 152 273 1.3E-32 T 13-10-2018 CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 Gene3D G3DSA:3.30.465.10 294 376 5.8E-25 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 Pfam PF01595 Domain of unknown function DUF21 2 150 1.9E-44 T 13-10-2018 IPR002550 CNNM, transmembrane domain CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 SMART SM01091 301 377 6.6E-23 T 13-10-2018 IPR005170 Transporter-associated domain CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 Pfam PF03471 Transporter associated domain 302 375 2.8E-22 T 13-10-2018 IPR005170 Transporter-associated domain CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 Gene3D G3DSA:3.10.580.10 145 293 1.4E-50 T 13-10-2018 CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 SUPERFAMILY SSF54631 160 303 1.64E-30 T 13-10-2018 CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 SUPERFAMILY SSF56176 299 376 7.36E-22 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 Pfam PF00571 CBS domain 233 285 0.0018 T 13-10-2018 IPR000644 CBS domain CLOST_1942 f6fff86d18f67e05269cbee62abe9aea 377 Pfam PF00571 CBS domain 165 220 0.0011 T 13-10-2018 IPR000644 CBS domain CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 SUPERFAMILY SSF55008 4 69 3.67E-17 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 792 2.5E-193 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 SUPERFAMILY SSF55008 72 142 5.63E-20 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Gene3D G3DSA:3.30.70.100 2 68 8.4E-18 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Pfam PF00403 Heavy-metal-associated domain 76 134 3.7E-17 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Pfam PF00403 Heavy-metal-associated domain 10 67 1.3E-12 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Gene3D G3DSA:3.40.1110.10 505 621 2.7E-92 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 496 502 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 226 791 7.0E-205 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 265 768 7.2E-96 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Gene3D G3DSA:3.40.50.1000 475 741 2.7E-92 T 13-10-2018 IPR023214 HAD superfamily CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 38 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 ProSitePatterns PS01047 Heavy-metal-associated domain. 77 106 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 689 708 1.2E-26 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 636 646 1.2E-26 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 342 356 1.2E-26 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 712 724 1.2E-26 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 494 508 1.2E-26 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 SUPERFAMILY SSF81665 260 760 3.01E-12 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Pfam PF00702 haloacid dehalogenase-like hydrolase 490 703 1.1E-40 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Gene3D G3DSA:3.30.70.100 69 146 4.0E-20 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 SUPERFAMILY SSF81653 296 392 6.67E-30 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Gene3D G3DSA:2.70.150.20 285 397 1.2E-44 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 PRINTS PR00942 Copper-transporting ATPase 1 signature 5 30 3.3E-17 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 PRINTS PR00942 Copper-transporting ATPase 1 signature 209 234 3.3E-17 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 PRINTS PR00942 Copper-transporting ATPase 1 signature 189 209 3.3E-17 T 13-10-2018 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 73 134 1.5E-13 T 13-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 7 68 2.3E-9 T 13-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 SUPERFAMILY SSF56784 493 789 4.85E-60 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_2050 d780b302f011f8a8d79fe5dd3d637171 796 Pfam PF00122 E1-E2 ATPase 293 473 6.1E-60 T 13-10-2018 CLOST_1560 03c3797fa421899637aeb164725bf22e 68 Gene3D G3DSA:1.10.260.40 4 65 8.5E-13 T 13-10-2018 CLOST_1560 03c3797fa421899637aeb164725bf22e 68 Pfam PF01381 Helix-turn-helix 11 61 1.1E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1560 03c3797fa421899637aeb164725bf22e 68 SMART SM00530 6 61 1.5E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1560 03c3797fa421899637aeb164725bf22e 68 SUPERFAMILY SSF47413 6 61 3.66E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_0399 92b52896d331bca571baea954cd3b3f5 343 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 168 331 1.2E-28 T 13-10-2018 IPR000160 GGDEF domain CLOST_0399 92b52896d331bca571baea954cd3b3f5 343 Gene3D G3DSA:3.30.70.270 166 343 7.1E-41 T 13-10-2018 CLOST_0399 92b52896d331bca571baea954cd3b3f5 343 SUPERFAMILY SSF55073 176 334 3.06E-36 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0399 92b52896d331bca571baea954cd3b3f5 343 SMART SM00267 160 333 5.4E-28 T 13-10-2018 IPR000160 GGDEF domain CLOST_0399 92b52896d331bca571baea954cd3b3f5 343 Pfam PF00990 Diguanylate cyclase, GGDEF domain 174 328 5.5E-32 T 13-10-2018 IPR000160 GGDEF domain CLOST_1864 00e3c619e53e02f2de0b70662c84a3f9 590 Pfam PF05670 Domain of unknown function (DUF814) 472 559 1.6E-30 T 13-10-2018 IPR008532 Domain of unknown function DUF814 CLOST_1864 00e3c619e53e02f2de0b70662c84a3f9 590 Gene3D G3DSA:2.30.310.10 1 168 2.2E-60 T 13-10-2018 CLOST_1864 00e3c619e53e02f2de0b70662c84a3f9 590 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 462 5.9E-144 T 13-10-2018 CLOST_0848 c69324442323371ae5b2ba03d53f59b2 86 Gene3D G3DSA:3.30.70.1150 1 84 4.0E-26 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal CLOST_0848 c69324442323371ae5b2ba03d53f59b2 86 SUPERFAMILY SSF55021 3 80 4.12E-22 T 13-10-2018 CLOST_0848 c69324442323371ae5b2ba03d53f59b2 86 TIGRFAM TIGR03959 hyd_TM1266: putative iron-only hydrogenase system regulator 4 79 8.6E-28 T 13-10-2018 IPR023860 [FeFe]-hydrogenase system regulator TM1266 CLOST_0170 3bdb7c51d639f4db7a402ce55c261e97 193 Gene3D G3DSA:2.40.240.10 2 87 1.0E-20 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_0170 3bdb7c51d639f4db7a402ce55c261e97 193 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 10 172 5.2E-31 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CLOST_0170 3bdb7c51d639f4db7a402ce55c261e97 193 Pfam PF01386 Ribosomal L25p family 8 84 3.8E-16 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CLOST_0170 3bdb7c51d639f4db7a402ce55c261e97 193 Gene3D G3DSA:2.170.120.20 89 181 7.2E-16 T 13-10-2018 IPR037121 Ribosomal protein L25, C-terminal CLOST_0170 3bdb7c51d639f4db7a402ce55c261e97 193 SUPERFAMILY SSF50715 9 175 5.41E-34 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_0170 3bdb7c51d639f4db7a402ce55c261e97 193 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 87 1.0E-7 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CLOST_0170 3bdb7c51d639f4db7a402ce55c261e97 193 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 92 175 1.1E-16 T 13-10-2018 IPR020057 Ribosomal protein L25, beta domain CLOST_1061 5b5dc79b1974ec9419d1f93ad6bb0834 672 Pfam PF02421 Ferrous iron transport protein B 8 165 1.6E-56 T 13-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CLOST_1061 5b5dc79b1974ec9419d1f93ad6bb0834 672 Pfam PF07670 Nucleoside recognition 465 602 5.6E-17 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CLOST_1061 5b5dc79b1974ec9419d1f93ad6bb0834 672 Pfam PF07670 Nucleoside recognition 303 397 2.8E-11 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CLOST_1061 5b5dc79b1974ec9419d1f93ad6bb0834 672 SUPERFAMILY SSF52540 8 169 8.98E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1061 5b5dc79b1974ec9419d1f93ad6bb0834 672 Pfam PF07664 Ferrous iron transport protein B C terminus 408 456 1.1E-12 T 13-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CLOST_1061 5b5dc79b1974ec9419d1f93ad6bb0834 672 Gene3D G3DSA:3.40.50.300 6 202 1.8E-38 T 13-10-2018 CLOST_1061 5b5dc79b1974ec9419d1f93ad6bb0834 672 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 13 598 6.3E-139 T 13-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOST_1810 ef5fae70be180b9603150b7edb68b1a5 301 Pfam PF00753 Metallo-beta-lactamase superfamily 47 245 1.5E-15 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1810 ef5fae70be180b9603150b7edb68b1a5 301 SUPERFAMILY SSF56281 39 289 2.67E-52 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1810 ef5fae70be180b9603150b7edb68b1a5 301 SMART SM00849 49 246 2.2E-6 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1810 ef5fae70be180b9603150b7edb68b1a5 301 Gene3D G3DSA:3.60.15.10 37 290 4.0E-77 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 Gene3D G3DSA:2.40.50.100 61 232 1.4E-72 T 13-10-2018 CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 SUPERFAMILY SSF111369 50 304 2.22E-23 T 13-10-2018 CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 Gene3D G3DSA:2.40.30.170 50 307 1.4E-72 T 13-10-2018 CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 113 380 3.1E-45 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 300 9.8E-18 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 Gene3D G3DSA:2.40.420.20 46 366 1.4E-72 T 13-10-2018 CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 314 335 2.0E-6 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 73 93 2.0E-6 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CLOST_0456 5af1e565679f698c4cb2509c64f41a33 385 Gene3D G3DSA:1.10.287.470 95 198 1.4E-72 T 13-10-2018 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 SUPERFAMILY SSF55174 2 192 1.57E-53 T 13-10-2018 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 5 83 4.0E-20 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 192 29.179 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 4 192 4.5E-64 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 Gene3D G3DSA:1.10.1050.10 6 192 5.2E-63 T 13-10-2018 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 SMART SM00363 84 146 3.8E-17 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 SMART SM01390 3 83 5.4E-27 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 Pfam PF01479 S4 domain 84 131 3.1E-19 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_0152 a6bc6313352a176cbe1902dce735e4de 192 Gene3D G3DSA:3.10.290.10 83 177 5.2E-63 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_2397 f426106dcb26e44c035d2534d152d6ca 184 Pfam PF14345 GDYXXLXY protein 32 168 5.7E-24 T 13-10-2018 IPR025833 GDYXXLXY protein CLOST_0889 19ba099338873fca0dc28e3541fd5917 142 Gene3D G3DSA:2.40.50.100 61 140 8.7E-32 T 13-10-2018 CLOST_0889 19ba099338873fca0dc28e3541fd5917 142 SUPERFAMILY SSF51230 65 140 2.22E-25 T 13-10-2018 IPR011053 Single hybrid motif CLOST_0889 19ba099338873fca0dc28e3541fd5917 142 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 4 140 9.8E-41 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CLOST_0889 19ba099338873fca0dc28e3541fd5917 142 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 69 82 3.6E-19 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CLOST_0889 19ba099338873fca0dc28e3541fd5917 142 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 86 100 3.6E-19 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CLOST_0889 19ba099338873fca0dc28e3541fd5917 142 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 101 114 3.6E-19 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CLOST_0889 19ba099338873fca0dc28e3541fd5917 142 Pfam PF00364 Biotin-requiring enzyme 65 139 8.7E-24 T 13-10-2018 IPR000089 Biotin/lipoyl attachment CLOST_0889 19ba099338873fca0dc28e3541fd5917 142 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 96 113 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_2557 03c25f110718e7211a7ff041a508595f 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 1.9E-27 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_2557 03c25f110718e7211a7ff041a508595f 231 SMART SM00448 3 113 3.2E-45 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2557 03c25f110718e7211a7ff041a508595f 231 SMART SM00862 152 228 1.2E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_2557 03c25f110718e7211a7ff041a508595f 231 Gene3D G3DSA:3.40.50.2300 1 130 7.3E-38 T 13-10-2018 CLOST_2557 03c25f110718e7211a7ff041a508595f 231 Gene3D G3DSA:1.10.10.10 131 231 2.2E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2557 03c25f110718e7211a7ff041a508595f 231 Pfam PF00072 Response regulator receiver domain 5 114 9.4E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2557 03c25f110718e7211a7ff041a508595f 231 SUPERFAMILY SSF52172 2 128 1.42E-40 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_2557 03c25f110718e7211a7ff041a508595f 231 SUPERFAMILY SSF46894 128 229 1.96E-30 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_2250 96af11062d26a3804dfdccfbdca50b7d 326 Pfam PF00005 ABC transporter 26 184 5.5E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2250 96af11062d26a3804dfdccfbdca50b7d 326 Gene3D G3DSA:3.40.50.300 3 325 3.7E-102 T 13-10-2018 CLOST_2250 96af11062d26a3804dfdccfbdca50b7d 326 SUPERFAMILY SSF52540 5 255 1.57E-71 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2250 96af11062d26a3804dfdccfbdca50b7d 326 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2250 96af11062d26a3804dfdccfbdca50b7d 326 SMART SM00382 34 234 1.6E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2250 96af11062d26a3804dfdccfbdca50b7d 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 1.5E-19 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_2250 96af11062d26a3804dfdccfbdca50b7d 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 3.6E-29 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 SMART SM00287 28 90 0.005 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 SMART SM00287 92 154 5.0E-8 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 Gene3D G3DSA:2.30.30.40 94 158 5.2E-15 T 13-10-2018 CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 SUPERFAMILY SSF54001 165 291 2.35E-39 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 Gene3D G3DSA:3.90.1720.10 167 292 9.5E-43 T 13-10-2018 CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 SUPERFAMILY SSF50044 119 151 6.68E-5 T 13-10-2018 IPR036028 SH3-like domain superfamily GO:0005515 CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 Pfam PF00877 NlpC/P60 family 180 289 5.6E-27 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 Gene3D G3DSA:2.30.30.40 26 90 4.0E-9 T 13-10-2018 CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 Pfam PF08239 Bacterial SH3 domain 100 151 4.4E-12 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type CLOST_1403 41d34fdaea4377aab7f2bd8af648850b 292 Pfam PF08239 Bacterial SH3 domain 40 85 2.0E-6 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type CLOST_2351 9ca34742695a513e4783041e11e47a2a 164 SUPERFAMILY SSF140566 2 132 2.35E-12 T 13-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 CLOST_2351 9ca34742695a513e4783041e11e47a2a 164 Gene3D G3DSA:1.20.58.300 2 131 3.7E-5 T 13-10-2018 CLOST_2351 9ca34742695a513e4783041e11e47a2a 164 Pfam PF05130 FlgN protein 1 146 4.3E-16 T 13-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CLOST_2543 3b83425ebdec1be5ef6a5e6507a12532 149 Gene3D G3DSA:3.20.80.10 1 149 3.4E-36 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily CLOST_2543 3b83425ebdec1be5ef6a5e6507a12532 149 SMART SM00871 1 149 8.3E-28 T 13-10-2018 IPR010499 Bacterial transcription activator, effector binding CLOST_2543 3b83425ebdec1be5ef6a5e6507a12532 149 Pfam PF14526 Integron-associated effector binding protein 4 148 4.5E-38 T 13-10-2018 IPR029441 Integron-associated effector binding protein CLOST_2543 3b83425ebdec1be5ef6a5e6507a12532 149 SUPERFAMILY SSF55136 1 149 9.77E-28 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily CLOST_0763 24b3fbb4805076e67472d36605e78a80 334 Pfam PF03773 Predicted permease 39 327 2.0E-67 T 13-10-2018 IPR005524 Predicted permease DUF318 CLOST_1296 3266d225ec1ad295fed88fd3fd14723a 413 PIRSF PIRSF000412 1 409 3.0E-176 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CLOST_1296 3266d225ec1ad295fed88fd3fd14723a 413 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 409 53.51 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CLOST_1296 3266d225ec1ad295fed88fd3fd14723a 413 Pfam PF00464 Serine hydroxymethyltransferase 6 382 4.9E-179 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CLOST_1296 3266d225ec1ad295fed88fd3fd14723a 413 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 13-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CLOST_1296 3266d225ec1ad295fed88fd3fd14723a 413 Gene3D G3DSA:3.90.1150.10 8 389 1.4E-191 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1296 3266d225ec1ad295fed88fd3fd14723a 413 Gene3D G3DSA:3.40.640.10 35 285 1.4E-191 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1296 3266d225ec1ad295fed88fd3fd14723a 413 SUPERFAMILY SSF53383 3 409 6.48E-181 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1366 28528904fe7a7320080e19b8129fd8e7 115 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 2.2E-26 T 13-10-2018 CLOST_1366 28528904fe7a7320080e19b8129fd8e7 115 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 6.6E-35 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CLOST_1366 28528904fe7a7320080e19b8129fd8e7 115 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.96 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CLOST_1366 28528904fe7a7320080e19b8129fd8e7 115 Gene3D G3DSA:3.30.460.10 2 108 2.1E-36 T 13-10-2018 CLOST_1366 28528904fe7a7320080e19b8129fd8e7 115 SUPERFAMILY SSF81301 1 113 3.76E-38 T 13-10-2018 CLOST_0249 bf592df16438e545bb29313cd9ca46db 217 SUPERFAMILY SSF143414 155 208 4.71E-5 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0249 bf592df16438e545bb29313cd9ca46db 217 PIRSF PIRSF012290 1 217 2.6E-86 T 13-10-2018 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0031469 CLOST_0249 bf592df16438e545bb29313cd9ca46db 217 TIGRFAM TIGR04502 microcomp_EutL: microcompartment protein EutL 4 216 1.9E-112 T 13-10-2018 IPR030983 Ethanolamine utilization protein EutL GO:0005198 CLOST_0249 bf592df16438e545bb29313cd9ca46db 217 Pfam PF00936 BMC domain 35 106 2.3E-12 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0249 bf592df16438e545bb29313cd9ca46db 217 Gene3D G3DSA:3.30.70.1810 107 217 4.8E-53 T 13-10-2018 CLOST_0249 bf592df16438e545bb29313cd9ca46db 217 Gene3D G3DSA:3.30.70.1810 7 106 5.1E-47 T 13-10-2018 CLOST_0249 bf592df16438e545bb29313cd9ca46db 217 SMART SM00877 145 214 5.7E-9 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0249 bf592df16438e545bb29313cd9ca46db 217 SMART SM00877 34 121 6.5E-8 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0172 4cfeb821d3ae520da17499c907331122 444 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 430 7.7E-11 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 2.9E-17 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.9E-17 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 2.9E-17 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 2.9E-17 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 2.9E-17 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 306 3.4E-66 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 SUPERFAMILY SSF51905 3 314 1.2E-44 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0172 4cfeb821d3ae520da17499c907331122 444 Gene3D G3DSA:3.50.50.60 118 242 1.6E-106 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 3.6E-23 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 3.6E-23 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.6E-23 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 3.6E-23 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.6E-23 T 13-10-2018 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 Gene3D G3DSA:3.30.390.30 326 444 1.2E-28 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 SUPERFAMILY SSF55424 322 442 1.89E-28 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_0172 4cfeb821d3ae520da17499c907331122 444 Gene3D G3DSA:3.50.50.60 4 314 1.6E-106 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Pfam PF00013 KH domain 553 610 3.7E-9 T 13-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Gene3D G3DSA:3.30.230.70 233 547 1.6E-115 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 316 3.1E-11 T 13-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Gene3D G3DSA:2.40.50.140 548 669 1.5E-47 T 13-10-2018 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Gene3D G3DSA:3.30.230.70 2 232 9.9E-81 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 SMART SM00316 617 687 7.7E-20 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Pfam PF01138 3' exoribonuclease family, domain 1 320 453 5.9E-19 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Pfam PF01138 3' exoribonuclease family, domain 1 12 142 1.0E-20 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 SUPERFAMILY SSF54791 552 637 8.91E-22 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 SMART SM00322 549 614 5.1E-13 T 13-10-2018 IPR004087 K Homology domain GO:0003676 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 SUPERFAMILY SSF50249 617 693 1.87E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 690 30.311 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 688 0.0 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 PIRSF PIRSF005499 1 699 1.7E-293 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Pfam PF03725 3' exoribonuclease family, domain 2 146 208 3.6E-15 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Pfam PF03725 3' exoribonuclease family, domain 2 456 524 1.4E-5 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 SUPERFAMILY SSF55666 447 546 3.14E-28 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 Pfam PF00575 S1 RNA binding domain 616 687 6.0E-15 T 13-10-2018 IPR003029 S1 domain GO:0003676 CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 SUPERFAMILY SSF54211 288 484 3.24E-47 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 SUPERFAMILY SSF54211 5 142 1.01E-48 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_1684 57160f89209beece67ed3d32d08e92b9 699 SUPERFAMILY SSF55666 143 234 1.44E-27 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_0463 f0203de91074c3c640ba8f009279cbae 479 Gene3D G3DSA:3.20.140.10 6 467 1.2E-206 T 13-10-2018 CLOST_0463 f0203de91074c3c640ba8f009279cbae 479 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 151 344 1.8E-10 T 13-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CLOST_0463 f0203de91074c3c640ba8f009279cbae 479 PIRSF PIRSF000484 1 477 7.0E-163 T 13-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CLOST_0463 f0203de91074c3c640ba8f009279cbae 479 SUPERFAMILY SSF51690 135 472 2.52E-125 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CLOST_0463 f0203de91074c3c640ba8f009279cbae 479 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 6 463 5.2E-177 T 13-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CLOST_0463 f0203de91074c3c640ba8f009279cbae 479 Gene3D G3DSA:3.20.20.70 147 316 1.2E-206 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0463 f0203de91074c3c640ba8f009279cbae 479 SUPERFAMILY SSF54675 3 134 2.59E-50 T 13-10-2018 CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 Pfam PF04851 Type III restriction enzyme, res subunit 204 368 1.9E-15 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 SMART SM00490 503 600 5.6E-4 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 Gene3D G3DSA:3.40.50.300 193 387 4.6E-65 T 13-10-2018 CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 Gene3D G3DSA:1.10.8.630 9 114 2.2E-13 T 13-10-2018 CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 Hamap MF_00983 Probable primosomal protein N' [priA]. 11 747 21.848 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 TIGRFAM TIGR00595 priA: primosomal protein N' 229 745 8.6E-182 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 SUPERFAMILY SSF52540 224 610 6.89E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 SMART SM00487 202 400 1.4E-15 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_1857 caf6f0bf8a9995cc1d14b34faa86c5bc 748 Pfam PF00271 Helicase conserved C-terminal domain 516 599 1.1E-6 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0176 c0e1eb9afa6ca7ac0194b70f427a3651 581 SUPERFAMILY SSF58104 251 580 1.96E-61 T 13-10-2018 CLOST_0176 c0e1eb9afa6ca7ac0194b70f427a3651 581 SUPERFAMILY SSF103190 106 185 5.1E-11 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0176 c0e1eb9afa6ca7ac0194b70f427a3651 581 Gene3D G3DSA:1.10.287.950 245 580 5.0E-60 T 13-10-2018 CLOST_0176 c0e1eb9afa6ca7ac0194b70f427a3651 581 SMART SM00283 305 580 2.3E-56 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0176 c0e1eb9afa6ca7ac0194b70f427a3651 581 Pfam PF17201 Cache 3/Cache 2 fusion domain 35 180 7.3E-31 T 13-10-2018 IPR033462 Cache 3/Cache 2 fusion domain CLOST_0176 c0e1eb9afa6ca7ac0194b70f427a3651 581 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 382 532 9.0E-37 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2258 928f5d5fd93e06396fb497fb87f910c8 192 Pfam PF13302 Acetyltransferase (GNAT) domain 12 147 5.4E-14 T 13-10-2018 IPR000182 GNAT domain CLOST_2258 928f5d5fd93e06396fb497fb87f910c8 192 Gene3D G3DSA:3.40.630.30 2 180 2.0E-38 T 13-10-2018 CLOST_2258 928f5d5fd93e06396fb497fb87f910c8 192 SUPERFAMILY SSF55729 4 171 3.48E-34 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1552 4becedde4ce38025c7b86ff380945bab 644 Pfam PF13514 AAA domain 1 60 1.4E-5 T 13-10-2018 IPR038734 Uncharacterized protein YhaN, AAA domain CLOST_1552 4becedde4ce38025c7b86ff380945bab 644 SUPERFAMILY SSF75712 308 395 1.31E-5 T 13-10-2018 CLOST_1552 4becedde4ce38025c7b86ff380945bab 644 SUPERFAMILY SSF52540 1 179 9.66E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1552 4becedde4ce38025c7b86ff380945bab 644 Gene3D G3DSA:3.40.50.300 1 263 8.9E-22 T 13-10-2018 CLOST_2102 8f42060eef3201da1cf52bc3503968f2 273 SUPERFAMILY SSF56524 122 270 1.83E-7 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 CLOST_2102 8f42060eef3201da1cf52bc3503968f2 273 Pfam PF00174 Oxidoreductase molybdopterin binding domain 123 267 9.9E-6 T 13-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 SUPERFAMILY SSF55073 565 708 4.24E-21 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 561 708 7.5E-22 T 13-10-2018 IPR000160 GGDEF domain CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 Gene3D G3DSA:3.30.70.270 554 712 8.8E-24 T 13-10-2018 CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 294 495 2.4E-26 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 Gene3D G3DSA:3.40.190.10 376 469 1.5E-43 T 13-10-2018 CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 SMART SM00267 549 716 8.0E-8 T 13-10-2018 IPR000160 GGDEF domain CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 Gene3D G3DSA:3.40.190.10 137 232 8.9E-33 T 13-10-2018 CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 60 260 1.6E-20 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 SMART SM00062 293 505 7.8E-6 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 SMART SM00062 53 270 1.6E-7 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 SUPERFAMILY SSF53850 285 497 3.81E-33 T 13-10-2018 CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 SUPERFAMILY SSF53850 60 265 6.44E-29 T 13-10-2018 CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 Pfam PF00990 Diguanylate cyclase, GGDEF domain 561 708 3.2E-22 T 13-10-2018 IPR000160 GGDEF domain CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 Gene3D G3DSA:3.40.190.10 42 263 8.9E-33 T 13-10-2018 CLOST_0496 57b8edfd5d919b0f523ba77e6d2bc3eb 716 Gene3D G3DSA:3.40.190.10 284 500 1.5E-43 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 Pfam PF00204 DNA gyrase B 228 397 2.6E-63 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 SUPERFAMILY SSF55874 12 221 1.18E-73 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 SMART SM00433 41 634 0.0 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 ProSitePatterns PS00177 DNA topoisomerase II signature. 429 437 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 SUPERFAMILY SSF54211 228 398 2.85E-59 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 275 288 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 573 589 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 41 56 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 493 509 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 511 528 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 531 543 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 76 89 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 427 441 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR00418 DNA topoisomerase II family signature 119 133 2.9E-72 T 13-10-2018 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 Pfam PF01751 Toprim domain 426 537 8.1E-19 T 13-10-2018 IPR006171 TOPRIM domain CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 SMART SM00387 37 181 8.0E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 9 641 93.775 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 Gene3D G3DSA:3.30.230.10 227 405 6.3E-74 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 179 4.4E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 12 641 0.0 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 SUPERFAMILY SSF56719 401 633 8.11E-92 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 227 249 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 381 401 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 12 22 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 319 335 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 367 381 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 594 606 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 477 486 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 PRINTS PR01159 DNA gyrase subunit B signature 610 626 1.5E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 630 4.9E-31 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 Gene3D G3DSA:3.30.565.10 8 226 1.3E-91 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0005 1ac5c30eaef3dd92efe8ab192d4eab1c 641 Gene3D G3DSA:3.40.50.670 406 641 3.5E-110 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CLOST_1468 923fcc953a9ce23ecac3804dbbeadc8a 220 TIGRFAM TIGR00017 cmk: cytidylate kinase 1 210 3.1E-79 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CLOST_1468 923fcc953a9ce23ecac3804dbbeadc8a 220 Hamap MF_00238 Cytidylate kinase [cmk]. 1 215 34.381 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CLOST_1468 923fcc953a9ce23ecac3804dbbeadc8a 220 SUPERFAMILY SSF52540 1 213 1.22E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1468 923fcc953a9ce23ecac3804dbbeadc8a 220 Pfam PF02224 Cytidylate kinase 3 212 3.7E-79 T 13-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CLOST_1468 923fcc953a9ce23ecac3804dbbeadc8a 220 Gene3D G3DSA:3.40.50.300 1 216 5.5E-85 T 13-10-2018 CLOST_1735 50b5d43a9c13631eb06a239edba0ee05 477 Gene3D G3DSA:3.30.750.140 330 451 6.1E-18 T 13-10-2018 IPR038610 FliK-like, C-terminal domain superfamily CLOST_1735 50b5d43a9c13631eb06a239edba0ee05 477 Pfam PF02120 Flagellar hook-length control protein FliK 352 430 3.2E-20 T 13-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CLOST_0445 1b9534d0c2107794cc58ba4c6c2245bc 337 SUPERFAMILY SSF55729 163 320 3.28E-18 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0445 1b9534d0c2107794cc58ba4c6c2245bc 337 Gene3D G3DSA:3.40.630.30 128 321 3.1E-13 T 13-10-2018 CLOST_1630 8db35d7710ccad9803ebcc86cd940991 441 Gene3D G3DSA:3.60.21.10 40 341 1.5E-136 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like CLOST_1630 8db35d7710ccad9803ebcc86cd940991 441 Pfam PF00149 Calcineurin-like phosphoesterase 42 283 1.3E-17 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CLOST_1630 8db35d7710ccad9803ebcc86cd940991 441 PIRSF PIRSF034890 1 437 6.9E-93 T 13-10-2018 IPR012365 Phosphoesterase, lmo2642-related CLOST_1630 8db35d7710ccad9803ebcc86cd940991 441 SUPERFAMILY SSF56300 38 327 7.08E-35 T 13-10-2018 CLOST_1630 8db35d7710ccad9803ebcc86cd940991 441 Gene3D G3DSA:1.10.246.180 342 423 1.5E-136 T 13-10-2018 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 SMART SM00788 3 422 2.8E-275 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 422 2.1E-169 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 13-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 Gene3D G3DSA:3.90.170.10 265 427 1.6E-71 T 13-10-2018 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 Gene3D G3DSA:3.40.440.10 5 253 2.2E-100 T 13-10-2018 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 193.415 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 Gene3D G3DSA:1.10.300.10 100 199 2.2E-100 T 13-10-2018 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 Pfam PF00709 Adenylosuccinate synthetase 5 421 7.7E-183 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 13-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CLOST_2562 b60cd085b14687e29c9e3aa87d4e6ebb 427 SUPERFAMILY SSF52540 2 426 1.91E-169 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0789 9edcbe2a8e8170f341027f6a8dcfab6e 144 Pfam PF12802 MarR family 33 91 2.4E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0789 9edcbe2a8e8170f341027f6a8dcfab6e 144 Gene3D G3DSA:1.10.10.10 1 141 2.4E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0789 9edcbe2a8e8170f341027f6a8dcfab6e 144 SUPERFAMILY SSF46785 21 141 2.66E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0789 9edcbe2a8e8170f341027f6a8dcfab6e 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 7.8E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0789 9edcbe2a8e8170f341027f6a8dcfab6e 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 7.8E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0789 9edcbe2a8e8170f341027f6a8dcfab6e 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 7.8E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0789 9edcbe2a8e8170f341027f6a8dcfab6e 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 7.8E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0789 9edcbe2a8e8170f341027f6a8dcfab6e 144 SMART SM00347 26 128 8.9E-6 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0688 682fc167539707b3fe8a17283adb0e1e 401 PIRSF PIRSF031134 1 399 5.2E-151 T 13-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 CLOST_0688 682fc167539707b3fe8a17283adb0e1e 401 SUPERFAMILY SSF56112 4 396 8.51E-84 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily CLOST_0688 682fc167539707b3fe8a17283adb0e1e 401 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 401 163.38 T 13-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 CLOST_0688 682fc167539707b3fe8a17283adb0e1e 401 Gene3D G3DSA:3.30.200.20 1 116 7.3E-36 T 13-10-2018 CLOST_0688 682fc167539707b3fe8a17283adb0e1e 401 Pfam PF01636 Phosphotransferase enzyme family 218 278 4.1E-10 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase CLOST_0688 682fc167539707b3fe8a17283adb0e1e 401 Gene3D G3DSA:3.90.1200.10 118 400 1.8E-100 T 13-10-2018 CLOST_0688 682fc167539707b3fe8a17283adb0e1e 401 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 34 396 1.7E-101 T 13-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 458 1.5E-87 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 379 395 1.2E-12 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 222 235 1.2E-12 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 419 433 1.2E-12 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 PRINTS PR01042 Aspartyl-tRNA synthetase signature 206 218 1.2E-12 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 464 3.9E-192 T 13-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 Pfam PF01336 OB-fold nucleic acid binding domain 23 98 7.8E-9 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 Gene3D G3DSA:3.30.930.10 107 462 1.5E-115 T 13-10-2018 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 Gene3D G3DSA:2.40.50.140 2 106 3.6E-18 T 13-10-2018 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 7 464 45.794 T 13-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 SUPERFAMILY SSF55681 103 461 4.79E-100 T 13-10-2018 CLOST_2369 87a90c3c41b4efd0dee4d54ae544b027 464 SUPERFAMILY SSF50249 14 100 2.45E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 18 143 4.2E-24 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 SMART SM00047 1 147 7.1E-40 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 Gene3D G3DSA:1.10.530.10 4 145 1.2E-46 T 13-10-2018 CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 SUPERFAMILY SSF54001 165 277 2.4E-23 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 Pfam PF00877 NlpC/P60 family 171 269 9.5E-16 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 Gene3D G3DSA:4.10.80.30 57 82 1.2E-46 T 13-10-2018 CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 PRINTS PR01002 Flagellar protein FlgJ signature 39 60 2.2E-9 T 13-10-2018 CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 PRINTS PR01002 Flagellar protein FlgJ signature 83 104 2.2E-9 T 13-10-2018 CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 PRINTS PR01002 Flagellar protein FlgJ signature 124 142 2.2E-9 T 13-10-2018 CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 PRINTS PR01002 Flagellar protein FlgJ signature 61 82 2.2E-9 T 13-10-2018 CLOST_1504 507b77837562295d28eaaf5b4689c9a1 353 Gene3D G3DSA:3.90.1720.10 146 278 1.5E-26 T 13-10-2018 CLOST_2067 1965876d2ce7885ae00fc00addb6aa5c 281 PIRSF PIRSF006483 1 281 1.7E-71 T 13-10-2018 IPR003740 Uncharacterised membrane protein YitT CLOST_2067 1965876d2ce7885ae00fc00addb6aa5c 281 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 215 5.3E-53 T 13-10-2018 IPR003740 Uncharacterised membrane protein YitT CLOST_2067 1965876d2ce7885ae00fc00addb6aa5c 281 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 7.3E-16 T 13-10-2018 IPR019264 Domain of unknown function DUF2179 CLOST_2067 1965876d2ce7885ae00fc00addb6aa5c 281 Gene3D G3DSA:3.30.70.120 194 267 2.3E-16 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CLOST_0411 5e57297b48105e5fab288330ae35abd4 225 Gene3D G3DSA:2.40.30.20 101 202 8.9E-32 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_0411 5e57297b48105e5fab288330ae35abd4 225 SUPERFAMILY SSF63380 1 92 2.98E-26 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CLOST_0411 5e57297b48105e5fab288330ae35abd4 225 SUPERFAMILY SSF63380 92 193 2.04E-31 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CLOST_0411 5e57297b48105e5fab288330ae35abd4 225 Gene3D G3DSA:2.40.30.20 1 88 8.5E-31 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_0411 5e57297b48105e5fab288330ae35abd4 225 Pfam PF00677 Lumazine binding domain 99 183 3.3E-22 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0411 5e57297b48105e5fab288330ae35abd4 225 Pfam PF00677 Lumazine binding domain 3 86 3.8E-24 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0411 5e57297b48105e5fab288330ae35abd4 225 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 4.4E-75 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0411 5e57297b48105e5fab288330ae35abd4 225 PIRSF PIRSF000498 1 209 3.1E-75 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_2315 aefaaa60ec3178c7939c76eb3af3b938 457 Gene3D G3DSA:3.40.50.12240 1 457 6.0E-172 T 13-10-2018 CLOST_2315 aefaaa60ec3178c7939c76eb3af3b938 457 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2315 aefaaa60ec3178c7939c76eb3af3b938 457 SUPERFAMILY SSF52540 79 355 7.97E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2315 aefaaa60ec3178c7939c76eb3af3b938 457 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 12 75 8.0E-6 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2315 aefaaa60ec3178c7939c76eb3af3b938 457 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 457 55.178 T 13-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2315 aefaaa60ec3178c7939c76eb3af3b938 457 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 4.6E-67 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_0223 d771b484b3496bc50bd690236c5724fd 191 Pfam PF04011 LemA family 11 187 3.2E-68 T 13-10-2018 IPR007156 LemA CLOST_0223 d771b484b3496bc50bd690236c5724fd 191 Gene3D G3DSA:1.20.1440.20 21 188 5.3E-69 T 13-10-2018 IPR023353 LemA-like domain superfamily CLOST_0223 d771b484b3496bc50bd690236c5724fd 191 SUPERFAMILY SSF140478 30 177 4.97E-54 T 13-10-2018 IPR023353 LemA-like domain superfamily CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 Gene3D G3DSA:3.40.640.10 62 283 1.8E-133 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 SUPERFAMILY SSF53383 2 392 1.99E-112 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 Gene3D G3DSA:3.90.1150.10 25 388 1.8E-133 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 9.5E-11 T 13-10-2018 CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 9.5E-11 T 13-10-2018 CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 9.5E-11 T 13-10-2018 CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 227 251 9.5E-11 T 13-10-2018 CLOST_1239 8e9ecced63b551369ae5b651437e1667 393 Pfam PF00155 Aminotransferase class I and II 31 388 8.5E-72 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 Pfam PF01926 50S ribosome-binding GTPase 3 119 2.2E-23 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 Gene3D G3DSA:3.10.20.30 46 363 9.6E-155 T 13-10-2018 IPR012675 Beta-grasp domain superfamily CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 PIRSF PIRSF006641 1 365 1.6E-155 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 SUPERFAMILY SSF81271 280 365 4.8E-31 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 365 43.69 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 Gene3D G3DSA:1.10.150.300 111 197 9.6E-155 T 13-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 Gene3D G3DSA:3.40.50.300 1 279 9.6E-155 T 13-10-2018 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 68 83 1.0E-36 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 103 1.0E-36 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 1.0E-36 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 1.0E-36 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 365 6.2E-154 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 SUPERFAMILY SSF52540 1 302 2.39E-85 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1906 ff475eb641182d2b425f1ac1bd1afcd3 365 Pfam PF06071 Protein of unknown function (DUF933) 280 364 6.8E-36 T 13-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 CLOST_2198 bc1adda545c331f2fe0b7bcfbcdc4145 208 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 206 40.401 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2198 bc1adda545c331f2fe0b7bcfbcdc4145 208 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 1.8E-89 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2198 bc1adda545c331f2fe0b7bcfbcdc4145 208 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 13-10-2018 IPR019926 Ribosomal protein L3, conserved site CLOST_2198 bc1adda545c331f2fe0b7bcfbcdc4145 208 Gene3D G3DSA:2.40.30.10 130 208 2.6E-19 T 13-10-2018 CLOST_2198 bc1adda545c331f2fe0b7bcfbcdc4145 208 SUPERFAMILY SSF50447 2 207 3.27E-82 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_2198 bc1adda545c331f2fe0b7bcfbcdc4145 208 Gene3D G3DSA:2.40.50.620 32 91 1.1E-17 T 13-10-2018 CLOST_2198 bc1adda545c331f2fe0b7bcfbcdc4145 208 Pfam PF00297 Ribosomal protein L3 98 180 3.8E-14 T 13-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2392 b191cf685ddfc1515221b80608a31d15 252 PIRSF PIRSF000371 1 49 3.2E-16 T 13-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CLOST_2392 b191cf685ddfc1515221b80608a31d15 252 PIRSF PIRSF000371 43 243 1.7E-42 T 13-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CLOST_2392 b191cf685ddfc1515221b80608a31d15 252 ProSitePatterns PS01087 Radical activating enzymes signature. 16 37 - T 13-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CLOST_2392 b191cf685ddfc1515221b80608a31d15 252 Pfam PF13353 4Fe-4S single cluster domain 14 126 3.5E-18 T 13-10-2018 CLOST_2392 b191cf685ddfc1515221b80608a31d15 252 SUPERFAMILY SSF102114 21 217 3.14E-26 T 13-10-2018 CLOST_2392 b191cf685ddfc1515221b80608a31d15 252 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 4 235 9.1E-84 T 13-10-2018 IPR012838 Pyruvate formate-lyase 1 activating enzyme GO:0043365|GO:0055114 CLOST_2392 b191cf685ddfc1515221b80608a31d15 252 Pfam PF04055 Radical SAM superfamily 24 174 2.7E-26 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_2392 b191cf685ddfc1515221b80608a31d15 252 Gene3D G3DSA:3.20.20.70 1 241 5.9E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 327 8.2E-55 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 329 1.5E-123 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 330 81.593 T 13-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 4.1E-24 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 294 317 4.1E-24 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 4.1E-24 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 4.1E-24 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 2.6E-31 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 2.6E-31 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 2.6E-31 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 2.6E-31 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 308 319 2.6E-31 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 Gene3D G3DSA:3.40.50.1370 5 326 1.3E-136 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 SUPERFAMILY SSF53671 4 331 6.02E-98 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.3E-45 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CLOST_0927 f2087a959d24a505fd5539a86ec7cf1c 332 Gene3D G3DSA:3.40.50.1370 151 316 1.3E-136 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CLOST_2048 21af7103d4c00ba1fef2a2670481461d 169 Gene3D G3DSA:1.10.1760.20 1 162 1.5E-8 T 13-10-2018 CLOST_2048 21af7103d4c00ba1fef2a2670481461d 169 Pfam PF17099 Tryptophan transporter TrpP 2 158 6.9E-46 T 13-10-2018 IPR031360 Tryptophan transporter TrpP CLOST_2048 21af7103d4c00ba1fef2a2670481461d 169 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 156 4.0E-50 T 13-10-2018 CLOST_2318 0bf1102e094c1f27800b432fcc4d196d 103 Pfam PF01990 ATP synthase (F/14-kDa) subunit 6 93 1.5E-19 T 13-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2318 0bf1102e094c1f27800b432fcc4d196d 103 Gene3D G3DSA:3.40.50.10580 3 103 3.7E-23 T 13-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2318 0bf1102e094c1f27800b432fcc4d196d 103 SUPERFAMILY SSF159468 6 103 1.02E-21 T 13-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_1486 a6e4672381426b5577f18de1ee63d2b1 86 Pfam PF00564 PB1 domain 49 82 4.7E-5 T 13-10-2018 IPR000270 PB1 domain GO:0005515 CLOST_1486 a6e4672381426b5577f18de1ee63d2b1 86 Hamap MF_01448 UPF0473 protein . 6 86 15.851 T 13-10-2018 IPR009711 Uncharacterised protein family UPF0473 CLOST_1486 a6e4672381426b5577f18de1ee63d2b1 86 Pfam PF06949 Protein of unknown function (DUF1292) 15 84 2.3E-17 T 13-10-2018 IPR009711 Uncharacterised protein family UPF0473 CLOST_2556 27526241c870db02bf7a52519b813b50 602 SUPERFAMILY SSF55874 429 595 3.54E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2556 27526241c870db02bf7a52519b813b50 602 SUPERFAMILY SSF47384 357 439 4.71E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_2556 27526241c870db02bf7a52519b813b50 602 Gene3D G3DSA:1.10.287.130 368 442 2.2E-25 T 13-10-2018 CLOST_2556 27526241c870db02bf7a52519b813b50 602 SMART SM00091 256 323 1.8E-6 T 13-10-2018 IPR000014 PAS domain CLOST_2556 27526241c870db02bf7a52519b813b50 602 SMART SM00388 372 439 1.1E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_2556 27526241c870db02bf7a52519b813b50 602 Gene3D G3DSA:3.30.450.20 252 367 5.4E-18 T 13-10-2018 CLOST_2556 27526241c870db02bf7a52519b813b50 602 Gene3D G3DSA:1.20.1480.50 160 251 2.6E-13 T 13-10-2018 CLOST_2556 27526241c870db02bf7a52519b813b50 602 SMART SM00387 485 597 5.9E-43 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_2556 27526241c870db02bf7a52519b813b50 602 SUPERFAMILY SSF55785 252 364 1.55E-10 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2556 27526241c870db02bf7a52519b813b50 602 Gene3D G3DSA:3.30.565.10 446 600 1.7E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2556 27526241c870db02bf7a52519b813b50 602 Pfam PF00512 His Kinase A (phospho-acceptor) domain 372 437 4.3E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_2556 27526241c870db02bf7a52519b813b50 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 596 1.0E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_2556 27526241c870db02bf7a52519b813b50 602 Pfam PF00672 HAMP domain 198 244 7.4E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_2556 27526241c870db02bf7a52519b813b50 602 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 254 371 1.3E-10 T 13-10-2018 IPR000014 PAS domain CLOST_2556 27526241c870db02bf7a52519b813b50 602 Pfam PF00989 PAS fold 258 363 9.7E-10 T 13-10-2018 IPR013767 PAS fold GO:0006355 CLOST_2556 27526241c870db02bf7a52519b813b50 602 SMART SM00304 197 249 2.1E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_2556 27526241c870db02bf7a52519b813b50 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 536 3.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2556 27526241c870db02bf7a52519b813b50 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 594 3.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2556 27526241c870db02bf7a52519b813b50 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 575 3.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2556 27526241c870db02bf7a52519b813b50 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 550 3.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2556 27526241c870db02bf7a52519b813b50 602 SUPERFAMILY SSF158472 198 246 5.36E-9 T 13-10-2018 CLOST_1176 cc6f092d075a9dae4de55a109a4e22f4 115 ProDom PD053081 COIL MM0410 AF2262 COILED 60 112 2.0E-13 T 13-10-2018 CLOST_2388 060a8744263937c2db7c540fb7256361 368 Gene3D G3DSA:3.40.50.2000 186 353 5.5E-24 T 13-10-2018 CLOST_2388 060a8744263937c2db7c540fb7256361 368 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 16 180 8.8E-29 T 13-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CLOST_2388 060a8744263937c2db7c540fb7256361 368 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 204 300 4.1E-9 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 CLOST_2388 060a8744263937c2db7c540fb7256361 368 SUPERFAMILY SSF53756 4 365 1.57E-25 T 13-10-2018 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 Gene3D G3DSA:1.10.8.500 322 368 1.8E-6 T 13-10-2018 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 Gene3D G3DSA:1.10.287.950 369 675 6.4E-63 T 13-10-2018 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 SMART SM00304 319 371 2.8E-11 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 349 670 0.003 T 13-10-2018 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 446 627 8.1E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 Gene3D G3DSA:3.30.450.20 192 293 4.8E-41 T 13-10-2018 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 Pfam PF02743 Cache domain 40 281 3.5E-31 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 SMART SM00283 386 675 1.3E-53 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 SUPERFAMILY SSF58104 339 674 1.31E-69 T 13-10-2018 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 414 443 1.7E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 527 556 1.7E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 Pfam PF00672 HAMP domain 322 365 3.6E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 Gene3D G3DSA:3.30.450.20 108 191 4.8E-41 T 13-10-2018 CLOST_1138 2a282c7409137a80a31a6037a8d90392 676 SUPERFAMILY SSF103190 101 200 8.11E-12 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_1090 a1bdd049bdf7bf9a887497bae7464bd5 254 SUPERFAMILY SSF53213 3 251 6.54E-80 T 13-10-2018 CLOST_1090 a1bdd049bdf7bf9a887497bae7464bd5 254 Gene3D G3DSA:3.40.830.10 1 253 4.7E-83 T 13-10-2018 CLOST_1090 a1bdd049bdf7bf9a887497bae7464bd5 254 PIRSF PIRSF006157 1 254 1.3E-80 T 13-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CLOST_1090 a1bdd049bdf7bf9a887497bae7464bd5 254 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 230 3.5E-29 T 13-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CLOST_2207 4622fea589218929b40cdf165e55632d 690 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site CLOST_2207 4622fea589218929b40cdf165e55632d 690 SMART SM00838 597 685 1.2E-57 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like CLOST_2207 4622fea589218929b40cdf165e55632d 690 SUPERFAMILY SSF52540 6 280 1.94E-107 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2207 4622fea589218929b40cdf165e55632d 690 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 688 0.0 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_2207 4622fea589218929b40cdf165e55632d 690 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 1.6E-65 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 Gene3D G3DSA:3.40.50.300 1 290 1.8E-110 T 13-10-2018 CLOST_2207 4622fea589218929b40cdf165e55632d 690 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 179 7.0E-36 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 Pfam PF00679 Elongation factor G C-terminus 597 684 1.5E-32 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like CLOST_2207 4622fea589218929b40cdf165e55632d 690 SUPERFAMILY SSF54980 401 478 3.96E-25 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_2207 4622fea589218929b40cdf165e55632d 690 SUPERFAMILY SSF54980 600 688 1.51E-32 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_2207 4622fea589218929b40cdf165e55632d 690 Gene3D G3DSA:3.30.70.240 601 672 1.1E-91 T 13-10-2018 CLOST_2207 4622fea589218929b40cdf165e55632d 690 Pfam PF14492 Elongation Factor G, domain II 401 474 5.8E-34 T 13-10-2018 CLOST_2207 4622fea589218929b40cdf165e55632d 690 Gene3D G3DSA:3.30.230.10 481 685 1.1E-91 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_2207 4622fea589218929b40cdf165e55632d 690 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 113.459 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_2207 4622fea589218929b40cdf165e55632d 690 Gene3D G3DSA:2.40.30.10 291 397 6.3E-46 T 13-10-2018 CLOST_2207 4622fea589218929b40cdf165e55632d 690 SUPERFAMILY SSF54211 476 595 6.83E-44 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_2207 4622fea589218929b40cdf165e55632d 690 Pfam PF03144 Elongation factor Tu domain 2 321 388 1.6E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 Pfam PF03764 Elongation factor G, domain IV 476 595 1.3E-47 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 SMART SM00889 477 595 7.7E-72 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 SUPERFAMILY SSF50447 264 401 2.12E-37 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_2207 4622fea589218929b40cdf165e55632d 690 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.0E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 PRINTS PR00315 GTP-binding elongation factor signature 12 25 3.0E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.0E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.0E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 PRINTS PR00315 GTP-binding elongation factor signature 130 139 3.0E-16 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_2207 4622fea589218929b40cdf165e55632d 690 Gene3D G3DSA:3.30.70.870 402 480 1.6E-32 T 13-10-2018 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 SUPERFAMILY SSF55821 2 201 6.41E-84 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 37.984 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 SUPERFAMILY SSF142695 203 374 2.88E-71 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 1.9E-76 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 2.9E-85 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 Gene3D G3DSA:3.40.50.10990 204 374 3.6E-74 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 53.153 T 13-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 PIRSF PIRSF001259 1 405 4.3E-185 T 13-10-2018 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 41.475 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 Gene3D G3DSA:3.90.870.10 1 203 8.7E-89 T 13-10-2018 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 210 395 4.2E-82 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CLOST_0412 bf87872a1dfedebda5e7ba5eb56cd739 405 Pfam PF00925 GTP cyclohydrolase II 210 370 2.9E-73 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CLOST_0404 365f8d517160cf9585763e33fd849602 552 SUPERFAMILY SSF109604 373 547 3.14E-36 T 13-10-2018 CLOST_0404 365f8d517160cf9585763e33fd849602 552 SMART SM00471 380 515 1.0E-12 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0404 365f8d517160cf9585763e33fd849602 552 Gene3D G3DSA:1.10.3210.10 364 551 1.2E-64 T 13-10-2018 CLOST_0404 365f8d517160cf9585763e33fd849602 552 Gene3D G3DSA:1.20.1480.50 270 363 1.1E-9 T 13-10-2018 CLOST_0404 365f8d517160cf9585763e33fd849602 552 Gene3D G3DSA:3.30.450.20 93 193 3.7E-22 T 13-10-2018 CLOST_0404 365f8d517160cf9585763e33fd849602 552 Pfam PF00672 HAMP domain 308 356 2.9E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0404 365f8d517160cf9585763e33fd849602 552 SMART SM00304 308 360 6.8E-11 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0404 365f8d517160cf9585763e33fd849602 552 TIGRFAM TIGR00277 HDIG: HDIG domain 384 474 1.0E-8 T 13-10-2018 IPR006675 HDIG domain CLOST_0404 365f8d517160cf9585763e33fd849602 552 Pfam PF01966 HD domain 386 504 1.6E-21 T 13-10-2018 IPR006674 HD domain CLOST_0404 365f8d517160cf9585763e33fd849602 552 Pfam PF02743 Cache domain 53 271 1.0E-23 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0404 365f8d517160cf9585763e33fd849602 552 SUPERFAMILY SSF158472 308 358 3.79E-9 T 13-10-2018 CLOST_2542 6039e710c7a461b68e1af77b7a5b770e 323 Gene3D G3DSA:1.10.10.10 1 63 1.9E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2542 6039e710c7a461b68e1af77b7a5b770e 323 Pfam PF13280 WYL domain 141 317 1.2E-33 T 13-10-2018 IPR026881 WYL domain CLOST_2542 6039e710c7a461b68e1af77b7a5b770e 323 SUPERFAMILY SSF46785 4 59 6.34E-8 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2542 6039e710c7a461b68e1af77b7a5b770e 323 PIRSF PIRSF016838 75 323 2.7E-14 T 13-10-2018 IPR028349 Protein PafC CLOST_2542 6039e710c7a461b68e1af77b7a5b770e 323 PIRSF PIRSF016838 1 57 0.0087 T 13-10-2018 IPR028349 Protein PafC CLOST_2542 6039e710c7a461b68e1af77b7a5b770e 323 Pfam PF08279 HTH domain 5 58 5.3E-14 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 CLOST_1147 f7477adaa2776f77fb6c6d5491490674 342 PIRSF PIRSF000138 183 339 1.6E-55 T 13-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 CLOST_1147 f7477adaa2776f77fb6c6d5491490674 342 PIRSF PIRSF000138 7 190 4.6E-12 T 13-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 CLOST_1147 f7477adaa2776f77fb6c6d5491490674 342 Gene3D G3DSA:3.20.20.70 36 340 6.2E-69 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1147 f7477adaa2776f77fb6c6d5491490674 342 Pfam PF01070 FMN-dependent dehydrogenase 196 337 1.7E-54 T 13-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 CLOST_1147 f7477adaa2776f77fb6c6d5491490674 342 SUPERFAMILY SSF51395 38 335 2.72E-51 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 SUPERFAMILY SSF82714 183 264 1.57E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Gene3D G3DSA:3.30.70.1430 40 811 3.1E-267 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 SUPERFAMILY SSF82866 803 1024 4.97E-43 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 SUPERFAMILY SSF82693 558 659 2.41E-8 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 SUPERFAMILY SSF82714 716 800 2.09E-10 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Gene3D G3DSA:3.30.2090.10 178 268 3.1E-267 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Gene3D G3DSA:1.20.1640.10 11 504 3.1E-267 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Gene3D G3DSA:3.30.70.1440 664 860 3.1E-267 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 SUPERFAMILY SSF82693 42 134 6.1E-20 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Gene3D G3DSA:3.30.2090.10 714 803 3.1E-267 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Gene3D G3DSA:3.30.70.1430 559 663 3.1E-267 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Pfam PF00873 AcrB/AcrD/AcrF family 5 1019 7.0E-216 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 2.1E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 2.1E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.1E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 2.1E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 2.1E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 2.1E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 2.1E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.1E-36 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Gene3D G3DSA:1.20.1640.10 505 1017 3.1E-267 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 Gene3D G3DSA:3.30.70.1320 134 324 3.1E-267 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 SUPERFAMILY SSF82866 289 488 1.83E-37 T 13-10-2018 CLOST_0721 b061d1e55d2faebff24019636dff9b2a 1029 SUPERFAMILY SSF82693 135 312 2.88E-15 T 13-10-2018 CLOST_1388 1542c7d30c69f75d743396c819f26b16 90 Pfam PF03776 Septum formation topological specificity factor MinE 15 87 5.0E-23 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CLOST_1388 1542c7d30c69f75d743396c819f26b16 90 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 3 88 7.1E-21 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CLOST_1388 1542c7d30c69f75d743396c819f26b16 90 Hamap MF_00262 Cell division topological specificity factor [minE]. 1 89 15.17 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 CLOST_1388 1542c7d30c69f75d743396c819f26b16 90 SUPERFAMILY SSF55229 33 89 7.06E-10 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 CLOST_1388 1542c7d30c69f75d743396c819f26b16 90 Gene3D G3DSA:3.30.1070.10 1 84 8.6E-15 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 CLOST_2313 ae3075618ab4a60696c648870a82c7d9 178 Gene3D G3DSA:3.30.160.100 1 106 2.6E-27 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like CLOST_2313 ae3075618ab4a60696c648870a82c7d9 178 Gene3D G3DSA:3.30.505.50 132 178 1.5E-24 T 13-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily CLOST_2313 ae3075618ab4a60696c648870a82c7d9 178 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 97 2.0E-24 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 CLOST_2313 ae3075618ab4a60696c648870a82c7d9 178 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 178 22.844 T 13-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CLOST_2313 ae3075618ab4a60696c648870a82c7d9 178 SUPERFAMILY SSF69754 1 99 8.24E-28 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like CLOST_2313 ae3075618ab4a60696c648870a82c7d9 178 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 5.9E-24 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 CLOST_2313 ae3075618ab4a60696c648870a82c7d9 178 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 121 174 5.5E-27 T 13-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CLOST_0555 dced7ca507d7dfedb3bf1ee8ff61e95a 720 Gene3D G3DSA:1.10.486.10 381 543 8.0E-124 T 13-10-2018 CLOST_0555 dced7ca507d7dfedb3bf1ee8ff61e95a 720 SUPERFAMILY SSF52540 4 637 8.08E-180 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0555 dced7ca507d7dfedb3bf1ee8ff61e95a 720 Gene3D G3DSA:3.40.50.300 278 628 8.0E-124 T 13-10-2018 CLOST_0555 dced7ca507d7dfedb3bf1ee8ff61e95a 720 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 270 3.6E-83 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CLOST_0555 dced7ca507d7dfedb3bf1ee8ff61e95a 720 Gene3D G3DSA:1.10.10.160 110 185 2.6E-105 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily CLOST_0555 dced7ca507d7dfedb3bf1ee8ff61e95a 720 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 3 716 1.8E-282 T 13-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CLOST_0555 dced7ca507d7dfedb3bf1ee8ff61e95a 720 Pfam PF13361 UvrD-like helicase C-terminal domain 275 611 3.1E-73 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CLOST_0555 dced7ca507d7dfedb3bf1ee8ff61e95a 720 Gene3D G3DSA:3.40.50.300 6 272 2.6E-105 T 13-10-2018 CLOST_1433 e2366d4b6214307aa34e62f4fdb4e626 72 Gene3D G3DSA:3.30.110.40 1 72 4.6E-14 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_1433 e2366d4b6214307aa34e62f4fdb4e626 72 SUPERFAMILY SSF64307 1 70 6.93E-15 T 13-10-2018 IPR036868 TusA-like domain superfamily CLOST_1433 e2366d4b6214307aa34e62f4fdb4e626 72 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 4 28 - T 13-10-2018 IPR001455 TusA-like domain CLOST_1433 e2366d4b6214307aa34e62f4fdb4e626 72 Pfam PF01206 Sulfurtransferase TusA 2 70 1.1E-15 T 13-10-2018 IPR001455 TusA-like domain CLOST_1925 906c8b461bb0dae9d6b172d2c8b69c24 194 Gene3D G3DSA:3.40.920.10 1 193 1.1E-45 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1925 906c8b461bb0dae9d6b172d2c8b69c24 194 SUPERFAMILY SSF53323 4 190 4.58E-33 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1925 906c8b461bb0dae9d6b172d2c8b69c24 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 189 7.4E-35 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CLOST_2376 0ae0adceecaa40a2c18ba01b1f0fcfb2 278 Gene3D G3DSA:3.40.50.720 102 234 3.6E-83 T 13-10-2018 CLOST_2376 0ae0adceecaa40a2c18ba01b1f0fcfb2 278 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 3 275 28.49 T 13-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CLOST_2376 0ae0adceecaa40a2c18ba01b1f0fcfb2 278 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 6 254 5.2E-64 T 13-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CLOST_2376 0ae0adceecaa40a2c18ba01b1f0fcfb2 278 SUPERFAMILY SSF53223 5 102 2.88E-26 T 13-10-2018 CLOST_2376 0ae0adceecaa40a2c18ba01b1f0fcfb2 278 Gene3D G3DSA:3.40.50.10860 6 251 3.6E-83 T 13-10-2018 CLOST_2376 0ae0adceecaa40a2c18ba01b1f0fcfb2 278 SUPERFAMILY SSF51735 103 253 2.9E-27 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_2376 0ae0adceecaa40a2c18ba01b1f0fcfb2 278 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 8 90 1.9E-27 T 13-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CLOST_1717 c451280dcbf3d7a165262aa80407cfa0 297 Gene3D G3DSA:3.40.50.300 31 272 2.4E-57 T 13-10-2018 CLOST_1717 c451280dcbf3d7a165262aa80407cfa0 297 SUPERFAMILY SSF52540 31 292 3.47E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1717 c451280dcbf3d7a165262aa80407cfa0 297 Pfam PF13614 AAA domain 31 197 8.8E-20 T 13-10-2018 IPR025669 AAA domain CLOST_1717 c451280dcbf3d7a165262aa80407cfa0 297 PIRSF PIRSF003092 4 295 4.4E-89 T 13-10-2018 IPR025501 ATP binding protein MinD CLOST_0849 65388f506f1d37756e6659fcd13b94ee 76 SUPERFAMILY SSF52833 3 74 9.81E-20 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_0849 65388f506f1d37756e6659fcd13b94ee 76 Pfam PF00462 Glutaredoxin 4 62 1.0E-16 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CLOST_0849 65388f506f1d37756e6659fcd13b94ee 76 Gene3D G3DSA:3.40.30.10 1 76 2.2E-25 T 13-10-2018 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 8 530 3.1E-216 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 Pfam PF16658 Class II release factor RF3, C-terminal domain 390 518 3.4E-48 T 13-10-2018 IPR032090 Peptide chain release factor 3, C-terminal CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 SUPERFAMILY SSF54980 396 469 3.96E-15 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 Pfam PF00009 Elongation factor Tu GTP binding domain 14 276 9.3E-51 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 Gene3D G3DSA:3.40.50.300 112 277 9.0E-106 T 13-10-2018 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 Pfam PF03144 Elongation factor Tu domain 2 316 382 7.1E-8 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 SUPERFAMILY SSF50447 263 391 1.93E-27 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 Gene3D G3DSA:3.30.70.3280 393 532 8.2E-45 T 13-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 Gene3D G3DSA:3.40.50.300 74 381 9.0E-106 T 13-10-2018 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 150 5.2E-24 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.3E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 PRINTS PR00315 GTP-binding elongation factor signature 67 75 1.3E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 PRINTS PR00315 GTP-binding elongation factor signature 87 97 1.3E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 PRINTS PR00315 GTP-binding elongation factor signature 103 114 1.3E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 PRINTS PR00315 GTP-binding elongation factor signature 17 30 1.3E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 SUPERFAMILY SSF52540 11 277 2.62E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0654 f1791d90102705c06f7d3c6d32834da0 534 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 6 531 50.348 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CLOST_0191 67068fab0e98a6a1190edc144d6331f1 339 PIRSF PIRSF019169 5 336 3.2E-71 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM CLOST_0191 67068fab0e98a6a1190edc144d6331f1 339 SUPERFAMILY SSF53067 79 177 5.96E-6 T 13-10-2018 CLOST_0191 67068fab0e98a6a1190edc144d6331f1 339 Pfam PF11104 Type IV pilus assembly protein PilM; 22 235 2.9E-21 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM CLOST_0191 67068fab0e98a6a1190edc144d6331f1 339 Pfam PF11104 Type IV pilus assembly protein PilM; 260 323 1.2E-6 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM CLOST_0191 67068fab0e98a6a1190edc144d6331f1 339 Gene3D G3DSA:3.30.420.40 197 309 9.2E-45 T 13-10-2018 CLOST_0191 67068fab0e98a6a1190edc144d6331f1 339 Gene3D G3DSA:3.30.420.40 21 319 9.2E-45 T 13-10-2018 CLOST_0191 67068fab0e98a6a1190edc144d6331f1 339 Gene3D G3DSA:3.30.1490.300 95 154 9.2E-45 T 13-10-2018 CLOST_0191 67068fab0e98a6a1190edc144d6331f1 339 SUPERFAMILY SSF53067 19 311 2.83E-9 T 13-10-2018 CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 Pfam PF07568 Histidine kinase 279 349 2.1E-25 T 13-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 Pfam PF13581 Histidine kinase-like ATPase domain 369 434 6.3E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 SUPERFAMILY SSF55785 170 270 7.33E-7 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 SMART SM00911 279 368 0.0058 T 13-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 Gene3D G3DSA:3.30.450.20 132 264 3.2E-17 T 13-10-2018 CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 SMART SM00387 374 471 0.0014 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 Gene3D G3DSA:3.30.565.10 336 471 3.1E-24 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 SUPERFAMILY SSF55874 336 466 4.6E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0245 feb98d77df519a6f481212bf8753c7c1 472 Pfam PF12282 Signal transduction histidine kinase 3 143 1.1E-25 T 13-10-2018 IPR022066 Signal transduction histidine kinase, N-terminal CLOST_2287 4853b5c61984b29fdf2f88157933d280 388 SMART SM00341 312 388 1.5E-6 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CLOST_2287 4853b5c61984b29fdf2f88157933d280 388 SUPERFAMILY SSF47819 318 385 6.54E-16 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 CLOST_2287 4853b5c61984b29fdf2f88157933d280 388 Pfam PF00570 HRDC domain 318 382 1.8E-17 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CLOST_2287 4853b5c61984b29fdf2f88157933d280 388 Gene3D G3DSA:1.10.150.80 308 387 3.9E-20 T 13-10-2018 CLOST_2287 4853b5c61984b29fdf2f88157933d280 388 Pfam PF08378 Nuclease-related domain 52 178 1.8E-18 T 13-10-2018 IPR011528 Nuclease-related domain, NERD CLOST_1473 dd902c14143502c0da134a828fd10c78 382 Gene3D G3DSA:3.40.50.920 268 379 3.2E-24 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1473 dd902c14143502c0da134a828fd10c78 382 Gene3D G3DSA:3.40.50.970 1 194 1.6E-74 T 13-10-2018 CLOST_1473 dd902c14143502c0da134a828fd10c78 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 245 6.9E-70 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CLOST_1473 dd902c14143502c0da134a828fd10c78 382 SUPERFAMILY SSF52518 4 259 8.83E-71 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1473 dd902c14143502c0da134a828fd10c78 382 SUPERFAMILY SSF52922 267 377 2.49E-22 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1473 dd902c14143502c0da134a828fd10c78 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 275 369 4.4E-24 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Pfam PF02436 Conserved carboxylase domain 823 1023 4.0E-71 T 13-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Gene3D G3DSA:1.10.10.2790 938 973 4.3E-271 T 13-10-2018 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Pfam PF00364 Biotin-requiring enzyme 1076 1141 1.7E-15 T 13-10-2018 IPR000089 Biotin/lipoyl attachment CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 325 2.8E-80 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Gene3D G3DSA:3.10.600.10 506 1055 4.3E-271 T 13-10-2018 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 289 296 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Pfam PF00682 HMGL-like 529 801 2.4E-32 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Gene3D G3DSA:3.30.470.130 1 460 2.2E-194 T 13-10-2018 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 SUPERFAMILY SSF52440 2 115 1.29E-44 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 SUPERFAMILY SSF89000 828 1004 3.81E-55 T 13-10-2018 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 113 1.6E-42 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 SMART SM00878 345 452 1.4E-43 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Gene3D G3DSA:1.10.472.90 813 937 4.3E-271 T 13-10-2018 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Gene3D G3DSA:3.20.20.70 508 812 4.3E-271 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Pfam PF02785 Biotin carboxylase C-terminal domain 345 452 5.8E-28 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 SUPERFAMILY SSF51569 520 831 4.21E-82 T 13-10-2018 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 SUPERFAMILY SSF56059 86 356 3.54E-70 T 13-10-2018 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 SUPERFAMILY SSF51230 1063 1142 1.28E-20 T 13-10-2018 IPR011053 Single hybrid motif CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 Gene3D G3DSA:2.40.50.100 1066 1143 3.9E-21 T 13-10-2018 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 SUPERFAMILY SSF51246 339 457 9.42E-33 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 PIRSF PIRSF001594 1 1143 0.0 T 13-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CLOST_0021 54fbea12a9d9da83d64f6ce5b13cc4c7 1144 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 6 1142 0.0 T 13-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CLOST_1809 30aa7e35d152dcbd179f6559c5088ec3 300 SUPERFAMILY SSF55729 6 138 4.24E-32 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1809 30aa7e35d152dcbd179f6559c5088ec3 300 Gene3D G3DSA:3.40.630.30 8 295 1.2E-94 T 13-10-2018 CLOST_1809 30aa7e35d152dcbd179f6559c5088ec3 300 SUPERFAMILY SSF55729 139 298 7.63E-52 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1809 30aa7e35d152dcbd179f6559c5088ec3 300 PIRSF PIRSF018688 3 300 1.7E-82 T 13-10-2018 IPR016732 Uncharacterised conserved protein UCP018688 CLOST_1809 30aa7e35d152dcbd179f6559c5088ec3 300 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 26 297 8.8E-34 T 13-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CLOST_1809 30aa7e35d152dcbd179f6559c5088ec3 300 Gene3D G3DSA:3.40.630.30 126 293 1.2E-94 T 13-10-2018 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 PRINTS PR00207 Flagellin signature 35 52 4.1E-26 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 PRINTS PR00207 Flagellin signature 74 93 4.1E-26 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 PRINTS PR00207 Flagellin signature 109 132 4.1E-26 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 Gene3D G3DSA:1.10.8.410 239 287 7.2E-25 T 13-10-2018 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 SUPERFAMILY SSF64518 1 286 9.15E-88 T 13-10-2018 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 Gene3D G3DSA:1.20.1330.10 195 238 4.4E-17 T 13-10-2018 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 Gene3D G3DSA:1.20.1330.10 42 182 1.6E-54 T 13-10-2018 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 Pfam PF00700 Bacterial flagellin C-terminal helical region 204 286 9.0E-28 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOST_2306 5c9f8aa1b9c816825e5c1d2d2f16bed5 288 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 6.3E-43 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOST_0861 9e825c98790f52d43be03c0e15a61e33 351 SUPERFAMILY SSF52540 5 338 2.44E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0861 9e825c98790f52d43be03c0e15a61e33 351 Gene3D G3DSA:3.40.50.300 104 351 2.8E-94 T 13-10-2018 CLOST_0861 9e825c98790f52d43be03c0e15a61e33 351 SMART SM00382 124 292 3.2E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0861 9e825c98790f52d43be03c0e15a61e33 351 Gene3D G3DSA:3.30.450.90 1 101 3.1E-28 T 13-10-2018 CLOST_0861 9e825c98790f52d43be03c0e15a61e33 351 Pfam PF00437 Type II/IV secretion system protein 73 267 1.9E-42 T 13-10-2018 IPR001482 Type II/IV secretion system protein CLOST_0861 9e825c98790f52d43be03c0e15a61e33 351 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 195 209 - T 13-10-2018 IPR001482 Type II/IV secretion system protein CLOST_0861 9e825c98790f52d43be03c0e15a61e33 351 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 344 6.9E-133 T 13-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 453 36.969 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 Pfam PF01225 Mur ligase family, catalytic domain 2 101 9.1E-25 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 2 447 4.9E-145 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 Gene3D G3DSA:3.90.190.20 305 453 1.2E-53 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 Pfam PF08245 Mur ligase middle domain 107 286 2.3E-29 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 SUPERFAMILY SSF53244 306 448 2.9E-40 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 SUPERFAMILY SSF53623 87 304 5.49E-57 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 Gene3D G3DSA:3.40.1190.10 90 304 2.5E-64 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 Gene3D G3DSA:3.40.50.720 2 89 2.0E-30 T 13-10-2018 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 SUPERFAMILY SSF51984 1 88 1.7E-26 T 13-10-2018 CLOST_0469 a796fe2e5110facc633b743b0c0a4f46 453 Pfam PF02875 Mur ligase family, glutamate ligase domain 307 389 4.0E-19 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 7.0E-31 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 Gene3D G3DSA:2.40.50.140 2 65 9.8E-31 T 13-10-2018 CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 SMART SM00357 3 66 2.2E-29 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 13-10-2018 IPR019844 Cold-shock conserved site CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 PRINTS PR00050 Cold shock protein signature 24 33 1.6E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 PRINTS PR00050 Cold shock protein signature 39 57 1.6E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 SUPERFAMILY SSF50249 3 65 2.11E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_0865 fc628dbc61e2314f688e7ff6d7f51109 66 PIRSF PIRSF002599 1 66 3.6E-25 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 CLOST_1262 cceab06e684f676366af5541ee3139fa 1009 Gene3D G3DSA:3.40.50.300 632 745 1.7E-19 T 13-10-2018 CLOST_1262 cceab06e684f676366af5541ee3139fa 1009 Gene3D G3DSA:3.90.1570.50 97 266 2.6E-7 T 13-10-2018 CLOST_1262 cceab06e684f676366af5541ee3139fa 1009 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 48 188 1.5E-11 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CLOST_1262 cceab06e684f676366af5541ee3139fa 1009 Pfam PF04851 Type III restriction enzyme, res subunit 284 489 5.4E-14 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CLOST_1262 cceab06e684f676366af5541ee3139fa 1009 SMART SM00487 279 511 2.1E-14 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_1262 cceab06e684f676366af5541ee3139fa 1009 Gene3D G3DSA:3.40.50.300 283 444 9.7E-26 T 13-10-2018 CLOST_1262 cceab06e684f676366af5541ee3139fa 1009 SUPERFAMILY SSF52540 282 536 2.05E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0840 3ed1953095af5f741a25568c84baa323 173 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 110 172 1.1E-15 T 13-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 CLOST_0840 3ed1953095af5f741a25568c84baa323 173 Gene3D G3DSA:1.10.1660.10 4 55 4.7E-8 T 13-10-2018 CLOST_0840 3ed1953095af5f741a25568c84baa323 173 Pfam PF12728 Helix-turn-helix domain 6 54 1.1E-12 T 13-10-2018 CLOST_0840 3ed1953095af5f741a25568c84baa323 173 Gene3D G3DSA:2.40.50.100 97 167 4.3E-26 T 13-10-2018 CLOST_0840 3ed1953095af5f741a25568c84baa323 173 Gene3D G3DSA:2.40.50.140 60 170 4.3E-26 T 13-10-2018 CLOST_0840 3ed1953095af5f741a25568c84baa323 173 SUPERFAMILY SSF50331 59 171 2.13E-19 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CLOST_0840 3ed1953095af5f741a25568c84baa323 173 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 54 1.1E-15 T 13-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CLOST_2489 e4f5afab962fdc333b7cdfe4f6020ffe 244 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2489 e4f5afab962fdc333b7cdfe4f6020ffe 244 Pfam PF00005 ABC transporter 20 158 4.7E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2489 e4f5afab962fdc333b7cdfe4f6020ffe 244 Gene3D G3DSA:3.40.50.300 1 233 8.8E-58 T 13-10-2018 CLOST_2489 e4f5afab962fdc333b7cdfe4f6020ffe 244 SUPERFAMILY SSF52540 3 219 1.78E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2489 e4f5afab962fdc333b7cdfe4f6020ffe 244 SMART SM00382 29 206 6.7E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 Pfam PF11907 Domain of unknown function (DUF3427) 828 1026 3.8E-28 T 13-10-2018 IPR021835 Protein of unknown function DUF3427 CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 Pfam PF13091 PLD-like domain 141 274 1.6E-13 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 Gene3D G3DSA:3.40.50.300 487 677 1.9E-32 T 13-10-2018 CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 Pfam PF00271 Helicase conserved C-terminal domain 554 646 4.8E-9 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 SUPERFAMILY SSF52540 367 667 5.41E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 Pfam PF04851 Type III restriction enzyme, res subunit 315 468 8.6E-31 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 SUPERFAMILY SSF56024 132 277 1.65E-9 T 13-10-2018 CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 Gene3D G3DSA:3.30.870.10 131 298 8.2E-30 T 13-10-2018 CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 SMART SM00487 311 495 2.6E-11 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 SMART SM00490 567 648 1.5E-9 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1046 b2e98f86826c7de15cfb15c8ce3ce255 1034 Gene3D G3DSA:3.40.50.300 299 483 6.2E-41 T 13-10-2018 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 Pfam PF07687 Peptidase dimerisation domain 207 293 2.4E-8 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 Gene3D G3DSA:3.40.630.10 2 227 8.2E-59 T 13-10-2018 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PIRSF PIRSF016599 1 487 8.9E-185 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 8 484 1.9E-182 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 SUPERFAMILY SSF53187 11 484 2.27E-58 T 13-10-2018 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 Pfam PF01546 Peptidase family M20/M25/M40 72 482 8.5E-20 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 Gene3D G3DSA:3.40.630.10 332 487 2.6E-25 T 13-10-2018 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PRINTS PR00934 X-His dipeptidase (M25) signature 452 474 3.4E-55 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PRINTS PR00934 X-His dipeptidase (M25) signature 159 177 3.4E-55 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PRINTS PR00934 X-His dipeptidase (M25) signature 101 119 3.4E-55 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PRINTS PR00934 X-His dipeptidase (M25) signature 430 446 3.4E-55 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PRINTS PR00934 X-His dipeptidase (M25) signature 135 152 3.4E-55 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PRINTS PR00934 X-His dipeptidase (M25) signature 206 223 3.4E-55 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PRINTS PR00934 X-His dipeptidase (M25) signature 252 271 3.4E-55 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1912 d149d930f4059583513f9f0c7d6fef7f 489 PRINTS PR00934 X-His dipeptidase (M25) signature 80 99 3.4E-55 T 13-10-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Gene3D G3DSA:3.30.70.870 289 370 3.8E-36 T 13-10-2018 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 SUPERFAMILY SSF50447 169 291 1.26E-32 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CLOST_1803 105157385619477e9a27314f98b6f2e5 600 SUPERFAMILY SSF52540 4 208 4.1E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1803 105157385619477e9a27314f98b6f2e5 600 PRINTS PR00315 GTP-binding elongation factor signature 93 104 2.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 PRINTS PR00315 GTP-binding elongation factor signature 129 138 2.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 PRINTS PR00315 GTP-binding elongation factor signature 77 87 2.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 PRINTS PR00315 GTP-binding elongation factor signature 52 60 2.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 SMART SM00838 401 489 4.7E-6 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Hamap MF_00071 Elongation factor 4 [lepA]. 1 600 302.927 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 TIGRFAM TIGR01393 lepA: elongation factor 4 6 599 0.0 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 7.8E-53 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Pfam PF00679 Elongation factor G C-terminus 402 489 1.5E-26 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Pfam PF06421 GTP-binding protein LepA C-terminus 491 597 2.4E-51 T 13-10-2018 IPR013842 GTP-binding protein LepA, C-terminal CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Gene3D G3DSA:3.40.50.300 3 188 2.0E-72 T 13-10-2018 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Pfam PF03144 Elongation factor Tu domain 2 208 278 1.1E-13 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site CLOST_1803 105157385619477e9a27314f98b6f2e5 600 SUPERFAMILY SSF54980 402 497 2.21E-27 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_1803 105157385619477e9a27314f98b6f2e5 600 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 178 4.3E-21 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Gene3D G3DSA:2.40.30.10 189 288 6.9E-38 T 13-10-2018 CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Gene3D G3DSA:3.30.70.2570 483 557 2.3E-34 T 13-10-2018 IPR038363 LepA, C-terminal domain superfamily CLOST_1803 105157385619477e9a27314f98b6f2e5 600 SUPERFAMILY SSF54980 295 373 2.01E-17 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_1803 105157385619477e9a27314f98b6f2e5 600 Gene3D G3DSA:3.30.70.3380 371 482 1.2E-40 T 13-10-2018 CLOST_1102 317e96368d469d6ccd7c7ef12ab790e3 258 Pfam PF02654 Cobalamin-5-phosphate synthase 8 244 8.3E-53 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 CLOST_1102 317e96368d469d6ccd7c7ef12ab790e3 258 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 3 244 2.9E-40 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 CLOST_1102 317e96368d469d6ccd7c7ef12ab790e3 258 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 258 33.477 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 CLOST_2352 6a438896cafa4d00481268b2b43877b1 97 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 14 88 5.0E-15 T 13-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CLOST_2352 6a438896cafa4d00481268b2b43877b1 97 SUPERFAMILY SSF101498 11 89 7.06E-14 T 13-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily CLOST_2352 6a438896cafa4d00481268b2b43877b1 97 Pfam PF04316 Anti-sigma-28 factor, FlgM 37 87 1.2E-15 T 13-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 28 42 1.2E-10 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 173 185 1.2E-10 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 7 23 1.2E-10 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 48 61 1.2E-10 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 Gene3D G3DSA:1.10.1020.10 55 153 4.3E-35 T 13-10-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 7 222 2.2E-23 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 PIRSF PIRSF000398 1 261 2.6E-46 T 13-10-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 Gene3D G3DSA:3.40.50.150 4 228 4.3E-35 T 13-10-2018 CLOST_1547 889dcda751cf32386b4d2db3d9483b2d 269 SUPERFAMILY SSF53335 2 257 1.53E-45 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0064 fcbe3e47f961133d2e8926c80f1465e0 636 SMART SM00490 307 388 8.9E-7 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0064 fcbe3e47f961133d2e8926c80f1465e0 636 Pfam PF00271 Helicase conserved C-terminal domain 291 386 4.4E-9 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0064 fcbe3e47f961133d2e8926c80f1465e0 636 Pfam PF04851 Type III restriction enzyme, res subunit 22 193 9.5E-24 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CLOST_0064 fcbe3e47f961133d2e8926c80f1465e0 636 Gene3D G3DSA:3.40.50.300 211 413 1.9E-22 T 13-10-2018 CLOST_0064 fcbe3e47f961133d2e8926c80f1465e0 636 Gene3D G3DSA:3.40.50.300 13 210 1.8E-22 T 13-10-2018 CLOST_0064 fcbe3e47f961133d2e8926c80f1465e0 636 SMART SM00487 19 222 1.5E-10 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_0064 fcbe3e47f961133d2e8926c80f1465e0 636 SUPERFAMILY SSF52540 42 392 2.12E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0880 45be40814601b069d87065e83b5af1e4 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 273 322 7.8E-10 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0880 45be40814601b069d87065e83b5af1e4 343 Gene3D G3DSA:3.40.50.300 37 343 1.4E-58 T 13-10-2018 CLOST_0880 45be40814601b069d87065e83b5af1e4 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 274 339 4.2E-13 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0880 45be40814601b069d87065e83b5af1e4 343 SMART SM00382 73 258 8.3E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0880 45be40814601b069d87065e83b5af1e4 343 Pfam PF00005 ABC transporter 65 209 1.8E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0880 45be40814601b069d87065e83b5af1e4 343 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0880 45be40814601b069d87065e83b5af1e4 343 SUPERFAMILY SSF52540 39 264 4.21E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 PIRSF PIRSF039101 1 506 1.6E-197 T 13-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 Pfam PF01336 OB-fold nucleic acid binding domain 61 137 3.2E-14 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 Gene3D G3DSA:3.30.930.10 150 506 3.2E-130 T 13-10-2018 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 Gene3D G3DSA:2.40.50.140 5 149 9.6E-39 T 13-10-2018 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 SUPERFAMILY SSF50249 11 147 8.36E-38 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 19 496 43.907 T 13-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 SUPERFAMILY SSF55681 154 493 8.76E-116 T 13-10-2018 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 377 393 9.6E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 191 201 9.6E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 254 271 9.6E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 207 223 9.6E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 PRINTS PR00982 Lysyl-tRNA synthetase signature 236 249 9.6E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 13 494 1.3E-202 T 13-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_0952 a422572d1f93e6c36172a4a834329f30 506 Pfam PF00152 tRNA synthetases class II (D, K and N) 155 492 4.7E-79 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 Gene3D G3DSA:1.10.8.260 266 323 5.7E-115 T 13-10-2018 IPR023166 HI0933-like insert domain superfamily CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 4 392 2.6E-123 T 13-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.2E-6 T 13-10-2018 CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 348 370 5.2E-6 T 13-10-2018 CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 SUPERFAMILY SSF51905 2 393 4.52E-43 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 SUPERFAMILY SSF160996 190 341 7.32E-32 T 13-10-2018 CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 Pfam PF03486 HI0933-like protein 3 392 3.9E-117 T 13-10-2018 CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 Gene3D G3DSA:2.40.30.10 189 340 5.7E-115 T 13-10-2018 CLOST_1450 7155d3b462d1661eb09d3842f4314eec 397 Gene3D G3DSA:3.50.50.60 5 389 5.7E-115 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1753 4a87ea4a31409dabbad08b0204f3f24d 261 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 10 243 1.0E-75 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CLOST_1753 4a87ea4a31409dabbad08b0204f3f24d 261 Gene3D G3DSA:3.40.1390.30 10 234 4.3E-74 T 13-10-2018 CLOST_1753 4a87ea4a31409dabbad08b0204f3f24d 261 SUPERFAMILY SSF102705 1 259 1.44E-82 T 13-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily CLOST_1753 4a87ea4a31409dabbad08b0204f3f24d 261 Gene3D G3DSA:3.40.1390.30 100 222 4.3E-74 T 13-10-2018 CLOST_1753 4a87ea4a31409dabbad08b0204f3f24d 261 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 252 7.5E-65 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 PIRSF PIRSF000676 1 298 8.3E-78 T 13-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 Pfam PF00288 GHMP kinases N terminal domain 81 138 8.8E-9 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 PRINTS PR00958 Homoserine kinase signature 91 106 4.8E-33 T 13-10-2018 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 PRINTS PR00958 Homoserine kinase signature 164 181 4.8E-33 T 13-10-2018 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 PRINTS PR00958 Homoserine kinase signature 243 258 4.8E-33 T 13-10-2018 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 PRINTS PR00958 Homoserine kinase signature 9 24 4.8E-33 T 13-10-2018 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 PRINTS PR00958 Homoserine kinase signature 125 138 4.8E-33 T 13-10-2018 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 TIGRFAM TIGR00191 thrB: homoserine kinase 2 295 4.7E-74 T 13-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 Gene3D G3DSA:3.30.70.890 157 261 1.7E-78 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 SUPERFAMILY SSF54211 1 149 5.01E-27 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 Gene3D G3DSA:3.30.230.10 4 156 1.7E-78 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 Hamap MF_00384 Homoserine kinase [thrB]. 4 296 26.952 T 13-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 SUPERFAMILY SSF55060 161 264 3.13E-24 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CLOST_2395 1ba2cd06074db8155a45f72c675f99fc 298 Pfam PF08544 GHMP kinases C terminal 200 261 2.1E-4 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain CLOST_0845 97e955bf0b8bbef0a18cfb50296f99e2 398 SUPERFAMILY SSF52540 11 177 1.59E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0845 97e955bf0b8bbef0a18cfb50296f99e2 398 Gene3D G3DSA:3.40.50.300 2 175 4.3E-33 T 13-10-2018 CLOST_0845 97e955bf0b8bbef0a18cfb50296f99e2 398 Gene3D G3DSA:3.40.50.11420 178 285 9.9E-42 T 13-10-2018 CLOST_0845 97e955bf0b8bbef0a18cfb50296f99e2 398 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 144 1.5E-17 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_0845 97e955bf0b8bbef0a18cfb50296f99e2 398 Gene3D G3DSA:3.40.50.11410 286 394 6.4E-37 T 13-10-2018 CLOST_0845 97e955bf0b8bbef0a18cfb50296f99e2 398 Pfam PF01926 50S ribosome-binding GTPase 12 126 1.7E-16 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_0845 97e955bf0b8bbef0a18cfb50296f99e2 398 TIGRFAM TIGR03918 GTP_HydF: [FeFe] hydrogenase H-cluster maturation GTPase HydF 3 390 5.3E-158 T 13-10-2018 IPR023873 [FeFe]-hydrogenase H-cluster maturation GTPase HydF CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 PIRSF PIRSF000148 3 327 1.4E-122 T 13-10-2018 CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 SUPERFAMILY SSF55347 129 314 1.76E-70 T 13-10-2018 CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 SMART SM00859 5 121 3.8E-42 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 3 327 35.44 T 13-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 Gene3D G3DSA:3.30.360.10 128 310 3.1E-130 T 13-10-2018 CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 119 2.1E-33 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 Gene3D G3DSA:3.40.50.720 6 324 3.1E-130 T 13-10-2018 CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 SUPERFAMILY SSF51735 4 157 5.59E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 313 5.8E-43 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CLOST_0016 b16c3005090448f5a086fdeedd2fb038 327 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 326 1.8E-136 T 13-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 CLOST_0506 7c70b90c7a2aa2b1fd1b7b32c966fee3 451 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 16 442 1.1E-199 T 13-10-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CLOST_0506 7c70b90c7a2aa2b1fd1b7b32c966fee3 451 Gene3D G3DSA:3.40.50.1100 120 242 3.1E-185 T 13-10-2018 CLOST_0506 7c70b90c7a2aa2b1fd1b7b32c966fee3 451 Gene3D G3DSA:3.40.50.1100 28 442 3.1E-185 T 13-10-2018 CLOST_0506 7c70b90c7a2aa2b1fd1b7b32c966fee3 451 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 102 403 1.1E-53 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_0506 7c70b90c7a2aa2b1fd1b7b32c966fee3 451 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 112 126 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CLOST_0506 7c70b90c7a2aa2b1fd1b7b32c966fee3 451 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 451 226.024 T 13-10-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CLOST_0506 7c70b90c7a2aa2b1fd1b7b32c966fee3 451 SUPERFAMILY SSF53686 62 439 4.53E-52 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_1110 c014af17e2a0d4344c8b67319a3c3622 430 PIRSF PIRSF011588 1 430 1.7E-224 T 13-10-2018 IPR016585 Glycine/sarcosine/betaine reductase, component B, fused alpha/beta GO:0050485|GO:0055114 CLOST_1110 c014af17e2a0d4344c8b67319a3c3622 430 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 1 428 3.1E-213 T 13-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CLOST_1922 dde4405873af474d1073534d51ce1994 220 SUPERFAMILY SSF55811 30 198 4.6E-26 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 CLOST_1922 dde4405873af474d1073534d51ce1994 220 Pfam PF00293 NUDIX domain 28 139 2.2E-9 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CLOST_1922 dde4405873af474d1073534d51ce1994 220 Gene3D G3DSA:3.90.79.10 3 206 6.5E-44 T 13-10-2018 CLOST_0586 fa4ff68977412e6b0242a9bb04562369 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 38 141 1.1E-15 T 13-10-2018 IPR016188 PurM-like, N-terminal domain CLOST_0586 fa4ff68977412e6b0242a9bb04562369 330 Gene3D G3DSA:3.30.1330.10 3 146 7.1E-30 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_0586 fa4ff68977412e6b0242a9bb04562369 330 SUPERFAMILY SSF55326 18 141 4.54E-23 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_0586 fa4ff68977412e6b0242a9bb04562369 330 SUPERFAMILY SSF56042 154 315 4.49E-24 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_0586 fa4ff68977412e6b0242a9bb04562369 330 PIRSF PIRSF005644 1 330 1.8E-63 T 13-10-2018 IPR011854 Carbamoyl dehydratase HypE CLOST_0586 fa4ff68977412e6b0242a9bb04562369 330 Gene3D G3DSA:3.90.650.10 153 330 1.0E-33 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_0586 fa4ff68977412e6b0242a9bb04562369 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 307 3.8E-12 T 13-10-2018 IPR010918 PurM-like, C-terminal domain CLOST_0087 c8a3ee268e3274dfc565ac316023768b 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 466 4.2E-69 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain CLOST_0087 c8a3ee268e3274dfc565ac316023768b 547 Gene3D G3DSA:3.10.105.10 307 518 2.6E-30 T 13-10-2018 CLOST_0087 c8a3ee268e3274dfc565ac316023768b 547 PIRSF PIRSF002741 6 547 6.2E-75 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CLOST_0087 c8a3ee268e3274dfc565ac316023768b 547 Gene3D G3DSA:3.40.190.10 24 306 7.1E-61 T 13-10-2018 CLOST_0087 c8a3ee268e3274dfc565ac316023768b 547 SUPERFAMILY SSF53850 50 545 3.67E-100 T 13-10-2018 CLOST_2139 ac04e6d06a206fcf7602b0ef287a4ce2 331 PIRSF PIRSF004532 1 323 2.7E-145 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CLOST_2139 ac04e6d06a206fcf7602b0ef287a4ce2 331 Gene3D G3DSA:3.40.190.90 122 286 8.9E-133 T 13-10-2018 CLOST_2139 ac04e6d06a206fcf7602b0ef287a4ce2 331 Gene3D G3DSA:3.30.540.10 7 313 8.9E-133 T 13-10-2018 CLOST_2139 ac04e6d06a206fcf7602b0ef287a4ce2 331 SUPERFAMILY SSF56655 1 317 3.24E-106 T 13-10-2018 CLOST_2139 ac04e6d06a206fcf7602b0ef287a4ce2 331 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 313 1.1E-141 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CLOST_2139 ac04e6d06a206fcf7602b0ef287a4ce2 331 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 321 1.0E-127 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 SUPERFAMILY SSF52540 3 868 1.9E-111 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 1 1183 16.617 T 13-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1023 1174 6.8E-9 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 3 1182 0.0 T 13-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Gene3D G3DSA:3.40.50.300 739 936 4.6E-39 T 13-10-2018 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Gene3D G3DSA:3.40.50.300 459 738 3.5E-34 T 13-10-2018 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 SUPERFAMILY SSF52980 1013 1177 2.31E-29 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 445 2.8E-74 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Gene3D G3DSA:3.40.50.300 283 458 4.7E-28 T 13-10-2018 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Gene3D G3DSA:3.40.50.300 1 183 1.2E-37 T 13-10-2018 CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Gene3D G3DSA:3.90.320.10 971 1183 2.7E-54 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal CLOST_0225 32d5bbbb32c1ccf6a41be0883c197cd2 1184 Pfam PF13361 UvrD-like helicase C-terminal domain 456 863 1.4E-30 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CLOST_1845 cdbdae7cd5c32ce36ddff7ff2f61f99c 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 1.3E-26 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1845 cdbdae7cd5c32ce36ddff7ff2f61f99c 63 SUPERFAMILY SSF143800 1 62 4.51E-27 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1845 cdbdae7cd5c32ce36ddff7ff2f61f99c 63 Pfam PF00830 Ribosomal L28 family 3 58 1.3E-25 T 13-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1845 cdbdae7cd5c32ce36ddff7ff2f61f99c 63 Gene3D G3DSA:2.30.170.40 19 63 6.0E-22 T 13-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1845 cdbdae7cd5c32ce36ddff7ff2f61f99c 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.633 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1980 04d1f4ed7bb7d98ad2bd5060e8725123 152 Gene3D G3DSA:1.10.10.10 70 152 2.4E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1980 04d1f4ed7bb7d98ad2bd5060e8725123 152 SUPERFAMILY SSF53155 5 76 4.51E-15 T 13-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CLOST_1980 04d1f4ed7bb7d98ad2bd5060e8725123 152 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 72 151 3.0E-30 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CLOST_1980 04d1f4ed7bb7d98ad2bd5060e8725123 152 SUPERFAMILY SSF46767 70 151 2.22E-30 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 CLOST_1980 04d1f4ed7bb7d98ad2bd5060e8725123 152 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 71 150 1.9E-32 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CLOST_1980 04d1f4ed7bb7d98ad2bd5060e8725123 152 Gene3D G3DSA:3.30.160.70 1 67 4.4E-13 T 13-10-2018 CLOST_1980 04d1f4ed7bb7d98ad2bd5060e8725123 152 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 151 40.176 T 13-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CLOST_1980 04d1f4ed7bb7d98ad2bd5060e8725123 152 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 121 127 - T 13-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CLOST_1302 3362cc51f510d2b60db32f1dca348c9a 471 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 69 465 8.9E-154 T 13-10-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ CLOST_1302 3362cc51f510d2b60db32f1dca348c9a 471 SMART SM00729 147 371 2.8E-46 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1302 3362cc51f510d2b60db32f1dca348c9a 471 Gene3D G3DSA:3.80.30.20 103 467 2.1E-74 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1302 3362cc51f510d2b60db32f1dca348c9a 471 Pfam PF04055 Radical SAM superfamily 153 326 7.4E-16 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1302 3362cc51f510d2b60db32f1dca348c9a 471 SUPERFAMILY SSF102114 140 458 2.09E-67 T 13-10-2018 CLOST_0198 6214c78e9eb7a00e3555ebb4d3466304 277 Pfam PF05853 beta-keto acid cleavage enzyme 7 276 1.1E-104 T 13-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 CLOST_0198 6214c78e9eb7a00e3555ebb4d3466304 277 Gene3D G3DSA:3.20.20.70 2 277 3.1E-107 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1965 9c9b384a8260913c7d99421f693351de 326 SMART SM00829 10 323 1.8E-36 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CLOST_1965 9c9b384a8260913c7d99421f693351de 326 Gene3D G3DSA:3.90.180.10 8 321 7.9E-102 T 13-10-2018 CLOST_1965 9c9b384a8260913c7d99421f693351de 326 SUPERFAMILY SSF51735 118 294 1.23E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1965 9c9b384a8260913c7d99421f693351de 326 Gene3D G3DSA:3.40.50.720 126 293 7.9E-102 T 13-10-2018 CLOST_1965 9c9b384a8260913c7d99421f693351de 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 94 4.5E-8 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CLOST_1965 9c9b384a8260913c7d99421f693351de 326 SUPERFAMILY SSF50129 1 150 4.87E-40 T 13-10-2018 IPR011032 GroES-like superfamily CLOST_1965 9c9b384a8260913c7d99421f693351de 326 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 146 167 - T 13-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CLOST_1965 9c9b384a8260913c7d99421f693351de 326 Pfam PF00107 Zinc-binding dehydrogenase 157 279 1.3E-22 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CLOST_1073 f6cda7b41d35b86b08ea9e612ec108c6 233 SMART SM00862 155 230 2.0E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1073 f6cda7b41d35b86b08ea9e612ec108c6 233 SUPERFAMILY SSF46894 130 231 2.18E-25 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_1073 f6cda7b41d35b86b08ea9e612ec108c6 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 1.1E-22 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1073 f6cda7b41d35b86b08ea9e612ec108c6 233 Gene3D G3DSA:3.40.50.2300 2 132 6.2E-37 T 13-10-2018 CLOST_1073 f6cda7b41d35b86b08ea9e612ec108c6 233 Gene3D G3DSA:1.10.10.10 133 233 4.0E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1073 f6cda7b41d35b86b08ea9e612ec108c6 233 SMART SM00448 4 114 3.2E-41 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1073 f6cda7b41d35b86b08ea9e612ec108c6 233 Pfam PF00072 Response regulator receiver domain 6 115 6.2E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1073 f6cda7b41d35b86b08ea9e612ec108c6 233 SUPERFAMILY SSF52172 3 123 1.35E-38 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1786 d5f8811aa07dbd005a7b3e52718fcf9b 150 Gene3D G3DSA:1.10.1510.10 4 93 1.3E-25 T 13-10-2018 CLOST_1786 d5f8811aa07dbd005a7b3e52718fcf9b 150 Pfam PF09424 Yqey-like protein 7 149 1.4E-51 T 13-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 CLOST_1786 d5f8811aa07dbd005a7b3e52718fcf9b 150 SUPERFAMILY SSF89095 4 150 1.99E-41 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 CLOST_1786 d5f8811aa07dbd005a7b3e52718fcf9b 150 Gene3D G3DSA:1.10.10.410 94 149 1.4E-22 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CLOST_2193 74fb84a3f593056bd84a1d3146ecc18f 110 SUPERFAMILY SSF54843 1 110 2.88E-44 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2193 74fb84a3f593056bd84a1d3146ecc18f 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 13-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2193 74fb84a3f593056bd84a1d3146ecc18f 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 3.6E-39 T 13-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CLOST_2193 74fb84a3f593056bd84a1d3146ecc18f 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.5E-43 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2193 74fb84a3f593056bd84a1d3146ecc18f 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.253 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2193 74fb84a3f593056bd84a1d3146ecc18f 110 Gene3D G3DSA:3.90.470.10 1 110 9.7E-47 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_1713 1ef707086775ed435001855005cb45f9 139 Pfam PF01584 CheW-like domain 5 138 1.2E-34 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 CLOST_1713 1ef707086775ed435001855005cb45f9 139 Gene3D G3DSA:2.40.50.180 22 137 6.2E-41 T 13-10-2018 CLOST_1713 1ef707086775ed435001855005cb45f9 139 Gene3D G3DSA:2.30.30.40 7 131 6.2E-41 T 13-10-2018 CLOST_1713 1ef707086775ed435001855005cb45f9 139 SMART SM00260 1 137 1.2E-32 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 CLOST_1713 1ef707086775ed435001855005cb45f9 139 SUPERFAMILY SSF50341 3 138 2.22E-34 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 CLOST_1386 940baa9d87138de7bfc5ef3f7da8f56c 147 PIRSF PIRSF006614 15 147 1.2E-59 T 13-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CLOST_1386 940baa9d87138de7bfc5ef3f7da8f56c 147 Pfam PF02142 MGS-like domain 33 124 5.3E-18 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain CLOST_1386 940baa9d87138de7bfc5ef3f7da8f56c 147 SUPERFAMILY SSF52335 18 145 1.31E-52 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily CLOST_1386 940baa9d87138de7bfc5ef3f7da8f56c 147 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 18 137 33.615 T 13-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CLOST_1386 940baa9d87138de7bfc5ef3f7da8f56c 147 Gene3D G3DSA:3.40.50.1380 14 147 1.1E-54 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily CLOST_1386 940baa9d87138de7bfc5ef3f7da8f56c 147 SMART SM00851 31 124 4.2E-21 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain CLOST_1386 940baa9d87138de7bfc5ef3f7da8f56c 147 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 18 138 1.5E-58 T 13-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CLOST_1386 940baa9d87138de7bfc5ef3f7da8f56c 147 ProSitePatterns PS01335 Methylglyoxal synthase active site. 71 79 - T 13-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CLOST_2061 47474ba78bc01d44d27d450545ed9f6d 347 Pfam PF01966 HD domain 132 254 5.7E-20 T 13-10-2018 IPR006674 HD domain CLOST_2061 47474ba78bc01d44d27d450545ed9f6d 347 TIGRFAM TIGR00277 HDIG: HDIG domain 129 224 5.4E-10 T 13-10-2018 IPR006675 HDIG domain CLOST_2061 47474ba78bc01d44d27d450545ed9f6d 347 SUPERFAMILY SSF109604 119 292 7.19E-38 T 13-10-2018 CLOST_2061 47474ba78bc01d44d27d450545ed9f6d 347 Gene3D G3DSA:1.10.3210.10 9 296 1.9E-75 T 13-10-2018 CLOST_2061 47474ba78bc01d44d27d450545ed9f6d 347 SMART SM00471 128 264 1.1E-12 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_2414 c47a02519188a11c578d04093f4af59c 298 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 293 2.0E-98 T 13-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CLOST_2414 c47a02519188a11c578d04093f4af59c 298 Hamap MF_01987 Ribokinase [rbsK]. 2 295 25.991 T 13-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CLOST_2414 c47a02519188a11c578d04093f4af59c 298 Gene3D G3DSA:3.40.1190.20 1 294 6.5E-96 T 13-10-2018 IPR029056 Ribokinase-like CLOST_2414 c47a02519188a11c578d04093f4af59c 298 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CLOST_2414 c47a02519188a11c578d04093f4af59c 298 SUPERFAMILY SSF53613 1 294 2.18E-77 T 13-10-2018 IPR029056 Ribokinase-like CLOST_2414 c47a02519188a11c578d04093f4af59c 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 240 253 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CLOST_2414 c47a02519188a11c578d04093f4af59c 298 Pfam PF00294 pfkB family carbohydrate kinase 1 288 2.5E-63 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB CLOST_2414 c47a02519188a11c578d04093f4af59c 298 PRINTS PR00990 Ribokinase signature 33 52 6.5E-30 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CLOST_2414 c47a02519188a11c578d04093f4af59c 298 PRINTS PR00990 Ribokinase signature 6 27 6.5E-30 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CLOST_2414 c47a02519188a11c578d04093f4af59c 298 PRINTS PR00990 Ribokinase signature 170 185 6.5E-30 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CLOST_2414 c47a02519188a11c578d04093f4af59c 298 PRINTS PR00990 Ribokinase signature 211 222 6.5E-30 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CLOST_2414 c47a02519188a11c578d04093f4af59c 298 PRINTS PR00990 Ribokinase signature 104 117 6.5E-30 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CLOST_0099 de331b7d1f29e0e7fa99bcad06692d3e 540 Gene3D G3DSA:3.30.450.20 439 534 1.0E-12 T 13-10-2018 CLOST_0099 de331b7d1f29e0e7fa99bcad06692d3e 540 SUPERFAMILY SSF103190 484 539 2.56E-9 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0099 de331b7d1f29e0e7fa99bcad06692d3e 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 210 360 6.5E-36 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0099 de331b7d1f29e0e7fa99bcad06692d3e 540 Gene3D G3DSA:1.10.287.950 80 407 4.3E-57 T 13-10-2018 CLOST_0099 de331b7d1f29e0e7fa99bcad06692d3e 540 SMART SM00283 132 407 1.8E-54 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0099 de331b7d1f29e0e7fa99bcad06692d3e 540 SUPERFAMILY SSF58104 75 406 8.72E-59 T 13-10-2018 CLOST_0252 1f68058ea417a9b3ace027ca881198fd 97 Gene3D G3DSA:3.30.70.1710 1 97 4.7E-41 T 13-10-2018 CLOST_0252 1f68058ea417a9b3ace027ca881198fd 97 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 6 30 2.0E-6 T 13-10-2018 CLOST_0252 1f68058ea417a9b3ace027ca881198fd 97 SUPERFAMILY SSF143414 5 93 3.27E-32 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0252 1f68058ea417a9b3ace027ca881198fd 97 SMART SM00877 5 81 6.2E-37 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0252 1f68058ea417a9b3ace027ca881198fd 97 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 23 42 - T 13-10-2018 IPR020808 Bacterial microcompartments protein, conserved site CLOST_0252 1f68058ea417a9b3ace027ca881198fd 97 Pfam PF00936 BMC domain 6 81 7.2E-29 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_1328 5d999590e0dacd453be35da5251765b9 835 Gene3D G3DSA:3.40.710.10 347 729 1.7E-104 T 13-10-2018 CLOST_1328 5d999590e0dacd453be35da5251765b9 835 Gene3D G3DSA:1.10.3810.10 70 253 1.2E-63 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1328 5d999590e0dacd453be35da5251765b9 835 SUPERFAMILY SSF53955 66 238 5.34E-62 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily CLOST_1328 5d999590e0dacd453be35da5251765b9 835 Pfam PF00912 Transglycosylase 77 237 2.7E-58 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1328 5d999590e0dacd453be35da5251765b9 835 Pfam PF00905 Penicillin binding protein transpeptidase domain 420 702 3.0E-33 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CLOST_1328 5d999590e0dacd453be35da5251765b9 835 SUPERFAMILY SSF56601 304 762 8.55E-102 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 SUPERFAMILY SSF55785 135 230 4.36E-13 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Pfam PF00571 CBS domain 11 63 0.0014 T 13-10-2018 IPR000644 CBS domain CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Pfam PF00571 CBS domain 81 126 6.2E-6 T 13-10-2018 IPR000644 CBS domain CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 SUPERFAMILY SSF52540 272 518 6.48E-71 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 SUPERFAMILY SSF46689 486 581 1.74E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 SMART SM00091 136 202 2.4E-5 T 13-10-2018 IPR000014 PAS domain CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Pfam PF00158 Sigma-54 interaction domain 273 440 6.5E-69 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Gene3D G3DSA:3.10.580.10 2 126 4.9E-17 T 13-10-2018 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 SUPERFAMILY SSF54631 9 129 4.72E-19 T 13-10-2018 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Pfam PF13426 PAS domain 147 238 2.4E-7 T 13-10-2018 IPR000014 PAS domain CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 359 374 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Pfam PF02954 Bacterial regulatory protein, Fis family 539 576 4.4E-12 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 SMART SM00382 293 436 1.6E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Gene3D G3DSA:1.10.8.60 446 513 1.6E-22 T 13-10-2018 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 544 561 1.7E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 561 581 1.7E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Gene3D G3DSA:3.40.50.300 259 444 2.1E-63 T 13-10-2018 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Gene3D G3DSA:3.30.450.20 127 254 1.9E-15 T 13-10-2018 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 486 495 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 297 310 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 SMART SM00116 81 128 6.5E-4 T 13-10-2018 IPR000644 CBS domain CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 SMART SM00116 18 65 88.0 T 13-10-2018 IPR000644 CBS domain CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 133 246 9.7E-9 T 13-10-2018 IPR000014 PAS domain CLOST_2237 7182eb9bd9b12312c1da901626be627a 584 Gene3D G3DSA:1.10.10.60 514 583 1.9E-16 T 13-10-2018 CLOST_2463 5d0d0bf05ff58919fba91a5daafeb908 335 SUPERFAMILY SSF81345 8 329 5.23E-77 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_2463 5d0d0bf05ff58919fba91a5daafeb908 335 Pfam PF01032 FecCD transport family 21 328 2.1E-85 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 CLOST_2463 5d0d0bf05ff58919fba91a5daafeb908 335 Gene3D G3DSA:1.10.3470.10 8 333 9.7E-85 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 SUPERFAMILY SSF51621 249 535 1.49E-100 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 458 473 1.3E-22 T 13-10-2018 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 287 306 1.3E-22 T 13-10-2018 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 441 456 1.3E-22 T 13-10-2018 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 494 506 1.3E-22 T 13-10-2018 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 SUPERFAMILY SSF47831 22 136 5.23E-28 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 Gene3D G3DSA:1.10.274.10 21 141 6.1E-66 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 179 190 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 Gene3D G3DSA:3.50.30.10 4 228 6.1E-66 T 13-10-2018 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 Pfam PF05524 PEP-utilising enzyme, N-terminal 3 121 2.8E-28 T 13-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 441 459 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 Gene3D G3DSA:3.20.20.60 229 564 3.6E-114 T 13-10-2018 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 3 559 1.0E-173 T 13-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 255 533 2.1E-105 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 PIRSF PIRSF000732 1 564 1.7E-194 T 13-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 Pfam PF00391 PEP-utilising enzyme, mobile domain 147 220 4.1E-20 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CLOST_0177 d2cb34eb077271eebef49cf15ebdb721 564 SUPERFAMILY SSF52009 120 239 5.62E-31 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 PRINTS PR00113 Alkaline phosphatase signature 259 288 1.1E-22 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 PRINTS PR00113 Alkaline phosphatase signature 141 161 1.1E-22 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 PRINTS PR00113 Alkaline phosphatase signature 185 195 1.1E-22 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 PRINTS PR00113 Alkaline phosphatase signature 103 118 1.1E-22 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 PRINTS PR00113 Alkaline phosphatase signature 47 67 1.1E-22 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 SMART SM00098 48 501 1.6E-48 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 Gene3D G3DSA:3.40.720.10 43 383 1.5E-92 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 Gene3D G3DSA:3.40.720.10 411 501 7.4E-6 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 Pfam PF00245 Alkaline phosphatase 48 493 7.2E-67 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CLOST_0047 3576c36bbe6a36f8ed1ca09597164320 501 SUPERFAMILY SSF53649 39 500 9.65E-105 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CLOST_2251 43edf21b92b5804172ef1f7bb53e5e17 304 SUPERFAMILY SSF161098 89 286 1.83E-26 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2251 43edf21b92b5804172ef1f7bb53e5e17 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 70 3.6E-14 T 13-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CLOST_2251 43edf21b92b5804172ef1f7bb53e5e17 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 303 1.1E-31 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_2251 43edf21b92b5804172ef1f7bb53e5e17 304 Gene3D G3DSA:1.10.3720.10 84 303 5.9E-24 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1720 270f01ad888edffd95996a19523c0974 363 SUPERFAMILY SSF160544 253 360 2.62E-41 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CLOST_1720 270f01ad888edffd95996a19523c0974 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 281 296 1.1E-42 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1720 270f01ad888edffd95996a19523c0974 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 237 254 1.1E-42 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1720 270f01ad888edffd95996a19523c0974 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 311 332 1.1E-42 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1720 270f01ad888edffd95996a19523c0974 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 217 235 1.1E-42 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1720 270f01ad888edffd95996a19523c0974 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 18 40 1.1E-42 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1720 270f01ad888edffd95996a19523c0974 363 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 15 362 2.2E-122 T 13-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 CLOST_1720 270f01ad888edffd95996a19523c0974 363 Pfam PF01312 FlhB HrpN YscU SpaS Family 15 356 7.8E-126 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1720 270f01ad888edffd95996a19523c0974 363 Gene3D G3DSA:3.40.1690.10 227 363 1.7E-56 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CLOST_2012 b8138a2bf920f2e06f13a137131c71f8 347 PIRSF PIRSF001123 8 346 2.2E-36 T 13-10-2018 IPR008007 Peptidase M42 CLOST_2012 b8138a2bf920f2e06f13a137131c71f8 347 SUPERFAMILY SSF101821 77 189 1.98E-29 T 13-10-2018 CLOST_2012 b8138a2bf920f2e06f13a137131c71f8 347 Gene3D G3DSA:3.40.630.10 18 344 4.3E-115 T 13-10-2018 CLOST_2012 b8138a2bf920f2e06f13a137131c71f8 347 SUPERFAMILY SSF53187 10 344 6.52E-49 T 13-10-2018 CLOST_2012 b8138a2bf920f2e06f13a137131c71f8 347 Gene3D G3DSA:2.40.30.40 80 174 4.3E-115 T 13-10-2018 IPR023367 Peptidase M42, domain 2 CLOST_2012 b8138a2bf920f2e06f13a137131c71f8 347 Pfam PF05343 M42 glutamyl aminopeptidase 53 339 9.0E-73 T 13-10-2018 IPR008007 Peptidase M42 CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 Gene3D G3DSA:2.30.330.10 243 329 3.1E-9 T 13-10-2018 IPR036429 SpoA-like superfamily CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 SUPERFAMILY SSF101801 252 327 2.75E-15 T 13-10-2018 IPR036429 SpoA-like superfamily CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 SUPERFAMILY SSF103039 45 229 3.4E-22 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 Pfam PF02154 Flagellar motor switch protein FliM 39 229 1.2E-60 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 1.7E-22 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 1.7E-22 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 1.7E-22 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 1.7E-22 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 Gene3D G3DSA:3.40.1550.10 45 231 5.2E-59 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 323 1.0E-97 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 323 1.1E-19 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) CLOST_1727 5fa9dee05785a8f010a315e4229a2d63 332 PIRSF PIRSF002888 1 332 2.0E-105 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CLOST_1308 6f6dffa57ec5ef881323acf60b647183 556 SUPERFAMILY SSF56112 98 321 7.24E-27 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily CLOST_1308 6f6dffa57ec5ef881323acf60b647183 556 Pfam PF03109 ABC1 family 116 232 2.7E-29 T 13-10-2018 IPR004147 UbiB domain CLOST_1588 d572111f4e297f2993632bba9934a09f 309 SUPERFAMILY SSF50341 8 154 1.11E-32 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 CLOST_1588 d572111f4e297f2993632bba9934a09f 309 SUPERFAMILY SSF52172 175 303 7.4E-22 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1588 d572111f4e297f2993632bba9934a09f 309 Gene3D G3DSA:3.40.50.2300 174 309 7.4E-24 T 13-10-2018 CLOST_1588 d572111f4e297f2993632bba9934a09f 309 SMART SM00448 175 298 2.9E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1588 d572111f4e297f2993632bba9934a09f 309 Gene3D G3DSA:2.40.50.180 35 150 1.8E-27 T 13-10-2018 CLOST_1588 d572111f4e297f2993632bba9934a09f 309 SMART SM00260 14 150 5.4E-19 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 CLOST_1588 d572111f4e297f2993632bba9934a09f 309 Gene3D G3DSA:2.30.30.40 20 144 1.8E-27 T 13-10-2018 CLOST_1588 d572111f4e297f2993632bba9934a09f 309 Pfam PF00072 Response regulator receiver domain 179 298 1.1E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1588 d572111f4e297f2993632bba9934a09f 309 Pfam PF01584 CheW-like domain 19 152 2.1E-26 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 CLOST_1588 d572111f4e297f2993632bba9934a09f 309 PIRSF PIRSF002867 1 306 3.7E-90 T 13-10-2018 IPR024181 Chemotaxis response regulator CheV CLOST_0030 bc28c4d79116efb48d37c0205c15c2c6 318 Pfam PF00005 ABC transporter 19 164 1.5E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0030 bc28c4d79116efb48d37c0205c15c2c6 318 SUPERFAMILY SSF52540 3 239 4.78E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0030 bc28c4d79116efb48d37c0205c15c2c6 318 SMART SM00382 28 213 7.3E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0030 bc28c4d79116efb48d37c0205c15c2c6 318 Gene3D G3DSA:3.40.50.300 2 269 2.0E-69 T 13-10-2018 CLOST_0030 bc28c4d79116efb48d37c0205c15c2c6 318 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0167 c04bcc903d6bb418afc2863127ae5553 397 Pfam PF13439 Glycosyltransferase Family 4 15 197 7.6E-15 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CLOST_0167 c04bcc903d6bb418afc2863127ae5553 397 Gene3D G3DSA:3.40.50.2000 206 395 6.4E-43 T 13-10-2018 CLOST_0167 c04bcc903d6bb418afc2863127ae5553 397 Pfam PF00534 Glycosyl transferases group 1 214 368 9.0E-35 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 CLOST_0167 c04bcc903d6bb418afc2863127ae5553 397 SUPERFAMILY SSF53756 3 396 6.42E-79 T 13-10-2018 CLOST_0167 c04bcc903d6bb418afc2863127ae5553 397 Gene3D G3DSA:3.40.50.2000 1 205 1.1E-23 T 13-10-2018 CLOST_1781 4cd0b6783915f054a2ca07ee33816136 238 Pfam PF13483 Beta-lactamase superfamily domain 2 136 7.3E-6 T 13-10-2018 CLOST_1781 4cd0b6783915f054a2ca07ee33816136 238 Gene3D G3DSA:3.60.15.10 1 236 4.1E-38 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1781 4cd0b6783915f054a2ca07ee33816136 238 SUPERFAMILY SSF56281 1 208 7.0E-18 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_0327 e17b432d8d3a6dc489c217774c5c45ae 450 SUPERFAMILY SSF55383 49 133 1.83E-28 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0327 e17b432d8d3a6dc489c217774c5c45ae 450 Pfam PF07833 Copper amine oxidase N-terminal domain 28 63 1.3E-5 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0327 e17b432d8d3a6dc489c217774c5c45ae 450 Pfam PF07833 Copper amine oxidase N-terminal domain 47 138 7.1E-33 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0327 e17b432d8d3a6dc489c217774c5c45ae 450 Gene3D G3DSA:3.30.457.10 51 124 6.4E-26 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0709 c33dfb0cd87d0d27682ba8383c7d4f7b 125 Hamap MF_00674 UPF0251 protein . 2 98 21.475 T 13-10-2018 IPR002852 Uncharacterised protein family UPF0251 CLOST_0709 c33dfb0cd87d0d27682ba8383c7d4f7b 125 Pfam PF02001 Protein of unknown function DUF134 3 95 4.8E-23 T 13-10-2018 IPR002852 Uncharacterised protein family UPF0251 CLOST_0709 c33dfb0cd87d0d27682ba8383c7d4f7b 125 SUPERFAMILY SSF88659 35 79 1.07E-5 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_1002 6c6df52bd1ff0d4fcdd2e0498dfd84e1 309 SUPERFAMILY SSF55729 172 299 1.26E-19 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1002 6c6df52bd1ff0d4fcdd2e0498dfd84e1 309 Gene3D G3DSA:3.40.630.30 136 306 2.9E-18 T 13-10-2018 CLOST_1002 6c6df52bd1ff0d4fcdd2e0498dfd84e1 309 Pfam PF00583 Acetyltransferase (GNAT) family 192 293 8.4E-12 T 13-10-2018 IPR000182 GNAT domain CLOST_1780 bafb5b9decd931942f7a8c84b74af816 144 SUPERFAMILY SSF50249 5 89 1.32E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1780 bafb5b9decd931942f7a8c84b74af816 144 SMART SM00316 6 77 9.5E-27 T 13-10-2018 IPR022967 RNA-binding domain, S1 CLOST_1780 bafb5b9decd931942f7a8c84b74af816 144 Pfam PF00575 S1 RNA binding domain 5 77 1.5E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 CLOST_1780 bafb5b9decd931942f7a8c84b74af816 144 Gene3D G3DSA:2.40.50.140 2 87 2.8E-29 T 13-10-2018 CLOST_2449 07087a9c122298b32fda13301a9bfdf3 429 SUPERFAMILY SSF52218 205 344 3.14E-13 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_2449 07087a9c122298b32fda13301a9bfdf3 429 Pfam PF03358 NADPH-dependent FMN reductase 206 309 9.0E-6 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CLOST_2449 07087a9c122298b32fda13301a9bfdf3 429 Pfam PF03358 NADPH-dependent FMN reductase 25 105 1.2E-6 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CLOST_2449 07087a9c122298b32fda13301a9bfdf3 429 Gene3D G3DSA:3.40.50.360 203 360 2.8E-11 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_2449 07087a9c122298b32fda13301a9bfdf3 429 Gene3D G3DSA:3.40.50.360 5 133 1.4E-14 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_2449 07087a9c122298b32fda13301a9bfdf3 429 SUPERFAMILY SSF52218 28 107 7.48E-11 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0242 6698dde89e82e42c195c331273e082be 114 SMART SM00877 42 114 1.2E-14 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0242 6698dde89e82e42c195c331273e082be 114 SUPERFAMILY SSF143414 42 103 4.71E-13 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0242 6698dde89e82e42c195c331273e082be 114 Pfam PF00936 BMC domain 43 98 3.8E-12 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0242 6698dde89e82e42c195c331273e082be 114 Gene3D G3DSA:3.30.70.1710 1 114 7.3E-49 T 13-10-2018 CLOST_0242 6698dde89e82e42c195c331273e082be 114 PIRSF PIRSF012296 1 114 1.3E-52 T 13-10-2018 IPR009307 Ethanolamine utilisation EutS GO:0031469 CLOST_2213 d8e5707f70803728b788d0ebcc6c4776 165 SUPERFAMILY SSF160369 5 162 3.53E-51 T 13-10-2018 CLOST_2213 d8e5707f70803728b788d0ebcc6c4776 165 Gene3D G3DSA:3.30.70.1730 5 136 5.3E-42 T 13-10-2018 CLOST_2213 d8e5707f70803728b788d0ebcc6c4776 165 Pfam PF00466 Ribosomal protein L10 6 103 1.0E-26 T 13-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CLOST_2213 d8e5707f70803728b788d0ebcc6c4776 165 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 81 157 3.0E-4 T 13-10-2018 CLOST_2213 d8e5707f70803728b788d0ebcc6c4776 165 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 163 27.335 T 13-10-2018 IPR022973 Ribosomal protein L10 CLOST_2501 2545f22ff09e66e9cc7a0facd341c196 371 Pfam PF12725 Protein of unknown function (DUF3810) 49 364 9.9E-96 T 13-10-2018 IPR024294 Protein of unknown function DUF3810 CLOST_1431 24fa2662fc8603802f1ddb00c0f25659 250 Gene3D G3DSA:3.90.550.10 1 240 1.3E-29 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_1431 24fa2662fc8603802f1ddb00c0f25659 250 SUPERFAMILY SSF53448 3 231 4.82E-36 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_1431 24fa2662fc8603802f1ddb00c0f25659 250 Pfam PF00535 Glycosyl transferase family 2 6 169 6.6E-26 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CLOST_1675 103055f90fdc750bc7519636268edcd5 296 Pfam PF00565 Staphylococcal nuclease homologue 117 224 2.2E-27 T 13-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 CLOST_1675 103055f90fdc750bc7519636268edcd5 296 ProSitePatterns PS01123 Thermonuclease family signature 1. 103 127 - T 13-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CLOST_1675 103055f90fdc750bc7519636268edcd5 296 Pfam PF02805 Metal binding domain of Ada 249 296 2.3E-6 T 13-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CLOST_1675 103055f90fdc750bc7519636268edcd5 296 SMART SM00318 92 224 4.0E-38 T 13-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 CLOST_1675 103055f90fdc750bc7519636268edcd5 296 SUPERFAMILY SSF57884 245 296 3.4E-15 T 13-10-2018 IPR035451 Ada-like domain superfamily CLOST_1675 103055f90fdc750bc7519636268edcd5 296 SUPERFAMILY SSF50199 96 225 2.48E-35 T 13-10-2018 CLOST_1675 103055f90fdc750bc7519636268edcd5 296 Gene3D G3DSA:2.40.50.90 84 229 1.0E-49 T 13-10-2018 IPR035437 SNase-like, OB-fold superfamily CLOST_1675 103055f90fdc750bc7519636268edcd5 296 ProSitePatterns PS01284 Thermonuclease family signature 2. 166 176 - T 13-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CLOST_1675 103055f90fdc750bc7519636268edcd5 296 Gene3D G3DSA:3.40.10.10 239 296 1.3E-8 T 13-10-2018 IPR035451 Ada-like domain superfamily CLOST_1445 c8b8ef61fd702e93c7cd329e96bc4766 383 Gene3D G3DSA:3.40.640.10 61 236 1.8E-129 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1445 c8b8ef61fd702e93c7cd329e96bc4766 383 PIRSF PIRSF005572 1 380 6.0E-118 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 CLOST_1445 c8b8ef61fd702e93c7cd329e96bc4766 383 Gene3D G3DSA:3.90.1150.10 3 370 1.8E-129 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1445 c8b8ef61fd702e93c7cd329e96bc4766 383 SUPERFAMILY SSF53383 3 373 2.64E-86 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1445 c8b8ef61fd702e93c7cd329e96bc4766 383 Pfam PF00266 Aminotransferase class-V 3 363 7.2E-74 T 13-10-2018 IPR000192 Aminotransferase class V domain CLOST_1445 c8b8ef61fd702e93c7cd329e96bc4766 383 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CLOST_1445 c8b8ef61fd702e93c7cd329e96bc4766 383 Gene3D G3DSA:1.10.260.50 14 280 1.8E-129 T 13-10-2018 CLOST_0617 dea33149a1953da99330beed5661f826 178 Gene3D G3DSA:1.10.15.40 114 172 6.9E-17 T 13-10-2018 CLOST_0617 dea33149a1953da99330beed5661f826 178 Pfam PF04060 Putative Fe-S cluster 123 154 1.2E-11 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 CLOST_0266 f60f5969a4e96967680663930044e5de 73 SUPERFAMILY SSF50037 5 73 1.8E-20 T 13-10-2018 IPR008988 Transcriptional repressor, C-terminal CLOST_0266 f60f5969a4e96967680663930044e5de 73 Gene3D G3DSA:2.30.30.90 1 73 5.2E-25 T 13-10-2018 IPR038157 Ferrous iron transporter, core domain CLOST_0266 f60f5969a4e96967680663930044e5de 73 SMART SM00899 2 73 3.7E-22 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOST_0266 f60f5969a4e96967680663930044e5de 73 Pfam PF04023 FeoA domain 3 73 8.1E-19 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOST_1164 ab01f61e157de26e2e04d77d754103bb 215 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 109 203 4.5E-36 T 13-10-2018 IPR022026 Methylene-tetrahydrofolate reductase C-terminal CLOST_1578 0617f28f2823042a99a9eebd6c4e0444 76 Pfam PF13083 KH domain 3 74 1.3E-24 T 13-10-2018 CLOST_1578 0617f28f2823042a99a9eebd6c4e0444 76 SUPERFAMILY SSF54814 6 61 2.35E-7 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CLOST_1578 0617f28f2823042a99a9eebd6c4e0444 76 Gene3D G3DSA:3.30.300.20 5 72 3.5E-5 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta CLOST_1578 0617f28f2823042a99a9eebd6c4e0444 76 Hamap MF_00088 UPF0109 protein . 1 75 23.258 T 13-10-2018 IPR020627 Uncharacterised protein family UPF0109 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.5E-5 T 13-10-2018 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.5E-5 T 13-10-2018 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 Gene3D G3DSA:1.10.150.570 568 620 2.7E-23 T 13-10-2018 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 Gene3D G3DSA:1.10.10.1800 460 549 2.2E-19 T 13-10-2018 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 Pfam PF01134 Glucose inhibited division protein A 9 399 4.6E-156 T 13-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 Pfam PF13932 GidA associated domain 402 615 3.2E-78 T 13-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 622 2.6E-266 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 SUPERFAMILY SSF51905 8 262 8.75E-40 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 SMART SM01228 545 616 5.6E-43 T 13-10-2018 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 Gene3D G3DSA:3.50.50.60 305 459 2.7E-56 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 Gene3D G3DSA:3.50.50.60 1 237 1.7E-78 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 162 1.6E-6 T 13-10-2018 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.6E-6 T 13-10-2018 CLOST_2581 56389cf36c77f52a00746367fbed2f5f 631 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 40.873 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CLOST_1702 432cbb2bfbebc7c2a1d6a0ef614d348a 185 Pfam PF01765 Ribosome recycling factor 20 183 1.5E-67 T 13-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CLOST_1702 432cbb2bfbebc7c2a1d6a0ef614d348a 185 SUPERFAMILY SSF55194 5 184 1.23E-72 T 13-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 CLOST_1702 432cbb2bfbebc7c2a1d6a0ef614d348a 185 Gene3D G3DSA:3.30.1360.40 31 105 5.3E-70 T 13-10-2018 CLOST_1702 432cbb2bfbebc7c2a1d6a0ef614d348a 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 5.7E-72 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CLOST_1702 432cbb2bfbebc7c2a1d6a0ef614d348a 185 Gene3D G3DSA:1.10.132.20 12 182 5.3E-70 T 13-10-2018 CLOST_1702 432cbb2bfbebc7c2a1d6a0ef614d348a 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.973 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CLOST_1791 8e592285435f12e9dce0f35fb963cd10 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 36.659 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CLOST_1791 8e592285435f12e9dce0f35fb963cd10 312 SUPERFAMILY SSF53335 101 309 2.07E-50 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1791 8e592285435f12e9dce0f35fb963cd10 312 PIRSF PIRSF000401 1 312 2.9E-111 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CLOST_1791 8e592285435f12e9dce0f35fb963cd10 312 Gene3D G3DSA:3.40.50.150 117 311 3.2E-64 T 13-10-2018 CLOST_1791 8e592285435f12e9dce0f35fb963cd10 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 310 1.1E-101 T 13-10-2018 CLOST_1791 8e592285435f12e9dce0f35fb963cd10 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 304 2.5E-80 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CLOST_2531 6a1ff79f8158201bc1d0284dc2429217 333 Pfam PF06616 BsuBI/PstI restriction endonuclease C-terminus 131 328 3.7E-23 T 13-10-2018 IPR009528 Restriction endonuclease, type II, BsuBI/PstI, C-terminal GO:0000287|GO:0003677|GO:0009036|GO:0009307 CLOST_2531 6a1ff79f8158201bc1d0284dc2429217 333 Gene3D G3DSA:3.40.1350.80 181 333 5.3E-23 T 13-10-2018 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 SUPERFAMILY SSF55831 3 269 3.01E-63 T 13-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 Pfam PF00303 Thymidylate synthase 8 276 5.8E-62 T 13-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 Gene3D G3DSA:3.30.572.10 2 277 5.4E-69 T 13-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 PRINTS PR00108 Thymidylate synthase family signature 56 77 8.0E-15 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 PRINTS PR00108 Thymidylate synthase family signature 168 194 8.0E-15 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 PRINTS PR00108 Thymidylate synthase family signature 206 223 8.0E-15 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 PRINTS PR00108 Thymidylate synthase family signature 123 142 8.0E-15 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 Hamap MF_00008 Thymidylate synthase [thyA]. 5 277 32.121 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_2475 a0b795ea806a420f6c90164333fd2d94 277 ProSitePatterns PS00091 Thymidylate synthase active site. 134 163 - T 13-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CLOST_1985 1d4d02bb831b78aac470bea354e7e82a 198 PRINTS PR01837 MgtC/SapB protein signature 28 50 2.0E-24 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOST_1985 1d4d02bb831b78aac470bea354e7e82a 198 PRINTS PR01837 MgtC/SapB protein signature 3 21 2.0E-24 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOST_1985 1d4d02bb831b78aac470bea354e7e82a 198 PRINTS PR01837 MgtC/SapB protein signature 55 79 2.0E-24 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOST_1985 1d4d02bb831b78aac470bea354e7e82a 198 Pfam PF02308 MgtC family 6 99 1.4E-21 T 13-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CLOST_1039 51e4878c8927d893064d65c138bd8e7e 435 Gene3D G3DSA:3.30.950.30 3 119 1.3E-26 T 13-10-2018 IPR038461 Schlafen, AAA domain superfamily CLOST_1039 51e4878c8927d893064d65c138bd8e7e 435 SUPERFAMILY SSF46785 375 429 3.67E-6 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1039 51e4878c8927d893064d65c138bd8e7e 435 Pfam PF04326 Putative DNA-binding domain 7 113 1.0E-19 T 13-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 CLOST_1039 51e4878c8927d893064d65c138bd8e7e 435 Gene3D G3DSA:3.30.565.60 193 358 1.6E-39 T 13-10-2018 IPR038475 RecG, C-terminal domain superfamily CLOST_1039 51e4878c8927d893064d65c138bd8e7e 435 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 275 357 6.7E-19 T 13-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain CLOST_1039 51e4878c8927d893064d65c138bd8e7e 435 Gene3D G3DSA:1.10.10.10 374 432 3.9E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0810 767701c95c9101d6bd9c751e9dcdbbda 665 SUPERFAMILY SSF52540 169 424 1.01E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0810 767701c95c9101d6bd9c751e9dcdbbda 665 Gene3D G3DSA:3.40.50.300 165 367 4.5E-18 T 13-10-2018 CLOST_0853 b9bc9f6ff05dd56b413c514702349171 248 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 13-10-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 CLOST_0853 b9bc9f6ff05dd56b413c514702349171 248 Gene3D G3DSA:3.40.50.1360 1 248 4.5E-93 T 13-10-2018 CLOST_0853 b9bc9f6ff05dd56b413c514702349171 248 SUPERFAMILY SSF100950 1 244 2.72E-90 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_0853 b9bc9f6ff05dd56b413c514702349171 248 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 12 227 2.7E-21 T 13-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CLOST_0853 b9bc9f6ff05dd56b413c514702349171 248 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 242 2.9E-86 T 13-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 CLOST_0853 b9bc9f6ff05dd56b413c514702349171 248 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 40.434 T 13-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 Pfam PF00557 Metallopeptidase family M24 312 530 4.1E-40 T 13-10-2018 IPR000994 Peptidase M24 CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 SUPERFAMILY SSF53092 4 135 3.66E-14 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 Gene3D G3DSA:3.90.230.10 303 599 3.1E-87 T 13-10-2018 CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 SUPERFAMILY SSF55920 306 565 1.57E-53 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 Gene3D G3DSA:3.40.350.10 2 149 2.3E-52 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 Pfam PF16189 Creatinase/Prolidase N-terminal domain 151 309 4.5E-48 T 13-10-2018 CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 Pfam PF16188 C-terminal region of peptidase_M24 539 599 8.4E-21 T 13-10-2018 IPR032416 Peptidase M24, C-terminal domain CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 Gene3D G3DSA:3.40.350.10 150 298 4.7E-43 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CLOST_0803 b02e68da3a62c1599a48b8f425571a35 603 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 136 1.3E-18 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 CLOST_1399 02ce5ca5486c2283f35cb9214b5ea4a1 207 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 5 194 5.4E-81 T 13-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 CLOST_1399 02ce5ca5486c2283f35cb9214b5ea4a1 207 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 185 2.7E-69 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 CLOST_1399 02ce5ca5486c2283f35cb9214b5ea4a1 207 Hamap MF_00478 Ion-translocating oxidoreductase complex subunit E [rsxE]. 3 196 26.875 T 13-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 CLOST_1399 02ce5ca5486c2283f35cb9214b5ea4a1 207 PIRSF PIRSF006102 1 205 1.0E-75 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 CLOST_0924 2671eaa31ffe1ef814dd901da6579332 412 Gene3D G3DSA:1.20.1250.20 1 407 3.5E-58 T 13-10-2018 CLOST_0924 2671eaa31ffe1ef814dd901da6579332 412 Pfam PF07690 Major Facilitator Superfamily 31 307 2.1E-30 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOST_0924 2671eaa31ffe1ef814dd901da6579332 412 SUPERFAMILY SSF103473 5 401 1.57E-59 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_1236 7677562a80b699bd7fcd802dce763696 105 SUPERFAMILY SSF54106 48 99 4.97E-7 T 13-10-2018 CLOST_1236 7677562a80b699bd7fcd802dce763696 105 Gene3D G3DSA:3.10.350.10 36 104 1.5E-11 T 13-10-2018 IPR036779 LysM domain superfamily CLOST_1236 7677562a80b699bd7fcd802dce763696 105 Pfam PF01476 LysM domain 50 99 1.2E-8 T 13-10-2018 IPR018392 LysM domain CLOST_1236 7677562a80b699bd7fcd802dce763696 105 SMART SM00257 49 99 2.2E-7 T 13-10-2018 IPR018392 LysM domain CLOST_2106 d46f9e0e2b5591010b6f8427688b3956 251 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 59 232 3.8E-65 T 13-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 CLOST_2106 d46f9e0e2b5591010b6f8427688b3956 251 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 54 237 2.2E-51 T 13-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 CLOST_2106 d46f9e0e2b5591010b6f8427688b3956 251 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 2 248 62.922 T 13-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 CLOST_1222 070edc939c6ec308f7cd9e91f5ff9181 438 SUPERFAMILY SSF53383 6 431 6.05E-57 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1222 070edc939c6ec308f7cd9e91f5ff9181 438 Pfam PF00155 Aminotransferase class I and II 68 413 1.4E-28 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_1222 070edc939c6ec308f7cd9e91f5ff9181 438 Gene3D G3DSA:3.40.640.10 71 305 7.1E-53 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1222 070edc939c6ec308f7cd9e91f5ff9181 438 Gene3D G3DSA:3.90.1150.10 35 421 7.1E-53 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 SUPERFAMILY SSF55200 83 170 1.16E-30 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 8 170 5.2E-65 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 Gene3D G3DSA:3.10.20.80 2 79 4.2E-33 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 2 171 29.494 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 SUPERFAMILY SSF54364 7 79 1.24E-28 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 ProSitePatterns PS00938 Initiation factor 3 signature. 59 72 - T 13-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 169 7.2E-34 T 13-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 8 76 5.2E-31 T 13-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CLOST_1129 ec7adaab8960f4b87f116bef4f28d77e 171 Gene3D G3DSA:3.30.110.10 80 171 6.0E-35 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 CLOST_0100 72d1d7d71b4db2a174c4a13c119c4ce7 191 Gene3D G3DSA:3.40.50.880 1 191 1.5E-65 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0100 72d1d7d71b4db2a174c4a13c119c4ce7 191 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 187 33.532 T 13-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0100 72d1d7d71b4db2a174c4a13c119c4ce7 191 PIRSF PIRSF005639 1 191 5.2E-70 T 13-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0100 72d1d7d71b4db2a174c4a13c119c4ce7 191 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 13-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0100 72d1d7d71b4db2a174c4a13c119c4ce7 191 Pfam PF01174 SNO glutamine amidotransferase family 6 189 6.1E-59 T 13-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0100 72d1d7d71b4db2a174c4a13c119c4ce7 191 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 4 186 6.1E-70 T 13-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CLOST_0100 72d1d7d71b4db2a174c4a13c119c4ce7 191 SUPERFAMILY SSF52317 3 186 2.07E-50 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 Gene3D G3DSA:3.30.2130.10 284 441 3.3E-61 T 13-10-2018 CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 PIRSF PIRSF000726 2 441 1.6E-81 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 SUPERFAMILY SSF55021 287 359 2.95E-13 T 13-10-2018 CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 SUPERFAMILY SSF53633 4 279 6.94E-59 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 ProSitePatterns PS00324 Aspartokinase signature. 6 14 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 SUPERFAMILY SSF55021 365 439 2.96E-21 T 13-10-2018 CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 Pfam PF00696 Amino acid kinase family 4 265 5.1E-31 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 438 3.8E-81 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 CLOST_1413 63130f3c2b934fc73ca7cdd992a86544 442 Gene3D G3DSA:3.40.1160.10 2 278 6.2E-82 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_0381 512cf36f45c635c17235d969821593f0 247 Pfam PF01048 Phosphorylase superfamily 14 196 1.9E-32 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CLOST_0381 512cf36f45c635c17235d969821593f0 247 SUPERFAMILY SSF53167 3 213 1.03E-63 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 CLOST_0381 512cf36f45c635c17235d969821593f0 247 Gene3D G3DSA:3.40.50.1580 2 240 2.1E-71 T 13-10-2018 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 6.3E-22 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 2.8E-187 T 13-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 SMART SM00963 2 87 1.1E-32 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 SMART SM00962 101 296 1.1E-113 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 Gene3D G3DSA:1.20.120.140 5 306 6.4E-128 T 13-10-2018 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 SMART SM00382 100 247 1.6E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1580 cc5e116319419661c99be9d610133a3e 448 Gene3D G3DSA:3.40.50.300 92 285 6.4E-128 T 13-10-2018 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 436 34.734 T 13-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 SUPERFAMILY SSF47446 327 429 4.09E-39 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 Pfam PF02978 Signal peptide binding domain 328 426 2.0E-36 T 13-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 SUPERFAMILY SSF52540 43 354 1.09E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1580 cc5e116319419661c99be9d610133a3e 448 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 5.5E-77 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1580 cc5e116319419661c99be9d610133a3e 448 Gene3D G3DSA:1.10.260.30 327 445 1.3E-45 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CLOST_2413 ed04c57367f119fde80da0ea4807bcee 136 Pfam PF05025 RbsD / FucU transport protein family 1 131 1.5E-48 T 13-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CLOST_2413 ed04c57367f119fde80da0ea4807bcee 136 SUPERFAMILY SSF102546 1 133 3.66E-44 T 13-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CLOST_2413 ed04c57367f119fde80da0ea4807bcee 136 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 133 31.456 T 13-10-2018 IPR023064 D-ribose pyranase GO:0016872 CLOST_2413 ed04c57367f119fde80da0ea4807bcee 136 Gene3D G3DSA:3.40.1650.10 8 130 4.8E-41 T 13-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CLOST_0987 b8cfba087f0fd6432819b82672c2f33d 214 SUPERFAMILY SSF63965 9 212 2.22E-64 T 13-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 CLOST_0987 b8cfba087f0fd6432819b82672c2f33d 214 Gene3D G3DSA:3.40.50.10230 1 214 8.6E-75 T 13-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 CLOST_0987 b8cfba087f0fd6432819b82672c2f33d 214 Pfam PF02570 Precorrin-8X methylmutase 9 208 9.5E-70 T 13-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Pfam PF01588 Putative tRNA binding domain 45 132 1.9E-18 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 SUPERFAMILY SSF56037 207 396 2.62E-64 T 13-10-2018 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Gene3D G3DSA:3.30.70.380 694 787 3.2E-30 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Gene3D G3DSA:3.30.56.10 406 478 8.4E-24 T 13-10-2018 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 786 7.6E-250 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 SMART SM00874 407 475 3.3E-24 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 SMART SM00896 693 786 4.0E-41 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 SUPERFAMILY SSF55681 471 679 2.88E-40 T 13-10-2018 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 SMART SM00873 217 389 2.0E-77 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Gene3D G3DSA:2.40.50.140 39 159 3.3E-65 T 13-10-2018 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Gene3D G3DSA:3.30.930.10 492 679 1.2E-51 T 13-10-2018 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Gene3D G3DSA:3.50.40.10 202 400 1.8E-77 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Pfam PF03147 Ferredoxin-fold anticodon binding domain 693 786 2.8E-28 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 SUPERFAMILY SSF54991 689 786 1.7E-30 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 SUPERFAMILY SSF50249 39 196 2.09E-41 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 SUPERFAMILY SSF46955 407 478 1.37E-18 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 780 41.393 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Pfam PF03483 B3/4 domain 218 387 7.2E-61 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Pfam PF03484 tRNA synthetase B5 domain 411 475 1.2E-19 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CLOST_1143 b1f36b09094698b4a03eb5ac30c2c77d 788 Gene3D G3DSA:3.30.56.10 5 186 3.3E-65 T 13-10-2018 CLOST_1358 1a57127f68f15f4b6be00974a1cfa65d 472 SUPERFAMILY SSF53383 78 471 1.77E-52 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1358 1a57127f68f15f4b6be00974a1cfa65d 472 Pfam PF03841 L-seryl-tRNA selenium transferase 89 455 4.7E-157 T 13-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CLOST_1358 1a57127f68f15f4b6be00974a1cfa65d 472 Gene3D G3DSA:3.40.640.10 100 364 1.5E-165 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1358 1a57127f68f15f4b6be00974a1cfa65d 472 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 472 190.11 T 13-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CLOST_1358 1a57127f68f15f4b6be00974a1cfa65d 472 Gene3D G3DSA:3.90.1150.110 14 460 1.5E-165 T 13-10-2018 CLOST_1358 1a57127f68f15f4b6be00974a1cfa65d 472 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 11 469 1.7E-179 T 13-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CLOST_2240 2128db81c735ed2e817955d4750d3f75 119 Gene3D G3DSA:1.10.1520.10 1 118 6.6E-36 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 CLOST_2240 2128db81c735ed2e817955d4750d3f75 119 SUPERFAMILY SSF69065 1 111 1.57E-30 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 CLOST_2240 2128db81c735ed2e817955d4750d3f75 119 PIRSF PIRSF005520 1 118 3.0E-41 T 13-10-2018 IPR008226 Mini-ribonuclease 3 family CLOST_2240 2128db81c735ed2e817955d4750d3f75 119 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 1 113 22.235 T 13-10-2018 IPR008226 Mini-ribonuclease 3 family CLOST_2240 2128db81c735ed2e817955d4750d3f75 119 Pfam PF00636 Ribonuclease III domain 1 96 1.8E-11 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 CLOST_0377 b6dc5652f241a1b53f04530a33f911b9 353 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 331 9.2E-38 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_1348 29f1a8ae5b88f77784f1341f8e55a180 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 4.5E-10 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_1348 29f1a8ae5b88f77784f1341f8e55a180 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 4.5E-10 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_1348 29f1a8ae5b88f77784f1341f8e55a180 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 265 274 4.5E-10 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_1348 29f1a8ae5b88f77784f1341f8e55a180 322 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 4.5E-10 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_1348 29f1a8ae5b88f77784f1341f8e55a180 322 SUPERFAMILY SSF53067 4 311 2.59E-16 T 13-10-2018 CLOST_1348 29f1a8ae5b88f77784f1341f8e55a180 322 Gene3D G3DSA:3.30.420.40 7 311 1.7E-49 T 13-10-2018 CLOST_1348 29f1a8ae5b88f77784f1341f8e55a180 322 Pfam PF00814 Glycoprotease family 68 304 4.3E-14 T 13-10-2018 IPR000905 Gcp-like domain CLOST_1348 29f1a8ae5b88f77784f1341f8e55a180 322 Gene3D G3DSA:3.30.420.40 125 295 1.7E-49 T 13-10-2018 CLOST_0110 15a5229b0af0191139a2067244d2c971 200 SMART SM00493 81 166 9.9E-15 T 13-10-2018 IPR006171 TOPRIM domain CLOST_0110 15a5229b0af0191139a2067244d2c971 200 TIGRFAM TIGR00615 recR: recombination protein RecR 4 197 2.0E-83 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CLOST_0110 15a5229b0af0191139a2067244d2c971 200 Pfam PF13662 Toprim domain 82 172 5.8E-25 T 13-10-2018 IPR006171 TOPRIM domain CLOST_0110 15a5229b0af0191139a2067244d2c971 200 Gene3D G3DSA:3.40.1360.10 78 199 6.4E-48 T 13-10-2018 CLOST_0110 15a5229b0af0191139a2067244d2c971 200 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 104.652 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CLOST_0110 15a5229b0af0191139a2067244d2c971 200 Pfam PF02132 RecR protein 40 78 7.8E-15 T 13-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CLOST_0110 15a5229b0af0191139a2067244d2c971 200 Gene3D G3DSA:1.10.8.420 1 54 2.8E-22 T 13-10-2018 CLOST_0110 15a5229b0af0191139a2067244d2c971 200 SUPERFAMILY SSF111304 4 199 8.89E-76 T 13-10-2018 IPR023627 Recombination protein RecR CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 Gene3D G3DSA:1.10.10.410 406 467 1.3E-18 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 SUPERFAMILY SSF55931 1 287 2.03E-121 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 466 1.2E-163 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 1 467 35.013 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 Gene3D G3DSA:1.10.150.380 291 405 2.5E-25 T 13-10-2018 CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 Pfam PF02637 GatB domain 321 465 6.9E-39 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 137 151 - T 13-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 SUPERFAMILY SSF89095 291 393 2.22E-22 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 Pfam PF02934 GatB/GatE catalytic domain 1 281 2.3E-114 T 13-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CLOST_0020 7a2e1dd1b1de65182052142b2acab660 468 SMART SM00845 321 466 2.7E-49 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CLOST_0393 956f0e0b9b85767fb4b72ce530abf0e4 357 SUPERFAMILY SSF55920 130 357 2.09E-73 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like CLOST_0393 956f0e0b9b85767fb4b72ce530abf0e4 357 Gene3D G3DSA:3.40.350.10 2 131 7.9E-22 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CLOST_0393 956f0e0b9b85767fb4b72ce530abf0e4 357 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 131 1.1E-15 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 CLOST_0393 956f0e0b9b85767fb4b72ce530abf0e4 357 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 287 299 - T 13-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CLOST_0393 956f0e0b9b85767fb4b72ce530abf0e4 357 SUPERFAMILY SSF53092 4 130 1.92E-15 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CLOST_0393 956f0e0b9b85767fb4b72ce530abf0e4 357 Pfam PF00557 Metallopeptidase family M24 139 341 1.7E-63 T 13-10-2018 IPR000994 Peptidase M24 CLOST_0393 956f0e0b9b85767fb4b72ce530abf0e4 357 Gene3D G3DSA:3.90.230.10 132 357 2.6E-78 T 13-10-2018 CLOST_0897 08de29a84842e70ddd1abd187b52519a 328 SUPERFAMILY SSF52151 4 308 1.75E-70 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase CLOST_0897 08de29a84842e70ddd1abd187b52519a 328 Gene3D G3DSA:3.40.366.10 5 285 8.4E-88 T 13-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 CLOST_0897 08de29a84842e70ddd1abd187b52519a 328 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 296 4.1E-22 T 13-10-2018 IPR020801 Polyketide synthase, acyl transferase domain CLOST_0897 08de29a84842e70ddd1abd187b52519a 328 SUPERFAMILY SSF55048 129 196 7.19E-17 T 13-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding CLOST_0897 08de29a84842e70ddd1abd187b52519a 328 Pfam PF00698 Acyl transferase domain 6 289 7.2E-31 T 13-10-2018 IPR014043 Acyl transferase CLOST_0897 08de29a84842e70ddd1abd187b52519a 328 PIRSF PIRSF000446 1 310 4.4E-100 T 13-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CLOST_0897 08de29a84842e70ddd1abd187b52519a 328 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 290 1.7E-98 T 13-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CLOST_0897 08de29a84842e70ddd1abd187b52519a 328 Gene3D G3DSA:3.30.70.250 127 196 8.4E-88 T 13-10-2018 CLOST_1656 83af1cb3601e036ab1665cef1f13b7bf 332 SUPERFAMILY SSF142338 2 316 6.28E-95 T 13-10-2018 CLOST_1656 83af1cb3601e036ab1665cef1f13b7bf 332 Hamap MF_00973 Gluconeogenesis factor. 1 321 33.417 T 13-10-2018 IPR010119 Gluconeogenesis factor CLOST_1656 83af1cb3601e036ab1665cef1f13b7bf 332 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 5 319 3.9E-111 T 13-10-2018 IPR010119 Gluconeogenesis factor CLOST_1656 83af1cb3601e036ab1665cef1f13b7bf 332 Gene3D G3DSA:3.40.50.12300 1 330 1.3E-118 T 13-10-2018 IPR038136 Gluconeogenesis factor superfamily CLOST_1656 83af1cb3601e036ab1665cef1f13b7bf 332 Pfam PF01933 Uncharacterised protein family UPF0052 5 296 5.1E-99 T 13-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 Gene3D G3DSA:3.40.50.620 12 179 4.2E-146 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 SUPERFAMILY SSF52402 9 172 1.04E-43 T 13-10-2018 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 Pfam PF00764 Arginosuccinate synthase 13 399 7.1E-154 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 Hamap MF_00005 Argininosuccinate synthase [argG]. 9 405 51.43 T 13-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 TIGRFAM TIGR00032 argG: argininosuccinate synthase 11 404 1.4E-147 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 SUPERFAMILY SSF69864 178 407 3.27E-84 T 13-10-2018 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 Gene3D G3DSA:1.20.5.470 381 407 5.7E-8 T 13-10-2018 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 Gene3D G3DSA:3.90.1260.10 70 359 4.2E-146 T 13-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 15 23 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_0141 6257bfadc0592323a9b87a49d2c34dae 421 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 123 134 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_1100 6b33a104ee80dadd389149fa421cd729 468 Pfam PF07501 G5 domain 370 432 5.9E-12 T 13-10-2018 IPR011098 G5 domain CLOST_1100 6b33a104ee80dadd389149fa421cd729 468 Gene3D G3DSA:2.20.230.10 361 432 4.3E-11 T 13-10-2018 CLOST_1100 6b33a104ee80dadd389149fa421cd729 468 Pfam PF12229 Putative peptidoglycan binding domain 73 187 3.0E-14 T 13-10-2018 IPR022029 Putative peptidoglycan binding domain CLOST_1100 6b33a104ee80dadd389149fa421cd729 468 Pfam PF04294 VanW like protein 227 355 3.0E-51 T 13-10-2018 IPR007391 Vancomycin resistance VanW CLOST_1100 6b33a104ee80dadd389149fa421cd729 468 SMART SM01208 362 434 1.4E-12 T 13-10-2018 IPR011098 G5 domain CLOST_0837 6c0c3a8f3c57c6bde582209f6ce9d02b 292 SUPERFAMILY SSF53927 27 251 4.21E-50 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CLOST_0837 6c0c3a8f3c57c6bde582209f6ce9d02b 292 Gene3D G3DSA:3.40.140.10 116 262 2.3E-39 T 13-10-2018 CLOST_0837 6c0c3a8f3c57c6bde582209f6ce9d02b 292 Pfam PF02634 FdhD/NarQ family 127 252 1.6E-39 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CLOST_0837 6c0c3a8f3c57c6bde582209f6ce9d02b 292 Gene3D G3DSA:3.10.20.10 48 115 5.3E-6 T 13-10-2018 CLOST_0837 6c0c3a8f3c57c6bde582209f6ce9d02b 292 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 49 253 1.8E-44 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CLOST_1869 704c612771cbe512d29340c8f5fbb259 177 Pfam PF00156 Phosphoribosyl transferase domain 9 150 1.5E-22 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOST_1869 704c612771cbe512d29340c8f5fbb259 177 Gene3D G3DSA:3.40.50.2020 1 177 2.6E-56 T 13-10-2018 CLOST_1869 704c612771cbe512d29340c8f5fbb259 177 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 37.999 T 13-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CLOST_1869 704c612771cbe512d29340c8f5fbb259 177 SUPERFAMILY SSF53271 7 173 2.36E-40 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_1467 b54aca3b43cef0965c37464dedbe6861 193 Pfam PF01553 Acyltransferase 22 147 2.8E-23 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 CLOST_1467 b54aca3b43cef0965c37464dedbe6861 193 SUPERFAMILY SSF69593 5 192 9.42E-38 T 13-10-2018 CLOST_1467 b54aca3b43cef0965c37464dedbe6861 193 SMART SM00563 37 150 8.9E-28 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 CLOST_1635 afddb9ab454b5b76266192def7ea311a 170 SUPERFAMILY SSF53597 3 161 1.05E-24 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 CLOST_1635 afddb9ab454b5b76266192def7ea311a 170 Gene3D G3DSA:3.40.430.10 2 170 9.0E-31 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 CLOST_1635 afddb9ab454b5b76266192def7ea311a 170 Pfam PF01872 RibD C-terminal domain 102 161 6.4E-11 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CLOST_2377 9d621a3e27d2d24bc04becd7967c0197 370 TIGRFAM TIGR00033 aroC: chorismate synthase 9 359 9.1E-120 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CLOST_2377 9d621a3e27d2d24bc04becd7967c0197 370 Hamap MF_00300 Chorismate synthase [aroC]. 9 364 34.493 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CLOST_2377 9d621a3e27d2d24bc04becd7967c0197 370 SUPERFAMILY SSF103263 3 358 9.29E-117 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CLOST_2377 9d621a3e27d2d24bc04becd7967c0197 370 PIRSF PIRSF001456 2 368 1.1E-130 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CLOST_2377 9d621a3e27d2d24bc04becd7967c0197 370 Pfam PF01264 Chorismate synthase 9 357 2.3E-127 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CLOST_2377 9d621a3e27d2d24bc04becd7967c0197 370 Gene3D G3DSA:3.60.150.10 1 368 7.2E-140 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CLOST_2377 9d621a3e27d2d24bc04becd7967c0197 370 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CLOST_2377 9d621a3e27d2d24bc04becd7967c0197 370 ProSitePatterns PS00789 Chorismate synthase signature 3. 331 347 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CLOST_2179 d049e7adefe9c417bed037e3d40dd89b 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 146 1.6E-39 T 13-10-2018 IPR021131 Ribosomal protein L18e/L15P CLOST_2179 d049e7adefe9c417bed037e3d40dd89b 148 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 145 2.4E-52 T 13-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2179 d049e7adefe9c417bed037e3d40dd89b 148 Gene3D G3DSA:3.100.10.10 70 148 7.3E-25 T 13-10-2018 CLOST_2179 d049e7adefe9c417bed037e3d40dd89b 148 SUPERFAMILY SSF52080 4 147 1.31E-47 T 13-10-2018 IPR036227 Ribosomal L18e/L15P superfamily CLOST_2179 d049e7adefe9c417bed037e3d40dd89b 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 148 22.407 T 13-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CLOST_2179 d049e7adefe9c417bed037e3d40dd89b 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 13-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 SUPERFAMILY SSF88659 171 246 1.63E-21 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 Pfam PF04542 Sigma-70 region 2 28 99 4.0E-15 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 SUPERFAMILY SSF88659 100 164 1.44E-12 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 54 67 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 107 6.3E-14 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 169 244 3.3E-19 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 27 245 4.1E-74 T 13-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 PIRSF PIRSF000770 11 247 7.0E-46 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 SUPERFAMILY SSF88946 13 99 3.3E-26 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 215 241 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 Gene3D G3DSA:1.20.140.160 98 247 8.2E-43 T 13-10-2018 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 PRINTS PR00046 Major sigma-70 factor signature 54 67 2.4E-12 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 PRINTS PR00046 Major sigma-70 factor signature 215 230 2.4E-12 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 PRINTS PR00046 Major sigma-70 factor signature 230 241 2.4E-12 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 PRINTS PR00046 Major sigma-70 factor signature 198 210 2.4E-12 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 Gene3D G3DSA:1.10.1740.10 12 97 8.7E-30 T 13-10-2018 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 Pfam PF04539 Sigma-70 region 3 111 163 1.2E-8 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 CLOST_1709 65e40c555a77507c8a580eff1ae8a27a 247 Pfam PF04545 Sigma-70, region 4 195 243 2.6E-20 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 CLOST_2034 f9a2e37c564d53edf70e6998a2df5fa7 138 Pfam PF01814 Hemerythrin HHE cation binding domain 11 126 4.2E-12 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CLOST_2034 f9a2e37c564d53edf70e6998a2df5fa7 138 ProSitePatterns PS00550 Hemerythrin family signature. 60 83 - T 13-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 CLOST_2034 f9a2e37c564d53edf70e6998a2df5fa7 138 Gene3D G3DSA:1.20.120.50 1 137 2.1E-33 T 13-10-2018 IPR035938 Hemerythrin-like superfamily CLOST_2034 f9a2e37c564d53edf70e6998a2df5fa7 138 SUPERFAMILY SSF47188 1 131 5.76E-29 T 13-10-2018 IPR035938 Hemerythrin-like superfamily CLOST_2034 f9a2e37c564d53edf70e6998a2df5fa7 138 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 4 130 2.9E-33 T 13-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CLOST_2017 e8dcfe51e5c04d573aa7275c39dd5cfe 332 Gene3D G3DSA:3.40.50.150 134 332 6.7E-44 T 13-10-2018 CLOST_2017 e8dcfe51e5c04d573aa7275c39dd5cfe 332 Pfam PF06803 Protein of unknown function (DUF1232) 87 119 5.4E-7 T 13-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 CLOST_2017 e8dcfe51e5c04d573aa7275c39dd5cfe 332 Pfam PF13489 Methyltransferase domain 158 272 6.3E-11 T 13-10-2018 CLOST_2017 e8dcfe51e5c04d573aa7275c39dd5cfe 332 SUPERFAMILY SSF53335 145 310 3.19E-21 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1340 d23a527630cde007d0c11bd851ff1134 559 PIRSF PIRSF003128 1 559 2.6E-158 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CLOST_1340 d23a527630cde007d0c11bd851ff1134 559 SUPERFAMILY SSF52540 1 525 8.32E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1340 d23a527630cde007d0c11bd851ff1134 559 Gene3D G3DSA:3.40.50.300 283 558 1.1E-49 T 13-10-2018 CLOST_1340 d23a527630cde007d0c11bd851ff1134 559 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 515 8.6E-22 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal CLOST_1340 d23a527630cde007d0c11bd851ff1134 559 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 557 2.6E-143 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CLOST_1340 d23a527630cde007d0c11bd851ff1134 559 Gene3D G3DSA:3.40.50.300 1 215 2.1E-37 T 13-10-2018 CLOST_0365 77cc938d00aabe04e7ea43a3143f6fcc 348 Gene3D G3DSA:3.90.550.10 120 348 7.4E-57 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0365 77cc938d00aabe04e7ea43a3143f6fcc 348 Pfam PF00483 Nucleotidyl transferase 122 345 1.0E-28 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CLOST_0365 77cc938d00aabe04e7ea43a3143f6fcc 348 Gene3D G3DSA:3.10.580.10 3 108 1.2E-9 T 13-10-2018 CLOST_0365 77cc938d00aabe04e7ea43a3143f6fcc 348 SUPERFAMILY SSF53448 48 341 1.62E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 Gene3D G3DSA:3.30.390.30 311 387 8.7E-7 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 292 2.4E-56 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 SUPERFAMILY SSF51905 143 301 3.75E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 4.3E-9 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 4.3E-9 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 4.3E-9 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.3E-9 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 SUPERFAMILY SSF51905 1 187 1.58E-42 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 8.8E-15 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 8.8E-15 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 8.8E-15 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 8.8E-15 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 8.8E-15 T 13-10-2018 CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 Gene3D G3DSA:3.50.50.60 34 237 1.4E-87 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0910 7ce5d8ef7b93ed044ddf09a75efda37a 390 Gene3D G3DSA:3.50.50.60 2 301 1.4E-87 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1999 a5de6e1198899f284755aea069b9b754 128 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 124 2.4E-28 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type CLOST_1999 a5de6e1198899f284755aea069b9b754 128 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 13-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CLOST_1999 a5de6e1198899f284755aea069b9b754 128 Pfam PF02082 Transcriptional regulator 1 82 2.6E-23 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type CLOST_1999 a5de6e1198899f284755aea069b9b754 128 Gene3D G3DSA:1.10.10.10 1 128 3.4E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1999 a5de6e1198899f284755aea069b9b754 128 SUPERFAMILY SSF46785 2 125 6.54E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0703 c06b581492feb16a0763082e7467e544 139 SUPERFAMILY SSF54637 6 136 4.25E-27 T 13-10-2018 IPR029069 HotDog domain superfamily CLOST_0703 c06b581492feb16a0763082e7467e544 139 Pfam PF03061 Thioesterase superfamily 18 95 1.5E-7 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CLOST_0703 c06b581492feb16a0763082e7467e544 139 Gene3D G3DSA:3.10.129.10 2 139 2.2E-29 T 13-10-2018 CLOST_0096 8d1c44c394daefda144821bc5d01d2bf 598 Pfam PF07700 Haem-NO-binding 2 159 1.9E-37 T 13-10-2018 IPR011644 Heme NO-binding GO:0020037 KEGG: 00230+4.6.1.2|Reactome: R-HSA-392154 CLOST_0096 8d1c44c394daefda144821bc5d01d2bf 598 Gene3D G3DSA:3.90.1520.10 1 184 1.5E-53 T 13-10-2018 IPR038158 H-NOX domain superfamily GO:0020037 KEGG: 00230+4.6.1.2|Reactome: R-HSA-392154 CLOST_0096 8d1c44c394daefda144821bc5d01d2bf 598 SMART SM00283 322 583 2.4E-22 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0096 8d1c44c394daefda144821bc5d01d2bf 598 SUPERFAMILY SSF111126 2 170 6.28E-33 T 13-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily CLOST_0096 8d1c44c394daefda144821bc5d01d2bf 598 SUPERFAMILY SSF58104 294 597 2.62E-55 T 13-10-2018 CLOST_0096 8d1c44c394daefda144821bc5d01d2bf 598 Gene3D G3DSA:1.10.287.950 286 597 4.7E-52 T 13-10-2018 CLOST_0096 8d1c44c394daefda144821bc5d01d2bf 598 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 397 549 4.5E-32 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_1179 e57ea548d7817e1551b4a792b1a5fcc0 599 Gene3D G3DSA:1.10.10.160 98 177 4.0E-68 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily CLOST_1179 e57ea548d7817e1551b4a792b1a5fcc0 599 Gene3D G3DSA:3.40.50.300 271 588 1.3E-51 T 13-10-2018 CLOST_1179 e57ea548d7817e1551b4a792b1a5fcc0 599 Pfam PF13361 UvrD-like helicase C-terminal domain 442 572 8.3E-22 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CLOST_1179 e57ea548d7817e1551b4a792b1a5fcc0 599 Gene3D G3DSA:3.40.50.300 4 260 4.0E-68 T 13-10-2018 CLOST_1179 e57ea548d7817e1551b4a792b1a5fcc0 599 Gene3D G3DSA:1.10.486.10 367 509 1.3E-51 T 13-10-2018 CLOST_1179 e57ea548d7817e1551b4a792b1a5fcc0 599 Pfam PF13361 UvrD-like helicase C-terminal domain 270 398 8.3E-10 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CLOST_1179 e57ea548d7817e1551b4a792b1a5fcc0 599 Pfam PF00580 UvrD/REP helicase N-terminal domain 1 259 6.7E-48 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CLOST_1179 e57ea548d7817e1551b4a792b1a5fcc0 599 SUPERFAMILY SSF52540 2 588 1.95E-102 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0292 3bdf7217c60c9000df7b218179a7963b 419 SUPERFAMILY SSF52540 281 419 6.65E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0292 3bdf7217c60c9000df7b218179a7963b 419 SUPERFAMILY SSF90123 6 323 2.62E-77 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0292 3bdf7217c60c9000df7b218179a7963b 419 Pfam PF00664 ABC transporter transmembrane region 20 291 3.0E-46 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 CLOST_0292 3bdf7217c60c9000df7b218179a7963b 419 Gene3D G3DSA:3.40.50.300 320 419 5.1E-25 T 13-10-2018 CLOST_0292 3bdf7217c60c9000df7b218179a7963b 419 Gene3D G3DSA:1.20.1560.10 2 319 1.5E-86 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0292 3bdf7217c60c9000df7b218179a7963b 419 Pfam PF00005 ABC transporter 354 419 3.1E-13 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1593 beadd1783403883e116330e3c7783dc0 393 SUPERFAMILY SSF56059 117 315 3.54E-26 T 13-10-2018 CLOST_1593 beadd1783403883e116330e3c7783dc0 393 Pfam PF07478 D-ala D-ala ligase C-terminus 139 289 1.5E-7 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_1593 beadd1783403883e116330e3c7783dc0 393 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_1593 beadd1783403883e116330e3c7783dc0 393 Gene3D G3DSA:3.30.470.20 208 326 2.0E-5 T 13-10-2018 CLOST_1593 beadd1783403883e116330e3c7783dc0 393 Gene3D G3DSA:3.30.1490.20 117 204 3.7E-10 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CLOST_2187 7b4589b6e0ec5fd37238993d99887796 102 SUPERFAMILY SSF50104 2 100 1.69E-36 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily CLOST_2187 7b4589b6e0ec5fd37238993d99887796 102 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 102 1.1E-37 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2187 7b4589b6e0ec5fd37238993d99887796 102 Gene3D G3DSA:2.30.30.30 1 101 2.3E-39 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 CLOST_2187 7b4589b6e0ec5fd37238993d99887796 102 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 13-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2187 7b4589b6e0ec5fd37238993d99887796 102 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 102 7.9E-29 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2187 7b4589b6e0ec5fd37238993d99887796 102 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 96 22.062 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2187 7b4589b6e0ec5fd37238993d99887796 102 Pfam PF00467 KOW motif 6 36 7.2E-9 T 13-10-2018 IPR005824 KOW CLOST_2187 7b4589b6e0ec5fd37238993d99887796 102 SMART SM00739 2 29 7.9E-6 T 13-10-2018 IPR005824 KOW CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 SMART SM00448 131 241 2.2E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 SUPERFAMILY SSF52172 129 262 1.57E-24 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 Pfam PF00990 Diguanylate cyclase, GGDEF domain 265 418 3.3E-40 T 13-10-2018 IPR000160 GGDEF domain CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 ProSitePatterns PS00550 Hemerythrin family signature. 490 513 - T 13-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 SUPERFAMILY SSF47188 436 559 5.89E-22 T 13-10-2018 IPR035938 Hemerythrin-like superfamily CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 Gene3D G3DSA:3.40.50.2300 122 261 1.4E-24 T 13-10-2018 CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 263 421 2.3E-47 T 13-10-2018 IPR000160 GGDEF domain CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 SMART SM00267 254 422 4.0E-48 T 13-10-2018 IPR000160 GGDEF domain CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 Gene3D G3DSA:3.30.70.270 262 427 8.9E-48 T 13-10-2018 CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 SUPERFAMILY SSF55073 270 421 1.88E-40 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 Gene3D G3DSA:1.20.120.50 432 563 3.0E-23 T 13-10-2018 IPR035938 Hemerythrin-like superfamily CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 438 560 6.9E-23 T 13-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 CLOST_0104 71af26e4093d47e52ff73cd3cbf3f33c 563 Pfam PF00072 Response regulator receiver domain 133 236 9.9E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2582 428f3878d4634e98d14fe1cbae21c00c 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.1E-12 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_2582 428f3878d4634e98d14fe1cbae21c00c 126 SUPERFAMILY SSF46785 4 78 1.43E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2582 428f3878d4634e98d14fe1cbae21c00c 126 Gene3D G3DSA:1.10.10.10 8 125 1.0E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2582 428f3878d4634e98d14fe1cbae21c00c 126 SMART SM00345 15 74 1.1E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_0053 fbf370edacd51cb77466d8d7f93943e8 270 SMART SM00729 15 230 2.4E-17 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0053 fbf370edacd51cb77466d8d7f93943e8 270 Pfam PF04055 Radical SAM superfamily 19 173 8.3E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0053 fbf370edacd51cb77466d8d7f93943e8 270 SUPERFAMILY SSF102114 20 237 1.35E-27 T 13-10-2018 CLOST_0053 fbf370edacd51cb77466d8d7f93943e8 270 Gene3D G3DSA:3.80.30.20 12 253 6.6E-13 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1449 101ef31734413f4d56b670586c0d223c 384 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 40 384 6.8E-80 T 13-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit CLOST_1449 101ef31734413f4d56b670586c0d223c 384 Gene3D G3DSA:3.40.50.11890 33 159 5.5E-31 T 13-10-2018 CLOST_1449 101ef31734413f4d56b670586c0d223c 384 Gene3D G3DSA:3.40.50.11900 240 384 1.4E-38 T 13-10-2018 CLOST_1449 101ef31734413f4d56b670586c0d223c 384 Gene3D G3DSA:1.20.1270.370 24 223 5.5E-31 T 13-10-2018 CLOST_2135 57746d4dce0830d71af69cab7693a131 191 PIRSF PIRSF035805 5 191 4.1E-64 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CLOST_2135 57746d4dce0830d71af69cab7693a131 191 Gene3D G3DSA:3.30.60.20 142 191 1.4E-24 T 13-10-2018 CLOST_2135 57746d4dce0830d71af69cab7693a131 191 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 37.193 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CLOST_2135 57746d4dce0830d71af69cab7693a131 191 Gene3D G3DSA:3.40.50.300 1 141 1.1E-54 T 13-10-2018 CLOST_2135 57746d4dce0830d71af69cab7693a131 191 SUPERFAMILY SSF52540 8 142 3.05E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2135 57746d4dce0830d71af69cab7693a131 191 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 13-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CLOST_2135 57746d4dce0830d71af69cab7693a131 191 Pfam PF00265 Thymidine kinase 9 187 3.1E-57 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CLOST_2135 57746d4dce0830d71af69cab7693a131 191 SUPERFAMILY SSF57716 142 189 7.13E-16 T 13-10-2018 CLOST_1231 9e1a8011100f9d6a6f569a4025bdba38 77 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 1.3E-30 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CLOST_1231 9e1a8011100f9d6a6f569a4025bdba38 77 Gene3D G3DSA:2.30.30.100 1 73 4.8E-31 T 13-10-2018 CLOST_1231 9e1a8011100f9d6a6f569a4025bdba38 77 SUPERFAMILY SSF50182 6 65 1.53E-23 T 13-10-2018 IPR010920 LSM domain superfamily CLOST_1231 9e1a8011100f9d6a6f569a4025bdba38 77 Pfam PF17209 Hfq protein 7 67 3.3E-31 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CLOST_1231 9e1a8011100f9d6a6f569a4025bdba38 77 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 28.439 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CLOST_2539 4f03f1804728d0817d54aad037506b6f 290 PIRSF PIRSF016184 1 287 8.1E-82 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CLOST_2539 4f03f1804728d0817d54aad037506b6f 290 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 283 1.2E-71 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CLOST_2539 4f03f1804728d0817d54aad037506b6f 290 SUPERFAMILY SSF54506 2 282 1.96E-70 T 13-10-2018 CLOST_2539 4f03f1804728d0817d54aad037506b6f 290 Gene3D G3DSA:3.10.310.10 1 122 3.0E-40 T 13-10-2018 CLOST_2539 4f03f1804728d0817d54aad037506b6f 290 Gene3D G3DSA:3.10.310.10 123 277 2.4E-50 T 13-10-2018 CLOST_2539 4f03f1804728d0817d54aad037506b6f 290 Pfam PF02567 Phenazine biosynthesis-like protein 8 280 1.6E-65 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 SUPERFAMILY SSF55973 119 241 3.1E-54 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 SUPERFAMILY SSF55973 242 392 5.1E-69 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 4 390 3.9E-187 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 PIRSF PIRSF000497 1 393 6.8E-180 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 3 100 3.3E-45 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 392 58.917 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 268 276 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 242 380 4.2E-70 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 Pfam PF02772 S-adenosylmethionine synthetase, central domain 124 240 2.2E-51 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 SUPERFAMILY SSF55973 2 108 4.71E-49 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 Gene3D G3DSA:3.30.300.10 10 279 5.0E-181 T 13-10-2018 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 Gene3D G3DSA:3.30.300.10 101 383 5.0E-181 T 13-10-2018 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 Gene3D G3DSA:3.30.300.10 4 242 5.0E-181 T 13-10-2018 CLOST_2356 f3da4546a7507760ee3a8cf8b9926c28 394 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 125 135 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 Gene3D G3DSA:3.40.47.10 1 254 3.4E-94 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 SMART SM00825 Beta-ketoacyl synthase 5 412 1.5E-14 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 SUPERFAMILY SSF53901 3 250 5.09E-78 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 SUPERFAMILY SSF53901 213 410 9.61E-72 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 1.2E-59 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 7.6E-40 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 408 7.5E-192 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 Gene3D G3DSA:3.40.47.10 255 399 1.3E-54 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_0899 55a23bcbabfaf585c6085ff93413bd83 413 PIRSF PIRSF000447 1 412 1.1E-182 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 PIRSF PIRSF005719 1 1176 4.4E-273 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1170 22.159 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 Gene3D G3DSA:3.40.50.300 1016 1177 5.1E-49 T 13-10-2018 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 SUPERFAMILY SSF52540 1 1154 6.44E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 SUPERFAMILY SSF52540 382 1171 8.63E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 SMART SM00968 520 630 4.0E-39 T 13-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1168 2.6E-301 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 285 1.2E-29 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 Gene3D G3DSA:1.20.1060.20 481 590 2.0E-34 T 13-10-2018 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 SUPERFAMILY SSF75553 486 678 7.98E-50 T 13-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 Gene3D G3DSA:3.40.50.300 1 227 1.7E-58 T 13-10-2018 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 Gene3D G3DSA:3.30.70.1620 591 658 5.8E-23 T 13-10-2018 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 629 1.9E-31 T 13-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CLOST_1583 8c42068714c5e22f0d47e8ce511232c3 1177 Pfam PF02463 RecF/RecN/SMC N terminal domain 705 1161 2.8E-27 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal CLOST_2468 937cb928d9fc5c29ae87b8261270c679 448 Pfam PF04055 Radical SAM superfamily 163 323 1.0E-16 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_2468 937cb928d9fc5c29ae87b8261270c679 448 Pfam PF02310 B12 binding domain 40 120 3.3E-7 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_2468 937cb928d9fc5c29ae87b8261270c679 448 Gene3D G3DSA:3.40.50.280 19 137 1.2E-9 T 13-10-2018 CLOST_2468 937cb928d9fc5c29ae87b8261270c679 448 SMART SM00729 159 365 3.8E-22 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_2468 937cb928d9fc5c29ae87b8261270c679 448 Gene3D G3DSA:3.80.30.20 159 362 4.3E-21 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_2468 937cb928d9fc5c29ae87b8261270c679 448 Pfam PF13282 Domain of unknown function (DUF4070) 342 403 2.1E-5 T 13-10-2018 IPR025274 Domain of unknown function DUF4070 CLOST_2468 937cb928d9fc5c29ae87b8261270c679 448 SUPERFAMILY SSF102114 144 395 3.14E-36 T 13-10-2018 CLOST_0692 e63e3f6223f988fe02177eff548b29ae 188 Gene3D G3DSA:1.10.1760.20 1 187 6.1E-27 T 13-10-2018 CLOST_0692 e63e3f6223f988fe02177eff548b29ae 188 Pfam PF12822 ECF transporter, substrate-specific component 13 171 2.8E-11 T 13-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CLOST_1406 435a4ee733ab905656d3dbb33699b092 200 SUPERFAMILY SSF52540 1 190 1.26E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1406 435a4ee733ab905656d3dbb33699b092 200 Gene3D G3DSA:3.40.50.300 1 199 1.5E-69 T 13-10-2018 CLOST_1406 435a4ee733ab905656d3dbb33699b092 200 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 24.519 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CLOST_1406 435a4ee733ab905656d3dbb33699b092 200 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 2 187 1.1E-56 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CLOST_1406 435a4ee733ab905656d3dbb33699b092 200 Pfam PF01121 Dephospho-CoA kinase 1 180 1.0E-53 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 394 131.271 T 13-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 SMART SM00981 73 166 5.9E-15 T 13-10-2018 IPR004114 THUMP domain GO:0003723 CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 Gene3D G3DSA:3.40.50.620 177 394 1.3E-68 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 373 1.7E-66 T 13-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 375 8.2E-107 T 13-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 Gene3D G3DSA:3.30.2130.30 1 175 2.5E-51 T 13-10-2018 CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 SUPERFAMILY SSF52402 179 383 8.38E-47 T 13-10-2018 CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 SUPERFAMILY SSF143437 2 175 1.15E-43 T 13-10-2018 CLOST_1444 7f69ade0e8f19b97e56d8a83058976da 394 Pfam PF02926 THUMP domain 41 164 4.2E-16 T 13-10-2018 IPR004114 THUMP domain GO:0003723 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 233 1.4E-114 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 Gene3D G3DSA:3.90.950.10 245 443 4.3E-71 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 Gene3D G3DSA:3.30.230.70 7 236 3.5E-64 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 SUPERFAMILY SSF54211 7 178 2.83E-40 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 SUPERFAMILY SSF55666 150 242 3.27E-25 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 248 439 1.4E-61 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 Hamap MF_00564 Ribonuclease PH [rph]. 8 234 44.495 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 Pfam PF01725 Ham1 family 250 437 4.3E-54 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 ProSitePatterns PS01277 Ribonuclease PH signature. 113 125 - T 13-10-2018 IPR018336 Ribonuclease PH, conserved site CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 SUPERFAMILY SSF52972 245 441 1.91E-66 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 Pfam PF03725 3' exoribonuclease family, domain 2 155 220 2.4E-13 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 Hamap MF_01405 dITP/XTP pyrophosphatase. 247 441 47.698 T 13-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 CLOST_0588 9b905c7dca1f932a71e5524ff9be0cbc 443 Pfam PF01138 3' exoribonuclease family, domain 1 8 137 2.8E-21 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CLOST_0244 56c252c654ef9b8bc42b3b4a6c09a655 200 Pfam PF03861 ANTAR domain 140 193 1.6E-19 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 CLOST_0244 56c252c654ef9b8bc42b3b4a6c09a655 200 Gene3D G3DSA:3.40.50.2300 1 139 1.1E-32 T 13-10-2018 CLOST_0244 56c252c654ef9b8bc42b3b4a6c09a655 200 Gene3D G3DSA:1.10.10.10 140 199 1.5E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0244 56c252c654ef9b8bc42b3b4a6c09a655 200 Pfam PF00072 Response regulator receiver domain 12 122 7.2E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0244 56c252c654ef9b8bc42b3b4a6c09a655 200 SUPERFAMILY SSF52172 5 193 2.56E-51 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0244 56c252c654ef9b8bc42b3b4a6c09a655 200 SMART SM01012 138 193 2.6E-21 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 CLOST_0244 56c252c654ef9b8bc42b3b4a6c09a655 200 PIRSF PIRSF036382 1 199 6.8E-68 T 13-10-2018 IPR008327 Signal transduction response regulator, antiterminator CLOST_0244 56c252c654ef9b8bc42b3b4a6c09a655 200 SMART SM00448 10 122 1.8E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 SUPERFAMILY SSF51717 307 558 9.42E-55 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 SUPERFAMILY SSF52242 634 765 4.58E-37 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 Gene3D G3DSA:3.20.20.330 1 288 5.1E-78 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 Gene3D G3DSA:3.40.50.280 647 770 2.2E-39 T 13-10-2018 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 SUPERFAMILY SSF82282 3 350 6.67E-79 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 Pfam PF02574 Homocysteine S-methyltransferase 4 274 2.3E-48 T 13-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 Pfam PF00809 Pterin binding enzyme 328 531 5.4E-24 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 Gene3D G3DSA:3.20.20.20 294 561 5.7E-72 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0144 66250ed8fb3a87d188e00c48e36879be 770 Pfam PF02310 B12 binding domain 649 758 1.3E-23 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0630 6f0eecc5aa338fb93a96a63986004434 224 SUPERFAMILY SSF51206 5 148 8.51E-22 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like CLOST_0630 6f0eecc5aa338fb93a96a63986004434 224 Pfam PF13545 Crp-like helix-turn-helix domain 171 220 3.5E-9 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_0630 6f0eecc5aa338fb93a96a63986004434 224 Pfam PF00027 Cyclic nucleotide-binding domain 38 125 5.3E-9 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_0630 6f0eecc5aa338fb93a96a63986004434 224 SUPERFAMILY SSF46785 169 221 1.3E-8 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0630 6f0eecc5aa338fb93a96a63986004434 224 Gene3D G3DSA:2.60.120.1460 3 223 1.5E-48 T 13-10-2018 CLOST_2506 f61d9e2864f6665395cc0863d61c3bb6 321 SUPERFAMILY SSF51658 19 236 3.51E-20 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily CLOST_2506 f61d9e2864f6665395cc0863d61c3bb6 321 Pfam PF01261 Xylose isomerase-like TIM barrel 74 235 1.8E-11 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CLOST_2506 f61d9e2864f6665395cc0863d61c3bb6 321 Gene3D G3DSA:3.20.20.150 17 311 5.9E-21 T 13-10-2018 CLOST_1633 2d01912d01937f2aa4e2e1397955e486 306 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 299 3.7E-94 T 13-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CLOST_1633 2d01912d01937f2aa4e2e1397955e486 306 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1633 2d01912d01937f2aa4e2e1397955e486 306 Gene3D G3DSA:3.40.50.300 1 241 1.3E-71 T 13-10-2018 CLOST_1633 2d01912d01937f2aa4e2e1397955e486 306 Pfam PF00005 ABC transporter 21 163 3.0E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1633 2d01912d01937f2aa4e2e1397955e486 306 SMART SM00382 29 211 1.2E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1633 2d01912d01937f2aa4e2e1397955e486 306 SUPERFAMILY SSF52540 3 225 6.85E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 Pfam PF07702 UTRA domain 94 232 2.5E-36 T 13-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 7.6E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 7.6E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.1E-18 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 SMART SM00345 13 72 2.0E-18 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 Gene3D G3DSA:1.10.10.10 8 76 1.5E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 SMART SM00866 93 233 1.3E-34 T 13-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 SUPERFAMILY SSF64288 60 238 3.77E-49 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 Gene3D G3DSA:3.40.1410.10 77 239 1.0E-47 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily CLOST_1200 31d6b1f18bc069a76235b68af3b4f173 242 SUPERFAMILY SSF46785 8 83 1.17E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2257 b570292b27c8e49f3e9bad35e23fe6cf 783 Gene3D G3DSA:3.30.1620.10 243 350 1.6E-214 T 13-10-2018 CLOST_2257 b570292b27c8e49f3e9bad35e23fe6cf 783 TIGRFAM TIGR02505 RTPR: ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent 117 783 7.4E-111 T 13-10-2018 IPR013345 Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0006260|GO:0008998|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CLOST_2257 b570292b27c8e49f3e9bad35e23fe6cf 783 Gene3D G3DSA:3.20.70.20 106 732 1.6E-214 T 13-10-2018 CLOST_2257 b570292b27c8e49f3e9bad35e23fe6cf 783 Gene3D G3DSA:3.90.1390.10 614 751 1.6E-214 T 13-10-2018 CLOST_2257 b570292b27c8e49f3e9bad35e23fe6cf 783 Pfam PF03477 ATP cone domain 2 89 1.0E-18 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CLOST_2257 b570292b27c8e49f3e9bad35e23fe6cf 783 SUPERFAMILY SSF51998 113 748 7.69E-127 T 13-10-2018 CLOST_2257 b570292b27c8e49f3e9bad35e23fe6cf 783 Pfam PF02867 Ribonucleotide reductase, barrel domain 431 583 1.1E-8 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CLOST_1148 bc5cab9fa2f7d12864f471ffb7117166 142 Gene3D G3DSA:1.10.10.10 1 87 8.8E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1148 bc5cab9fa2f7d12864f471ffb7117166 142 SUPERFAMILY SSF46785 10 135 4.82E-30 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1148 bc5cab9fa2f7d12864f471ffb7117166 142 Gene3D G3DSA:3.30.1490.190 89 142 2.3E-9 T 13-10-2018 CLOST_1148 bc5cab9fa2f7d12864f471ffb7117166 142 Pfam PF01475 Ferric uptake regulator family 16 129 7.2E-27 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 SUPERFAMILY SSF53335 59 243 2.66E-22 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 Gene3D G3DSA:3.10.290.10 1 61 3.1E-20 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 SMART SM00363 3 68 2.3E-9 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 PIRSF PIRSF005578 1 262 2.9E-102 T 13-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 SUPERFAMILY SSF55174 3 68 7.21E-11 T 13-10-2018 CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 Gene3D G3DSA:3.40.50.150 62 266 1.7E-82 T 13-10-2018 CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 Pfam PF01728 FtsJ-like methyltransferase 59 242 4.1E-19 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 4 237 8.1E-85 T 13-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CLOST_1342 ea7aa885e8d89497905cc7286ff8a47d 266 Pfam PF01479 S4 domain 4 47 1.7E-8 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2096 f7039c66e22f6d4df59e98487c7488ad 149 SUPERFAMILY SSF56524 25 148 6.67E-9 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 CLOST_2096 f7039c66e22f6d4df59e98487c7488ad 149 Pfam PF00174 Oxidoreductase molybdopterin binding domain 49 148 1.3E-5 T 13-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CLOST_0685 aa1612293833dfe1309516000e862e87 364 Gene3D G3DSA:3.40.50.2300 150 323 6.2E-62 T 13-10-2018 CLOST_0685 aa1612293833dfe1309516000e862e87 364 Pfam PF13407 Periplasmic binding protein domain 61 310 1.7E-26 T 13-10-2018 IPR025997 Periplasmic binding protein CLOST_0685 aa1612293833dfe1309516000e862e87 364 Gene3D G3DSA:3.40.50.2300 54 317 6.2E-62 T 13-10-2018 CLOST_0685 aa1612293833dfe1309516000e862e87 364 SUPERFAMILY SSF53822 50 326 9.24E-40 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 168 321 1.1E-36 T 13-10-2018 IPR000160 GGDEF domain CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 Pfam PF00989 PAS fold 52 156 8.9E-8 T 13-10-2018 IPR013767 PAS fold GO:0006355 CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 SMART SM00091 48 112 0.0052 T 13-10-2018 IPR000014 PAS domain CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 Pfam PF00990 Diguanylate cyclase, GGDEF domain 170 318 1.3E-35 T 13-10-2018 IPR000160 GGDEF domain CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 Pfam PF13487 HD domain 391 453 5.1E-19 T 13-10-2018 CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 SUPERFAMILY SSF109604 330 499 4.0E-34 T 13-10-2018 CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 SUPERFAMILY SSF55073 175 318 2.43E-34 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 Gene3D G3DSA:1.10.3210.10 320 502 6.1E-63 T 13-10-2018 CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 49 166 2.3E-13 T 13-10-2018 IPR000014 PAS domain CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 Gene3D G3DSA:3.30.450.20 35 157 2.2E-14 T 13-10-2018 CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 SUPERFAMILY SSF55785 53 160 5.41E-13 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 SMART SM00267 159 324 8.4E-43 T 13-10-2018 IPR000160 GGDEF domain CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 SMART SM00471 336 471 1.5E-6 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_2375 67472b3730f8c1de227c6db5c1c60448 502 Gene3D G3DSA:3.30.70.270 158 319 1.3E-39 T 13-10-2018 CLOST_0209 960766b29427b23f51e7475df729ccf1 400 Pfam PF13173 AAA domain 19 150 3.9E-38 T 13-10-2018 CLOST_0209 960766b29427b23f51e7475df729ccf1 400 Pfam PF13635 Domain of unknown function (DUF4143) 202 346 1.1E-9 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 CLOST_0209 960766b29427b23f51e7475df729ccf1 400 SUPERFAMILY SSF52540 3 204 8.27E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 SUPERFAMILY SSF56281 6 282 2.8E-45 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 SUPERFAMILY SSF52218 251 396 1.46E-34 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 SMART SM00849 36 203 3.1E-23 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 ProSitePatterns PS00201 Flavodoxin signature. 255 271 - T 13-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 Gene3D G3DSA:3.40.50.360 248 399 3.4E-40 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 Gene3D G3DSA:3.60.15.10 2 246 1.5E-94 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 Pfam PF00753 Metallo-beta-lactamase superfamily 38 226 1.0E-4 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 PIRSF PIRSF005243 1 399 4.8E-134 T 13-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 CLOST_0656 bb8f8046305880f9f75041508c2fa598 399 Pfam PF00258 Flavodoxin 255 385 3.7E-11 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CLOST_0418 56afb2a11def6cb03d4299f1a8b6c836 417 Gene3D G3DSA:3.90.1150.10 7 390 9.2E-152 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0418 56afb2a11def6cb03d4299f1a8b6c836 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 412 42.116 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CLOST_0418 56afb2a11def6cb03d4299f1a8b6c836 417 SUPERFAMILY SSF53383 4 412 8.16E-146 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0418 56afb2a11def6cb03d4299f1a8b6c836 417 Gene3D G3DSA:3.40.640.10 34 284 9.2E-152 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0418 56afb2a11def6cb03d4299f1a8b6c836 417 PIRSF PIRSF000412 1 413 9.2E-133 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CLOST_0418 56afb2a11def6cb03d4299f1a8b6c836 417 Pfam PF00464 Serine hydroxymethyltransferase 7 381 7.1E-134 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 Gene3D G3DSA:3.40.710.10 22 292 6.7E-90 T 13-10-2018 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 109 126 8.6E-14 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 61 72 8.6E-14 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 136 149 8.6E-14 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 30 269 6.6E-58 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 Gene3D G3DSA:2.60.410.10 293 375 3.8E-11 T 13-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 SMART SM00936 288 376 1.1E-15 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 SUPERFAMILY SSF69189 280 369 2.75E-12 T 13-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 288 375 2.4E-10 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CLOST_1362 66f9ea2c5f1c76432387959c47837c9c 433 SUPERFAMILY SSF56601 6 288 4.23E-71 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like CLOST_1871 9a3405013ae767e79738ea29db722cf4 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 44 52 3.0E-16 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 CLOST_1871 9a3405013ae767e79738ea29db722cf4 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 88 103 3.0E-16 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 CLOST_1871 9a3405013ae767e79738ea29db722cf4 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 122 138 3.0E-16 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 CLOST_1871 9a3405013ae767e79738ea29db722cf4 150 ProSitePatterns PS00855 Signal peptidases II signature. 91 103 - T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 CLOST_1871 9a3405013ae767e79738ea29db722cf4 150 Pfam PF01252 Signal peptidase (SPase) II 6 140 1.2E-36 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 CLOST_1871 9a3405013ae767e79738ea29db722cf4 150 TIGRFAM TIGR00077 lspA: signal peptidase II 2 141 3.4E-33 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 CLOST_1871 9a3405013ae767e79738ea29db722cf4 150 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 147 15.335 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 SUPERFAMILY SSF52954 327 418 2.45E-25 T 13-10-2018 CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 SUPERFAMILY SSF55681 4 319 1.74E-99 T 13-10-2018 CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 408 8.8E-155 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 Pfam PF03129 Anticodon binding domain 329 418 9.5E-16 T 13-10-2018 IPR004154 Anticodon-binding CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 PIRSF PIRSF001549 1 419 8.4E-130 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 418 34.032 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 Gene3D G3DSA:3.40.50.800 327 420 1.3E-25 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 Pfam PF13393 Histidyl-tRNA synthetase 8 311 4.8E-45 T 13-10-2018 CLOST_1301 e351edc31ab8b8c620f3631372cee975 420 Gene3D G3DSA:3.30.930.10 1 321 4.8E-118 T 13-10-2018 CLOST_0081 2481def1063a5cac8e214b762864b2c5 595 SUPERFAMILY SSF53067 183 398 1.0E-4 T 13-10-2018 CLOST_0081 2481def1063a5cac8e214b762864b2c5 595 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 82 9.1E-11 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CLOST_0081 2481def1063a5cac8e214b762864b2c5 595 Pfam PF14574 Domain of unknown function (DUF4445) 182 592 1.2E-146 T 13-10-2018 IPR027980 Protein of unknown function DUF4445 CLOST_0081 2481def1063a5cac8e214b762864b2c5 595 SUPERFAMILY SSF54292 2 95 1.62E-23 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 CLOST_0081 2481def1063a5cac8e214b762864b2c5 595 Gene3D G3DSA:3.30.420.480 180 359 1.1E-55 T 13-10-2018 CLOST_0081 2481def1063a5cac8e214b762864b2c5 595 Gene3D G3DSA:3.10.20.30 4 94 8.4E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily CLOST_2084 efb71dffbecd120b15a8d2ca6786d2ae 296 Gene3D G3DSA:3.30.70.3040 59 155 7.3E-5 T 13-10-2018 CLOST_2084 efb71dffbecd120b15a8d2ca6786d2ae 296 Pfam PF02687 FtsX-like permease family 198 295 1.5E-9 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CLOST_2084 efb71dffbecd120b15a8d2ca6786d2ae 296 PIRSF PIRSF003097 1 296 1.4E-78 T 13-10-2018 IPR004513 Cell division protein FtsX GO:0016021 CLOST_2419 a0a8da5f8102644022f7a5d58964d751 206 Pfam PF12672 Protein of unknown function (DUF3793) 30 202 9.5E-41 T 13-10-2018 IPR024523 Protein of unknown function DUF3793 CLOST_2086 ae980196cb6581c946201b86bb1ade8c 147 Pfam PF00005 ABC transporter 18 146 4.1E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2086 ae980196cb6581c946201b86bb1ade8c 147 Gene3D G3DSA:3.40.50.300 1 147 5.7E-45 T 13-10-2018 CLOST_2086 ae980196cb6581c946201b86bb1ade8c 147 SUPERFAMILY SSF52540 1 147 2.38E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0675 43975b1fe0c032ec592cfc7e7c4da4ca 107 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 4 74 0.003 T 13-10-2018 CLOST_0675 43975b1fe0c032ec592cfc7e7c4da4ca 107 Gene3D G3DSA:3.30.70.1710 2 105 7.1E-17 T 13-10-2018 CLOST_0675 43975b1fe0c032ec592cfc7e7c4da4ca 107 Pfam PF00936 BMC domain 5 84 2.3E-15 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0675 43975b1fe0c032ec592cfc7e7c4da4ca 107 SMART SM00877 4 91 2.1E-7 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0675 43975b1fe0c032ec592cfc7e7c4da4ca 107 SUPERFAMILY SSF143414 4 101 6.28E-14 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 Gene3D G3DSA:3.90.640.10 182 255 8.1E-130 T 13-10-2018 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 3 332 7.6E-147 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 Gene3D G3DSA:3.30.420.40 7 323 8.1E-130 T 13-10-2018 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 SUPERFAMILY SSF53067 3 144 1.23E-41 T 13-10-2018 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 Pfam PF06723 MreB/Mbl protein 5 332 1.6E-147 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 Gene3D G3DSA:3.30.420.40 150 313 8.1E-130 T 13-10-2018 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 SUPERFAMILY SSF53067 146 324 3.63E-48 T 13-10-2018 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 4.0E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 4.0E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 296 322 4.0E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 183 203 4.0E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CLOST_2363 62c54f288d836cbf63806e8267f060bd 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 128 147 4.0E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CLOST_1478 95296e741e01b69eaeb6a575f700fe61 179 Gene3D G3DSA:2.60.120.10 74 174 8.1E-22 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_1478 95296e741e01b69eaeb6a575f700fe61 179 SMART SM00530 6 61 1.4E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1478 95296e741e01b69eaeb6a575f700fe61 179 Pfam PF01381 Helix-turn-helix 7 60 5.4E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1478 95296e741e01b69eaeb6a575f700fe61 179 SUPERFAMILY SSF47413 1 67 3.1E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_1478 95296e741e01b69eaeb6a575f700fe61 179 Gene3D G3DSA:1.10.260.40 1 69 1.6E-18 T 13-10-2018 CLOST_1478 95296e741e01b69eaeb6a575f700fe61 179 Pfam PF07883 Cupin domain 105 173 3.8E-18 T 13-10-2018 IPR013096 Cupin 2, conserved barrel CLOST_1478 95296e741e01b69eaeb6a575f700fe61 179 SUPERFAMILY SSF51182 54 179 3.67E-31 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0577 0c8ee591ff8a2bb23296b68f23f82c5f 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 215 231 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CLOST_0577 0c8ee591ff8a2bb23296b68f23f82c5f 313 Gene3D G3DSA:3.40.50.720 95 280 4.8E-79 T 13-10-2018 CLOST_0577 0c8ee591ff8a2bb23296b68f23f82c5f 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 275 2.1E-50 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CLOST_0577 0c8ee591ff8a2bb23296b68f23f82c5f 313 SUPERFAMILY SSF51735 96 277 3.35E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0577 0c8ee591ff8a2bb23296b68f23f82c5f 313 SUPERFAMILY SSF52283 1 124 1.48E-13 T 13-10-2018 CLOST_0577 0c8ee591ff8a2bb23296b68f23f82c5f 313 Gene3D G3DSA:3.40.50.720 39 305 4.8E-79 T 13-10-2018 CLOST_0577 0c8ee591ff8a2bb23296b68f23f82c5f 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 307 8.9E-9 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 CLOST_1700 0c09198d3d1f86eee7c11cfa5084deab 242 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 12 239 2.8E-88 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CLOST_1700 0c09198d3d1f86eee7c11cfa5084deab 242 SUPERFAMILY SSF64005 9 235 3.66E-87 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 CLOST_1700 0c09198d3d1f86eee7c11cfa5084deab 242 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 13-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 CLOST_1700 0c09198d3d1f86eee7c11cfa5084deab 242 Pfam PF01255 Putative undecaprenyl diphosphate synthase 19 239 5.5E-80 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CLOST_1700 0c09198d3d1f86eee7c11cfa5084deab 242 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 12 240 40.341 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CLOST_1700 0c09198d3d1f86eee7c11cfa5084deab 242 Gene3D G3DSA:3.40.1180.10 2 241 4.5E-93 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 CLOST_0813 b336b515ef44c7bc5a3d0c5725c758cc 90 Pfam PF01527 Transposase 3 82 8.6E-9 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 CLOST_0813 b336b515ef44c7bc5a3d0c5725c758cc 90 SUPERFAMILY SSF46689 6 89 1.97E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_0813 b336b515ef44c7bc5a3d0c5725c758cc 90 Gene3D G3DSA:1.10.10.60 9 88 3.8E-8 T 13-10-2018 CLOST_1761 373e0a492250a62b0c09a66086ddcfce 197 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 73 89 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CLOST_1761 373e0a492250a62b0c09a66086ddcfce 197 Gene3D G3DSA:3.30.1130.10 63 196 4.6E-58 T 13-10-2018 CLOST_1761 373e0a492250a62b0c09a66086ddcfce 197 Gene3D G3DSA:1.10.286.10 2 61 3.3E-24 T 13-10-2018 CLOST_1761 373e0a492250a62b0c09a66086ddcfce 197 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 12 195 42.28 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CLOST_1761 373e0a492250a62b0c09a66086ddcfce 197 SUPERFAMILY SSF55620 9 195 4.82E-80 T 13-10-2018 CLOST_1761 373e0a492250a62b0c09a66086ddcfce 197 Pfam PF01227 GTP cyclohydrolase I 16 194 9.5E-78 T 13-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CLOST_1761 373e0a492250a62b0c09a66086ddcfce 197 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 16 194 2.2E-76 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CLOST_0768 4b6ee69d706bf17b61634b2f9ec915a3 348 Pfam PF01758 Sodium Bile acid symporter family 54 251 6.6E-46 T 13-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CLOST_0768 4b6ee69d706bf17b61634b2f9ec915a3 348 Gene3D G3DSA:1.20.1530.20 3 340 7.0E-29 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily CLOST_0768 4b6ee69d706bf17b61634b2f9ec915a3 348 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 9 339 1.9E-117 T 13-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CLOST_0768 4b6ee69d706bf17b61634b2f9ec915a3 348 PIRSF PIRSF005508 1 348 1.9E-130 T 13-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 687 905 1.8E-77 T 13-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 340 594 3.9E-33 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 25 275 4.3E-19 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 920 1238 3.2E-54 T 13-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 Gene3D G3DSA:3.30.420.40 116 260 2.3E-67 T 13-10-2018 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 Gene3D G3DSA:3.30.420.40 340 594 3.8E-80 T 13-10-2018 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 Gene3D G3DSA:3.30.420.40 434 577 3.8E-80 T 13-10-2018 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 340 593 2.3E-38 T 13-10-2018 IPR008275 CoA enzyme activase CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 SUPERFAMILY SSF53067 24 275 3.56E-52 T 13-10-2018 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 Gene3D G3DSA:3.30.420.40 25 275 2.3E-67 T 13-10-2018 CLOST_1071 2585f5c7a6eb52b076ed69137947571b 1448 SUPERFAMILY SSF53067 339 594 1.14E-49 T 13-10-2018 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 225 32.024 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 SUPERFAMILY SSF69065 5 164 2.27E-49 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 SMART SM00535 20 155 1.3E-51 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 Pfam PF00035 Double-stranded RNA binding motif 162 227 1.4E-16 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 Gene3D G3DSA:1.10.1520.10 1 155 3.4E-48 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 SUPERFAMILY SSF54768 115 228 8.33E-24 T 13-10-2018 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 Pfam PF14622 Ribonuclease-III-like 20 146 6.8E-43 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 Gene3D G3DSA:3.30.160.20 161 227 1.1E-22 T 13-10-2018 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 ProSitePatterns PS00517 Ribonuclease III family signature. 44 52 - T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 SMART SM00358 162 229 3.1E-21 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain CLOST_1585 05c2229dfbc3e19ebea3c218d56572d8 229 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 227 5.6E-83 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CLOST_1939 f06216e21faad5cb86266d7b2536d5d4 182 Gene3D G3DSA:3.60.21.10 1 182 1.5E-54 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like CLOST_1939 f06216e21faad5cb86266d7b2536d5d4 182 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 162 7.2E-26 T 13-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CLOST_1939 f06216e21faad5cb86266d7b2536d5d4 182 SUPERFAMILY SSF56300 1 163 2.04E-36 T 13-10-2018 CLOST_1939 f06216e21faad5cb86266d7b2536d5d4 182 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 164 2.2E-29 T 13-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Pfam PF08264 Anticodon-binding domain of tRNA 650 762 2.9E-18 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 SUPERFAMILY SSF52374 3 627 4.12E-139 T 13-10-2018 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Gene3D G3DSA:1.10.730.10 621 718 2.4E-12 T 13-10-2018 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 800 21.553 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Gene3D G3DSA:2.30.210.10 575 591 8.8E-236 T 13-10-2018 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Gene3D G3DSA:3.90.740.10 227 413 8.8E-236 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 800 9.9E-303 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Pfam PF09334 tRNA synthetases class I (M) 40 187 5.4E-20 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Gene3D G3DSA:3.40.50.620 33 574 8.8E-236 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 415 605 8.3E-20 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 53 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 SUPERFAMILY SSF47323 622 800 8.6E-36 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 SUPERFAMILY SSF50677 225 413 4.29E-45 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 220 401 1.4E-60 T 13-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 1.6E-43 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 1.6E-43 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 1.6E-43 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 PRINTS PR00985 Leucyl-tRNA synthetase signature 560 570 1.6E-43 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 PRINTS PR00985 Leucyl-tRNA synthetase signature 214 233 1.6E-43 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 PRINTS PR00985 Leucyl-tRNA synthetase signature 527 549 1.6E-43 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 PRINTS PR00985 Leucyl-tRNA synthetase signature 488 506 1.6E-43 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CLOST_2043 08c3405061c13af9bec3c00f6bb0505e 800 Gene3D G3DSA:3.10.20.590 739 800 2.6E-21 T 13-10-2018 CLOST_1331 20b321b86887f5dbe8cf01eae5fca7ad 338 Gene3D G3DSA:3.30.160.60 307 338 4.6E-10 T 13-10-2018 CLOST_1331 20b321b86887f5dbe8cf01eae5fca7ad 338 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 8 338 33.137 T 13-10-2018 IPR003770 Endolytic murein transglycosylase CLOST_1331 20b321b86887f5dbe8cf01eae5fca7ad 338 Gene3D G3DSA:1.10.8.1150 37 107 2.1E-20 T 13-10-2018 CLOST_1331 20b321b86887f5dbe8cf01eae5fca7ad 338 Pfam PF02618 YceG-like family 42 333 7.9E-83 T 13-10-2018 IPR003770 Endolytic murein transglycosylase CLOST_1331 20b321b86887f5dbe8cf01eae5fca7ad 338 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 3 336 2.5E-84 T 13-10-2018 IPR003770 Endolytic murein transglycosylase CLOST_0464 863120dd098324e091f27d9587a99ada 651 Hamap MF_01228 Methionine--tRNA ligase [metG]. 2 509 48.735 T 13-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 510 7.7E-164 T 13-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 Gene3D G3DSA:3.40.50.620 6 335 2.5E-146 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0464 863120dd098324e091f27d9587a99ada 651 Gene3D G3DSA:2.40.50.140 540 650 3.4E-37 T 13-10-2018 CLOST_0464 863120dd098324e091f27d9587a99ada 651 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 524 650 4.0E-38 T 13-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 SUPERFAMILY SSF47323 352 563 1.08E-42 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0464 863120dd098324e091f27d9587a99ada 651 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 3 140 2.8E-14 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0464 863120dd098324e091f27d9587a99ada 651 Gene3D G3DSA:2.170.220.10 117 227 2.5E-146 T 13-10-2018 CLOST_0464 863120dd098324e091f27d9587a99ada 651 SUPERFAMILY SSF52374 3 353 6.76E-107 T 13-10-2018 CLOST_0464 863120dd098324e091f27d9587a99ada 651 SUPERFAMILY SSF50249 549 649 2.45E-33 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_0464 863120dd098324e091f27d9587a99ada 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 6.1E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 350 361 6.1E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 273 6.1E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 225 236 6.1E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 6.1E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 6.1E-32 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CLOST_0464 863120dd098324e091f27d9587a99ada 651 Pfam PF08264 Anticodon-binding domain of tRNA 396 482 7.7E-7 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 CLOST_0464 863120dd098324e091f27d9587a99ada 651 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0464 863120dd098324e091f27d9587a99ada 651 Gene3D G3DSA:1.10.730.10 340 512 3.2E-51 T 13-10-2018 CLOST_0464 863120dd098324e091f27d9587a99ada 651 Pfam PF01588 Putative tRNA binding domain 556 641 4.4E-30 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CLOST_0464 863120dd098324e091f27d9587a99ada 651 Pfam PF09334 tRNA synthetases class I (M) 153 362 8.6E-65 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1177 b4a0de8d860a2da5df5979356c62852b 144 Gene3D G3DSA:1.20.120.20 52 143 1.9E-5 T 13-10-2018 CLOST_1177 b4a0de8d860a2da5df5979356c62852b 144 SUPERFAMILY SSF58113 53 143 5.1E-6 T 13-10-2018 CLOST_0764 d0b5645b6c24e0192b0f5a08f61be956 116 Gene3D G3DSA:1.10.10.10 1 89 4.0E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0764 d0b5645b6c24e0192b0f5a08f61be956 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 2.4E-17 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0764 d0b5645b6c24e0192b0f5a08f61be956 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 2.4E-17 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0764 d0b5645b6c24e0192b0f5a08f61be956 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 38 2.4E-17 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0764 d0b5645b6c24e0192b0f5a08f61be956 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 2.4E-17 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0764 d0b5645b6c24e0192b0f5a08f61be956 116 SUPERFAMILY SSF46785 1 79 2.14E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0764 d0b5645b6c24e0192b0f5a08f61be956 116 Pfam PF01022 Bacterial regulatory protein, arsR family 13 58 9.1E-15 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0764 d0b5645b6c24e0192b0f5a08f61be956 116 SMART SM00418 6 89 5.2E-24 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_2401 89f978a7a7a423514d38b582bad02b2a 274 SUPERFAMILY SSF53681 116 249 1.0E-21 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_2401 89f978a7a7a423514d38b582bad02b2a 274 Gene3D G3DSA:3.40.50.1860 12 248 1.1E-70 T 13-10-2018 CLOST_2401 89f978a7a7a423514d38b582bad02b2a 274 SUPERFAMILY SSF53681 11 112 1.57E-34 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_2401 89f978a7a7a423514d38b582bad02b2a 274 TIGRFAM TIGR00067 glut_race: glutamate racemase 12 249 8.2E-74 T 13-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_2401 89f978a7a7a423514d38b582bad02b2a 274 Pfam PF01177 Asp/Glu/Hydantoin racemase 12 221 2.1E-26 T 13-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_2401 89f978a7a7a423514d38b582bad02b2a 274 Gene3D G3DSA:3.40.50.1860 101 214 1.1E-70 T 13-10-2018 CLOST_2401 89f978a7a7a423514d38b582bad02b2a 274 Hamap MF_00258 Glutamate racemase [murI]. 10 261 32.191 T 13-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_2401 89f978a7a7a423514d38b582bad02b2a 274 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 76 84 - T 13-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CLOST_2547 e56d93b7911b13048761e47d39dd249f 255 Gene3D G3DSA:3.40.50.300 1 255 8.5E-67 T 13-10-2018 CLOST_2547 e56d93b7911b13048761e47d39dd249f 255 Pfam PF13614 AAA domain 3 178 7.4E-55 T 13-10-2018 IPR025669 AAA domain CLOST_2547 e56d93b7911b13048761e47d39dd249f 255 SUPERFAMILY SSF52540 2 254 4.62E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0628 d3cb058eca17d5e37836df791aab5b70 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 10 174 9.0E-60 T 13-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CLOST_0628 d3cb058eca17d5e37836df791aab5b70 180 SUPERFAMILY SSF53271 2 177 4.2E-51 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_0628 d3cb058eca17d5e37836df791aab5b70 180 Pfam PF00156 Phosphoribosyl transferase domain 15 160 1.2E-24 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOST_0628 d3cb058eca17d5e37836df791aab5b70 180 Gene3D G3DSA:3.40.50.2020 1 180 1.1E-64 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 SUPERFAMILY SSF52402 180 430 1.68E-56 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 Pfam PF00117 Glutamine amidotransferase class-I 8 187 4.3E-39 T 13-10-2018 IPR017926 Glutamine amidotransferase CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 200 509 3.2E-154 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 Pfam PF00958 GMP synthase C terminal domain 417 508 5.4E-42 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 SUPERFAMILY SSF54810 389 509 1.15E-50 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 Pfam PF02540 NAD synthase 210 254 1.1E-4 T 13-10-2018 IPR022310 NAD/GMP synthase CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 7.2E-7 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 6 20 7.2E-7 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 7.2E-7 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 190 7.8E-74 T 13-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 SUPERFAMILY SSF52317 3 224 3.48E-53 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 Gene3D G3DSA:3.30.300.10 390 509 3.2E-51 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 1.9E-5 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.9E-5 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 1.9E-5 T 13-10-2018 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 509 54.265 T 13-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 Gene3D G3DSA:3.40.50.880 1 192 6.0E-56 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0297 9bc97686fcd81b536b8eb9795dfd991b 509 Gene3D G3DSA:3.40.50.620 195 389 1.7E-74 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0220 93f9ae361c4a9b12917372d72499a2fe 252 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 7 88 2.8E-32 T 13-10-2018 IPR010627 Peptidase A24A, N-terminal CLOST_0220 93f9ae361c4a9b12917372d72499a2fe 252 Pfam PF01478 Type IV leader peptidase family 102 207 8.4E-13 T 13-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CLOST_2509 81c971fb64be63db86bf99b4c3ef6386 344 Gene3D G3DSA:1.10.3290.10 32 279 2.2E-53 T 13-10-2018 IPR036597 Fido-like domain superfamily CLOST_2509 81c971fb64be63db86bf99b4c3ef6386 344 SUPERFAMILY SSF140931 92 264 2.09E-39 T 13-10-2018 IPR036597 Fido-like domain superfamily CLOST_2509 81c971fb64be63db86bf99b4c3ef6386 344 Pfam PF02661 Fic/DOC family 113 209 5.9E-22 T 13-10-2018 IPR003812 Fido domain CLOST_1546 39c7075e07c7d04ccd2abac1138c0f21 124 Gene3D G3DSA:3.30.40.60 1 100 1.0E-14 T 13-10-2018 CLOST_1546 39c7075e07c7d04ccd2abac1138c0f21 124 SMART SM00507 8 69 1.2E-5 T 13-10-2018 IPR003615 HNH nuclease CLOST_1546 39c7075e07c7d04ccd2abac1138c0f21 124 Pfam PF01844 HNH endonuclease 21 71 5.2E-9 T 13-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CLOST_1546 39c7075e07c7d04ccd2abac1138c0f21 124 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 21 41 - T 13-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 CLOST_2023 3c2a2b5095f5826b42b69a79aef7e12f 121 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 102 7.3E-21 T 13-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis CLOST_2023 3c2a2b5095f5826b42b69a79aef7e12f 121 Gene3D G3DSA:3.30.420.130 1 119 2.5E-30 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CLOST_2023 3c2a2b5095f5826b42b69a79aef7e12f 121 SUPERFAMILY SSF53146 1 119 6.93E-29 T 13-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CLOST_0673 bb49abc3fc972ea4ec3a633932758d4b 282 SUPERFAMILY SSF53639 11 220 9.42E-56 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CLOST_0673 bb49abc3fc972ea4ec3a633932758d4b 282 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 19 191 4.7E-46 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal CLOST_0673 bb49abc3fc972ea4ec3a633932758d4b 282 Gene3D G3DSA:3.40.225.10 12 219 1.0E-65 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CLOST_0673 bb49abc3fc972ea4ec3a633932758d4b 282 SMART SM01007 17 193 8.8E-56 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal CLOST_1682 b4ba287289124afc8329bda8d0b43541 347 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 14 321 8.6E-99 T 13-10-2018 IPR017582 tRNA 2-selenouridine/geranyl-2-thiouridine synthase GO:0016785|GO:0043828|GO:0070329 CLOST_1682 b4ba287289124afc8329bda8d0b43541 347 SMART SM00450 1 130 8.3E-15 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1682 b4ba287289124afc8329bda8d0b43541 347 Gene3D G3DSA:3.40.250.10 1 131 7.5E-45 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1682 b4ba287289124afc8329bda8d0b43541 347 Pfam PF00581 Rhodanese-like domain 11 125 8.4E-10 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1682 b4ba287289124afc8329bda8d0b43541 347 SUPERFAMILY SSF52821 2 152 2.1E-25 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1682 b4ba287289124afc8329bda8d0b43541 347 SUPERFAMILY SSF52540 137 341 5.54E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1221 95a439184565b742f4db89f60e0589de 221 SUPERFAMILY SSF89550 1 194 8.37E-36 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CLOST_1221 95a439184565b742f4db89f60e0589de 221 Gene3D G3DSA:3.20.20.140 1 208 2.6E-35 T 13-10-2018 CLOST_1221 95a439184565b742f4db89f60e0589de 221 SMART SM00481 3 70 1.5E-7 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CLOST_1221 95a439184565b742f4db89f60e0589de 221 Pfam PF13263 PHP-associated 138 192 3.0E-13 T 13-10-2018 CLOST_1221 95a439184565b742f4db89f60e0589de 221 Pfam PF02811 PHP domain 4 95 6.4E-9 T 13-10-2018 IPR004013 PHP domain GO:0003824 CLOST_0246 a9d408ffd8ba6d35116e03dc24059a3d 481 Gene3D G3DSA:3.30.420.40 143 271 6.7E-6 T 13-10-2018 CLOST_0246 a9d408ffd8ba6d35116e03dc24059a3d 481 Pfam PF06277 Ethanolamine utilisation protein EutA 3 480 8.0E-184 T 13-10-2018 IPR009377 Ethanolamine utilisation EutA CLOST_0246 a9d408ffd8ba6d35116e03dc24059a3d 481 SUPERFAMILY SSF53067 7 319 7.99E-12 T 13-10-2018 CLOST_0246 a9d408ffd8ba6d35116e03dc24059a3d 481 PIRSF PIRSF012293 1 481 2.1E-174 T 13-10-2018 IPR009377 Ethanolamine utilisation EutA CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 547 565 4.5E-43 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 668 4.5E-43 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 592 610 4.5E-43 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 621 639 4.5E-43 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Gene3D G3DSA:1.10.1780.10 1 148 3.2E-40 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Gene3D G3DSA:3.40.50.300 475 724 2.7E-99 T 13-10-2018 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 211 334 1.2E-14 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 725 805 1.0E-24 T 13-10-2018 IPR019489 Clp ATPase, C-terminal CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Gene3D G3DSA:3.40.50.300 155 349 3.2E-71 T 13-10-2018 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 301 313 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Pfam PF02151 UvrB/uvrC motif 424 458 1.1E-7 T 13-10-2018 IPR001943 UVR domain GO:0005515 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 577 595 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 SMART SM01086 725 814 5.3E-31 T 13-10-2018 IPR019489 Clp ATPase, C-terminal CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 SUPERFAMILY SSF52540 492 814 9.69E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 1.7E-12 T 13-10-2018 IPR004176 Clp, N-terminal CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 65 2.3E-12 T 13-10-2018 IPR004176 Clp, N-terminal CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 SUPERFAMILY SSF52540 167 477 9.9E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 SUPERFAMILY SSF81923 3 148 2.75E-25 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Gene3D G3DSA:1.10.8.60 725 820 2.2E-26 T 13-10-2018 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Gene3D G3DSA:3.40.50.300 350 474 1.5E-42 T 13-10-2018 CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 SMART SM00382 206 350 5.3E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 SMART SM00382 543 689 2.9E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0160 2b23a16ef0ac8d45b866de381d74a514 821 Pfam PF07724 AAA domain (Cdc48 subfamily) 542 719 3.0E-57 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_2394 2c76ed9d6124aff3f7958ba8a0c2f37c 353 SUPERFAMILY SSF53686 7 349 3.4E-99 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_2394 2c76ed9d6124aff3f7958ba8a0c2f37c 353 TIGRFAM TIGR00260 thrC: threonine synthase 8 325 2.4E-94 T 13-10-2018 IPR004450 Threonine synthase-like CLOST_2394 2c76ed9d6124aff3f7958ba8a0c2f37c 353 PIRSF PIRSF038945 1 350 1.3E-155 T 13-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CLOST_2394 2c76ed9d6124aff3f7958ba8a0c2f37c 353 Gene3D G3DSA:3.40.50.1100 12 324 5.6E-123 T 13-10-2018 CLOST_2394 2c76ed9d6124aff3f7958ba8a0c2f37c 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 318 2.2E-72 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_2394 2c76ed9d6124aff3f7958ba8a0c2f37c 353 Gene3D G3DSA:3.40.50.1100 60 156 5.6E-123 T 13-10-2018 CLOST_2394 2c76ed9d6124aff3f7958ba8a0c2f37c 353 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 Gene3D G3DSA:2.40.30.110 283 365 3.3E-28 T 13-10-2018 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 365 45.592 T 13-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 PIRSF PIRSF006487 1 365 6.5E-104 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 SUPERFAMILY SSF103025 4 283 3.92E-99 T 13-10-2018 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 SUPERFAMILY SSF101790 276 364 5.4E-24 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 364 1.9E-130 T 13-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 Gene3D G3DSA:4.10.1250.10 240 281 2.1E-19 T 13-10-2018 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 Gene3D G3DSA:3.30.70.1400 54 140 1.6E-92 T 13-10-2018 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 Pfam PF01571 Aminomethyltransferase folate-binding domain 16 261 5.4E-93 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 269 358 3.5E-26 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CLOST_0426 073a13a3b9b2bbdfe524a7a30ab11cbd 365 Gene3D G3DSA:3.30.1360.120 7 239 1.6E-92 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 Gene3D G3DSA:4.10.950.10 197 276 1.8E-35 T 13-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 SUPERFAMILY SSF50104 126 272 9.03E-61 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 SMART SM01382 124 253 1.5E-93 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 PIRSF PIRSF002158 3 276 2.9E-98 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 SUPERFAMILY SSF50249 2 125 2.36E-51 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 SMART SM01383 42 118 1.6E-46 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 4.4E-34 T 13-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 5.9E-136 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 Gene3D G3DSA:2.40.50.140 1 114 5.4E-50 T 13-10-2018 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 13-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 Gene3D G3DSA:2.30.30.30 118 196 1.6E-33 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.158 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CLOST_2195 6624ea79d7aa4cc97fd6a36a5956b877 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 7.4E-56 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CLOST_1422 5dec3e5baaefadd0deccef562dd86b59 552 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 552 45.21 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CLOST_1422 5dec3e5baaefadd0deccef562dd86b59 552 SUPERFAMILY SSF52016 370 551 7.3E-55 T 13-10-2018 CLOST_1422 5dec3e5baaefadd0deccef562dd86b59 552 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 551 2.2E-229 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CLOST_1422 5dec3e5baaefadd0deccef562dd86b59 552 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CLOST_1422 5dec3e5baaefadd0deccef562dd86b59 552 Gene3D G3DSA:3.50.30.80 370 521 3.6E-50 T 13-10-2018 CLOST_1422 5dec3e5baaefadd0deccef562dd86b59 552 Pfam PF00920 Dehydratase family 31 549 2.8E-216 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CLOST_1422 5dec3e5baaefadd0deccef562dd86b59 552 SUPERFAMILY SSF143975 2 369 3.66E-135 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CLOST_1422 5dec3e5baaefadd0deccef562dd86b59 552 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 458 469 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 SUPERFAMILY SSF51735 163 307 3.03E-23 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 9 154 9.8E-41 T 13-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 PIRSF PIRSF000445 4 415 2.3E-117 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 Gene3D G3DSA:3.40.50.720 162 309 4.3E-32 T 13-10-2018 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 5 412 24.794 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 301 2.2E-27 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 316 414 1.2E-18 T 13-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 SUPERFAMILY SSF69742 5 158 7.72E-38 T 13-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 Gene3D G3DSA:3.30.460.30 4 158 3.2E-45 T 13-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 13-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 SUPERFAMILY SSF69075 315 414 2.48E-14 T 13-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_0996 36d009da62d6d590a76dd870a3e8b95a 415 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 7 414 6.6E-103 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 8 333 41.94 T 13-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 8 332 2.4E-112 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 Gene3D G3DSA:3.40.50.620 11 331 3.2E-140 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 Pfam PF00579 tRNA synthetases class I (W and Y) 9 285 5.1E-83 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 Gene3D G3DSA:1.10.240.10 191 300 3.2E-140 T 13-10-2018 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 3.8E-28 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 147 168 3.8E-28 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 71 90 3.8E-28 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 200 210 3.8E-28 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CLOST_1872 e640ed43e6c961a4598cb3d59c035791 339 SUPERFAMILY SSF52374 10 332 6.03E-99 T 13-10-2018 CLOST_1211 9d1fb87cf7deac1fd0800fd114788967 174 Gene3D G3DSA:1.10.3720.10 1 173 1.1E-35 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1211 9d1fb87cf7deac1fd0800fd114788967 174 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 18 162 2.2E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_1211 9d1fb87cf7deac1fd0800fd114788967 174 SUPERFAMILY SSF161098 1 161 5.1E-34 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2295 16bba3b8362168f532d54571854d5711 576 Gene3D G3DSA:3.40.50.11540 142 321 8.5E-79 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2295 16bba3b8362168f532d54571854d5711 576 Gene3D G3DSA:3.10.20.600 322 416 3.3E-29 T 13-10-2018 CLOST_2295 16bba3b8362168f532d54571854d5711 576 Gene3D G3DSA:1.20.1440.230 417 518 6.2E-35 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2295 16bba3b8362168f532d54571854d5711 576 Pfam PF10531 SLBB domain 333 381 3.4E-6 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2295 16bba3b8362168f532d54571854d5711 576 SUPERFAMILY SSF52833 2 74 1.79E-9 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_2295 16bba3b8362168f532d54571854d5711 576 SUPERFAMILY SSF54862 521 575 6.39E-15 T 13-10-2018 CLOST_2295 16bba3b8362168f532d54571854d5711 576 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 420 504 7.0E-32 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2295 16bba3b8362168f532d54571854d5711 576 SUPERFAMILY SSF142984 331 414 8.76E-24 T 13-10-2018 CLOST_2295 16bba3b8362168f532d54571854d5711 576 Pfam PF00037 4Fe-4S binding domain 553 574 1.8E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2295 16bba3b8362168f532d54571854d5711 576 Pfam PF00037 4Fe-4S binding domain 521 544 2.5E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2295 16bba3b8362168f532d54571854d5711 576 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 137 309 1.4E-48 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2295 16bba3b8362168f532d54571854d5711 576 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 528 539 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2295 16bba3b8362168f532d54571854d5711 576 SUPERFAMILY SSF142019 92 330 5.89E-89 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2295 16bba3b8362168f532d54571854d5711 576 SMART SM00928 419 464 1.0E-23 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2295 16bba3b8362168f532d54571854d5711 576 Gene3D G3DSA:3.40.30.10 2 90 3.0E-8 T 13-10-2018 CLOST_2295 16bba3b8362168f532d54571854d5711 576 SUPERFAMILY SSF140490 415 516 6.28E-38 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2295 16bba3b8362168f532d54571854d5711 576 Gene3D G3DSA:3.30.70.20 523 573 2.4E-13 T 13-10-2018 CLOST_1974 4054dca27cd6e275cb7b5a0fa82f0b01 165 Gene3D G3DSA:3.40.630.30 8 162 9.6E-20 T 13-10-2018 CLOST_1974 4054dca27cd6e275cb7b5a0fa82f0b01 165 Pfam PF00583 Acetyltransferase (GNAT) family 45 143 1.5E-11 T 13-10-2018 IPR000182 GNAT domain CLOST_1974 4054dca27cd6e275cb7b5a0fa82f0b01 165 SUPERFAMILY SSF55729 11 156 3.82E-21 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1974 4054dca27cd6e275cb7b5a0fa82f0b01 165 PIRSF PIRSF028520 2 165 5.3E-40 T 13-10-2018 IPR016890 Uncharacterised conserved protein UCP028520 CLOST_1376 8185c975802eef4b20592d6f25c3046c 229 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 215 1.3E-56 T 13-10-2018 IPR018768 Domain of unknown function DUF2344 CLOST_1376 8185c975802eef4b20592d6f25c3046c 229 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 190 2.7E-50 T 13-10-2018 IPR018768 Domain of unknown function DUF2344 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 543 1.5E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 519 1.5E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 562 1.5E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 481 1.5E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Gene3D G3DSA:2.30.30.40 565 691 4.5E-40 T 13-10-2018 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Gene3D G3DSA:2.40.50.180 588 651 4.5E-40 T 13-10-2018 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SMART SM00073 4 101 2.4E-28 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SUPERFAMILY SSF50341 564 696 5.23E-32 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Pfam PF01627 Hpt domain 7 97 4.0E-18 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SUPERFAMILY SSF47384 318 378 3.81E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SMART SM00387 422 565 1.3E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SUPERFAMILY SSF55874 379 563 1.03E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SMART SM00260 557 696 7.7E-34 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SUPERFAMILY SSF47226 4 126 5.36E-31 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Pfam PF07194 P2 response regulator binding domain 173 252 3.9E-27 T 13-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SUPERFAMILY SSF55052 170 252 3.4E-24 T 13-10-2018 IPR035891 CheY-binding domain of CheA CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 SMART SM01231 317 377 1.5E-16 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 318 376 2.8E-13 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Gene3D G3DSA:3.30.565.10 378 564 1.3E-59 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 564 1.7E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Gene3D G3DSA:1.10.287.560 317 377 1.5E-17 T 13-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Pfam PF01584 CheW-like domain 569 695 8.4E-23 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Gene3D G3DSA:1.20.120.160 1 145 7.8E-40 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 CLOST_1714 12876ae4cb3226bb4e9557b587a63597 696 Gene3D G3DSA:3.30.70.1110 170 253 6.8E-29 T 13-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily CLOST_1042 603157a15a92072c0027ae497a9da718 187 Pfam PF01966 HD domain 20 94 3.6E-5 T 13-10-2018 IPR006674 HD domain CLOST_1042 603157a15a92072c0027ae497a9da718 187 SUPERFAMILY SSF109604 8 130 4.19E-13 T 13-10-2018 CLOST_1042 603157a15a92072c0027ae497a9da718 187 SMART SM00471 15 127 0.0039 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_1042 603157a15a92072c0027ae497a9da718 187 Gene3D G3DSA:1.10.3210.10 1 161 7.3E-11 T 13-10-2018 CLOST_0520 4a2285e7bd7c984c639c2b9cf727fa88 207 SUPERFAMILY SSF53850 1 198 6.21E-57 T 13-10-2018 CLOST_0520 4a2285e7bd7c984c639c2b9cf727fa88 207 Gene3D G3DSA:3.40.190.10 3 188 3.6E-61 T 13-10-2018 CLOST_0520 4a2285e7bd7c984c639c2b9cf727fa88 207 Gene3D G3DSA:3.40.190.10 89 170 3.6E-61 T 13-10-2018 CLOST_0520 4a2285e7bd7c984c639c2b9cf727fa88 207 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 178 3.8E-56 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CLOST_0520 4a2285e7bd7c984c639c2b9cf727fa88 207 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 202 42.383 T 13-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CLOST_0520 4a2285e7bd7c984c639c2b9cf727fa88 207 Pfam PF01634 ATP phosphoribosyltransferase 48 198 1.4E-48 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CLOST_0520 4a2285e7bd7c984c639c2b9cf727fa88 207 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 137 158 - T 13-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 Gene3D G3DSA:3.10.310.10 3 272 1.9E-92 T 13-10-2018 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 SUPERFAMILY SSF54506 141 274 1.26E-37 T 13-10-2018 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 62 76 - T 13-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 Pfam PF01678 Diaminopimelate epimerase 3 124 7.4E-31 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 Pfam PF01678 Diaminopimelate epimerase 155 268 2.9E-20 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 276 34.456 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 274 6.4E-85 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 SUPERFAMILY SSF54506 1 131 1.31E-37 T 13-10-2018 CLOST_1863 eb95f7bcfc5cc99b3df8659a98870d2e 281 Gene3D G3DSA:3.10.310.10 121 266 1.9E-92 T 13-10-2018 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 Gene3D G3DSA:3.40.1160.10 1 311 1.2E-122 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 Pfam PF00696 Amino acid kinase family 4 292 1.9E-32 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 PIRSF PIRSF000723 1 311 2.4E-125 T 13-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 SUPERFAMILY SSF53633 4 309 9.29E-84 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 PRINTS PR01469 Bacterial carbamate kinase signature 265 280 2.1E-63 T 13-10-2018 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 PRINTS PR01469 Bacterial carbamate kinase signature 73 91 2.1E-63 T 13-10-2018 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 PRINTS PR01469 Bacterial carbamate kinase signature 210 225 2.1E-63 T 13-10-2018 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 PRINTS PR01469 Bacterial carbamate kinase signature 180 198 2.1E-63 T 13-10-2018 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 PRINTS PR01469 Bacterial carbamate kinase signature 39 58 2.1E-63 T 13-10-2018 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 PRINTS PR01469 Bacterial carbamate kinase signature 157 176 2.1E-63 T 13-10-2018 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 PRINTS PR01469 Bacterial carbamate kinase signature 108 127 2.1E-63 T 13-10-2018 CLOST_0928 ed98c065c4c034bfb8b84f36851c9ff2 311 TIGRFAM TIGR00746 arcC: carbamate kinase 4 311 6.6E-121 T 13-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CLOST_0532 9a3b237f07a67404c16f3cbcf24e778a 212 SMART SM00382 22 205 5.5E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0532 9a3b237f07a67404c16f3cbcf24e778a 212 Gene3D G3DSA:3.40.50.300 2 211 3.2E-53 T 13-10-2018 CLOST_0532 9a3b237f07a67404c16f3cbcf24e778a 212 Pfam PF00005 ABC transporter 17 155 4.7E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0532 9a3b237f07a67404c16f3cbcf24e778a 212 SUPERFAMILY SSF52540 12 207 4.02E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0532 9a3b237f07a67404c16f3cbcf24e778a 212 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1304 c508699ee7828c827b004999e837bbaf 154 Gene3D G3DSA:3.50.80.10 1 153 4.7E-56 T 13-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily CLOST_1304 c508699ee7828c827b004999e837bbaf 154 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 150 1.4E-51 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CLOST_1304 c508699ee7828c827b004999e837bbaf 154 SUPERFAMILY SSF69500 1 150 1.44E-53 T 13-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily CLOST_1304 c508699ee7828c827b004999e837bbaf 154 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 150 34.899 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CLOST_1304 c508699ee7828c827b004999e837bbaf 154 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 149 7.9E-54 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CLOST_2140 b3866cf2b45aaa27bcc3321eb824de8b 473 Gene3D G3DSA:3.30.460.10 2 133 2.7E-6 T 13-10-2018 CLOST_2140 b3866cf2b45aaa27bcc3321eb824de8b 473 TIGRFAM TIGR00277 HDIG: HDIG domain 283 328 3.4E-8 T 13-10-2018 IPR006675 HDIG domain CLOST_2140 b3866cf2b45aaa27bcc3321eb824de8b 473 Gene3D G3DSA:1.10.3090.10 134 449 1.3E-19 T 13-10-2018 CLOST_2140 b3866cf2b45aaa27bcc3321eb824de8b 473 Pfam PF01966 HD domain 240 387 5.2E-10 T 13-10-2018 IPR006674 HD domain CLOST_2140 b3866cf2b45aaa27bcc3321eb824de8b 473 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 164 225 1.3E-5 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CLOST_2140 b3866cf2b45aaa27bcc3321eb824de8b 473 SUPERFAMILY SSF81891 136 469 1.69E-17 T 13-10-2018 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 416 425 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 227 240 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 SUPERFAMILY SSF52540 202 445 6.94E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 Gene3D G3DSA:1.10.8.60 375 440 8.1E-23 T 13-10-2018 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 Pfam PF13426 PAS domain 35 165 3.6E-11 T 13-10-2018 IPR000014 PAS domain CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 Gene3D G3DSA:3.40.50.300 193 374 5.6E-67 T 13-10-2018 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 SMART SM00091 24 94 9.9E-4 T 13-10-2018 IPR000014 PAS domain CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 Pfam PF02954 Bacterial regulatory protein, Fis family 469 506 4.7E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 Gene3D G3DSA:1.10.10.60 460 512 6.0E-10 T 13-10-2018 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 290 305 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 SUPERFAMILY SSF55785 20 76 1.92E-11 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 Gene3D G3DSA:3.30.450.20 13 192 2.1E-16 T 13-10-2018 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 SUPERFAMILY SSF46689 458 510 9.86E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 Pfam PF00158 Sigma-54 interaction domain 203 371 1.3E-70 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 28 90 2.9E-9 T 13-10-2018 IPR000014 PAS domain CLOST_0200 fc48d85cea8dda50a9c60b6f643bcd70 513 SMART SM00382 223 371 3.4E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1622 1ab73cc48df5ee6db6d77c3cbf345d51 148 Gene3D G3DSA:3.40.1550.10 1 147 7.3E-38 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_1622 1ab73cc48df5ee6db6d77c3cbf345d51 148 Pfam PF13690 Chemotaxis phosphatase CheX 39 134 1.3E-14 T 13-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain CLOST_1622 1ab73cc48df5ee6db6d77c3cbf345d51 148 SUPERFAMILY SSF103039 2 146 4.32E-30 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 PRINTS PR01466 Bacterial arginine deiminase signature 5 25 1.2E-60 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 PRINTS PR01466 Bacterial arginine deiminase signature 155 173 1.2E-60 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 PRINTS PR01466 Bacterial arginine deiminase signature 183 198 1.2E-60 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 PRINTS PR01466 Bacterial arginine deiminase signature 366 380 1.2E-60 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 PRINTS PR01466 Bacterial arginine deiminase signature 389 407 1.2E-60 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 PRINTS PR01466 Bacterial arginine deiminase signature 346 363 1.2E-60 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 Pfam PF02274 Amidinotransferase 21 407 6.6E-110 T 13-10-2018 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 SUPERFAMILY SSF55909 7 410 3.73E-134 T 13-10-2018 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 TIGRFAM TIGR01078 arcA: arginine deiminase 7 409 1.0E-173 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 Gene3D G3DSA:1.10.3930.10 71 155 1.1E-166 T 13-10-2018 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 Hamap MF_00242 Arginine deiminase [arcA]. 4 410 46.748 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 PIRSF PIRSF006356 1 410 2.3E-174 T 13-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CLOST_0926 34babb53506e69f043d4cb9ef152a764 410 Gene3D G3DSA:3.75.10.10 8 405 1.1E-166 T 13-10-2018 CLOST_2495 0f1db0b72ac282c76608aea5afd1bdfa 238 SMART SM00382 26 214 6.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2495 0f1db0b72ac282c76608aea5afd1bdfa 238 Gene3D G3DSA:3.40.50.300 1 220 1.7E-64 T 13-10-2018 CLOST_2495 0f1db0b72ac282c76608aea5afd1bdfa 238 Pfam PF00005 ABC transporter 17 166 2.2E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2495 0f1db0b72ac282c76608aea5afd1bdfa 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2495 0f1db0b72ac282c76608aea5afd1bdfa 238 SUPERFAMILY SSF52540 1 217 1.27E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1290 2def9d4c794094d63600c0e03600f32c 740 Gene3D G3DSA:3.40.50.280 588 737 1.5E-42 T 13-10-2018 CLOST_1290 2def9d4c794094d63600c0e03600f32c 740 Pfam PF09043 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 66 446 1.1E-44 T 13-10-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CLOST_1290 2def9d4c794094d63600c0e03600f32c 740 Gene3D G3DSA:3.30.30.60 506 578 2.1E-36 T 13-10-2018 IPR036843 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain superfamily GO:0046983 CLOST_1290 2def9d4c794094d63600c0e03600f32c 740 Pfam PF16554 Dimerisation domain of d-ornithine 4,5-aminomutase 507 583 9.5E-29 T 13-10-2018 IPR028991 D-lysine 5,6-aminomutase beta subunit KamE, N-terminal GO:0046983 CLOST_1290 2def9d4c794094d63600c0e03600f32c 740 SUPERFAMILY SSF52242 600 734 2.62E-32 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_1290 2def9d4c794094d63600c0e03600f32c 740 Pfam PF02310 B12 binding domain 604 722 1.6E-14 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_1290 2def9d4c794094d63600c0e03600f32c 740 SUPERFAMILY SSF51703 7 452 1.18E-169 T 13-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CLOST_1290 2def9d4c794094d63600c0e03600f32c 740 Gene3D G3DSA:3.20.20.440 19 431 9.0E-214 T 13-10-2018 IPR037086 D-Lysine 5,6-aminomutase alpha subunit superfamily CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 Gene3D G3DSA:3.30.565.10 6 216 1.9E-62 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 Gene3D G3DSA:3.30.230.10 220 330 2.6E-28 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 SUPERFAMILY SSF55874 5 217 3.57E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 123 4.7E-11 T 13-10-2018 CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 SUPERFAMILY SSF118116 447 632 4.58E-45 T 13-10-2018 IPR037198 MutL, C-terminal domain superfamily CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 SMART SM01340 212 331 2.6E-35 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 5 630 23.784 T 13-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 97 103 - T 13-10-2018 IPR014762 DNA mismatch repair, conserved site CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 Pfam PF08676 MutL C terminal dimerisation domain 449 590 7.5E-36 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 6 310 1.5E-91 T 13-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 215 330 3.4E-29 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 SUPERFAMILY SSF54211 194 331 7.21E-28 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 Gene3D G3DSA:3.30.1370.100 492 587 4.0E-56 T 13-10-2018 CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 SMART SM00853 450 590 9.5E-37 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CLOST_1229 feb3ea970cefc3c9111fee3c2a513301 634 Gene3D G3DSA:2.30.42.20 451 632 4.0E-56 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 1.6E-58 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.7E-8 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.7E-8 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 Pfam PF00117 Glutamine amidotransferase class-I 3 186 9.6E-44 T 13-10-2018 IPR017926 Glutamine amidotransferase CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 3.4E-14 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 3.4E-14 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 3.4E-14 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 Gene3D G3DSA:3.40.50.880 1 188 6.5E-58 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 SUPERFAMILY SSF52317 1 188 2.89E-48 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00097 Anthranilate synthase component II signature 165 178 2.1E-32 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.1E-32 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00097 Anthranilate synthase component II signature 120 132 2.1E-32 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.1E-32 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.1E-32 T 13-10-2018 CLOST_1994 de7d5d70e4fd1583e191cee220530ee8 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.1E-32 T 13-10-2018 CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 Pfam PF00990 Diguanylate cyclase, GGDEF domain 408 496 4.4E-14 T 13-10-2018 IPR000160 GGDEF domain CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 SUPERFAMILY SSF141868 4 238 1.31E-64 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 Gene3D G3DSA:3.20.20.450 2 242 1.7E-63 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 Pfam PF00563 EAL domain 9 236 4.5E-53 T 13-10-2018 IPR001633 EAL domain CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 SUPERFAMILY SSF55073 409 572 7.45E-21 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 SMART SM00267 393 533 8.3E-7 T 13-10-2018 IPR000160 GGDEF domain CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 SUPERFAMILY SSF54631 291 393 2.8E-10 T 13-10-2018 CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 404 497 7.8E-14 T 13-10-2018 IPR000160 GGDEF domain CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 Gene3D G3DSA:3.30.70.270 404 577 2.8E-21 T 13-10-2018 CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 Pfam PF00571 CBS domain 338 394 0.0012 T 13-10-2018 IPR000644 CBS domain CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 Pfam PF00571 CBS domain 293 324 4.9E-4 T 13-10-2018 IPR000644 CBS domain CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 SMART SM00052 1 241 2.3E-37 T 13-10-2018 IPR001633 EAL domain CLOST_2561 1e2e0f220df474f1261a771fe37c795e 578 Gene3D G3DSA:3.10.580.10 273 403 7.0E-11 T 13-10-2018 CLOST_0290 310321797abf739826fd5b33d13ede00 597 SUPERFAMILY SSF90123 15 342 1.57E-86 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0290 310321797abf739826fd5b33d13ede00 597 SUPERFAMILY SSF52540 348 594 2.25E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0290 310321797abf739826fd5b33d13ede00 597 Pfam PF00664 ABC transporter transmembrane region 33 310 3.2E-57 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 CLOST_0290 310321797abf739826fd5b33d13ede00 597 Gene3D G3DSA:1.20.1560.10 5 342 1.2E-96 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0290 310321797abf739826fd5b33d13ede00 597 Pfam PF00005 ABC transporter 375 524 6.0E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0290 310321797abf739826fd5b33d13ede00 597 Gene3D G3DSA:3.40.50.300 343 596 1.7E-85 T 13-10-2018 CLOST_0290 310321797abf739826fd5b33d13ede00 597 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0290 310321797abf739826fd5b33d13ede00 597 SMART SM00382 384 570 2.6E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2260 5fbff229d64b4f4fe22fca24793b1e7e 336 SUPERFAMILY SSF56601 7 316 6.42E-72 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like CLOST_2260 5fbff229d64b4f4fe22fca24793b1e7e 336 Gene3D G3DSA:3.40.710.10 3 329 2.0E-99 T 13-10-2018 CLOST_2260 5fbff229d64b4f4fe22fca24793b1e7e 336 Pfam PF00144 Beta-lactamase 12 327 1.0E-49 T 13-10-2018 IPR001466 Beta-lactamase-related CLOST_1075 45b4ea83828d77f5a30723a2fc0baa53 546 Pfam PF02554 Carbon starvation protein CstA 1 356 4.4E-128 T 13-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CLOST_1075 45b4ea83828d77f5a30723a2fc0baa53 546 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 381 495 1.4E-37 T 13-10-2018 IPR025299 CstA, C-terminal domain CLOST_0197 78454c7f9c399b6b10a278606306de59 312 Gene3D G3DSA:3.50.30.50 208 297 8.2E-10 T 13-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CLOST_0197 78454c7f9c399b6b10a278606306de59 312 SUPERFAMILY SSF102198 6 294 1.31E-42 T 13-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CLOST_0197 78454c7f9c399b6b10a278606306de59 312 Gene3D G3DSA:3.50.30.50 1 200 1.7E-27 T 13-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CLOST_0197 78454c7f9c399b6b10a278606306de59 312 Pfam PF04199 Putative cyclase 7 170 4.4E-28 T 13-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CLOST_0805 4ee2a2143618d9ebf20c82daec97abf8 290 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 6 285 5.8E-82 T 13-10-2018 IPR003797 DegV CLOST_0805 4ee2a2143618d9ebf20c82daec97abf8 290 Gene3D G3DSA:3.30.1180.10 160 289 3.0E-45 T 13-10-2018 CLOST_0805 4ee2a2143618d9ebf20c82daec97abf8 290 Gene3D G3DSA:3.40.50.10170 2 156 2.1E-41 T 13-10-2018 CLOST_0805 4ee2a2143618d9ebf20c82daec97abf8 290 SUPERFAMILY SSF82549 4 288 1.99E-81 T 13-10-2018 CLOST_0805 4ee2a2143618d9ebf20c82daec97abf8 290 Pfam PF02645 Uncharacterised protein, DegV family COG1307 6 286 1.2E-76 T 13-10-2018 IPR003797 DegV CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 Gene3D G3DSA:3.10.290.10 325 406 3.0E-19 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 SUPERFAMILY SSF55174 328 406 2.09E-14 T 13-10-2018 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 407 42.057 T 13-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 Pfam PF01479 S4 domain 346 386 1.3E-7 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 SUPERFAMILY SSF52374 3 319 9.85E-97 T 13-10-2018 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 Gene3D G3DSA:1.10.240.10 221 324 2.0E-33 T 13-10-2018 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 406 5.1E-125 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 2.1E-24 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 2.1E-24 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 2.1E-24 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 214 226 2.1E-24 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 Pfam PF00579 tRNA synthetases class I (W and Y) 30 319 1.8E-78 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0262 17af2e31ea3fb75f45cf3e704adbf81b 408 Gene3D G3DSA:3.40.50.620 1 220 9.4E-83 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_2113 b5179155f9b722efa96dff8487608861 122 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 121 9.6E-27 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 CLOST_2113 b5179155f9b722efa96dff8487608861 122 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 122 21.241 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 CLOST_2113 b5179155f9b722efa96dff8487608861 122 SUPERFAMILY SSF56214 1 121 2.75E-29 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 CLOST_2113 b5179155f9b722efa96dff8487608861 122 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 118 4.7E-20 T 13-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 CLOST_2113 b5179155f9b722efa96dff8487608861 122 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 122 5.5E-29 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 CLOST_2113 b5179155f9b722efa96dff8487608861 122 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 87 3.0E-20 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 CLOST_2113 b5179155f9b722efa96dff8487608861 122 Gene3D G3DSA:3.90.470.20 1 121 1.1E-36 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 CLOST_0717 bf88b2d53133e2bb9df2fd7f2c012b21 128 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 126 1.8E-30 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type CLOST_0717 bf88b2d53133e2bb9df2fd7f2c012b21 128 Gene3D G3DSA:1.10.10.10 1 128 5.5E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0717 bf88b2d53133e2bb9df2fd7f2c012b21 128 SUPERFAMILY SSF46785 2 126 8.51E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0717 bf88b2d53133e2bb9df2fd7f2c012b21 128 Pfam PF02082 Transcriptional regulator 1 83 4.6E-26 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type CLOST_1904 052a5353271bf74a2c3ed772e92fb469 430 Gene3D G3DSA:3.30.830.10 239 426 6.4E-40 T 13-10-2018 CLOST_1904 052a5353271bf74a2c3ed772e92fb469 430 SUPERFAMILY SSF63411 247 427 2.83E-18 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CLOST_1904 052a5353271bf74a2c3ed772e92fb469 430 Gene3D G3DSA:3.30.830.10 9 226 1.4E-52 T 13-10-2018 CLOST_1904 052a5353271bf74a2c3ed772e92fb469 430 Pfam PF00675 Insulinase (Peptidase family M16) 62 175 1.5E-15 T 13-10-2018 IPR011765 Peptidase M16, N-terminal CLOST_1904 052a5353271bf74a2c3ed772e92fb469 430 Pfam PF05193 Peptidase M16 inactive domain 182 361 2.7E-16 T 13-10-2018 IPR007863 Peptidase M16, C-terminal CLOST_1904 052a5353271bf74a2c3ed772e92fb469 430 SUPERFAMILY SSF63411 14 221 5.76E-39 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CLOST_0372 1b6fa1816b1dc008cb9c0860465b5c6c 780 SUPERFAMILY SSF63825 578 774 2.22E-16 T 13-10-2018 CLOST_0372 1b6fa1816b1dc008cb9c0860465b5c6c 780 SUPERFAMILY SSF75011 211 605 1.96E-20 T 13-10-2018 CLOST_0372 1b6fa1816b1dc008cb9c0860465b5c6c 780 Gene3D G3DSA:2.120.10.30 181 306 3.2E-12 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like CLOST_0372 1b6fa1816b1dc008cb9c0860465b5c6c 780 Gene3D G3DSA:2.120.10.30 328 606 5.0E-29 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like CLOST_0372 1b6fa1816b1dc008cb9c0860465b5c6c 780 Gene3D G3DSA:2.120.10.30 669 772 8.4E-13 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 Gene3D G3DSA:3.50.50.60 2 339 4.3E-164 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 291 4.2E-60 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 SUPERFAMILY SSF51905 2 195 1.3E-43 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 5.7E-19 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 5.7E-19 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 386 401 5.7E-19 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 5.7E-19 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 5.7E-19 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 328 431 3.0E-17 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 SUPERFAMILY SSF55424 323 441 1.24E-33 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 Gene3D G3DSA:3.50.50.60 113 439 4.3E-164 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.8E-26 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.8E-26 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.8E-26 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 1.8E-26 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.8E-26 T 13-10-2018 CLOST_0682 9debe07e77231115c3c5e1689223d01f 443 SUPERFAMILY SSF51905 150 318 3.74E-31 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_2278 4af9481cf54f6b390e607dedc8573de5 212 Pfam PF00005 ABC transporter 17 149 9.1E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2278 4af9481cf54f6b390e607dedc8573de5 212 SMART SM00382 26 198 5.3E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2278 4af9481cf54f6b390e607dedc8573de5 212 Gene3D G3DSA:3.40.50.300 1 211 5.2E-51 T 13-10-2018 CLOST_2278 4af9481cf54f6b390e607dedc8573de5 212 SUPERFAMILY SSF52540 1 206 4.6E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2278 4af9481cf54f6b390e607dedc8573de5 212 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0947 5dbe902814a75c73c8ea96239fd351c4 319 Gene3D G3DSA:3.60.70.12 2 301 7.7E-110 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CLOST_0947 5dbe902814a75c73c8ea96239fd351c4 319 Pfam PF03576 Peptidase family S58 6 308 1.1E-53 T 13-10-2018 IPR005321 Peptidase S58, DmpA CLOST_0947 5dbe902814a75c73c8ea96239fd351c4 319 SUPERFAMILY SSF56266 6 315 7.32E-68 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CLOST_0041 dc152e3f018a12865d1cbdccf8963f8b 283 Pfam PF00491 Arginase family 19 277 3.8E-74 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 CLOST_0041 dc152e3f018a12865d1cbdccf8963f8b 283 Gene3D G3DSA:3.40.800.10 12 283 9.8E-92 T 13-10-2018 CLOST_0041 dc152e3f018a12865d1cbdccf8963f8b 283 SUPERFAMILY SSF52768 2 279 2.88E-79 T 13-10-2018 IPR023696 Ureohydrolase domain superfamily CLOST_0041 dc152e3f018a12865d1cbdccf8963f8b 283 PIRSF PIRSF036979 1 283 1.6E-89 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 CLOST_0041 dc152e3f018a12865d1cbdccf8963f8b 283 ProSitePatterns PS01053 Arginase family signature. 208 229 - T 13-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CLOST_0041 dc152e3f018a12865d1cbdccf8963f8b 283 TIGRFAM TIGR01230 agmatinase: agmatinase 8 279 1.5E-83 T 13-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CLOST_1858 6716bc2b1000f967ddf1b874ca6ba798 398 Gene3D G3DSA:3.40.50.1950 1 183 1.4E-60 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 CLOST_1858 6716bc2b1000f967ddf1b874ca6ba798 398 SUPERFAMILY SSF102645 182 395 1.27E-73 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CLOST_1858 6716bc2b1000f967ddf1b874ca6ba798 398 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 392 1.5E-146 T 13-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CLOST_1858 6716bc2b1000f967ddf1b874ca6ba798 398 Pfam PF02441 Flavoprotein 3 173 1.1E-47 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CLOST_1858 6716bc2b1000f967ddf1b874ca6ba798 398 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 183 365 4.7E-72 T 13-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CLOST_1858 6716bc2b1000f967ddf1b874ca6ba798 398 Gene3D G3DSA:3.40.50.10300 184 398 2.7E-81 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CLOST_1858 6716bc2b1000f967ddf1b874ca6ba798 398 SUPERFAMILY SSF52507 3 174 2.09E-62 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 CLOST_0268 e9e893609ca7fc73438b53b75631be28 258 PIRSF PIRSF033579 1 258 1.3E-92 T 13-10-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CLOST_0268 e9e893609ca7fc73438b53b75631be28 258 Gene3D G3DSA:3.40.50.1400 3 256 8.7E-94 T 13-10-2018 CLOST_0268 e9e893609ca7fc73438b53b75631be28 258 SUPERFAMILY SSF53800 2 256 1.83E-75 T 13-10-2018 CLOST_0268 e9e893609ca7fc73438b53b75631be28 258 Gene3D G3DSA:3.40.50.1400 114 238 8.7E-94 T 13-10-2018 CLOST_0268 e9e893609ca7fc73438b53b75631be28 258 Pfam PF06180 Cobalt chelatase (CbiK) 3 257 4.0E-88 T 13-10-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CLOST_0069 d55ea93762ccbecb1388b259f83e74be 74 Pfam PF07878 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 9 46 4.3E-6 T 13-10-2018 IPR012869 CopG-like ribbon-helix-helix domain CLOST_0069 d55ea93762ccbecb1388b259f83e74be 74 Gene3D G3DSA:1.10.1220.10 6 72 2.5E-7 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CLOST_0069 d55ea93762ccbecb1388b259f83e74be 74 SUPERFAMILY SSF47598 8 48 4.77E-8 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 CLOST_0615 a68cea33172b7b33ceacaede98ef9868 218 SUPERFAMILY SSF109755 5 217 4.5E-61 T 13-10-2018 CLOST_0615 a68cea33172b7b33ceacaede98ef9868 218 PIRSF PIRSF003107 1 218 1.9E-62 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CLOST_0615 a68cea33172b7b33ceacaede98ef9868 218 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 214 6.0E-63 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CLOST_0615 a68cea33172b7b33ceacaede98ef9868 218 Gene3D G3DSA:1.20.58.220 112 218 1.8E-32 T 13-10-2018 IPR038078 PhoU-like domain superfamily CLOST_0615 a68cea33172b7b33ceacaede98ef9868 218 Pfam PF01895 PhoU domain 20 105 6.1E-23 T 13-10-2018 IPR026022 PhoU domain CLOST_0615 a68cea33172b7b33ceacaede98ef9868 218 Pfam PF01895 PhoU domain 122 205 4.2E-17 T 13-10-2018 IPR026022 PhoU domain CLOST_0615 a68cea33172b7b33ceacaede98ef9868 218 Gene3D G3DSA:1.20.58.220 3 111 1.6E-34 T 13-10-2018 IPR038078 PhoU-like domain superfamily CLOST_0720 dc8fe11e4d22aee40310b141cd252011 420 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 319 2.6E-12 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CLOST_0720 dc8fe11e4d22aee40310b141cd252011 420 Gene3D G3DSA:2.40.30.170 54 340 4.5E-43 T 13-10-2018 CLOST_0720 dc8fe11e4d22aee40310b141cd252011 420 Gene3D G3DSA:2.40.420.20 49 398 4.5E-43 T 13-10-2018 CLOST_0720 dc8fe11e4d22aee40310b141cd252011 420 Gene3D G3DSA:1.10.287.470 99 228 4.5E-43 T 13-10-2018 CLOST_0720 dc8fe11e4d22aee40310b141cd252011 420 Gene3D G3DSA:2.40.50.100 65 262 4.5E-43 T 13-10-2018 CLOST_0720 dc8fe11e4d22aee40310b141cd252011 420 SUPERFAMILY SSF111369 55 281 1.96E-9 T 13-10-2018 CLOST_0720 dc8fe11e4d22aee40310b141cd252011 420 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 195 412 1.2E-34 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CLOST_0968 af87ea80839174206aad9ab25610f243 373 SUPERFAMILY SSF51161 287 357 8.41E-13 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_0968 af87ea80839174206aad9ab25610f243 373 SUPERFAMILY SSF53448 23 319 5.63E-48 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0968 af87ea80839174206aad9ab25610f243 373 Pfam PF00483 Nucleotidyl transferase 29 158 1.1E-10 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CLOST_0968 af87ea80839174206aad9ab25610f243 373 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 4 371 4.9E-125 T 13-10-2018 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 CLOST_0968 af87ea80839174206aad9ab25610f243 373 Gene3D G3DSA:2.160.10.10 274 373 2.2E-24 T 13-10-2018 CLOST_0968 af87ea80839174206aad9ab25610f243 373 Gene3D G3DSA:3.90.550.10 2 273 1.6E-47 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_1576 e2ea3a5a14a54cbe00d068b516976bd7 251 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 227 7.9E-64 T 13-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CLOST_1576 e2ea3a5a14a54cbe00d068b516976bd7 251 PIRSF PIRSF000386 1 251 2.0E-99 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CLOST_1576 e2ea3a5a14a54cbe00d068b516976bd7 251 Gene3D G3DSA:1.10.1270.20 181 250 2.2E-28 T 13-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CLOST_1576 e2ea3a5a14a54cbe00d068b516976bd7 251 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 240 1.4E-94 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CLOST_1576 e2ea3a5a14a54cbe00d068b516976bd7 251 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 251 100.171 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CLOST_1576 e2ea3a5a14a54cbe00d068b516976bd7 251 Gene3D G3DSA:3.40.1280.10 1 180 8.1E-74 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CLOST_1576 e2ea3a5a14a54cbe00d068b516976bd7 251 SUPERFAMILY SSF75217 1 246 5.23E-94 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases CLOST_2585 fdd292064e753098851154b77060ee41 459 Gene3D G3DSA:3.40.50.300 222 387 6.8E-110 T 13-10-2018 CLOST_2585 fdd292064e753098851154b77060ee41 459 PRINTS PR00449 Transforming protein P21 ras signature 262 284 4.3E-7 T 13-10-2018 CLOST_2585 fdd292064e753098851154b77060ee41 459 PRINTS PR00449 Transforming protein P21 ras signature 222 243 4.3E-7 T 13-10-2018 CLOST_2585 fdd292064e753098851154b77060ee41 459 PRINTS PR00449 Transforming protein P21 ras signature 390 412 4.3E-7 T 13-10-2018 CLOST_2585 fdd292064e753098851154b77060ee41 459 PRINTS PR00449 Transforming protein P21 ras signature 326 339 4.3E-7 T 13-10-2018 CLOST_2585 fdd292064e753098851154b77060ee41 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 125 7.2E-40 T 13-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CLOST_2585 fdd292064e753098851154b77060ee41 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 459 34.397 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CLOST_2585 fdd292064e753098851154b77060ee41 459 Pfam PF01926 50S ribosome-binding GTPase 224 336 2.7E-25 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_2585 fdd292064e753098851154b77060ee41 459 Gene3D G3DSA:1.20.120.430 126 459 6.8E-110 T 13-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 CLOST_2585 fdd292064e753098851154b77060ee41 459 Pfam PF12631 MnmE helical domain 128 456 3.1E-57 T 13-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CLOST_2585 fdd292064e753098851154b77060ee41 459 SUPERFAMILY SSF52540 77 375 3.45E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2585 fdd292064e753098851154b77060ee41 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 459 1.8E-125 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CLOST_2585 fdd292064e753098851154b77060ee41 459 Gene3D G3DSA:3.30.1360.120 1 125 1.6E-49 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CLOST_2585 fdd292064e753098851154b77060ee41 459 SUPERFAMILY SSF116878 126 459 1.44E-47 T 13-10-2018 CLOST_2585 fdd292064e753098851154b77060ee41 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 376 3.4E-27 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_2321 f09f47a0a6c6e0236d31b3e38d5763d6 346 Gene3D G3DSA:1.10.132.50 16 335 8.9E-28 T 13-10-2018 CLOST_2321 f09f47a0a6c6e0236d31b3e38d5763d6 346 Gene3D G3DSA:1.20.1690.10 87 190 8.9E-28 T 13-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2321 f09f47a0a6c6e0236d31b3e38d5763d6 346 Pfam PF01992 ATP synthase (C/AC39) subunit 11 338 4.5E-65 T 13-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2321 f09f47a0a6c6e0236d31b3e38d5763d6 346 SUPERFAMILY SSF103486 7 342 6.93E-42 T 13-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2321 f09f47a0a6c6e0236d31b3e38d5763d6 346 Gene3D G3DSA:1.20.1690.10 201 302 8.9E-28 T 13-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_1617 e111f0da2a9931d5c685e04bcdd3d1d7 244 Pfam PF13566 Domain of unknown function (DUF4130 80 241 2.4E-40 T 13-10-2018 IPR025404 Domain of unknown function DUF4130 CLOST_1617 e111f0da2a9931d5c685e04bcdd3d1d7 244 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 4 241 9.5E-58 T 13-10-2018 IPR023875 DNA metabolism protein, putative CLOST_2499 da72952a2d59824f4bf49bb90f7137c0 179 Gene3D G3DSA:3.40.630.30 5 167 1.9E-18 T 13-10-2018 CLOST_2499 da72952a2d59824f4bf49bb90f7137c0 179 SUPERFAMILY SSF55729 48 169 5.23E-20 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2499 da72952a2d59824f4bf49bb90f7137c0 179 Pfam PF13673 Acetyltransferase (GNAT) domain 60 158 2.4E-13 T 13-10-2018 IPR000182 GNAT domain CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 Gene3D G3DSA:3.40.1380.10 63 202 2.2E-97 T 13-10-2018 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 Hamap MF_00815 ATP synthase gamma chain [atpG]. 3 283 33.16 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 269 282 - T 13-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 Gene3D G3DSA:1.10.287.80 8 279 2.2E-97 T 13-10-2018 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 6 283 8.8E-93 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 SUPERFAMILY SSF52943 5 283 2.09E-85 T 13-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 PRINTS PR00126 ATP synthase gamma subunit signature 230 249 4.3E-37 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 4.3E-37 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 PRINTS PR00126 ATP synthase gamma subunit signature 261 282 4.3E-37 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 PRINTS PR00126 ATP synthase gamma subunit signature 163 180 4.3E-37 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2117 f3d9cc7593f036cb28900beceebf62d3 284 Pfam PF00231 ATP synthase 6 283 4.0E-94 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2433 7e2531984b2cbb8d37a0988069b21a1a 406 TIGRFAM TIGR03528 2_3_DAP_am_ly: diaminopropionate ammonia-lyase 16 396 6.2E-172 T 13-10-2018 IPR019871 Diaminopropionate ammonia-lyase, subgroup GO:0008838 CLOST_2433 7e2531984b2cbb8d37a0988069b21a1a 406 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 41 368 1.4E-54 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_2433 7e2531984b2cbb8d37a0988069b21a1a 406 Gene3D G3DSA:3.40.50.1100 76 198 5.2E-142 T 13-10-2018 CLOST_2433 7e2531984b2cbb8d37a0988069b21a1a 406 Gene3D G3DSA:3.40.50.1100 33 395 5.2E-142 T 13-10-2018 CLOST_2433 7e2531984b2cbb8d37a0988069b21a1a 406 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 24 396 3.4E-158 T 13-10-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 CLOST_2433 7e2531984b2cbb8d37a0988069b21a1a 406 SUPERFAMILY SSF53686 35 360 7.07E-59 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_1171 a270d72e0b2fe66bdb8dd639b13b9b46 708 Gene3D G3DSA:3.40.50.2030 103 288 4.3E-61 T 13-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_1171 a270d72e0b2fe66bdb8dd639b13b9b46 708 Gene3D G3DSA:3.40.1470.10 579 708 1.7E-49 T 13-10-2018 CLOST_1171 a270d72e0b2fe66bdb8dd639b13b9b46 708 Gene3D G3DSA:1.10.8.190 1 102 1.8E-28 T 13-10-2018 CLOST_1171 a270d72e0b2fe66bdb8dd639b13b9b46 708 SUPERFAMILY SSF56821 4 707 2.98E-233 T 13-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 CLOST_1171 a270d72e0b2fe66bdb8dd639b13b9b46 708 Gene3D G3DSA:3.30.1650.10 295 473 7.1E-74 T 13-10-2018 IPR038571 Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase, domain 3 superfamily KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 CLOST_1171 a270d72e0b2fe66bdb8dd639b13b9b46 708 TIGRFAM TIGR00316 cdhC: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit 296 702 3.6E-137 T 13-10-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 CLOST_1171 a270d72e0b2fe66bdb8dd639b13b9b46 708 Gene3D G3DSA:3.40.970.20 474 563 5.4E-38 T 13-10-2018 CLOST_1171 a270d72e0b2fe66bdb8dd639b13b9b46 708 Pfam PF03598 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 297 452 1.2E-72 T 13-10-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 CLOST_1237 99571a6f518e6dbccb7ca89d2afc0bdc 371 Pfam PF00589 Phage integrase family 196 353 9.3E-26 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CLOST_1237 99571a6f518e6dbccb7ca89d2afc0bdc 371 Gene3D G3DSA:1.10.150.130 26 163 9.6E-10 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal CLOST_1237 99571a6f518e6dbccb7ca89d2afc0bdc 371 SUPERFAMILY SSF56349 190 360 7.06E-30 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CLOST_1237 99571a6f518e6dbccb7ca89d2afc0bdc 371 Gene3D G3DSA:1.10.443.10 184 359 1.8E-34 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CLOST_0102 a99c59b26913491fe73952b8d0a48a42 271 SUPERFAMILY SSF55383 62 144 2.03E-23 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0102 a99c59b26913491fe73952b8d0a48a42 271 Pfam PF07833 Copper amine oxidase N-terminal domain 60 151 1.7E-25 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0102 a99c59b26913491fe73952b8d0a48a42 271 Pfam PF07833 Copper amine oxidase N-terminal domain 40 89 2.1E-10 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0102 a99c59b26913491fe73952b8d0a48a42 271 Gene3D G3DSA:3.30.457.10 64 141 1.3E-19 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0871 0208bec99e4b3ce8c89ee3e5d8979b1f 266 SUPERFAMILY SSF54001 96 243 2.26E-30 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_0871 0208bec99e4b3ce8c89ee3e5d8979b1f 266 Pfam PF01841 Transglutaminase-like superfamily 136 237 1.2E-21 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0871 0208bec99e4b3ce8c89ee3e5d8979b1f 266 SMART SM00460 182 240 7.2E-15 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0871 0208bec99e4b3ce8c89ee3e5d8979b1f 266 Gene3D G3DSA:3.10.620.30 83 264 7.8E-34 T 13-10-2018 CLOST_2420 4788425e8e057df2ce0e37c5973e8e03 140 TIGRFAM TIGR01753 flav_short: flavodoxin 4 139 7.3E-45 T 13-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 CLOST_2420 4788425e8e057df2ce0e37c5973e8e03 140 Pfam PF00258 Flavodoxin 6 132 7.8E-15 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CLOST_2420 4788425e8e057df2ce0e37c5973e8e03 140 Gene3D G3DSA:3.40.50.360 4 140 3.3E-36 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_2420 4788425e8e057df2ce0e37c5973e8e03 140 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 13-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CLOST_2420 4788425e8e057df2ce0e37c5973e8e03 140 SUPERFAMILY SSF52218 3 139 5.77E-35 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 13-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 78 3.4E-32 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 Gene3D G3DSA:4.10.640.10 2 78 2.2E-29 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 3.8E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 3.8E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 3.8E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 3.8E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 SUPERFAMILY SSF46911 4 78 1.83E-28 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 26 78 3.0E-19 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 Pfam PF01084 Ribosomal protein S18 22 73 3.1E-26 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2569 c2ada18c0694e422f090d769c60f99e8 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 5 78 21.686 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_0912 8fd5fbaef4cae9baa7cc89699f6d1e4d 223 Pfam PF00849 RNA pseudouridylate synthase 11 166 2.1E-29 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_0912 8fd5fbaef4cae9baa7cc89699f6d1e4d 223 SUPERFAMILY SSF55120 4 215 4.16E-49 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_0912 8fd5fbaef4cae9baa7cc89699f6d1e4d 223 Gene3D G3DSA:3.30.2350.10 1 212 6.0E-56 T 13-10-2018 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 SUPERFAMILY SSF55816 318 509 2.35E-61 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 Gene3D G3DSA:3.60.21.10 29 317 8.8E-88 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 SUPERFAMILY SSF56300 30 319 1.79E-79 T 13-10-2018 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 PRINTS PR01607 Apyrase family signature 33 51 2.6E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 PRINTS PR01607 Apyrase family signature 448 467 2.6E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 PRINTS PR01607 Apyrase family signature 229 252 2.6E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 PRINTS PR01607 Apyrase family signature 206 223 2.6E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 PRINTS PR01607 Apyrase family signature 375 398 2.6E-28 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 Pfam PF00149 Calcineurin-like phosphoesterase 36 246 1.9E-14 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 Pfam PF02872 5'-nucleotidase, C-terminal domain 321 474 4.3E-49 T 13-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CLOST_0281 40c8dcf7eac39fa985a55957d5f4cd7a 592 Gene3D G3DSA:3.90.780.10 321 512 4.3E-65 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CLOST_2172 953b794afc154d3a979e700da97ffd80 132 Pfam PF00411 Ribosomal protein S11 22 131 7.5E-50 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CLOST_2172 953b794afc154d3a979e700da97ffd80 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 132 34.006 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CLOST_2172 953b794afc154d3a979e700da97ffd80 132 Gene3D G3DSA:3.30.420.80 4 132 5.9E-55 T 13-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2172 953b794afc154d3a979e700da97ffd80 132 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 13 129 4.6E-59 T 13-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2172 953b794afc154d3a979e700da97ffd80 132 PIRSF PIRSF002131 1 132 1.3E-52 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CLOST_2172 953b794afc154d3a979e700da97ffd80 132 SUPERFAMILY SSF53137 17 132 4.51E-50 T 13-10-2018 CLOST_2172 953b794afc154d3a979e700da97ffd80 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 100 122 - T 13-10-2018 IPR018102 Ribosomal S11, conserved site CLOST_0334 c7f61725cb63e7aa5df288aaea1514a3 231 Gene3D G3DSA:3.30.470.20 82 218 3.3E-98 T 13-10-2018 CLOST_0334 c7f61725cb63e7aa5df288aaea1514a3 231 Pfam PF01259 SAICAR synthetase 4 229 9.9E-69 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0334 c7f61725cb63e7aa5df288aaea1514a3 231 ProSitePatterns PS01057 SAICAR synthetase signature 1. 83 97 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0334 c7f61725cb63e7aa5df288aaea1514a3 231 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 230 2.1E-75 T 13-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CLOST_0334 c7f61725cb63e7aa5df288aaea1514a3 231 Gene3D G3DSA:3.30.200.20 4 229 3.3E-98 T 13-10-2018 CLOST_0334 c7f61725cb63e7aa5df288aaea1514a3 231 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 231 32.366 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0334 c7f61725cb63e7aa5df288aaea1514a3 231 SUPERFAMILY SSF56104 1 230 7.52E-85 T 13-10-2018 CLOST_0068 44da42c25de322b60c9794f4a9472ccc 525 SUPERFAMILY SSF53098 174 314 4.17E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_0068 44da42c25de322b60c9794f4a9472ccc 525 Pfam PF00665 Integrase core domain 151 275 1.9E-10 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 CLOST_1022 855f84b6388a0484b289a660b600f406 219 Gene3D G3DSA:3.50.40.10 54 199 5.8E-9 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 CLOST_1022 855f84b6388a0484b289a660b600f406 219 SMART SM00873 62 209 5.2E-7 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CLOST_1022 855f84b6388a0484b289a660b600f406 219 Pfam PF03483 B3/4 domain 64 189 1.4E-14 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CLOST_1022 855f84b6388a0484b289a660b600f406 219 SUPERFAMILY SSF56037 59 212 6.28E-21 T 13-10-2018 CLOST_0553 22e621583884454bcf1748d8f4427128 287 Pfam PF01734 Patatin-like phospholipase 6 174 5.1E-19 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CLOST_0553 22e621583884454bcf1748d8f4427128 287 SUPERFAMILY SSF52151 4 275 4.45E-45 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase CLOST_0553 22e621583884454bcf1748d8f4427128 287 Gene3D G3DSA:3.40.1090.10 85 234 9.4E-12 T 13-10-2018 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 356 40.644 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 Pfam PF00472 RF-1 domain 213 320 3.1E-39 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 353 7.1E-164 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 Gene3D G3DSA:3.30.160.20 209 296 9.7E-96 T 13-10-2018 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 Gene3D G3DSA:3.30.70.1660 110 341 9.7E-96 T 13-10-2018 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 Pfam PF03462 PCRF domain 9 202 1.8E-76 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 227 243 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 SMART SM00937 63 177 3.6E-63 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 SUPERFAMILY SSF75620 8 352 2.75E-137 T 13-10-2018 CLOST_2132 d7ad60feb13180b5bb92b50369942b27 356 Gene3D G3DSA:1.20.58.410 1 101 8.0E-10 T 13-10-2018 CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 Gene3D G3DSA:3.40.50.150 79 444 2.1E-100 T 13-10-2018 CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 283 449 1.4E-21 T 13-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 380 410 - T 13-10-2018 IPR030390 RNA methyltransferase TrmA, active site CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 442 6.3E-87 T 13-10-2018 CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 306 324 6.5E-5 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 329 349 6.5E-5 T 13-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 SUPERFAMILY SSF53335 67 448 1.33E-67 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 Gene3D G3DSA:3.40.1350.30 125 285 2.1E-100 T 13-10-2018 CLOST_1195 613ac67735ddaf6a223aa75863d7e9e2 449 Gene3D G3DSA:2.40.50.140 1 77 1.6E-9 T 13-10-2018 CLOST_0963 c3279be45c1923285ed70a653855c0d3 225 SUPERFAMILY SSF51206 12 133 2.09E-21 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like CLOST_0963 c3279be45c1923285ed70a653855c0d3 225 SUPERFAMILY SSF46785 144 220 9.74E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0963 c3279be45c1923285ed70a653855c0d3 225 SMART SM00419 165 213 8.6E-11 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_0963 c3279be45c1923285ed70a653855c0d3 225 Pfam PF00027 Cyclic nucleotide-binding domain 40 113 8.1E-9 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_0963 c3279be45c1923285ed70a653855c0d3 225 Gene3D G3DSA:2.60.120.1460 17 222 1.5E-41 T 13-10-2018 CLOST_0963 c3279be45c1923285ed70a653855c0d3 225 Pfam PF13545 Crp-like helix-turn-helix domain 146 219 3.0E-16 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_2246 80028ec638d9a1c593f78828cb9a9652 157 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 13-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CLOST_2246 80028ec638d9a1c593f78828cb9a9652 157 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 155 6.8E-68 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CLOST_2246 80028ec638d9a1c593f78828cb9a9652 157 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 36.228 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CLOST_2246 80028ec638d9a1c593f78828cb9a9652 157 SUPERFAMILY SSF69765 1 156 1.57E-64 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CLOST_2246 80028ec638d9a1c593f78828cb9a9652 157 Pfam PF02542 YgbB family 1 154 1.3E-64 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CLOST_2246 80028ec638d9a1c593f78828cb9a9652 157 Gene3D G3DSA:3.30.1330.50 1 157 3.9E-66 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CLOST_2020 32fa32bea972d0efc7b392ed7a24dd61 514 SUPERFAMILY SSF51395 31 490 2.78E-27 T 13-10-2018 CLOST_2020 32fa32bea972d0efc7b392ed7a24dd61 514 Gene3D G3DSA:3.20.20.70 194 511 2.7E-29 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_2020 32fa32bea972d0efc7b392ed7a24dd61 514 Pfam PF01645 Conserved region in glutamate synthase 275 404 9.7E-11 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CLOST_2104 e9a5b94830479b425b22640b80796d1c 398 Pfam PF00395 S-layer homology domain 214 256 1.1E-10 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2104 e9a5b94830479b425b22640b80796d1c 398 Pfam PF00395 S-layer homology domain 275 317 2.9E-14 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2104 e9a5b94830479b425b22640b80796d1c 398 Pfam PF00395 S-layer homology domain 347 388 4.4E-6 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2104 e9a5b94830479b425b22640b80796d1c 398 SUPERFAMILY SSF56524 49 155 9.29E-9 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 CLOST_1472 7dff157506149e5fc1a5c7cfa719c936 266 Gene3D G3DSA:3.40.50.970 17 193 1.1E-29 T 13-10-2018 CLOST_1472 7dff157506149e5fc1a5c7cfa719c936 266 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 43 189 4.7E-38 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CLOST_1472 7dff157506149e5fc1a5c7cfa719c936 266 SUPERFAMILY SSF52518 6 221 7.86E-77 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1806 0a1940b2fb5bddac9b7c633195580e81 434 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 174 345 5.4E-29 T 13-10-2018 IPR004477 ComEC/Rec2-related protein CLOST_1806 0a1940b2fb5bddac9b7c633195580e81 434 Pfam PF03772 Competence protein 153 414 1.6E-54 T 13-10-2018 IPR004477 ComEC/Rec2-related protein CLOST_1830 4c78105d0e5166306632318b79814b2c 297 Gene3D G3DSA:3.20.20.70 2 291 2.2E-114 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 Pfam PF00701 Dihydrodipicolinate synthetase family 4 287 2.2E-96 T 13-10-2018 IPR002220 DapA-like GO:0016829 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 287 6.0E-110 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 SMART SM01130 3 290 8.7E-136 T 13-10-2018 IPR002220 DapA-like GO:0016829 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 PIRSF PIRSF001365 1 296 3.2E-96 T 13-10-2018 IPR002220 DapA-like GO:0016829 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 288 63.774 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 1.7E-34 T 13-10-2018 IPR002220 DapA-like GO:0016829 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 1.7E-34 T 13-10-2018 IPR002220 DapA-like GO:0016829 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 1.7E-34 T 13-10-2018 IPR002220 DapA-like GO:0016829 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 1.7E-34 T 13-10-2018 IPR002220 DapA-like GO:0016829 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 SUPERFAMILY SSF51569 1 289 7.75E-103 T 13-10-2018 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 13-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_1830 4c78105d0e5166306632318b79814b2c 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 13-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 SUPERFAMILY SSF46785 665 728 3.05E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 SMART SM00382 416 588 4.6E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 Pfam PF09397 Ftsk gamma domain 667 727 4.1E-27 T 13-10-2018 IPR018541 FtsK gamma domain CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 Gene3D G3DSA:3.30.980.40 274 377 3.4E-36 T 13-10-2018 CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 Gene3D G3DSA:1.10.10.10 658 726 8.6E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 SMART SM00843 665 730 4.4E-31 T 13-10-2018 IPR018541 FtsK gamma domain CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 SUPERFAMILY SSF52540 355 639 5.31E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 Pfam PF01580 FtsK/SpoIIIE family 382 517 8.0E-47 T 13-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CLOST_1683 b7ff638ec92398d7165a4652f89a3865 733 Gene3D G3DSA:3.40.50.300 378 653 7.0E-109 T 13-10-2018 CLOST_0882 6070cef2ffd36c651ff13c887367cf0f 381 Pfam PF00072 Response regulator receiver domain 4 114 5.0E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0882 6070cef2ffd36c651ff13c887367cf0f 381 SUPERFAMILY SSF81606 177 377 1.44E-7 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_0882 6070cef2ffd36c651ff13c887367cf0f 381 SUPERFAMILY SSF52172 1 140 2.28E-33 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0882 6070cef2ffd36c651ff13c887367cf0f 381 Gene3D G3DSA:3.40.50.2300 1 134 3.3E-31 T 13-10-2018 CLOST_0882 6070cef2ffd36c651ff13c887367cf0f 381 SMART SM00331 164 378 4.9E-15 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_0882 6070cef2ffd36c651ff13c887367cf0f 381 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 191 378 8.6E-32 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_0882 6070cef2ffd36c651ff13c887367cf0f 381 SMART SM00448 2 117 1.4E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0882 6070cef2ffd36c651ff13c887367cf0f 381 Gene3D G3DSA:3.60.40.10 135 379 1.1E-43 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_0986 e8153d3bcf3a3bf8f0624292f3cfc6e3 294 Gene3D G3DSA:3.30.230.10 7 144 3.6E-11 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_0986 e8153d3bcf3a3bf8f0624292f3cfc6e3 294 Pfam PF08544 GHMP kinases C terminal 195 253 1.2E-6 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain CLOST_0986 e8153d3bcf3a3bf8f0624292f3cfc6e3 294 SUPERFAMILY SSF55060 176 254 8.02E-5 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CLOST_0986 e8153d3bcf3a3bf8f0624292f3cfc6e3 294 Pfam PF00288 GHMP kinases N terminal domain 76 123 3.4E-5 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CLOST_0986 e8153d3bcf3a3bf8f0624292f3cfc6e3 294 SUPERFAMILY SSF54211 2 136 2.58E-15 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0986 e8153d3bcf3a3bf8f0624292f3cfc6e3 294 PIRSF PIRSF033887 1 282 1.9E-63 T 13-10-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 CLOST_2218 6984db843b1bf90d1b2da7c04db4498a 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.466 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2218 6984db843b1bf90d1b2da7c04db4498a 49 Pfam PF00471 Ribosomal protein L33 3 49 5.1E-23 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2218 6984db843b1bf90d1b2da7c04db4498a 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 7.1E-20 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2218 6984db843b1bf90d1b2da7c04db4498a 49 SUPERFAMILY SSF57829 1 49 1.71E-19 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CLOST_2218 6984db843b1bf90d1b2da7c04db4498a 49 Gene3D G3DSA:2.20.28.120 1 49 1.2E-24 T 13-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2218 6984db843b1bf90d1b2da7c04db4498a 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 13-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_0911 c480eb6e28dbae60d9d78499b4797bba 289 Gene3D G3DSA:3.40.50.150 73 287 7.0E-109 T 13-10-2018 CLOST_0911 c480eb6e28dbae60d9d78499b4797bba 289 Gene3D G3DSA:2.60.40.1180 10 72 7.0E-109 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta CLOST_0911 c480eb6e28dbae60d9d78499b4797bba 289 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 56 204 1.3E-19 T 13-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CLOST_0911 c480eb6e28dbae60d9d78499b4797bba 289 SUPERFAMILY SSF53335 4 251 3.85E-60 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1822 4f79977550083611a229b56b5e6c9123 183 Pfam PF00545 ribonuclease 90 177 1.8E-25 T 13-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CLOST_1822 4f79977550083611a229b56b5e6c9123 183 SUPERFAMILY SSF53933 75 178 2.0E-33 T 13-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CLOST_1822 4f79977550083611a229b56b5e6c9123 183 PRINTS PR00117 Barnase signature 77 94 4.6E-25 T 13-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 CLOST_1822 4f79977550083611a229b56b5e6c9123 183 PRINTS PR00117 Barnase signature 117 135 4.6E-25 T 13-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 CLOST_1822 4f79977550083611a229b56b5e6c9123 183 PRINTS PR00117 Barnase signature 160 178 4.6E-25 T 13-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 CLOST_1822 4f79977550083611a229b56b5e6c9123 183 PRINTS PR00117 Barnase signature 138 157 4.6E-25 T 13-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 CLOST_1822 4f79977550083611a229b56b5e6c9123 183 PRINTS PR00117 Barnase signature 97 114 4.6E-25 T 13-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 CLOST_1822 4f79977550083611a229b56b5e6c9123 183 Gene3D G3DSA:3.10.450.30 65 179 7.1E-44 T 13-10-2018 CLOST_2589 7287b320bbae179b467d8b74ac41a1eb 108 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 5 105 4.6E-26 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CLOST_2589 7287b320bbae179b467d8b74ac41a1eb 108 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 108 16.164 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CLOST_2589 7287b320bbae179b467d8b74ac41a1eb 108 Gene3D G3DSA:3.30.230.10 2 108 2.8E-29 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_2589 7287b320bbae179b467d8b74ac41a1eb 108 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 6 103 1.0E-19 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CLOST_2589 7287b320bbae179b467d8b74ac41a1eb 108 SUPERFAMILY SSF54211 3 106 5.82E-27 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_2589 7287b320bbae179b467d8b74ac41a1eb 108 Pfam PF00825 Ribonuclease P 3 104 1.9E-27 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CLOST_2589 7287b320bbae179b467d8b74ac41a1eb 108 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 49 63 - T 13-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CLOST_1036 e5c3eb18c7ded5bb6dea103c302dad81 341 Gene3D G3DSA:3.40.50.300 1 297 1.3E-24 T 13-10-2018 CLOST_1036 e5c3eb18c7ded5bb6dea103c302dad81 341 SUPERFAMILY SSF52540 1 285 2.0E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1036 e5c3eb18c7ded5bb6dea103c302dad81 341 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 25 281 2.6E-18 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_2311 ebe73e91390185ca096f121262b53361 328 Pfam PF03462 PCRF domain 1 178 8.7E-54 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 CLOST_2311 ebe73e91390185ca096f121262b53361 328 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 324 34.785 T 13-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CLOST_2311 ebe73e91390185ca096f121262b53361 328 SMART SM00937 45 153 2.7E-41 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 CLOST_2311 ebe73e91390185ca096f121262b53361 328 Gene3D G3DSA:3.30.160.20 184 279 3.4E-94 T 13-10-2018 CLOST_2311 ebe73e91390185ca096f121262b53361 328 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 203 219 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CLOST_2311 ebe73e91390185ca096f121262b53361 328 Gene3D G3DSA:3.30.70.1660 88 316 3.4E-94 T 13-10-2018 CLOST_2311 ebe73e91390185ca096f121262b53361 328 SUPERFAMILY SSF75620 1 324 1.57E-125 T 13-10-2018 CLOST_2311 ebe73e91390185ca096f121262b53361 328 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 322 1.0E-144 T 13-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CLOST_2311 ebe73e91390185ca096f121262b53361 328 Gene3D G3DSA:1.20.58.410 1 81 4.6E-15 T 13-10-2018 CLOST_2311 ebe73e91390185ca096f121262b53361 328 Pfam PF00472 RF-1 domain 187 296 9.9E-43 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CLOST_1651 694d520b2e47efeccde0f046c3e0af39 216 Gene3D G3DSA:1.10.3720.10 2 216 3.7E-47 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1651 694d520b2e47efeccde0f046c3e0af39 216 SUPERFAMILY SSF161098 7 202 2.22E-43 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1651 694d520b2e47efeccde0f046c3e0af39 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 202 3.2E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_1804 247d30e418ccdc7a1fcc210bca3cf070 89 Pfam PF01649 Ribosomal protein S20 2 84 8.7E-25 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1804 247d30e418ccdc7a1fcc210bca3cf070 89 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 16 80 8.0E-14 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1804 247d30e418ccdc7a1fcc210bca3cf070 89 SUPERFAMILY SSF46992 3 86 9.16E-26 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1804 247d30e418ccdc7a1fcc210bca3cf070 89 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 3.4E-23 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1804 247d30e418ccdc7a1fcc210bca3cf070 89 Gene3D G3DSA:1.20.58.110 1 86 4.5E-25 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1804 247d30e418ccdc7a1fcc210bca3cf070 89 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.213 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1086 3443e9334ea9397b8c90690655849041 235 Pfam PF13367 Protease prsW family 29 206 7.9E-39 T 13-10-2018 IPR026898 Protease PrsW GO:0008233 CLOST_1086 3443e9334ea9397b8c90690655849041 235 PIRSF PIRSF016933 2 230 5.8E-71 T 13-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 CLOST_0989 f962386142046c1177ef7f6fce99a03b 213 SUPERFAMILY SSF53790 1 205 5.5E-37 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 CLOST_0989 f962386142046c1177ef7f6fce99a03b 213 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 203 1.5E-47 T 13-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CLOST_0989 f962386142046c1177ef7f6fce99a03b 213 Gene3D G3DSA:3.40.1010.10 1 108 2.8E-24 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 CLOST_0989 f962386142046c1177ef7f6fce99a03b 213 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 192 1.4E-26 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 CLOST_1346 53ade4bfaed913ee2f93153fb15f8faf 69 Pfam PF02609 Exonuclease VII small subunit 9 58 5.0E-17 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CLOST_1346 53ade4bfaed913ee2f93153fb15f8faf 69 SUPERFAMILY SSF116842 2 66 1.7E-18 T 13-10-2018 CLOST_1346 53ade4bfaed913ee2f93153fb15f8faf 69 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 8 62 6.5E-19 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CLOST_1346 53ade4bfaed913ee2f93153fb15f8faf 69 PIRSF PIRSF006488 1 66 2.5E-18 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CLOST_1346 53ade4bfaed913ee2f93153fb15f8faf 69 Gene3D G3DSA:1.10.287.1040 1 67 2.6E-19 T 13-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 CLOST_1346 53ade4bfaed913ee2f93153fb15f8faf 69 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 7 67 13.192 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CLOST_0916 3c3b4d5dd81398daf97d83433222365d 316 SUPERFAMILY SSF102114 9 287 1.15E-45 T 13-10-2018 CLOST_0916 3c3b4d5dd81398daf97d83433222365d 316 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 306 5.7E-90 T 13-10-2018 IPR005911 Protein YhcC-like GO:0051536 CLOST_0916 3c3b4d5dd81398daf97d83433222365d 316 Pfam PF16199 Radical_SAM C-terminal domain 212 294 6.7E-20 T 13-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CLOST_0916 3c3b4d5dd81398daf97d83433222365d 316 Pfam PF04055 Radical SAM superfamily 36 202 9.1E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0916 3c3b4d5dd81398daf97d83433222365d 316 Gene3D G3DSA:3.80.30.20 8 294 3.3E-17 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_0916 3c3b4d5dd81398daf97d83433222365d 316 SMART SM00729 23 251 2.6E-33 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1808 3700b51b0d998499f5fa4e0e8a649054 387 Gene3D G3DSA:3.40.630.30 2 129 8.5E-25 T 13-10-2018 CLOST_1808 3700b51b0d998499f5fa4e0e8a649054 387 SUPERFAMILY SSF55729 3 287 8.1E-55 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1808 3700b51b0d998499f5fa4e0e8a649054 387 Gene3D G3DSA:3.40.630.30 130 288 1.0E-24 T 13-10-2018 CLOST_1808 3700b51b0d998499f5fa4e0e8a649054 387 SUPERFAMILY SSF55718 288 387 1.38E-15 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily CLOST_1808 3700b51b0d998499f5fa4e0e8a649054 387 Pfam PF13530 Sterol carrier protein domain 177 383 6.5E-36 T 13-10-2018 IPR025559 Enhanced intracellular survival protein domain CLOST_1808 3700b51b0d998499f5fa4e0e8a649054 387 Gene3D G3DSA:3.30.1050.10 289 378 5.6E-12 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily CLOST_1808 3700b51b0d998499f5fa4e0e8a649054 387 Pfam PF13527 Acetyltransferase (GNAT) domain 3 125 1.5E-27 T 13-10-2018 CLOST_1667 9a438b313afdad0567dab689a2c07393 95 Pfam PF02553 Cobalt transport protein component CbiN 8 72 2.4E-27 T 13-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CLOST_1667 9a438b313afdad0567dab689a2c07393 95 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 95 42.14 T 13-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CLOST_0211 9e8883a2192261ac402013ad14c9566d 418 Pfam PF07075 Protein of unknown function (DUF1343) 72 417 3.9E-108 T 13-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 CLOST_0211 9e8883a2192261ac402013ad14c9566d 418 PIRSF PIRSF016719 23 418 2.3E-112 T 13-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 CLOST_0211 9e8883a2192261ac402013ad14c9566d 418 Gene3D G3DSA:3.40.50.12170 55 417 3.9E-115 T 13-10-2018 CLOST_0211 9e8883a2192261ac402013ad14c9566d 418 Gene3D G3DSA:3.90.1150.140 265 402 3.9E-115 T 13-10-2018 CLOST_1776 dee57e85384f12825b831854ba1ac107 233 Pfam PF01569 PAP2 superfamily 139 232 3.9E-9 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOST_1776 dee57e85384f12825b831854ba1ac107 233 Pfam PF01219 Prokaryotic diacylglycerol kinase 12 113 1.9E-34 T 13-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CLOST_1776 dee57e85384f12825b831854ba1ac107 233 Gene3D G3DSA:1.20.144.10 158 233 4.5E-8 T 13-10-2018 CLOST_1776 dee57e85384f12825b831854ba1ac107 233 SUPERFAMILY SSF48317 47 232 7.72E-11 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily CLOST_1776 dee57e85384f12825b831854ba1ac107 233 Gene3D G3DSA:1.10.3830.10 2 118 6.0E-37 T 13-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CLOST_1921 3e5012a7b2128820f5345d73bab680ac 360 Pfam PF00155 Aminotransferase class I and II 23 354 3.5E-43 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_1921 3e5012a7b2128820f5345d73bab680ac 360 Gene3D G3DSA:3.40.640.10 36 260 3.4E-95 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1921 3e5012a7b2128820f5345d73bab680ac 360 Gene3D G3DSA:3.90.1150.10 24 354 3.4E-95 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1921 3e5012a7b2128820f5345d73bab680ac 360 SUPERFAMILY SSF53383 4 357 7.6E-67 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 Pfam PF08245 Mur ligase middle domain 44 270 2.1E-16 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 Gene3D G3DSA:3.40.1190.10 1 297 3.2E-100 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 427 1.9E-122 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 Pfam PF02875 Mur ligase family, glutamate ligase domain 296 366 1.2E-7 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 SUPERFAMILY SSF53623 1 296 9.39E-92 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 Gene3D G3DSA:3.90.190.20 298 434 3.4E-37 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 PIRSF PIRSF001563 1 434 7.8E-145 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 SUPERFAMILY SSF53244 298 430 3.66E-29 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 42 65 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CLOST_0623 f1c1f57f047ea53dcebd04c8b030ea86 435 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 140 155 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CLOST_0080 56b8d6868a1660ee9bb6c17763ddd314 343 Gene3D G3DSA:3.20.20.210 1 336 4.7E-73 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0080 56b8d6868a1660ee9bb6c17763ddd314 343 SUPERFAMILY SSF51726 1 336 4.84E-65 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0080 56b8d6868a1660ee9bb6c17763ddd314 343 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 3 335 4.8E-75 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CLOST_2481 bf0bfebdc5e1e293317d95b1e277574e 248 SUPERFAMILY SSF55811 34 179 3.25E-24 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 CLOST_2481 bf0bfebdc5e1e293317d95b1e277574e 248 Gene3D G3DSA:3.90.79.10 2 171 1.5E-35 T 13-10-2018 CLOST_2481 bf0bfebdc5e1e293317d95b1e277574e 248 SUPERFAMILY SSF46785 183 245 3.81E-10 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2481 bf0bfebdc5e1e293317d95b1e277574e 248 Gene3D G3DSA:1.10.10.10 175 248 6.8E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2481 bf0bfebdc5e1e293317d95b1e277574e 248 Pfam PF00293 NUDIX domain 37 137 4.2E-11 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CLOST_2285 b195dc46548de430761dfb5b867c12e0 1583 Gene3D G3DSA:2.60.40.10 887 989 2.5E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold CLOST_2285 b195dc46548de430761dfb5b867c12e0 1583 SUPERFAMILY SSF49265 893 996 5.09E-7 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 CLOST_2285 b195dc46548de430761dfb5b867c12e0 1583 Pfam PF00395 S-layer homology domain 1463 1504 4.3E-6 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2285 b195dc46548de430761dfb5b867c12e0 1583 Pfam PF00395 S-layer homology domain 1530 1572 0.003 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2285 b195dc46548de430761dfb5b867c12e0 1583 Pfam PF00395 S-layer homology domain 1404 1445 6.1E-10 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 SMART SM00421 154 211 6.8E-20 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 171 198 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 Pfam PF00072 Response regulator receiver domain 6 119 7.2E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 Gene3D G3DSA:3.40.50.12740 4 217 5.9E-57 T 13-10-2018 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 SUPERFAMILY SSF46894 150 217 3.74E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 SUPERFAMILY SSF52172 1 128 2.28E-32 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 4.7E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 4.7E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 4.7E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 208 8.6E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2327 6c54a775eb95d022eee937ce21bf8632 222 SMART SM00448 4 119 1.6E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0300 6c03d88aa02540ecb3dc487c7afcbbb7 376 Pfam PF00589 Phage integrase family 173 341 1.8E-22 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CLOST_0300 6c03d88aa02540ecb3dc487c7afcbbb7 376 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 58 115 4.5E-21 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CLOST_0300 6c03d88aa02540ecb3dc487c7afcbbb7 376 Gene3D G3DSA:1.10.150.130 55 165 1.7E-20 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal CLOST_0300 6c03d88aa02540ecb3dc487c7afcbbb7 376 Gene3D G3DSA:1.10.443.10 166 356 5.4E-42 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CLOST_0300 6c03d88aa02540ecb3dc487c7afcbbb7 376 SUPERFAMILY SSF56349 57 348 4.12E-61 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CLOST_0300 6c03d88aa02540ecb3dc487c7afcbbb7 376 Pfam PF14657 Arm DNA-binding domain 12 55 3.8E-12 T 13-10-2018 IPR028259 AP2-like integrase, N-terminal domain CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 Gene3D G3DSA:3.30.930.10 99 418 9.9E-102 T 13-10-2018 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 1.4E-19 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 1.4E-19 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 1.4E-19 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 1.4E-19 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 Pfam PF01336 OB-fold nucleic acid binding domain 17 87 9.8E-15 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 14 429 8.4E-129 T 13-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 429 39.153 T 13-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 Gene3D G3DSA:2.40.50.140 1 98 1.2E-25 T 13-10-2018 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 SUPERFAMILY SSF55681 97 426 1.52E-79 T 13-10-2018 CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 SUPERFAMILY SSF50249 5 98 2.4E-21 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2424 957c9e67edaed98612dcfee221de3a23 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 423 2.8E-78 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1607 ab2a5ec3195dd6db41288e9508e49777 266 Gene3D G3DSA:3.40.190.10 38 255 1.7E-65 T 13-10-2018 CLOST_1607 ab2a5ec3195dd6db41288e9508e49777 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 256 1.3E-50 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_1607 ab2a5ec3195dd6db41288e9508e49777 266 SMART SM00062 40 265 1.3E-48 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_1607 ab2a5ec3195dd6db41288e9508e49777 266 SUPERFAMILY SSF53850 1 256 6.64E-57 T 13-10-2018 CLOST_1607 ab2a5ec3195dd6db41288e9508e49777 266 Gene3D G3DSA:3.40.190.10 131 222 1.7E-65 T 13-10-2018 CLOST_0697 ed3e32c8bf79dd2b7d764ec9d5d12e02 486 SUPERFAMILY SSF102114 236 440 1.96E-23 T 13-10-2018 CLOST_0697 ed3e32c8bf79dd2b7d764ec9d5d12e02 486 SMART SM00729 242 447 2.8E-15 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0697 ed3e32c8bf79dd2b7d764ec9d5d12e02 486 Gene3D G3DSA:3.80.30.20 239 449 5.3E-12 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1049 3c48a6d41236f3379605afb12a5010e9 365 SUPERFAMILY SSF46785 273 353 7.06E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1049 3c48a6d41236f3379605afb12a5010e9 365 Gene3D G3DSA:1.10.10.10 255 361 1.2E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1049 3c48a6d41236f3379605afb12a5010e9 365 SMART SM00418 279 353 6.1E-6 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_1049 3c48a6d41236f3379605afb12a5010e9 365 Pfam PF01022 Bacterial regulatory protein, arsR family 286 325 2.5E-8 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_1612 f63cce780581ddceaec5d1eac1d04722 127 Gene3D G3DSA:1.10.10.10 9 123 1.3E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1612 f63cce780581ddceaec5d1eac1d04722 127 SMART SM00345 16 75 5.3E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_1612 f63cce780581ddceaec5d1eac1d04722 127 SUPERFAMILY SSF46785 5 77 9.5E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1612 f63cce780581ddceaec5d1eac1d04722 127 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.4E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_0354 cd4e5954e670ecde809ad4ac3bbbde6a 381 Pfam PF02321 Outer membrane efflux protein 96 196 6.3E-5 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 CLOST_0354 cd4e5954e670ecde809ad4ac3bbbde6a 381 SUPERFAMILY SSF56954 32 364 2.22E-11 T 13-10-2018 CLOST_0354 cd4e5954e670ecde809ad4ac3bbbde6a 381 Gene3D G3DSA:1.20.1600.10 40 371 5.8E-10 T 13-10-2018 CLOST_0442 db82a13fe71a5ddf5480578c262ffb3b 337 SUPERFAMILY SSF53383 32 332 5.16E-11 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0991 ccb3ee917a0626723fb31ff060649095 233 PIRSF PIRSF036427 1 233 3.8E-69 T 13-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 CLOST_0991 ccb3ee917a0626723fb31ff060649095 233 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 4 229 8.3E-69 T 13-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CLOST_0991 ccb3ee917a0626723fb31ff060649095 233 SUPERFAMILY SSF53790 4 229 2.22E-36 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 CLOST_0991 ccb3ee917a0626723fb31ff060649095 233 Gene3D G3DSA:3.40.1010.10 2 127 2.0E-28 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 CLOST_0991 ccb3ee917a0626723fb31ff060649095 233 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 2.5E-41 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 CLOST_0991 ccb3ee917a0626723fb31ff060649095 233 Gene3D G3DSA:3.30.950.10 128 232 4.2E-16 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 CLOST_1418 3ee63721cb867472eeaa3332ec6d3ca3 311 Pfam PF00348 Polyprenyl synthetase 25 258 4.7E-53 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 CLOST_1418 3ee63721cb867472eeaa3332ec6d3ca3 311 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 90 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site CLOST_1418 3ee63721cb867472eeaa3332ec6d3ca3 311 SUPERFAMILY SSF48576 10 310 1.1E-62 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily CLOST_1418 3ee63721cb867472eeaa3332ec6d3ca3 311 Gene3D G3DSA:1.10.600.10 2 311 1.4E-69 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily CLOST_1655 397291f97f0fe4f88035c2cd192d0806 144 Pfam PF00293 NUDIX domain 9 126 3.2E-20 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CLOST_1655 397291f97f0fe4f88035c2cd192d0806 144 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CLOST_1655 397291f97f0fe4f88035c2cd192d0806 144 SUPERFAMILY SSF55811 6 133 1.18E-27 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 CLOST_1655 397291f97f0fe4f88035c2cd192d0806 144 PRINTS PR00502 NUDIX hydrolase family signature 27 41 5.1E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CLOST_1655 397291f97f0fe4f88035c2cd192d0806 144 PRINTS PR00502 NUDIX hydrolase family signature 41 56 5.1E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CLOST_1655 397291f97f0fe4f88035c2cd192d0806 144 Gene3D G3DSA:3.90.79.10 5 139 2.6E-31 T 13-10-2018 CLOST_1655 397291f97f0fe4f88035c2cd192d0806 144 ProDom PD037294 PEPTIDE ACMNPV ORF38 ORF ORF_59 ORF61 ORF7 PXORF52 ORF-30 ORF79 29 85 0.002 T 13-10-2018 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 Pfam PF01316 Arginine repressor, DNA binding domain 2 65 6.9E-23 T 13-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 86 148 3.0E-8 T 13-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 SUPERFAMILY SSF46785 2 76 8.55E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 Gene3D G3DSA:3.30.1360.40 68 148 7.8E-22 T 13-10-2018 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 Gene3D G3DSA:1.10.10.10 1 62 5.0E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 PRINTS PR01467 Bacterial arginine repressor signature 20 33 6.4E-19 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 PRINTS PR01467 Bacterial arginine repressor signature 36 51 6.4E-19 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 PRINTS PR01467 Bacterial arginine repressor signature 87 100 6.4E-19 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 PRINTS PR01467 Bacterial arginine repressor signature 117 132 6.4E-19 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 Pfam PF02863 Arginine repressor, C-terminal domain 80 144 1.7E-21 T 13-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 TIGRFAM TIGR01529 argR_whole: arginine repressor 3 148 1.6E-42 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 SUPERFAMILY SSF55252 79 147 4.84E-16 T 13-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 CLOST_1341 2eca9616c07a9ffb7e2a5c351081e471 148 Hamap MF_00173 Arginine repressor [argR]. 1 148 54.632 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CLOST_2290 e690846e0405090323c163cb75354244 636 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2290 e690846e0405090323c163cb75354244 636 SUPERFAMILY SSF52540 313 516 3.36E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2290 e690846e0405090323c163cb75354244 636 Pfam PF00005 ABC transporter 20 187 8.1E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2290 e690846e0405090323c163cb75354244 636 Pfam PF12848 ABC transporter 226 300 1.5E-8 T 13-10-2018 IPR032781 ABC-transporter extension domain CLOST_2290 e690846e0405090323c163cb75354244 636 Gene3D G3DSA:3.40.50.300 2 281 7.7E-62 T 13-10-2018 CLOST_2290 e690846e0405090323c163cb75354244 636 Gene3D G3DSA:3.40.50.300 282 551 1.8E-59 T 13-10-2018 CLOST_2290 e690846e0405090323c163cb75354244 636 SMART SM00382 343 522 4.7E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2290 e690846e0405090323c163cb75354244 636 SMART SM00382 28 238 4.1E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2290 e690846e0405090323c163cb75354244 636 Gene3D G3DSA:1.10.287.380 552 632 3.5E-7 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CLOST_2290 e690846e0405090323c163cb75354244 636 Pfam PF16326 ABC transporter C-terminal domain 562 628 3.5E-14 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CLOST_2290 e690846e0405090323c163cb75354244 636 SUPERFAMILY SSF52540 5 237 7.22E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2290 e690846e0405090323c163cb75354244 636 Pfam PF00005 ABC transporter 334 469 3.0E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0683 1d33b1f6c4389012afe5fb4e094e7151 278 Gene3D G3DSA:3.30.30.40 118 154 5.6E-67 T 13-10-2018 CLOST_0683 1d33b1f6c4389012afe5fb4e094e7151 278 Pfam PF01144 Coenzyme A transferase 7 225 3.2E-29 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 CLOST_0683 1d33b1f6c4389012afe5fb4e094e7151 278 Gene3D G3DSA:3.40.1080.10 8 265 5.6E-67 T 13-10-2018 CLOST_0683 1d33b1f6c4389012afe5fb4e094e7151 278 SMART SM00882 6 226 9.3E-25 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 CLOST_0683 1d33b1f6c4389012afe5fb4e094e7151 278 SUPERFAMILY SSF100950 4 271 1.86E-61 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_1192 8d88e942036e56c2b385c93a0e3b2edd 311 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 308 3.6E-113 T 13-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CLOST_1192 8d88e942036e56c2b385c93a0e3b2edd 311 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 307 7.4E-103 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CLOST_1192 8d88e942036e56c2b385c93a0e3b2edd 311 Gene3D G3DSA:3.20.20.70 1 311 2.7E-129 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1192 8d88e942036e56c2b385c93a0e3b2edd 311 SUPERFAMILY SSF51569 3 307 1.04E-107 T 13-10-2018 CLOST_1192 8d88e942036e56c2b385c93a0e3b2edd 311 PIRSF PIRSF001359 1 309 1.2E-105 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CLOST_1192 8d88e942036e56c2b385c93a0e3b2edd 311 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 84 - T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CLOST_1192 8d88e942036e56c2b385c93a0e3b2edd 311 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 305 3.8E-94 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 SUPERFAMILY SSF50249 2 66 1.58E-12 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 Pfam PF03193 RsgA GTPase 63 227 5.8E-56 T 13-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 Gene3D G3DSA:1.10.40.50 229 297 1.5E-20 T 13-10-2018 CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 41 286 7.1E-71 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 Gene3D G3DSA:3.40.50.300 64 227 4.0E-41 T 13-10-2018 CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 Gene3D G3DSA:2.40.50.140 1 63 4.8E-22 T 13-10-2018 CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 SUPERFAMILY SSF52540 70 290 1.28E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 293 34.512 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CLOST_1848 fb7778255b9f0d6dc9b260977a99a033 297 Pfam PF16745 RsgA N-terminal domain 3 51 7.1E-19 T 13-10-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Pfam PF00562 RNA polymerase Rpb2, domain 6 690 1076 4.8E-169 T 13-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Pfam PF04565 RNA polymerase Rpb2, domain 3 483 551 1.9E-31 T 13-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 1 1154 12.515 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 207 903 3.4E-300 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 ProSitePatterns PS01166 RNA polymerases beta chain signature. 929 941 - T 13-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Gene3D G3DSA:2.40.270.10 919 1062 5.4E-53 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Gene3D G3DSA:2.40.50.150 796 918 1.7E-53 T 13-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Pfam PF04561 RNA polymerase Rpb2, domain 2 353 424 1.8E-5 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Pfam PF04561 RNA polymerase Rpb2, domain 2 133 279 1.9E-22 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Pfam PF04560 RNA polymerase Rpb2, domain 7 1078 1153 7.5E-28 T 13-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Gene3D G3DSA:3.90.1100.10 614 686 1.3E-19 T 13-10-2018 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Gene3D G3DSA:2.40.50.100 687 761 9.4E-32 T 13-10-2018 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Gene3D G3DSA:3.90.1800.10 1064 1117 2.5E-10 T 13-10-2018 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 SUPERFAMILY SSF64484 3 1162 0.0 T 13-10-2018 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Gene3D G3DSA:3.90.1110.10 135 302 7.6E-59 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Pfam PF04563 RNA polymerase beta subunit 14 470 3.1E-27 T 13-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Gene3D G3DSA:3.90.1100.10 351 613 1.5E-75 T 13-10-2018 CLOST_2211 c1f82ce515e7791c01a5b312bb699967 1223 Pfam PF10385 RNA polymerase beta subunit external 1 domain 561 629 3.0E-18 T 13-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_0428 54a8c34dcdf9a9b16e52b68c9be3d9fb 447 PIRSF PIRSF006815 2 447 2.8E-190 T 13-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CLOST_0428 54a8c34dcdf9a9b16e52b68c9be3d9fb 447 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 2 446 47.846 T 13-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CLOST_0428 54a8c34dcdf9a9b16e52b68c9be3d9fb 447 SUPERFAMILY SSF53383 2 443 1.52E-111 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0428 54a8c34dcdf9a9b16e52b68c9be3d9fb 447 Gene3D G3DSA:3.90.1150.10 72 442 4.0E-159 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0428 54a8c34dcdf9a9b16e52b68c9be3d9fb 447 Gene3D G3DSA:3.40.640.10 83 348 4.0E-159 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0428 54a8c34dcdf9a9b16e52b68c9be3d9fb 447 Pfam PF02347 Glycine cleavage system P-protein 4 442 2.6E-142 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CLOST_1161 82cd45124931ab58fdc303b19ecfc1d2 260 SUPERFAMILY SSF52540 1 238 9.38E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1161 82cd45124931ab58fdc303b19ecfc1d2 260 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 232 1.6E-20 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOST_1161 82cd45124931ab58fdc303b19ecfc1d2 260 Gene3D G3DSA:3.40.50.300 1 256 1.4E-61 T 13-10-2018 CLOST_1161 82cd45124931ab58fdc303b19ecfc1d2 260 PIRSF PIRSF005647 1 257 3.2E-81 T 13-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type CLOST_0272 2ddbc689ac21b668e95cbeb8a40c015f 143 Pfam PF00582 Universal stress protein family 4 141 2.4E-32 T 13-10-2018 IPR006016 UspA CLOST_0272 2ddbc689ac21b668e95cbeb8a40c015f 143 PRINTS PR01438 Universal stress protein signature 3 21 7.8E-16 T 13-10-2018 IPR006015 Universal stress protein A CLOST_0272 2ddbc689ac21b668e95cbeb8a40c015f 143 PRINTS PR01438 Universal stress protein signature 119 141 7.8E-16 T 13-10-2018 IPR006015 Universal stress protein A CLOST_0272 2ddbc689ac21b668e95cbeb8a40c015f 143 PRINTS PR01438 Universal stress protein signature 101 113 7.8E-16 T 13-10-2018 IPR006015 Universal stress protein A CLOST_0272 2ddbc689ac21b668e95cbeb8a40c015f 143 Gene3D G3DSA:3.40.50.620 2 141 9.4E-37 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0272 2ddbc689ac21b668e95cbeb8a40c015f 143 SUPERFAMILY SSF52402 4 141 5.02E-36 T 13-10-2018 CLOST_0214 d8f1164f30be33d920608e7cf24a4631 787 Pfam PF02687 FtsX-like permease family 292 375 1.2E-7 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CLOST_0214 d8f1164f30be33d920608e7cf24a4631 787 Pfam PF02687 FtsX-like permease family 686 778 3.3E-10 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 Gene3D G3DSA:1.10.580.10 63 418 5.6E-107 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 Gene3D G3DSA:1.10.230.10 275 393 5.6E-107 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 PRINTS PR00143 Citrate synthase signature 226 241 1.1E-30 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 PRINTS PR00143 Citrate synthase signature 379 395 1.1E-30 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 PRINTS PR00143 Citrate synthase signature 170 183 1.1E-30 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 PRINTS PR00143 Citrate synthase signature 249 277 1.1E-30 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 PRINTS PR00143 Citrate synthase signature 399 413 1.1E-30 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 SUPERFAMILY SSF48256 39 435 1.7E-92 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 CLOST_1244 5064691ce07bc8a6dabe4df553f9edea 446 Pfam PF00285 Citrate synthase, C-terminal domain 38 430 1.2E-111 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 CLOST_0073 3787f1224132170cc16bb7a9487b18bc 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 267 6.8E-25 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0073 3787f1224132170cc16bb7a9487b18bc 289 SUPERFAMILY SSF161098 78 264 1.03E-31 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0073 3787f1224132170cc16bb7a9487b18bc 289 Gene3D G3DSA:1.10.3720.10 80 271 5.4E-25 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2072 8f62873f29850bf4a1c4ec97743ad934 325 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 239 323 9.7E-31 T 13-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CLOST_2072 8f62873f29850bf4a1c4ec97743ad934 325 SUPERFAMILY SSF82649 238 324 5.75E-26 T 13-10-2018 CLOST_2072 8f62873f29850bf4a1c4ec97743ad934 325 Gene3D G3DSA:3.30.930.10 1 237 2.7E-78 T 13-10-2018 CLOST_2072 8f62873f29850bf4a1c4ec97743ad934 325 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 4 315 2.0E-101 T 13-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CLOST_2072 8f62873f29850bf4a1c4ec97743ad934 325 SUPERFAMILY SSF55681 1 237 6.53E-76 T 13-10-2018 CLOST_2072 8f62873f29850bf4a1c4ec97743ad934 325 Gene3D G3DSA:3.30.390.50 238 325 7.2E-30 T 13-10-2018 CLOST_2072 8f62873f29850bf4a1c4ec97743ad934 325 Pfam PF03099 Biotin/lipoate A/B protein ligase family 44 149 1.7E-9 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CLOST_2545 37942cab27fb5904a34dc8d1d5db6681 296 Pfam PF00892 EamA-like transporter family 20 147 2.5E-20 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_2545 37942cab27fb5904a34dc8d1d5db6681 296 Pfam PF00892 EamA-like transporter family 157 289 5.1E-19 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_2545 37942cab27fb5904a34dc8d1d5db6681 296 SUPERFAMILY SSF103481 192 293 6.15E-13 T 13-10-2018 CLOST_2545 37942cab27fb5904a34dc8d1d5db6681 296 SUPERFAMILY SSF103481 51 149 4.05E-13 T 13-10-2018 CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 32 461 3.1E-155 T 13-10-2018 CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 272 466 1.4E-22 T 13-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 SUPERFAMILY SSF50249 13 75 2.01E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 SUPERFAMILY SSF53335 83 466 7.15E-86 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 Pfam PF01938 TRAM domain 21 74 3.4E-10 T 13-10-2018 IPR002792 TRAM domain CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 Gene3D G3DSA:3.40.50.150 97 463 1.5E-120 T 13-10-2018 CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 399 430 - T 13-10-2018 IPR030390 RNA methyltransferase TrmA, active site CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 Gene3D G3DSA:2.40.50.140 11 95 9.1E-21 T 13-10-2018 CLOST_1643 520e1e0517a29cf04a7e7f39ca520040 475 Gene3D G3DSA:3.40.1350.30 144 300 1.5E-120 T 13-10-2018 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Gene3D G3DSA:1.20.120.1810 100 137 4.0E-9 T 13-10-2018 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Gene3D G3DSA:1.10.10.10 216 291 1.7E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 SUPERFAMILY SSF88659 273 375 5.05E-30 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 SUPERFAMILY SSF88659 216 290 9.16E-23 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Gene3D G3DSA:1.10.10.10 293 376 1.3E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 PRINTS PR00046 Major sigma-70 factor signature 167 180 8.1E-32 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 PRINTS PR00046 Major sigma-70 factor signature 191 199 8.1E-32 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 PRINTS PR00046 Major sigma-70 factor signature 336 351 8.1E-32 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 PRINTS PR00046 Major sigma-70 factor signature 351 362 8.1E-32 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 PRINTS PR00046 Major sigma-70 factor signature 315 327 8.1E-32 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 SUPERFAMILY SSF88946 104 213 6.54E-53 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Pfam PF04539 Sigma-70 region 3 222 298 6.7E-31 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Gene3D G3DSA:1.10.220.120 5 67 2.9E-13 T 13-10-2018 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 167 180 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 139 375 9.7E-125 T 13-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Pfam PF04545 Sigma-70, region 4 312 364 5.6E-19 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Gene3D G3DSA:1.10.601.10 138 215 1.8E-51 T 13-10-2018 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 336 362 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Pfam PF04542 Sigma-70 region 2 143 212 8.7E-23 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Pfam PF03979 Sigma-70 factor, region 1.1 8 88 4.3E-19 T 13-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 3 376 33.981 T 13-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 140 364 8.9E-39 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 CLOST_1755 fa3bc7ac260eb604ad165e10193dfd8a 376 Pfam PF00140 Sigma-70 factor, region 1.2 105 137 1.3E-15 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 1.1E-58 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 34.97 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 SUPERFAMILY SSF52374 3 151 1.02E-42 T 13-10-2018 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 3 78 6.0E-4 T 13-10-2018 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 Gene3D G3DSA:3.40.50.620 1 161 6.4E-55 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 4.5E-19 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 Pfam PF01467 Cytidylyltransferase-like 6 134 9.9E-19 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 2.7E-49 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 2.7E-49 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 2.7E-49 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 2.7E-49 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CLOST_1839 4f65e3428c632327c84243f6ff1603b8 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 2.7E-49 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CLOST_1516 2cbbca405bded18b574a7bf6ad3c7f95 217 Gene3D G3DSA:3.10.350.10 157 217 1.2E-16 T 13-10-2018 IPR036779 LysM domain superfamily CLOST_1516 2cbbca405bded18b574a7bf6ad3c7f95 217 SMART SM00257 168 213 5.6E-15 T 13-10-2018 IPR018392 LysM domain CLOST_1516 2cbbca405bded18b574a7bf6ad3c7f95 217 SUPERFAMILY SSF54106 168 214 2.75E-10 T 13-10-2018 CLOST_1516 2cbbca405bded18b574a7bf6ad3c7f95 217 Pfam PF01476 LysM domain 169 213 6.5E-14 T 13-10-2018 IPR018392 LysM domain CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 32 48 3.4E-14 T 13-10-2018 IPR002177 DNA-binding protein Dps CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 128 146 3.4E-14 T 13-10-2018 IPR002177 DNA-binding protein Dps CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 56 72 3.4E-14 T 13-10-2018 IPR002177 DNA-binding protein Dps CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 PIRSF PIRSF005900 1 151 4.0E-51 T 13-10-2018 IPR002177 DNA-binding protein Dps CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 Pfam PF00210 Ferritin-like domain 13 150 1.1E-32 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 SUPERFAMILY SSF47240 9 150 9.32E-46 T 13-10-2018 IPR009078 Ferritin-like superfamily CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 Gene3D G3DSA:1.20.1260.10 1 151 5.9E-57 T 13-10-2018 IPR012347 Ferritin-like CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 ProSitePatterns PS00819 Dps protein family signature 2. 58 72 - T 13-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CLOST_0156 0822a0676b1b8b7a3097ff214d077d1f 151 ProSitePatterns PS00818 Dps protein family signature 1. 32 48 - T 13-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CLOST_2167 b8f7b91dcad731a99e7ef72683b2bea0 276 SMART SM00382 33 219 1.5E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2167 b8f7b91dcad731a99e7ef72683b2bea0 276 Pfam PF00005 ABC transporter 25 171 2.9E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2167 b8f7b91dcad731a99e7ef72683b2bea0 276 Gene3D G3DSA:3.40.50.300 3 276 1.3E-74 T 13-10-2018 CLOST_2167 b8f7b91dcad731a99e7ef72683b2bea0 276 SUPERFAMILY SSF52540 4 232 8.17E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2167 b8f7b91dcad731a99e7ef72683b2bea0 276 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 5 275 1.7E-122 T 13-10-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CLOST_2167 b8f7b91dcad731a99e7ef72683b2bea0 276 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2148 d97884dd3455057bbfed523106c38785 589 SUPERFAMILY SSF53633 306 583 3.27E-57 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_2148 d97884dd3455057bbfed523106c38785 589 ProSitePatterns PS00324 Aspartokinase signature. 308 316 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 CLOST_2148 d97884dd3455057bbfed523106c38785 589 SUPERFAMILY SSF52317 18 296 4.58E-87 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_2148 d97884dd3455057bbfed523106c38785 589 Pfam PF04204 Homoserine O-succinyltransferase 6 298 3.3E-117 T 13-10-2018 IPR033752 MetA family CLOST_2148 d97884dd3455057bbfed523106c38785 589 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 16 300 1.9E-114 T 13-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 CLOST_2148 d97884dd3455057bbfed523106c38785 589 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 288 1.0E-75 T 13-10-2018 CLOST_2148 d97884dd3455057bbfed523106c38785 589 Gene3D G3DSA:3.40.1160.10 304 584 1.8E-82 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_2148 d97884dd3455057bbfed523106c38785 589 Pfam PF00696 Amino acid kinase family 306 571 2.9E-37 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 CLOST_2148 d97884dd3455057bbfed523106c38785 589 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 298 40.273 T 13-10-2018 IPR033752 MetA family CLOST_2148 d97884dd3455057bbfed523106c38785 589 Gene3D G3DSA:3.40.50.880 1 300 2.7E-115 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 SMART SM01403 8 102 2.6E-58 T 13-10-2018 IPR027486 Ribosomal protein S10 domain CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 Pfam PF00338 Ribosomal protein S10p/S20e 8 102 6.0E-37 T 13-10-2018 IPR027486 Ribosomal protein S10 domain CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 Gene3D G3DSA:3.30.70.600 2 103 1.4E-38 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 30 45 - T 13-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 5 102 9.8E-46 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 4 103 27.373 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 SUPERFAMILY SSF54999 6 103 8.24E-38 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 PRINTS PR00971 Ribosomal protein S10 family signature 62 76 2.1E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 PRINTS PR00971 Ribosomal protein S10 family signature 41 56 2.1E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2199 9b28f04a7f297d0a4024a367244641f8 103 PRINTS PR00971 Ribosomal protein S10 family signature 6 19 2.1E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 Gene3D G3DSA:3.40.50.300 4 245 2.8E-54 T 13-10-2018 CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 Pfam PF00005 ABC transporter 21 175 2.8E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 SUPERFAMILY SSF52540 257 480 1.82E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 Pfam PF00005 ABC transporter 274 428 5.8E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 SUPERFAMILY SSF52540 6 233 1.81E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 Gene3D G3DSA:3.40.50.300 256 502 1.2E-46 T 13-10-2018 CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 SMART SM00382 30 232 9.0E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 SMART SM00382 283 498 2.3E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0686 234247cb9b091f6ef2c763e984e5c1e0 504 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 PRINTS PR00471 Acetate kinase family signature 4 15 2.3E-18 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 PRINTS PR00471 Acetate kinase family signature 295 311 2.3E-18 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 PRINTS PR00471 Acetate kinase family signature 178 199 2.3E-18 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 PRINTS PR00471 Acetate kinase family signature 272 285 2.3E-18 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 SUPERFAMILY SSF53067 148 345 4.17E-50 T 13-10-2018 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 Pfam PF00871 Acetokinase family 3 351 6.3E-62 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 Gene3D G3DSA:3.30.420.40 136 330 4.5E-150 T 13-10-2018 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 Hamap MF_00542 Probable butyrate kinase [buk]. 1 359 155.039 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 4 351 2.4E-158 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 SUPERFAMILY SSF53067 3 171 3.24E-64 T 13-10-2018 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 PIRSF PIRSF036458 1 354 6.2E-156 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0486 45c38c5b0eecf4998f8719aced16e4a3 359 Gene3D G3DSA:3.30.420.40 4 353 4.5E-150 T 13-10-2018 CLOST_2549 aeae61e66d8a9238e5729f63b531c511 398 Pfam PF12704 MacB-like periplasmic core domain 19 234 4.7E-14 T 13-10-2018 IPR025857 MacB-like periplasmic core domain CLOST_2549 aeae61e66d8a9238e5729f63b531c511 398 Pfam PF02687 FtsX-like permease family 298 391 1.3E-8 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CLOST_0013 cfdac948c75f419f66a9099a1fbd75b4 525 SUPERFAMILY SSF55073 378 523 2.28E-33 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0013 cfdac948c75f419f66a9099a1fbd75b4 525 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 372 522 2.9E-34 T 13-10-2018 IPR000160 GGDEF domain CLOST_0013 cfdac948c75f419f66a9099a1fbd75b4 525 Gene3D G3DSA:3.30.70.270 360 524 3.5E-37 T 13-10-2018 CLOST_0013 cfdac948c75f419f66a9099a1fbd75b4 525 SUPERFAMILY SSF48452 88 295 9.48E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0013 cfdac948c75f419f66a9099a1fbd75b4 525 Gene3D G3DSA:1.25.40.10 32 228 1.6E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0013 cfdac948c75f419f66a9099a1fbd75b4 525 Pfam PF00990 Diguanylate cyclase, GGDEF domain 374 520 1.0E-28 T 13-10-2018 IPR000160 GGDEF domain CLOST_0013 cfdac948c75f419f66a9099a1fbd75b4 525 SMART SM00267 362 525 1.9E-30 T 13-10-2018 IPR000160 GGDEF domain CLOST_1914 95427eb3bf4dbc23ad722e076822737d 223 Pfam PF01791 DeoC/LacD family aldolase 7 208 5.7E-24 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CLOST_1914 95427eb3bf4dbc23ad722e076822737d 223 PIRSF PIRSF001357 1 222 5.2E-78 T 13-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CLOST_1914 95427eb3bf4dbc23ad722e076822737d 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 2 217 37.065 T 13-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CLOST_1914 95427eb3bf4dbc23ad722e076822737d 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 4 213 2.1E-93 T 13-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CLOST_1914 95427eb3bf4dbc23ad722e076822737d 223 SUPERFAMILY SSF51569 2 214 1.67E-83 T 13-10-2018 CLOST_1914 95427eb3bf4dbc23ad722e076822737d 223 Gene3D G3DSA:3.20.20.70 1 222 3.2E-96 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1914 95427eb3bf4dbc23ad722e076822737d 223 SMART SM01133 3 215 4.1E-101 T 13-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CLOST_0083 1ca842bfc98f38bd30c62eacd050a17e 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 2.5E-36 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0083 1ca842bfc98f38bd30c62eacd050a17e 315 SUPERFAMILY SSF161098 91 296 4.19E-18 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0083 1ca842bfc98f38bd30c62eacd050a17e 315 Gene3D G3DSA:1.10.3720.10 84 308 4.6E-20 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2563 88059cbcf137f43eeafbec4b3dbeb011 197 Gene3D G3DSA:3.40.630.30 7 159 1.5E-31 T 13-10-2018 CLOST_2563 88059cbcf137f43eeafbec4b3dbeb011 197 Pfam PF13302 Acetyltransferase (GNAT) domain 14 146 3.6E-17 T 13-10-2018 IPR000182 GNAT domain CLOST_2563 88059cbcf137f43eeafbec4b3dbeb011 197 SUPERFAMILY SSF55729 6 148 2.66E-29 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0728 c72b6b5c2fa2e4e6195fc8d5c6b367a0 634 SMART SM00471 443 595 9.1E-5 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0728 c72b6b5c2fa2e4e6195fc8d5c6b367a0 634 Pfam PF13185 GAF domain 279 413 2.9E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 CLOST_0728 c72b6b5c2fa2e4e6195fc8d5c6b367a0 634 Gene3D G3DSA:1.10.3210.10 426 633 9.6E-71 T 13-10-2018 CLOST_0728 c72b6b5c2fa2e4e6195fc8d5c6b367a0 634 Gene3D G3DSA:3.30.450.40 262 425 3.4E-13 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_0728 c72b6b5c2fa2e4e6195fc8d5c6b367a0 634 SUPERFAMILY SSF55781 278 422 4.91E-12 T 13-10-2018 CLOST_0728 c72b6b5c2fa2e4e6195fc8d5c6b367a0 634 Pfam PF01966 HD domain 448 585 2.9E-18 T 13-10-2018 IPR006674 HD domain CLOST_0728 c72b6b5c2fa2e4e6195fc8d5c6b367a0 634 SUPERFAMILY SSF109604 439 623 2.17E-34 T 13-10-2018 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 Gene3D G3DSA:3.30.450.20 389 484 3.6E-20 T 13-10-2018 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 SUPERFAMILY SSF58104 27 347 1.83E-44 T 13-10-2018 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 SUPERFAMILY SSF103190 376 486 9.03E-12 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 Pfam PF02743 Cache domain 370 486 6.7E-13 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 Gene3D G3DSA:1.10.287.950 26 356 1.9E-49 T 13-10-2018 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 112 299 1.1E-26 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 SMART SM00283 74 356 4.0E-15 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 208 237 2.7E-17 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 102 131 2.7E-17 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0340 ad3dd676d7f9df6b91ff4fbed2750366 487 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 179 206 2.7E-17 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_2526 1a9efbf011e0a69c14578fe5ff74c7dd 46 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 10 40 4.0E-6 T 13-10-2018 IPR009303 Protein of unknown function DUF960 CLOST_1837 546c09e9e976da617812df5a54211a0e 410 SUPERFAMILY SSF52374 10 232 4.97E-15 T 13-10-2018 CLOST_1837 546c09e9e976da617812df5a54211a0e 410 Hamap MF_01539 UPF0348 protein . 2 408 35.79 T 13-10-2018 IPR008513 Uncharacterised protein family UPF0348 CLOST_1837 546c09e9e976da617812df5a54211a0e 410 Pfam PF05636 HIGH Nucleotidyl Transferase 1 391 1.0E-133 T 13-10-2018 IPR008513 Uncharacterised protein family UPF0348 CLOST_1837 546c09e9e976da617812df5a54211a0e 410 Gene3D G3DSA:3.40.50.620 2 237 2.4E-35 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1733 e5ea18a24438608c7400d086136eedc3 418 Gene3D G3DSA:2.60.98.20 166 298 3.2E-20 T 13-10-2018 IPR037058 Flagellar hook protein FlgE superfamily CLOST_1733 e5ea18a24438608c7400d086136eedc3 418 Pfam PF00460 Flagella basal body rod protein 5 35 8.9E-11 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CLOST_1733 e5ea18a24438608c7400d086136eedc3 418 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 338 416 4.7E-24 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CLOST_1733 e5ea18a24438608c7400d086136eedc3 418 Pfam PF07559 Flagellar basal body protein FlaE 188 297 6.8E-15 T 13-10-2018 IPR011491 Flagellar hook protein FlgE CLOST_1733 e5ea18a24438608c7400d086136eedc3 418 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 399 2.7E-90 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G CLOST_1733 e5ea18a24438608c7400d086136eedc3 418 SUPERFAMILY SSF117143 92 378 1.44E-71 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like CLOST_2517 afe30b3b743c4fb608cd980308c2b214 549 Pfam PF13408 Recombinase zinc beta ribbon domain 305 370 3.7E-11 T 13-10-2018 IPR025827 Recombinase zinc beta ribbon domain CLOST_2517 afe30b3b743c4fb608cd980308c2b214 549 SMART SM00857 18 167 1.4E-56 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOST_2517 afe30b3b743c4fb608cd980308c2b214 549 Gene3D G3DSA:1.10.10.2600 152 295 7.2E-28 T 13-10-2018 IPR038109 DNA-binding recombinase domain superfamily CLOST_2517 afe30b3b743c4fb608cd980308c2b214 549 Pfam PF00239 Resolvase, N terminal domain 20 165 6.2E-39 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOST_2517 afe30b3b743c4fb608cd980308c2b214 549 ProSitePatterns PS00397 Site-specific recombinases active site. 21 29 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CLOST_2517 afe30b3b743c4fb608cd980308c2b214 549 Gene3D G3DSA:3.40.50.1390 15 149 2.1E-43 T 13-10-2018 CLOST_2517 afe30b3b743c4fb608cd980308c2b214 549 SUPERFAMILY SSF53041 17 165 2.09E-38 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 CLOST_2517 afe30b3b743c4fb608cd980308c2b214 549 Pfam PF07508 Recombinase 191 292 4.6E-23 T 13-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CLOST_1142 fc4aae30b0a87f5b8509d0783493f4f7 339 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 23 88 1.9E-23 T 13-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CLOST_1142 fc4aae30b0a87f5b8509d0783493f4f7 339 Gene3D G3DSA:3.30.930.10 8 339 5.3E-126 T 13-10-2018 CLOST_1142 fc4aae30b0a87f5b8509d0783493f4f7 339 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 339 47.015 T 13-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CLOST_1142 fc4aae30b0a87f5b8509d0783493f4f7 339 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 339 1.5E-106 T 13-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CLOST_1142 fc4aae30b0a87f5b8509d0783493f4f7 339 Pfam PF01409 tRNA synthetases class II core domain (F) 93 339 8.7E-105 T 13-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CLOST_1142 fc4aae30b0a87f5b8509d0783493f4f7 339 SUPERFAMILY SSF55681 93 339 2.74E-85 T 13-10-2018 CLOST_1142 fc4aae30b0a87f5b8509d0783493f4f7 339 SUPERFAMILY SSF46589 16 99 7.85E-20 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 CLOST_0855 15f56f4e8746422b74b168d6d5af5cc8 445 SUPERFAMILY SSF109604 3 422 2.2E-85 T 13-10-2018 CLOST_0855 15f56f4e8746422b74b168d6d5af5cc8 445 Gene3D G3DSA:1.20.1250.30 246 427 9.9E-132 T 13-10-2018 CLOST_0855 15f56f4e8746422b74b168d6d5af5cc8 445 SMART SM00471 49 193 2.8E-11 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0855 15f56f4e8746422b74b168d6d5af5cc8 445 Gene3D G3DSA:1.10.3210.10 5 416 9.9E-132 T 13-10-2018 CLOST_0855 15f56f4e8746422b74b168d6d5af5cc8 445 Pfam PF01966 HD domain 54 160 1.1E-14 T 13-10-2018 IPR006674 HD domain CLOST_1663 5fa1a8cc3cc6d696c97fe8928ff19208 157 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 17 157 1.5E-45 T 13-10-2018 CLOST_1663 5fa1a8cc3cc6d696c97fe8928ff19208 157 Gene3D G3DSA:1.10.10.1590 4 74 3.9E-13 T 13-10-2018 CLOST_1663 5fa1a8cc3cc6d696c97fe8928ff19208 157 Gene3D G3DSA:3.40.30.10 75 157 1.8E-26 T 13-10-2018 CLOST_1663 5fa1a8cc3cc6d696c97fe8928ff19208 157 SUPERFAMILY SSF52833 6 157 9.17E-46 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_1663 5fa1a8cc3cc6d696c97fe8928ff19208 157 PIRSF PIRSF000216 1 157 6.8E-49 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 Gene3D G3DSA:3.30.420.40 132 298 7.5E-128 T 13-10-2018 CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 336 64.063 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 Gene3D G3DSA:3.30.420.40 7 318 7.5E-128 T 13-10-2018 CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 13-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 5.6E-47 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 5.6E-47 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 5.6E-47 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 5.6E-47 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 5.6E-47 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 5.6E-47 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 SUPERFAMILY SSF53067 104 316 2.2E-46 T 13-10-2018 CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 SUPERFAMILY SSF53067 6 125 3.43E-31 T 13-10-2018 CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 Pfam PF00814 Glycoprotease family 27 311 5.9E-104 T 13-10-2018 IPR000905 Gcp-like domain CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 311 5.0E-117 T 13-10-2018 IPR017861 Kae1/TsaD family CLOST_2299 52a845f7db6df7a7d4118a15a2fd8cfd 339 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 318 4.4E-138 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 CLOST_1834 dfe9bcc54ff06605fe6324f9eb693760 532 Pfam PF03961 Flagellar Assembly Protein A 76 524 5.5E-93 T 13-10-2018 IPR005646 Flagellar assembly protein A CLOST_0471 12523529ebf0a0bb7f888cc03be0a2a9 99 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 95 27.164 T 13-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 CLOST_0471 12523529ebf0a0bb7f888cc03be0a2a9 99 Pfam PF04026 SpoVG 1 82 6.1E-37 T 13-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 CLOST_0471 12523529ebf0a0bb7f888cc03be0a2a9 99 Gene3D G3DSA:3.30.1120.40 1 99 2.3E-37 T 13-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 CLOST_0471 12523529ebf0a0bb7f888cc03be0a2a9 99 SUPERFAMILY SSF160537 1 84 1.12E-32 T 13-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 Pfam PF00206 Lyase 6 299 6.9E-70 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 437 38.762 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 Pfam PF14698 Argininosuccinate lyase C-terminal 362 428 1.1E-23 T 13-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 Gene3D G3DSA:1.10.40.30 359 431 2.5E-177 T 13-10-2018 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00145 Argininosuccinate lyase family signature 309 328 1.3E-57 T 13-10-2018 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00145 Argininosuccinate lyase family signature 141 161 1.3E-57 T 13-10-2018 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00145 Argininosuccinate lyase family signature 274 290 1.3E-57 T 13-10-2018 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 1.3E-57 T 13-10-2018 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00145 Argininosuccinate lyase family signature 192 208 1.3E-57 T 13-10-2018 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00145 Argininosuccinate lyase family signature 230 254 1.3E-57 T 13-10-2018 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 Gene3D G3DSA:1.10.275.10 25 228 2.5E-177 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 430 7.5E-171 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 Gene3D G3DSA:1.20.200.10 119 358 2.5E-177 T 13-10-2018 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 ProSitePatterns PS00163 Fumarate lyases signature. 274 283 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 SUPERFAMILY SSF48557 3 430 6.91E-130 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 1.6E-23 T 13-10-2018 IPR000362 Fumarate lyase family CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00149 Fumarate lyase superfamily signature 230 257 1.6E-23 T 13-10-2018 IPR000362 Fumarate lyase family CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 1.6E-23 T 13-10-2018 IPR000362 Fumarate lyase family CLOST_0140 173f5efd03c0d5c0b90b553422d02d45 438 PRINTS PR00149 Fumarate lyase superfamily signature 274 290 1.6E-23 T 13-10-2018 IPR000362 Fumarate lyase family CLOST_1744 e6ee80c7720e81eebbe416a5456e4681 130 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 5 127 4.4E-27 T 13-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CLOST_1744 e6ee80c7720e81eebbe416a5456e4681 130 PIRSF PIRSF002889 1 129 5.9E-30 T 13-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CLOST_0777 7400ac3b39fc58f8c83a3e60292c37a4 409 Pfam PF13416 Bacterial extracellular solute-binding protein 65 360 2.7E-29 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein CLOST_0777 7400ac3b39fc58f8c83a3e60292c37a4 409 Gene3D G3DSA:3.40.190.10 163 307 1.7E-21 T 13-10-2018 CLOST_0777 7400ac3b39fc58f8c83a3e60292c37a4 409 Gene3D G3DSA:3.40.190.10 68 365 1.7E-21 T 13-10-2018 CLOST_0777 7400ac3b39fc58f8c83a3e60292c37a4 409 SUPERFAMILY SSF53850 43 369 4.09E-37 T 13-10-2018 CLOST_0777 7400ac3b39fc58f8c83a3e60292c37a4 409 PIRSF PIRSF029172 1 407 3.2E-143 T 13-10-2018 IPR027020 Protein ynjB CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 SMART SM00904 181 309 8.1E-50 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 Gene3D G3DSA:3.40.50.620 3 183 8.9E-51 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 Pfam PF01687 Riboflavin kinase 182 307 4.8E-36 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 SUPERFAMILY SSF52374 14 173 1.27E-30 T 13-10-2018 CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 307 3.1E-76 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 Pfam PF06574 FAD synthetase 12 164 1.8E-43 T 13-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 PIRSF PIRSF004491 1 310 3.9E-102 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 17 57 4.1E-7 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 Gene3D G3DSA:2.40.30.30 184 310 3.9E-41 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 CLOST_1686 ec29d0d0324d4f09c625e6d75b8b1777 310 SUPERFAMILY SSF82114 172 307 4.58E-43 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 CLOST_0843 97a231d9fff57bf745a77db17f6e214f 168 SUPERFAMILY SSF103642 145 165 5.07E-8 T 13-10-2018 CLOST_0843 97a231d9fff57bf745a77db17f6e214f 168 Gene3D G3DSA:3.10.450.50 95 166 2.3E-10 T 13-10-2018 CLOST_0843 97a231d9fff57bf745a77db17f6e214f 168 Pfam PF02810 SEC-C motif 147 165 7.5E-10 T 13-10-2018 IPR004027 SEC-C motif CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 SMART SM00533 8 310 5.6E-24 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 SUPERFAMILY SSF48334 20 284 4.58E-21 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 SMART SM00534 322 507 1.5E-68 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 PIRSF PIRSF005814 1 581 2.6E-196 T 13-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 PIRSF PIRSF005814 552 653 0.37 T 13-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 Gene3D G3DSA:3.40.50.300 288 584 3.3E-79 T 13-10-2018 CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 Pfam PF00488 MutS domain V 325 506 7.4E-37 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 SUPERFAMILY SSF52540 288 507 8.26E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 Gene3D G3DSA:1.10.1420.10 33 276 3.5E-8 T 13-10-2018 CLOST_0175 8bbaf7b7a378bc1e33fb83c682bf4671 653 Gene3D G3DSA:1.10.1420.10 110 222 3.5E-8 T 13-10-2018 CLOST_0538 843c2eb693aaf96992c80bf5bcf9b2a7 321 SUPERFAMILY SSF53822 45 313 1.57E-43 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_0538 843c2eb693aaf96992c80bf5bcf9b2a7 321 Pfam PF13407 Periplasmic binding protein domain 47 302 3.5E-42 T 13-10-2018 IPR025997 Periplasmic binding protein CLOST_0538 843c2eb693aaf96992c80bf5bcf9b2a7 321 Gene3D G3DSA:3.40.50.2300 148 283 6.1E-56 T 13-10-2018 CLOST_0538 843c2eb693aaf96992c80bf5bcf9b2a7 321 Gene3D G3DSA:3.40.50.2300 57 306 6.1E-56 T 13-10-2018 CLOST_2141 1257367c54ac3effc2c58997565f17c1 80 SMART SM00966 8 51 1.4E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CLOST_2141 1257367c54ac3effc2c58997565f17c1 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 47 8.1E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CLOST_2141 1257367c54ac3effc2c58997565f17c1 80 Gene3D G3DSA:2.10.260.10 1 52 1.3E-21 T 13-10-2018 CLOST_2141 1257367c54ac3effc2c58997565f17c1 80 SUPERFAMILY SSF89447 2 53 3.01E-15 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily CLOST_2141 1257367c54ac3effc2c58997565f17c1 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.5E-10 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CLOST_0664 93d128e2603a9a36b39f9b48de6a5d92 390 PIRSF PIRSF001238 1 390 3.6E-161 T 13-10-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 CLOST_0664 93d128e2603a9a36b39f9b48de6a5d92 390 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 3 389 3.7E-167 T 13-10-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 CLOST_0664 93d128e2603a9a36b39f9b48de6a5d92 390 Pfam PF01979 Amidohydrolase family 53 375 3.2E-21 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CLOST_0664 93d128e2603a9a36b39f9b48de6a5d92 390 SUPERFAMILY SSF51556 56 346 5.38E-73 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_0664 93d128e2603a9a36b39f9b48de6a5d92 390 Gene3D G3DSA:2.30.40.10 4 389 4.7E-153 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0664 93d128e2603a9a36b39f9b48de6a5d92 390 Gene3D G3DSA:3.20.20.140 57 342 4.7E-153 T 13-10-2018 CLOST_0664 93d128e2603a9a36b39f9b48de6a5d92 390 SUPERFAMILY SSF51338 1 388 5.22E-20 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0653 84a12cbf4f0afdd95ff337824cc7a677 311 Gene3D G3DSA:3.30.457.10 77 158 1.4E-10 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0653 84a12cbf4f0afdd95ff337824cc7a677 311 Pfam PF07833 Copper amine oxidase N-terminal domain 74 165 8.8E-17 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0653 84a12cbf4f0afdd95ff337824cc7a677 311 SUPERFAMILY SSF55383 77 160 1.07E-13 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0699 07b583fb7b564a177d2a7a2e136b5c2c 453 Gene3D G3DSA:3.80.30.20 180 394 1.1E-17 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_0699 07b583fb7b564a177d2a7a2e136b5c2c 453 Pfam PF02310 B12 binding domain 37 131 4.6E-11 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0699 07b583fb7b564a177d2a7a2e136b5c2c 453 SMART SM00729 182 387 1.3E-23 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0699 07b583fb7b564a177d2a7a2e136b5c2c 453 Pfam PF04055 Radical SAM superfamily 187 346 3.2E-14 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0699 07b583fb7b564a177d2a7a2e136b5c2c 453 SUPERFAMILY SSF102114 156 403 1.1E-34 T 13-10-2018 CLOST_0743 2f61d74fd10858142ea7ceecafb4011c 242 Pfam PF07722 Peptidase C26 4 220 2.2E-64 T 13-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CLOST_0743 2f61d74fd10858142ea7ceecafb4011c 242 SUPERFAMILY SSF52317 29 239 2.62E-37 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0743 2f61d74fd10858142ea7ceecafb4011c 242 Gene3D G3DSA:3.40.50.880 1 242 6.0E-75 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_1832 16d7f607459606f2571be624ecca58c3 591 SMART SM00267 158 325 2.2E-54 T 13-10-2018 IPR000160 GGDEF domain CLOST_1832 16d7f607459606f2571be624ecca58c3 591 Pfam PF00563 EAL domain 342 572 3.8E-64 T 13-10-2018 IPR001633 EAL domain CLOST_1832 16d7f607459606f2571be624ecca58c3 591 Gene3D G3DSA:3.20.20.450 339 587 1.4E-84 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_1832 16d7f607459606f2571be624ecca58c3 591 Pfam PF00990 Diguanylate cyclase, GGDEF domain 169 321 3.6E-43 T 13-10-2018 IPR000160 GGDEF domain CLOST_1832 16d7f607459606f2571be624ecca58c3 591 SUPERFAMILY SSF55073 174 326 2.88E-48 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_1832 16d7f607459606f2571be624ecca58c3 591 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 165 324 9.4E-42 T 13-10-2018 IPR000160 GGDEF domain CLOST_1832 16d7f607459606f2571be624ecca58c3 591 Gene3D G3DSA:3.30.70.270 163 338 3.2E-57 T 13-10-2018 CLOST_1832 16d7f607459606f2571be624ecca58c3 591 SMART SM00052 335 577 1.8E-90 T 13-10-2018 IPR001633 EAL domain CLOST_1832 16d7f607459606f2571be624ecca58c3 591 SUPERFAMILY SSF141868 341 582 1.09E-77 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0713 50f1079cb632b4e5bdf2a41ca96b555d 460 Pfam PF01523 Putative modulator of DNA gyrase 21 313 2.2E-63 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CLOST_0713 50f1079cb632b4e5bdf2a41ca96b555d 460 PIRSF PIRSF004919 1 460 4.7E-122 T 13-10-2018 IPR025502 TldD CLOST_0713 50f1079cb632b4e5bdf2a41ca96b555d 460 Gene3D G3DSA:3.30.2290.10 2 221 1.1E-18 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal CLOST_0713 50f1079cb632b4e5bdf2a41ca96b555d 460 SUPERFAMILY SSF111283 4 459 4.32E-119 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 CLOST_1512 1e6f2144ce76c13a8cae686a108f60a4 360 Pfam PF04865 Baseplate J-like protein 66 320 1.7E-50 T 13-10-2018 IPR006949 Baseplate protein J-like CLOST_1541 f72f80c8b200df4c775eae6653516352 138 Hamap MF_00984 Single-stranded DNA-binding protein. 1 107 31.951 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CLOST_1541 f72f80c8b200df4c775eae6653516352 138 Pfam PF00436 Single-strand binding protein family 1 103 1.9E-34 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CLOST_1541 f72f80c8b200df4c775eae6653516352 138 PIRSF PIRSF002070 1 130 5.3E-37 T 13-10-2018 CLOST_1541 f72f80c8b200df4c775eae6653516352 138 Gene3D G3DSA:2.40.50.140 1 113 6.8E-43 T 13-10-2018 CLOST_1541 f72f80c8b200df4c775eae6653516352 138 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 114 4.9E-36 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CLOST_1541 f72f80c8b200df4c775eae6653516352 138 SUPERFAMILY SSF50249 1 138 2.36E-43 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2045 bb960fce3ccb9939850f6306616c2b39 216 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 11 215 2.1E-64 T 13-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CLOST_2045 bb960fce3ccb9939850f6306616c2b39 216 Pfam PF03006 Haemolysin-III related 9 209 1.6E-47 T 13-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 243 1.3E-57 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CLOST_1464 91b165454a63349f40650eea5223ed5d 258 Pfam PF03705 CheR methyltransferase, all-alpha domain 3 53 1.7E-12 T 13-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CLOST_1464 91b165454a63349f40650eea5223ed5d 258 PRINTS PR00996 Glutamate methyltransferase family signature 97 117 4.9E-36 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 PRINTS PR00996 Glutamate methyltransferase family signature 215 238 4.9E-36 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 PRINTS PR00996 Glutamate methyltransferase family signature 129 145 4.9E-36 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 PRINTS PR00996 Glutamate methyltransferase family signature 23 36 4.9E-36 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 4.9E-36 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 PRINTS PR00996 Glutamate methyltransferase family signature 196 210 4.9E-36 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 Gene3D G3DSA:3.40.50.150 66 257 1.4E-66 T 13-10-2018 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 SUPERFAMILY SSF47757 3 66 1.7E-10 T 13-10-2018 CLOST_1464 91b165454a63349f40650eea5223ed5d 258 SUPERFAMILY SSF53335 67 240 2.71E-46 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1464 91b165454a63349f40650eea5223ed5d 258 SMART SM00138 1 255 2.0E-84 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CLOST_2087 c17e3c50c7b558ebf411b848958118ae 330 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 6 303 7.3E-86 T 13-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CLOST_2087 c17e3c50c7b558ebf411b848958118ae 330 SUPERFAMILY SSF55681 2 237 1.56E-70 T 13-10-2018 CLOST_2087 c17e3c50c7b558ebf411b848958118ae 330 Gene3D G3DSA:3.30.390.50 238 325 2.8E-18 T 13-10-2018 CLOST_2087 c17e3c50c7b558ebf411b848958118ae 330 Gene3D G3DSA:3.30.930.10 2 237 2.3E-73 T 13-10-2018 CLOST_2087 c17e3c50c7b558ebf411b848958118ae 330 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 242 323 8.5E-19 T 13-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CLOST_2087 c17e3c50c7b558ebf411b848958118ae 330 Pfam PF03099 Biotin/lipoate A/B protein ligase family 45 148 7.5E-6 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CLOST_2087 c17e3c50c7b558ebf411b848958118ae 330 SUPERFAMILY SSF82649 240 324 9.94E-17 T 13-10-2018 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 PRINTS PR00702 Acriflavin resistance protein family signature 374 397 2.0E-8 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 PRINTS PR00702 Acriflavin resistance protein family signature 299 323 2.0E-8 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 PRINTS PR00702 Acriflavin resistance protein family signature 246 269 2.0E-8 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 130 397 1.9E-98 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 SUPERFAMILY SSF82866 142 398 3.27E-37 T 13-10-2018 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 412 37.752 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 Gene3D G3DSA:3.30.1360.200 82 222 1.0E-32 T 13-10-2018 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 158 390 4.3E-71 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 Gene3D G3DSA:1.20.1640.10 241 400 2.1E-7 T 13-10-2018 CLOST_1310 632055744a85d965ffc5d59d63fcbc66 414 Pfam PF02355 Protein export membrane protein 229 398 2.6E-18 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 116 3.1E-23 T 13-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 PIRSF PIRSF000804 1 363 2.9E-105 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 SUPERFAMILY SSF55979 245 363 3.98E-34 T 13-10-2018 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 SMART SM00480 17 359 4.3E-99 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 Gene3D G3DSA:3.70.10.10 137 361 9.2E-110 T 13-10-2018 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 362 9.5E-33 T 13-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 240 2.0E-24 T 13-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 362 4.6E-88 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 SUPERFAMILY SSF55979 2 116 1.57E-22 T 13-10-2018 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 Gene3D G3DSA:3.10.150.10 2 241 9.2E-110 T 13-10-2018 CLOST_0002 3f47f3b587e04fb4ee595180c7ab9767 363 SUPERFAMILY SSF55979 128 243 1.59E-22 T 13-10-2018 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 PRINTS PR00125 ATP synthase delta subunit signature 5 24 5.5E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 PRINTS PR00125 ATP synthase delta subunit signature 85 99 5.5E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 PRINTS PR00125 ATP synthase delta subunit signature 150 168 5.5E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 PRINTS PR00125 ATP synthase delta subunit signature 135 150 5.5E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 PRINTS PR00125 ATP synthase delta subunit signature 74 85 5.5E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 SUPERFAMILY SSF47928 4 106 2.48E-23 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 Pfam PF00213 ATP synthase delta (OSCP) subunit 5 174 1.7E-48 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 5 173 1.9E-45 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 177 19.998 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2119 5ff07acea63d54da83cff27e61653995 180 Gene3D G3DSA:1.10.520.20 5 98 1.6E-14 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2126 d10a1081ead59acc8f2afafe600e36da 345 ProSitePatterns PS01348 MraY family signature 2. 150 161 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_2126 d10a1081ead59acc8f2afafe600e36da 345 Pfam PF00953 Glycosyl transferase family 4 72 229 1.1E-43 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 SUPERFAMILY SSF53067 164 343 1.57E-42 T 13-10-2018 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 6 13 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 299 313 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 Gene3D G3DSA:3.90.640.10 199 277 8.2E-79 T 13-10-2018 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 Gene3D G3DSA:3.30.420.40 2 75 3.0E-20 T 13-10-2018 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 SUPERFAMILY SSF100920 349 508 1.24E-33 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 PRINTS PR00301 70kDa heat shock protein signature 173 183 9.9E-42 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 PRINTS PR00301 70kDa heat shock protein signature 327 347 9.9E-42 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 PRINTS PR00301 70kDa heat shock protein signature 30 42 9.9E-42 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 PRINTS PR00301 70kDa heat shock protein signature 296 312 9.9E-42 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 PRINTS PR00301 70kDa heat shock protein signature 352 371 9.9E-42 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 PRINTS PR00301 70kDa heat shock protein signature 437 453 9.9E-42 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 PRINTS PR00301 70kDa heat shock protein signature 2 15 9.9E-42 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 PRINTS PR00301 70kDa heat shock protein signature 113 133 9.9E-42 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 Gene3D G3DSA:3.30.420.40 159 324 8.2E-79 T 13-10-2018 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 Gene3D G3DSA:3.30.420.40 94 338 8.2E-79 T 13-10-2018 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 167 180 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 Pfam PF00012 Hsp70 protein 4 74 4.9E-17 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 Pfam PF00012 Hsp70 protein 79 541 1.8E-116 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 SUPERFAMILY SSF53067 2 157 1.6E-49 T 13-10-2018 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 Gene3D G3DSA:2.60.34.10 340 521 1.3E-41 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 CLOST_0384 93b8d2fd1bcce70657881a29c88c9b9c 562 Gene3D G3DSA:3.30.30.30 78 93 8.2E-79 T 13-10-2018 CLOST_2358 66a7ba848645b40d868c294ed7f7808e 154 Pfam PF06695 Putative small multi-drug export protein 24 144 3.8E-39 T 13-10-2018 IPR009577 Putative small multi-drug export CLOST_0562 c7cd551206291003882e233375e27088 219 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 10 43 1.3E-9 T 13-10-2018 IPR023833 Signal peptide, camelysin CLOST_0562 c7cd551206291003882e233375e27088 219 Pfam PF12389 Camelysin metallo-endopeptidase 2 63 2.9E-12 T 13-10-2018 IPR022121 Peptidase M73, camelysin CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 358 38.05 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 Gene3D G3DSA:3.30.1330.20 222 331 3.8E-34 T 13-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 SUPERFAMILY SSF55307 205 320 1.3E-36 T 13-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 Gene3D G3DSA:3.40.50.1440 4 220 6.9E-86 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 SUPERFAMILY SSF52490 14 209 3.4E-72 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 PRINTS PR00423 Cell division protein FtsZ signature 127 148 7.0E-48 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 PRINTS PR00423 Cell division protein FtsZ signature 190 212 7.0E-48 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 PRINTS PR00423 Cell division protein FtsZ signature 99 119 7.0E-48 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 PRINTS PR00423 Cell division protein FtsZ signature 213 234 7.0E-48 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 ProSitePatterns PS01135 FtsZ protein signature 2. 98 119 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 SMART SM00864 14 206 3.9E-115 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 174 4.0E-44 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 SMART SM00865 208 327 1.4E-45 T 13-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 5 328 9.1E-126 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 CLOST_1890 775c6b9500b365de68cf5fbc6c72429a 369 Pfam PF12327 FtsZ family, C-terminal domain 223 319 5.0E-28 T 13-10-2018 IPR024757 Cell division protein FtsZ, C-terminal CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 Hamap MF_01491 Ribonuclease J [rnj]. 3 554 47.85 T 13-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 Pfam PF00753 Metallo-beta-lactamase superfamily 21 163 4.7E-15 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 Gene3D G3DSA:3.40.50.10710 206 364 1.1E-193 T 13-10-2018 CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 354 413 1.6E-10 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 Gene3D G3DSA:3.60.15.10 9 435 1.1E-193 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 8 552 4.6E-208 T 13-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 SMART SM00849 20 212 2.3E-24 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 SUPERFAMILY SSF56281 8 423 3.01E-102 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 Gene3D G3DSA:3.10.20.580 448 554 2.0E-40 T 13-10-2018 CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 363 391 - T 13-10-2018 IPR001587 Ribonuclease J, conserved site CLOST_1482 8933cb5039e344109d09a2f3f6b97c04 554 PIRSF PIRSF004803 1 554 1.7E-251 T 13-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Gene3D G3DSA:3.90.1440.10 224 345 2.8E-183 T 13-10-2018 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 ProSitePatterns PS01312 SecA family signature. 477 492 - T 13-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 SMART SM00958 223 335 7.4E-67 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Pfam PF01043 SecA preprotein cross-linking domain 227 335 2.9E-42 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 835 19.984 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 SMART SM00957 1 379 1.3E-284 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 23 821 0.0 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Gene3D G3DSA:3.40.50.300 394 624 6.4E-92 T 13-10-2018 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 PRINTS PR00906 SecA protein signature 58 82 3.5E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 PRINTS PR00906 SecA protein signature 353 370 3.5E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 PRINTS PR00906 SecA protein signature 96 110 3.5E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 PRINTS PR00906 SecA protein signature 316 338 3.5E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 PRINTS PR00906 SecA protein signature 165 185 3.5E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 PRINTS PR00906 SecA protein signature 390 403 3.5E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 PRINTS PR00906 SecA protein signature 112 122 3.5E-71 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Gene3D G3DSA:1.10.3060.10 626 836 7.5E-74 T 13-10-2018 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Pfam PF07516 SecA Wing and Scaffold domain 622 830 2.0E-68 T 13-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 SUPERFAMILY SSF81767 222 345 2.35E-46 T 13-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Pfam PF02810 SEC-C motif 876 894 8.9E-10 T 13-10-2018 IPR004027 SEC-C motif CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Pfam PF07517 SecA DEAD-like domain 9 379 2.0E-130 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 Gene3D G3DSA:3.40.50.300 17 392 2.8E-183 T 13-10-2018 CLOST_2312 ed35636692a4304d62ef2819a82db802 897 SUPERFAMILY SSF52540 394 623 5.47E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2312 ed35636692a4304d62ef2819a82db802 897 SUPERFAMILY SSF52540 8 392 2.42E-84 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2312 ed35636692a4304d62ef2819a82db802 897 SUPERFAMILY SSF81886 625 884 1.18E-79 T 13-10-2018 IPR036266 SecA, Wing/Scaffold superfamily CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 SUPERFAMILY SSF58104 413 742 3.14E-63 T 13-10-2018 CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 Gene3D G3DSA:1.10.287.950 441 742 7.6E-61 T 13-10-2018 CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 Gene3D G3DSA:1.20.1480.50 344 440 3.8E-9 T 13-10-2018 CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 SMART SM00304 383 438 9.5E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 SUPERFAMILY SSF103190 162 252 2.43E-5 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 534 677 2.0E-34 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 Pfam PF17203 Single cache domain 3 256 358 1.9E-10 T 13-10-2018 IPR033463 Single cache domain 3 CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 SUPERFAMILY SSF103190 242 356 1.26E-10 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0407 b84baeea677ba9bfd08e7a0dc72aa3fa 743 SMART SM00283 467 742 2.3E-53 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_1321 ce567bfca413e17033f46e85d96c8fab 668 Gene3D G3DSA:3.40.50.1820 416 668 1.9E-67 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold CLOST_1321 ce567bfca413e17033f46e85d96c8fab 668 SUPERFAMILY SSF53474 415 668 5.36E-63 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold CLOST_1321 ce567bfca413e17033f46e85d96c8fab 668 Pfam PF00326 Prolyl oligopeptidase family 461 668 1.1E-52 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CLOST_1321 ce567bfca413e17033f46e85d96c8fab 668 SUPERFAMILY SSF82171 14 392 3.92E-18 T 13-10-2018 CLOST_1124 2b1d1795a81c20492bf8235cc64c1225 215 Gene3D G3DSA:3.40.1080.10 1 211 2.8E-94 T 13-10-2018 CLOST_1124 2b1d1795a81c20492bf8235cc64c1225 215 SUPERFAMILY SSF100950 3 214 1.41E-71 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_1124 2b1d1795a81c20492bf8235cc64c1225 215 SMART SM00882 4 199 3.1E-70 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 CLOST_1124 2b1d1795a81c20492bf8235cc64c1225 215 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 2 206 4.4E-96 T 13-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CLOST_1124 2b1d1795a81c20492bf8235cc64c1225 215 Pfam PF01144 Coenzyme A transferase 4 199 3.9E-40 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 CLOST_1124 2b1d1795a81c20492bf8235cc64c1225 215 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 42 50 - T 13-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 Pfam PF00800 Prephenate dehydratase 98 275 7.4E-59 T 13-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 SUPERFAMILY SSF53850 97 277 2.06E-56 T 13-10-2018 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 Gene3D G3DSA:3.40.190.10 182 263 1.3E-26 T 13-10-2018 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 Pfam PF01817 Chorismate mutase type II 11 85 1.5E-15 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 SUPERFAMILY SSF55021 269 363 2.29E-23 T 13-10-2018 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 250 272 - T 13-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 Gene3D G3DSA:3.30.70.260 279 366 3.7E-27 T 13-10-2018 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 Gene3D G3DSA:3.40.190.10 91 181 1.5E-25 T 13-10-2018 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 PIRSF PIRSF001500 2 367 2.3E-101 T 13-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 Gene3D G3DSA:1.20.59.10 1 86 1.4E-17 T 13-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 TIGRFAM TIGR01805 CM_mono_grmpos: chorismate mutase 5 84 2.3E-21 T 13-10-2018 IPR011279 Chorismate mutase, Gram-positive CLOST_0652 527737c96669c2cec6360eebb08096bc 369 SUPERFAMILY SSF48600 4 86 9.34E-15 T 13-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CLOST_0652 527737c96669c2cec6360eebb08096bc 369 SMART SM00830 8 87 1.4E-14 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 Gene3D G3DSA:3.40.50.920 489 620 1.5E-28 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 ProSitePatterns PS00801 Transketolase signature 1. 30 49 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 616 8.8E-229 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 4 618 41.753 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 Pfam PF02780 Transketolase, C-terminal domain 489 609 2.6E-19 T 13-10-2018 IPR033248 Transketolase, C-terminal domain CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 SUPERFAMILY SSF52922 489 617 1.57E-21 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 Gene3D G3DSA:3.40.50.970 311 485 1.9E-59 T 13-10-2018 CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 Pfam PF02779 Transketolase, pyrimidine binding domain 313 474 5.8E-34 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 280 1.1E-116 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 SUPERFAMILY SSF52518 2 376 7.59E-69 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 SMART SM00861 314 478 5.2E-53 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CLOST_1343 5b2f93a07a0663b00a249135147a21bc 627 ProSitePatterns PS00802 Transketolase signature 2. 420 436 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 SUPERFAMILY SSF52096 3 263 1.54E-91 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 35 46 8.8E-47 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 144 153 8.8E-47 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 60 78 8.8E-47 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 81 97 8.8E-47 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 129 8.8E-47 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 100 113 8.8E-47 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 263 39.695 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 3 95 3.3E-51 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 264 9.8E-123 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 CLOST_0892 7ec91545e8a87056a69c142eb0bac224 265 Gene3D G3DSA:3.90.226.10 1 265 9.6E-105 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 403 618 4.2E-40 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:3.30.420.10 406 539 1.6E-42 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:2.40.50.140 212 306 3.4E-25 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1417 360.173 T 13-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:3.20.20.140 540 786 2.0E-50 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:3.20.20.140 315 405 1.5E-21 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:3.30.1900.20 953 1075 1.0E-55 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:1.10.150.870 1268 1403 8.4E-42 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 804 1217 1.1E-90 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 SMART SM00481 321 388 7.9E-22 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 SUPERFAMILY SSF53098 405 858 5.69E-100 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:1.10.150.700 1076 1176 5.1E-31 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:1.10.150.700 1215 1266 1.0E-14 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Pfam PF02811 PHP domain 322 677 4.9E-47 T 13-10-2018 IPR004013 PHP domain GO:0003824 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Gene3D G3DSA:1.10.100.20 975 1022 1.0E-55 T 13-10-2018 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Pfam PF14579 Helix-hairpin-helix motif 1329 1411 1.8E-9 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 SUPERFAMILY SSF50249 231 300 1.11E-7 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 Pfam PF00929 Exonuclease 407 561 1.7E-34 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 225 1417 0.0 T 13-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1695 f7ae65359d6d1c823d93c1cd1560b04a 1417 SMART SM00479 405 570 1.3E-44 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CLOST_0507 73ca968bb027db2462df49234ab62502 654 Gene3D G3DSA:3.40.50.300 412 593 9.1E-53 T 13-10-2018 CLOST_0507 73ca968bb027db2462df49234ab62502 654 SUPERFAMILY SSF52540 34 577 2.93E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0507 73ca968bb027db2462df49234ab62502 654 Gene3D G3DSA:3.40.50.300 264 411 2.3E-52 T 13-10-2018 CLOST_0507 73ca968bb027db2462df49234ab62502 654 Pfam PF12344 Ultra-violet resistance protein B 549 591 8.5E-21 T 13-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CLOST_0507 73ca968bb027db2462df49234ab62502 654 Gene3D G3DSA:4.10.860.10 604 654 5.6E-8 T 13-10-2018 CLOST_0507 73ca968bb027db2462df49234ab62502 654 Pfam PF00271 Helicase conserved C-terminal domain 435 542 9.9E-19 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0507 73ca968bb027db2462df49234ab62502 654 Gene3D G3DSA:3.40.50.300 1 232 3.8E-82 T 13-10-2018 CLOST_0507 73ca968bb027db2462df49234ab62502 654 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 2 650 0.0 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 CLOST_0507 73ca968bb027db2462df49234ab62502 654 SUPERFAMILY SSF46600 613 652 1.57E-9 T 13-10-2018 IPR036876 UVR domain superfamily CLOST_0507 73ca968bb027db2462df49234ab62502 654 Hamap MF_00204 UvrABC system protein B [uvrB]. 1 653 43.492 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 CLOST_0507 73ca968bb027db2462df49234ab62502 654 Pfam PF04851 Type III restriction enzyme, res subunit 13 136 2.4E-12 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CLOST_0507 73ca968bb027db2462df49234ab62502 654 Pfam PF02151 UvrB/uvrC motif 618 652 1.5E-8 T 13-10-2018 IPR001943 UVR domain GO:0005515 CLOST_0507 73ca968bb027db2462df49234ab62502 654 SMART SM00487 7 423 2.9E-29 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_0507 73ca968bb027db2462df49234ab62502 654 SUPERFAMILY SSF52540 3 412 1.3E-137 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0507 73ca968bb027db2462df49234ab62502 654 SMART SM00490 457 543 1.3E-20 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0232 2055b819a45039ea8fd303547a9ec05d 519 SUPERFAMILY SSF56317 226 494 2.09E-57 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily CLOST_0232 2055b819a45039ea8fd303547a9ec05d 519 Gene3D G3DSA:3.60.110.10 226 512 2.5E-56 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily CLOST_0232 2055b819a45039ea8fd303547a9ec05d 519 Gene3D G3DSA:3.40.630.30 7 224 6.1E-57 T 13-10-2018 CLOST_0232 2055b819a45039ea8fd303547a9ec05d 519 Pfam PF00583 Acetyltransferase (GNAT) family 27 148 1.4E-10 T 13-10-2018 IPR000182 GNAT domain CLOST_0232 2055b819a45039ea8fd303547a9ec05d 519 Pfam PF00795 Carbon-nitrogen hydrolase 241 486 3.9E-28 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 CLOST_0232 2055b819a45039ea8fd303547a9ec05d 519 SUPERFAMILY SSF55729 15 143 5.49E-17 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 Gene3D G3DSA:1.10.10.1600 429 506 2.2E-26 T 13-10-2018 CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 Pfam PF14579 Helix-hairpin-helix motif 803 891 1.1E-24 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 Pfam PF02811 PHP domain 7 178 3.1E-54 T 13-10-2018 IPR004013 PHP domain GO:0003824 CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 Gene3D G3DSA:3.20.20.140 1 275 1.5E-114 T 13-10-2018 CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 296 716 1.1E-173 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 SMART SM00481 6 73 3.0E-32 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 Pfam PF01336 OB-fold nucleic acid binding domain 994 1071 1.3E-7 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1031 0.0 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 SUPERFAMILY SSF89550 4 268 5.89E-40 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CLOST_1649 28cd2c21d80228349dff789a9307158f 1150 Gene3D G3DSA:1.10.150.870 782 880 1.3E-6 T 13-10-2018 CLOST_0417 24863fa522fcfdfa972d77ff226a0204 383 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 347 3.2E-133 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CLOST_0417 24863fa522fcfdfa972d77ff226a0204 383 Gene3D G3DSA:3.40.718.10 1 372 1.2E-141 T 13-10-2018 CLOST_0417 24863fa522fcfdfa972d77ff226a0204 383 SMART SM01329 5 366 8.1E-188 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CLOST_0417 24863fa522fcfdfa972d77ff226a0204 383 SUPERFAMILY SSF53659 2 343 2.11E-116 T 13-10-2018 CLOST_0417 24863fa522fcfdfa972d77ff226a0204 383 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CLOST_0417 24863fa522fcfdfa972d77ff226a0204 383 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 4 370 49.153 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CLOST_0417 24863fa522fcfdfa972d77ff226a0204 383 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 340 3.8E-148 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CLOST_0919 449526df4f76db5ee30827b3a0fb7cd1 300 Pfam PF00753 Metallo-beta-lactamase superfamily 25 208 2.3E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0919 449526df4f76db5ee30827b3a0fb7cd1 300 SMART SM00849 15 208 2.0E-15 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0919 449526df4f76db5ee30827b3a0fb7cd1 300 Gene3D G3DSA:3.60.15.10 1 230 2.0E-28 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_0919 449526df4f76db5ee30827b3a0fb7cd1 300 SUPERFAMILY SSF56281 26 261 3.22E-31 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1462 a8da185d078492e022ba62019866547f 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 13-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CLOST_1462 a8da185d078492e022ba62019866547f 53 Pfam PF00301 Rubredoxin 3 49 2.3E-26 T 13-10-2018 IPR024935 Rubredoxin domain GO:0005506 CLOST_1462 a8da185d078492e022ba62019866547f 53 PRINTS PR00163 Rubredoxin signature 33 49 1.7E-13 T 13-10-2018 IPR024935 Rubredoxin domain GO:0005506 CLOST_1462 a8da185d078492e022ba62019866547f 53 PRINTS PR00163 Rubredoxin signature 3 19 1.7E-13 T 13-10-2018 IPR024935 Rubredoxin domain GO:0005506 CLOST_1462 a8da185d078492e022ba62019866547f 53 PIRSF PIRSF000071 1 53 6.2E-29 T 13-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 CLOST_1462 a8da185d078492e022ba62019866547f 53 SUPERFAMILY SSF57802 1 51 1.65E-24 T 13-10-2018 CLOST_1462 a8da185d078492e022ba62019866547f 53 Gene3D G3DSA:2.20.28.10 1 52 2.6E-29 T 13-10-2018 CLOST_0490 294f35d07129dd8a1424fd8912ba6f95 72 Gene3D G3DSA:3.30.70.20 1 38 7.2E-8 T 13-10-2018 CLOST_0490 294f35d07129dd8a1424fd8912ba6f95 72 Gene3D G3DSA:3.30.70.3270 39 72 5.9E-6 T 13-10-2018 CLOST_0490 294f35d07129dd8a1424fd8912ba6f95 72 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0490 294f35d07129dd8a1424fd8912ba6f95 72 Pfam PF12838 4Fe-4S dicluster domain 12 62 1.4E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0490 294f35d07129dd8a1424fd8912ba6f95 72 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0490 294f35d07129dd8a1424fd8912ba6f95 72 SUPERFAMILY SSF54862 3 69 3.22E-17 T 13-10-2018 CLOST_0722 6c6a640d5c3fbd92c3a1e43ba4f6f7e7 251 Gene3D G3DSA:3.30.460.10 14 163 8.0E-49 T 13-10-2018 CLOST_0722 6c6a640d5c3fbd92c3a1e43ba4f6f7e7 251 SUPERFAMILY SSF81301 23 212 4.25E-56 T 13-10-2018 CLOST_0722 6c6a640d5c3fbd92c3a1e43ba4f6f7e7 251 SMART SM00954 59 182 1.2E-45 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 CLOST_0722 6c6a640d5c3fbd92c3a1e43ba4f6f7e7 251 Gene3D G3DSA:1.10.287.860 165 228 1.6E-19 T 13-10-2018 CLOST_0722 6c6a640d5c3fbd92c3a1e43ba4f6f7e7 251 Pfam PF04607 Region found in RelA / SpoT proteins 59 180 1.5E-36 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 CLOST_0003 1ba0cc6df3b7725ccae2e1f0a7549dfb 68 Pfam PF13275 S4 domain 4 67 1.9E-24 T 13-10-2018 CLOST_0003 1ba0cc6df3b7725ccae2e1f0a7549dfb 68 Gene3D G3DSA:3.10.290.10 1 68 4.0E-24 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_0003 1ba0cc6df3b7725ccae2e1f0a7549dfb 68 SUPERFAMILY SSF55174 1 67 9.29E-18 T 13-10-2018 CLOST_0866 f2c3f71ae301f53cd4f0911a893294a5 249 SUPERFAMILY SSF109998 6 145 5.49E-19 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily CLOST_0866 f2c3f71ae301f53cd4f0911a893294a5 249 SUPERFAMILY SSF54534 108 204 3.62E-35 T 13-10-2018 CLOST_0866 f2c3f71ae301f53cd4f0911a893294a5 249 Gene3D G3DSA:1.10.4030.30 74 222 1.3E-40 T 13-10-2018 CLOST_0866 f2c3f71ae301f53cd4f0911a893294a5 249 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 144 164 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CLOST_0866 f2c3f71ae301f53cd4f0911a893294a5 249 Pfam PF13616 PPIC-type PPIASE domain 109 206 5.5E-27 T 13-10-2018 CLOST_0866 f2c3f71ae301f53cd4f0911a893294a5 249 Gene3D G3DSA:3.10.50.40 116 206 1.3E-40 T 13-10-2018 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 SUPERFAMILY SSF52440 1 131 2.78E-35 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 Gene3D G3DSA:3.40.50.20 1 121 1.4E-33 T 13-10-2018 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 Gene3D G3DSA:3.30.1490.20 147 216 1.4E-53 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 Gene3D G3DSA:3.30.470.20 122 298 1.4E-53 T 13-10-2018 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 SUPERFAMILY SSF56059 132 297 3.18E-40 T 13-10-2018 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 99 110 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 Pfam PF07478 D-ala D-ala ligase C-terminus 141 298 5.0E-49 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 305 28.262 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 Pfam PF01820 D-ala D-ala ligase N-terminus 2 122 2.8E-32 T 13-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 3 299 9.4E-87 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0933 21c8a3c5a4e2450b408bef9058086556 306 PIRSF PIRSF039102 1 302 1.4E-90 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_2088 7274cf04a1d8da552c1150f0a19a8054 282 Gene3D G3DSA:3.20.20.70 28 257 1.2E-18 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_2088 7274cf04a1d8da552c1150f0a19a8054 282 TIGRFAM TIGR00510 lipA: lipoyl synthase 2 278 2.1E-110 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CLOST_2088 7274cf04a1d8da552c1150f0a19a8054 282 SMART SM00729 49 257 8.7E-12 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_2088 7274cf04a1d8da552c1150f0a19a8054 282 Pfam PF04055 Radical SAM superfamily 55 214 1.9E-11 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_2088 7274cf04a1d8da552c1150f0a19a8054 282 Hamap MF_00206 Lipoyl synthase [lipA]. 1 282 125.089 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CLOST_2088 7274cf04a1d8da552c1150f0a19a8054 282 PIRSF PIRSF005963 1 281 3.5E-127 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CLOST_2088 7274cf04a1d8da552c1150f0a19a8054 282 SUPERFAMILY SSF102114 26 275 3.27E-50 T 13-10-2018 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 122 133 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 SUPERFAMILY SSF55190 9 105 1.31E-23 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 SUPERFAMILY SSF52374 109 444 2.98E-102 T 13-10-2018 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 Gene3D G3DSA:1.10.730.10 444 566 1.3E-39 T 13-10-2018 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 566 4.7E-166 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 Pfam PF05746 DALR anticodon binding domain 450 566 1.2E-32 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 1.5E-22 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 1.5E-22 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 1.5E-22 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 1.5E-22 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 83 2.3E-16 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 SMART SM00836 450 566 5.2E-44 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 566 26.453 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 SUPERFAMILY SSF47323 446 566 1.63E-33 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 Gene3D G3DSA:3.30.1360.70 2 105 9.9E-29 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 SMART SM01016 1 84 4.1E-20 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 Pfam PF00750 tRNA synthetases class I (R) 94 436 1.5E-98 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CLOST_1149 08046586e8db5702c60d09b76ec70337 566 Gene3D G3DSA:3.40.50.620 107 443 4.0E-129 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1605 e44a5f77219dd6eaef9601de1528eaca 240 SUPERFAMILY SSF52540 1 234 4.83E-78 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1605 e44a5f77219dd6eaef9601de1528eaca 240 Pfam PF00005 ABC transporter 17 165 6.5E-36 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1605 e44a5f77219dd6eaef9601de1528eaca 240 PIRSF PIRSF039085 1 240 8.0E-111 T 13-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CLOST_1605 e44a5f77219dd6eaef9601de1528eaca 240 Gene3D G3DSA:3.40.50.300 1 240 2.7E-76 T 13-10-2018 CLOST_1605 e44a5f77219dd6eaef9601de1528eaca 240 SMART SM00382 26 213 1.6E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1605 e44a5f77219dd6eaef9601de1528eaca 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1581 34852b83513d075b8b428ab7bbc70187 121 Hamap MF_00245 UPF0122 protein . 3 106 17.768 T 13-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CLOST_1581 34852b83513d075b8b428ab7bbc70187 121 Gene3D G3DSA:1.10.10.10 1 119 6.1E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1581 34852b83513d075b8b428ab7bbc70187 121 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 4 93 1.4E-24 T 13-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CLOST_1581 34852b83513d075b8b428ab7bbc70187 121 SUPERFAMILY SSF88659 2 94 3.36E-25 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 Gene3D G3DSA:3.10.580.10 66 214 3.9E-46 T 13-10-2018 CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 PIRSF PIRSF026546 6 214 7.1E-86 T 13-10-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 SUPERFAMILY SSF54631 73 209 2.99E-20 T 13-10-2018 CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 Pfam PF08279 HTH domain 11 63 2.8E-10 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 SMART SM00116 88 135 9.3 T 13-10-2018 IPR000644 CBS domain CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 SMART SM00116 154 209 6.9E-5 T 13-10-2018 IPR000644 CBS domain CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 SUPERFAMILY SSF46785 8 80 1.13E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 Gene3D G3DSA:1.10.10.10 1 65 4.3E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 Pfam PF00571 CBS domain 149 209 2.5E-9 T 13-10-2018 IPR000644 CBS domain CLOST_1769 977e0e2dc36f0004b74b488f7a81f92b 214 Pfam PF00571 CBS domain 83 132 0.0034 T 13-10-2018 IPR000644 CBS domain CLOST_2410 48b2a1676701a19bd5c0462606eaf9ed 307 SUPERFAMILY SSF53822 41 306 4.85E-88 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_2410 48b2a1676701a19bd5c0462606eaf9ed 307 Pfam PF13407 Periplasmic binding protein domain 42 292 4.4E-66 T 13-10-2018 IPR025997 Periplasmic binding protein CLOST_2410 48b2a1676701a19bd5c0462606eaf9ed 307 Gene3D G3DSA:3.40.50.2300 44 292 4.7E-96 T 13-10-2018 CLOST_2410 48b2a1676701a19bd5c0462606eaf9ed 307 Gene3D G3DSA:3.40.50.2300 140 274 4.7E-96 T 13-10-2018 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 Gene3D G3DSA:3.40.190.80 144 257 6.9E-18 T 13-10-2018 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 SUPERFAMILY SSF56655 9 240 4.58E-67 T 13-10-2018 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 186 207 1.5E-38 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 217 241 1.5E-38 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 1.5E-38 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 1.5E-38 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 1.5E-38 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 1.5E-38 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 Pfam PF00459 Inositol monophosphatase family 9 239 2.4E-51 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CLOST_1087 5dd561f27ca3bd7ed82f59c8ecdad21b 258 Gene3D G3DSA:3.30.540.10 2 143 1.1E-45 T 13-10-2018 CLOST_1938 7b80d1bfa1ec46cc86008046624ab24e 266 Gene3D G3DSA:2.60.200.30 105 244 6.7E-67 T 13-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CLOST_1938 7b80d1bfa1ec46cc86008046624ab24e 266 Gene3D G3DSA:3.40.50.10330 35 266 6.7E-67 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 CLOST_1938 7b80d1bfa1ec46cc86008046624ab24e 266 Pfam PF01513 ATP-NAD kinase 37 229 1.2E-33 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CLOST_1938 7b80d1bfa1ec46cc86008046624ab24e 266 Hamap MF_00361 NAD kinase [nadK]. 3 266 23.366 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CLOST_1938 7b80d1bfa1ec46cc86008046624ab24e 266 SUPERFAMILY SSF111331 6 265 4.58E-57 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily CLOST_0901 12e59b64669fc07b657523a76590844e 403 SUPERFAMILY SSF51735 1 150 3.95E-32 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0901 12e59b64669fc07b657523a76590844e 403 Gene3D G3DSA:3.30.360.10 128 328 1.8E-110 T 13-10-2018 CLOST_0901 12e59b64669fc07b657523a76590844e 403 PIRSF PIRSF036497 1 315 1.1E-86 T 13-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CLOST_0901 12e59b64669fc07b657523a76590844e 403 Gene3D G3DSA:3.30.70.260 329 340 1.8E-110 T 13-10-2018 CLOST_0901 12e59b64669fc07b657523a76590844e 403 SUPERFAMILY SSF55347 129 294 7.19E-43 T 13-10-2018 CLOST_0901 12e59b64669fc07b657523a76590844e 403 Gene3D G3DSA:3.40.50.720 2 324 1.8E-110 T 13-10-2018 CLOST_0901 12e59b64669fc07b657523a76590844e 403 Pfam PF00742 Homoserine dehydrogenase 129 307 3.6E-56 T 13-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CLOST_0901 12e59b64669fc07b657523a76590844e 403 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 175 197 - T 13-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CLOST_0901 12e59b64669fc07b657523a76590844e 403 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 7 121 1.5E-14 T 13-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CLOST_1024 aa9208459fa6519fe742ab366edd889f 340 SUPERFAMILY SSF54862 172 234 7.41E-19 T 13-10-2018 CLOST_1024 aa9208459fa6519fe742ab366edd889f 340 Pfam PF04015 Domain of unknown function (DUF362) 41 303 1.6E-30 T 13-10-2018 IPR007160 Domain of unknown function DUF362 CLOST_1024 aa9208459fa6519fe742ab366edd889f 340 Gene3D G3DSA:3.30.70.20 159 210 2.6E-6 T 13-10-2018 CLOST_1024 aa9208459fa6519fe742ab366edd889f 340 Gene3D G3DSA:3.30.70.20 211 254 1.2E-6 T 13-10-2018 CLOST_1024 aa9208459fa6519fe742ab366edd889f 340 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 218 229 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1024 aa9208459fa6519fe742ab366edd889f 340 Pfam PF14697 4Fe-4S dicluster domain 186 233 8.0E-10 T 13-10-2018 CLOST_1860 139aa31317dfba77eaa4f0dea9e55202 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 183 1.5E-70 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CLOST_1860 139aa31317dfba77eaa4f0dea9e55202 204 Gene3D G3DSA:3.40.50.300 9 182 8.0E-63 T 13-10-2018 CLOST_1860 139aa31317dfba77eaa4f0dea9e55202 204 SMART SM00072 4 186 7.4E-58 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CLOST_1860 139aa31317dfba77eaa4f0dea9e55202 204 Hamap MF_00328 Guanylate kinase [gmk]. 3 186 35.151 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CLOST_1860 139aa31317dfba77eaa4f0dea9e55202 204 Pfam PF00625 Guanylate kinase 7 184 4.4E-45 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CLOST_1860 139aa31317dfba77eaa4f0dea9e55202 204 Gene3D G3DSA:3.30.63.10 36 95 8.0E-63 T 13-10-2018 CLOST_1860 139aa31317dfba77eaa4f0dea9e55202 204 SUPERFAMILY SSF52540 3 189 8.26E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1860 139aa31317dfba77eaa4f0dea9e55202 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 39 56 - T 13-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CLOST_0400 775865ed8419d770a889854f7fda98b1 338 Gene3D G3DSA:3.90.70.10 26 202 1.1E-36 T 13-10-2018 CLOST_0400 775865ed8419d770a889854f7fda98b1 338 SUPERFAMILY SSF54001 90 205 2.53E-6 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_0400 775865ed8419d770a889854f7fda98b1 338 Pfam PF13529 Peptidase_C39 like family 31 189 4.9E-25 T 13-10-2018 IPR039564 Peptidase C39-like CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 Gene3D G3DSA:1.10.8.540 485 573 7.1E-29 T 13-10-2018 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 Gene3D G3DSA:1.10.490.80 575 673 4.6E-23 T 13-10-2018 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 1.9E-56 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 1.9E-56 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 1.9E-56 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 1.9E-56 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 1.9E-56 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 1.9E-56 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 PIRSF PIRSF005419 1 675 2.5E-260 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 5 673 3.0E-268 T 13-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 13-10-2018 IPR025505 FHIPEP conserved site CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 Pfam PF00771 FHIPEP family 15 665 1.7E-272 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CLOST_1719 92812bb847fcbb1ffee7458f8ccf7ed2 675 Gene3D G3DSA:3.40.30.60 342 484 1.7E-55 T 13-10-2018 CLOST_2021 58c5ce7bc16d504d9340c999e289e8e8 295 SUPERFAMILY SSF54862 58 118 4.23E-19 T 13-10-2018 CLOST_2021 58c5ce7bc16d504d9340c999e289e8e8 295 Pfam PF14697 4Fe-4S dicluster domain 62 114 5.2E-11 T 13-10-2018 CLOST_2021 58c5ce7bc16d504d9340c999e289e8e8 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 97 108 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2021 58c5ce7bc16d504d9340c999e289e8e8 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 262 6.7E-20 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOST_2021 58c5ce7bc16d504d9340c999e289e8e8 295 SUPERFAMILY SSF52540 1 284 5.64E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2021 58c5ce7bc16d504d9340c999e289e8e8 295 Gene3D G3DSA:3.30.70.20 67 116 4.9E-13 T 13-10-2018 CLOST_2013 73a27dc44b96298327f258a802729dd2 384 Gene3D G3DSA:3.90.1150.10 3 374 1.6E-103 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_2013 73a27dc44b96298327f258a802729dd2 384 SUPERFAMILY SSF53383 3 382 8.78E-86 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_2013 73a27dc44b96298327f258a802729dd2 384 Gene3D G3DSA:3.40.640.10 17 266 1.6E-103 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_2013 73a27dc44b96298327f258a802729dd2 384 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 3 380 2.3E-128 T 13-10-2018 IPR010969 Cysteine desulfurase-related, unknown function CLOST_2013 73a27dc44b96298327f258a802729dd2 384 Pfam PF00266 Aminotransferase class-V 3 373 5.5E-79 T 13-10-2018 IPR000192 Aminotransferase class V domain CLOST_0981 24bdb47db93562f281e8c5df541c5f66 456 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 190 1.8E-22 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOST_0981 24bdb47db93562f281e8c5df541c5f66 456 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 3 444 2.0E-143 T 13-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CLOST_0981 24bdb47db93562f281e8c5df541c5f66 456 Gene3D G3DSA:3.40.50.880 247 455 8.2E-12 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0981 24bdb47db93562f281e8c5df541c5f66 456 Gene3D G3DSA:3.40.50.300 2 188 1.2E-32 T 13-10-2018 CLOST_0981 24bdb47db93562f281e8c5df541c5f66 456 SUPERFAMILY SSF52540 1 196 8.42E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0981 24bdb47db93562f281e8c5df541c5f66 456 SUPERFAMILY SSF52317 244 444 1.07E-33 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0981 24bdb47db93562f281e8c5df541c5f66 456 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 246 437 4.0E-40 T 13-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CLOST_0981 24bdb47db93562f281e8c5df541c5f66 456 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 1 438 43.11 T 13-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CLOST_1929 3459cace4346a44c6909fadf445c4c18 392 Gene3D G3DSA:3.30.565.10 245 385 3.3E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1929 3459cace4346a44c6909fadf445c4c18 392 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 290 380 5.1E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1929 3459cace4346a44c6909fadf445c4c18 392 SUPERFAMILY SSF55874 250 378 3.01E-19 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1929 3459cace4346a44c6909fadf445c4c18 392 Pfam PF07730 Histidine kinase 180 246 2.8E-14 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CLOST_1929 3459cace4346a44c6909fadf445c4c18 392 SMART SM00387 285 381 3.0E-4 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1929 3459cace4346a44c6909fadf445c4c18 392 Pfam PF05384 Sensor protein DegS 12 170 1.1E-46 T 13-10-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 CLOST_2280 a80daa060152e9df89befbb7ece1478b 342 Pfam PF09084 NMT1/THI5 like 85 276 6.4E-9 T 13-10-2018 IPR015168 SsuA/THI5-like CLOST_2280 a80daa060152e9df89befbb7ece1478b 342 SUPERFAMILY SSF53850 47 325 2.56E-33 T 13-10-2018 CLOST_2280 a80daa060152e9df89befbb7ece1478b 342 Gene3D G3DSA:3.40.190.10 127 237 4.7E-94 T 13-10-2018 CLOST_2280 a80daa060152e9df89befbb7ece1478b 342 Gene3D G3DSA:3.40.190.10 50 338 4.7E-94 T 13-10-2018 CLOST_2280 a80daa060152e9df89befbb7ece1478b 342 PIRSF PIRSF027386 1 342 7.8E-110 T 13-10-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type CLOST_2190 12e5a8dd5615b46dc36b3b55379646f4 65 Pfam PF00831 Ribosomal L29 protein 4 60 5.6E-26 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2190 12e5a8dd5615b46dc36b3b55379646f4 65 Gene3D G3DSA:1.10.287.310 1 65 1.5E-28 T 13-10-2018 CLOST_2190 12e5a8dd5615b46dc36b3b55379646f4 65 SUPERFAMILY SSF46561 1 63 6.54E-24 T 13-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2190 12e5a8dd5615b46dc36b3b55379646f4 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 4.4E-25 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2190 12e5a8dd5615b46dc36b3b55379646f4 65 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 13-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2190 12e5a8dd5615b46dc36b3b55379646f4 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.9 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 176 189 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 SMART SM00382 172 313 1.3E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 Gene3D G3DSA:3.30.450.20 18 129 6.1E-12 T 13-10-2018 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 Pfam PF00158 Sigma-54 interaction domain 153 317 2.4E-59 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 SUPERFAMILY SSF52540 151 388 3.24E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 444 463 3.4E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 444 3.4E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 Pfam PF02954 Bacterial regulatory protein, Fis family 421 461 3.2E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 Gene3D G3DSA:1.10.10.60 405 463 5.6E-14 T 13-10-2018 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 Gene3D G3DSA:3.40.50.300 138 321 1.3E-58 T 13-10-2018 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 SUPERFAMILY SSF46689 364 463 3.48E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 SUPERFAMILY SSF55785 13 113 7.23E-9 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 237 252 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 Gene3D G3DSA:1.10.8.60 322 389 1.3E-20 T 13-10-2018 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 364 373 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 Pfam PF00989 PAS fold 10 109 3.2E-5 T 13-10-2018 IPR013767 PAS fold GO:0006355 CLOST_1295 cbf0174caa2115803476c914fb338bc3 463 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 125 5.9E-9 T 13-10-2018 IPR000014 PAS domain CLOST_0554 795a489a988d82ae0e625f96ed83baaa 264 Pfam PF14512 Putative TM nitroreductase 3 231 3.8E-25 T 13-10-2018 IPR029478 Putative nitroreductase TM1586 CLOST_0554 795a489a988d82ae0e625f96ed83baaa 264 SUPERFAMILY SSF55469 7 139 4.71E-18 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_0554 795a489a988d82ae0e625f96ed83baaa 264 Gene3D G3DSA:3.40.109.10 172 260 3.8E-5 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_0554 795a489a988d82ae0e625f96ed83baaa 264 SUPERFAMILY SSF55469 179 239 5.23E-6 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_0554 795a489a988d82ae0e625f96ed83baaa 264 Gene3D G3DSA:3.40.109.10 1 169 2.0E-20 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 501 52.322 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 92 2.6E-17 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 PIRSF PIRSF039088 1 503 1.3E-263 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.4E-74 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 SUPERFAMILY SSF47917 372 500 4.71E-47 T 13-10-2018 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 SUPERFAMILY SSF50615 10 94 6.08E-30 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 Gene3D G3DSA:3.40.50.300 94 371 1.7E-129 T 13-10-2018 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 Gene3D G3DSA:1.20.150.20 372 504 1.3E-51 T 13-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 SUPERFAMILY SSF52540 96 370 2.25E-102 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 Gene3D G3DSA:2.40.30.20 1 93 3.9E-37 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 500 1.5E-260 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2118 6c3d68325174f3081e44ad89db8b503d 504 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 496 9.1E-51 T 13-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2074 772b81f7b1621ca465a210fedf0890ad 253 SUPERFAMILY SSF64167 1 250 9.42E-63 T 13-10-2018 CLOST_2074 772b81f7b1621ca465a210fedf0890ad 253 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 235 4.9E-51 T 13-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CLOST_2074 772b81f7b1621ca465a210fedf0890ad 253 Gene3D G3DSA:3.40.1210.10 1 252 7.5E-70 T 13-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CLOST_2074 772b81f7b1621ca465a210fedf0890ad 253 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 252 27.598 T 13-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CLOST_2074 772b81f7b1621ca465a210fedf0890ad 253 Pfam PF01975 Survival protein SurE 3 190 3.8E-52 T 13-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 SMART SM00930 247 320 2.7E-10 T 13-10-2018 IPR018449 NIL domain CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 Gene3D G3DSA:3.40.50.300 1 235 4.9E-75 T 13-10-2018 CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 SMART SM00382 26 214 6.2E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 SUPERFAMILY SSF55021 240 322 1.26E-11 T 13-10-2018 CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 Gene3D G3DSA:3.30.70.260 236 322 2.3E-7 T 13-10-2018 CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 Pfam PF09383 NIL domain 250 316 2.5E-9 T 13-10-2018 IPR018449 NIL domain CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 Pfam PF00005 ABC transporter 18 165 5.4E-37 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 SUPERFAMILY SSF52540 2 229 6.72E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0089 1bf27101a71755bfa9c9611f3e9ba541 324 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0735 e6bd6a3711dcf6c7e8c568363eaea9f9 688 Pfam PF03235 Protein of unknown function DUF262 8 220 3.7E-36 T 13-10-2018 IPR004919 Domain of unknown function DUF262 CLOST_0735 e6bd6a3711dcf6c7e8c568363eaea9f9 688 Pfam PF07510 Protein of unknown function (DUF1524) 413 552 1.0E-23 T 13-10-2018 IPR011089 Domain of unknown function DUF1524 CLOST_0679 9c8ad0f4c192862bfd666587ce5f61f3 216 PIRSF PIRSF010130 1 216 9.1E-80 T 13-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 CLOST_0679 9c8ad0f4c192862bfd666587ce5f61f3 216 Pfam PF06130 Phosphate propanoyltransferase 32 111 7.8E-27 T 13-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 CLOST_0679 9c8ad0f4c192862bfd666587ce5f61f3 216 Pfam PF06130 Phosphate propanoyltransferase 140 205 6.6E-21 T 13-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 CLOST_0537 d423a023ab48e4382fde45dc9694b37e 356 Gene3D G3DSA:3.30.360.10 137 337 3.4E-108 T 13-10-2018 CLOST_0537 d423a023ab48e4382fde45dc9694b37e 356 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 144 220 3.5E-12 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 CLOST_0537 d423a023ab48e4382fde45dc9694b37e 356 Gene3D G3DSA:3.40.50.720 12 323 3.4E-108 T 13-10-2018 CLOST_0537 d423a023ab48e4382fde45dc9694b37e 356 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 129 1.4E-19 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CLOST_0537 d423a023ab48e4382fde45dc9694b37e 356 SUPERFAMILY SSF51735 7 209 6.7E-41 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0189 2ddf0157b10f98e0922ec615b7664937 466 SUPERFAMILY SSF53300 198 342 1.07E-15 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily CLOST_0189 2ddf0157b10f98e0922ec615b7664937 466 SMART SM00327 196 445 1.7E-5 T 13-10-2018 IPR002035 von Willebrand factor, type A CLOST_0189 2ddf0157b10f98e0922ec615b7664937 466 Pfam PF13519 von Willebrand factor type A domain 200 332 5.8E-10 T 13-10-2018 IPR002035 von Willebrand factor, type A CLOST_0189 2ddf0157b10f98e0922ec615b7664937 466 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 27 5.4E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site CLOST_1749 74c1fbd95ac57f692a7f019d1f4d6de5 486 Pfam PF13200 Putative glycosyl hydrolase domain 166 483 9.2E-109 T 13-10-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 CLOST_1749 74c1fbd95ac57f692a7f019d1f4d6de5 486 Gene3D G3DSA:2.30.30.40 54 135 4.3E-10 T 13-10-2018 CLOST_1749 74c1fbd95ac57f692a7f019d1f4d6de5 486 SUPERFAMILY SSF51445 219 481 3.72E-7 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily CLOST_1749 74c1fbd95ac57f692a7f019d1f4d6de5 486 Pfam PF08239 Bacterial SH3 domain 73 121 7.9E-8 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type CLOST_1749 74c1fbd95ac57f692a7f019d1f4d6de5 486 SMART SM00287 64 135 7.6E-6 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 Gene3D G3DSA:3.30.420.40 160 339 1.3E-144 T 13-10-2018 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 SUPERFAMILY SSF53067 4 160 3.11E-58 T 13-10-2018 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 604 36.942 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 309 323 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 Gene3D G3DSA:3.90.640.10 200 281 1.3E-144 T 13-10-2018 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 Gene3D G3DSA:3.30.420.40 5 349 1.3E-144 T 13-10-2018 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 441 457 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 174 184 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 360 379 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 31 43 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 337 357 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 3 16 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 114 134 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 54 62 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 PRINTS PR00301 70kDa heat shock protein signature 306 322 9.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 Pfam PF00012 Hsp70 protein 5 578 2.0E-244 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 Gene3D G3DSA:1.20.1270.10 479 584 7.1E-26 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 SUPERFAMILY SSF100920 356 512 2.88E-60 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 Gene3D G3DSA:2.60.34.10 350 477 3.3E-57 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 SUPERFAMILY SSF100934 479 579 1.51E-11 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 SUPERFAMILY SSF53067 163 354 5.57E-65 T 13-10-2018 CLOST_1793 011304ba759bc5538c53b087c82f6a9e 608 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 577 6.4E-286 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 Pfam PF01628 HrcA protein C terminal domain 109 329 1.1E-51 T 13-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 9 344 4.4E-95 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 Gene3D G3DSA:1.10.10.10 1 88 1.4E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 SUPERFAMILY SSF55781 76 347 3.14E-49 T 13-10-2018 CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 PIRSF PIRSF005485 4 348 8.1E-95 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 Gene3D G3DSA:3.30.390.60 133 235 3.6E-42 T 13-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 6 338 27.697 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 SUPERFAMILY SSF46785 6 88 6.75E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1795 b2f80b0a00c88308349b9e8155e0b48f 348 Gene3D G3DSA:3.30.450.40 110 344 3.6E-42 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_2026 e8dfc93b86649012dc2f23132d04e61a 250 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 242 1.6E-24 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase CLOST_2026 e8dfc93b86649012dc2f23132d04e61a 250 Gene3D G3DSA:3.60.10.10 1 249 1.2E-98 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily CLOST_2026 e8dfc93b86649012dc2f23132d04e61a 250 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 249 8.3E-99 T 13-10-2018 CLOST_2026 e8dfc93b86649012dc2f23132d04e61a 250 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 249 1.7E-101 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CLOST_2026 e8dfc93b86649012dc2f23132d04e61a 250 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CLOST_2026 e8dfc93b86649012dc2f23132d04e61a 250 SUPERFAMILY SSF56219 1 249 3.4E-82 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily CLOST_2164 7c97f319361e597432ac9ff17df470ee 267 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 264 35.008 T 13-10-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 CLOST_2164 7c97f319361e597432ac9ff17df470ee 267 Pfam PF02361 Cobalt transport protein 15 234 9.4E-51 T 13-10-2018 IPR003339 ABC/ECF transporter, transmembrane component CLOST_0427 a4f053225788e059a04f7953b34d9bb7 126 Pfam PF01597 Glycine cleavage H-protein 6 124 2.1E-38 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate CLOST_0427 a4f053225788e059a04f7953b34d9bb7 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 5 125 1.4E-38 T 13-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CLOST_0427 a4f053225788e059a04f7953b34d9bb7 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 3 123 34.49 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CLOST_0427 a4f053225788e059a04f7953b34d9bb7 126 SUPERFAMILY SSF51230 4 124 1.7E-35 T 13-10-2018 IPR011053 Single hybrid motif CLOST_0427 a4f053225788e059a04f7953b34d9bb7 126 Gene3D G3DSA:2.40.50.100 1 125 7.8E-45 T 13-10-2018 CLOST_0427 a4f053225788e059a04f7953b34d9bb7 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 46 75 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CLOST_0048 fd2bbd824eed84e937d646675d0424ca 932 Hamap MF_01600 UPF0182 protein . 9 867 18.077 T 13-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CLOST_0048 fd2bbd824eed84e937d646675d0424ca 932 Pfam PF03699 Uncharacterised protein family (UPF0182) 19 791 1.1E-269 T 13-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CLOST_0210 8a05951b37454f912eabb7d8449bf55d 182 Gene3D G3DSA:1.10.530.10 52 182 2.0E-26 T 13-10-2018 CLOST_0210 8a05951b37454f912eabb7d8449bf55d 182 Pfam PF01464 Transglycosylase SLT domain 58 159 1.4E-21 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 CLOST_0210 8a05951b37454f912eabb7d8449bf55d 182 SUPERFAMILY SSF53955 45 155 1.18E-26 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily CLOST_0603 879c009c28faae8d2162cab6514dcc1c 435 SUPERFAMILY SSF53850 37 406 1.18E-75 T 13-10-2018 CLOST_0603 879c009c28faae8d2162cab6514dcc1c 435 Gene3D G3DSA:3.40.190.10 54 381 3.5E-99 T 13-10-2018 CLOST_0603 879c009c28faae8d2162cab6514dcc1c 435 Pfam PF01547 Bacterial extracellular solute-binding protein 53 344 7.7E-34 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein CLOST_0603 879c009c28faae8d2162cab6514dcc1c 435 Gene3D G3DSA:3.40.190.10 150 417 3.5E-99 T 13-10-2018 CLOST_1846 3acc7d56e5fbe12b5ae1e18444b54ddd 215 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 150 204 3.2E-14 T 13-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_1846 3acc7d56e5fbe12b5ae1e18444b54ddd 215 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 209 3.9E-61 T 13-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_1846 3acc7d56e5fbe12b5ae1e18444b54ddd 215 SMART SM00983 142 207 9.5E-17 T 13-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_1846 3acc7d56e5fbe12b5ae1e18444b54ddd 215 SUPERFAMILY SSF63999 2 132 6.93E-38 T 13-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_1846 3acc7d56e5fbe12b5ae1e18444b54ddd 215 SUPERFAMILY SSF63862 133 206 4.97E-10 T 13-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_1846 3acc7d56e5fbe12b5ae1e18444b54ddd 215 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 20 125 1.0E-29 T 13-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_1846 3acc7d56e5fbe12b5ae1e18444b54ddd 215 Gene3D G3DSA:3.40.50.10240 1 214 2.4E-64 T 13-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_1739 519561d2035c436da40efcbbb9c1ee16 265 SUPERFAMILY SSF160527 158 259 4.45E-5 T 13-10-2018 CLOST_1739 519561d2035c436da40efcbbb9c1ee16 265 Pfam PF02108 Flagellar assembly protein FliH 124 251 1.0E-14 T 13-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CLOST_1930 0bc3ba0a0a7baa8820aa2b6e611d66bf 149 SMART SM00260 1 138 7.7E-41 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 CLOST_1930 0bc3ba0a0a7baa8820aa2b6e611d66bf 149 SUPERFAMILY SSF50341 2 142 3.92E-37 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 CLOST_1930 0bc3ba0a0a7baa8820aa2b6e611d66bf 149 Gene3D G3DSA:2.30.30.40 7 132 4.9E-43 T 13-10-2018 CLOST_1930 0bc3ba0a0a7baa8820aa2b6e611d66bf 149 Gene3D G3DSA:2.40.50.180 24 133 4.9E-43 T 13-10-2018 CLOST_1930 0bc3ba0a0a7baa8820aa2b6e611d66bf 149 Pfam PF01584 CheW-like domain 6 141 1.8E-36 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 CLOST_1500 d556b5f873a56d18baca6f1fecfbcfbe 125 Gene3D G3DSA:3.40.50.300 12 123 3.4E-8 T 13-10-2018 CLOST_1500 d556b5f873a56d18baca6f1fecfbcfbe 125 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 22 117 1.7E-32 T 13-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CLOST_0076 df0684fe005c8fbe9d19145dfa69621a 311 SUPERFAMILY SSF90002 219 307 5.1E-7 T 13-10-2018 CLOST_0076 df0684fe005c8fbe9d19145dfa69621a 311 SUPERFAMILY SSF52540 5 188 2.7E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0076 df0684fe005c8fbe9d19145dfa69621a 311 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 179 4.6E-32 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CLOST_0076 df0684fe005c8fbe9d19145dfa69621a 311 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 222 306 1.5E-4 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CLOST_0076 df0684fe005c8fbe9d19145dfa69621a 311 Gene3D G3DSA:3.40.50.300 2 197 1.7E-38 T 13-10-2018 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 Gene3D G3DSA:3.30.160.40 221 296 2.3E-17 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 SUPERFAMILY SSF54782 220 294 3.01E-19 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 SUPERFAMILY SSF53850 1 216 3.36E-69 T 13-10-2018 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 211 7.3E-72 T 13-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 PIRSF PIRSF001438 1 304 2.6E-102 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 227 294 9.3E-15 T 13-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 PRINTS PR00151 Porphobilinogen deaminase signature 142 159 2.9E-38 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 PRINTS PR00151 Porphobilinogen deaminase signature 42 62 2.9E-38 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 2.9E-38 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 PRINTS PR00151 Porphobilinogen deaminase signature 123 140 2.9E-38 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 PRINTS PR00151 Porphobilinogen deaminase signature 73 92 2.9E-38 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 299 34.313 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 Gene3D G3DSA:3.40.190.10 100 201 1.5E-75 T 13-10-2018 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 293 9.8E-98 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CLOST_0998 44c14eaf651709a487e523d237bdc4ac 304 Gene3D G3DSA:3.40.190.10 3 208 1.5E-75 T 13-10-2018 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 Gene3D G3DSA:2.40.500.20 92 203 1.1E-46 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 9.4E-26 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 9.4E-26 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 9.4E-26 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 9.4E-26 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 9.4E-26 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 PIRSF PIRSF000349 1 203 2.7E-84 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 SUPERFAMILY SSF46609 1 91 4.32E-39 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 90 1.4E-32 T 13-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 198 1.6E-40 T 13-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 Gene3D G3DSA:1.10.287.990 20 90 1.7E-34 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 SUPERFAMILY SSF54719 89 200 5.89E-43 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1948 82a5b15edb19155345ffe461b06b7d86 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 13-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 SUPERFAMILY SSF47323 646 882 3.36E-51 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 Gene3D G3DSA:3.90.740.10 197 390 2.6E-245 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 Pfam PF08264 Anticodon-binding domain of tRNA 678 822 2.6E-29 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 8 834 1.3E-292 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 Gene3D G3DSA:3.40.50.620 15 617 2.6E-245 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 SUPERFAMILY SSF50677 207 379 6.17E-43 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 1 1028 13.568 T 13-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 SUPERFAMILY SSF52374 11 638 1.56E-135 T 13-10-2018 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 510 523 2.5E-28 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 221 244 2.5E-28 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 41 52 2.5E-28 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 384 399 2.5E-28 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 550 559 2.5E-28 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 Gene3D G3DSA:1.10.730.10 632 816 3.0E-49 T 13-10-2018 CLOST_1876 2f1de1af044e6f34d0da4c2004883421 1034 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 19 623 3.7E-187 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2450 09e8e9eb1987620931cf5177aba93341 199 SMART SM00530 9 64 8.1E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2450 09e8e9eb1987620931cf5177aba93341 199 Pfam PF01880 Desulfoferrodoxin 135 192 5.5E-5 T 13-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 CLOST_2450 09e8e9eb1987620931cf5177aba93341 199 SUPERFAMILY SSF47413 3 69 1.24E-14 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_2450 09e8e9eb1987620931cf5177aba93341 199 SUPERFAMILY SSF49367 118 193 9.55E-18 T 13-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 CLOST_2450 09e8e9eb1987620931cf5177aba93341 199 Pfam PF01381 Helix-turn-helix 11 61 2.7E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2450 09e8e9eb1987620931cf5177aba93341 199 Gene3D G3DSA:1.10.260.40 3 82 2.2E-16 T 13-10-2018 CLOST_2450 09e8e9eb1987620931cf5177aba93341 199 Gene3D G3DSA:2.60.40.730 83 193 2.9E-19 T 13-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 CLOST_2564 248f783821e175896aa9afb2cd1ad7b1 441 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 5 437 1.5E-175 T 13-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CLOST_2564 248f783821e175896aa9afb2cd1ad7b1 441 Gene3D G3DSA:3.40.50.300 164 440 4.0E-110 T 13-10-2018 CLOST_2564 248f783821e175896aa9afb2cd1ad7b1 441 SUPERFAMILY SSF48024 4 116 3.79E-34 T 13-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 CLOST_2564 248f783821e175896aa9afb2cd1ad7b1 441 Gene3D G3DSA:1.10.860.10 1 162 6.2E-53 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CLOST_2564 248f783821e175896aa9afb2cd1ad7b1 441 Pfam PF03796 DnaB-like helicase C terminal domain 181 435 4.3E-116 T 13-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CLOST_2564 248f783821e175896aa9afb2cd1ad7b1 441 SUPERFAMILY SSF52540 179 428 4.62E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2564 248f783821e175896aa9afb2cd1ad7b1 441 Pfam PF00772 DnaB-like helicase N terminal domain 6 107 7.8E-33 T 13-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CLOST_0045 42f92ed65187c795ad05d72454f90150 364 SUPERFAMILY SSF51419 11 236 9.16E-23 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_0045 42f92ed65187c795ad05d72454f90150 364 Pfam PF01168 Alanine racemase, N-terminal domain 11 232 1.7E-14 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_0045 42f92ed65187c795ad05d72454f90150 364 Gene3D G3DSA:3.20.20.10 13 228 6.9E-20 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_1034 ffe9348b9bbf6aa75fa884666e4b1310 1227 SUPERFAMILY SSF53335 90 673 9.97E-56 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1034 ffe9348b9bbf6aa75fa884666e4b1310 1227 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 259 275 1.3E-5 T 13-10-2018 CLOST_1034 ffe9348b9bbf6aa75fa884666e4b1310 1227 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 506 518 1.3E-5 T 13-10-2018 CLOST_1034 ffe9348b9bbf6aa75fa884666e4b1310 1227 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 539 563 1.3E-5 T 13-10-2018 CLOST_1034 ffe9348b9bbf6aa75fa884666e4b1310 1227 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 327 341 1.3E-5 T 13-10-2018 CLOST_1034 ffe9348b9bbf6aa75fa884666e4b1310 1227 Pfam PF07669 Eco57I restriction-modification methylase 505 586 5.0E-5 T 13-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 CLOST_0942 9077a15b2228eda1ba293208981811e8 513 Gene3D G3DSA:3.90.226.10 1 256 3.3E-93 T 13-10-2018 CLOST_0942 9077a15b2228eda1ba293208981811e8 513 SUPERFAMILY SSF52096 2 254 1.15E-78 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_0942 9077a15b2228eda1ba293208981811e8 513 Gene3D G3DSA:3.90.226.10 257 513 6.1E-93 T 13-10-2018 CLOST_0942 9077a15b2228eda1ba293208981811e8 513 SUPERFAMILY SSF52096 241 513 7.12E-92 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_0942 9077a15b2228eda1ba293208981811e8 513 Pfam PF01039 Carboxyl transferase domain 26 510 4.8E-200 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 Pfam PF00005 ABC transporter 272 425 3.0E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 SUPERFAMILY SSF52540 245 486 2.98E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 Gene3D G3DSA:3.40.50.300 244 495 3.1E-46 T 13-10-2018 CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 ProSitePatterns PS00211 ABC transporters family signature. 398 412 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 Pfam PF00005 ABC transporter 22 172 3.7E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 SMART SM00382 280 481 2.0E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 SMART SM00382 31 220 4.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 Gene3D G3DSA:3.40.50.300 3 237 7.6E-57 T 13-10-2018 CLOST_0771 e075b1b7250f689a782adfb6e447d0f1 496 SUPERFAMILY SSF52540 7 229 6.69E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1847 c478bcf7513941a534784edb4ca01b8d 218 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CLOST_1847 c478bcf7513941a534784edb4ca01b8d 218 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 3.5E-83 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CLOST_1847 c478bcf7513941a534784edb4ca01b8d 218 SUPERFAMILY SSF51366 1 214 9.42E-79 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CLOST_1847 c478bcf7513941a534784edb4ca01b8d 218 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CLOST_1847 c478bcf7513941a534784edb4ca01b8d 218 Gene3D G3DSA:3.20.20.70 1 217 1.1E-90 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1847 c478bcf7513941a534784edb4ca01b8d 218 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 212 2.2E-88 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CLOST_1847 c478bcf7513941a534784edb4ca01b8d 218 PIRSF PIRSF001461 1 217 1.1E-93 T 13-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CLOST_0780 c5402c82c16754d7ce79e0e80bf0744c 339 Pfam PF00005 ABC transporter 20 161 3.6E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0780 c5402c82c16754d7ce79e0e80bf0744c 339 SUPERFAMILY SSF52540 4 240 1.64E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0780 c5402c82c16754d7ce79e0e80bf0744c 339 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0780 c5402c82c16754d7ce79e0e80bf0744c 339 SUPERFAMILY SSF50331 237 334 1.53E-8 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CLOST_0780 c5402c82c16754d7ce79e0e80bf0744c 339 Gene3D G3DSA:3.40.50.300 1 237 2.6E-72 T 13-10-2018 CLOST_0780 c5402c82c16754d7ce79e0e80bf0744c 339 SMART SM00382 28 211 5.6E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2222 4d8e95d5ecc0b7a06fa449fb00a1addc 242 Pfam PF00588 SpoU rRNA Methylase family 94 233 2.5E-42 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CLOST_2222 4d8e95d5ecc0b7a06fa449fb00a1addc 242 Gene3D G3DSA:3.40.1280.10 74 240 7.6E-57 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CLOST_2222 4d8e95d5ecc0b7a06fa449fb00a1addc 242 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 4 76 2.0E-20 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CLOST_2222 4d8e95d5ecc0b7a06fa449fb00a1addc 242 Gene3D G3DSA:3.30.1330.30 1 72 9.8E-14 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like CLOST_2222 4d8e95d5ecc0b7a06fa449fb00a1addc 242 SUPERFAMILY SSF75217 65 240 9.81E-50 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases CLOST_2222 4d8e95d5ecc0b7a06fa449fb00a1addc 242 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 239 2.6E-79 T 13-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CLOST_2222 4d8e95d5ecc0b7a06fa449fb00a1addc 242 SMART SM00967 2 77 1.9E-18 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CLOST_2222 4d8e95d5ecc0b7a06fa449fb00a1addc 242 SUPERFAMILY SSF55315 3 73 2.0E-17 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like CLOST_0778 f0ee7b3a9b24e398dd011953b92b2c5a 288 SUPERFAMILY SSF161098 8 277 5.36E-38 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0778 f0ee7b3a9b24e398dd011953b92b2c5a 288 Gene3D G3DSA:1.10.3720.10 2 280 1.3E-42 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0778 f0ee7b3a9b24e398dd011953b92b2c5a 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 276 1.2E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0196 57a0db58bf130b9b8e819f0690166136 319 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 15 195 1.7E-55 T 13-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 CLOST_0196 57a0db58bf130b9b8e819f0690166136 319 Gene3D G3DSA:3.40.50.720 2 200 1.4E-59 T 13-10-2018 CLOST_0196 57a0db58bf130b9b8e819f0690166136 319 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 198 295 1.7E-20 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 CLOST_0196 57a0db58bf130b9b8e819f0690166136 319 PIRSF PIRSF000105 8 318 5.3E-81 T 13-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CLOST_0196 57a0db58bf130b9b8e819f0690166136 319 Gene3D G3DSA:1.10.1040.10 201 318 8.5E-34 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CLOST_0196 57a0db58bf130b9b8e819f0690166136 319 SUPERFAMILY SSF51735 12 194 5.0E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0196 57a0db58bf130b9b8e819f0690166136 319 SUPERFAMILY SSF48179 197 299 1.11E-19 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CLOST_0957 7f54ad6292fe9448afea62a011104920 170 Pfam PF13353 4Fe-4S single cluster domain 13 154 2.0E-35 T 13-10-2018 CLOST_0957 7f54ad6292fe9448afea62a011104920 170 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 4 156 5.3E-47 T 13-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CLOST_0957 7f54ad6292fe9448afea62a011104920 170 ProSitePatterns PS01087 Radical activating enzymes signature. 15 36 - T 13-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CLOST_0957 7f54ad6292fe9448afea62a011104920 170 Pfam PF04055 Radical SAM superfamily 21 88 2.6E-9 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0957 7f54ad6292fe9448afea62a011104920 170 PIRSF PIRSF000368 1 170 9.8E-52 T 13-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CLOST_0957 7f54ad6292fe9448afea62a011104920 170 Gene3D G3DSA:3.20.20.70 1 165 4.2E-32 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0957 7f54ad6292fe9448afea62a011104920 170 SUPERFAMILY SSF102114 20 91 6.28E-9 T 13-10-2018 CLOST_0873 47f5c3b6f35abc157406d84ff991bca7 229 SUPERFAMILY SSF161098 16 224 1.09E-34 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0873 47f5c3b6f35abc157406d84ff991bca7 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 228 1.3E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0873 47f5c3b6f35abc157406d84ff991bca7 229 Gene3D G3DSA:1.10.3720.10 6 229 1.1E-35 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0874 aa73c025f5856090f08feda53edf8582 241 SUPERFAMILY SSF52540 2 224 9.53E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0874 aa73c025f5856090f08feda53edf8582 241 Pfam PF00005 ABC transporter 17 160 4.7E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0874 aa73c025f5856090f08feda53edf8582 241 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0874 aa73c025f5856090f08feda53edf8582 241 SMART SM00382 26 210 2.7E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0874 aa73c025f5856090f08feda53edf8582 241 Gene3D G3DSA:3.40.50.300 2 235 1.4E-66 T 13-10-2018 CLOST_0689 657b240b114489070381833066fc14af 354 Pfam PF01008 Initiation factor 2 subunit family 51 342 3.9E-76 T 13-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CLOST_0689 657b240b114489070381833066fc14af 354 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 352 37.959 T 13-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CLOST_0689 657b240b114489070381833066fc14af 354 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 38 341 1.4E-107 T 13-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CLOST_0689 657b240b114489070381833066fc14af 354 Gene3D G3DSA:3.40.50.10470 153 354 1.2E-65 T 13-10-2018 CLOST_0689 657b240b114489070381833066fc14af 354 Gene3D G3DSA:1.20.120.420 3 152 2.5E-44 T 13-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CLOST_0689 657b240b114489070381833066fc14af 354 SUPERFAMILY SSF100950 16 346 4.27E-114 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_0689 657b240b114489070381833066fc14af 354 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 16 340 1.3E-127 T 13-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CLOST_1732 7d59d8cedd8b347bca7b0ca879680aa1 69 Pfam PF06289 Flagellar protein (FlbD) 1 56 2.0E-28 T 13-10-2018 IPR009384 Swarming motility protein SwrD-like CLOST_2243 03a627e3d34eeae8d3a0264e6c6a731d 304 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 301 5.0E-126 T 13-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CLOST_2243 03a627e3d34eeae8d3a0264e6c6a731d 304 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 13-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CLOST_2243 03a627e3d34eeae8d3a0264e6c6a731d 304 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 289 4.5E-72 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_2243 03a627e3d34eeae8d3a0264e6c6a731d 304 Gene3D G3DSA:3.40.50.1100 44 142 9.9E-115 T 13-10-2018 CLOST_2243 03a627e3d34eeae8d3a0264e6c6a731d 304 SUPERFAMILY SSF53686 1 301 1.7E-98 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_2243 03a627e3d34eeae8d3a0264e6c6a731d 304 Gene3D G3DSA:3.40.50.1100 5 297 9.9E-115 T 13-10-2018 CLOST_2243 03a627e3d34eeae8d3a0264e6c6a731d 304 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 301 8.2E-122 T 13-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CLOST_1396 d9684df77f8ce638a724ad3df6353477 191 Pfam PF02545 Maf-like protein 3 184 8.2E-51 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 CLOST_1396 d9684df77f8ce638a724ad3df6353477 191 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 182 2.0E-49 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 CLOST_1396 d9684df77f8ce638a724ad3df6353477 191 PIRSF PIRSF006305 1 191 2.3E-54 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 CLOST_1396 d9684df77f8ce638a724ad3df6353477 191 SUPERFAMILY SSF52972 2 184 1.18E-54 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CLOST_1396 d9684df77f8ce638a724ad3df6353477 191 Hamap MF_00528 Septum formation protein Maf [maf]. 2 189 27.338 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 CLOST_1396 d9684df77f8ce638a724ad3df6353477 191 Gene3D G3DSA:3.90.950.10 1 186 1.7E-61 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CLOST_0476 2b9eaff3a5dea4d61594b41f4692915c 354 SUPERFAMILY SSF54534 180 287 3.21E-30 T 13-10-2018 CLOST_0476 2b9eaff3a5dea4d61594b41f4692915c 354 Pfam PF13624 SurA N-terminal domain 4 147 5.9E-17 T 13-10-2018 CLOST_0476 2b9eaff3a5dea4d61594b41f4692915c 354 Gene3D G3DSA:3.10.50.40 180 287 2.3E-57 T 13-10-2018 CLOST_0476 2b9eaff3a5dea4d61594b41f4692915c 354 SUPERFAMILY SSF109998 27 194 2.67E-27 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily CLOST_0476 2b9eaff3a5dea4d61594b41f4692915c 354 Gene3D G3DSA:1.10.4030.30 30 307 2.3E-57 T 13-10-2018 CLOST_0476 2b9eaff3a5dea4d61594b41f4692915c 354 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 224 245 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CLOST_0476 2b9eaff3a5dea4d61594b41f4692915c 354 Pfam PF13616 PPIC-type PPIASE domain 166 287 5.2E-34 T 13-10-2018 CLOST_0138 948916dc03b667b3b29d17f4b33b156f 417 Pfam PF01960 ArgJ family 29 415 5.9E-139 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CLOST_0138 948916dc03b667b3b29d17f4b33b156f 417 Gene3D G3DSA:3.10.20.340 284 417 1.6E-41 T 13-10-2018 CLOST_0138 948916dc03b667b3b29d17f4b33b156f 417 SUPERFAMILY SSF56266 23 413 3.53E-128 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CLOST_0138 948916dc03b667b3b29d17f4b33b156f 417 Gene3D G3DSA:3.60.70.12 10 198 5.0E-65 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CLOST_0138 948916dc03b667b3b29d17f4b33b156f 417 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 16 415 1.1E-140 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CLOST_0138 948916dc03b667b3b29d17f4b33b156f 417 Gene3D G3DSA:3.30.2330.10 199 283 9.4E-28 T 13-10-2018 CLOST_0138 948916dc03b667b3b29d17f4b33b156f 417 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 40 415 7.0E-113 T 13-10-2018 CLOST_0138 948916dc03b667b3b29d17f4b33b156f 417 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 417 130.437 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CLOST_0893 aab1ba2cc76dc10ccd9c60b1e9398917 151 SMART SM00347 28 128 6.3E-17 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0893 aab1ba2cc76dc10ccd9c60b1e9398917 151 Gene3D G3DSA:1.10.10.10 4 143 2.2E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0893 aab1ba2cc76dc10ccd9c60b1e9398917 151 SUPERFAMILY SSF46785 11 144 1.26E-27 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0893 aab1ba2cc76dc10ccd9c60b1e9398917 151 Pfam PF01047 MarR family 35 93 1.0E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0893 aab1ba2cc76dc10ccd9c60b1e9398917 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 6.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0893 aab1ba2cc76dc10ccd9c60b1e9398917 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 6.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0893 aab1ba2cc76dc10ccd9c60b1e9398917 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 6.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0893 aab1ba2cc76dc10ccd9c60b1e9398917 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 6.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 SMART SM00363 1 57 2.8E-14 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 Gene3D G3DSA:3.30.70.1560 126 205 1.2E-54 T 13-10-2018 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 Pfam PF01479 S4 domain 1 46 4.8E-12 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 Gene3D G3DSA:3.30.70.580 62 227 1.2E-54 T 13-10-2018 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 224 1.4E-47 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 SUPERFAMILY SSF55120 57 228 1.06E-40 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 Gene3D G3DSA:3.10.290.10 1 56 6.8E-21 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 Pfam PF00849 RNA pseudouridylate synthase 61 193 4.4E-19 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 SUPERFAMILY SSF55174 1 56 1.24E-14 T 13-10-2018 CLOST_1824 54dd1e6f834498aa6151198958a46b72 236 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 96 110 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CLOST_0055 816773efc3f724390526d0861cff0f59 435 Pfam PF11799 impB/mucB/samB family C-terminal domain 259 367 1.0E-14 T 13-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CLOST_0055 816773efc3f724390526d0861cff0f59 435 Gene3D G3DSA:3.30.70.270 15 175 1.6E-31 T 13-10-2018 CLOST_0055 816773efc3f724390526d0861cff0f59 435 SUPERFAMILY SSF56672 13 253 1.78E-49 T 13-10-2018 CLOST_0055 816773efc3f724390526d0861cff0f59 435 Gene3D G3DSA:2.30.40.20 32 86 1.6E-31 T 13-10-2018 CLOST_0055 816773efc3f724390526d0861cff0f59 435 SUPERFAMILY SSF100879 263 360 4.32E-7 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CLOST_0055 816773efc3f724390526d0861cff0f59 435 Pfam PF00817 impB/mucB/samB family 18 168 7.9E-30 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CLOST_0055 816773efc3f724390526d0861cff0f59 435 Gene3D G3DSA:1.10.150.20 196 248 2.6E-9 T 13-10-2018 CLOST_0055 816773efc3f724390526d0861cff0f59 435 Gene3D G3DSA:3.30.1490.100 262 369 7.2E-8 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CLOST_2173 0da698a98bfaba901ddcececfdf6f7d0 122 Gene3D G3DSA:1.10.8.50 1 71 2.7E-30 T 13-10-2018 CLOST_2173 0da698a98bfaba901ddcececfdf6f7d0 122 PIRSF PIRSF002134 1 122 6.6E-43 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2173 0da698a98bfaba901ddcececfdf6f7d0 122 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 6.0E-52 T 13-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2173 0da698a98bfaba901ddcececfdf6f7d0 122 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 13-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2173 0da698a98bfaba901ddcececfdf6f7d0 122 SUPERFAMILY SSF46946 2 114 6.02E-46 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CLOST_2173 0da698a98bfaba901ddcececfdf6f7d0 122 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.6E-32 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2173 0da698a98bfaba901ddcececfdf6f7d0 122 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.828 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2173 0da698a98bfaba901ddcececfdf6f7d0 122 Gene3D G3DSA:4.10.910.10 72 122 1.1E-24 T 13-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1018 af89886f7c354bc64023de4167f1c99d 230 Gene3D G3DSA:1.10.10.10 127 228 2.0E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1018 af89886f7c354bc64023de4167f1c99d 230 SUPERFAMILY SSF52172 3 180 2.56E-42 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1018 af89886f7c354bc64023de4167f1c99d 230 Gene3D G3DSA:3.40.50.2300 1 126 8.0E-39 T 13-10-2018 CLOST_1018 af89886f7c354bc64023de4167f1c99d 230 SMART SM00448 3 113 6.7E-45 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1018 af89886f7c354bc64023de4167f1c99d 230 SMART SM00862 148 224 3.0E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1018 af89886f7c354bc64023de4167f1c99d 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 7.1E-22 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1018 af89886f7c354bc64023de4167f1c99d 230 Pfam PF00072 Response regulator receiver domain 5 113 3.5E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2159 61bf9a9d7a5cf0950e8931dab6293bb7 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 86 8.4E-15 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CLOST_2159 61bf9a9d7a5cf0950e8931dab6293bb7 87 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 86 3.8E-15 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CLOST_2159 61bf9a9d7a5cf0950e8931dab6293bb7 87 Gene3D G3DSA:3.30.2310.20 1 87 5.9E-30 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily CLOST_2159 61bf9a9d7a5cf0950e8931dab6293bb7 87 SUPERFAMILY SSF143011 1 85 4.97E-25 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily CLOST_0500 4b3e1fa6418fd0d4d5e95a6348718dfd 363 Pfam PF13487 HD domain 191 249 1.2E-11 T 13-10-2018 CLOST_0500 4b3e1fa6418fd0d4d5e95a6348718dfd 363 SUPERFAMILY SSF109604 140 298 9.42E-26 T 13-10-2018 CLOST_0500 4b3e1fa6418fd0d4d5e95a6348718dfd 363 SMART SM00471 132 268 0.0025 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0500 4b3e1fa6418fd0d4d5e95a6348718dfd 363 Gene3D G3DSA:1.10.3210.10 3 300 3.3E-60 T 13-10-2018 CLOST_1990 270824875941d71d7d4669c32f68af35 269 SUPERFAMILY SSF51569 4 263 1.37E-96 T 13-10-2018 CLOST_1990 270824875941d71d7d4669c32f68af35 269 Pfam PF00793 DAHP synthetase I family 19 261 5.0E-77 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CLOST_1990 270824875941d71d7d4669c32f68af35 269 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 5 259 6.3E-119 T 13-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CLOST_1990 270824875941d71d7d4669c32f68af35 269 Gene3D G3DSA:3.20.20.70 4 262 5.3E-100 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1225 922d09c2c1792f0c81642a9342239fa3 142 Gene3D G3DSA:3.40.630.30 10 137 2.4E-19 T 13-10-2018 CLOST_1225 922d09c2c1792f0c81642a9342239fa3 142 SUPERFAMILY SSF55729 21 131 2.62E-19 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1225 922d09c2c1792f0c81642a9342239fa3 142 Pfam PF00583 Acetyltransferase (GNAT) family 26 127 1.5E-12 T 13-10-2018 IPR000182 GNAT domain CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00691 Adhesin B signature 65 83 3.8E-16 T 13-10-2018 IPR006129 Adhesin B GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00691 Adhesin B signature 84 103 3.8E-16 T 13-10-2018 IPR006129 Adhesin B GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00691 Adhesin B signature 200 217 3.8E-16 T 13-10-2018 IPR006129 Adhesin B GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00691 Adhesin B signature 144 163 3.8E-16 T 13-10-2018 IPR006129 Adhesin B GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00691 Adhesin B signature 293 311 3.8E-16 T 13-10-2018 IPR006129 Adhesin B GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00691 Adhesin B signature 249 266 3.8E-16 T 13-10-2018 IPR006129 Adhesin B GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00691 Adhesin B signature 40 61 3.8E-16 T 13-10-2018 IPR006129 Adhesin B GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 Gene3D G3DSA:3.40.50.1980 29 201 5.0E-50 T 13-10-2018 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 Gene3D G3DSA:3.40.50.1980 203 315 9.5E-37 T 13-10-2018 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 311 8.0E-70 T 13-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 SUPERFAMILY SSF53807 16 311 1.91E-73 T 13-10-2018 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00690 Adhesin family signature 40 58 1.7E-14 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00690 Adhesin family signature 71 84 1.7E-14 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00690 Adhesin family signature 84 101 1.7E-14 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00690 Adhesin family signature 200 221 1.7E-14 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 CLOST_1669 f6a09c617eb9fd037bccfce369af770e 315 PRINTS PR00690 Adhesin family signature 253 271 1.7E-14 T 13-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 406 417 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 129 274 6.6E-54 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 Pfam PF12838 4Fe-4S dicluster domain 367 418 8.9E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 SUPERFAMILY SSF142019 85 294 3.01E-60 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 SUPERFAMILY SSF46548 325 437 4.45E-17 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 103 1.3E-37 T 13-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 Gene3D G3DSA:1.10.1060.10 356 434 5.4E-9 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 Gene3D G3DSA:3.40.50.11540 134 283 2.9E-14 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 Hamap MF_00461 Ion-translocating oxidoreductase complex subunit C [rsxC]. 1 442 154.386 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 4 436 1.4E-168 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 CLOST_1402 0d79fa061c3d66995be1e6c04245c824 442 Pfam PF10531 SLBB domain 289 336 8.4E-12 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0541 8b1f1de461d9218d521e5932f3e9602d 358 Gene3D G3DSA:3.40.50.2300 155 349 1.2E-95 T 13-10-2018 CLOST_0541 8b1f1de461d9218d521e5932f3e9602d 358 Gene3D G3DSA:3.40.50.2300 54 329 1.2E-95 T 13-10-2018 CLOST_0541 8b1f1de461d9218d521e5932f3e9602d 358 SUPERFAMILY SSF53822 53 341 5.44E-64 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_0541 8b1f1de461d9218d521e5932f3e9602d 358 Pfam PF13407 Periplasmic binding protein domain 55 310 5.9E-52 T 13-10-2018 IPR025997 Periplasmic binding protein CLOST_0512 851febc84b23b30c7c1b46cfedffae86 376 SUPERFAMILY SSF52283 3 177 1.53E-33 T 13-10-2018 CLOST_0512 851febc84b23b30c7c1b46cfedffae86 376 SUPERFAMILY SSF51735 157 268 2.23E-5 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0512 851febc84b23b30c7c1b46cfedffae86 376 Gene3D G3DSA:3.40.50.720 1 133 6.8E-20 T 13-10-2018 CLOST_0512 851febc84b23b30c7c1b46cfedffae86 376 Gene3D G3DSA:3.40.50.720 139 300 6.5E-6 T 13-10-2018 CLOST_0512 851febc84b23b30c7c1b46cfedffae86 376 SMART SM01003 5 122 3.7E-5 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CLOST_0512 851febc84b23b30c7c1b46cfedffae86 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 163 351 5.4E-6 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CLOST_0512 851febc84b23b30c7c1b46cfedffae86 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 14 125 6.5E-15 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 Pfam PF00248 Aldo/keto reductase family 15 216 4.3E-23 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 Gene3D G3DSA:3.30.70.20 256 315 7.8E-11 T 13-10-2018 CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 SUPERFAMILY SSF51430 1 247 2.36E-42 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 PRINTS PR00069 Aldo-keto reductase signature 128 145 9.2E-9 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 PRINTS PR00069 Aldo-keto reductase signature 94 112 9.2E-9 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 PRINTS PR00069 Aldo-keto reductase signature 42 66 9.2E-9 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 Pfam PF00037 4Fe-4S binding domain 264 285 8.9E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 SUPERFAMILY SSF54862 256 315 3.53E-14 T 13-10-2018 CLOST_1488 4bc5e05c498c919865879cb8903a49b2 316 Gene3D G3DSA:3.20.20.100 1 247 8.3E-41 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily CLOST_2460 2e6eb6eff42fd63061551835ec410a8c 335 Pfam PF01522 Polysaccharide deacetylase 46 163 4.6E-30 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOST_2460 2e6eb6eff42fd63061551835ec410a8c 335 SUPERFAMILY SSF88713 35 233 1.13E-57 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CLOST_2460 2e6eb6eff42fd63061551835ec410a8c 335 Gene3D G3DSA:3.20.20.370 25 237 4.8E-68 T 13-10-2018 CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 Gene3D G3DSA:1.10.10.10 1 91 1.4E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 9.8E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 SUPERFAMILY SSF46785 1 87 7.4E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 SUPERFAMILY SSF53850 92 293 2.48E-24 T 13-10-2018 CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 Pfam PF03466 LysR substrate binding domain 91 291 9.9E-27 T 13-10-2018 IPR005119 LysR, substrate-binding CLOST_1434 28249911e4e70f7788f3ca57ee13adde 298 Gene3D G3DSA:3.40.190.290 92 296 1.2E-23 T 13-10-2018 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 Pfam PF08529 NusA N-terminal domain 4 127 1.2E-42 T 13-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 SUPERFAMILY SSF50249 135 210 1.61E-13 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 Gene3D G3DSA:2.40.50.140 139 209 4.9E-19 T 13-10-2018 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 Pfam PF13184 NusA-like KH domain 241 308 9.7E-28 T 13-10-2018 IPR025249 KH domain, NusA-like GO:0003723 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 357 29.623 T 13-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 354 2.4E-126 T 13-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 SUPERFAMILY SSF54814 290 353 4.8E-16 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 Gene3D G3DSA:3.30.300.20 210 288 2.0E-33 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 SUPERFAMILY SSF69705 1 129 1.01E-36 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 SUPERFAMILY SSF54814 211 289 1.77E-30 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 Gene3D G3DSA:3.30.300.20 289 357 2.6E-31 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta CLOST_1693 fa57402ed95c84aaa6e9baa5cadbaa95 357 Gene3D G3DSA:3.30.1480.10 1 131 1.2E-44 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 CLOST_0352 a0f5969f24a400e360c49bad3d87ca2f 706 Gene3D G3DSA:3.30.457.10 610 687 1.6E-12 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0352 a0f5969f24a400e360c49bad3d87ca2f 706 Pfam PF07833 Copper amine oxidase N-terminal domain 576 632 4.3E-8 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0352 a0f5969f24a400e360c49bad3d87ca2f 706 Pfam PF07833 Copper amine oxidase N-terminal domain 606 700 2.3E-18 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0352 a0f5969f24a400e360c49bad3d87ca2f 706 SUPERFAMILY SSF55383 608 686 5.49E-18 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_1157 9d10699aabf9752f184a473a855f33b7 356 SUPERFAMILY SSF52518 1 200 6.22E-62 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1157 9d10699aabf9752f184a473a855f33b7 356 Gene3D G3DSA:3.40.50.920 234 347 5.7E-22 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1157 9d10699aabf9752f184a473a855f33b7 356 SUPERFAMILY SSF52922 238 344 2.51E-21 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1157 9d10699aabf9752f184a473a855f33b7 356 Gene3D G3DSA:3.40.50.970 1 188 5.6E-66 T 13-10-2018 CLOST_1157 9d10699aabf9752f184a473a855f33b7 356 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 246 336 1.6E-21 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CLOST_1157 9d10699aabf9752f184a473a855f33b7 356 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 239 4.5E-53 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CLOST_1182 b7e3e8e66c661ddce718be2811f2a3a0 100 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 97 1.1E-21 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 CLOST_1182 b7e3e8e66c661ddce718be2811f2a3a0 100 Pfam PF03334 Na+/H+ antiporter subunit 10 89 5.9E-20 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 CLOST_2567 f8ab922e4ea74a2dd95b3a04c932b970 316 Pfam PF09991 Predicted membrane protein (DUF2232) 26 306 2.5E-48 T 13-10-2018 IPR018710 Protein of unknown function DUF2232 CLOST_2268 380cd9dc30f2595ec57373b33c9cb9b8 300 SUPERFAMILY SSF161098 89 274 1.6E-16 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2268 380cd9dc30f2595ec57373b33c9cb9b8 300 Gene3D G3DSA:1.10.3720.10 86 292 4.3E-12 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2268 380cd9dc30f2595ec57373b33c9cb9b8 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 285 3.6E-11 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_2274 dbc42cd211ba2770dc243dd5651bef73 150 Pfam PF02001 Protein of unknown function DUF134 3 95 9.2E-21 T 13-10-2018 IPR002852 Uncharacterised protein family UPF0251 CLOST_2274 dbc42cd211ba2770dc243dd5651bef73 150 SUPERFAMILY SSF88659 39 78 1.14E-5 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_2274 dbc42cd211ba2770dc243dd5651bef73 150 Gene3D G3DSA:1.10.10.10 36 83 9.5E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2274 dbc42cd211ba2770dc243dd5651bef73 150 Hamap MF_00674 UPF0251 protein . 2 98 25.662 T 13-10-2018 IPR002852 Uncharacterised protein family UPF0251 CLOST_2242 1fee03420c9989a7793e8395df2713c5 191 PIRSF PIRSF000441 13 191 9.2E-78 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 CLOST_2242 1fee03420c9989a7793e8395df2713c5 191 Gene3D G3DSA:1.10.3130.10 6 80 1.4E-21 T 13-10-2018 CLOST_2242 1fee03420c9989a7793e8395df2713c5 191 Gene3D G3DSA:2.160.10.10 81 190 3.1E-36 T 13-10-2018 CLOST_2242 1fee03420c9989a7793e8395df2713c5 191 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 19 180 1.2E-71 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 CLOST_2242 1fee03420c9989a7793e8395df2713c5 191 SUPERFAMILY SSF51161 10 184 1.03E-54 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_2242 1fee03420c9989a7793e8395df2713c5 191 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 7.4E-8 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 SUPERFAMILY SSF58104 361 691 7.72E-64 T 13-10-2018 CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 Pfam PF02743 Cache domain 61 294 1.1E-23 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 490 643 4.3E-34 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 SMART SM00283 395 691 2.0E-54 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 SUPERFAMILY SSF103190 133 213 9.68E-9 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 Gene3D G3DSA:3.30.450.20 62 300 2.8E-50 T 13-10-2018 CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 Gene3D G3DSA:1.10.287.950 389 691 1.8E-60 T 13-10-2018 CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 Gene3D G3DSA:3.30.450.20 71 204 2.8E-50 T 13-10-2018 CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 SMART SM00304 332 387 4.9E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0031 c45352b66b323333e4406dfaf53fe8dc 693 Gene3D G3DSA:1.20.1480.50 301 388 7.5E-9 T 13-10-2018 CLOST_2307 de3d3df6f541a312de30453ce49e5c3c 95 SUPERFAMILY SSF160544 9 86 3.79E-19 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CLOST_2307 de3d3df6f541a312de30453ce49e5c3c 95 Pfam PF01312 FlhB HrpN YscU SpaS Family 11 82 2.7E-16 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_2307 de3d3df6f541a312de30453ce49e5c3c 95 Gene3D G3DSA:3.40.1690.10 8 90 7.1E-21 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 SUPERFAMILY SSF54373 218 311 4.71E-5 T 13-10-2018 CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 Gene3D G3DSA:3.50.50.60 3 348 8.9E-125 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 Pfam PF04324 BFD-like [2Fe-2S] binding domain 398 451 2.7E-17 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 Pfam PF01266 FAD dependent oxidoreductase 3 353 7.0E-60 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 Gene3D G3DSA:3.30.9.10 86 314 8.9E-125 T 13-10-2018 CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 SUPERFAMILY SSF51905 1 404 3.8E-47 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 5.8E-5 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 5.8E-5 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 261 5.8E-5 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 67 77 5.8E-5 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1951 424da769f38ab3ff8e5d48c18638d0c1 480 Gene3D G3DSA:1.10.10.1100 383 461 1.6E-23 T 13-10-2018 CLOST_0534 94f987cfa6bccba2a84b72b29d797285 293 SUPERFAMILY SSF103481 188 280 1.96E-14 T 13-10-2018 CLOST_0534 94f987cfa6bccba2a84b72b29d797285 293 Pfam PF00892 EamA-like transporter family 6 136 1.2E-14 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_0534 94f987cfa6bccba2a84b72b29d797285 293 Pfam PF00892 EamA-like transporter family 146 279 9.3E-18 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_0534 94f987cfa6bccba2a84b72b29d797285 293 SUPERFAMILY SSF103481 40 139 8.37E-11 T 13-10-2018 CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 Pfam PF00266 Aminotransferase class-V 6 369 8.7E-92 T 13-10-2018 IPR000192 Aminotransferase class V domain CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 PIRSF PIRSF005572 3 384 2.6E-134 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 215 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 Gene3D G3DSA:3.90.1150.10 6 373 2.2E-158 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 Gene3D G3DSA:3.40.640.10 63 238 2.2E-158 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 Gene3D G3DSA:1.10.260.50 17 282 2.2E-158 T 13-10-2018 CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 SUPERFAMILY SSF53383 5 379 2.15E-112 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 6 386 5.4E-188 T 13-10-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 CLOST_1494 1f8d8680e220ece321aa7ca8f0708ea8 398 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 395 52.806 T 13-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 SUPERFAMILY SSF53850 27 343 1.63E-93 T 13-10-2018 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 75 89 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 48 69 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 32 48 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 147 161 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 91 104 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 246 265 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 165 184 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 291 317 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 122 138 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 202 221 2.7E-51 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 Pfam PF13416 Bacterial extracellular solute-binding protein 41 304 7.4E-41 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 Gene3D G3DSA:3.40.190.10 31 313 1.6E-123 T 13-10-2018 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 PIRSF PIRSF019574 1 345 1.5E-128 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1745 36824c7ac886aec267bfcab46aa7800d 345 Gene3D G3DSA:3.40.190.10 131 316 1.6E-123 T 13-10-2018 CLOST_1217 c86ad57346e6891693308c7847593515 788 Gene3D G3DSA:3.40.50.2000 33 788 0.0 T 13-10-2018 CLOST_1217 c86ad57346e6891693308c7847593515 788 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 4 788 0.0 T 13-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CLOST_1217 c86ad57346e6891693308c7847593515 788 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 628 640 - T 13-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CLOST_1217 c86ad57346e6891693308c7847593515 788 PIRSF PIRSF000460 4 788 3.6E-209 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CLOST_1217 c86ad57346e6891693308c7847593515 788 SUPERFAMILY SSF53756 3 788 2.98E-272 T 13-10-2018 CLOST_1217 c86ad57346e6891693308c7847593515 788 Gene3D G3DSA:3.40.50.2000 441 778 0.0 T 13-10-2018 CLOST_1217 c86ad57346e6891693308c7847593515 788 Pfam PF00343 Carbohydrate phosphorylase 89 788 6.2E-296 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CLOST_0710 63da1067a488c33c7febf9660a5c6791 284 Gene3D G3DSA:1.10.285.20 68 136 4.8E-9 T 13-10-2018 CLOST_0710 63da1067a488c33c7febf9660a5c6791 284 SUPERFAMILY SSF111321 1 280 1.31E-72 T 13-10-2018 IPR036075 AF1104-like superfamily CLOST_0710 63da1067a488c33c7febf9660a5c6791 284 Pfam PF01937 Protein of unknown function DUF89 4 273 1.5E-43 T 13-10-2018 IPR002791 Domain of unknown function DUF89 CLOST_0710 63da1067a488c33c7febf9660a5c6791 284 Gene3D G3DSA:3.40.50.10880 137 284 6.6E-54 T 13-10-2018 CLOST_0710 63da1067a488c33c7febf9660a5c6791 284 PIRSF PIRSF006593 1 283 9.4E-83 T 13-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 CLOST_2510 1fea3b73f35a189df6beb351b6780b20 186 Pfam PF00583 Acetyltransferase (GNAT) family 63 170 2.4E-10 T 13-10-2018 IPR000182 GNAT domain CLOST_2510 1fea3b73f35a189df6beb351b6780b20 186 SUPERFAMILY SSF55729 27 179 7.89E-16 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2510 1fea3b73f35a189df6beb351b6780b20 186 Gene3D G3DSA:3.40.630.30 38 179 4.1E-17 T 13-10-2018 CLOST_0614 59daf7ed1788c54634d3b7e7c4aae215 259 Pfam PF00005 ABC transporter 28 184 1.9E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0614 59daf7ed1788c54634d3b7e7c4aae215 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 13 259 9.2E-124 T 13-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CLOST_0614 59daf7ed1788c54634d3b7e7c4aae215 259 Gene3D G3DSA:3.40.50.300 13 255 8.8E-62 T 13-10-2018 CLOST_0614 59daf7ed1788c54634d3b7e7c4aae215 259 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0614 59daf7ed1788c54634d3b7e7c4aae215 259 SMART SM00382 37 230 1.3E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0614 59daf7ed1788c54634d3b7e7c4aae215 259 SUPERFAMILY SSF52540 7 245 1.77E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1602 58400c76e501947ea6900348bd52b936 225 Gene3D G3DSA:3.40.50.2300 1 124 3.7E-40 T 13-10-2018 CLOST_1602 58400c76e501947ea6900348bd52b936 225 Gene3D G3DSA:1.10.10.10 125 223 1.5E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1602 58400c76e501947ea6900348bd52b936 225 SMART SM00448 1 112 3.5E-44 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1602 58400c76e501947ea6900348bd52b936 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 1.7E-18 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1602 58400c76e501947ea6900348bd52b936 225 SUPERFAMILY SSF52172 1 178 8.97E-42 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1602 58400c76e501947ea6900348bd52b936 225 Pfam PF00072 Response regulator receiver domain 3 113 6.5E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1602 58400c76e501947ea6900348bd52b936 225 SMART SM00862 145 220 8.3E-15 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1574 4b13693ce5847f1b524ab39472b89ebf 328 SUPERFAMILY SSF52540 52 232 2.49E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1574 4b13693ce5847f1b524ab39472b89ebf 328 PIRSF PIRSF006230 42 328 5.5E-98 T 13-10-2018 IPR016478 GTPase, MTG1 CLOST_1574 4b13693ce5847f1b524ab39472b89ebf 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 212 227 6.7E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1574 4b13693ce5847f1b524ab39472b89ebf 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 166 186 6.7E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1574 4b13693ce5847f1b524ab39472b89ebf 328 Gene3D G3DSA:1.10.1580.10 223 326 3.6E-26 T 13-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily CLOST_1574 4b13693ce5847f1b524ab39472b89ebf 328 Gene3D G3DSA:3.40.50.300 46 220 2.3E-47 T 13-10-2018 CLOST_1574 4b13693ce5847f1b524ab39472b89ebf 328 Pfam PF01926 50S ribosome-binding GTPase 165 242 1.4E-16 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1574 4b13693ce5847f1b524ab39472b89ebf 328 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 46 323 2.7E-103 T 13-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis CLOST_0876 dc941d1b3d43ab6698336aaf82e53a18 562 Gene3D G3DSA:3.40.449.10 99 233 5.7E-17 T 13-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CLOST_0876 dc941d1b3d43ab6698336aaf82e53a18 562 Gene3D G3DSA:2.170.8.10 301 357 5.7E-17 T 13-10-2018 CLOST_0876 dc941d1b3d43ab6698336aaf82e53a18 562 SUPERFAMILY SSF68923 53 232 2.44E-24 T 13-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CLOST_0876 dc941d1b3d43ab6698336aaf82e53a18 562 SUPERFAMILY SSF53795 235 542 2.98E-66 T 13-10-2018 CLOST_0876 dc941d1b3d43ab6698336aaf82e53a18 562 Gene3D G3DSA:3.90.228.20 234 494 5.7E-17 T 13-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CLOST_0876 dc941d1b3d43ab6698336aaf82e53a18 562 Pfam PF01293 Phosphoenolpyruvate carboxykinase 99 493 1.4E-22 T 13-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CLOST_0955 be39cf888933c72e476bb20a4f3842e9 506 Gene3D G3DSA:3.40.50.880 251 461 4.7E-19 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0955 be39cf888933c72e476bb20a4f3842e9 506 SUPERFAMILY SSF52317 255 458 5.47E-35 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0955 be39cf888933c72e476bb20a4f3842e9 506 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 497 7.0E-159 T 13-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CLOST_0955 be39cf888933c72e476bb20a4f3842e9 506 SUPERFAMILY SSF52540 1 229 9.69E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0955 be39cf888933c72e476bb20a4f3842e9 506 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 505 166.779 T 13-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CLOST_0955 be39cf888933c72e476bb20a4f3842e9 506 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 449 1.1E-54 T 13-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CLOST_0955 be39cf888933c72e476bb20a4f3842e9 506 Gene3D G3DSA:3.40.50.300 1 245 2.7E-55 T 13-10-2018 CLOST_0955 be39cf888933c72e476bb20a4f3842e9 506 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 230 5.8E-20 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOST_1976 45813ee47778243eb76189975309a82e 116 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 56 103 3.8E-5 T 13-10-2018 IPR008792 Coenzyme PQQ synthesis D CLOST_1944 6229ea36a2e2efac56aa7aa083124dbe 1594 Gene3D G3DSA:3.40.50.620 899 1101 3.0E-25 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1944 6229ea36a2e2efac56aa7aa083124dbe 1594 SUPERFAMILY SSF109604 169 275 8.17E-9 T 13-10-2018 CLOST_1944 6229ea36a2e2efac56aa7aa083124dbe 1594 SUPERFAMILY SSF48371 392 835 1.94E-7 T 13-10-2018 IPR016024 Armadillo-type fold CLOST_1944 6229ea36a2e2efac56aa7aa083124dbe 1594 Pfam PF01467 Cytidylyltransferase-like 906 1066 1.1E-5 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CLOST_1944 6229ea36a2e2efac56aa7aa083124dbe 1594 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 904 949 1.3E-7 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CLOST_1944 6229ea36a2e2efac56aa7aa083124dbe 1594 SUPERFAMILY SSF52374 902 1098 3.75E-24 T 13-10-2018 CLOST_0863 70e5c45c28106a87a52180d6cca30dfb 108 SUPERFAMILY SSF89360 2 83 3.34E-13 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 CLOST_0863 70e5c45c28106a87a52180d6cca30dfb 108 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 83 1.3E-6 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CLOST_0863 70e5c45c28106a87a52180d6cca30dfb 108 Gene3D G3DSA:2.60.300.12 1 97 1.7E-11 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 CLOST_0004 2068457aa6ef649319a8b34e7d1aee02 361 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 13-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CLOST_0004 2068457aa6ef649319a8b34e7d1aee02 361 SUPERFAMILY SSF52540 1 340 1.97E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0004 2068457aa6ef649319a8b34e7d1aee02 361 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 351 5.6E-19 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal CLOST_0004 2068457aa6ef649319a8b34e7d1aee02 361 Gene3D G3DSA:1.20.1050.90 120 306 3.1E-105 T 13-10-2018 CLOST_0004 2068457aa6ef649319a8b34e7d1aee02 361 ProSitePatterns PS00618 RecF protein signature 2. 307 325 - T 13-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CLOST_0004 2068457aa6ef649319a8b34e7d1aee02 361 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 346 4.9E-100 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CLOST_0004 2068457aa6ef649319a8b34e7d1aee02 361 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 361 87.907 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CLOST_0004 2068457aa6ef649319a8b34e7d1aee02 361 Gene3D G3DSA:3.40.50.300 6 340 3.1E-105 T 13-10-2018 CLOST_1213 855e227ff4bdd00d00d1928d1c0e1310 278 SUPERFAMILY SSF161098 7 278 1.21E-59 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1213 855e227ff4bdd00d00d1928d1c0e1310 278 Gene3D G3DSA:1.10.3720.10 2 269 1.1E-50 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1213 855e227ff4bdd00d00d1928d1c0e1310 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 271 2.7E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 SMART SM00387 279 391 9.1E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 SMART SM00304 115 168 1.3E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 SUPERFAMILY SSF47384 152 234 6.28E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 SUPERFAMILY SSF55874 226 387 3.01E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 Gene3D G3DSA:3.30.565.10 240 393 4.6E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 330 3.5E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 388 3.5E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 334 344 3.5E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 369 3.5E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 280 387 5.4E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 SUPERFAMILY SSF158472 117 164 4.45E-7 T 13-10-2018 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 Pfam PF00512 His Kinase A (phospho-acceptor) domain 170 234 3.3E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 Gene3D G3DSA:1.10.287.130 119 238 3.6E-31 T 13-10-2018 CLOST_2261 2d5931a6b92c1461e7b6c63af568414f 393 SMART SM00388 169 236 5.6E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_2130 64c447240ddaf391b3a7f8e61d8eecc0 158 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 142 2.8E-30 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I CLOST_2130 64c447240ddaf391b3a7f8e61d8eecc0 158 SUPERFAMILY SSF52788 1 147 2.09E-34 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily CLOST_2130 64c447240ddaf391b3a7f8e61d8eecc0 158 Gene3D G3DSA:3.40.50.2300 1 152 5.9E-39 T 13-10-2018 CLOST_2130 64c447240ddaf391b3a7f8e61d8eecc0 158 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 118 133 3.2E-9 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CLOST_2130 64c447240ddaf391b3a7f8e61d8eecc0 158 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 3.2E-9 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CLOST_2130 64c447240ddaf391b3a7f8e61d8eecc0 158 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 80 95 3.2E-9 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CLOST_2130 64c447240ddaf391b3a7f8e61d8eecc0 158 SMART SM00226 2 146 4.4E-28 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I CLOST_0977 452974ee78f16168f322398112f7d8e6 144 SMART SM00347 30 127 1.0E-18 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0977 452974ee78f16168f322398112f7d8e6 144 SUPERFAMILY SSF46785 8 140 4.34E-33 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0977 452974ee78f16168f322398112f7d8e6 144 Gene3D G3DSA:1.10.10.10 2 142 4.8E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0977 452974ee78f16168f322398112f7d8e6 144 Pfam PF01047 MarR family 37 93 3.2E-14 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0977 452974ee78f16168f322398112f7d8e6 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.8E-6 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0977 452974ee78f16168f322398112f7d8e6 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 1.8E-6 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0977 452974ee78f16168f322398112f7d8e6 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 1.8E-6 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0367 75fde70758e02676e8f9a0c1cb832907 331 Pfam PF08666 SAF domain 279 329 4.6E-8 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CLOST_0367 75fde70758e02676e8f9a0c1cb832907 331 TIGRFAM TIGR03569 NeuB_NnaB: N-acetylneuraminate synthase 4 329 6.7E-159 T 13-10-2018 IPR020007 N-acetylneuraminate synthase KEGG: 00520+2.5.1.101|MetaCyc: PWY-6749|MetaCyc: PWY-7131 CLOST_0367 75fde70758e02676e8f9a0c1cb832907 331 Gene3D G3DSA:3.20.20.70 1 261 6.4E-112 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0367 75fde70758e02676e8f9a0c1cb832907 331 SMART SM00858 277 331 0.0013 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CLOST_0367 75fde70758e02676e8f9a0c1cb832907 331 SUPERFAMILY SSF51569 2 287 7.69E-100 T 13-10-2018 CLOST_0367 75fde70758e02676e8f9a0c1cb832907 331 Gene3D G3DSA:3.90.1210.10 266 331 8.9E-23 T 13-10-2018 CLOST_0367 75fde70758e02676e8f9a0c1cb832907 331 Pfam PF03102 NeuB family 23 263 1.7E-107 T 13-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 CLOST_0367 75fde70758e02676e8f9a0c1cb832907 331 SUPERFAMILY SSF51269 269 329 3.66E-19 T 13-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 CLOST_0903 0ef59e2eaba60dde45749c7cc0a0789c 488 Gene3D G3DSA:3.40.605.10 33 449 4.3E-141 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 CLOST_0903 0ef59e2eaba60dde45749c7cc0a0789c 488 Gene3D G3DSA:3.40.309.10 237 435 4.3E-141 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 CLOST_0903 0ef59e2eaba60dde45749c7cc0a0789c 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 232 239 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 CLOST_0903 0ef59e2eaba60dde45749c7cc0a0789c 488 PIRSF PIRSF036492 9 487 1.6E-110 T 13-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 CLOST_0903 0ef59e2eaba60dde45749c7cc0a0789c 488 SUPERFAMILY SSF53720 2 452 3.27E-130 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 CLOST_0903 0ef59e2eaba60dde45749c7cc0a0789c 488 Pfam PF00171 Aldehyde dehydrogenase family 2 451 1.7E-130 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 Pfam PF00005 ABC transporter 280 436 4.9E-18 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 Gene3D G3DSA:3.40.50.300 249 505 1.1E-41 T 13-10-2018 CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 SMART SM00382 289 487 0.037 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 SMART SM00382 30 220 1.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 SUPERFAMILY SSF52540 4 228 8.77E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 Pfam PF00005 ABC transporter 21 172 2.9E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 SUPERFAMILY SSF52540 253 494 6.45E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0543 4ec3988d17c09c0ed2f6b3c1a2f97850 506 Gene3D G3DSA:3.40.50.300 2 238 1.6E-53 T 13-10-2018 CLOST_1426 7b5d966f3d0f9ad1071d8042441d66db 240 Pfam PF00005 ABC transporter 21 161 7.4E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1426 7b5d966f3d0f9ad1071d8042441d66db 240 Gene3D G3DSA:3.40.50.300 2 214 2.1E-60 T 13-10-2018 CLOST_1426 7b5d966f3d0f9ad1071d8042441d66db 240 SMART SM00382 29 209 4.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1426 7b5d966f3d0f9ad1071d8042441d66db 240 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1426 7b5d966f3d0f9ad1071d8042441d66db 240 SUPERFAMILY SSF52540 4 211 4.51E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1104 1577e8a66d239dccce49c477eb720f18 272 ProSitePatterns PS01229 Hypothetical cof family signature 2. 221 243 - T 13-10-2018 CLOST_1104 1577e8a66d239dccce49c477eb720f18 272 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 13-10-2018 CLOST_1104 1577e8a66d239dccce49c477eb720f18 272 Gene3D G3DSA:3.30.1240.10 83 196 8.7E-76 T 13-10-2018 CLOST_1104 1577e8a66d239dccce49c477eb720f18 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 267 9.3E-64 T 13-10-2018 IPR000150 Cof family GO:0016787 CLOST_1104 1577e8a66d239dccce49c477eb720f18 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 267 5.5E-68 T 13-10-2018 CLOST_1104 1577e8a66d239dccce49c477eb720f18 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 240 3.2E-25 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CLOST_1104 1577e8a66d239dccce49c477eb720f18 272 Gene3D G3DSA:3.40.50.1000 3 267 8.7E-76 T 13-10-2018 IPR023214 HAD superfamily CLOST_1104 1577e8a66d239dccce49c477eb720f18 272 SUPERFAMILY SSF56784 1 271 3.71E-69 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 140 411 60.894 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 Gene3D G3DSA:3.40.50.300 210 399 3.9E-113 T 13-10-2018 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 SMART SM00382 209 389 8.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 Pfam PF00448 SRP54-type protein, GTPase domain 211 410 1.2E-77 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 Gene3D G3DSA:1.20.120.140 113 409 3.9E-113 T 13-10-2018 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 SMART SM00962 210 411 7.2E-116 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 SUPERFAMILY SSF52540 207 411 1.56E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 Pfam PF02881 SRP54-type protein, helical bundle domain 127 189 2.6E-11 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 141 410 2.6E-108 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 384 397 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 SUPERFAMILY SSF47364 111 190 5.36E-21 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 CLOST_1582 63f58dceb9c8def84bf4ccbf0449ce7e 413 SMART SM00963 116 197 1.1E-15 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_2262 322134b68d5454b1ba9de5a8a6090651 231 Gene3D G3DSA:1.10.10.10 129 229 1.5E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2262 322134b68d5454b1ba9de5a8a6090651 231 Gene3D G3DSA:3.40.50.2300 3 128 1.7E-35 T 13-10-2018 CLOST_2262 322134b68d5454b1ba9de5a8a6090651 231 Pfam PF00072 Response regulator receiver domain 6 115 4.4E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2262 322134b68d5454b1ba9de5a8a6090651 231 SUPERFAMILY SSF52172 3 130 1.1E-39 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_2262 322134b68d5454b1ba9de5a8a6090651 231 SMART SM00862 153 228 5.5E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_2262 322134b68d5454b1ba9de5a8a6090651 231 SMART SM00448 4 114 1.2E-41 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2262 322134b68d5454b1ba9de5a8a6090651 231 SUPERFAMILY SSF46894 128 228 8.5E-31 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_2262 322134b68d5454b1ba9de5a8a6090651 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 228 1.3E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1992 d38565ea7565f96cc48b2959b6859f35 262 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 260 32.164 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CLOST_1992 d38565ea7565f96cc48b2959b6859f35 262 Gene3D G3DSA:3.20.20.70 1 261 5.1E-95 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1992 d38565ea7565f96cc48b2959b6859f35 262 SUPERFAMILY SSF51366 15 256 4.33E-79 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CLOST_1992 d38565ea7565f96cc48b2959b6859f35 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 54 72 - T 13-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CLOST_1992 d38565ea7565f96cc48b2959b6859f35 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 255 3.3E-85 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CLOST_1118 a255f4c1b9e0ac6bd5bad290724770a7 191 Gene3D G3DSA:3.40.50.300 9 191 2.6E-43 T 13-10-2018 CLOST_1118 a255f4c1b9e0ac6bd5bad290724770a7 191 Pfam PF00005 ABC transporter 31 180 4.3E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1118 a255f4c1b9e0ac6bd5bad290724770a7 191 SUPERFAMILY SSF52540 14 190 6.84E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0993 dce127d63bab35180bccccba834e9aae 366 Pfam PF01890 Cobalamin synthesis G C-terminus 236 355 1.9E-29 T 13-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CLOST_0993 dce127d63bab35180bccccba834e9aae 366 Gene3D G3DSA:3.30.420.180 226 364 7.8E-29 T 13-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 CLOST_0993 dce127d63bab35180bccccba834e9aae 366 Pfam PF11760 Cobalamin synthesis G N-terminal 53 132 2.1E-32 T 13-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CLOST_0993 dce127d63bab35180bccccba834e9aae 366 SUPERFAMILY SSF159664 231 358 5.62E-31 T 13-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 CLOST_0993 dce127d63bab35180bccccba834e9aae 366 SUPERFAMILY SSF159672 1 243 2.22E-50 T 13-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CLOST_0993 dce127d63bab35180bccccba834e9aae 366 Gene3D G3DSA:3.40.50.11220 2 127 1.1E-30 T 13-10-2018 CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 13-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 171 4.4E-43 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 SUPERFAMILY SSF51306 29 176 1.46E-43 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 Gene3D G3DSA:2.10.109.10 37 169 4.4E-32 T 13-10-2018 CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 Pfam PF00717 Peptidase S24-like 35 107 3.2E-13 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 ProSitePatterns PS00760 Signal peptidases I lysine active site. 86 98 - T 13-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 9.4E-18 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 84 96 9.4E-18 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOST_1093 f902eb8b53f300c4be84d2d39ef66bfb 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 128 147 9.4E-18 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CLOST_1874 c0c3098c0718cad801ea8d6726cf6374 135 SUPERFAMILY SSF52788 1 126 1.23E-36 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily CLOST_1874 c0c3098c0718cad801ea8d6726cf6374 135 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 124 2.4E-23 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I CLOST_1874 c0c3098c0718cad801ea8d6726cf6374 135 Gene3D G3DSA:3.40.50.2300 2 133 5.5E-43 T 13-10-2018 CLOST_1874 c0c3098c0718cad801ea8d6726cf6374 135 SMART SM00226 3 127 3.1E-40 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 PIRSF PIRSF000114 1 330 3.7E-106 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 178 318 6.7E-53 T 13-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 Gene3D G3DSA:1.10.1040.10 187 334 3.4E-52 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 SUPERFAMILY SSF51735 4 176 6.09E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 SUPERFAMILY SSF48179 178 329 6.46E-56 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 1.1E-45 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 131 151 1.1E-45 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 171 195 1.1E-45 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 196 220 1.1E-45 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 236 253 1.1E-45 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 1.1E-45 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 Gene3D G3DSA:3.40.50.720 1 185 5.8E-62 T 13-10-2018 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 320 36.604 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 186 207 - T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_1883 0073257975caae56a627fed6c16fc8d5 341 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 158 1.3E-50 T 13-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 CLOST_0680 a0c43d9df39d5d36b502754fd14fcd4e 85 Gene3D G3DSA:2.40.50.220 1 85 9.2E-26 T 13-10-2018 IPR036677 EutN/Ccml superfamily CLOST_0680 a0c43d9df39d5d36b502754fd14fcd4e 85 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 11 79 1.0E-10 T 13-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CLOST_0680 a0c43d9df39d5d36b502754fd14fcd4e 85 SUPERFAMILY SSF159133 1 80 1.44E-23 T 13-10-2018 IPR036677 EutN/Ccml superfamily CLOST_0680 a0c43d9df39d5d36b502754fd14fcd4e 85 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 79 7.3E-26 T 13-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CLOST_1526 f571e7ba8aba52de6c4526adaed03da4 95 SUPERFAMILY SSF68906 50 92 5.58E-5 T 13-10-2018 IPR036361 SAP domain superfamily CLOST_1021 a85f4acca490adcafeb83e0d6a29fc54 244 Gene3D G3DSA:3.30.1600.10 33 170 1.7E-69 T 13-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily CLOST_1021 a85f4acca490adcafeb83e0d6a29fc54 244 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 8 243 57.09 T 13-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 CLOST_1021 a85f4acca490adcafeb83e0d6a29fc54 244 SUPERFAMILY SSF52467 4 242 5.61E-79 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily CLOST_1021 a85f4acca490adcafeb83e0d6a29fc54 244 Gene3D G3DSA:3.40.50.1220 15 240 1.7E-69 T 13-10-2018 CLOST_1021 a85f4acca490adcafeb83e0d6a29fc54 244 Pfam PF02146 Sir2 family 24 200 3.3E-49 T 13-10-2018 IPR003000 Sirtuin family GO:0070403 CLOST_1311 0f7ab3d4c7b7bb9a1bd2e06e10ad901e 88 PRINTS PR01853 Bacterial YajC preprotein translocase signature 44 62 6.9E-13 T 13-10-2018 IPR003849 Preprotein translocase YajC CLOST_1311 0f7ab3d4c7b7bb9a1bd2e06e10ad901e 88 PRINTS PR01853 Bacterial YajC preprotein translocase signature 6 26 6.9E-13 T 13-10-2018 IPR003849 Preprotein translocase YajC CLOST_1311 0f7ab3d4c7b7bb9a1bd2e06e10ad901e 88 Pfam PF02699 Preprotein translocase subunit 9 85 3.8E-29 T 13-10-2018 IPR003849 Preprotein translocase YajC CLOST_1311 0f7ab3d4c7b7bb9a1bd2e06e10ad901e 88 SMART SM01323 4 87 7.8E-34 T 13-10-2018 IPR003849 Preprotein translocase YajC CLOST_1311 0f7ab3d4c7b7bb9a1bd2e06e10ad901e 88 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 6 86 3.6E-24 T 13-10-2018 IPR003849 Preprotein translocase YajC CLOST_1490 16bdeae36da6b8a81e951a2e900e240f 86 Pfam PF06135 Bacterial protein of unknown function (DUF965) 6 84 8.5E-36 T 13-10-2018 IPR009309 Uncharacterised protein family UPF0297 CLOST_1490 16bdeae36da6b8a81e951a2e900e240f 86 PIRSF PIRSF037258 2 86 6.8E-37 T 13-10-2018 IPR009309 Uncharacterised protein family UPF0297 CLOST_1490 16bdeae36da6b8a81e951a2e900e240f 86 Hamap MF_01507 UPF0297 protein . 2 86 25.384 T 13-10-2018 IPR009309 Uncharacterised protein family UPF0297 CLOST_0224 ffb133cdd86ce94582d4d6a85110e253 1118 Gene3D G3DSA:3.40.50.300 1 138 3.5E-16 T 13-10-2018 CLOST_0224 ffb133cdd86ce94582d4d6a85110e253 1118 Gene3D G3DSA:3.40.50.300 139 264 4.0E-23 T 13-10-2018 CLOST_0224 ffb133cdd86ce94582d4d6a85110e253 1118 SUPERFAMILY SSF52540 287 676 9.43E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0224 ffb133cdd86ce94582d4d6a85110e253 1118 Gene3D G3DSA:3.40.50.300 529 670 1.7E-37 T 13-10-2018 CLOST_0224 ffb133cdd86ce94582d4d6a85110e253 1118 Gene3D G3DSA:3.40.50.300 265 383 9.9E-19 T 13-10-2018 CLOST_0224 ffb133cdd86ce94582d4d6a85110e253 1118 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 2 1115 2.9E-280 T 13-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CLOST_0224 ffb133cdd86ce94582d4d6a85110e253 1118 Pfam PF12705 PD-(D/E)XK nuclease superfamily 756 1087 1.2E-48 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type CLOST_1979 f74e8da1f37287bdf9a3067d272a53ad 395 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 6 389 1.7E-190 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1979 f74e8da1f37287bdf9a3067d272a53ad 395 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 54 377 1.9E-51 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_1979 f74e8da1f37287bdf9a3067d272a53ad 395 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 390 52.495 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1979 f74e8da1f37287bdf9a3067d272a53ad 395 Gene3D G3DSA:3.40.50.1100 9 205 1.6E-187 T 13-10-2018 CLOST_1979 f74e8da1f37287bdf9a3067d272a53ad 395 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 80 94 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1979 f74e8da1f37287bdf9a3067d272a53ad 395 SUPERFAMILY SSF53686 4 387 4.98E-150 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_1979 f74e8da1f37287bdf9a3067d272a53ad 395 PIRSF PIRSF001413 1 395 2.7E-170 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CLOST_1979 f74e8da1f37287bdf9a3067d272a53ad 395 Gene3D G3DSA:3.40.50.1100 53 383 1.6E-187 T 13-10-2018 CLOST_0812 ed9776bbcd47582be9d8dcdd0e4d1208 49 Gene3D G3DSA:3.40.50.150 2 49 4.1E-7 T 13-10-2018 CLOST_0812 ed9776bbcd47582be9d8dcdd0e4d1208 49 SUPERFAMILY SSF53335 6 47 1.88E-5 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0812 ed9776bbcd47582be9d8dcdd0e4d1208 49 Pfam PF00145 C-5 cytosine-specific DNA methylase 6 43 1.0E-4 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_1352 005dc9aa737cfebe6381d687066c2961 58 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 1.1E-25 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1352 005dc9aa737cfebe6381d687066c2961 58 Pfam PF01783 Ribosomal L32p protein family 2 57 3.0E-25 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1352 005dc9aa737cfebe6381d687066c2961 58 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 56 20.113 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1352 005dc9aa737cfebe6381d687066c2961 58 SUPERFAMILY SSF57829 1 56 2.38E-20 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CLOST_0636 538a8d5ca9a84e3335abaeb6206e3d58 391 Pfam PF07282 Putative transposase DNA-binding domain 313 382 3.6E-24 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal CLOST_0636 538a8d5ca9a84e3335abaeb6206e3d58 391 Pfam PF12323 Helix-turn-helix domain 2 39 1.8E-11 T 13-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain CLOST_0636 538a8d5ca9a84e3335abaeb6206e3d58 391 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 269 340 7.8E-7 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal CLOST_0636 538a8d5ca9a84e3335abaeb6206e3d58 391 Pfam PF01385 Probable transposase 174 299 6.2E-15 T 13-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CLOST_0467 a839d275353486467277d60b50fc79ff 181 SMART SM00493 3 76 1.0E-6 T 13-10-2018 IPR006171 TOPRIM domain CLOST_0467 a839d275353486467277d60b50fc79ff 181 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 175 30.815 T 13-10-2018 IPR004466 Ribonuclease M5 GO:0043822 CLOST_0467 a839d275353486467277d60b50fc79ff 181 Pfam PF13331 Domain of unknown function (DUF4093) 89 173 1.5E-29 T 13-10-2018 IPR025156 Ribonuclease M5, C-terminal domain CLOST_0467 a839d275353486467277d60b50fc79ff 181 SUPERFAMILY SSF110455 1 114 1.6E-33 T 13-10-2018 CLOST_0467 a839d275353486467277d60b50fc79ff 181 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 174 8.8E-47 T 13-10-2018 IPR004466 Ribonuclease M5 GO:0043822 CLOST_0467 a839d275353486467277d60b50fc79ff 181 Gene3D G3DSA:3.40.1360.20 1 118 3.8E-24 T 13-10-2018 CLOST_0467 a839d275353486467277d60b50fc79ff 181 Pfam PF13662 Toprim domain 3 71 5.2E-7 T 13-10-2018 IPR006171 TOPRIM domain CLOST_0277 0dec62dc60d388867a40e76127375199 311 Gene3D G3DSA:3.20.20.70 1 310 1.3E-84 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0277 0dec62dc60d388867a40e76127375199 311 Pfam PF01180 Dihydroorotate dehydrogenase 2 296 1.2E-60 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CLOST_0277 0dec62dc60d388867a40e76127375199 311 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 1 311 37.139 T 13-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CLOST_0277 0dec62dc60d388867a40e76127375199 311 SUPERFAMILY SSF51395 3 310 1.17E-72 T 13-10-2018 CLOST_0277 0dec62dc60d388867a40e76127375199 311 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 249 269 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CLOST_0277 0dec62dc60d388867a40e76127375199 311 PIRSF PIRSF000164 1 311 5.1E-67 T 13-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CLOST_0277 0dec62dc60d388867a40e76127375199 311 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 3 310 2.9E-95 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 Gene3D G3DSA:3.40.50.10170 308 463 1.6E-42 T 13-10-2018 CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 Gene3D G3DSA:3.30.1180.10 464 591 5.5E-18 T 13-10-2018 CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 SMART SM01120 36 199 1.2E-40 T 13-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 Pfam PF02734 DAK2 domain 36 198 4.0E-31 T 13-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 Pfam PF02645 Uncharacterised protein, DegV family COG1307 312 590 3.7E-59 T 13-10-2018 IPR003797 DegV CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 SMART SM01121 230 590 7.8E-5 T 13-10-2018 IPR033470 Uncharacterised protein, DhaK domain CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 SUPERFAMILY SSF82549 312 590 5.49E-63 T 13-10-2018 CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 Gene3D G3DSA:1.25.40.340 6 198 1.0E-7 T 13-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 312 589 1.6E-68 T 13-10-2018 IPR003797 DegV CLOST_0667 31243280a10b5bee2bab527d6a43b24c 591 SUPERFAMILY SSF101473 3 200 1.57E-35 T 13-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 Gene3D G3DSA:3.40.50.300 382 616 2.3E-94 T 13-10-2018 CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 SUPERFAMILY SSF52540 373 617 2.08E-85 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 Pfam PF00005 ABC transporter 400 549 2.0E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 ProSitePatterns PS00211 ABC transporters family signature. 521 535 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 SMART SM00382 409 602 6.9E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 Gene3D G3DSA:1.20.1560.10 349 381 2.3E-94 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 Pfam PF00664 ABC transporter transmembrane region 22 274 3.6E-47 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 SUPERFAMILY SSF90123 7 336 4.71E-72 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0791 8011cdc2b9aaa70eb689a11af525cf45 623 Gene3D G3DSA:1.20.1560.10 1 340 8.4E-91 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_2441 374b334973765b6574b1a0f742682b8d 203 SUPERFAMILY SSF47413 1 66 6.17E-19 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_2441 374b334973765b6574b1a0f742682b8d 203 SMART SM00530 6 61 4.4E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2441 374b334973765b6574b1a0f742682b8d 203 Gene3D G3DSA:1.10.260.40 1 87 1.6E-22 T 13-10-2018 CLOST_2441 374b334973765b6574b1a0f742682b8d 203 Pfam PF01381 Helix-turn-helix 7 61 2.0E-16 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_0204 06c251e9230810a75f0e64a6fc34b3c5 301 Gene3D G3DSA:3.40.718.10 4 301 1.9E-101 T 13-10-2018 CLOST_0204 06c251e9230810a75f0e64a6fc34b3c5 301 PIRSF PIRSF000428 1 301 3.2E-82 T 13-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_0204 06c251e9230810a75f0e64a6fc34b3c5 301 SUPERFAMILY SSF53659 6 298 3.99E-58 T 13-10-2018 CLOST_0204 06c251e9230810a75f0e64a6fc34b3c5 301 Pfam PF01515 Phosphate acetyl/butaryl transferase 80 296 3.2E-40 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_0204 06c251e9230810a75f0e64a6fc34b3c5 301 Pfam PF01515 Phosphate acetyl/butaryl transferase 7 78 7.5E-5 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_0270 376ed2a5eb28171ff022ce8f0dc764a5 268 Pfam PF00005 ABC transporter 18 166 1.6E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0270 376ed2a5eb28171ff022ce8f0dc764a5 268 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 11 201 4.6E-72 T 13-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 CLOST_0270 376ed2a5eb28171ff022ce8f0dc764a5 268 SMART SM00382 27 215 8.6E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0270 376ed2a5eb28171ff022ce8f0dc764a5 268 Gene3D G3DSA:3.40.50.300 1 243 3.3E-69 T 13-10-2018 CLOST_0270 376ed2a5eb28171ff022ce8f0dc764a5 268 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0270 376ed2a5eb28171ff022ce8f0dc764a5 268 SUPERFAMILY SSF52540 1 226 2.97E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1314 a1513a1fb7f6e554d723b8b8bce8a897 281 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 1 280 1.6E-66 T 13-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CLOST_1314 a1513a1fb7f6e554d723b8b8bce8a897 281 Pfam PF08486 Stage II sporulation protein 1 64 3.3E-15 T 13-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 SMART SM00091 211 277 2.9E-4 T 13-10-2018 IPR000014 PAS domain CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 SUPERFAMILY SSF52540 334 573 5.33E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 SUPERFAMILY SSF55785 200 260 2.66E-6 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 Gene3D G3DSA:1.10.10.10 587 668 9.3E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 Gene3D G3DSA:3.30.450.20 213 311 4.2E-8 T 13-10-2018 CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 Gene3D G3DSA:1.10.8.60 508 581 1.8E-11 T 13-10-2018 CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 359 372 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 Pfam PF13188 PAS domain 213 245 1.4E-5 T 13-10-2018 IPR000014 PAS domain CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 SMART SM00382 355 499 3.5E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 Gene3D G3DSA:3.40.50.300 323 507 1.6E-61 T 13-10-2018 CLOST_0745 bdcd00d2ed54796f1ad13f4ee39464e0 668 Pfam PF00158 Sigma-54 interaction domain 335 502 6.6E-65 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOST_0402 7f27ce9b485ee6e4cffe1cb06cde4ae6 546 SUPERFAMILY SSF55383 454 536 3.27E-20 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0402 7f27ce9b485ee6e4cffe1cb06cde4ae6 546 Pfam PF07833 Copper amine oxidase N-terminal domain 452 543 1.2E-23 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0402 7f27ce9b485ee6e4cffe1cb06cde4ae6 546 Gene3D G3DSA:3.30.457.10 455 532 1.2E-15 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 Gene3D G3DSA:2.160.10.10 225 450 1.2E-64 T 13-10-2018 CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 SUPERFAMILY SSF51161 251 443 1.47E-48 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 SUPERFAMILY SSF53448 3 303 9.46E-62 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 449 1.7E-169 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 448 39.213 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 Pfam PF00483 Nucleotidyl transferase 6 209 6.2E-19 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 392 424 0.0097 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 347 6.2E-7 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 262 296 2.9E-9 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_0472 b6e6f5bcbbcc1b2f73f81900565103c7 451 Gene3D G3DSA:3.90.550.10 1 224 4.4E-63 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 238 250 - T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 235 260 4.6E-61 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 77 97 4.6E-61 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 211 232 4.6E-61 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 97 116 4.6E-61 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 58 77 4.6E-61 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 190 210 4.6E-61 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 128 142 2.6E-14 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 251 261 2.6E-14 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 116 128 2.6E-14 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 183 195 2.6E-14 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 56 65 2.6E-14 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 60 261 6.5E-81 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CLOST_1723 ffbec49c22c6900293f7c7da5f379026 262 Pfam PF00813 FliP family 60 257 4.6E-80 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CLOST_0921 bb11b4b205cb23a034353865530fc015 227 PIRSF PIRSF033094 1 227 4.8E-88 T 13-10-2018 IPR014578 Predicted phosphoesterase, CT488 type CLOST_0921 bb11b4b205cb23a034353865530fc015 227 SUPERFAMILY SSF56300 1 200 2.23E-29 T 13-10-2018 CLOST_0921 bb11b4b205cb23a034353865530fc015 227 Pfam PF00149 Calcineurin-like phosphoesterase 1 194 1.9E-16 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CLOST_0945 6e7731b5688041384698d33b57934ef8 403 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 20 397 8.1E-160 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 CLOST_0945 6e7731b5688041384698d33b57934ef8 403 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 21 402 6.4E-164 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 CLOST_0945 6e7731b5688041384698d33b57934ef8 403 PIRSF PIRSF015658 1 403 1.4E-176 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 CLOST_2317 2e177592a36ace3b336e06a0d5f31693 209 Gene3D G3DSA:3.30.2320.30 85 203 3.8E-11 T 13-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2317 2e177592a36ace3b336e06a0d5f31693 209 SUPERFAMILY SSF160527 85 200 1.06E-11 T 13-10-2018 CLOST_2317 2e177592a36ace3b336e06a0d5f31693 209 Pfam PF01991 ATP synthase (E/31 kDa) subunit 25 194 2.2E-9 T 13-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2338 b766e5fd8bec951285e3c0b9f855330e 308 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 250 284 6.4E-9 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_2338 b766e5fd8bec951285e3c0b9f855330e 308 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 137 170 4.0E-9 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_2338 b766e5fd8bec951285e3c0b9f855330e 308 Gene3D G3DSA:2.160.10.10 101 301 3.8E-55 T 13-10-2018 CLOST_2338 b766e5fd8bec951285e3c0b9f855330e 308 SUPERFAMILY SSF51161 120 303 1.04E-51 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 SUPERFAMILY SSF46589 816 879 1.26E-14 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 Gene3D G3DSA:3.40.50.620 24 526 0.0 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 SUPERFAMILY SSF50677 194 344 9.94E-63 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 Hamap MF_02004 Valine--tRNA ligase [valS]. 4 881 15.79 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 SUPERFAMILY SSF47323 577 831 2.24E-67 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 PRINTS PR00986 Valyl-tRNA synthetase signature 38 49 2.7E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 2.7E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 PRINTS PR00986 Valyl-tRNA synthetase signature 233 250 2.7E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 PRINTS PR00986 Valyl-tRNA synthetase signature 446 467 2.7E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 PRINTS PR00986 Valyl-tRNA synthetase signature 348 361 2.7E-37 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 SUPERFAMILY SSF52374 2 575 2.95E-144 T 13-10-2018 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 564 2.0E-210 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 56 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 Gene3D G3DSA:1.10.730.10 4 744 0.0 T 13-10-2018 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 Gene3D G3DSA:3.90.740.10 178 345 0.0 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 TIGRFAM TIGR00422 valS: valine--tRNA ligase 5 863 0.0 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 816 880 1.6E-18 T 13-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 Gene3D G3DSA:1.10.287.380 809 881 5.9E-16 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CLOST_0622 27fe5af8a24587b0479149ea65f3e0d6 884 Pfam PF08264 Anticodon-binding domain of tRNA 611 756 3.6E-45 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 CLOST_0143 23f659c76aa768fa2b3cbaddb0a7c74f 95 SUPERFAMILY SSF82771 14 82 7.85E-14 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 CLOST_0143 23f659c76aa768fa2b3cbaddb0a7c74f 95 Pfam PF01541 GIY-YIG catalytic domain 15 84 2.3E-16 T 13-10-2018 IPR000305 GIY-YIG endonuclease CLOST_0143 23f659c76aa768fa2b3cbaddb0a7c74f 95 Gene3D G3DSA:3.40.1440.10 8 95 1.7E-32 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 CLOST_0143 23f659c76aa768fa2b3cbaddb0a7c74f 95 SMART SM00465 14 92 8.6E-4 T 13-10-2018 IPR000305 GIY-YIG endonuclease CLOST_1882 a67a0811d9a11c87af63de8b0f0536b1 414 Pfam PF12700 HlyD family secretion protein 254 413 1.1E-9 T 13-10-2018 IPR032681 HlyD family secretion protein CLOST_0317 120a5e663a6cf6f8fb81f2b8bbb6b74e 455 Pfam PF01554 MatE 247 406 3.0E-27 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0317 120a5e663a6cf6f8fb81f2b8bbb6b74e 455 Pfam PF01554 MatE 21 182 1.5E-32 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0317 120a5e663a6cf6f8fb81f2b8bbb6b74e 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 21 419 1.6E-69 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0317 120a5e663a6cf6f8fb81f2b8bbb6b74e 455 PIRSF PIRSF006603 1 451 4.9E-118 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_2296 d30f491c0fac648b5a925e9e5e253e71 175 SUPERFAMILY SSF52833 19 167 4.81E-49 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_2296 d30f491c0fac648b5a925e9e5e253e71 175 Gene3D G3DSA:3.40.30.10 83 175 8.7E-29 T 13-10-2018 CLOST_2296 d30f491c0fac648b5a925e9e5e253e71 175 PIRSF PIRSF000216 6 175 1.1E-53 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2296 d30f491c0fac648b5a925e9e5e253e71 175 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 122 140 - T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_2296 d30f491c0fac648b5a925e9e5e253e71 175 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 22 164 2.6E-51 T 13-10-2018 CLOST_2296 d30f491c0fac648b5a925e9e5e253e71 175 Gene3D G3DSA:1.10.10.1590 16 82 5.1E-17 T 13-10-2018 CLOST_0185 0c52367a520dbba13cbf85063caaf48f 352 SUPERFAMILY SSF52540 6 337 1.5E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0185 0c52367a520dbba13cbf85063caaf48f 352 Pfam PF00437 Type II/IV secretion system protein 12 268 2.1E-42 T 13-10-2018 IPR001482 Type II/IV secretion system protein CLOST_0185 0c52367a520dbba13cbf85063caaf48f 352 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 13-10-2018 IPR001482 Type II/IV secretion system protein CLOST_0185 0c52367a520dbba13cbf85063caaf48f 352 SMART SM00382 122 256 5.7E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0185 0c52367a520dbba13cbf85063caaf48f 352 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 340 3.6E-147 T 13-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 CLOST_0185 0c52367a520dbba13cbf85063caaf48f 352 Gene3D G3DSA:3.40.50.300 102 351 1.2E-97 T 13-10-2018 CLOST_0185 0c52367a520dbba13cbf85063caaf48f 352 Gene3D G3DSA:3.30.450.90 1 100 2.1E-33 T 13-10-2018 CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 Pfam PF02256 Iron hydrogenase small subunit 402 453 3.2E-23 T 13-10-2018 IPR003149 Iron hydrogenase, small subunit CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 SUPERFAMILY SSF53920 39 451 1.19E-131 T 13-10-2018 IPR009016 Iron hydrogenase CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 Gene3D G3DSA:3.30.70.20 1 62 1.4E-13 T 13-10-2018 CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 Gene3D G3DSA:4.10.260.20 395 456 6.8E-21 T 13-10-2018 IPR036991 Iron hydrogenase, small subunit superfamily CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 104 386 1.6E-95 T 13-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 SUPERFAMILY SSF54862 3 71 3.09E-18 T 13-10-2018 CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 81 390 8.0E-129 T 13-10-2018 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 Gene3D G3DSA:3.40.50.1780 86 389 1.5E-130 T 13-10-2018 CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 SMART SM00902 395 454 1.5E-23 T 13-10-2018 IPR003149 Iron hydrogenase, small subunit CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 Pfam PF00037 4Fe-4S binding domain 35 50 1.7E-4 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 Pfam PF00037 4Fe-4S binding domain 4 26 9.7E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0839 8ad52aab9c093ce1ba444703af5cb276 456 Gene3D G3DSA:3.40.950.10 151 380 1.5E-130 T 13-10-2018 CLOST_0146 4039c4d40d05568065e707f67fb0c793 548 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 295 500 5.5E-37 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0146 4039c4d40d05568065e707f67fb0c793 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 1.1E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0146 4039c4d40d05568065e707f67fb0c793 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 329 1.1E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0146 4039c4d40d05568065e707f67fb0c793 548 SMART SM00304 191 243 9.3E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0146 4039c4d40d05568065e707f67fb0c793 548 SMART SM00283 272 547 1.1E-48 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0146 4039c4d40d05568065e707f67fb0c793 548 SUPERFAMILY SSF58104 211 547 2.62E-65 T 13-10-2018 CLOST_0146 4039c4d40d05568065e707f67fb0c793 548 Gene3D G3DSA:1.10.287.950 211 547 2.2E-63 T 13-10-2018 CLOST_0146 4039c4d40d05568065e707f67fb0c793 548 Pfam PF00672 HAMP domain 193 239 3.3E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0847 16aa17b70a65d7db766593073d4f19e6 348 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 231 314 1.6E-5 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CLOST_0847 16aa17b70a65d7db766593073d4f19e6 348 SUPERFAMILY SSF102114 20 300 3.14E-61 T 13-10-2018 CLOST_0847 16aa17b70a65d7db766593073d4f19e6 348 PIRSF PIRSF004762 1 324 3.0E-72 T 13-10-2018 CLOST_0847 16aa17b70a65d7db766593073d4f19e6 348 SMART SM00876 227 331 0.0014 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CLOST_0847 16aa17b70a65d7db766593073d4f19e6 348 Gene3D G3DSA:3.20.20.70 1 346 2.1E-118 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0847 16aa17b70a65d7db766593073d4f19e6 348 TIGRFAM TIGR03956 rSAM_HydE: [FeFe] hydrogenase H-cluster radical SAM maturase HydE 4 342 5.4E-144 T 13-10-2018 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM CLOST_0847 16aa17b70a65d7db766593073d4f19e6 348 Pfam PF04055 Radical SAM superfamily 56 217 2.1E-19 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0847 16aa17b70a65d7db766593073d4f19e6 348 SMART SM00729 52 262 4.6E-30 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0040 f0c20cc99a8ac8ec2aef9798b4e20449 313 SUPERFAMILY SSF53850 38 311 4.1E-69 T 13-10-2018 CLOST_0040 f0c20cc99a8ac8ec2aef9798b4e20449 313 Gene3D G3DSA:3.40.190.10 40 309 3.8E-103 T 13-10-2018 CLOST_0040 f0c20cc99a8ac8ec2aef9798b4e20449 313 Gene3D G3DSA:3.40.190.120 140 249 3.8E-103 T 13-10-2018 CLOST_0040 f0c20cc99a8ac8ec2aef9798b4e20449 313 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 38 307 4.1E-65 T 13-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 CLOST_2361 54b74cd47796ddabba080c0b25c7d326 266 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 188 264 7.6E-26 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CLOST_2361 54b74cd47796ddabba080c0b25c7d326 266 SUPERFAMILY SSF117143 89 226 4.84E-29 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like CLOST_2361 54b74cd47796ddabba080c0b25c7d326 266 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 152 247 1.3E-28 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G CLOST_2361 54b74cd47796ddabba080c0b25c7d326 266 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 138 5.8E-46 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G CLOST_2361 54b74cd47796ddabba080c0b25c7d326 266 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 245 6.6E-54 T 13-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 CLOST_2361 54b74cd47796ddabba080c0b25c7d326 266 Pfam PF00460 Flagella basal body rod protein 4 34 4.4E-14 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CLOST_2361 54b74cd47796ddabba080c0b25c7d326 266 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 3 264 9.9E-84 T 13-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 113 126 1.2E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 1.2E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 1.2E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 1.2E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 1.2E-42 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 317 1.5E-69 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 154 161 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 SUPERFAMILY SSF55347 156 318 1.15E-72 T 13-10-2018 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 SUPERFAMILY SSF51735 2 172 1.77E-61 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0642 8509787b8079d93cd465786db8f81afc 339 PIRSF PIRSF000149 1 338 5.7E-134 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 Gene3D G3DSA:3.40.50.720 3 333 5.5E-151 T 13-10-2018 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 SMART SM00846 2 156 6.4E-85 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 329 4.1E-136 T 13-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2 106 8.7E-34 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0642 8509787b8079d93cd465786db8f81afc 339 Gene3D G3DSA:3.30.360.10 155 319 5.5E-151 T 13-10-2018 CLOST_1459 f068e75ae70e1d28b7a97abf5a8e3f97 275 SUPERFAMILY SSF52821 4 133 3.67E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1459 f068e75ae70e1d28b7a97abf5a8e3f97 275 SUPERFAMILY SSF52821 157 270 5.63E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1459 f068e75ae70e1d28b7a97abf5a8e3f97 275 Gene3D G3DSA:3.40.250.10 157 275 4.0E-23 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1459 f068e75ae70e1d28b7a97abf5a8e3f97 275 Gene3D G3DSA:3.40.250.10 1 141 2.1E-38 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1459 f068e75ae70e1d28b7a97abf5a8e3f97 275 Pfam PF00581 Rhodanese-like domain 156 263 4.3E-7 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1459 f068e75ae70e1d28b7a97abf5a8e3f97 275 Pfam PF00581 Rhodanese-like domain 7 121 4.3E-16 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1459 f068e75ae70e1d28b7a97abf5a8e3f97 275 SMART SM00450 3 128 2.2E-12 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1459 f068e75ae70e1d28b7a97abf5a8e3f97 275 SMART SM00450 154 270 2.5E-10 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1729 5ed2dd3dcd217d489e41eee6ca553ffb 216 Gene3D G3DSA:3.30.1330.60 43 214 5.8E-51 T 13-10-2018 IPR036737 OmpA-like domain superfamily CLOST_1729 5ed2dd3dcd217d489e41eee6ca553ffb 216 SUPERFAMILY SSF103088 85 203 1.44E-31 T 13-10-2018 IPR036737 OmpA-like domain superfamily CLOST_1729 5ed2dd3dcd217d489e41eee6ca553ffb 216 Pfam PF00691 OmpA family 95 197 1.8E-20 T 13-10-2018 IPR006665 OmpA-like domain CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 Gene3D G3DSA:3.50.50.60 121 249 1.9E-110 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 4.7E-35 T 13-10-2018 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 4.7E-35 T 13-10-2018 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 4.7E-35 T 13-10-2018 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.7E-35 T 13-10-2018 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 4.7E-35 T 13-10-2018 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 SUPERFAMILY SSF51905 1 308 2.29E-51 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 Gene3D G3DSA:3.50.50.60 8 308 1.9E-110 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 5 309 2.9E-112 T 13-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 298 2.7E-54 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1108 38f06997d3b410e71f8e8de967e7ca13 314 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 4.7E-72 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1074 688de038a7779ee7bf847c86e6e5d6f3 703 SUPERFAMILY SSF55874 529 679 1.78E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_1074 688de038a7779ee7bf847c86e6e5d6f3 703 SMART SM00388 474 540 7.6E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1074 688de038a7779ee7bf847c86e6e5d6f3 703 SMART SM00387 588 697 4.0E-5 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1074 688de038a7779ee7bf847c86e6e5d6f3 703 Pfam PF00512 His Kinase A (phospho-acceptor) domain 475 539 6.1E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_1074 688de038a7779ee7bf847c86e6e5d6f3 703 Gene3D G3DSA:1.10.287.130 465 541 3.0E-20 T 13-10-2018 CLOST_1074 688de038a7779ee7bf847c86e6e5d6f3 703 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 589 680 9.8E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1074 688de038a7779ee7bf847c86e6e5d6f3 703 SUPERFAMILY SSF47384 461 541 9.22E-18 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_1074 688de038a7779ee7bf847c86e6e5d6f3 703 Gene3D G3DSA:3.30.565.10 542 696 5.1E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 SUPERFAMILY SSF103491 1 414 3.79E-125 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 418 3.0E-127 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 ProSitePatterns PS00755 Protein secY signature 1. 70 89 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 423 30.396 T 13-10-2018 IPR026593 Protein translocase subunit SecY CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 ProSitePatterns PS00756 Protein secY signature 2. 162 179 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PIRSF PIRSF004557 1 424 1.3E-121 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 143 168 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 169 192 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 69 89 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 360 378 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 261 280 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 305 327 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 PRINTS PR00303 Preprotein translocase SecY subunit signature 392 410 7.0E-98 T 13-10-2018 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 Pfam PF00344 SecY translocase 70 407 1.2E-118 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_2178 08528f3fda9ed29109297f80c9bbcd30 424 Gene3D G3DSA:1.10.3370.10 1 419 5.0E-167 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_2078 83ae2241c612b7da6719c3e77d8e7db3 441 PIRSF PIRSF006603 2 441 1.2E-99 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_2078 83ae2241c612b7da6719c3e77d8e7db3 441 TIGRFAM TIGR00797 matE: MATE efflux family protein 14 413 3.5E-73 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_2078 83ae2241c612b7da6719c3e77d8e7db3 441 Pfam PF01554 MatE 14 175 5.3E-28 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_2078 83ae2241c612b7da6719c3e77d8e7db3 441 Pfam PF01554 MatE 240 400 4.8E-23 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 387 431 4.4E-16 T 13-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 SUPERFAMILY SSF56037 364 458 6.93E-21 T 13-10-2018 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 SMART SM00977 387 459 6.4E-23 T 13-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 Pfam PF11734 TilS substrate C-terminal domain 388 459 8.1E-14 T 13-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 Pfam PF01171 PP-loop family 21 201 3.3E-52 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 SUPERFAMILY SSF52402 8 235 1.08E-58 T 13-10-2018 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 Gene3D G3DSA:3.50.40.10 347 460 4.2E-7 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 Gene3D G3DSA:3.40.50.620 1 212 1.7E-71 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 Gene3D G3DSA:1.20.59.30 245 329 2.0E-13 T 13-10-2018 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 SUPERFAMILY SSF82829 215 321 8.37E-18 T 13-10-2018 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 206 2.5E-59 T 13-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOST_0936 a4af019961bb2ce319127a78397c04fb 464 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 6 317 24.67 T 13-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CLOST_0416 e10798c4a4f7e19c7d0eea395a624467 169 SUPERFAMILY SSF52016 4 158 5.3E-46 T 13-10-2018 CLOST_0416 e10798c4a4f7e19c7d0eea395a624467 169 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 163 36.892 T 13-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 CLOST_0416 e10798c4a4f7e19c7d0eea395a624467 169 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 159 2.5E-60 T 13-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 CLOST_0416 e10798c4a4f7e19c7d0eea395a624467 169 Gene3D G3DSA:3.20.19.10 2 168 6.3E-55 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 CLOST_0416 e10798c4a4f7e19c7d0eea395a624467 169 Pfam PF00694 Aconitase C-terminal domain 50 101 9.3E-20 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 CLOST_0416 e10798c4a4f7e19c7d0eea395a624467 169 TIGRFAM TIGR02084 leud: 3-isopropylmalate dehydratase, small subunit 5 157 2.1E-77 T 13-10-2018 IPR011824 Hydrolyase LeuD/DmdB, bacterial GO:0016836 KEGG: 00290+4.2.1.33 CLOST_1725 f962849da37da9cd6e54bc21d8221e7b 120 Gene3D G3DSA:3.40.50.2300 3 120 9.9E-40 T 13-10-2018 CLOST_1725 f962849da37da9cd6e54bc21d8221e7b 120 SMART SM00448 3 115 2.5E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1725 f962849da37da9cd6e54bc21d8221e7b 120 SUPERFAMILY SSF52172 4 119 4.7E-41 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1725 f962849da37da9cd6e54bc21d8221e7b 120 Pfam PF00072 Response regulator receiver domain 5 116 7.7E-34 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1984 1e25854eca3dd0dad97187c3b945ecc3 372 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 51 2.7E-10 T 13-10-2018 CLOST_1984 1e25854eca3dd0dad97187c3b945ecc3 372 SUPERFAMILY SSF46785 3 56 1.05E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1984 1e25854eca3dd0dad97187c3b945ecc3 372 Gene3D G3DSA:1.10.10.10 1 54 6.6E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1984 1e25854eca3dd0dad97187c3b945ecc3 372 Pfam PF00294 pfkB family carbohydrate kinase 62 351 2.7E-52 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB CLOST_1984 1e25854eca3dd0dad97187c3b945ecc3 372 Gene3D G3DSA:3.40.1190.20 57 371 8.8E-76 T 13-10-2018 IPR029056 Ribokinase-like CLOST_1984 1e25854eca3dd0dad97187c3b945ecc3 372 SUPERFAMILY SSF53613 64 363 1.56E-56 T 13-10-2018 IPR029056 Ribokinase-like CLOST_0153 21a72f2f3541cada4a4c6037eead5f19 372 Gene3D G3DSA:2.30.30.280 209 276 5.0E-23 T 13-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 CLOST_0153 21a72f2f3541cada4a4c6037eead5f19 372 SUPERFAMILY SSF52402 1 241 1.01E-53 T 13-10-2018 CLOST_0153 21a72f2f3541cada4a4c6037eead5f19 372 Gene3D G3DSA:2.40.30.10 277 362 2.1E-24 T 13-10-2018 CLOST_0153 21a72f2f3541cada4a4c6037eead5f19 372 Pfam PF03054 tRNA methyl transferase 3 355 1.0E-139 T 13-10-2018 CLOST_0153 21a72f2f3541cada4a4c6037eead5f19 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 3 356 39.622 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 CLOST_0153 21a72f2f3541cada4a4c6037eead5f19 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 3 355 8.3E-136 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 CLOST_0153 21a72f2f3541cada4a4c6037eead5f19 372 Gene3D G3DSA:3.40.50.620 1 208 7.8E-96 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 PIRSF PIRSF001423 80 660 5.1E-179 T 13-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 Pfam PF01175 Urocanase Rossmann-like domain 217 440 1.8E-82 T 13-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 Pfam PF17391 Urocanase N-terminal domain 89 214 5.6E-51 T 13-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 TIGRFAM TIGR01228 hutU: urocanate hydratase 102 642 6.3E-132 T 13-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 Pfam PF17392 Urocanase C-terminal domain 445 641 5.8E-82 T 13-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 ProSitePatterns PS01233 Urocanase signature. 538 553 - T 13-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 SUPERFAMILY SSF111326 80 648 7.85E-224 T 13-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 Gene3D G3DSA:3.40.1770.10 446 649 8.2E-88 T 13-10-2018 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 Gene3D G3DSA:3.40.1770.10 79 222 1.2E-45 T 13-10-2018 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 Gene3D G3DSA:3.40.50.10730 223 439 2.3E-79 T 13-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0027 43c79b56e1dd050bafff7e171344dc52 676 Hamap MF_00577 Urocanate hydratase [hutU]. 59 658 42.982 T 13-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_0545 9cd273c3d545d7ba4a4db0d083631adb 90 PIRSF PIRSF002599 5 88 1.0E-10 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 CLOST_0545 9cd273c3d545d7ba4a4db0d083631adb 90 Pfam PF06961 Protein of unknown function (DUF1294) 15 69 5.1E-25 T 13-10-2018 IPR010718 Protein of unknown function DUF1294 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 Gene3D G3DSA:3.40.50.880 1 190 1.8E-62 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00097 Anthranilate synthase component II signature 119 131 5.4E-33 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.4E-33 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00097 Anthranilate synthase component II signature 99 107 5.4E-33 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00097 Anthranilate synthase component II signature 74 85 5.4E-33 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00097 Anthranilate synthase component II signature 47 56 5.4E-33 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00097 Anthranilate synthase component II signature 164 177 5.4E-33 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 Pfam PF00117 Glutamine amidotransferase class-I 4 185 5.1E-55 T 13-10-2018 IPR017926 Glutamine amidotransferase CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 6.7E-14 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 6.7E-14 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 6.7E-14 T 13-10-2018 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 2 186 3.6E-69 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CLOST_1764 81dd5fdb8844075003656bcfbeadbb15 192 SUPERFAMILY SSF52317 2 191 3.63E-57 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_2055 fa94af5ba66b8dd1b307845e6ccff89d 431 SUPERFAMILY SSF55486 276 391 8.55E-5 T 13-10-2018 CLOST_0113 9227c7a85639bc64cd3c2b2d723111c1 199 SUPERFAMILY SSF55469 4 198 8.25E-74 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_0113 9227c7a85639bc64cd3c2b2d723111c1 199 Pfam PF00881 Nitroreductase family 9 178 6.1E-20 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CLOST_0113 9227c7a85639bc64cd3c2b2d723111c1 199 Gene3D G3DSA:3.40.109.10 2 199 1.3E-90 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_0711 f82b28842e7c1a8aacbd02e3e89bf5c3 182 SUPERFAMILY SSF47240 46 171 6.09E-13 T 13-10-2018 IPR009078 Ferritin-like superfamily CLOST_0711 f82b28842e7c1a8aacbd02e3e89bf5c3 182 Pfam PF09968 Uncharacterized protein domain (DUF2202) 49 173 2.5E-10 T 13-10-2018 IPR019243 Domain of unknown function DUF2202 CLOST_0711 f82b28842e7c1a8aacbd02e3e89bf5c3 182 Gene3D G3DSA:1.20.1260.10 45 181 1.7E-19 T 13-10-2018 IPR012347 Ferritin-like CLOST_2008 c99a91561e756544808a46c0115bb931 217 Gene3D G3DSA:3.20.20.70 4 212 4.4E-73 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_2008 c99a91561e756544808a46c0115bb931 217 SUPERFAMILY SSF51391 8 212 3.01E-65 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2008 c99a91561e756544808a46c0115bb931 217 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 13 207 7.2E-67 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2008 c99a91561e756544808a46c0115bb931 217 Pfam PF02581 Thiamine monophosphate synthase 14 194 8.9E-64 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2008 c99a91561e756544808a46c0115bb931 217 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 212 27.374 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2011 ab8502557c4ec6b0c15a68242469b086 166 TIGRFAM TIGR02359 thiW: energy coupling factor transporter S component ThiW 3 150 2.6E-48 T 13-10-2018 IPR012652 Energy coupling factor transporter S component ThiW CLOST_2011 ab8502557c4ec6b0c15a68242469b086 166 PIRSF PIRSF024534 1 160 2.3E-54 T 13-10-2018 IPR012652 Energy coupling factor transporter S component ThiW CLOST_2011 ab8502557c4ec6b0c15a68242469b086 166 Pfam PF09512 Thiamine-precursor transporter protein (ThiW) 6 150 2.8E-53 T 13-10-2018 IPR012652 Energy coupling factor transporter S component ThiW CLOST_2011 ab8502557c4ec6b0c15a68242469b086 166 Gene3D G3DSA:1.10.1760.20 2 160 2.5E-10 T 13-10-2018 CLOST_1199 93a11ffb26f2c64645e72079132dcd69 158 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 25 150 2.2E-30 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 CLOST_2379 dfe705b7c9c1b9f2d2a3e25904b20cde 352 SUPERFAMILY SSF56796 6 341 5.76E-99 T 13-10-2018 CLOST_2379 dfe705b7c9c1b9f2d2a3e25904b20cde 352 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 351 62.801 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CLOST_2379 dfe705b7c9c1b9f2d2a3e25904b20cde 352 Gene3D G3DSA:1.20.1090.10 175 352 1.1E-53 T 13-10-2018 CLOST_2379 dfe705b7c9c1b9f2d2a3e25904b20cde 352 Pfam PF01761 3-dehydroquinate synthase 69 323 4.6E-97 T 13-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CLOST_2379 dfe705b7c9c1b9f2d2a3e25904b20cde 352 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 343 2.0E-111 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CLOST_2379 dfe705b7c9c1b9f2d2a3e25904b20cde 352 PIRSF PIRSF001455 4 349 4.1E-104 T 13-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CLOST_2379 dfe705b7c9c1b9f2d2a3e25904b20cde 352 Gene3D G3DSA:3.40.50.1970 1 174 2.7E-65 T 13-10-2018 CLOST_0754 a6e63e5f967bfb1d346b6069456a50fe 86 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0754 a6e63e5f967bfb1d346b6069456a50fe 86 Gene3D G3DSA:3.30.70.20 6 53 9.7E-7 T 13-10-2018 CLOST_0754 a6e63e5f967bfb1d346b6069456a50fe 86 Gene3D G3DSA:3.30.70.20 54 86 1.9E-7 T 13-10-2018 CLOST_0754 a6e63e5f967bfb1d346b6069456a50fe 86 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 34 45 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0754 a6e63e5f967bfb1d346b6069456a50fe 86 Pfam PF14697 4Fe-4S dicluster domain 29 81 5.1E-9 T 13-10-2018 CLOST_0754 a6e63e5f967bfb1d346b6069456a50fe 86 SUPERFAMILY SSF54862 14 84 2.59E-21 T 13-10-2018 CLOST_0754 a6e63e5f967bfb1d346b6069456a50fe 86 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 16 84 1.5E-29 T 13-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 SUPERFAMILY SSF53271 236 443 1.7E-66 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 440 46.058 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 SUPERFAMILY SSF56235 2 224 1.37E-70 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 Gene3D G3DSA:3.60.20.10 2 441 1.5E-158 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 Pfam PF13537 Glutamine amidotransferase domain 82 196 2.2E-21 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 Gene3D G3DSA:3.40.50.2020 260 424 1.5E-158 T 13-10-2018 CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 441 2.5E-160 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 Pfam PF00156 Phosphoribosyl transferase domain 274 370 3.6E-7 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOST_0335 dee3e4c4469b95066ff10bf0cef9be1e 447 PIRSF PIRSF000485 1 445 3.6E-172 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CLOST_1050 f292a0b5b0107ee7be2a46841005a4a3 430 Gene3D G3DSA:1.20.1250.20 213 417 6.2E-9 T 13-10-2018 CLOST_1050 f292a0b5b0107ee7be2a46841005a4a3 430 Pfam PF05977 Transmembrane secretion effector 4 415 1.6E-22 T 13-10-2018 IPR010290 Transmembrane secretion effector CLOST_1050 f292a0b5b0107ee7be2a46841005a4a3 430 SUPERFAMILY SSF103473 7 405 1.05E-37 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_1050 f292a0b5b0107ee7be2a46841005a4a3 430 Gene3D G3DSA:1.20.1250.20 1 195 5.8E-16 T 13-10-2018 CLOST_1140 177a4bb5f2a9319feecdc8b731e27e3a 216 Pfam PF02080 TrkA-C domain 150 214 5.1E-18 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CLOST_1140 177a4bb5f2a9319feecdc8b731e27e3a 216 Gene3D G3DSA:3.40.50.720 1 136 2.1E-40 T 13-10-2018 CLOST_1140 177a4bb5f2a9319feecdc8b731e27e3a 216 Pfam PF02254 TrkA-N domain 4 119 4.9E-31 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CLOST_1140 177a4bb5f2a9319feecdc8b731e27e3a 216 SUPERFAMILY SSF51735 2 133 1.63E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1140 177a4bb5f2a9319feecdc8b731e27e3a 216 SUPERFAMILY SSF116726 130 214 1.7E-21 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CLOST_1140 177a4bb5f2a9319feecdc8b731e27e3a 216 Gene3D G3DSA:3.30.70.1450 137 216 4.6E-29 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CLOST_2440 d7ce74cac9a08926ff4cd0ced06b5feb 242 SMART SM00382 26 216 2.0E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2440 d7ce74cac9a08926ff4cd0ced06b5feb 242 Pfam PF00005 ABC transporter 18 168 2.0E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2440 d7ce74cac9a08926ff4cd0ced06b5feb 242 PIRSF PIRSF039085 1 242 8.2E-93 T 13-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CLOST_2440 d7ce74cac9a08926ff4cd0ced06b5feb 242 SUPERFAMILY SSF52540 1 238 3.13E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2440 d7ce74cac9a08926ff4cd0ced06b5feb 242 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2440 d7ce74cac9a08926ff4cd0ced06b5feb 242 Gene3D G3DSA:3.40.50.300 1 241 1.2E-76 T 13-10-2018 CLOST_0527 12a2219bb8f3f6fa4552af0f32234091 110 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 105 6.0E-16 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CLOST_0527 12a2219bb8f3f6fa4552af0f32234091 110 Gene3D G3DSA:3.10.20.400 5 97 4.4E-37 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 CLOST_0527 12a2219bb8f3f6fa4552af0f32234091 110 SUPERFAMILY SSF141734 9 109 9.42E-45 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 CLOST_0527 12a2219bb8f3f6fa4552af0f32234091 110 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 106 1.7E-32 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CLOST_0493 b9f6766c057bf17f771d34a771a0e9f8 184 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 177 2.7E-34 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CLOST_0493 b9f6766c057bf17f771d34a771a0e9f8 184 Gene3D G3DSA:3.40.920.10 2 184 8.4E-55 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_0493 b9f6766c057bf17f771d34a771a0e9f8 184 SUPERFAMILY SSF53323 3 181 3.92E-44 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_0493 b9f6766c057bf17f771d34a771a0e9f8 184 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 6 180 2.1E-25 T 13-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 CLOST_0954 383e601d3749aca7d577b1fd6cdf8ab7 385 SUPERFAMILY SSF53383 2 381 3.4E-103 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0954 383e601d3749aca7d577b1fd6cdf8ab7 385 Gene3D G3DSA:3.40.640.10 61 282 6.2E-120 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0954 383e601d3749aca7d577b1fd6cdf8ab7 385 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CLOST_0954 383e601d3749aca7d577b1fd6cdf8ab7 385 Pfam PF00155 Aminotransferase class I and II 30 376 1.5E-64 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_0954 383e601d3749aca7d577b1fd6cdf8ab7 385 Gene3D G3DSA:3.90.1150.10 24 376 6.2E-120 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_2168 65abbca7d134a6c4954335421e06b6f7 305 SMART SM01324 214 300 2.1E-7 T 13-10-2018 IPR025582 YARHG domain CLOST_2168 65abbca7d134a6c4954335421e06b6f7 305 Gene3D G3DSA:1.20.58.1690 212 298 9.4E-17 T 13-10-2018 IPR038434 YARHG domain superfamily CLOST_2168 65abbca7d134a6c4954335421e06b6f7 305 Pfam PF13308 YARHG domain 216 299 9.0E-16 T 13-10-2018 IPR025582 YARHG domain CLOST_2069 c03e398e055ca71b20b6adc9e3fe3898 207 Pfam PF08348 YheO-like PAS domain 7 116 2.2E-29 T 13-10-2018 IPR013559 YheO-like CLOST_2069 c03e398e055ca71b20b6adc9e3fe3898 207 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 15 118 3.0E-9 T 13-10-2018 IPR013559 YheO-like CLOST_2069 c03e398e055ca71b20b6adc9e3fe3898 207 Pfam PF13309 HTH domain 142 203 4.2E-20 T 13-10-2018 IPR039445 Transcriptional regulator DauR-like, HTH domain CLOST_0219 861b88c1285379644cfa602f6b10410c 790 SMART SM00488 181 411 2.8E-4 T 13-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 CLOST_0219 861b88c1285379644cfa602f6b10410c 790 Pfam PF13307 Helicase C-terminal domain 602 766 3.2E-40 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CLOST_0219 861b88c1285379644cfa602f6b10410c 790 SUPERFAMILY SSF52540 203 750 1.64E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0219 861b88c1285379644cfa602f6b10410c 790 Gene3D G3DSA:3.40.50.300 198 555 2.0E-51 T 13-10-2018 CLOST_0219 861b88c1285379644cfa602f6b10410c 790 Pfam PF06733 DEAD_2 288 394 4.8E-10 T 13-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CLOST_0219 861b88c1285379644cfa602f6b10410c 790 Gene3D G3DSA:3.90.320.10 17 160 3.2E-7 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal CLOST_0219 861b88c1285379644cfa602f6b10410c 790 Gene3D G3DSA:3.40.50.300 571 781 3.1E-53 T 13-10-2018 CLOST_0219 861b88c1285379644cfa602f6b10410c 790 Gene3D G3DSA:1.10.30.20 275 332 2.0E-51 T 13-10-2018 CLOST_0219 861b88c1285379644cfa602f6b10410c 790 Gene3D G3DSA:1.10.275.40 389 522 2.0E-51 T 13-10-2018 CLOST_0219 861b88c1285379644cfa602f6b10410c 790 Pfam PF12705 PD-(D/E)XK nuclease superfamily 38 156 2.4E-5 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type CLOST_0219 861b88c1285379644cfa602f6b10410c 790 SMART SM00491 618 755 8.6E-15 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CLOST_0638 ea996a39e426eb1f44afeb1754dca9be 293 SUPERFAMILY SSF64397 3 242 1.83E-71 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CLOST_0638 ea996a39e426eb1f44afeb1754dca9be 293 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 291 37.298 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CLOST_0638 ea996a39e426eb1f44afeb1754dca9be 293 PIRSF PIRSF005261 1 291 1.8E-81 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CLOST_0638 ea996a39e426eb1f44afeb1754dca9be 293 Pfam PF01430 Hsp33 protein 3 280 8.8E-89 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CLOST_0638 ea996a39e426eb1f44afeb1754dca9be 293 Gene3D G3DSA:3.55.30.10 1 233 1.0E-85 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CLOST_0638 ea996a39e426eb1f44afeb1754dca9be 293 Gene3D G3DSA:3.90.1280.10 234 291 7.2E-22 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CLOST_0638 ea996a39e426eb1f44afeb1754dca9be 293 SUPERFAMILY SSF118352 232 289 5.36E-20 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CLOST_1405 358646c226320c7f97b4494e00fa890b 178 Pfam PF01464 Transglycosylase SLT domain 37 143 4.0E-27 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 CLOST_1405 358646c226320c7f97b4494e00fa890b 178 Gene3D G3DSA:1.10.530.10 28 178 4.9E-38 T 13-10-2018 CLOST_1405 358646c226320c7f97b4494e00fa890b 178 SUPERFAMILY SSF53955 9 173 5.63E-35 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily CLOST_1816 d8228f9fe32f04f905524ee76fc341cb 113 Gene3D G3DSA:3.30.1360.20 22 113 2.2E-31 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 CLOST_1816 d8228f9fe32f04f905524ee76fc341cb 113 SUPERFAMILY SSF55248 22 112 2.88E-29 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 CLOST_1816 d8228f9fe32f04f905524ee76fc341cb 113 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 23 110 4.5E-28 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 CLOST_1816 d8228f9fe32f04f905524ee76fc341cb 113 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 19 112 21.906 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 PIRSF PIRSF002133 1 137 5.9E-49 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 Gene3D G3DSA:2.40.50.140 1 140 3.6E-60 T 13-10-2018 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 SUPERFAMILY SSF50249 3 136 9.71E-48 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2209 2f186f986169ef934f3938a6658bc847 140 Pfam PF00164 Ribosomal protein S12/S23 39 136 1.8E-39 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.266 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 2.2E-66 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2209 2f186f986169ef934f3938a6658bc847 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.2E-57 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2143 7f3a5bdd4558ead8a53b543be700accc 278 SUPERFAMILY SSF53790 6 222 1.31E-80 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 CLOST_2143 7f3a5bdd4558ead8a53b543be700accc 278 Gene3D G3DSA:3.30.950.10 114 230 4.7E-38 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 CLOST_2143 7f3a5bdd4558ead8a53b543be700accc 278 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 6 224 36.52 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 CLOST_2143 7f3a5bdd4558ead8a53b543be700accc 278 PIRSF PIRSF005917 1 278 3.5E-102 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 CLOST_2143 7f3a5bdd4558ead8a53b543be700accc 278 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 205 4.4E-28 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 CLOST_2143 7f3a5bdd4558ead8a53b543be700accc 278 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 84 95 - T 13-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 CLOST_2143 7f3a5bdd4558ead8a53b543be700accc 278 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 7 275 4.0E-87 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 CLOST_2143 7f3a5bdd4558ead8a53b543be700accc 278 Gene3D G3DSA:3.40.1010.10 1 113 3.1E-45 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 CLOST_0230 02804119b52dfd36efac200a3cacd3dd 367 SUPERFAMILY SSF51604 116 357 1.24E-62 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily CLOST_0230 02804119b52dfd36efac200a3cacd3dd 367 SMART SM00922 145 243 1.3E-29 T 13-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CLOST_0230 02804119b52dfd36efac200a3cacd3dd 367 SUPERFAMILY SSF54826 5 129 6.39E-35 T 13-10-2018 CLOST_0230 02804119b52dfd36efac200a3cacd3dd 367 Gene3D G3DSA:3.30.390.10 10 119 3.2E-117 T 13-10-2018 IPR029017 Enolase-like, N-terminal CLOST_0230 02804119b52dfd36efac200a3cacd3dd 367 Gene3D G3DSA:3.20.20.120 120 355 3.2E-117 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily CLOST_0230 02804119b52dfd36efac200a3cacd3dd 367 Pfam PF13378 Enolase C-terminal domain-like 147 357 5.7E-46 T 13-10-2018 IPR029065 Enolase C-terminal domain-like CLOST_0230 02804119b52dfd36efac200a3cacd3dd 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 128 2.8E-22 T 13-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CLOST_1715 b0592dd20f87c3294421c747727a126f 357 SMART SM00448 4 118 9.0E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1715 b0592dd20f87c3294421c747727a126f 357 Gene3D G3DSA:3.40.50.180 159 356 1.3E-68 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal CLOST_1715 b0592dd20f87c3294421c747727a126f 357 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 356 37.783 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CLOST_1715 b0592dd20f87c3294421c747727a126f 357 Gene3D G3DSA:3.40.50.2300 1 133 8.9E-32 T 13-10-2018 CLOST_1715 b0592dd20f87c3294421c747727a126f 357 SUPERFAMILY SSF52738 165 355 7.32E-61 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal CLOST_1715 b0592dd20f87c3294421c747727a126f 357 PIRSF PIRSF000876 1 357 3.3E-127 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CLOST_1715 b0592dd20f87c3294421c747727a126f 357 SUPERFAMILY SSF52172 1 112 3.56E-29 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1715 b0592dd20f87c3294421c747727a126f 357 Pfam PF01339 CheB methylesterase 170 351 2.8E-59 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CLOST_1715 b0592dd20f87c3294421c747727a126f 357 Pfam PF00072 Response regulator receiver domain 6 114 3.8E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0776 5feb4c2a38ae5826146961f67b5445a4 378 Pfam PF02754 Cysteine-rich domain 126 205 1.4E-6 T 13-10-2018 IPR004017 Cysteine-rich domain CLOST_0776 5feb4c2a38ae5826146961f67b5445a4 378 Pfam PF02754 Cysteine-rich domain 253 332 2.6E-7 T 13-10-2018 IPR004017 Cysteine-rich domain CLOST_0776 5feb4c2a38ae5826146961f67b5445a4 378 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 58 69 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0776 5feb4c2a38ae5826146961f67b5445a4 378 Pfam PF13183 4Fe-4S dicluster domain 16 72 1.6E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0776 5feb4c2a38ae5826146961f67b5445a4 378 Gene3D G3DSA:3.30.70.3270 5 116 1.1E-8 T 13-10-2018 CLOST_0776 5feb4c2a38ae5826146961f67b5445a4 378 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 17 28 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0776 5feb4c2a38ae5826146961f67b5445a4 378 SUPERFAMILY SSF46548 3 86 2.62E-15 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_1801 80c39e63132941ffa48b5c51c3b0017c 305 Gene3D G3DSA:3.40.50.10800 87 300 2.5E-105 T 13-10-2018 CLOST_1801 80c39e63132941ffa48b5c51c3b0017c 305 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 4 301 1.3E-95 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CLOST_1801 80c39e63132941ffa48b5c51c3b0017c 305 SUPERFAMILY SSF142754 4 301 1.15E-102 T 13-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CLOST_1801 80c39e63132941ffa48b5c51c3b0017c 305 Gene3D G3DSA:3.40.50.10800 9 283 2.5E-105 T 13-10-2018 CLOST_1801 80c39e63132941ffa48b5c51c3b0017c 305 Pfam PF02445 Quinolinate synthetase A protein 9 300 4.3E-110 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CLOST_1801 80c39e63132941ffa48b5c51c3b0017c 305 Gene3D G3DSA:3.40.50.10800 171 257 2.5E-105 T 13-10-2018 CLOST_2270 4f8615a8d25e6138a3c01beee062d093 528 PIRSF PIRSF002741 1 525 9.9E-79 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CLOST_2270 4f8615a8d25e6138a3c01beee062d093 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 438 3.6E-64 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain CLOST_2270 4f8615a8d25e6138a3c01beee062d093 528 Gene3D G3DSA:3.10.105.10 283 494 1.2E-96 T 13-10-2018 CLOST_2270 4f8615a8d25e6138a3c01beee062d093 528 SUPERFAMILY SSF53850 53 518 5.43E-96 T 13-10-2018 CLOST_2270 4f8615a8d25e6138a3c01beee062d093 528 Gene3D G3DSA:3.90.76.10 76 193 1.2E-96 T 13-10-2018 CLOST_2270 4f8615a8d25e6138a3c01beee062d093 528 Gene3D G3DSA:3.40.190.10 67 499 1.2E-96 T 13-10-2018 CLOST_0387 4ad6922115643bca5f9d5d85a7949f25 406 Gene3D G3DSA:3.90.1200.10 118 405 2.5E-91 T 13-10-2018 CLOST_0387 4ad6922115643bca5f9d5d85a7949f25 406 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 406 154.575 T 13-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 CLOST_0387 4ad6922115643bca5f9d5d85a7949f25 406 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 36 404 4.3E-94 T 13-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 CLOST_0387 4ad6922115643bca5f9d5d85a7949f25 406 Pfam PF01636 Phosphotransferase enzyme family 223 266 2.8E-9 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase CLOST_0387 4ad6922115643bca5f9d5d85a7949f25 406 Gene3D G3DSA:3.30.200.20 3 116 2.8E-33 T 13-10-2018 CLOST_0387 4ad6922115643bca5f9d5d85a7949f25 406 SUPERFAMILY SSF56112 8 402 1.6E-82 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily CLOST_0387 4ad6922115643bca5f9d5d85a7949f25 406 PIRSF PIRSF031134 2 404 8.0E-144 T 13-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 CLOST_1234 627e21669808e3a398b0a8226382c856 638 Gene3D G3DSA:3.30.590.10 138 495 2.0E-51 T 13-10-2018 CLOST_1234 627e21669808e3a398b0a8226382c856 638 SMART SM01230 135 439 4.5E-37 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CLOST_1234 627e21669808e3a398b0a8226382c856 638 SUPERFAMILY SSF55931 137 535 4.9E-54 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CLOST_1234 627e21669808e3a398b0a8226382c856 638 Pfam PF00120 Glutamine synthetase, catalytic domain 176 445 1.0E-35 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CLOST_0962 2f5c86d3bdbe62ce9ebde8dd6f079f42 378 Gene3D G3DSA:3.30.70.20 317 367 1.8E-12 T 13-10-2018 CLOST_0962 2f5c86d3bdbe62ce9ebde8dd6f079f42 378 Pfam PF04015 Domain of unknown function (DUF362) 41 243 9.2E-40 T 13-10-2018 IPR007160 Domain of unknown function DUF362 CLOST_0962 2f5c86d3bdbe62ce9ebde8dd6f079f42 378 Pfam PF12837 4Fe-4S binding domain 314 337 1.2E-5 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0962 2f5c86d3bdbe62ce9ebde8dd6f079f42 378 SUPERFAMILY SSF54862 302 369 2.79E-18 T 13-10-2018 CLOST_0962 2f5c86d3bdbe62ce9ebde8dd6f079f42 378 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 351 362 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 Gene3D G3DSA:3.30.10.20 662 717 3.9E-6 T 13-10-2018 CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 Gene3D G3DSA:3.30.10.20 594 658 3.7E-6 T 13-10-2018 CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 SUPERFAMILY SSF56519 54 220 6.67E-43 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 SUPERFAMILY SSF56601 171 586 4.13E-106 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 Gene3D G3DSA:3.90.1310.30 49 217 5.3E-47 T 13-10-2018 CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 204 2.1E-24 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 SUPERFAMILY SSF54184 665 714 9.29E-10 T 13-10-2018 CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 Gene3D G3DSA:3.40.710.10 218 580 1.5E-107 T 13-10-2018 CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 Pfam PF03793 PASTA domain 598 658 1.7E-6 T 13-10-2018 IPR005543 PASTA domain CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 Pfam PF03793 PASTA domain 665 711 5.1E-10 T 13-10-2018 IPR005543 PASTA domain CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 Pfam PF00905 Penicillin binding protein transpeptidase domain 247 575 2.0E-83 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 SMART SM00740 594 659 4.8E-8 T 13-10-2018 IPR005543 PASTA domain CLOST_1900 edd272112b9ba0eb227bebb69ebafa22 719 SMART SM00740 661 719 0.0021 T 13-10-2018 IPR005543 PASTA domain CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 TIGRFAM TIGR00016 ackA: acetate kinase 2 396 8.9E-167 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 SUPERFAMILY SSF53067 159 396 1.81E-89 T 13-10-2018 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 Gene3D G3DSA:3.30.420.40 1 196 2.9E-79 T 13-10-2018 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 Gene3D G3DSA:3.30.420.40 197 399 4.4E-83 T 13-10-2018 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 PIRSF PIRSF000722 1 399 9.4E-160 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 Hamap MF_00020 Acetate kinase [ackA]. 1 399 191.02 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 204 221 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 Pfam PF00871 Acetokinase family 3 390 5.9E-167 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 SUPERFAMILY SSF53067 1 197 9.39E-74 T 13-10-2018 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 PRINTS PR00471 Acetate kinase family signature 377 389 3.6E-47 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 PRINTS PR00471 Acetate kinase family signature 204 225 3.6E-47 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 PRINTS PR00471 Acetate kinase family signature 301 314 3.6E-47 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 PRINTS PR00471 Acetate kinase family signature 323 339 3.6E-47 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 PRINTS PR00471 Acetate kinase family signature 3 14 3.6E-47 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1354 42de10b202f3e5828472a4b5f36dab81 399 PRINTS PR00471 Acetate kinase family signature 174 187 3.6E-47 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_1967 18f6f18f7c25ac452b33e3925b751458 122 Pfam PF01638 HxlR-like helix-turn-helix 30 116 1.7E-25 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type CLOST_1967 18f6f18f7c25ac452b33e3925b751458 122 SUPERFAMILY SSF46785 19 118 1.12E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1967 18f6f18f7c25ac452b33e3925b751458 122 Gene3D G3DSA:1.10.10.10 5 120 6.5E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2044 84a9eb3fae6298746221cc21a2d64712 196 Gene3D G3DSA:1.10.357.10 52 196 3.4E-19 T 13-10-2018 CLOST_2044 84a9eb3fae6298746221cc21a2d64712 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 4.8E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_2044 84a9eb3fae6298746221cc21a2d64712 196 SUPERFAMILY SSF46689 3 71 3.49E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_2044 84a9eb3fae6298746221cc21a2d64712 196 Gene3D G3DSA:1.10.10.60 2 51 2.4E-13 T 13-10-2018 CLOST_2044 84a9eb3fae6298746221cc21a2d64712 196 SUPERFAMILY SSF48498 79 195 1.37E-13 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily CLOST_0931 0b6f0f4eaa3f03c83a5d1314f94b2750 309 PIRSF PIRSF010376 20 303 1.3E-82 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CLOST_0931 0b6f0f4eaa3f03c83a5d1314f94b2750 309 SUPERFAMILY SSF55060 181 298 9.11E-20 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CLOST_0931 0b6f0f4eaa3f03c83a5d1314f94b2750 309 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 22 291 1.1E-72 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CLOST_0931 0b6f0f4eaa3f03c83a5d1314f94b2750 309 Gene3D G3DSA:3.30.70.890 178 297 6.6E-22 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CLOST_0931 0b6f0f4eaa3f03c83a5d1314f94b2750 309 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 22 296 30.151 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CLOST_0931 0b6f0f4eaa3f03c83a5d1314f94b2750 309 Gene3D G3DSA:3.30.230.10 13 176 1.9E-55 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_0931 0b6f0f4eaa3f03c83a5d1314f94b2750 309 Pfam PF00288 GHMP kinases N terminal domain 104 162 1.6E-10 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CLOST_0931 0b6f0f4eaa3f03c83a5d1314f94b2750 309 SUPERFAMILY SSF54211 22 174 2.5E-41 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0095 1ad38ff2813bc3fe54f7a3553559c842 604 SMART SM00382 376 561 2.7E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0095 1ad38ff2813bc3fe54f7a3553559c842 604 Pfam PF00005 ABC transporter 367 516 7.0E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0095 1ad38ff2813bc3fe54f7a3553559c842 604 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0095 1ad38ff2813bc3fe54f7a3553559c842 604 Gene3D G3DSA:3.40.50.300 340 595 1.2E-88 T 13-10-2018 CLOST_0095 1ad38ff2813bc3fe54f7a3553559c842 604 Pfam PF00664 ABC transporter transmembrane region 33 303 6.2E-40 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 CLOST_0095 1ad38ff2813bc3fe54f7a3553559c842 604 SUPERFAMILY SSF52540 339 584 4.42E-91 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0095 1ad38ff2813bc3fe54f7a3553559c842 604 Gene3D G3DSA:1.20.1560.10 2 336 9.3E-70 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_0095 1ad38ff2813bc3fe54f7a3553559c842 604 SUPERFAMILY SSF90123 17 336 1.44E-66 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 CLOST_1394 5b30f635b7d6c42f6fcd88b8218f732c 286 Gene3D G3DSA:2.40.10.340 124 279 1.6E-37 T 13-10-2018 CLOST_1394 5b30f635b7d6c42f6fcd88b8218f732c 286 PIRSF PIRSF038471 1 286 2.5E-59 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CLOST_1394 5b30f635b7d6c42f6fcd88b8218f732c 286 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 6 283 4.2E-32 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CLOST_1394 5b30f635b7d6c42f6fcd88b8218f732c 286 Pfam PF04085 rod shape-determining protein MreC 126 280 3.5E-35 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CLOST_1394 5b30f635b7d6c42f6fcd88b8218f732c 286 Gene3D G3DSA:2.40.10.350 183 268 1.6E-37 T 13-10-2018 CLOST_1966 1b8a242ed974884d62d0628fcb9f61a5 264 Gene3D G3DSA:3.10.310.10 4 254 2.3E-90 T 13-10-2018 CLOST_1966 1b8a242ed974884d62d0628fcb9f61a5 264 PIRSF PIRSF016184 1 262 9.9E-56 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CLOST_1966 1b8a242ed974884d62d0628fcb9f61a5 264 Pfam PF02567 Phenazine biosynthesis-like protein 8 253 6.1E-54 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CLOST_1966 1b8a242ed974884d62d0628fcb9f61a5 264 SUPERFAMILY SSF54506 2 260 3.93E-75 T 13-10-2018 CLOST_1966 1b8a242ed974884d62d0628fcb9f61a5 264 Gene3D G3DSA:3.10.310.10 118 250 2.3E-90 T 13-10-2018 CLOST_1966 1b8a242ed974884d62d0628fcb9f61a5 264 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 3 231 2.5E-35 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CLOST_2340 99ef743d946c34078bbddb1abec718cb 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 114 148 3.0E-6 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_2340 99ef743d946c34078bbddb1abec718cb 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 43 72 4.7E-5 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_2340 99ef743d946c34078bbddb1abec718cb 182 SUPERFAMILY SSF51161 29 169 2.77E-35 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_2340 99ef743d946c34078bbddb1abec718cb 182 Gene3D G3DSA:2.160.10.10 8 177 7.4E-37 T 13-10-2018 CLOST_0078 a3da303fb6f96812ad5c29eb928216e0 356 Gene3D G3DSA:3.20.20.210 1 345 1.1E-75 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0078 a3da303fb6f96812ad5c29eb928216e0 356 SUPERFAMILY SSF51726 6 348 9.59E-53 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0078 a3da303fb6f96812ad5c29eb928216e0 356 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 345 4.7E-74 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CLOST_0063 971e49c643734ef8de904b561194edd1 145 SUPERFAMILY SSF55729 1 136 4.78E-22 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0063 971e49c643734ef8de904b561194edd1 145 Gene3D G3DSA:3.40.630.30 10 137 2.3E-21 T 13-10-2018 CLOST_0063 971e49c643734ef8de904b561194edd1 145 Pfam PF00583 Acetyltransferase (GNAT) family 39 132 6.0E-15 T 13-10-2018 IPR000182 GNAT domain CLOST_0523 15ec298dd11b68e866894b8b753f3458 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CLOST_0523 15ec298dd11b68e866894b8b753f3458 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CLOST_0523 15ec298dd11b68e866894b8b753f3458 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 174 1.9E-53 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CLOST_0523 15ec298dd11b68e866894b8b753f3458 194 Gene3D G3DSA:3.30.230.40 3 88 5.5E-24 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 CLOST_0523 15ec298dd11b68e866894b8b753f3458 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 1 192 33.469 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CLOST_0523 15ec298dd11b68e866894b8b753f3458 194 SUPERFAMILY SSF54211 88 178 5.31E-32 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0523 15ec298dd11b68e866894b8b753f3458 194 Gene3D G3DSA:3.30.230.40 90 193 2.4E-34 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 CLOST_0523 15ec298dd11b68e866894b8b753f3458 194 SUPERFAMILY SSF54211 4 85 1.64E-21 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_0248 8c3776fbc8f46ffbf69358692cdfc3e5 294 Gene3D G3DSA:3.40.50.11240 112 292 6.2E-62 T 13-10-2018 CLOST_0248 8c3776fbc8f46ffbf69358692cdfc3e5 294 Gene3D G3DSA:1.10.30.40 44 110 3.4E-25 T 13-10-2018 CLOST_0248 8c3776fbc8f46ffbf69358692cdfc3e5 294 Hamap MF_00601 Ethanolamine ammonia-lyase light chain [eutC]. 57 293 40.626 T 13-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CLOST_0248 8c3776fbc8f46ffbf69358692cdfc3e5 294 PIRSF PIRSF018982 44 294 9.4E-101 T 13-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CLOST_0248 8c3776fbc8f46ffbf69358692cdfc3e5 294 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 65 293 4.1E-83 T 13-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 Pfam PF01872 RibD C-terminal domain 165 377 4.7E-47 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 SUPERFAMILY SSF53597 165 380 3.39E-55 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 164 379 1.7E-63 T 13-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 SUPERFAMILY SSF53927 21 163 6.42E-44 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 Gene3D G3DSA:3.40.140.10 15 158 1.3E-45 T 13-10-2018 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 PIRSF PIRSF006769 16 382 3.7E-132 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 25 376 1.4E-108 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 19 117 1.5E-20 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 Gene3D G3DSA:3.40.430.10 159 381 8.8E-68 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 CLOST_0410 15b8ddbeff4bbb06edec7c42966cc2ee 382 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 68 106 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CLOST_2000 61343c08ab11e602ae8afb0f49ccdec0 205 Pfam PF01184 GPR1/FUN34/yaaH family 12 188 2.7E-19 T 13-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 CLOST_1671 6bb1efef4bb9a9a688b1be58e9195a2c 523 Gene3D G3DSA:3.40.50.1820 97 336 2.6E-23 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold CLOST_1671 6bb1efef4bb9a9a688b1be58e9195a2c 523 SUPERFAMILY SSF53474 147 328 5.35E-23 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold CLOST_1671 6bb1efef4bb9a9a688b1be58e9195a2c 523 Pfam PF01764 Lipase (class 3) 177 326 8.1E-20 T 13-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 CLOST_0767 c12b70253fbfd13ebb05d5031bbff03a 102 SMART SM00418 8 89 3.9E-20 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0767 c12b70253fbfd13ebb05d5031bbff03a 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 1.8E-15 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0767 c12b70253fbfd13ebb05d5031bbff03a 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 40 1.8E-15 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0767 c12b70253fbfd13ebb05d5031bbff03a 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.8E-15 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0767 c12b70253fbfd13ebb05d5031bbff03a 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 1.8E-15 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0767 c12b70253fbfd13ebb05d5031bbff03a 102 Gene3D G3DSA:1.10.10.10 1 93 3.6E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0767 c12b70253fbfd13ebb05d5031bbff03a 102 SUPERFAMILY SSF46785 3 89 1.08E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0767 c12b70253fbfd13ebb05d5031bbff03a 102 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 8.4E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_0366 a7fe68bcda8f539fe3b336f7b8c570e3 215 SUPERFAMILY SSF51161 3 211 4.85E-39 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_0366 a7fe68bcda8f539fe3b336f7b8c570e3 215 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 4 209 2.4E-57 T 13-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CLOST_0366 a7fe68bcda8f539fe3b336f7b8c570e3 215 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 112 145 0.0023 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_0366 a7fe68bcda8f539fe3b336f7b8c570e3 215 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 151 179 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CLOST_0366 a7fe68bcda8f539fe3b336f7b8c570e3 215 Gene3D G3DSA:3.40.50.20 1 93 6.0E-21 T 13-10-2018 CLOST_0366 a7fe68bcda8f539fe3b336f7b8c570e3 215 Gene3D G3DSA:2.160.10.10 95 210 1.2E-27 T 13-10-2018 CLOST_0366 a7fe68bcda8f539fe3b336f7b8c570e3 215 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 161 195 3.0E-8 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_2442 01ba9932024bc57c8b14ab8763dda8e7 409 Pfam PF07690 Major Facilitator Superfamily 23 250 5.2E-27 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOST_2442 01ba9932024bc57c8b14ab8763dda8e7 409 Gene3D G3DSA:1.20.1250.20 3 408 4.0E-55 T 13-10-2018 CLOST_2442 01ba9932024bc57c8b14ab8763dda8e7 409 SUPERFAMILY SSF103473 10 404 1.06E-59 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_1878 611f6006e70f98ab545c9f2190d9639c 261 Gene3D G3DSA:3.30.70.330 88 169 2.2E-19 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily CLOST_1878 611f6006e70f98ab545c9f2190d9639c 261 SUPERFAMILY SSF55174 66 254 1.08E-16 T 13-10-2018 CLOST_2536 dd3c3c503b9a6c15410ca24688f38481 134 Gene3D G3DSA:3.90.1010.20 84 134 1.4E-5 T 13-10-2018 CLOST_2536 dd3c3c503b9a6c15410ca24688f38481 134 Pfam PF04205 FMN-binding domain 67 129 2.1E-9 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOST_2536 dd3c3c503b9a6c15410ca24688f38481 134 SMART SM00900 64 132 1.7E-6 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOST_2525 dbd6701298ea8cb668834fd535fe6662 102 Gene3D G3DSA:1.10.260.40 1 65 3.1E-21 T 13-10-2018 CLOST_2525 dbd6701298ea8cb668834fd535fe6662 102 SMART SM00530 6 61 7.6E-15 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2525 dbd6701298ea8cb668834fd535fe6662 102 SUPERFAMILY SSF47413 2 64 2.45E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_2525 dbd6701298ea8cb668834fd535fe6662 102 Pfam PF01381 Helix-turn-helix 7 61 4.4E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_0251 6ba8ae7d2607c0b02c0542780553e3c5 494 Pfam PF00171 Aldehyde dehydrogenase family 15 275 1.2E-28 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 CLOST_0251 6ba8ae7d2607c0b02c0542780553e3c5 494 TIGRFAM TIGR02518 EutH_ACDH: acetaldehyde dehydrogenase (acetylating) 6 489 1.1E-205 T 13-10-2018 IPR013357 Acetaldehyde dehydrogenase, acetylating CLOST_0251 6ba8ae7d2607c0b02c0542780553e3c5 494 SUPERFAMILY SSF53720 13 449 4.71E-81 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 CLOST_0251 6ba8ae7d2607c0b02c0542780553e3c5 494 Gene3D G3DSA:3.40.605.10 15 445 6.5E-181 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 CLOST_0251 6ba8ae7d2607c0b02c0542780553e3c5 494 Gene3D G3DSA:3.40.309.10 224 408 6.5E-181 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 CLOST_2289 ff5010b5cb3ffd25f0c2ce0af0ba1c2d 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 14 560 4.0E-217 T 13-10-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related CLOST_2289 ff5010b5cb3ffd25f0c2ce0af0ba1c2d 564 SUPERFAMILY SSF55486 33 560 3.45E-115 T 13-10-2018 CLOST_2289 ff5010b5cb3ffd25f0c2ce0af0ba1c2d 564 Pfam PF01432 Peptidase family M3 312 545 5.8E-20 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CLOST_2289 ff5010b5cb3ffd25f0c2ce0af0ba1c2d 564 Gene3D G3DSA:1.10.1370.30 1 564 3.6E-206 T 13-10-2018 CLOST_1098 e52bc570c68bae50613f88756e21edb9 294 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 175 186 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1098 e52bc570c68bae50613f88756e21edb9 294 SUPERFAMILY SSF46548 123 242 6.02E-13 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_1098 e52bc570c68bae50613f88756e21edb9 294 Gene3D G3DSA:3.30.70.20 168 255 3.3E-7 T 13-10-2018 CLOST_1098 e52bc570c68bae50613f88756e21edb9 294 Pfam PF13484 4Fe-4S double cluster binding domain 174 239 1.5E-13 T 13-10-2018 CLOST_1098 e52bc570c68bae50613f88756e21edb9 294 Pfam PF08331 Domain of unknown function (DUF1730) 62 121 3.8E-8 T 13-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PIRSF PIRSF000724 1 398 1.2E-153 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 Pfam PF00162 Phosphoglycerate kinase 9 387 9.8E-167 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 114 129 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 317 342 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 3.1E-93 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 Gene3D G3DSA:3.40.50.1260 174 387 3.8E-168 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 11 397 42.546 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 Gene3D G3DSA:3.40.50.1260 11 395 3.8E-168 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 18 28 - T 13-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0643 6518446ce68b5a03f60dfc4de588be76 398 SUPERFAMILY SSF53748 4 397 7.3E-160 T 13-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_2451 6918dc1d3e69085c19a6f1c2fd7065d4 114 Gene3D G3DSA:3.40.1440.10 19 112 2.4E-11 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 CLOST_2528 5db5dae47ca0f7e045ff0830742b0299 159 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 108 113 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CLOST_2528 5db5dae47ca0f7e045ff0830742b0299 159 Pfam PF04002 RadC-like JAB domain 44 156 5.5E-44 T 13-10-2018 IPR025657 RadC-like JAB domain CLOST_2528 5db5dae47ca0f7e045ff0830742b0299 159 TIGRFAM TIGR00608 radc: DNA repair protein RadC 39 156 1.0E-39 T 13-10-2018 IPR001405 Uncharacterised protein family UPF0758 CLOST_2528 5db5dae47ca0f7e045ff0830742b0299 159 Gene3D G3DSA:3.40.140.10 36 158 3.5E-47 T 13-10-2018 CLOST_2234 3aa685073008be972b7d459fd556fe76 629 TIGRFAM TIGR04480 D_pro_red_PrdA: D-proline reductase (dithiol), PrdA proprotein 4 598 0.0 T 13-10-2018 IPR031002 D-proline reductase, PrdA proprotein GO:0050002|GO:0055114 KEGG: 00330+1.21.4.1 CLOST_2234 3aa685073008be972b7d459fd556fe76 629 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 180 520 5.0E-25 T 13-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 302 3.0E-102 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 Gene3D G3DSA:3.30.479.20 151 284 1.0E-49 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 Gene3D G3DSA:1.10.8.10 1 55 4.6E-26 T 13-10-2018 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 SUPERFAMILY SSF54713 152 303 1.83E-49 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 Hamap MF_00050 Elongation factor Ts [tsf]. 1 302 79.345 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 SUPERFAMILY SSF46934 3 54 3.03E-19 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 Gene3D G3DSA:1.10.286.20 199 243 1.0E-49 T 13-10-2018 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 ProSitePatterns PS01127 Elongation factor Ts signature 2. 76 86 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 SUPERFAMILY SSF54713 55 146 9.03E-22 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 Pfam PF00889 Elongation factor TS 72 285 6.2E-76 T 13-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 CLOST_1704 1ed434570e027e4bde1bd7d6d9453f90 304 Gene3D G3DSA:3.30.479.20 56 149 1.8E-26 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 Gene3D G3DSA:1.20.120.1810 2 117 1.3E-16 T 13-10-2018 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 SUPERFAMILY SSF88659 186 270 1.64E-13 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 SUPERFAMILY SSF88946 30 118 3.3E-26 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 44 267 9.8E-80 T 13-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 Pfam PF04542 Sigma-70 region 2 60 118 7.8E-13 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 Gene3D G3DSA:1.20.140.160 121 270 7.9E-28 T 13-10-2018 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 PRINTS PR00046 Major sigma-70 factor signature 238 253 2.8E-5 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 PRINTS PR00046 Major sigma-70 factor signature 221 233 2.8E-5 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 PRINTS PR00046 Major sigma-70 factor signature 73 86 2.8E-5 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 PRINTS PR00046 Major sigma-70 factor signature 253 264 2.8E-5 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 SUPERFAMILY SSF88659 122 200 6.98E-16 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 Pfam PF04545 Sigma-70, region 4 217 266 2.5E-12 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 266 4.7E-27 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 CLOST_0012 4ef193a9bdf998709d78739267a9be14 273 Pfam PF04539 Sigma-70 region 3 128 191 3.9E-10 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 CLOST_0184 5879510b961dfda62fed60cc890e5026 559 SUPERFAMILY SSF52540 161 553 1.15E-100 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0184 5879510b961dfda62fed60cc890e5026 559 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 378 392 - T 13-10-2018 IPR001482 Type II/IV secretion system protein CLOST_0184 5879510b961dfda62fed60cc890e5026 559 Gene3D G3DSA:3.40.50.300 285 558 2.0E-111 T 13-10-2018 CLOST_0184 5879510b961dfda62fed60cc890e5026 559 SUPERFAMILY SSF160246 2 143 1.29E-41 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily CLOST_0184 5879510b961dfda62fed60cc890e5026 559 Pfam PF00437 Type II/IV secretion system protein 185 450 6.0E-85 T 13-10-2018 IPR001482 Type II/IV secretion system protein CLOST_0184 5879510b961dfda62fed60cc890e5026 559 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 41 146 3.7E-23 T 13-10-2018 IPR007831 General secretory system II, protein E, N-terminal CLOST_0184 5879510b961dfda62fed60cc890e5026 559 Gene3D G3DSA:3.30.300.160 62 143 1.2E-14 T 13-10-2018 CLOST_0184 5879510b961dfda62fed60cc890e5026 559 SMART SM00382 311 432 6.8E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0184 5879510b961dfda62fed60cc890e5026 559 Gene3D G3DSA:3.30.450.90 144 283 2.4E-48 T 13-10-2018 CLOST_2018 478987e1958fcd3876a9ff6082ae3925 178 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 5.5E-10 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_2018 478987e1958fcd3876a9ff6082ae3925 178 Gene3D G3DSA:2.160.10.10 1 172 1.3E-59 T 13-10-2018 CLOST_2018 478987e1958fcd3876a9ff6082ae3925 178 SUPERFAMILY SSF51161 3 165 9.84E-47 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_1186 2e180361eed9b6a1199a78704b2a4dd0 105 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 2 100 3.8E-24 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like CLOST_2197 c52c4d54810557dee2a29e629b7f4903 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.626 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2197 c52c4d54810557dee2a29e629b7f4903 207 Gene3D G3DSA:3.40.1370.10 3 207 2.6E-80 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2197 c52c4d54810557dee2a29e629b7f4903 207 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 1.6E-72 T 13-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CLOST_2197 c52c4d54810557dee2a29e629b7f4903 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 204 3.9E-80 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2197 c52c4d54810557dee2a29e629b7f4903 207 SUPERFAMILY SSF52166 1 206 5.1E-81 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 CLOST_2403 43538613454dc13cc6d0b2c5ceaca8b2 276 SUPERFAMILY SSF82549 2 276 3.92E-66 T 13-10-2018 CLOST_2403 43538613454dc13cc6d0b2c5ceaca8b2 276 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 1 275 3.6E-64 T 13-10-2018 IPR003797 DegV CLOST_2403 43538613454dc13cc6d0b2c5ceaca8b2 276 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 275 2.9E-61 T 13-10-2018 IPR003797 DegV CLOST_2403 43538613454dc13cc6d0b2c5ceaca8b2 276 Gene3D G3DSA:3.40.50.10440 2 144 3.9E-42 T 13-10-2018 CLOST_2403 43538613454dc13cc6d0b2c5ceaca8b2 276 Gene3D G3DSA:2.20.28.50 25 62 3.9E-42 T 13-10-2018 CLOST_2403 43538613454dc13cc6d0b2c5ceaca8b2 276 Gene3D G3DSA:3.30.1180.10 150 276 2.5E-42 T 13-10-2018 CLOST_1119 a02a0b0ba5e023658cd49c3eabe6b11d 279 ProSitePatterns PS00211 ABC transporters family signature. 179 193 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1119 a02a0b0ba5e023658cd49c3eabe6b11d 279 SUPERFAMILY SSF52540 33 267 2.07E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1119 a02a0b0ba5e023658cd49c3eabe6b11d 279 Gene3D G3DSA:3.40.50.300 31 273 4.7E-41 T 13-10-2018 CLOST_1119 a02a0b0ba5e023658cd49c3eabe6b11d 279 Pfam PF00005 ABC transporter 50 206 1.3E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0276 dac8f2d12499cf859eb8a5d4e7437cf5 223 SUPERFAMILY SSF63380 7 73 2.33E-16 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CLOST_0276 dac8f2d12499cf859eb8a5d4e7437cf5 223 PIRSF PIRSF006816 1 221 7.5E-57 T 13-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CLOST_0276 dac8f2d12499cf859eb8a5d4e7437cf5 223 SUPERFAMILY SSF52343 68 214 2.62E-19 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CLOST_0276 dac8f2d12499cf859eb8a5d4e7437cf5 223 Gene3D G3DSA:3.40.50.80 77 177 1.3E-10 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CLOST_0276 dac8f2d12499cf859eb8a5d4e7437cf5 223 Gene3D G3DSA:2.10.240.10 178 216 4.5E-12 T 13-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily CLOST_0276 dac8f2d12499cf859eb8a5d4e7437cf5 223 Gene3D G3DSA:2.40.30.10 1 71 6.8E-18 T 13-10-2018 CLOST_0276 dac8f2d12499cf859eb8a5d4e7437cf5 223 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 178 214 2.0E-14 T 13-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CLOST_0583 7b54d7dd3c3829dc80ff0204a2ffb34d 345 Gene3D G3DSA:3.40.50.300 6 332 1.1E-98 T 13-10-2018 CLOST_0583 7b54d7dd3c3829dc80ff0204a2ffb34d 345 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0583 7b54d7dd3c3829dc80ff0204a2ffb34d 345 SUPERFAMILY SSF52540 36 323 4.48E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0583 7b54d7dd3c3829dc80ff0204a2ffb34d 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 304 3.3E-20 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0583 7b54d7dd3c3829dc80ff0204a2ffb34d 345 Pfam PF00005 ABC transporter 29 186 2.1E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0583 7b54d7dd3c3829dc80ff0204a2ffb34d 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 324 1.5E-27 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0583 7b54d7dd3c3829dc80ff0204a2ffb34d 345 SMART SM00382 37 244 1.7E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2437 848191e4da51bb98b8c48e116ee25e24 667 Gene3D G3DSA:1.10.287.950 416 666 1.6E-57 T 13-10-2018 CLOST_2437 848191e4da51bb98b8c48e116ee25e24 667 SUPERFAMILY SSF58104 335 666 4.97E-63 T 13-10-2018 CLOST_2437 848191e4da51bb98b8c48e116ee25e24 667 Pfam PF02743 Cache domain 36 265 6.5E-26 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_2437 848191e4da51bb98b8c48e116ee25e24 667 Gene3D G3DSA:3.30.450.20 138 268 3.7E-24 T 13-10-2018 CLOST_2437 848191e4da51bb98b8c48e116ee25e24 667 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 469 618 4.0E-35 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2437 848191e4da51bb98b8c48e116ee25e24 667 SMART SM00283 391 666 1.2E-51 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2437 848191e4da51bb98b8c48e116ee25e24 667 Gene3D G3DSA:1.20.1480.50 269 369 4.8E-10 T 13-10-2018 CLOST_1242 5138d2e6b2e13869f0017f7928a8af7a 304 Pfam PF07728 AAA domain (dynein-related subfamily) 60 192 1.7E-20 T 13-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CLOST_1242 5138d2e6b2e13869f0017f7928a8af7a 304 SUPERFAMILY SSF52540 48 260 3.87E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1242 5138d2e6b2e13869f0017f7928a8af7a 304 Gene3D G3DSA:3.40.50.300 45 210 3.0E-30 T 13-10-2018 CLOST_1823 8e59ed718a07d25ba676be8b39717ba1 305 Hamap MF_00313 Glutaminase [glsA]. 1 305 44.526 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CLOST_1823 8e59ed718a07d25ba676be8b39717ba1 305 Gene3D G3DSA:3.40.710.10 1 305 4.7E-115 T 13-10-2018 CLOST_1823 8e59ed718a07d25ba676be8b39717ba1 305 SUPERFAMILY SSF56601 2 305 1.55E-109 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like CLOST_1823 8e59ed718a07d25ba676be8b39717ba1 305 TIGRFAM TIGR03814 Gln_ase: glutaminase A 5 305 5.5E-119 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CLOST_1823 8e59ed718a07d25ba676be8b39717ba1 305 Pfam PF04960 Glutaminase 19 305 1.9E-114 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CLOST_0641 58f8ba24d506994d02d7d97023cea8fa 346 Gene3D G3DSA:3.40.50.1360 91 338 3.3E-72 T 13-10-2018 CLOST_0641 58f8ba24d506994d02d7d97023cea8fa 346 SUPERFAMILY SSF100950 90 337 1.58E-61 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_0641 58f8ba24d506994d02d7d97023cea8fa 346 Pfam PF04198 Putative sugar-binding domain 90 337 2.0E-58 T 13-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CLOST_0641 58f8ba24d506994d02d7d97023cea8fa 346 SUPERFAMILY SSF46785 19 84 5.45E-12 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0641 58f8ba24d506994d02d7d97023cea8fa 346 Gene3D G3DSA:1.10.10.10 17 90 2.9E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 Gene3D G3DSA:3.30.1360.10 14 219 6.6E-86 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 238 303 1.6E-28 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 4.2E-23 T 13-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 36.961 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 251 309 3.0E-22 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 Gene3D G3DSA:1.10.150.20 235 312 1.8E-33 T 13-10-2018 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 18 309 1.6E-119 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 SUPERFAMILY SSF55257 4 224 1.86E-30 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 Gene3D G3DSA:2.170.120.12 48 168 6.6E-86 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 SMART SM00662 18 225 4.0E-91 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 SUPERFAMILY SSF47789 246 309 1.44E-24 T 13-10-2018 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 SUPERFAMILY SSF56553 48 169 1.03E-43 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_2170 86caba28c4958cc3d1a366b0410f2efe 313 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 219 7.9E-22 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CLOST_1292 fcaca9932fb2ad6ad14691c7fae7f6f2 469 Gene3D G3DSA:3.40.50.1100 99 212 7.7E-43 T 13-10-2018 CLOST_1292 fcaca9932fb2ad6ad14691c7fae7f6f2 469 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 365 3.2E-53 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_1292 fcaca9932fb2ad6ad14691c7fae7f6f2 469 Gene3D G3DSA:3.40.50.1100 61 365 7.7E-43 T 13-10-2018 CLOST_1292 fcaca9932fb2ad6ad14691c7fae7f6f2 469 SUPERFAMILY SSF53686 41 366 3.01E-54 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_2033 0ed9b3ed7913fb7cd4e4fd4cdc40b9dd 227 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 79 201 2.3E-12 T 13-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CLOST_2033 0ed9b3ed7913fb7cd4e4fd4cdc40b9dd 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 1.5E-25 T 13-10-2018 CLOST_2033 0ed9b3ed7913fb7cd4e4fd4cdc40b9dd 227 Gene3D G3DSA:3.40.50.1000 5 222 1.4E-70 T 13-10-2018 IPR023214 HAD superfamily CLOST_2033 0ed9b3ed7913fb7cd4e4fd4cdc40b9dd 227 Gene3D G3DSA:1.10.150.240 16 100 1.4E-70 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 CLOST_2033 0ed9b3ed7913fb7cd4e4fd4cdc40b9dd 227 SUPERFAMILY SSF56784 2 227 6.34E-44 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_2033 0ed9b3ed7913fb7cd4e4fd4cdc40b9dd 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 114 194 8.2E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CLOST_2033 0ed9b3ed7913fb7cd4e4fd4cdc40b9dd 227 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 226 4.3E-68 T 13-10-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CLOST_0515 64e23d98f781038543725d1e3217e329 438 Gene3D G3DSA:3.30.565.10 294 437 5.8E-12 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0515 64e23d98f781038543725d1e3217e329 438 Pfam PF14501 GHKL domain 338 435 3.0E-17 T 13-10-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CLOST_0515 64e23d98f781038543725d1e3217e329 438 SUPERFAMILY SSF55874 303 430 4.35E-7 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 Pfam PF01380 SIS domain 461 590 8.8E-29 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 Pfam PF01380 SIS domain 289 415 1.7E-32 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 608 3.7E-252 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 Gene3D G3DSA:3.60.20.10 2 240 6.7E-77 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 Gene3D G3DSA:3.40.50.10490 446 593 1.8E-151 T 13-10-2018 CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 Gene3D G3DSA:3.40.50.10490 246 607 1.8E-151 T 13-10-2018 CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 Pfam PF13522 Glutamine amidotransferase domain 64 189 2.8E-21 T 13-10-2018 CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 608 40.986 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 SUPERFAMILY SSF56235 2 233 1.29E-70 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CLOST_0498 2a1686569501156bcfebd8cc3c40b8b1 608 SUPERFAMILY SSF53697 245 608 1.11E-115 T 13-10-2018 CLOST_1685 8fed6a5983527afc44a662c63f518950 87 SUPERFAMILY SSF47060 2 87 2.33E-36 T 13-10-2018 IPR009068 S15/NS1, RNA-binding CLOST_1685 8fed6a5983527afc44a662c63f518950 87 ProSitePatterns PS00362 Ribosomal protein S15 signature. 37 67 - T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1685 8fed6a5983527afc44a662c63f518950 87 Gene3D G3DSA:1.10.287.10 1 87 6.8E-36 T 13-10-2018 CLOST_1685 8fed6a5983527afc44a662c63f518950 87 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 3 87 1.7E-40 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1685 8fed6a5983527afc44a662c63f518950 87 Pfam PF00312 Ribosomal protein S15 6 86 2.3E-38 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1685 8fed6a5983527afc44a662c63f518950 87 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 87 22.783 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1685 8fed6a5983527afc44a662c63f518950 87 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 8 86 1.0E-28 T 13-10-2018 CLOST_1685 8fed6a5983527afc44a662c63f518950 87 SMART SM01387 6 86 3.9E-54 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 Pfam PF00696 Amino acid kinase family 28 263 7.5E-48 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 261 3.4E-79 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 SUPERFAMILY SSF53633 6 285 2.75E-88 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 PIRSF PIRSF000728 12 286 1.3E-108 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 Hamap MF_00082 Acetylglutamate kinase [argB]. 26 279 47.81 T 13-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 PRINTS PR00474 Glutamate 5-kinase family signature 58 72 9.8E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 PRINTS PR00474 Glutamate 5-kinase family signature 183 210 9.8E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 PRINTS PR00474 Glutamate 5-kinase family signature 236 256 9.8E-7 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CLOST_0137 2de526a24eb2e1e60ed6b2f5126fb750 286 Gene3D G3DSA:3.40.1160.10 3 286 1.9E-95 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CLOST_0719 fd4c56c880355d3d214792c1bb499da1 428 Pfam PF13530 Sterol carrier protein domain 187 423 1.3E-25 T 13-10-2018 IPR025559 Enhanced intracellular survival protein domain CLOST_0719 fd4c56c880355d3d214792c1bb499da1 428 Pfam PF13527 Acetyltransferase (GNAT) domain 9 141 3.7E-18 T 13-10-2018 CLOST_0719 fd4c56c880355d3d214792c1bb499da1 428 Gene3D G3DSA:3.40.630.30 146 296 7.3E-12 T 13-10-2018 CLOST_0719 fd4c56c880355d3d214792c1bb499da1 428 SUPERFAMILY SSF55729 8 281 2.61E-32 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0719 fd4c56c880355d3d214792c1bb499da1 428 Gene3D G3DSA:3.30.1050.10 298 419 3.5E-6 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily CLOST_0719 fd4c56c880355d3d214792c1bb499da1 428 Gene3D G3DSA:3.40.630.30 2 145 3.1E-24 T 13-10-2018 CLOST_0719 fd4c56c880355d3d214792c1bb499da1 428 SUPERFAMILY SSF55718 312 420 4.71E-8 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily CLOST_2029 ff2f3b6057f3ba3e5626fec8de09ca28 339 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 305 316 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2029 ff2f3b6057f3ba3e5626fec8de09ca28 339 Pfam PF17179 4Fe-4S dicluster domain 223 319 1.6E-32 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2029 ff2f3b6057f3ba3e5626fec8de09ca28 339 Gene3D G3DSA:1.10.1060.10 276 333 1.4E-5 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_2029 ff2f3b6057f3ba3e5626fec8de09ca28 339 SUPERFAMILY SSF46548 215 330 1.74E-13 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_2029 ff2f3b6057f3ba3e5626fec8de09ca28 339 TIGRFAM TIGR02910 sulfite_red_A: sulfite reductase, subunit A 1 334 1.5E-145 T 13-10-2018 IPR014259 Sulphite reductase, subunit A CLOST_2029 ff2f3b6057f3ba3e5626fec8de09ca28 339 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 224 235 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 Pfam PF13416 Bacterial extracellular solute-binding protein 54 321 3.6E-32 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 Gene3D G3DSA:3.40.190.10 42 318 3.2E-74 T 13-10-2018 CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 SUPERFAMILY SSF53850 39 353 3.86E-65 T 13-10-2018 CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 60 81 1.2E-17 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 1.2E-17 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 44 60 1.2E-17 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 155 169 1.2E-17 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 173 192 1.2E-17 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 256 275 1.2E-17 T 13-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CLOST_1204 de9e75deb55c9408eda3379b5258c5b1 354 Gene3D G3DSA:3.40.190.10 140 347 3.2E-74 T 13-10-2018 CLOST_0948 8428235983969ec31dc3dbbf021bc8c7 194 Pfam PF12822 ECF transporter, substrate-specific component 12 183 1.4E-33 T 13-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CLOST_0948 8428235983969ec31dc3dbbf021bc8c7 194 Gene3D G3DSA:1.10.1760.20 6 194 6.0E-63 T 13-10-2018 CLOST_0115 3429b8d766081d31c1c35372c9229f20 187 SUPERFAMILY SSF50475 1 176 2.14E-38 T 13-10-2018 CLOST_0115 3429b8d766081d31c1c35372c9229f20 187 Gene3D G3DSA:2.30.110.10 1 178 2.3E-40 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 CLOST_0115 3429b8d766081d31c1c35372c9229f20 187 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 13 171 9.1E-20 T 13-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CLOST_0503 295f696be1ee279fcb491299b93088b5 179 Pfam PF11181 Heat induced stress protein YflT 7 61 3.1E-10 T 13-10-2018 IPR025889 General stress protein 17M-like domain CLOST_0762 c1cf41624ce58e75ffc2eb61df1b53ec 75 Gene3D G3DSA:3.40.30.10 1 75 5.7E-31 T 13-10-2018 CLOST_0762 c1cf41624ce58e75ffc2eb61df1b53ec 75 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 75 4.9E-25 T 13-10-2018 IPR005243 Redox-active disulphide protein 2 CLOST_0762 c1cf41624ce58e75ffc2eb61df1b53ec 75 Pfam PF13192 Thioredoxin domain 1 75 2.6E-27 T 13-10-2018 IPR012336 Thioredoxin-like fold CLOST_0762 c1cf41624ce58e75ffc2eb61df1b53ec 75 PIRSF PIRSF037031 1 75 1.0E-32 T 13-10-2018 IPR005243 Redox-active disulphide protein 2 CLOST_0762 c1cf41624ce58e75ffc2eb61df1b53ec 75 SUPERFAMILY SSF52833 1 75 4.86E-19 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_0345 cc82c1b23db4cd370c8c5e54284f97d5 304 Pfam PF02541 Ppx/GppA phosphatase family 30 301 2.3E-62 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CLOST_0345 cc82c1b23db4cd370c8c5e54284f97d5 304 SUPERFAMILY SSF53067 2 120 7.25E-31 T 13-10-2018 CLOST_0345 cc82c1b23db4cd370c8c5e54284f97d5 304 Gene3D G3DSA:3.30.420.40 1 122 1.2E-37 T 13-10-2018 CLOST_0345 cc82c1b23db4cd370c8c5e54284f97d5 304 Gene3D G3DSA:3.30.420.150 123 303 5.6E-55 T 13-10-2018 CLOST_0345 cc82c1b23db4cd370c8c5e54284f97d5 304 SUPERFAMILY SSF53067 125 300 4.28E-39 T 13-10-2018 CLOST_2051 e21ba3d9b6248da451fb225c4ec66f01 332 SUPERFAMILY SSF52172 1 132 1.42E-37 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_2051 e21ba3d9b6248da451fb225c4ec66f01 332 Pfam PF00072 Response regulator receiver domain 3 113 3.3E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2051 e21ba3d9b6248da451fb225c4ec66f01 332 Gene3D G3DSA:1.10.3210.10 127 332 1.9E-72 T 13-10-2018 CLOST_2051 e21ba3d9b6248da451fb225c4ec66f01 332 SUPERFAMILY SSF109604 122 319 3.45E-35 T 13-10-2018 CLOST_2051 e21ba3d9b6248da451fb225c4ec66f01 332 Gene3D G3DSA:3.40.50.2300 1 126 6.4E-36 T 13-10-2018 CLOST_2051 e21ba3d9b6248da451fb225c4ec66f01 332 SMART SM00448 1 114 3.7E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2051 e21ba3d9b6248da451fb225c4ec66f01 332 Pfam PF13487 HD domain 204 271 6.6E-16 T 13-10-2018 CLOST_2051 e21ba3d9b6248da451fb225c4ec66f01 332 SMART SM00471 140 290 5.6E-5 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0109 2959b4ae4ec4f09a229a7681cf22160b 115 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 14 108 22.944 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CLOST_0109 2959b4ae4ec4f09a229a7681cf22160b 115 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 14 114 8.3E-31 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CLOST_0109 2959b4ae4ec4f09a229a7681cf22160b 115 Pfam PF02575 YbaB/EbfC DNA-binding family 20 110 3.0E-34 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CLOST_0109 2959b4ae4ec4f09a229a7681cf22160b 115 SUPERFAMILY SSF82607 20 114 2.49E-32 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily CLOST_0109 2959b4ae4ec4f09a229a7681cf22160b 115 Gene3D G3DSA:3.30.1310.10 10 115 9.5E-39 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily CLOST_0109 2959b4ae4ec4f09a229a7681cf22160b 115 PIRSF PIRSF004555 12 115 6.1E-39 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CLOST_0661 e5ecf87b4f047ecb6e2b1f2461c89315 575 SUPERFAMILY SSF52540 237 477 8.84E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0661 e5ecf87b4f047ecb6e2b1f2461c89315 575 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 262 275 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CLOST_0661 e5ecf87b4f047ecb6e2b1f2461c89315 575 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 325 340 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOST_0661 e5ecf87b4f047ecb6e2b1f2461c89315 575 Gene3D G3DSA:1.10.8.60 411 481 5.3E-15 T 13-10-2018 CLOST_0661 e5ecf87b4f047ecb6e2b1f2461c89315 575 Gene3D G3DSA:3.40.50.300 228 410 2.1E-61 T 13-10-2018 CLOST_0661 e5ecf87b4f047ecb6e2b1f2461c89315 575 Pfam PF00158 Sigma-54 interaction domain 239 402 5.5E-67 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOST_0661 e5ecf87b4f047ecb6e2b1f2461c89315 575 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 448 457 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site CLOST_0661 e5ecf87b4f047ecb6e2b1f2461c89315 575 SMART SM00382 258 406 2.5E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1103 7d9b3a8669deb61c80f60969d36ba3f3 201 SMART SM00855 3 153 3.6E-12 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CLOST_1103 7d9b3a8669deb61c80f60969d36ba3f3 201 SUPERFAMILY SSF53254 1 197 9.11E-54 T 13-10-2018 IPR029033 Histidine phosphatase superfamily CLOST_1103 7d9b3a8669deb61c80f60969d36ba3f3 201 Gene3D G3DSA:3.40.50.1240 1 200 1.1E-55 T 13-10-2018 IPR029033 Histidine phosphatase superfamily CLOST_1103 7d9b3a8669deb61c80f60969d36ba3f3 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 193 2.3E-50 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CLOST_1103 7d9b3a8669deb61c80f60969d36ba3f3 201 PIRSF PIRSF000709 2 189 1.4E-19 T 13-10-2018 CLOST_0228 ff764958e17fa2ccc52b19fb105cb24e 386 Pfam PF05684 Protein of unknown function (DUF819) 10 386 2.8E-113 T 13-10-2018 IPR008537 Protein of unknown function DUF819 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 1.6E-30 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 1.6E-30 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 1.6E-30 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 1.6E-30 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 1.6E-30 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 1.6E-30 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 25.984 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 Pfam PF00342 Phosphoglucose isomerase 76 426 3.1E-27 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 Gene3D G3DSA:3.40.50.10490 39 225 1.4E-73 T 13-10-2018 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 Gene3D G3DSA:3.40.50.10490 226 417 5.7E-75 T 13-10-2018 CLOST_0601 c40352036ad416bd21a42bf693f212aa 453 SUPERFAMILY SSF53697 5 446 4.89E-133 T 13-10-2018 CLOST_2474 c9d16d8c9f750cae402c0c61f2a1d150 400 PIRSF PIRSF004810 1 400 6.3E-70 T 13-10-2018 IPR014047 Chromate transporter, long chain CLOST_2474 c9d16d8c9f750cae402c0c61f2a1d150 400 TIGRFAM TIGR00937 2A51: chromate efflux transporter 29 397 9.1E-59 T 13-10-2018 IPR014047 Chromate transporter, long chain CLOST_2474 c9d16d8c9f750cae402c0c61f2a1d150 400 Pfam PF02417 Chromate transporter 23 182 8.8E-22 T 13-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CLOST_2474 c9d16d8c9f750cae402c0c61f2a1d150 400 Pfam PF02417 Chromate transporter 228 397 1.3E-33 T 13-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CLOST_0772 546210441b5039466412a6242371b3f8 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 306 3.2E-45 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_0772 546210441b5039466412a6242371b3f8 332 SUPERFAMILY SSF81345 19 226 1.57E-5 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_0940 9e6aebb16fbb697e16624382cc3e11fb 310 SMART SM00382 42 186 2.3E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0940 9e6aebb16fbb697e16624382cc3e11fb 310 SUPERFAMILY SSF52540 2 292 2.7E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0940 9e6aebb16fbb697e16624382cc3e11fb 310 Gene3D G3DSA:3.40.50.300 42 246 6.1E-83 T 13-10-2018 CLOST_0940 9e6aebb16fbb697e16624382cc3e11fb 310 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 10 305 2.6E-104 T 13-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CLOST_0940 9e6aebb16fbb697e16624382cc3e11fb 310 Pfam PF03308 ArgK protein 16 274 2.9E-92 T 13-10-2018 CLOST_2458 5010af28c6e298813a81756a1f2a0540 148 SUPERFAMILY SSF51316 14 147 8.89E-58 T 13-10-2018 IPR011057 Mss4-like superfamily CLOST_2458 5010af28c6e298813a81756a1f2a0540 148 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 16 142 2.0E-58 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CLOST_2458 5010af28c6e298813a81756a1f2a0540 148 Gene3D G3DSA:2.170.150.20 8 148 1.1E-54 T 13-10-2018 CLOST_2458 5010af28c6e298813a81756a1f2a0540 148 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 134 36.637 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CLOST_2458 5010af28c6e298813a81756a1f2a0540 148 Pfam PF01641 SelR domain 17 133 2.5E-46 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CLOST_1062 8440494731fe36871d91dd9aadac438f 47 Pfam PF12669 Virus attachment protein p12 family 2 42 2.7E-8 T 13-10-2018 CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 SUPERFAMILY SSF46548 251 328 1.23E-9 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 PRINTS PR00069 Aldo-keto reductase signature 36 60 1.2E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 PRINTS PR00069 Aldo-keto reductase signature 88 106 1.2E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 PRINTS PR00069 Aldo-keto reductase signature 124 141 1.2E-5 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 304 315 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 Pfam PF00248 Aldo/keto reductase family 14 196 1.2E-30 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 SUPERFAMILY SSF51430 2 276 3.54E-55 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 Pfam PF13534 4Fe-4S dicluster domain 255 318 8.6E-12 T 13-10-2018 CLOST_1646 aafcc2b11b467c4aaca4ed194cddbe94 334 Gene3D G3DSA:3.20.20.100 2 233 1.2E-54 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily CLOST_2488 3fc0aaf380125967ffedff169ad7a660 243 Pfam PF01061 ABC-2 type transporter 1 204 5.2E-26 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CLOST_2488 3fc0aaf380125967ffedff169ad7a660 243 PRINTS PR00164 ABC-2 type transport system membrane protein signature 166 185 4.0E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_2488 3fc0aaf380125967ffedff169ad7a660 243 PRINTS PR00164 ABC-2 type transport system membrane protein signature 129 153 4.0E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_2488 3fc0aaf380125967ffedff169ad7a660 243 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 4.0E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_2488 3fc0aaf380125967ffedff169ad7a660 243 PRINTS PR00164 ABC-2 type transport system membrane protein signature 16 37 4.0E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_2488 3fc0aaf380125967ffedff169ad7a660 243 PIRSF PIRSF006648 1 243 2.7E-17 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_0397 5af9dd383d38536925d6d882107c3fbb 357 Pfam PF09992 Phosphodiester glycosidase 184 356 5.9E-23 T 13-10-2018 IPR018711 Phosphodiester glycosidase CLOST_2453 f51be3ed88b1da60aca42a9349991fd3 114 SUPERFAMILY SSF88874 27 88 1.31E-24 T 13-10-2018 CLOST_2453 f51be3ed88b1da60aca42a9349991fd3 114 Pfam PF07484 Phage Tail Collar Domain 35 90 5.3E-25 T 13-10-2018 IPR011083 Phage tail collar domain CLOST_2453 f51be3ed88b1da60aca42a9349991fd3 114 Gene3D G3DSA:3.90.1340.10 22 87 3.5E-16 T 13-10-2018 IPR037053 Phage tail collar domain superfamily CLOST_1759 469f2cd78c72987bb4ded3a2b8b4f719 123 SMART SM00905 4 117 2.0E-44 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CLOST_1759 469f2cd78c72987bb4ded3a2b8b4f719 123 SUPERFAMILY SSF55620 2 119 1.73E-35 T 13-10-2018 CLOST_1759 469f2cd78c72987bb4ded3a2b8b4f719 123 Pfam PF02152 Dihydroneopterin aldolase 4 116 1.1E-31 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CLOST_1759 469f2cd78c72987bb4ded3a2b8b4f719 123 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 4.3E-33 T 13-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CLOST_1759 469f2cd78c72987bb4ded3a2b8b4f719 123 TIGRFAM TIGR00526 folB_dom: FolB domain 1 120 2.2E-29 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CLOST_1759 469f2cd78c72987bb4ded3a2b8b4f719 123 Gene3D G3DSA:3.30.1130.10 1 122 3.7E-41 T 13-10-2018 CLOST_2586 4315c0790261a450e5bef68a680df007 208 Pfam PF01424 R3H domain 148 204 2.5E-15 T 13-10-2018 IPR001374 R3H domain GO:0003676 CLOST_2586 4315c0790261a450e5bef68a680df007 208 Pfam PF13083 KH domain 66 133 2.3E-12 T 13-10-2018 CLOST_2586 4315c0790261a450e5bef68a680df007 208 Pfam PF14804 Jag N-terminus 8 56 8.3E-21 T 13-10-2018 IPR032782 Jag, N-terminal CLOST_2586 4315c0790261a450e5bef68a680df007 208 SMART SM00393 128 207 1.5E-19 T 13-10-2018 IPR001374 R3H domain GO:0003676 CLOST_2586 4315c0790261a450e5bef68a680df007 208 Gene3D G3DSA:3.30.1370.50 143 208 3.2E-28 T 13-10-2018 IPR036867 R3H domain superfamily GO:0003676 CLOST_2586 4315c0790261a450e5bef68a680df007 208 Gene3D G3DSA:3.30.300.20 60 142 4.1E-23 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta CLOST_2586 4315c0790261a450e5bef68a680df007 208 Gene3D G3DSA:3.30.30.80 1 56 5.8E-19 T 13-10-2018 IPR038247 Jag, N-terminal domain superfamily CLOST_2586 4315c0790261a450e5bef68a680df007 208 SMART SM01245 5 57 9.8E-23 T 13-10-2018 IPR032782 Jag, N-terminal CLOST_2586 4315c0790261a450e5bef68a680df007 208 SUPERFAMILY SSF82708 154 205 2.35E-8 T 13-10-2018 IPR036867 R3H domain superfamily GO:0003676 CLOST_0374 d2c0c6ea2970fbd3a2be90df36f66059 224 SUPERFAMILY SSF46785 144 215 3.27E-8 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0374 d2c0c6ea2970fbd3a2be90df36f66059 224 Gene3D G3DSA:2.60.120.10 16 140 6.9E-23 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0374 d2c0c6ea2970fbd3a2be90df36f66059 224 Pfam PF13545 Crp-like helix-turn-helix domain 149 216 1.5E-9 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_0374 d2c0c6ea2970fbd3a2be90df36f66059 224 SUPERFAMILY SSF51206 23 137 8.25E-25 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like CLOST_0374 d2c0c6ea2970fbd3a2be90df36f66059 224 Gene3D G3DSA:1.10.10.10 144 217 1.9E-9 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0374 d2c0c6ea2970fbd3a2be90df36f66059 224 Pfam PF00027 Cyclic nucleotide-binding domain 30 115 5.3E-14 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_2560 e7d3ff643f62c45a449986d0d522cde0 255 Gene3D G3DSA:1.20.1080.10 1 255 3.0E-79 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CLOST_2560 e7d3ff643f62c45a449986d0d522cde0 255 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 76 85 - T 13-10-2018 IPR024002 Formate/nitrite transporter, conserved site CLOST_2560 e7d3ff643f62c45a449986d0d522cde0 255 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 159 169 - T 13-10-2018 IPR024002 Formate/nitrite transporter, conserved site CLOST_2560 e7d3ff643f62c45a449986d0d522cde0 255 Pfam PF01226 Formate/nitrite transporter 10 250 1.3E-63 T 13-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 CLOST_0150 0bb9ef034749b440fb7f0453ce252a00 230 SUPERFAMILY SSF51412 67 207 6.96E-14 T 13-10-2018 CLOST_0150 0bb9ef034749b440fb7f0453ce252a00 230 Gene3D G3DSA:3.20.20.70 8 227 1.3E-12 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1056 1e0b2986ac4106217e2ecb60807968b8 441 PIRSF PIRSF011588 1 441 5.3E-182 T 13-10-2018 IPR016585 Glycine/sarcosine/betaine reductase, component B, fused alpha/beta GO:0050485|GO:0055114 CLOST_1056 1e0b2986ac4106217e2ecb60807968b8 441 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 1 438 1.4E-187 T 13-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CLOST_1880 231f7fe31c560f72fda0a9c1f052679d 147 Gene3D G3DSA:3.30.110.150 53 147 1.2E-30 T 13-10-2018 IPR038594 SepF-like superfamily CLOST_1880 231f7fe31c560f72fda0a9c1f052679d 147 Pfam PF04472 Cell division protein SepF 59 131 1.8E-24 T 13-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CLOST_1880 231f7fe31c560f72fda0a9c1f052679d 147 Hamap MF_01197 Cell division protein SepF [sepF]. 3 139 14.597 T 13-10-2018 IPR023052 Cell division protein SepF GO:0090529 CLOST_1997 9a4b8ac6088e7d5b7bcdb3b88ecd1edc 300 Hamap MF_00548 Zinc transporter ZupT [zupT]. 4 300 36.495 T 13-10-2018 IPR023498 Zinc transporter ZupT CLOST_1997 9a4b8ac6088e7d5b7bcdb3b88ecd1edc 300 SUPERFAMILY SSF103473 8 297 3.66E-5 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_1997 9a4b8ac6088e7d5b7bcdb3b88ecd1edc 300 Pfam PF02535 ZIP Zinc transporter 97 294 6.9E-32 T 13-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CLOST_2192 30a9c220c37dff23690253d64694c128 263 SUPERFAMILY SSF54821 107 206 1.16E-38 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2192 30a9c220c37dff23690253d64694c128 263 SMART SM00322 60 125 2.9E-6 T 13-10-2018 IPR004087 K Homology domain GO:0003676 CLOST_2192 30a9c220c37dff23690253d64694c128 263 SUPERFAMILY SSF54814 2 106 5.98E-38 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CLOST_2192 30a9c220c37dff23690253d64694c128 263 Pfam PF07650 KH domain 38 110 4.9E-17 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2192 30a9c220c37dff23690253d64694c128 263 Gene3D G3DSA:3.30.300.20 17 107 1.0E-30 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta CLOST_2192 30a9c220c37dff23690253d64694c128 263 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.8E-93 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CLOST_2192 30a9c220c37dff23690253d64694c128 263 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 13-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2192 30a9c220c37dff23690253d64694c128 263 Gene3D G3DSA:3.30.1140.32 108 208 2.1E-41 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2192 30a9c220c37dff23690253d64694c128 263 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 5.3E-40 T 13-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2192 30a9c220c37dff23690253d64694c128 263 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.137 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CLOST_1324 79ee626b85602b69384325aac8bdaa61 134 Pfam PF13380 CoA binding domain 14 127 1.7E-28 T 13-10-2018 IPR003781 CoA-binding GO:0048037 CLOST_1324 79ee626b85602b69384325aac8bdaa61 134 Gene3D G3DSA:3.40.50.720 1 133 5.4E-36 T 13-10-2018 CLOST_1324 79ee626b85602b69384325aac8bdaa61 134 SMART SM00881 10 104 2.5E-15 T 13-10-2018 IPR003781 CoA-binding GO:0048037 CLOST_1324 79ee626b85602b69384325aac8bdaa61 134 SUPERFAMILY SSF51735 2 130 3.41E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0846 cd9d93b3548afc70ddec4bfcca0ec834 457 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 261 366 2.6E-23 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CLOST_0846 cd9d93b3548afc70ddec4bfcca0ec834 457 Gene3D G3DSA:3.20.20.70 6 380 2.8E-112 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0846 cd9d93b3548afc70ddec4bfcca0ec834 457 SUPERFAMILY SSF102114 34 336 9.29E-47 T 13-10-2018 CLOST_0846 cd9d93b3548afc70ddec4bfcca0ec834 457 SMART SM00876 261 368 4.0E-30 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CLOST_0846 cd9d93b3548afc70ddec4bfcca0ec834 457 TIGRFAM TIGR03955 rSAM_HydG: [FeFe] hydrogenase H-cluster radical SAM maturase HydG 2 455 1.9E-191 T 13-10-2018 IPR024007 [FeFe]-hydrogenase maturation HydG, radical SAM CLOST_0846 cd9d93b3548afc70ddec4bfcca0ec834 457 Pfam PF04055 Radical SAM superfamily 79 228 3.6E-7 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0358 65c5b313fd3a581ef280e0f4be27a675 275 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 16 152 1.1E-12 T 13-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CLOST_0358 65c5b313fd3a581ef280e0f4be27a675 275 SUPERFAMILY SSF51621 8 158 3.11E-22 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 CLOST_0358 65c5b313fd3a581ef280e0f4be27a675 275 Gene3D G3DSA:3.20.20.60 2 106 3.0E-13 T 13-10-2018 CLOST_0358 65c5b313fd3a581ef280e0f4be27a675 275 Gene3D G3DSA:3.20.20.60 107 167 6.3E-8 T 13-10-2018 CLOST_0698 ba336e206195ff8c7b717d44ce0baac3 205 SUPERFAMILY SSF53335 3 179 1.78E-30 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0698 ba336e206195ff8c7b717d44ce0baac3 205 Pfam PF13847 Methyltransferase domain 40 139 4.1E-14 T 13-10-2018 IPR025714 Methyltransferase domain CLOST_0698 ba336e206195ff8c7b717d44ce0baac3 205 Gene3D G3DSA:3.40.50.150 2 189 2.2E-26 T 13-10-2018 CLOST_1109 9a59f75535ee9d5177bea9bfa2a2ab4a 105 Gene3D G3DSA:3.40.30.10 1 105 6.1E-26 T 13-10-2018 CLOST_1109 9a59f75535ee9d5177bea9bfa2a2ab4a 105 SUPERFAMILY SSF52833 2 101 1.3E-25 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_1109 9a59f75535ee9d5177bea9bfa2a2ab4a 105 PIRSF PIRSF000077 1 105 1.4E-23 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CLOST_1109 9a59f75535ee9d5177bea9bfa2a2ab4a 105 Pfam PF00085 Thioredoxin 3 102 5.5E-23 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 CLOST_1109 9a59f75535ee9d5177bea9bfa2a2ab4a 105 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CLOST_1884 8cf52db9c904481476be2b9d3126ba2c 196 SMART SM01207 8 184 3.4E-72 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CLOST_1884 8cf52db9c904481476be2b9d3126ba2c 196 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 193 1.9E-50 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CLOST_1884 8cf52db9c904481476be2b9d3126ba2c 196 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 183 6.9E-51 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CLOST_1884 8cf52db9c904481476be2b9d3126ba2c 196 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 192 19.38 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CLOST_0676 b41f5780b40421441a4e52494c13e38e 90 Pfam PF00936 BMC domain 3 78 2.1E-27 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0676 b41f5780b40421441a4e52494c13e38e 90 SMART SM00877 2 78 2.7E-34 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0676 b41f5780b40421441a4e52494c13e38e 90 Gene3D G3DSA:3.30.70.1710 1 90 9.3E-35 T 13-10-2018 CLOST_0676 b41f5780b40421441a4e52494c13e38e 90 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 20 39 - T 13-10-2018 IPR020808 Bacterial microcompartments protein, conserved site CLOST_0676 b41f5780b40421441a4e52494c13e38e 90 SUPERFAMILY SSF143414 1 87 1.2E-28 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0676 b41f5780b40421441a4e52494c13e38e 90 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 36 2.0E-8 T 13-10-2018 CLOST_0702 9406e3bbbcc50e1c588df18437c57b46 251 Gene3D G3DSA:3.40.50.150 51 251 3.1E-22 T 13-10-2018 CLOST_0702 9406e3bbbcc50e1c588df18437c57b46 251 SUPERFAMILY SSF53335 53 227 6.85E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0702 9406e3bbbcc50e1c588df18437c57b46 251 Pfam PF08241 Methyltransferase domain 65 159 1.7E-17 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Gene3D G3DSA:3.30.470.20 662 932 2.6E-99 T 13-10-2018 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Gene3D G3DSA:3.30.470.20 120 401 8.2E-120 T 13-10-2018 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Gene3D G3DSA:3.40.50.20 550 658 1.0E-45 T 13-10-2018 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 SUPERFAMILY SSF56059 128 399 2.83E-103 T 13-10-2018 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 SMART SM01096 420 543 8.8E-59 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1058 12.658 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 SUPERFAMILY SSF52440 553 671 2.59E-45 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 SUPERFAMILY SSF52335 960 1065 1.57E-20 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.0E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.0E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 2.0E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 2.0E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.0E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.0E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.0E-63 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Pfam PF02142 MGS-like domain 963 1037 8.9E-14 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 833 840 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Gene3D G3DSA:3.40.50.1380 951 1066 8.2E-22 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 543 1.2E-36 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 4 1045 0.0 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 SMART SM00851 961 1037 1.3E-12 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Gene3D G3DSA:3.40.50.20 1 116 3.8E-48 T 13-10-2018 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 SUPERFAMILY SSF56059 669 930 1.73E-94 T 13-10-2018 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 SUPERFAMILY SSF52440 1 127 6.91E-49 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 SUPERFAMILY SSF48108 395 548 1.96E-44 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Gene3D G3DSA:1.10.1030.10 403 549 7.2E-42 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 6.7E-79 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_2429 eb03eebfdff3464b9d0a4a39c76c3f1e 1067 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 868 3.4E-33 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_1554 5c51f5d80a038042667ed2d37269dd6f 139 SUPERFAMILY SSF47413 1 48 8.45E-6 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_1554 5c51f5d80a038042667ed2d37269dd6f 139 Gene3D G3DSA:1.10.260.40 1 72 2.5E-5 T 13-10-2018 CLOST_0070 db90aaf2bb8574705abc20f9d319b6d5 376 Pfam PF01385 Probable transposase 168 290 3.2E-13 T 13-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CLOST_0070 db90aaf2bb8574705abc20f9d319b6d5 376 Pfam PF12323 Helix-turn-helix domain 2 45 1.1E-15 T 13-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain CLOST_0070 db90aaf2bb8574705abc20f9d319b6d5 376 Pfam PF07282 Putative transposase DNA-binding domain 303 372 4.3E-20 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal CLOST_0070 db90aaf2bb8574705abc20f9d319b6d5 376 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 256 330 3.5E-11 T 13-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal CLOST_2124 57246268fe49c1c6a516c96905428f60 90 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 15 67 1.8E-13 T 13-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter CLOST_1905 3fbdd9b17640847ad41f5085f6f71ab9 422 SUPERFAMILY SSF63411 3 226 1.23E-17 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CLOST_1905 3fbdd9b17640847ad41f5085f6f71ab9 422 Pfam PF05193 Peptidase M16 inactive domain 182 354 1.0E-21 T 13-10-2018 IPR007863 Peptidase M16, C-terminal CLOST_1905 3fbdd9b17640847ad41f5085f6f71ab9 422 Gene3D G3DSA:3.30.830.10 3 232 4.7E-56 T 13-10-2018 CLOST_1905 3fbdd9b17640847ad41f5085f6f71ab9 422 Gene3D G3DSA:3.30.830.10 238 422 7.5E-42 T 13-10-2018 CLOST_1905 3fbdd9b17640847ad41f5085f6f71ab9 422 SUPERFAMILY SSF63411 243 411 6.0E-27 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CLOST_2364 52fb229687b5eaea7fba575d00fcd570 417 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 44.733 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_2364 52fb229687b5eaea7fba575d00fcd570 417 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4 414 1.3E-177 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_2364 52fb229687b5eaea7fba575d00fcd570 417 Gene3D G3DSA:3.65.10.10 7 413 2.9E-168 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 CLOST_2364 52fb229687b5eaea7fba575d00fcd570 417 Gene3D G3DSA:3.65.10.10 20 229 2.9E-168 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 CLOST_2364 52fb229687b5eaea7fba575d00fcd570 417 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 3.2E-109 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CLOST_2364 52fb229687b5eaea7fba575d00fcd570 417 SUPERFAMILY SSF55205 3 416 3.6E-139 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CLOST_1160 e113a8e5bf05c25c466d2252d3ce777d 629 Gene3D G3DSA:1.20.1270.30 63 232 1.4E-64 T 13-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 CLOST_1160 e113a8e5bf05c25c466d2252d3ce777d 629 Gene3D G3DSA:3.40.50.2030 233 400 3.1E-69 T 13-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_1160 e113a8e5bf05c25c466d2252d3ce777d 629 Gene3D G3DSA:3.40.50.2030 403 626 1.2E-83 T 13-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_1160 e113a8e5bf05c25c466d2252d3ce777d 629 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 16 629 3.6E-200 T 13-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 CLOST_1160 e113a8e5bf05c25c466d2252d3ce777d 629 Pfam PF03063 Prismane/CO dehydrogenase family 48 609 6.6E-167 T 13-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CLOST_1160 e113a8e5bf05c25c466d2252d3ce777d 629 SUPERFAMILY SSF56821 16 629 5.89E-179 T 13-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 CLOST_1160 e113a8e5bf05c25c466d2252d3ce777d 629 PIRSF PIRSF005023 1 629 1.0E-222 T 13-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 CLOST_0454 8abe0d9ea607a3d067ec002191c6c72c 291 Pfam PF07833 Copper amine oxidase N-terminal domain 51 141 1.1E-26 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0454 8abe0d9ea607a3d067ec002191c6c72c 291 SUPERFAMILY SSF55383 53 135 1.5E-24 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0454 8abe0d9ea607a3d067ec002191c6c72c 291 Gene3D G3DSA:3.30.457.10 54 132 1.2E-24 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0145 5eda66c64c09e5eedaeb1469bbdfff0b 211 Gene3D G3DSA:3.40.109.40 3 184 7.0E-32 T 13-10-2018 CLOST_0145 5eda66c64c09e5eedaeb1469bbdfff0b 211 SUPERFAMILY SSF56507 20 179 2.49E-20 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1877 79c519f3283bd309787a0bc230f22961 150 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 2 35 8.4E-15 T 13-10-2018 IPR019933 DivIVA domain CLOST_1877 79c519f3283bd309787a0bc230f22961 150 Pfam PF05103 DivIVA protein 2 132 8.8E-47 T 13-10-2018 IPR007793 DivIVA family CLOST_0658 75548c2269e826c74fbdce7af9285207 479 SUPERFAMILY SSF53850 40 384 1.15E-27 T 13-10-2018 CLOST_0658 75548c2269e826c74fbdce7af9285207 479 Pfam PF13416 Bacterial extracellular solute-binding protein 58 374 8.6E-27 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein CLOST_0658 75548c2269e826c74fbdce7af9285207 479 Gene3D G3DSA:3.40.190.10 37 457 2.8E-37 T 13-10-2018 CLOST_1165 f5d41a5447854d136ef0440e50a5f842 302 Gene3D G3DSA:3.20.20.220 4 302 7.4E-52 T 13-10-2018 CLOST_1165 f5d41a5447854d136ef0440e50a5f842 302 Pfam PF02219 Methylenetetrahydrofolate reductase 4 301 8.4E-37 T 13-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CLOST_1165 f5d41a5447854d136ef0440e50a5f842 302 SUPERFAMILY SSF51730 3 301 1.26E-63 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like CLOST_1515 d17a7730701572a6b3c4dc5ec9fa2a41 341 Gene3D G3DSA:2.30.300.10 23 335 8.7E-29 T 13-10-2018 CLOST_1515 d17a7730701572a6b3c4dc5ec9fa2a41 341 Gene3D G3DSA:3.30.1920.10 217 280 8.7E-29 T 13-10-2018 IPR023399 Baseplate-like, two-layer sandwich fold CLOST_1515 d17a7730701572a6b3c4dc5ec9fa2a41 341 SUPERFAMILY SSF69279 21 184 2.42E-22 T 13-10-2018 CLOST_1515 d17a7730701572a6b3c4dc5ec9fa2a41 341 Gene3D G3DSA:3.55.50.10 105 187 8.7E-29 T 13-10-2018 CLOST_0433 3abd8d0f5219e1f4cc4c2d6ca99efe90 237 Gene3D G3DSA:2.50.20.10 48 234 1.1E-9 T 13-10-2018 CLOST_0433 3abd8d0f5219e1f4cc4c2d6ca99efe90 237 SUPERFAMILY SSF89392 73 231 3.69E-5 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CLOST_0433 3abd8d0f5219e1f4cc4c2d6ca99efe90 237 Pfam PF09865 Predicted periplasmic protein (DUF2092) 79 201 1.1E-4 T 13-10-2018 IPR019207 Protein of unknown function DUF2092, periplasmic CLOST_2546 e930d250182d9af9cf45f8f3dc92da17 312 Gene3D G3DSA:1.10.10.2830 147 269 6.3E-9 T 13-10-2018 CLOST_2546 e930d250182d9af9cf45f8f3dc92da17 312 SUPERFAMILY SSF109709 192 264 2.22E-11 T 13-10-2018 CLOST_2546 e930d250182d9af9cf45f8f3dc92da17 312 Gene3D G3DSA:3.90.1530.30 77 128 1.1E-8 T 13-10-2018 CLOST_2546 e930d250182d9af9cf45f8f3dc92da17 312 Pfam PF02195 ParB-like nuclease domain 60 140 8.6E-8 T 13-10-2018 IPR003115 ParB/Sulfiredoxin CLOST_2546 e930d250182d9af9cf45f8f3dc92da17 312 SUPERFAMILY SSF110849 59 160 2.44E-11 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 Gene3D G3DSA:3.10.580.10 258 367 1.8E-14 T 13-10-2018 CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 Pfam PF00571 CBS domain 319 363 2.5E-5 T 13-10-2018 IPR000644 CBS domain CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 SMART SM00382 28 215 4.9E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 SUPERFAMILY SSF54631 251 370 1.26E-15 T 13-10-2018 CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 16 366 2.9E-106 T 13-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 SUPERFAMILY SSF52540 1 241 1.23E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 Pfam PF00005 ABC transporter 19 165 5.0E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0038 e69e080e601ed2e0f760a027728ac397 374 Gene3D G3DSA:3.40.50.300 1 257 1.9E-74 T 13-10-2018 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 SUPERFAMILY SSF89000 384 434 1.61E-10 T 13-10-2018 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 3 552 52.497 T 13-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 4 551 4.9E-222 T 13-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 Gene3D G3DSA:3.20.20.70 6 372 9.0E-150 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 Gene3D G3DSA:3.30.160.270 373 550 9.0E-48 T 13-10-2018 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 238 251 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 35 51 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 Pfam PF08502 LeuA allosteric (dimerisation) domain 418 550 3.0E-24 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 SMART SM00917 418 551 1.3E-19 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 SUPERFAMILY SSF110921 446 550 1.57E-24 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 SUPERFAMILY SSF51569 17 325 1.54E-97 T 13-10-2018 CLOST_0414 ed7eb83d46851632d964d2d0ac98dbdb 567 Pfam PF00682 HMGL-like 28 304 3.3E-72 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CLOST_2301 7432c435a2ecad95a5bb06590de8d95c 230 SUPERFAMILY SSF53067 2 103 4.75E-28 T 13-10-2018 CLOST_2301 7432c435a2ecad95a5bb06590de8d95c 230 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 211 4.3E-50 T 13-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CLOST_2301 7432c435a2ecad95a5bb06590de8d95c 230 Pfam PF00814 Glycoprotease family 34 148 8.7E-26 T 13-10-2018 IPR000905 Gcp-like domain CLOST_2301 7432c435a2ecad95a5bb06590de8d95c 230 SUPERFAMILY SSF53067 109 205 1.17E-7 T 13-10-2018 CLOST_2301 7432c435a2ecad95a5bb06590de8d95c 230 Gene3D G3DSA:3.30.420.40 3 213 3.3E-53 T 13-10-2018 CLOST_2301 7432c435a2ecad95a5bb06590de8d95c 230 Gene3D G3DSA:3.30.420.40 95 183 3.3E-53 T 13-10-2018 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Gene3D G3DSA:1.10.510.10 103 292 1.9E-53 T 13-10-2018 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 28 51 - T 13-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Gene3D G3DSA:3.30.10.20 382 452 1.0E-14 T 13-10-2018 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Gene3D G3DSA:3.30.10.20 525 586 3.0E-11 T 13-10-2018 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Gene3D G3DSA:3.30.10.20 454 521 1.6E-14 T 13-10-2018 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Pfam PF03793 PASTA domain 527 585 2.4E-9 T 13-10-2018 IPR005543 PASTA domain CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Pfam PF03793 PASTA domain 457 517 8.6E-12 T 13-10-2018 IPR005543 PASTA domain CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Pfam PF03793 PASTA domain 391 451 2.2E-12 T 13-10-2018 IPR005543 PASTA domain CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Pfam PF00069 Protein kinase domain 22 272 5.7E-60 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 Gene3D G3DSA:3.30.200.20 10 101 1.8E-31 T 13-10-2018 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 SMART SM00740 453 518 4.0E-11 T 13-10-2018 IPR005543 PASTA domain CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 SMART SM00740 521 586 4.0E-9 T 13-10-2018 IPR005543 PASTA domain CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 SMART SM00740 384 451 1.6E-14 T 13-10-2018 IPR005543 PASTA domain CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 SMART SM00220 22 279 7.9E-76 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 SUPERFAMILY SSF56112 15 276 6.47E-84 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily CLOST_1849 d9d5defbdc5e0f9468911f4ef2b9e6fb 667 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 13-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 Gene3D G3DSA:3.40.50.150 157 438 2.1E-76 T 13-10-2018 CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 SUPERFAMILY SSF48013 12 138 2.88E-26 T 13-10-2018 IPR035926 NusB-like superfamily CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 267 277 1.2E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 334 346 1.2E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 383 399 1.2E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 421 438 1.2E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 238 252 1.2E-27 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 SUPERFAMILY SSF53335 150 438 1.04E-65 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 Pfam PF01029 NusB family 14 135 5.9E-26 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 16 438 4.4E-99 T 13-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 Pfam PF01189 16S rRNA methyltransferase RsmB/F 256 437 6.6E-47 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 CLOST_1852 db9fe397c1f78001c8bfa1457047b5be 444 Gene3D G3DSA:1.10.940.10 11 153 3.1E-29 T 13-10-2018 IPR035926 NusB-like superfamily CLOST_1924 825c6273b835353d44714292caf6dd7b 213 TIGRFAM TIGR01076 sortase_fam: sortase 79 204 5.6E-27 T 13-10-2018 IPR005754 Sortase family CLOST_1924 825c6273b835353d44714292caf6dd7b 213 Gene3D G3DSA:2.40.260.10 24 211 2.2E-47 T 13-10-2018 IPR023365 Sortase domain superfamily CLOST_1924 825c6273b835353d44714292caf6dd7b 213 Pfam PF04203 Sortase family 81 203 1.0E-29 T 13-10-2018 IPR005754 Sortase family CLOST_1924 825c6273b835353d44714292caf6dd7b 213 SUPERFAMILY SSF63817 71 205 7.06E-37 T 13-10-2018 IPR023365 Sortase domain superfamily CLOST_1325 fa848d80097c0744ae23664e6b44cd3a 215 SUPERFAMILY SSF54211 4 125 6.83E-40 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_1325 fa848d80097c0744ae23664e6b44cd3a 215 SUPERFAMILY SSF54980 136 201 4.6E-8 T 13-10-2018 IPR035647 EF-G domain III/V-like CLOST_1325 fa848d80097c0744ae23664e6b44cd3a 215 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 200 7.9E-56 T 13-10-2018 IPR015796 Impact family, bacterial/archaeal CLOST_1325 fa848d80097c0744ae23664e6b44cd3a 215 Pfam PF01205 Uncharacterized protein family UPF0029 19 123 1.9E-32 T 13-10-2018 IPR001498 Impact, N-terminal CLOST_1325 fa848d80097c0744ae23664e6b44cd3a 215 Gene3D G3DSA:3.30.230.30 1 132 7.1E-49 T 13-10-2018 IPR036956 Impact, N-terminal domain superfamily CLOST_1325 fa848d80097c0744ae23664e6b44cd3a 215 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 13-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CLOST_1325 fa848d80097c0744ae23664e6b44cd3a 215 Pfam PF09186 Domain of unknown function (DUF1949) 141 194 5.9E-9 T 13-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 489 32.45 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 Gene3D G3DSA:1.10.10.350 395 494 1.9E-24 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 SUPERFAMILY SSF48163 321 488 5.1E-35 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 9.9E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 9.9E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 200 210 9.9E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 9.9E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 PRINTS PR00987 Glutamyl-tRNA synthetase signature 216 224 9.9E-26 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 327 4.1E-111 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 487 5.2E-175 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 Gene3D G3DSA:3.40.50.620 1 336 1.8E-150 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_2245 6c1b49d7b43be7c77054533b9e00554d 495 SUPERFAMILY SSF52374 3 317 1.93E-112 T 13-10-2018 CLOST_2073 8150ebfb0875b1f47e99ad25bf792c47 373 Pfam PF01594 AI-2E family transporter 14 350 1.0E-50 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like CLOST_2073 8150ebfb0875b1f47e99ad25bf792c47 373 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 14 345 1.2E-74 T 13-10-2018 IPR014227 Putative transport protein YtvI-like CLOST_0881 9915d5bd4188aa5b2ced0f33e9e3fead 198 Pfam PF00005 ABC transporter 20 151 9.9E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0881 9915d5bd4188aa5b2ced0f33e9e3fead 198 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0881 9915d5bd4188aa5b2ced0f33e9e3fead 198 SUPERFAMILY SSF52540 3 194 5.33E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0881 9915d5bd4188aa5b2ced0f33e9e3fead 198 SMART SM00382 28 190 2.7E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0881 9915d5bd4188aa5b2ced0f33e9e3fead 198 Gene3D G3DSA:3.40.50.300 2 195 1.9E-44 T 13-10-2018 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 Hamap MF_00551 Uridine kinase [udk]. 1 206 41.623 T 13-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 Gene3D G3DSA:3.40.50.300 2 210 2.8E-65 T 13-10-2018 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 TIGRFAM TIGR00235 udk: uridine kinase 5 205 4.6E-88 T 13-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 PRINTS PR00988 Uridine kinase signature 34 45 1.2E-36 T 13-10-2018 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 PRINTS PR00988 Uridine kinase signature 150 161 1.2E-36 T 13-10-2018 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 PRINTS PR00988 Uridine kinase signature 4 21 1.2E-36 T 13-10-2018 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 PRINTS PR00988 Uridine kinase signature 136 146 1.2E-36 T 13-10-2018 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 PRINTS PR00988 Uridine kinase signature 79 94 1.2E-36 T 13-10-2018 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 PRINTS PR00988 Uridine kinase signature 172 185 1.2E-36 T 13-10-2018 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 6 192 1.5E-44 T 13-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 CLOST_1608 77753d25badbceee36fe0d13741d10dc 210 SUPERFAMILY SSF52540 3 197 2.03E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 SUPERFAMILY SSF52540 176 442 1.1E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 SMART SM00487 258 449 1.3E-33 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 Pfam PF17191 RecG wedge domain 9 164 1.4E-29 T 13-10-2018 IPR033454 RecG, wedge domain CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 Gene3D G3DSA:3.40.50.300 224 440 2.9E-85 T 13-10-2018 CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 SUPERFAMILY SSF50249 4 170 1.29E-35 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 SMART SM00490 494 579 3.3E-22 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 Pfam PF00270 DEAD/DEAH box helicase 263 423 1.1E-21 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 Pfam PF00271 Helicase conserved C-terminal domain 467 578 1.1E-20 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 SUPERFAMILY SSF52540 373 634 5.09E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 653 4.6E-224 T 13-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 Gene3D G3DSA:3.40.50.300 447 619 1.5E-60 T 13-10-2018 CLOST_1841 1158bcdf08b6544901047a7f22e09c4f 685 Gene3D G3DSA:2.40.50.140 45 140 9.8E-20 T 13-10-2018 CLOST_1895 5674e095dc68d1e3ef4b97fa8802fee4 364 SUPERFAMILY SSF53756 1 361 4.4E-101 T 13-10-2018 CLOST_1895 5674e095dc68d1e3ef4b97fa8802fee4 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 359 3.4E-89 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1895 5674e095dc68d1e3ef4b97fa8802fee4 364 Gene3D G3DSA:3.40.50.2000 165 347 2.4E-103 T 13-10-2018 CLOST_1895 5674e095dc68d1e3ef4b97fa8802fee4 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 363 31.28 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1895 5674e095dc68d1e3ef4b97fa8802fee4 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 193 345 2.1E-35 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 CLOST_1895 5674e095dc68d1e3ef4b97fa8802fee4 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 1.7E-40 T 13-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1895 5674e095dc68d1e3ef4b97fa8802fee4 364 Gene3D G3DSA:3.40.50.2000 4 352 2.4E-103 T 13-10-2018 CLOST_0765 8f6181444c6bc1d2bd1ea51901570750 178 Pfam PF03773 Predicted permease 33 173 8.4E-14 T 13-10-2018 IPR005524 Predicted permease DUF318 CLOST_0930 dcd09d35f8cb306f5d74a74ed5e3c1a3 87 PIRSF PIRSF037257 1 86 3.1E-30 T 13-10-2018 IPR009366 Protein Veg GO:0006355 CLOST_0930 dcd09d35f8cb306f5d74a74ed5e3c1a3 87 Pfam PF06257 Biofilm formation stimulator VEG 6 77 8.3E-30 T 13-10-2018 IPR009366 Protein Veg GO:0006355 CLOST_0930 dcd09d35f8cb306f5d74a74ed5e3c1a3 87 Gene3D G3DSA:2.30.30.100 1 79 3.8E-24 T 13-10-2018 CLOST_1016 e803f2055883cf9dffcdde7827d3eb4a 284 SUPERFAMILY SSF55729 3 139 2.66E-17 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1016 e803f2055883cf9dffcdde7827d3eb4a 284 Gene3D G3DSA:3.40.630.30 2 203 1.5E-24 T 13-10-2018 CLOST_1016 e803f2055883cf9dffcdde7827d3eb4a 284 Pfam PF00583 Acetyltransferase (GNAT) family 27 130 8.3E-10 T 13-10-2018 IPR000182 GNAT domain CLOST_2100 5d2f3f17f99e8d9d8a262f0096e41e28 392 SUPERFAMILY SSF54862 78 246 1.12E-10 T 13-10-2018 CLOST_2100 5d2f3f17f99e8d9d8a262f0096e41e28 392 Gene3D G3DSA:3.90.1010.20 327 392 3.4E-5 T 13-10-2018 CLOST_2100 5d2f3f17f99e8d9d8a262f0096e41e28 392 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 212 223 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2100 5d2f3f17f99e8d9d8a262f0096e41e28 392 Pfam PF12801 4Fe-4S binding domain 168 208 1.2E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2100 5d2f3f17f99e8d9d8a262f0096e41e28 392 Pfam PF12801 4Fe-4S binding domain 70 110 2.6E-11 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2100 5d2f3f17f99e8d9d8a262f0096e41e28 392 Pfam PF04205 FMN-binding domain 314 385 2.0E-17 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOST_2100 5d2f3f17f99e8d9d8a262f0096e41e28 392 SMART SM00900 314 388 7.2E-20 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 SUPERFAMILY SSF53732 36 509 3.27E-107 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 Pfam PF00694 Aconitase C-terminal domain 660 705 8.2E-5 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 SUPERFAMILY SSF52016 522 772 5.1E-30 T 13-10-2018 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 Gene3D G3DSA:3.30.499.10 350 498 2.0E-30 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 Pfam PF00330 Aconitase family (aconitate hydratase) 55 485 2.6E-79 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 Gene3D G3DSA:3.40.1060.10 199 311 3.9E-20 T 13-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 PRINTS PR00415 Aconitase family signature 154 167 1.4E-6 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 PRINTS PR00415 Aconitase family signature 230 243 1.4E-6 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 PRINTS PR00415 Aconitase family signature 428 441 1.4E-6 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 PRINTS PR00415 Aconitase family signature 311 325 1.4E-6 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 PRINTS PR00415 Aconitase family signature 371 382 1.4E-6 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 CLOST_2277 615659c6a082957e17d2c78d7b926ba4 773 Gene3D G3DSA:3.30.499.10 25 198 1.3E-22 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 CLOST_1031 ea2c177b2f1b9c442f5aab151e8265c7 198 Pfam PF08849 Putative inner membrane protein (DUF1819) 3 185 7.0E-59 T 13-10-2018 IPR014948 Protein of unknown function DUF1819, putative inner membrane CLOST_1031 ea2c177b2f1b9c442f5aab151e8265c7 198 Gene3D G3DSA:1.10.3540.10 1 196 2.1E-51 T 13-10-2018 CLOST_1345 f8aab4d5b8b87abe853714046f82441b 295 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site CLOST_1345 f8aab4d5b8b87abe853714046f82441b 295 Pfam PF00348 Polyprenyl synthetase 30 270 3.3E-59 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 CLOST_1345 f8aab4d5b8b87abe853714046f82441b 295 Gene3D G3DSA:1.10.600.10 1 295 1.3E-93 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily CLOST_1345 f8aab4d5b8b87abe853714046f82441b 295 SUPERFAMILY SSF48576 1 276 5.76E-83 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily CLOST_1345 f8aab4d5b8b87abe853714046f82441b 295 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 213 225 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site CLOST_0168 3473a2f1fb15a160a2d8c527526ea23c 578 Gene3D G3DSA:2.60.120.10 405 570 3.4E-25 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0168 3473a2f1fb15a160a2d8c527526ea23c 578 Gene3D G3DSA:3.90.550.10 25 285 3.4E-9 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0168 3473a2f1fb15a160a2d8c527526ea23c 578 SMART SM00100 436 553 3.1E-8 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_0168 3473a2f1fb15a160a2d8c527526ea23c 578 SUPERFAMILY SSF53448 33 293 3.04E-17 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0168 3473a2f1fb15a160a2d8c527526ea23c 578 Pfam PF00027 Cyclic nucleotide-binding domain 455 540 5.8E-9 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_0168 3473a2f1fb15a160a2d8c527526ea23c 578 SUPERFAMILY SSF51206 422 554 7.58E-25 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like CLOST_1084 886fed0d76f2048fc44547b304598ca9 221 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 5 220 40.502 T 13-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_1084 886fed0d76f2048fc44547b304598ca9 221 SMART SM00986 49 209 3.5E-37 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_1084 886fed0d76f2048fc44547b304598ca9 221 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 13-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_1084 886fed0d76f2048fc44547b304598ca9 221 Pfam PF03167 Uracil DNA glycosylase superfamily 53 208 1.9E-24 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_1084 886fed0d76f2048fc44547b304598ca9 221 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 211 1.6E-84 T 13-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_1084 886fed0d76f2048fc44547b304598ca9 221 SUPERFAMILY SSF52141 2 221 2.07E-92 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_1084 886fed0d76f2048fc44547b304598ca9 221 SMART SM00987 49 209 3.5E-37 T 13-10-2018 CLOST_1084 886fed0d76f2048fc44547b304598ca9 221 Gene3D G3DSA:3.40.470.10 1 221 7.8E-97 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_2169 b3b2721302c796760c3c0c3311e21cc8 113 Gene3D G3DSA:3.90.1030.10 1 113 1.1E-48 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2169 b3b2721302c796760c3c0c3311e21cc8 113 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 2 113 28.769 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2169 b3b2721302c796760c3c0c3311e21cc8 113 Pfam PF01196 Ribosomal protein L17 18 113 9.7E-41 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2169 b3b2721302c796760c3c0c3311e21cc8 113 SUPERFAMILY SSF64263 3 113 3.4E-47 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2169 b3b2721302c796760c3c0c3311e21cc8 113 TIGRFAM TIGR00059 L17: ribosomal protein bL17 4 113 1.9E-48 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_0753 84f0a69871d509096f9ad819fae146cc 178 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 171 3.8E-27 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CLOST_0753 84f0a69871d509096f9ad819fae146cc 178 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 175 1.2E-53 T 13-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 CLOST_0753 84f0a69871d509096f9ad819fae146cc 178 Gene3D G3DSA:3.40.920.10 1 177 1.0E-54 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_0753 84f0a69871d509096f9ad819fae146cc 178 SUPERFAMILY SSF53323 1 174 4.05E-37 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1429 3f0ead1931a1ce5d6755e403d4bcb335 325 Gene3D G3DSA:3.40.190.10 136 320 1.2E-10 T 13-10-2018 CLOST_1429 3f0ead1931a1ce5d6755e403d4bcb335 325 Gene3D G3DSA:3.40.190.10 32 135 8.2E-8 T 13-10-2018 CLOST_1429 3f0ead1931a1ce5d6755e403d4bcb335 325 SUPERFAMILY SSF53850 36 264 1.16E-25 T 13-10-2018 CLOST_1429 3f0ead1931a1ce5d6755e403d4bcb335 325 Pfam PF13379 NMT1-like family 34 222 1.6E-12 T 13-10-2018 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 108 129 5.0E-59 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 5.0E-59 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 5.0E-59 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 32 54 5.0E-59 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 5.0E-59 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 5.0E-59 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 73 100 5.0E-59 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 282 33.062 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 SUPERFAMILY SSF53223 2 120 2.78E-28 T 13-10-2018 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 Gene3D G3DSA:3.40.50.10860 7 275 4.4E-92 T 13-10-2018 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 SUPERFAMILY SSF51735 121 280 2.48E-40 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 281 2.8E-58 T 13-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 Gene3D G3DSA:3.40.50.720 5 258 4.4E-92 T 13-10-2018 CLOST_0535 971b8d2f7a2a0e4051971e31b94dabfa 294 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 119 3.7E-31 T 13-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 CLOST_0330 3c964bfc649ff98ca13e1598f3b31618 190 SUPERFAMILY SSF55729 1 156 1.13E-8 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0330 3c964bfc649ff98ca13e1598f3b31618 190 Gene3D G3DSA:3.40.630.30 1 184 3.2E-7 T 13-10-2018 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 PRINTS PR00124 ATP synthase C subunit signature 12 31 2.4E-20 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 PRINTS PR00124 ATP synthase C subunit signature 33 48 2.4E-20 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 PRINTS PR00124 ATP synthase C subunit signature 50 75 2.4E-20 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 Hamap MF_01396 ATP synthase subunit c [atpH]. 7 75 15.914 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 Gene3D G3DSA:1.20.20.10 2 78 2.3E-32 T 13-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 77 1.8E-20 T 13-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 13-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 Pfam PF00137 ATP synthase subunit C 12 74 3.4E-18 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CLOST_2121 18c7b102e633c2a5a3ca326d9d97b0a0 84 SUPERFAMILY SSF81333 5 79 1.44E-20 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily CLOST_2275 65ee26517de20821472455cb2f0682fc 159 SUPERFAMILY SSF46785 19 153 6.96E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2275 65ee26517de20821472455cb2f0682fc 159 Gene3D G3DSA:3.30.1490.190 102 159 1.0E-9 T 13-10-2018 CLOST_2275 65ee26517de20821472455cb2f0682fc 159 Pfam PF01475 Ferric uptake regulator family 28 122 1.2E-21 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CLOST_2275 65ee26517de20821472455cb2f0682fc 159 Gene3D G3DSA:1.10.10.10 12 95 2.9E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2484 dd5a039ef78c6bd0d71a5cec5038c3d8 509 PIRSF PIRSF005943 1 509 4.2E-124 T 13-10-2018 IPR016471 Nicotinamide phosphoribosyl transferase Reactome: R-HSA-1368108|Reactome: R-HSA-197264 CLOST_2484 dd5a039ef78c6bd0d71a5cec5038c3d8 509 SUPERFAMILY SSF51690 183 504 2.53E-25 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CLOST_2484 dd5a039ef78c6bd0d71a5cec5038c3d8 509 Gene3D G3DSA:3.20.20.70 148 414 1.8E-75 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_2484 dd5a039ef78c6bd0d71a5cec5038c3d8 509 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 184 473 5.9E-28 T 13-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CLOST_0007 a6ef1697af188d2d4673719d0255fe9e 405 SMART SM00052 2 196 0.0016 T 13-10-2018 IPR001633 EAL domain CLOST_0007 a6ef1697af188d2d4673719d0255fe9e 405 Pfam PF00563 EAL domain 81 191 4.4E-11 T 13-10-2018 IPR001633 EAL domain CLOST_0007 a6ef1697af188d2d4673719d0255fe9e 405 Gene3D G3DSA:3.20.20.450 56 193 9.7E-17 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0007 a6ef1697af188d2d4673719d0255fe9e 405 Pfam PF08668 HDOD domain 205 321 6.3E-14 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD CLOST_0007 a6ef1697af188d2d4673719d0255fe9e 405 PIRSF PIRSF003180 1 403 2.1E-118 T 13-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing CLOST_0007 a6ef1697af188d2d4673719d0255fe9e 405 SUPERFAMILY SSF109604 182 383 3.77E-33 T 13-10-2018 CLOST_0007 a6ef1697af188d2d4673719d0255fe9e 405 SUPERFAMILY SSF141868 3 195 7.59E-29 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0007 a6ef1697af188d2d4673719d0255fe9e 405 Gene3D G3DSA:1.10.3210.10 194 352 2.1E-21 T 13-10-2018 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 Pfam PF04552 Sigma-54, DNA binding domain 192 349 1.4E-59 T 13-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 239 258 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 Gene3D G3DSA:1.10.10.1330 1 124 2.9E-20 T 13-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 Pfam PF04963 Sigma-54 factor, core binding domain 1 178 2.5E-49 T 13-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 330 337 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 Gene3D G3DSA:1.10.10.60 292 349 4.0E-25 T 13-10-2018 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 2 349 1.4E-121 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 PRINTS PR00045 Sigma-54 factor signature 251 263 4.2E-28 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 PRINTS PR00045 Sigma-54 factor signature 325 343 4.2E-28 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 PRINTS PR00045 Sigma-54 factor signature 64 81 4.2E-28 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 CLOST_0640 0290898a9f9402ea7dfb16bb84ba4c71 351 PRINTS PR00045 Sigma-54 factor signature 267 278 4.2E-28 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 CLOST_0279 96ade0fb164971d37b24b602af8caac5 433 Pfam PF01548 Transposase 10 161 1.9E-24 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CLOST_0279 96ade0fb164971d37b24b602af8caac5 433 Pfam PF02371 Transposase IS116/IS110/IS902 family 285 364 6.6E-23 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CLOST_1718 37da71f17071dc015e9cff4202af13ea 408 SUPERFAMILY SSF52540 217 405 1.35E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1718 37da71f17071dc015e9cff4202af13ea 408 SMART SM00382 215 360 6.8E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1718 37da71f17071dc015e9cff4202af13ea 408 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 2 302 7.9E-67 T 13-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 CLOST_1718 37da71f17071dc015e9cff4202af13ea 408 SMART SM00962 215 406 4.0E-54 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1718 37da71f17071dc015e9cff4202af13ea 408 Gene3D G3DSA:1.20.120.1380 168 396 2.4E-69 T 13-10-2018 CLOST_1718 37da71f17071dc015e9cff4202af13ea 408 Pfam PF00448 SRP54-type protein, GTPase domain 217 405 8.1E-46 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CLOST_1718 37da71f17071dc015e9cff4202af13ea 408 Gene3D G3DSA:3.40.50.300 210 394 2.4E-69 T 13-10-2018 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.1E-41 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.1E-41 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.1E-41 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.1E-41 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.1E-41 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.1E-41 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 43.876 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 Gene3D G3DSA:1.10.287.610 100 151 2.2E-25 T 13-10-2018 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 13-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 SUPERFAMILY SSF52313 6 231 3.53E-99 T 13-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 2.4E-111 T 13-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1705 62a2a1b51c1a04b98916c09fcc08ee32 248 Pfam PF00318 Ribosomal protein S2 9 224 2.0E-102 T 13-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_0724 cdece76b633f0716059b1c4db95de8f2 302 SUPERFAMILY SSF46600 167 205 9.94E-7 T 13-10-2018 IPR036876 UVR domain superfamily CLOST_0724 cdece76b633f0716059b1c4db95de8f2 302 SMART SM00465 1 76 4.0E-13 T 13-10-2018 IPR000305 GIY-YIG endonuclease CLOST_0724 cdece76b633f0716059b1c4db95de8f2 302 Gene3D G3DSA:3.40.1440.10 1 80 8.6E-24 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 CLOST_0724 cdece76b633f0716059b1c4db95de8f2 302 Pfam PF02151 UvrB/uvrC motif 170 203 1.6E-4 T 13-10-2018 IPR001943 UVR domain GO:0005515 CLOST_0724 cdece76b633f0716059b1c4db95de8f2 302 Pfam PF01541 GIY-YIG catalytic domain 2 71 4.6E-8 T 13-10-2018 IPR000305 GIY-YIG endonuclease CLOST_0724 cdece76b633f0716059b1c4db95de8f2 302 SUPERFAMILY SSF82771 1 76 2.22E-17 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 CLOST_2144 384060b0422c24149c33772009551a26 252 SUPERFAMILY SSF53335 10 213 1.14E-25 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_2144 384060b0422c24149c33772009551a26 252 Pfam PF05175 Methyltransferase small domain 35 172 5.8E-12 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 CLOST_2144 384060b0422c24149c33772009551a26 252 Gene3D G3DSA:3.40.50.150 9 247 1.0E-61 T 13-10-2018 CLOST_1668 a76be433cc2b70004ba6899193ea46d2 241 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 25 238 28.517 T 13-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CLOST_1668 a76be433cc2b70004ba6899193ea46d2 241 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 26 231 2.1E-53 T 13-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 CLOST_1668 a76be433cc2b70004ba6899193ea46d2 241 Gene3D G3DSA:1.10.1760.20 25 233 8.8E-54 T 13-10-2018 CLOST_1668 a76be433cc2b70004ba6899193ea46d2 241 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 25 230 4.9E-89 T 13-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CLOST_1937 5c84bcafef144459bd54d4c84767192b 301 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1937 5c84bcafef144459bd54d4c84767192b 301 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 297 2.9E-71 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1937 5c84bcafef144459bd54d4c84767192b 301 SUPERFAMILY SSF55120 75 298 1.92E-65 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1937 5c84bcafef144459bd54d4c84767192b 301 Gene3D G3DSA:3.30.2350.10 84 300 1.8E-65 T 13-10-2018 CLOST_1937 5c84bcafef144459bd54d4c84767192b 301 Pfam PF00849 RNA pseudouridylate synthase 91 241 5.7E-31 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_1125 e5a1de9f1f119feaa2603f1366ef6340 392 Gene3D G3DSA:3.60.40.10 1 229 4.0E-30 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1125 e5a1de9f1f119feaa2603f1366ef6340 392 SUPERFAMILY SSF81606 7 219 4.45E-9 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1125 e5a1de9f1f119feaa2603f1366ef6340 392 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 32 219 1.5E-16 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_1893 df88316de88e5148ce27c2999dcdd92b 235 Gene3D G3DSA:3.30.70.1880 86 235 1.2E-35 T 13-10-2018 CLOST_1893 df88316de88e5148ce27c2999dcdd92b 235 Pfam PF05949 Bacterial protein of unknown function (DUF881) 87 229 1.7E-32 T 13-10-2018 IPR010273 Protein of unknown function DUF881 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 9 676 1.0E-273 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 Gene3D G3DSA:3.30.870.10 320 500 2.4E-76 T 13-10-2018 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 Pfam PF02503 Polyphosphate kinase middle domain 123 320 2.2E-70 T 13-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 Gene3D G3DSA:3.30.870.10 503 683 1.1E-67 T 13-10-2018 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 Gene3D G3DSA:3.30.1840.10 2 311 7.3E-109 T 13-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 PIRSF PIRSF015589 1 693 7.9E-282 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 Pfam PF13090 Polyphosphate kinase C-terminal domain 329 675 8.2E-156 T 13-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 Hamap MF_00347 Polyphosphate kinase [ppk]. 6 680 28.746 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 SUPERFAMILY SSF56024 320 492 3.45E-59 T 13-10-2018 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 SUPERFAMILY SSF140356 8 110 2.22E-37 T 13-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 Pfam PF13089 Polyphosphate kinase N-terminal domain 9 114 1.4E-39 T 13-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 SUPERFAMILY SSF143724 112 313 1.96E-64 T 13-10-2018 CLOST_0906 9acdd1c111252a7ced5e224d652be6c9 701 SUPERFAMILY SSF56024 499 683 1.86E-68 T 13-10-2018 CLOST_2538 5e1d77217ae9530badaf0d9dc822583a 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 5.7E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_2538 5e1d77217ae9530badaf0d9dc822583a 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 5.7E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_2538 5e1d77217ae9530badaf0d9dc822583a 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 5.7E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_2538 5e1d77217ae9530badaf0d9dc822583a 149 Gene3D G3DSA:1.10.10.10 2 146 4.8E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2538 5e1d77217ae9530badaf0d9dc822583a 149 SMART SM00347 28 129 1.3E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_2538 5e1d77217ae9530badaf0d9dc822583a 149 Pfam PF12802 MarR family 34 93 1.5E-10 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_2538 5e1d77217ae9530badaf0d9dc822583a 149 SUPERFAMILY SSF46785 15 144 1.85E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2568 7a1785020a5f2a338b0905ce7e2441e7 211 Pfam PF03358 NADPH-dependent FMN reductase 1 156 3.1E-32 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CLOST_2568 7a1785020a5f2a338b0905ce7e2441e7 211 SUPERFAMILY SSF52218 1 189 1.86E-45 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_2568 7a1785020a5f2a338b0905ce7e2441e7 211 Gene3D G3DSA:3.40.50.360 1 209 5.1E-40 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 SMART SM00422 5 69 0.0018 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 Pfam PF00239 Resolvase, N terminal domain 62 192 2.6E-18 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 Gene3D G3DSA:1.10.1660.10 2 61 5.8E-16 T 13-10-2018 CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 SUPERFAMILY SSF53041 60 193 1.7E-21 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 SUPERFAMILY SSF46955 3 59 3.11E-15 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 Pfam PF13411 MerR HTH family regulatory protein 5 59 6.6E-14 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 ProSitePatterns PS00397 Site-specific recombinases active site. 65 73 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 SMART SM00857 62 203 1.8E-15 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOST_0635 d7be877a4b54d9242bf40027f80580cc 218 Gene3D G3DSA:3.40.50.1390 62 159 1.4E-23 T 13-10-2018 CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 Pfam PF03023 MviN-like protein 27 469 9.6E-84 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 1 459 16.813 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 PIRSF PIRSF002869 1 500 6.7E-120 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 3 494 1.8E-107 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 PRINTS PR01806 Virulence factor MviN signature 128 152 4.0E-25 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 PRINTS PR01806 Virulence factor MviN signature 31 50 4.0E-25 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 PRINTS PR01806 Virulence factor MviN signature 152 173 4.0E-25 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 PRINTS PR01806 Virulence factor MviN signature 401 418 4.0E-25 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 PRINTS PR01806 Virulence factor MviN signature 349 368 4.0E-25 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_0370 f883a62e4c3f67520c1e3da1a61acafc 505 PRINTS PR01806 Virulence factor MviN signature 251 277 4.0E-25 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CLOST_2466 fd440bba84699f4b723356734007e3b3 168 SUPERFAMILY SSF50475 5 166 4.78E-21 T 13-10-2018 CLOST_2466 fd440bba84699f4b723356734007e3b3 168 Gene3D G3DSA:2.30.110.10 2 168 8.6E-23 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 CLOST_2466 fd440bba84699f4b723356734007e3b3 168 Pfam PF01613 Flavin reductase like domain 19 165 1.1E-4 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 CLOST_2492 e7fe98e46be74ebe5a4904309af1cdfe 432 SUPERFAMILY SSF53474 10 230 6.0E-20 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold CLOST_2492 e7fe98e46be74ebe5a4904309af1cdfe 432 SUPERFAMILY SSF55729 295 404 3.55E-20 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2492 e7fe98e46be74ebe5a4904309af1cdfe 432 Gene3D G3DSA:3.40.50.1820 6 229 1.4E-19 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold CLOST_2492 e7fe98e46be74ebe5a4904309af1cdfe 432 Pfam PF00583 Acetyltransferase (GNAT) family 306 389 2.1E-13 T 13-10-2018 IPR000182 GNAT domain CLOST_2492 e7fe98e46be74ebe5a4904309af1cdfe 432 Gene3D G3DSA:3.40.630.30 253 420 2.0E-21 T 13-10-2018 CLOST_1670 3e92689966e34a04f334aad89fe77bb9 179 Gene3D G3DSA:3.30.70.120 88 158 4.2E-5 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CLOST_1670 3e92689966e34a04f334aad89fe77bb9 179 Hamap MF_01515 UPF0316 protein . 5 173 26.467 T 13-10-2018 IPR022930 Protein of unknown function UPF0316 CLOST_1670 3e92689966e34a04f334aad89fe77bb9 179 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 113 164 3.4E-10 T 13-10-2018 IPR019264 Domain of unknown function DUF2179 CLOST_0061 2b66534bfaf88a80f26f4fa40d1acca5 201 Pfam PF08241 Methyltransferase domain 48 140 2.1E-19 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CLOST_0061 2b66534bfaf88a80f26f4fa40d1acca5 201 SUPERFAMILY SSF53335 11 191 1.67E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0061 2b66534bfaf88a80f26f4fa40d1acca5 201 Gene3D G3DSA:3.40.50.150 1 195 4.5E-36 T 13-10-2018 CLOST_0108 1d9a2c1c3e18616739551cf40a76ac06 552 SUPERFAMILY SSF52540 36 226 3.94E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0108 1d9a2c1c3e18616739551cf40a76ac06 552 Gene3D G3DSA:1.10.8.60 11 234 6.5E-98 T 13-10-2018 CLOST_0108 1d9a2c1c3e18616739551cf40a76ac06 552 SUPERFAMILY SSF48019 241 358 3.32E-12 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CLOST_0108 1d9a2c1c3e18616739551cf40a76ac06 552 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 7 353 4.6E-130 T 13-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CLOST_0108 1d9a2c1c3e18616739551cf40a76ac06 552 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 231 363 1.2E-9 T 13-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CLOST_0108 1d9a2c1c3e18616739551cf40a76ac06 552 Pfam PF13177 DNA polymerase III, delta subunit 23 177 1.9E-42 T 13-10-2018 CLOST_0108 1d9a2c1c3e18616739551cf40a76ac06 552 Gene3D G3DSA:3.40.50.300 16 176 6.5E-98 T 13-10-2018 CLOST_0108 1d9a2c1c3e18616739551cf40a76ac06 552 SMART SM00382 40 178 1.9E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1413 1569 1.4E-48 T 13-10-2018 IPR000160 GGDEF domain CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 Pfam PF00069 Protein kinase domain 42 228 1.4E-6 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 SUPERFAMILY SSF52540 298 504 4.65E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 Gene3D G3DSA:1.25.40.10 652 804 1.7E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 Gene3D G3DSA:3.30.70.270 1408 1576 3.8E-49 T 13-10-2018 CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 SUPERFAMILY SSF55073 1417 1573 7.22E-45 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 Gene3D G3DSA:1.10.510.10 22 248 2.5E-12 T 13-10-2018 CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 SUPERFAMILY SSF48452 768 981 3.09E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 SUPERFAMILY SSF55781 1601 1748 2.89E-5 T 13-10-2018 CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 SUPERFAMILY SSF48452 648 812 1.17E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1414 1567 5.3E-43 T 13-10-2018 IPR000160 GGDEF domain CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 Gene3D G3DSA:1.25.40.10 805 988 2.5E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 SUPERFAMILY SSF56112 6 246 2.86E-15 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 Gene3D G3DSA:3.30.450.40 1594 1748 6.8E-6 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_0574 cddb7d5b4fbb08d4a1d9bd103ec91e70 1751 SMART SM00267 1401 1571 9.6E-49 T 13-10-2018 IPR000160 GGDEF domain CLOST_0943 42c1c5dde8873afd6f654f607030de29 134 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 26 96 1.8E-14 T 13-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 CLOST_0943 42c1c5dde8873afd6f654f607030de29 134 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 23 96 1.8E-10 T 13-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 CLOST_1373 888a02ab1fccf398ff981d97150ce399 109 SUPERFAMILY SSF118010 1 107 1.7E-29 T 13-10-2018 IPR036764 Cysteine protease Prp superfamily CLOST_1373 888a02ab1fccf398ff981d97150ce399 109 Pfam PF04327 Cysteine protease Prp 1 102 4.5E-25 T 13-10-2018 IPR007422 Cysteine protease Prp CLOST_1373 888a02ab1fccf398ff981d97150ce399 109 Gene3D G3DSA:3.30.70.1490 1 108 8.6E-29 T 13-10-2018 IPR036764 Cysteine protease Prp superfamily CLOST_0322 69d130f2f2a3726a654ffc7a98952298 160 SUPERFAMILY SSF55729 38 156 1.54E-25 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0322 69d130f2f2a3726a654ffc7a98952298 160 Pfam PF00583 Acetyltransferase (GNAT) family 39 139 2.1E-15 T 13-10-2018 IPR000182 GNAT domain CLOST_0322 69d130f2f2a3726a654ffc7a98952298 160 Gene3D G3DSA:3.40.630.30 10 159 1.5E-30 T 13-10-2018 CLOST_0022 e853fc4ab14b46b71332089e129b686a 209 Gene3D G3DSA:1.10.357.10 1 209 9.6E-49 T 13-10-2018 CLOST_0022 e853fc4ab14b46b71332089e129b686a 209 SUPERFAMILY SSF46689 11 74 5.13E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_0022 e853fc4ab14b46b71332089e129b686a 209 SUPERFAMILY SSF48498 86 206 1.96E-16 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily CLOST_0022 e853fc4ab14b46b71332089e129b686a 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 1.3E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_0163 3d84dedfe30a386953f0ad12ef9229a6 359 Pfam PF01938 TRAM domain 297 345 9.4E-7 T 13-10-2018 IPR002792 TRAM domain CLOST_0163 3d84dedfe30a386953f0ad12ef9229a6 359 SUPERFAMILY SSF88723 167 293 6.87E-23 T 13-10-2018 IPR029060 PIN-like domain superfamily CLOST_0163 3d84dedfe30a386953f0ad12ef9229a6 359 Gene3D G3DSA:3.40.50.1010 163 295 8.2E-49 T 13-10-2018 CLOST_0163 3d84dedfe30a386953f0ad12ef9229a6 359 SMART SM00670 165 272 4.1E-9 T 13-10-2018 IPR002716 PIN domain CLOST_0862 590c05933526ea05b6dea2730aedd8b7 263 SUPERFAMILY SSF54001 96 240 1.67E-25 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_0862 590c05933526ea05b6dea2730aedd8b7 263 Pfam PF01841 Transglutaminase-like superfamily 135 234 5.7E-19 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0862 590c05933526ea05b6dea2730aedd8b7 263 SMART SM00460 179 237 2.3E-15 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0862 590c05933526ea05b6dea2730aedd8b7 263 Gene3D G3DSA:3.10.620.30 83 262 1.1E-30 T 13-10-2018 CLOST_1758 c25e92d7b0495607f72cc648e1a49f15 151 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 1 121 8.2E-35 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CLOST_1758 c25e92d7b0495607f72cc648e1a49f15 151 SUPERFAMILY SSF55083 1 142 7.32E-49 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CLOST_1758 c25e92d7b0495607f72cc648e1a49f15 151 Gene3D G3DSA:3.30.70.560 1 149 1.9E-50 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CLOST_1758 c25e92d7b0495607f72cc648e1a49f15 151 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 77 88 - T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CLOST_1758 c25e92d7b0495607f72cc648e1a49f15 151 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 1 121 4.8E-43 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CLOST_2125 4e60a0f07224ffa406a7d8f0b1f73cae 381 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 366 2.8E-116 T 13-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CLOST_2125 4e60a0f07224ffa406a7d8f0b1f73cae 381 Gene3D G3DSA:3.40.50.2000 5 363 1.1E-143 T 13-10-2018 CLOST_2125 4e60a0f07224ffa406a7d8f0b1f73cae 381 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 368 4.0E-154 T 13-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CLOST_2125 4e60a0f07224ffa406a7d8f0b1f73cae 381 SUPERFAMILY SSF53756 1 369 2.64E-131 T 13-10-2018 CLOST_2125 4e60a0f07224ffa406a7d8f0b1f73cae 381 Gene3D G3DSA:3.40.50.2000 192 354 1.1E-143 T 13-10-2018 CLOST_1248 5e7379522f82dedbb4134e9db2b2ecbb 288 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 15 92 6.3E-11 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CLOST_1248 5e7379522f82dedbb4134e9db2b2ecbb 288 SUPERFAMILY SSF56349 4 286 6.18E-25 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CLOST_1248 5e7379522f82dedbb4134e9db2b2ecbb 288 Gene3D G3DSA:1.10.443.10 117 288 2.7E-18 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CLOST_1248 5e7379522f82dedbb4134e9db2b2ecbb 288 Pfam PF00589 Phage integrase family 128 286 1.4E-13 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CLOST_1248 5e7379522f82dedbb4134e9db2b2ecbb 288 Gene3D G3DSA:1.10.150.130 6 104 3.5E-12 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal CLOST_1235 555fa5876a8be0308b322de336716ef2 208 TIGRFAM TIGR00498 lexA: repressor LexA 4 205 9.5E-66 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CLOST_1235 555fa5876a8be0308b322de336716ef2 208 Pfam PF01726 LexA DNA binding domain 4 66 3.2E-22 T 13-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CLOST_1235 555fa5876a8be0308b322de336716ef2 208 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 173 3.7E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CLOST_1235 555fa5876a8be0308b322de336716ef2 208 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 131 3.7E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CLOST_1235 555fa5876a8be0308b322de336716ef2 208 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 132 143 3.7E-9 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CLOST_1235 555fa5876a8be0308b322de336716ef2 208 Gene3D G3DSA:2.10.109.10 90 205 1.2E-41 T 13-10-2018 CLOST_1235 555fa5876a8be0308b322de336716ef2 208 Pfam PF00717 Peptidase S24-like 124 190 1.7E-18 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CLOST_1235 555fa5876a8be0308b322de336716ef2 208 SUPERFAMILY SSF51306 85 204 6.8E-36 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily CLOST_1235 555fa5876a8be0308b322de336716ef2 208 Hamap MF_00015 LexA repressor [lexA]. 4 206 32.187 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CLOST_1235 555fa5876a8be0308b322de336716ef2 208 SUPERFAMILY SSF46785 4 70 1.04E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1235 555fa5876a8be0308b322de336716ef2 208 Gene3D G3DSA:1.10.10.10 4 69 1.6E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2138 018d8f2d3933565cf21463f1233a96bd 323 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 320 1.1E-125 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CLOST_2138 018d8f2d3933565cf21463f1233a96bd 323 Gene3D G3DSA:3.30.540.10 5 311 9.0E-129 T 13-10-2018 CLOST_2138 018d8f2d3933565cf21463f1233a96bd 323 Gene3D G3DSA:3.40.190.90 122 285 9.0E-129 T 13-10-2018 CLOST_2138 018d8f2d3933565cf21463f1233a96bd 323 PIRSF PIRSF004532 1 321 9.4E-136 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CLOST_2138 018d8f2d3933565cf21463f1233a96bd 323 SUPERFAMILY SSF56655 1 314 1.5E-103 T 13-10-2018 CLOST_2138 018d8f2d3933565cf21463f1233a96bd 323 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 311 9.1E-137 T 13-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CLOST_0333 31c29957a73495d2c3e4dafc42e111d7 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 153 28.203 T 13-10-2018 IPR033747 Class I PurE CLOST_0333 31c29957a73495d2c3e4dafc42e111d7 162 Pfam PF00731 AIR carboxylase 2 146 4.0E-57 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CLOST_0333 31c29957a73495d2c3e4dafc42e111d7 162 SUPERFAMILY SSF52255 1 157 1.31E-56 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 CLOST_0333 31c29957a73495d2c3e4dafc42e111d7 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 155 1.0E-56 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CLOST_0333 31c29957a73495d2c3e4dafc42e111d7 162 PIRSF PIRSF001338 1 160 1.3E-63 T 13-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CLOST_0333 31c29957a73495d2c3e4dafc42e111d7 162 Gene3D G3DSA:3.40.50.7700 1 162 4.4E-62 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 CLOST_0333 31c29957a73495d2c3e4dafc42e111d7 162 SMART SM01001 1 149 1.9E-76 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CLOST_2227 3a8fc4d5349618dede4345dc145179e7 291 Pfam PF01925 Sulfite exporter TauE/SafE 5 146 2.4E-9 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CLOST_0453 3f5738a0f47d790e1a3752d1b6fc6489 378 Pfam PF12704 MacB-like periplasmic core domain 1 218 9.8E-31 T 13-10-2018 IPR025857 MacB-like periplasmic core domain CLOST_0453 3f5738a0f47d790e1a3752d1b6fc6489 378 Pfam PF02687 FtsX-like permease family 284 371 4.0E-15 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CLOST_1784 4f1d08cc4e1f4b50cc89b013c5aa01d1 427 Gene3D G3DSA:3.90.226.10 19 224 2.2E-40 T 13-10-2018 CLOST_1784 4f1d08cc4e1f4b50cc89b013c5aa01d1 427 SUPERFAMILY SSF52096 5 184 1.99E-22 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_1784 4f1d08cc4e1f4b50cc89b013c5aa01d1 427 Gene3D G3DSA:2.40.50.140 358 427 3.4E-9 T 13-10-2018 CLOST_1784 4f1d08cc4e1f4b50cc89b013c5aa01d1 427 SUPERFAMILY SSF141322 365 423 3.27E-5 T 13-10-2018 CLOST_1784 4f1d08cc4e1f4b50cc89b013c5aa01d1 427 Pfam PF01957 NfeD-like C-terminal, partner-binding 277 424 4.8E-19 T 13-10-2018 IPR002810 NfeD-like, C-terminal domain CLOST_1911 629779d005de94c8dc8bb2daf322fab8 328 Gene3D G3DSA:3.60.15.10 2 259 2.0E-55 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1911 629779d005de94c8dc8bb2daf322fab8 328 SUPERFAMILY SSF56281 2 313 7.47E-53 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1911 629779d005de94c8dc8bb2daf322fab8 328 SMART SM00849 23 231 1.5E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1911 629779d005de94c8dc8bb2daf322fab8 328 Pfam PF00753 Metallo-beta-lactamase superfamily 25 94 2.4E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1911 629779d005de94c8dc8bb2daf322fab8 328 Pfam PF00753 Metallo-beta-lactamase superfamily 158 231 8.7E-10 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0997 575a8f891961758b931105c5f4c196f6 202 SUPERFAMILY SSF51735 1 116 1.05E-11 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_0997 575a8f891961758b931105c5f4c196f6 202 SUPERFAMILY SSF75615 113 192 2.88E-10 T 13-10-2018 CLOST_0997 575a8f891961758b931105c5f4c196f6 202 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 188 6.0E-19 T 13-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 CLOST_0997 575a8f891961758b931105c5f4c196f6 202 Pfam PF13241 Putative NAD(P)-binding 1 118 2.7E-18 T 13-10-2018 CLOST_0997 575a8f891961758b931105c5f4c196f6 202 Gene3D G3DSA:3.40.50.720 1 134 9.9E-23 T 13-10-2018 CLOST_2208 e2779aa73856457d0099583986ca08d3 156 Gene3D G3DSA:1.10.455.10 2 156 2.4E-62 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily CLOST_2208 e2779aa73856457d0099583986ca08d3 156 SUPERFAMILY SSF47973 7 149 1.15E-59 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily CLOST_2208 e2779aa73856457d0099583986ca08d3 156 PIRSF PIRSF002122 3 156 3.4E-56 T 13-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CLOST_2208 e2779aa73856457d0099583986ca08d3 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.057 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CLOST_2208 e2779aa73856457d0099583986ca08d3 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 13-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2208 e2779aa73856457d0099583986ca08d3 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.8E-68 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CLOST_2208 e2779aa73856457d0099583986ca08d3 156 Pfam PF00177 Ribosomal protein S7p/S5e 2 149 6.3E-66 T 13-10-2018 IPR023798 Ribosomal protein S7 domain CLOST_1902 12a3808e602913606e9b7de7b3b04543 310 PIRSF PIRSF004486 1 310 1.4E-112 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 CLOST_1902 12a3808e602913606e9b7de7b3b04543 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 310 39.104 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 CLOST_1902 12a3808e602913606e9b7de7b3b04543 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 309 3.6E-121 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 CLOST_1902 12a3808e602913606e9b7de7b3b04543 310 Gene3D G3DSA:3.40.50.150 5 306 5.2E-108 T 13-10-2018 CLOST_1902 12a3808e602913606e9b7de7b3b04543 310 SUPERFAMILY SSF53335 5 310 4.74E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1902 12a3808e602913606e9b7de7b3b04543 310 Pfam PF01795 MraW methylase family 2 309 3.5E-125 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 CLOST_1902 12a3808e602913606e9b7de7b3b04543 310 Gene3D G3DSA:1.10.150.170 111 216 5.2E-108 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 CLOST_1902 12a3808e602913606e9b7de7b3b04543 310 SUPERFAMILY SSF81799 113 214 4.19E-36 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 CLOST_1970 41604537d3d57fa78a2504523f692762 515 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 195 211 3.2E-21 T 13-10-2018 CLOST_1970 41604537d3d57fa78a2504523f692762 515 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 221 235 3.2E-21 T 13-10-2018 CLOST_1970 41604537d3d57fa78a2504523f692762 515 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 294 306 3.2E-21 T 13-10-2018 CLOST_1970 41604537d3d57fa78a2504523f692762 515 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 332 356 3.2E-21 T 13-10-2018 CLOST_1970 41604537d3d57fa78a2504523f692762 515 Gene3D G3DSA:3.40.50.150 193 475 1.0E-77 T 13-10-2018 CLOST_1970 41604537d3d57fa78a2504523f692762 515 Pfam PF12161 HsdM N-terminal domain 10 157 1.4E-18 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CLOST_1970 41604537d3d57fa78a2504523f692762 515 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 6 503 1.1E-196 T 13-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 CLOST_1970 41604537d3d57fa78a2504523f692762 515 Pfam PF02384 N-6 DNA Methylase 171 481 5.1E-110 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CLOST_1970 41604537d3d57fa78a2504523f692762 515 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 297 303 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOST_1970 41604537d3d57fa78a2504523f692762 515 SUPERFAMILY SSF53335 9 513 3.34E-121 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1970 41604537d3d57fa78a2504523f692762 515 Gene3D G3DSA:1.20.1260.30 2 189 8.0E-51 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily CLOST_2128 f62debef4081895cd31a38feb4f12b89 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 4.9E-78 T 13-10-2018 CLOST_2128 f62debef4081895cd31a38feb4f12b89 209 Gene3D G3DSA:3.40.50.2020 1 209 8.7E-84 T 13-10-2018 CLOST_2128 f62debef4081895cd31a38feb4f12b89 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 4.7E-92 T 13-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CLOST_2128 f62debef4081895cd31a38feb4f12b89 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 49.025 T 13-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CLOST_2128 f62debef4081895cd31a38feb4f12b89 209 SUPERFAMILY SSF53271 4 207 2.62E-75 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_0700 f5a36104217655d62f4ff19592b40509 440 SMART SM00729 161 370 1.7E-22 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0700 f5a36104217655d62f4ff19592b40509 440 Gene3D G3DSA:3.40.50.280 20 138 1.3E-5 T 13-10-2018 CLOST_0700 f5a36104217655d62f4ff19592b40509 440 Pfam PF04055 Radical SAM superfamily 167 327 7.3E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0700 f5a36104217655d62f4ff19592b40509 440 SUPERFAMILY SSF102114 162 364 1.57E-38 T 13-10-2018 CLOST_0700 f5a36104217655d62f4ff19592b40509 440 Gene3D G3DSA:3.80.30.20 161 363 5.1E-28 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_0700 f5a36104217655d62f4ff19592b40509 440 Pfam PF02310 B12 binding domain 42 122 2.6E-7 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_1936 bb6993e6a4a186a98b017a4d5d9fd7d0 75 Pfam PF00550 Phosphopantetheine attachment site 4 71 4.7E-17 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain CLOST_1936 bb6993e6a4a186a98b017a4d5d9fd7d0 75 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 34 74 5.0E-7 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CLOST_1936 bb6993e6a4a186a98b017a4d5d9fd7d0 75 Hamap MF_01217 Acyl carrier protein [acpP]. 1 75 18.255 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CLOST_1936 bb6993e6a4a186a98b017a4d5d9fd7d0 75 Gene3D G3DSA:1.10.1200.10 1 75 9.0E-26 T 13-10-2018 IPR036736 ACP-like superfamily CLOST_1936 bb6993e6a4a186a98b017a4d5d9fd7d0 75 SUPERFAMILY SSF47336 2 74 4.32E-22 T 13-10-2018 IPR036736 ACP-like superfamily CLOST_1936 bb6993e6a4a186a98b017a4d5d9fd7d0 75 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 75 1.4E-22 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 SUPERFAMILY SSF53150 114 271 1.7E-19 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Pfam PF01624 MutS domain I 5 116 1.5E-45 T 13-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Gene3D G3DSA:1.10.1420.10 392 528 3.5E-83 T 13-10-2018 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Gene3D G3DSA:3.30.420.110 124 266 9.4E-11 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 SUPERFAMILY SSF52540 560 791 9.69E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Gene3D G3DSA:3.40.1170.10 1 118 2.1E-50 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 SUPERFAMILY SSF55271 2 112 2.49E-42 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 849 2.9E-269 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Pfam PF05188 MutS domain II 134 241 3.8E-5 T 13-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 681 697 - T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 SMART SM00533 275 584 3.2E-81 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 PIRSF PIRSF037677 1 217 2.0E-36 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 PIRSF PIRSF037677 212 837 1.5E-134 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 SMART SM00534 600 787 4.6E-110 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 SUPERFAMILY SSF48334 258 559 3.79E-75 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Gene3D G3DSA:3.40.50.300 561 852 2.8E-100 T 13-10-2018 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Pfam PF05192 MutS domain III 261 552 2.0E-37 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 844 22.383 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Pfam PF05190 MutS family domain IV 420 511 3.8E-25 T 13-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Gene3D G3DSA:1.10.1420.10 267 555 3.5E-83 T 13-10-2018 CLOST_1228 2b6385384f83b0b67d39c2ef61562829 853 Pfam PF00488 MutS domain V 603 790 1.1E-83 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CLOST_0990 d0eb62bdf306df4f9d03b75b6d712e73 193 Gene3D G3DSA:3.40.50.150 1 193 2.1E-48 T 13-10-2018 CLOST_0990 d0eb62bdf306df4f9d03b75b6d712e73 193 SUPERFAMILY SSF53335 6 164 8.52E-20 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0990 d0eb62bdf306df4f9d03b75b6d712e73 193 Pfam PF03602 Conserved hypothetical protein 95 31 135 1.3E-7 T 13-10-2018 CLOST_0990 d0eb62bdf306df4f9d03b75b6d712e73 193 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 13 140 1.9E-29 T 13-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 CLOST_1865 446a148483fa35a603259f3bd0cd3a6a 319 PIRSF PIRSF035875 6 302 1.1E-76 T 13-10-2018 IPR017039 Virulence factor BrkB CLOST_1865 446a148483fa35a603259f3bd0cd3a6a 319 Pfam PF03631 Virulence factor BrkB 30 279 3.1E-61 T 13-10-2018 IPR017039 Virulence factor BrkB CLOST_1865 446a148483fa35a603259f3bd0cd3a6a 319 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 22 280 1.0E-41 T 13-10-2018 IPR017039 Virulence factor BrkB CLOST_1385 bafb9006264628e11426f2ffb48e80f7 126 Gene3D G3DSA:3.10.129.10 1 126 4.8E-36 T 13-10-2018 CLOST_1385 bafb9006264628e11426f2ffb48e80f7 126 SUPERFAMILY SSF54637 6 125 4.52E-15 T 13-10-2018 IPR029069 HotDog domain superfamily CLOST_1385 bafb9006264628e11426f2ffb48e80f7 126 Pfam PF03061 Thioesterase superfamily 19 82 2.8E-5 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 ProSitePatterns PS00113 Adenylate kinase signature. 91 102 - T 13-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 Pfam PF05191 Adenylate kinase, active site lid 137 172 1.6E-18 T 13-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 Hamap MF_00235 Adenylate kinase [adk]. 11 223 52.127 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 TIGRFAM TIGR01351 adk: adenylate kinase 12 222 2.9E-84 T 13-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 SUPERFAMILY SSF52540 10 223 2.72E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 Gene3D G3DSA:3.40.50.300 3 223 1.9E-85 T 13-10-2018 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 Pfam PF00406 Adenylate kinase 15 200 4.5E-58 T 13-10-2018 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 PRINTS PR00094 Adenylate kinase signature 91 107 1.1E-34 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 PRINTS PR00094 Adenylate kinase signature 42 56 1.1E-34 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 PRINTS PR00094 Adenylate kinase signature 187 201 1.1E-34 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 PRINTS PR00094 Adenylate kinase signature 14 27 1.1E-34 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CLOST_2177 d3124254e590920c8fd2c62e81b65a2a 226 PRINTS PR00094 Adenylate kinase signature 170 185 1.1E-34 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CLOST_1303 dbed0640a15c024efbf9487e75d60a26 211 SMART SM00849 12 188 2.6E-43 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1303 dbed0640a15c024efbf9487e75d60a26 211 SUPERFAMILY SSF56281 8 209 2.36E-55 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1303 dbed0640a15c024efbf9487e75d60a26 211 Gene3D G3DSA:3.60.15.10 1 210 1.0E-64 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1303 dbed0640a15c024efbf9487e75d60a26 211 Pfam PF00753 Metallo-beta-lactamase superfamily 9 188 4.0E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0582 3f19fab3c69de5e53f98cf8742cfccc1 309 SUPERFAMILY SSF161098 103 296 5.1E-30 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0582 3f19fab3c69de5e53f98cf8742cfccc1 309 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 84 1.6E-18 T 13-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CLOST_0582 3f19fab3c69de5e53f98cf8742cfccc1 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 309 8.2E-33 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0582 3f19fab3c69de5e53f98cf8742cfccc1 309 Gene3D G3DSA:1.10.3720.10 99 304 9.5E-23 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1978 b580f8c9ee9d54933a427f598e07ccb2 329 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 313 1.8E-39 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CLOST_1978 b580f8c9ee9d54933a427f598e07ccb2 329 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 9 320 1.5E-96 T 13-10-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 CLOST_1978 b580f8c9ee9d54933a427f598e07ccb2 329 PIRSF PIRSF006278 1 328 9.6E-87 T 13-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CLOST_1978 b580f8c9ee9d54933a427f598e07ccb2 329 Gene3D G3DSA:3.40.50.1100 46 151 2.6E-103 T 13-10-2018 CLOST_1978 b580f8c9ee9d54933a427f598e07ccb2 329 Gene3D G3DSA:3.40.50.1100 8 317 2.6E-103 T 13-10-2018 CLOST_1978 b580f8c9ee9d54933a427f598e07ccb2 329 SUPERFAMILY SSF53686 8 319 3.4E-74 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 Pfam PF06445 GyrI-like small molecule binding domain 128 288 5.4E-25 T 13-10-2018 IPR029442 GyrI-like small molecule binding domain CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 SUPERFAMILY SSF55136 128 290 1.05E-27 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 Gene3D G3DSA:3.20.80.10 128 291 4.6E-36 T 13-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 SUPERFAMILY SSF46689 7 55 2.11E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 Gene3D G3DSA:1.10.10.60 2 57 3.8E-15 T 13-10-2018 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 6.5E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 6.5E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 Gene3D G3DSA:1.10.10.60 58 116 4.0E-14 T 13-10-2018 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 Pfam PF12833 Helix-turn-helix domain 29 105 1.6E-17 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 SUPERFAMILY SSF46689 57 111 6.27E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 SMART SM00342 21 104 2.5E-24 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CLOST_0715 62b5fadfe104e9eed41a2b4d91414de8 291 SMART SM00871 128 288 2.2E-29 T 13-10-2018 IPR010499 Bacterial transcription activator, effector binding CLOST_1875 b64bd5529dddebf34d555643a6d7e389 443 PIRSF PIRSF006603 1 438 5.4E-91 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_1875 b64bd5529dddebf34d555643a6d7e389 443 Pfam PF01554 MatE 20 180 4.7E-29 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_1875 b64bd5529dddebf34d555643a6d7e389 443 Pfam PF01554 MatE 241 402 9.8E-22 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_1875 b64bd5529dddebf34d555643a6d7e389 443 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 411 6.0E-66 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0600 6a4992b3ffbc7a5af405d36d8d7bebae 542 Gene3D G3DSA:1.20.58.220 328 438 5.9E-17 T 13-10-2018 IPR038078 PhoU-like domain superfamily CLOST_0600 6a4992b3ffbc7a5af405d36d8d7bebae 542 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 5 312 1.4E-74 T 13-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CLOST_0600 6a4992b3ffbc7a5af405d36d8d7bebae 542 Gene3D G3DSA:1.20.58.220 439 540 3.6E-18 T 13-10-2018 IPR038078 PhoU-like domain superfamily CLOST_0600 6a4992b3ffbc7a5af405d36d8d7bebae 542 Pfam PF01895 PhoU domain 448 532 1.9E-12 T 13-10-2018 IPR026022 PhoU domain CLOST_0600 6a4992b3ffbc7a5af405d36d8d7bebae 542 Pfam PF01895 PhoU domain 345 428 4.0E-12 T 13-10-2018 IPR026022 PhoU domain CLOST_0600 6a4992b3ffbc7a5af405d36d8d7bebae 542 SUPERFAMILY SSF109755 330 535 1.26E-49 T 13-10-2018 CLOST_0600 6a4992b3ffbc7a5af405d36d8d7bebae 542 Pfam PF02690 Na+/Pi-cotransporter 144 258 1.7E-18 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CLOST_0600 6a4992b3ffbc7a5af405d36d8d7bebae 542 Pfam PF02690 Na+/Pi-cotransporter 15 150 2.1E-54 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 SUPERFAMILY SSF54211 8 170 1.14E-36 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 Pfam PF01078 Magnesium chelatase, subunit ChlI 193 353 3.9E-68 T 13-10-2018 IPR000523 Magnesium chelatase ChlI domain CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 320 333 2.8E-5 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 212 227 2.8E-5 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 292 306 2.8E-5 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 143 2.3E-44 T 13-10-2018 CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 Gene3D G3DSA:3.30.230.10 5 172 3.6E-20 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 353 2.5E-126 T 13-10-2018 IPR004482 Mg chelatase-related protein CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 SUPERFAMILY SSF52540 193 353 2.02E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1569 15a34f8689c5496fcf8305b2d6362791 354 Gene3D G3DSA:3.40.50.300 190 352 3.0E-35 T 13-10-2018 CLOST_0130 db655a0df4d6416a4b8112e94fda3028 526 Gene3D G3DSA:3.40.50.2300 32 182 3.1E-13 T 13-10-2018 CLOST_0130 db655a0df4d6416a4b8112e94fda3028 526 Pfam PF11849 Domain of unknown function (DUF3369) 154 326 4.4E-37 T 13-10-2018 IPR021800 Domain of unknown function DUF3369 CLOST_0130 db655a0df4d6416a4b8112e94fda3028 526 Pfam PF13487 HD domain 403 466 2.7E-18 T 13-10-2018 CLOST_0130 db655a0df4d6416a4b8112e94fda3028 526 Gene3D G3DSA:1.10.3210.10 328 526 1.2E-71 T 13-10-2018 CLOST_0130 db655a0df4d6416a4b8112e94fda3028 526 SUPERFAMILY SSF52172 30 161 1.17E-9 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0130 db655a0df4d6416a4b8112e94fda3028 526 SMART SM00471 347 484 1.0E-8 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0130 db655a0df4d6416a4b8112e94fda3028 526 SUPERFAMILY SSF109604 338 515 8.8E-37 T 13-10-2018 CLOST_0130 db655a0df4d6416a4b8112e94fda3028 526 Pfam PF00072 Response regulator receiver domain 34 142 1.7E-5 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2478 7e355c3818ce7a72591af486b41e6127 241 Pfam PF07722 Peptidase C26 4 219 1.6E-68 T 13-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CLOST_2478 7e355c3818ce7a72591af486b41e6127 241 SUPERFAMILY SSF52317 2 239 9.17E-39 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_2478 7e355c3818ce7a72591af486b41e6127 241 Gene3D G3DSA:3.40.50.880 2 241 1.1E-78 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0085 557b08e741d52f67646c0141fffec02e 321 Gene3D G3DSA:3.40.50.300 1 321 8.1E-91 T 13-10-2018 CLOST_0085 557b08e741d52f67646c0141fffec02e 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 1.2E-15 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0085 557b08e741d52f67646c0141fffec02e 321 SMART SM00382 33 232 1.8E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0085 557b08e741d52f67646c0141fffec02e 321 SUPERFAMILY SSF52540 4 254 2.32E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0085 557b08e741d52f67646c0141fffec02e 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.1E-20 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0085 557b08e741d52f67646c0141fffec02e 321 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0085 557b08e741d52f67646c0141fffec02e 321 Pfam PF00005 ABC transporter 24 182 3.9E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0539 2e14276d8ae734a51a037b7f73402a8f 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 500 1.2E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0539 2e14276d8ae734a51a037b7f73402a8f 503 SUPERFAMILY SSF55874 343 499 6.81E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0539 2e14276d8ae734a51a037b7f73402a8f 503 Gene3D G3DSA:3.30.565.10 355 502 1.5E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0539 2e14276d8ae734a51a037b7f73402a8f 503 Pfam PF06580 Histidine kinase 289 367 1.0E-25 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CLOST_0539 2e14276d8ae734a51a037b7f73402a8f 503 Gene3D G3DSA:1.20.1480.50 166 265 3.6E-14 T 13-10-2018 CLOST_0539 2e14276d8ae734a51a037b7f73402a8f 503 SUPERFAMILY SSF158472 207 256 7.85E-8 T 13-10-2018 CLOST_0637 741a4b705dedfb528ffde00afcf397f3 250 Gene3D G3DSA:2.20.25.110 145 208 4.1E-66 T 13-10-2018 CLOST_0637 741a4b705dedfb528ffde00afcf397f3 250 Pfam PF13649 Methyltransferase domain 41 137 3.5E-19 T 13-10-2018 CLOST_0637 741a4b705dedfb528ffde00afcf397f3 250 Gene3D G3DSA:3.40.50.150 10 247 4.1E-66 T 13-10-2018 CLOST_0637 741a4b705dedfb528ffde00afcf397f3 250 SUPERFAMILY SSF53335 4 249 1.02E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0965 7b71a53ed9010039c7b958690a318744 406 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CLOST_0965 7b71a53ed9010039c7b958690a318744 406 PIRSF PIRSF037215 1 406 2.4E-178 T 13-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CLOST_0965 7b71a53ed9010039c7b958690a318744 406 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 138 177 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CLOST_0965 7b71a53ed9010039c7b958690a318744 406 Gene3D G3DSA:3.30.70.360 209 319 2.2E-177 T 13-10-2018 CLOST_0965 7b71a53ed9010039c7b958690a318744 406 Gene3D G3DSA:3.40.630.10 4 399 2.2E-177 T 13-10-2018 CLOST_0965 7b71a53ed9010039c7b958690a318744 406 Pfam PF07687 Peptidase dimerisation domain 206 306 5.5E-8 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain CLOST_0965 7b71a53ed9010039c7b958690a318744 406 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 405 1.7E-163 T 13-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CLOST_0965 7b71a53ed9010039c7b958690a318744 406 SUPERFAMILY SSF55031 209 320 3.56E-32 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain CLOST_0965 7b71a53ed9010039c7b958690a318744 406 SUPERFAMILY SSF53187 1 406 5.8E-81 T 13-10-2018 CLOST_0965 7b71a53ed9010039c7b958690a318744 406 Hamap MF_00550 Peptidase T [pepT]. 1 404 53.476 T 13-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CLOST_0965 7b71a53ed9010039c7b958690a318744 406 Pfam PF01546 Peptidase family M20/M25/M40 139 402 1.8E-12 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 CLOST_2391 22bb8fb804f0d8d1908f536dcf901744 747 Pfam PF01228 Glycine radical 621 728 7.5E-41 T 13-10-2018 IPR001150 Glycine radical domain GO:0003824 CLOST_2391 22bb8fb804f0d8d1908f536dcf901744 747 Gene3D G3DSA:3.20.70.20 1 747 2.4E-287 T 13-10-2018 CLOST_2391 22bb8fb804f0d8d1908f536dcf901744 747 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 3 746 0.0 T 13-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CLOST_2391 22bb8fb804f0d8d1908f536dcf901744 747 SUPERFAMILY SSF51998 1 745 7.78E-266 T 13-10-2018 CLOST_2391 22bb8fb804f0d8d1908f536dcf901744 747 ProSitePatterns PS00850 Glycine radical domain signature. 717 725 - T 13-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CLOST_2391 22bb8fb804f0d8d1908f536dcf901744 747 Pfam PF02901 Pyruvate formate lyase-like 15 605 4.1E-192 T 13-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CLOST_2391 22bb8fb804f0d8d1908f536dcf901744 747 PIRSF PIRSF000379 1 747 0.0 T 13-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CLOST_0548 3d3d8aa970876a5d35a8438ad06b6a5f 322 Pfam PF02603 HPr Serine kinase N terminus 19 142 2.5E-38 T 13-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CLOST_0548 3d3d8aa970876a5d35a8438ad06b6a5f 322 SUPERFAMILY SSF75138 17 146 1.02E-32 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily CLOST_0548 3d3d8aa970876a5d35a8438ad06b6a5f 322 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 18 321 39.144 T 13-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CLOST_0548 3d3d8aa970876a5d35a8438ad06b6a5f 322 SUPERFAMILY SSF53795 148 313 1.62E-40 T 13-10-2018 CLOST_0548 3d3d8aa970876a5d35a8438ad06b6a5f 322 Pfam PF07475 HPr Serine kinase C-terminal domain 146 313 4.1E-71 T 13-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CLOST_0548 3d3d8aa970876a5d35a8438ad06b6a5f 322 Gene3D G3DSA:3.40.1390.20 18 144 1.1E-36 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily CLOST_0548 3d3d8aa970876a5d35a8438ad06b6a5f 322 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 19 317 1.4E-111 T 13-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CLOST_0548 3d3d8aa970876a5d35a8438ad06b6a5f 322 Gene3D G3DSA:3.40.50.300 145 322 4.5E-73 T 13-10-2018 CLOST_1788 2df1731e3ac23519d1a583b3c6087a8d 113 Gene3D G3DSA:3.30.428.10 1 113 1.3E-38 T 13-10-2018 IPR036265 HIT-like superfamily CLOST_1788 2df1731e3ac23519d1a583b3c6087a8d 113 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 13-10-2018 IPR019808 Histidine triad, conserved site CLOST_1788 2df1731e3ac23519d1a583b3c6087a8d 113 PRINTS PR00332 Histidine triad family signature 26 44 1.1E-18 T 13-10-2018 IPR001310 Histidine triad (HIT) protein CLOST_1788 2df1731e3ac23519d1a583b3c6087a8d 113 PRINTS PR00332 Histidine triad family signature 93 103 1.1E-18 T 13-10-2018 IPR001310 Histidine triad (HIT) protein CLOST_1788 2df1731e3ac23519d1a583b3c6087a8d 113 PRINTS PR00332 Histidine triad family signature 5 21 1.1E-18 T 13-10-2018 IPR001310 Histidine triad (HIT) protein CLOST_1788 2df1731e3ac23519d1a583b3c6087a8d 113 Pfam PF01230 HIT domain 12 107 5.2E-25 T 13-10-2018 IPR001310 Histidine triad (HIT) protein CLOST_1788 2df1731e3ac23519d1a583b3c6087a8d 113 SUPERFAMILY SSF54197 1 112 4.95E-35 T 13-10-2018 IPR036265 HIT-like superfamily CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 SUPERFAMILY SSF141868 429 667 1.7E-76 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 SMART SM00091 133 199 2.3E-9 T 13-10-2018 IPR000014 PAS domain CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 Gene3D G3DSA:3.30.450.20 130 257 2.4E-20 T 13-10-2018 CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 SMART SM00267 248 414 5.1E-24 T 13-10-2018 IPR000160 GGDEF domain CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 SUPERFAMILY SSF55785 138 250 3.66E-20 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 Pfam PF00990 Diguanylate cyclase, GGDEF domain 259 408 1.2E-29 T 13-10-2018 IPR000160 GGDEF domain CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 Pfam PF00563 EAL domain 430 660 2.2E-66 T 13-10-2018 IPR001633 EAL domain CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 130 254 2.7E-20 T 13-10-2018 IPR000014 PAS domain CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 258 411 7.6E-26 T 13-10-2018 IPR000160 GGDEF domain CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 SMART SM00052 424 665 3.8E-85 T 13-10-2018 IPR001633 EAL domain CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 Pfam PF13426 PAS domain 150 246 3.5E-9 T 13-10-2018 IPR000014 PAS domain CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 Gene3D G3DSA:3.20.20.450 426 670 9.5E-82 T 13-10-2018 IPR035919 EAL domain superfamily CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 Gene3D G3DSA:3.30.70.270 258 425 3.6E-36 T 13-10-2018 CLOST_0769 6544604c865589034d35bc7ecdf9cac5 671 SUPERFAMILY SSF55073 264 415 3.45E-31 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0879 fa8156f6689a84324e1e7ff2c6bc2fe7 289 Gene3D G3DSA:1.10.3720.10 76 279 3.0E-21 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0879 fa8156f6689a84324e1e7ff2c6bc2fe7 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 277 1.5E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0879 fa8156f6689a84324e1e7ff2c6bc2fe7 289 SUPERFAMILY SSF161098 82 272 1.31E-25 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0714 545983ceeb2caddc5493b342a0da06a5 324 SUPERFAMILY SSF51556 1 323 8.43E-66 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_0714 545983ceeb2caddc5493b342a0da06a5 324 Gene3D G3DSA:3.20.20.140 1 324 7.2E-93 T 13-10-2018 CLOST_0714 545983ceeb2caddc5493b342a0da06a5 324 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 321 1.9E-81 T 13-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CLOST_1590 b388865604f07fd3a430c5b2bd06ad47 485 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 448 1.8E-146 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOST_1590 b388865604f07fd3a430c5b2bd06ad47 485 PRINTS PR00175 Sodium/alanine symporter signature 417 437 8.5E-61 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOST_1590 b388865604f07fd3a430c5b2bd06ad47 485 PRINTS PR00175 Sodium/alanine symporter signature 176 194 8.5E-61 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOST_1590 b388865604f07fd3a430c5b2bd06ad47 485 PRINTS PR00175 Sodium/alanine symporter signature 295 313 8.5E-61 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOST_1590 b388865604f07fd3a430c5b2bd06ad47 485 PRINTS PR00175 Sodium/alanine symporter signature 204 223 8.5E-61 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOST_1590 b388865604f07fd3a430c5b2bd06ad47 485 PRINTS PR00175 Sodium/alanine symporter signature 86 108 8.5E-61 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOST_1590 b388865604f07fd3a430c5b2bd06ad47 485 PRINTS PR00175 Sodium/alanine symporter signature 353 375 8.5E-61 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOST_1590 b388865604f07fd3a430c5b2bd06ad47 485 Pfam PF01235 Sodium:alanine symporter family 51 459 2.8E-159 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CLOST_0929 80d8c7cc55ed4524adb92f09fb56b368 267 Pfam PF11495 Archaeal transcriptional regulator TrmB 110 228 5.2E-7 T 13-10-2018 IPR021586 Transcription regulator TrmB, C-terminal CLOST_0929 80d8c7cc55ed4524adb92f09fb56b368 267 SUPERFAMILY SSF46785 4 98 5.09E-8 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0929 80d8c7cc55ed4524adb92f09fb56b368 267 Gene3D G3DSA:1.10.10.10 3 103 5.1E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0929 80d8c7cc55ed4524adb92f09fb56b368 267 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 76 2.6E-21 T 13-10-2018 IPR002831 Transcription regulator TrmB, N-terminal CLOST_1840 74650eeb70c5e50e4dae4af0d8725995 188 Gene3D G3DSA:3.40.50.150 1 188 3.3E-59 T 13-10-2018 CLOST_1840 74650eeb70c5e50e4dae4af0d8725995 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 183 1.2E-49 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CLOST_1840 74650eeb70c5e50e4dae4af0d8725995 188 PIRSF PIRSF004553 1 185 2.5E-52 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CLOST_1840 74650eeb70c5e50e4dae4af0d8725995 188 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 118 124 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOST_1840 74650eeb70c5e50e4dae4af0d8725995 188 Pfam PF03602 Conserved hypothetical protein 95 1 182 8.5E-56 T 13-10-2018 CLOST_1840 74650eeb70c5e50e4dae4af0d8725995 188 SUPERFAMILY SSF53335 1 182 5.53E-48 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_2147 da2dabf1f21ba51922a4f51a10ede5a1 231 Gene3D G3DSA:3.40.50.300 4 218 2.1E-45 T 13-10-2018 CLOST_2147 da2dabf1f21ba51922a4f51a10ede5a1 231 SUPERFAMILY SSF52540 5 222 1.05E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2147 da2dabf1f21ba51922a4f51a10ede5a1 231 Pfam PF02223 Thymidylate kinase 10 201 2.4E-16 T 13-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 CLOST_2094 e08ffa1df4b2b69eced8880351166401 224 SUPERFAMILY SSF52540 5 220 1.33E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2094 e08ffa1df4b2b69eced8880351166401 224 Gene3D G3DSA:3.40.50.300 3 224 1.5E-55 T 13-10-2018 CLOST_2094 e08ffa1df4b2b69eced8880351166401 224 SMART SM00382 32 217 3.3E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2094 e08ffa1df4b2b69eced8880351166401 224 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2094 e08ffa1df4b2b69eced8880351166401 224 Pfam PF00005 ABC transporter 25 169 2.8E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 Pfam PF00255 Glutathione peroxidase 3 109 1.4E-43 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 PIRSF PIRSF000303 1 181 1.0E-65 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 Gene3D G3DSA:3.40.30.10 1 181 5.7E-73 T 13-10-2018 CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 13-10-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 SUPERFAMILY SSF52833 1 181 6.61E-62 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 13-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.1E-19 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 PRINTS PR01011 Glutathione peroxidase family signature 145 154 1.1E-19 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CLOST_0978 6cfd0aea56cf401fe32e1b04cb67d7b3 181 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.1E-19 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CLOST_2590 67101cfbee05b14a44fce759197c1385 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 13-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2590 67101cfbee05b14a44fce759197c1385 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.543 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2590 67101cfbee05b14a44fce759197c1385 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 3.0E-20 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2590 67101cfbee05b14a44fce759197c1385 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 4 27 4.0E-5 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2590 67101cfbee05b14a44fce759197c1385 45 Pfam PF00468 Ribosomal protein L34 3 45 1.4E-21 T 13-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 Gene3D G3DSA:1.10.1160.10 269 347 1.1E-31 T 13-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 SUPERFAMILY SSF50715 348 555 2.93E-69 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 348 535 1.2E-61 T 13-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 SUPERFAMILY SSF52374 36 354 7.41E-95 T 13-10-2018 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 37 558 7.5E-225 T 13-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 Gene3D G3DSA:3.90.800.10 109 217 2.0E-104 T 13-10-2018 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 7 556 50.274 T 13-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 PRINTS PR00987 Glutamyl-tRNA synthetase signature 40 52 1.1E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 PRINTS PR00987 Glutamyl-tRNA synthetase signature 69 82 1.1E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 PRINTS PR00987 Glutamyl-tRNA synthetase signature 218 228 1.1E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 Gene3D G3DSA:3.40.50.620 37 253 2.0E-104 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 Gene3D G3DSA:2.40.240.10 348 553 1.1E-76 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 Gene3D G3DSA:2.40.240.10 356 474 1.1E-76 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CLOST_1079 1f1d6cd642e58b49aa9fba2714380923 559 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 36 345 1.3E-108 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 CLOST_1923 791232c3e72391ac607e301368013a83 306 SUPERFAMILY SSF103481 213 295 2.09E-16 T 13-10-2018 CLOST_1923 791232c3e72391ac607e301368013a83 306 Pfam PF00892 EamA-like transporter family 9 140 6.8E-24 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_1923 791232c3e72391ac607e301368013a83 306 Pfam PF00892 EamA-like transporter family 152 292 1.2E-22 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_1923 791232c3e72391ac607e301368013a83 306 SUPERFAMILY SSF103481 42 144 1.83E-14 T 13-10-2018 CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 SUPERFAMILY SSF55681 69 264 2.13E-50 T 13-10-2018 CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 SUPERFAMILY SSF46785 4 57 9.99E-9 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 Gene3D G3DSA:1.10.10.10 1 61 5.0E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 Pfam PF08279 HTH domain 3 56 1.3E-15 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 Pfam PF03099 Biotin/lipoate A/B protein ligase family 85 208 6.2E-17 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 4 317 32.32 T 13-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 Gene3D G3DSA:3.30.930.10 62 269 1.0E-52 T 13-10-2018 CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 Gene3D G3DSA:2.30.30.100 271 317 7.0E-14 T 13-10-2018 CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 SUPERFAMILY SSF50037 272 317 3.66E-7 T 13-10-2018 IPR008988 Transcriptional repressor, C-terminal CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 Pfam PF02237 Biotin protein ligase C terminal domain 271 317 5.8E-8 T 13-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_0946 4a9ae22a4b252a910bbe71b40f37bc84 317 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 316 1.9E-52 T 13-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Gene3D G3DSA:3.40.50.300 302 723 4.9E-142 T 13-10-2018 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Gene3D G3DSA:1.10.150.20 88 141 6.6E-6 T 13-10-2018 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 SUPERFAMILY SSF47781 81 135 3.89E-5 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 2 740 26.825 T 13-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 SUPERFAMILY SSF52540 316 706 3.42E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Pfam PF13604 AAA domain 318 500 6.5E-44 T 13-10-2018 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Pfam PF13538 UvrD-like helicase C-terminal domain 653 701 1.5E-17 T 13-10-2018 IPR027785 UvrD-like helicase C-terminal domain CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Pfam PF14490 Helix-hairpin-helix containing domain 142 230 1.1E-28 T 13-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Gene3D G3DSA:3.40.50.300 480 717 4.9E-142 T 13-10-2018 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Gene3D G3DSA:2.30.30.940 568 654 4.9E-142 T 13-10-2018 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 5 726 1.2E-200 T 13-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 SMART SM00382 331 480 7.2E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Pfam PF14520 Helix-hairpin-helix domain 89 136 8.2E-5 T 13-10-2018 CLOST_2355 b9abe6cc5e203516c0d99f04ae82bbfe 747 Gene3D G3DSA:1.10.10.2220 183 276 1.1E-14 T 13-10-2018 CLOST_0657 0038f6102ba68d29e77a8e372b325990 151 Pfam PF01668 SmpB protein 7 148 4.2E-62 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 CLOST_0657 0038f6102ba68d29e77a8e372b325990 151 SUPERFAMILY SSF74982 3 130 2.22E-52 T 13-10-2018 IPR023620 Small protein B CLOST_0657 0038f6102ba68d29e77a8e372b325990 151 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 8 130 6.0E-45 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 CLOST_0657 0038f6102ba68d29e77a8e372b325990 151 TIGRFAM TIGR00086 smpB: SsrA-binding protein 7 148 9.8E-59 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 CLOST_0657 0038f6102ba68d29e77a8e372b325990 151 Hamap MF_00023 SsrA-binding protein [smpB]. 1 151 73.302 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 CLOST_0657 0038f6102ba68d29e77a8e372b325990 151 Gene3D G3DSA:2.40.280.10 1 126 3.5E-51 T 13-10-2018 IPR023620 Small protein B CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 387 409 4.1E-23 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 71 88 4.1E-23 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 159 168 4.1E-23 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 305 323 4.1E-23 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 9 420 38.184 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 41 286 3.3E-61 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 Gene3D G3DSA:3.20.20.10 28 286 2.0E-145 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 377 390 9.6E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 187 200 9.6E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 276 295 9.6E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 85 9.6E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 SUPERFAMILY SSF51419 21 288 2.33E-74 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 287 377 1.3E-16 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 Gene3D G3DSA:2.40.37.10 10 416 2.0E-145 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 419 8.9E-141 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 53 71 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CLOST_0434 c946ba42431e6354c09290d5338dbd47 421 SUPERFAMILY SSF50621 261 419 3.56E-52 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CLOST_1389 bd413c761f60bba2818d8e85902d981a 163 Gene3D G3DSA:3.40.50.300 1 147 9.4E-34 T 13-10-2018 CLOST_1389 bd413c761f60bba2818d8e85902d981a 163 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 6 136 2.4E-7 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CLOST_1389 bd413c761f60bba2818d8e85902d981a 163 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 1 159 3.9E-69 T 13-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CLOST_1389 bd413c761f60bba2818d8e85902d981a 163 SUPERFAMILY SSF52540 2 146 4.2E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0663 a6563bc20fc24099585583f1b137a87b 411 Pfam PF03606 C4-dicarboxylate anaerobic carrier 3 407 2.7E-122 T 13-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CLOST_0902 02ae42a68a9239aa60fb5fdd1bca4480 502 Pfam PF02156 Glycosyl hydrolase family 26 274 415 2.2E-19 T 13-10-2018 IPR022790 Glycosyl hydrolase family 26 domain GO:0004553 CLOST_0902 02ae42a68a9239aa60fb5fdd1bca4480 502 Gene3D G3DSA:3.20.20.80 208 498 2.8E-68 T 13-10-2018 CLOST_0902 02ae42a68a9239aa60fb5fdd1bca4480 502 SUPERFAMILY SSF51445 284 472 4.78E-43 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily CLOST_2056 5b43c42bc53c3c842ac9c105ba586daa 151 Pfam PF13187 4Fe-4S dicluster domain 10 55 2.8E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2056 5b43c42bc53c3c842ac9c105ba586daa 151 Gene3D G3DSA:3.30.70.20 6 55 9.2E-17 T 13-10-2018 CLOST_2056 5b43c42bc53c3c842ac9c105ba586daa 151 SUPERFAMILY SSF53920 40 145 3.27E-16 T 13-10-2018 IPR009016 Iron hydrogenase CLOST_2056 5b43c42bc53c3c842ac9c105ba586daa 151 Gene3D G3DSA:3.40.50.1780 56 112 9.2E-17 T 13-10-2018 CLOST_2056 5b43c42bc53c3c842ac9c105ba586daa 151 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2056 5b43c42bc53c3c842ac9c105ba586daa 151 SUPERFAMILY SSF54862 6 66 1.72E-16 T 13-10-2018 CLOST_2056 5b43c42bc53c3c842ac9c105ba586daa 151 Gene3D G3DSA:3.40.950.10 113 140 9.2E-17 T 13-10-2018 CLOST_2056 5b43c42bc53c3c842ac9c105ba586daa 151 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 73 145 2.8E-9 T 13-10-2018 IPR004108 Iron hydrogenase, large subunit, C-terminal CLOST_1284 eb3475665de8cbd1ce97f61afbaae99d 421 SUPERFAMILY SSF51556 75 375 9.77E-80 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_1284 eb3475665de8cbd1ce97f61afbaae99d 421 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 414 41.455 T 13-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_1284 eb3475665de8cbd1ce97f61afbaae99d 421 Pfam PF01979 Amidohydrolase family 72 414 7.9E-27 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CLOST_1284 eb3475665de8cbd1ce97f61afbaae99d 421 TIGRFAM TIGR01224 hutI: imidazolonepropionase 36 413 2.3E-141 T 13-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_1284 eb3475665de8cbd1ce97f61afbaae99d 421 SUPERFAMILY SSF51338 34 419 2.16E-19 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_1284 eb3475665de8cbd1ce97f61afbaae99d 421 Gene3D G3DSA:2.30.40.10 8 412 7.7E-166 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_1284 eb3475665de8cbd1ce97f61afbaae99d 421 Gene3D G3DSA:3.20.20.140 76 374 7.7E-166 T 13-10-2018 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 Gene3D G3DSA:1.20.120.640 305 464 3.4E-34 T 13-10-2018 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 SUPERFAMILY SSF47323 339 464 2.62E-33 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 1 464 3.1E-184 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 1.0E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 1.0E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 1.0E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 1.0E-29 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 SMART SM00840 352 416 5.2E-16 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 SUPERFAMILY SSF52374 2 310 8.96E-102 T 13-10-2018 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 465 39.44 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 Pfam PF09190 DALR domain 352 410 8.3E-14 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 311 1.8E-136 T 13-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CLOST_2241 0173e36fcc86bd5490123cdcf1ab54a4 466 Gene3D G3DSA:3.40.50.620 1 303 1.4E-138 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0010 686a2cb5c1b5c489d52f854a2a737faf 106 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 9 104 2.0E-25 T 13-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CLOST_0010 686a2cb5c1b5c489d52f854a2a737faf 106 SUPERFAMILY SSF52091 11 104 1.04E-22 T 13-10-2018 IPR036513 STAS domain superfamily CLOST_0010 686a2cb5c1b5c489d52f854a2a737faf 106 Pfam PF01740 STAS domain 17 102 1.7E-16 T 13-10-2018 IPR002645 STAS domain CLOST_0010 686a2cb5c1b5c489d52f854a2a737faf 106 Gene3D G3DSA:3.30.750.24 5 106 2.8E-23 T 13-10-2018 IPR036513 STAS domain superfamily CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 200 216 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 42 57 3.3E-57 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 Gene3D G3DSA:3.50.50.60 10 307 9.0E-97 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 SUPERFAMILY SSF52833 311 403 1.29E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 Gene3D G3DSA:3.50.50.60 124 249 9.0E-97 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 SUPERFAMILY SSF51905 6 312 5.03E-46 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 Pfam PF00085 Thioredoxin 311 403 3.5E-11 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 298 1.6E-40 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 Gene3D G3DSA:3.40.30.10 308 406 1.8E-14 T 13-10-2018 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.6E-30 T 13-10-2018 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.6E-30 T 13-10-2018 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.6E-30 T 13-10-2018 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.6E-30 T 13-10-2018 CLOST_1438 1a1ce72ea19c6144b275ef1136d91ed6 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.6E-30 T 13-10-2018 CLOST_1322 92425d7893906c18e2956d4ab2f2c6f1 237 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 5 236 1.7E-92 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CLOST_1322 92425d7893906c18e2956d4ab2f2c6f1 237 SUPERFAMILY SSF75625 5 236 1.18E-91 T 13-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CLOST_1322 92425d7893906c18e2956d4ab2f2c6f1 237 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 2 237 33.693 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CLOST_1322 92425d7893906c18e2956d4ab2f2c6f1 237 Pfam PF01709 Transcriptional regulator 6 235 2.7E-96 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CLOST_1322 92425d7893906c18e2956d4ab2f2c6f1 237 Gene3D G3DSA:1.10.10.200 15 78 4.9E-28 T 13-10-2018 IPR017856 Integrase-like, N-terminal CLOST_1322 92425d7893906c18e2956d4ab2f2c6f1 237 Gene3D G3DSA:3.30.70.980 82 234 4.4E-56 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CLOST_1322 92425d7893906c18e2956d4ab2f2c6f1 237 Gene3D G3DSA:3.30.70.980 131 201 4.4E-56 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CLOST_0883 851288865d40a315ec2a9eef384d4444 303 Gene3D G3DSA:2.70.70.10 148 303 1.4E-52 T 13-10-2018 IPR011055 Duplicated hybrid motif CLOST_0883 851288865d40a315ec2a9eef384d4444 303 Pfam PF01551 Peptidase family M23 203 297 1.8E-37 T 13-10-2018 IPR016047 Peptidase M23 CLOST_0883 851288865d40a315ec2a9eef384d4444 303 SUPERFAMILY SSF51261 154 301 3.14E-58 T 13-10-2018 IPR011055 Duplicated hybrid motif CLOST_2520 71f43947dba3dfae3918af46548db768 617 Pfam PF06048 Domain of unknown function (DUF927) 48 296 7.3E-35 T 13-10-2018 IPR009270 Domain of unknown function DUF927 CLOST_1052 d4487be3ff38bc71c1d527c57758ecb2 337 Gene3D G3DSA:3.40.220.10 2 173 8.6E-65 T 13-10-2018 CLOST_1052 d4487be3ff38bc71c1d527c57758ecb2 337 Pfam PF01661 Macro domain 19 131 2.1E-39 T 13-10-2018 IPR002589 Macro domain CLOST_1052 d4487be3ff38bc71c1d527c57758ecb2 337 SMART SM00506 2 131 1.3E-46 T 13-10-2018 IPR002589 Macro domain CLOST_1052 d4487be3ff38bc71c1d527c57758ecb2 337 SUPERFAMILY SSF52949 3 166 6.39E-60 T 13-10-2018 CLOST_0524 b909eb4729d0c1c2dc8550a9c5d92d61 208 PIRSF PIRSF000495 1 201 6.7E-63 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CLOST_0524 b909eb4729d0c1c2dc8550a9c5d92d61 208 Gene3D G3DSA:3.40.50.880 1 206 4.8E-63 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0524 b909eb4729d0c1c2dc8550a9c5d92d61 208 SUPERFAMILY SSF52317 2 200 1.29E-47 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_0524 b909eb4729d0c1c2dc8550a9c5d92d61 208 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 198 1.1E-62 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CLOST_0524 b909eb4729d0c1c2dc8550a9c5d92d61 208 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 198 31.055 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CLOST_0524 b909eb4729d0c1c2dc8550a9c5d92d61 208 Pfam PF00117 Glutamine amidotransferase class-I 4 195 4.0E-20 T 13-10-2018 IPR017926 Glutamine amidotransferase CLOST_0505 d454d68b4d844a4179f7953aea728543 399 Gene3D G3DSA:3.30.9.10 122 341 2.2E-67 T 13-10-2018 CLOST_0505 d454d68b4d844a4179f7953aea728543 399 Gene3D G3DSA:3.50.50.60 29 382 2.2E-67 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0505 d454d68b4d844a4179f7953aea728543 399 SUPERFAMILY SSF51905 28 387 2.59E-40 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0505 d454d68b4d844a4179f7953aea728543 399 Pfam PF01266 FAD dependent oxidoreductase 29 381 2.7E-51 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CLOST_1954 cb9ecff955432b544d5109312462179d 192 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 16 190 6.1E-62 T 13-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 CLOST_1954 cb9ecff955432b544d5109312462179d 192 SUPERFAMILY SSF110391 15 191 4.05E-54 T 13-10-2018 IPR035928 GlpP-like superfamily CLOST_1954 cb9ecff955432b544d5109312462179d 192 PIRSF PIRSF016897 5 192 1.9E-62 T 13-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 CLOST_1954 cb9ecff955432b544d5109312462179d 192 Gene3D G3DSA:3.20.20.400 6 192 1.2E-63 T 13-10-2018 IPR035928 GlpP-like superfamily CLOST_0386 4f08ce1506c83e11a2dcb468a64041f6 350 Gene3D G3DSA:3.40.50.10470 145 335 2.3E-74 T 13-10-2018 CLOST_0386 4f08ce1506c83e11a2dcb468a64041f6 350 Pfam PF01008 Initiation factor 2 subunit family 70 335 4.9E-45 T 13-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CLOST_0386 4f08ce1506c83e11a2dcb468a64041f6 350 Gene3D G3DSA:1.20.120.420 47 144 2.3E-74 T 13-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CLOST_0386 4f08ce1506c83e11a2dcb468a64041f6 350 SUPERFAMILY SSF100950 10 341 8.29E-78 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_0386 4f08ce1506c83e11a2dcb468a64041f6 350 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 334 1.4E-58 T 13-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 SUPERFAMILY SSF53706 6 550 3.01E-110 T 13-10-2018 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 Pfam PF01568 Molydopterin dinucleotide binding domain 565 643 8.4E-12 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 Gene3D G3DSA:2.20.25.90 2 60 1.1E-11 T 13-10-2018 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 Gene3D G3DSA:3.30.2070.10 418 502 4.5E-108 T 13-10-2018 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 Gene3D G3DSA:3.40.50.740 67 464 4.5E-108 T 13-10-2018 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 54 4.7E-7 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 SUPERFAMILY SSF50692 510 648 4.07E-20 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 Gene3D G3DSA:3.40.228.10 132 525 4.5E-108 T 13-10-2018 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 SMART SM00926 1 55 7.2E-10 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 Pfam PF00384 Molybdopterin oxidoreductase 58 459 7.4E-38 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1439 c2e689679d34f0ee79795491859aeda4 651 Gene3D G3DSA:2.40.40.20 535 651 1.5E-16 T 13-10-2018 CLOST_0939 bb461c4aaee2aafcad7df7b8b1ee340c 134 Gene3D G3DSA:3.40.50.280 1 134 4.2E-56 T 13-10-2018 CLOST_0939 bb461c4aaee2aafcad7df7b8b1ee340c 134 SUPERFAMILY SSF52242 2 132 3.27E-47 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0939 bb461c4aaee2aafcad7df7b8b1ee340c 134 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 4 133 5.2E-51 T 13-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CLOST_0939 bb461c4aaee2aafcad7df7b8b1ee340c 134 Pfam PF02310 B12 binding domain 5 108 1.6E-21 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0391 56eb01458c54aa5d2d253cd3482ad972 183 SUPERFAMILY SSF51182 58 183 6.88E-30 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0391 56eb01458c54aa5d2d253cd3482ad972 183 Gene3D G3DSA:1.10.260.40 1 71 4.0E-18 T 13-10-2018 CLOST_0391 56eb01458c54aa5d2d253cd3482ad972 183 SUPERFAMILY SSF47413 2 71 5.35E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_0391 56eb01458c54aa5d2d253cd3482ad972 183 Pfam PF07883 Cupin domain 109 177 3.9E-18 T 13-10-2018 IPR013096 Cupin 2, conserved barrel CLOST_0391 56eb01458c54aa5d2d253cd3482ad972 183 Pfam PF01381 Helix-turn-helix 11 65 7.2E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_0391 56eb01458c54aa5d2d253cd3482ad972 183 SMART SM00530 10 65 1.0E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_0391 56eb01458c54aa5d2d253cd3482ad972 183 Gene3D G3DSA:2.60.120.10 72 178 1.5E-23 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0240 c9827596528bada40c916d50b0b60708 228 Pfam PF00072 Response regulator receiver domain 2 111 1.0E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0240 c9827596528bada40c916d50b0b60708 228 Gene3D G3DSA:3.40.50.2300 1 126 4.5E-34 T 13-10-2018 CLOST_0240 c9827596528bada40c916d50b0b60708 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 2.0E-27 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_0240 c9827596528bada40c916d50b0b60708 228 SUPERFAMILY SSF52172 1 182 4.98E-38 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0240 c9827596528bada40c916d50b0b60708 228 SMART SM00862 147 223 2.3E-27 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_0240 c9827596528bada40c916d50b0b60708 228 SMART SM00448 1 110 2.8E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0240 c9827596528bada40c916d50b0b60708 228 Gene3D G3DSA:1.10.10.10 127 227 3.9E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2097 3ed94975d9aab0c92dbb05018380c61b 344 Gene3D G3DSA:3.40.720.10 218 344 7.5E-16 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CLOST_2097 3ed94975d9aab0c92dbb05018380c61b 344 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 234 322 1.7E-9 T 13-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CLOST_2097 3ed94975d9aab0c92dbb05018380c61b 344 Gene3D G3DSA:3.40.720.10 116 217 8.1E-6 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CLOST_2097 3ed94975d9aab0c92dbb05018380c61b 344 SUPERFAMILY SSF53649 135 325 7.2E-22 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CLOST_0474 6725a8249bdd50c2669fe3b1eeb043c1 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 33.972 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOST_0474 6725a8249bdd50c2669fe3b1eeb043c1 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 185 6.6E-59 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOST_0474 6725a8249bdd50c2669fe3b1eeb043c1 186 SUPERFAMILY SSF53178 1 185 1.31E-65 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 CLOST_0474 6725a8249bdd50c2669fe3b1eeb043c1 186 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 2.4E-55 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CLOST_0474 6725a8249bdd50c2669fe3b1eeb043c1 186 Gene3D G3DSA:3.40.50.1470 1 186 2.5E-68 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 CLOST_0474 6725a8249bdd50c2669fe3b1eeb043c1 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CLOST_0474 6725a8249bdd50c2669fe3b1eeb043c1 186 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CLOST_1367 00cc2e1d9576cd7baf53f5f2cc83c4d6 426 Gene3D G3DSA:3.30.70.2390 339 423 3.5E-9 T 13-10-2018 CLOST_1367 00cc2e1d9576cd7baf53f5f2cc83c4d6 426 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 339 426 2.8E-15 T 13-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CLOST_1367 00cc2e1d9576cd7baf53f5f2cc83c4d6 426 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 74 225 2.0E-42 T 13-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CLOST_1367 00cc2e1d9576cd7baf53f5f2cc83c4d6 426 Gene3D G3DSA:1.10.260.150 34 338 3.4E-80 T 13-10-2018 CLOST_1367 00cc2e1d9576cd7baf53f5f2cc83c4d6 426 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 74 225 2.7E-44 T 13-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CLOST_1453 dee0fa7a3e5916fc489f9dfe604a8ae8 700 SUPERFAMILY SSF53067 11 207 2.4E-22 T 13-10-2018 CLOST_1453 dee0fa7a3e5916fc489f9dfe604a8ae8 700 SMART SM00842 11 207 2.5E-41 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 CLOST_1453 dee0fa7a3e5916fc489f9dfe604a8ae8 700 Gene3D G3DSA:3.30.420.40 14 367 9.7E-40 T 13-10-2018 CLOST_1453 dee0fa7a3e5916fc489f9dfe604a8ae8 700 Gene3D G3DSA:3.90.640.10 246 302 9.7E-40 T 13-10-2018 CLOST_1453 dee0fa7a3e5916fc489f9dfe604a8ae8 700 SUPERFAMILY SSF53067 215 383 8.19E-25 T 13-10-2018 CLOST_1453 dee0fa7a3e5916fc489f9dfe604a8ae8 700 Gene3D G3DSA:3.30.1490.110 89 180 9.7E-40 T 13-10-2018 CLOST_1453 dee0fa7a3e5916fc489f9dfe604a8ae8 700 Gene3D G3DSA:3.30.420.40 208 353 9.7E-40 T 13-10-2018 CLOST_1453 dee0fa7a3e5916fc489f9dfe604a8ae8 700 Pfam PF14450 Cell division protein FtsA 218 353 1.4E-10 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 Gene3D G3DSA:3.50.50.60 139 258 3.4E-70 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 Gene3D G3DSA:3.50.50.60 6 317 3.4E-70 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.5E-36 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 300 1.5E-36 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 388 403 1.5E-36 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 1.5E-36 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 329 350 1.5E-36 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 430 1.5E-36 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.5E-36 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 130 139 1.5E-36 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 434 2.8E-11 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 313 3.6E-43 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.0E-20 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 1.0E-20 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 1.0E-20 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 1.0E-20 T 13-10-2018 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 SUPERFAMILY SSF51905 2 321 9.17E-37 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 Gene3D G3DSA:3.30.390.30 330 438 3.7E-16 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_0380 02c04c6ab287ec43e2d765ee3265baa9 438 SUPERFAMILY SSF55424 330 436 4.98E-16 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CLOST_0274 b6e93abf5f4de1da18fb82d9da1ffe13 408 Gene3D G3DSA:3.20.20.140 77 349 6.8E-98 T 13-10-2018 CLOST_0274 b6e93abf5f4de1da18fb82d9da1ffe13 408 Gene3D G3DSA:2.30.40.10 9 403 6.8E-98 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0274 b6e93abf5f4de1da18fb82d9da1ffe13 408 ProSitePatterns PS00483 Dihydroorotase signature 2. 290 301 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_0274 b6e93abf5f4de1da18fb82d9da1ffe13 408 SUPERFAMILY SSF51556 78 349 2.12E-64 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_0274 b6e93abf5f4de1da18fb82d9da1ffe13 408 SUPERFAMILY SSF51338 7 407 1.34E-12 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0274 b6e93abf5f4de1da18fb82d9da1ffe13 408 Pfam PF01979 Amidohydrolase family 73 401 9.9E-16 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CLOST_1210 0785beb561065dae38c96bc804fdfa5d 450 SUPERFAMILY SSF53850 18 446 8.98E-35 T 13-10-2018 CLOST_1210 0785beb561065dae38c96bc804fdfa5d 450 Gene3D G3DSA:3.40.190.10 55 386 2.4E-41 T 13-10-2018 CLOST_1210 0785beb561065dae38c96bc804fdfa5d 450 Gene3D G3DSA:3.40.190.10 144 435 2.4E-41 T 13-10-2018 CLOST_1210 0785beb561065dae38c96bc804fdfa5d 450 Pfam PF13416 Bacterial extracellular solute-binding protein 56 385 1.1E-43 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein CLOST_0077 fe66c743fe4a788dee703f35e3bfe9b9 288 SUPERFAMILY SSF51726 24 218 2.04E-18 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0077 fe66c743fe4a788dee703f35e3bfe9b9 288 Gene3D G3DSA:3.20.20.210 7 250 5.2E-26 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0077 fe66c743fe4a788dee703f35e3bfe9b9 288 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 13 216 7.5E-19 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CLOST_2580 aa0d1af418a239270fff294cb7e9ef50 240 SUPERFAMILY SSF53335 5 239 7.57E-49 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_2580 aa0d1af418a239270fff294cb7e9ef50 240 Pfam PF02527 rRNA small subunit methyltransferase G 22 202 4.8E-53 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CLOST_2580 aa0d1af418a239270fff294cb7e9ef50 240 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 217 1.4E-54 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CLOST_2580 aa0d1af418a239270fff294cb7e9ef50 240 Gene3D G3DSA:3.40.50.150 1 240 5.1E-84 T 13-10-2018 CLOST_2580 aa0d1af418a239270fff294cb7e9ef50 240 PIRSF PIRSF003078 2 222 9.0E-55 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CLOST_2580 aa0d1af418a239270fff294cb7e9ef50 240 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 15 216 27.587 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CLOST_0956 70f56f393c8525720061aeab9bc52895 782 SUPERFAMILY SSF51998 131 760 1.77E-145 T 13-10-2018 CLOST_0956 70f56f393c8525720061aeab9bc52895 782 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 323 781 2.9E-148 T 13-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 CLOST_0956 70f56f393c8525720061aeab9bc52895 782 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 126 781 4.8E-212 T 13-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 CLOST_0956 70f56f393c8525720061aeab9bc52895 782 Pfam PF03477 ATP cone domain 4 97 8.1E-18 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 Pfam PF07650 KH domain 213 291 1.8E-18 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 173 4.3E-26 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 Gene3D G3DSA:3.40.50.300 8 190 3.1E-44 T 13-10-2018 CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 SUPERFAMILY SSF52540 16 210 8.46E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 Hamap MF_00367 GTPase Era [era]. 11 302 36.714 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 Pfam PF01926 50S ribosome-binding GTPase 16 130 1.3E-25 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 TIGRFAM TIGR00436 era: GTP-binding protein Era 14 285 3.0E-89 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 Gene3D G3DSA:3.30.300.20 191 304 1.1E-43 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta CLOST_1774 8a3a6c7926695e5a6421a6bf1ca6d909 305 SUPERFAMILY SSF54814 187 303 8.5E-41 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CLOST_1542 706a9e351441cf739d201dccd038fef1 466 SUPERFAMILY SSF53335 4 454 1.33E-70 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1542 706a9e351441cf739d201dccd038fef1 466 Gene3D G3DSA:3.40.50.150 3 188 1.5E-43 T 13-10-2018 CLOST_1542 706a9e351441cf739d201dccd038fef1 466 Pfam PF00145 C-5 cytosine-specific DNA methylase 4 455 3.6E-28 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_1542 706a9e351441cf739d201dccd038fef1 466 Gene3D G3DSA:3.90.120.10 391 447 3.2E-6 T 13-10-2018 CLOST_1542 706a9e351441cf739d201dccd038fef1 466 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 108 122 5.9E-10 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_1542 706a9e351441cf739d201dccd038fef1 466 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 3 19 5.9E-10 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_1542 706a9e351441cf739d201dccd038fef1 466 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 165 178 5.9E-10 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 Pfam PF00672 HAMP domain 190 239 2.0E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 30 135 1.9E-18 T 13-10-2018 IPR029095 NarX-like, N-terminal CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 SMART SM00304 189 243 2.0E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 SUPERFAMILY SSF58104 211 547 2.35E-65 T 13-10-2018 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 SMART SM00283 265 547 9.6E-48 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 Gene3D G3DSA:1.20.1480.50 148 248 9.7E-11 T 13-10-2018 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 370 397 3.7E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 3.7E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 24 3.7E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 Gene3D G3DSA:1.10.287.950 251 547 1.6E-59 T 13-10-2018 CLOST_0761 bbf8353939d05a591b24f482c45b2856 548 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 346 500 1.5E-33 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0969 a745c203b7dc5a787e7c58ce179a3790 478 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 473 3.5E-178 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CLOST_0969 a745c203b7dc5a787e7c58ce179a3790 478 Gene3D G3DSA:3.40.50.2000 250 458 6.3E-185 T 13-10-2018 CLOST_0969 a745c203b7dc5a787e7c58ce179a3790 478 Pfam PF08323 Starch synthase catalytic domain 2 237 6.4E-87 T 13-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CLOST_0969 a745c203b7dc5a787e7c58ce179a3790 478 SUPERFAMILY SSF53756 2 476 8.79E-130 T 13-10-2018 CLOST_0969 a745c203b7dc5a787e7c58ce179a3790 478 Hamap MF_00484 Glycogen synthase [glgA]. 1 474 46.15 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CLOST_0969 a745c203b7dc5a787e7c58ce179a3790 478 Gene3D G3DSA:3.40.50.2000 3 472 6.3E-185 T 13-10-2018 CLOST_0969 a745c203b7dc5a787e7c58ce179a3790 478 Pfam PF00534 Glycosyl transferases group 1 290 446 1.5E-11 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 128 1.3E-44 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 13-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 127 5.0E-45 T 13-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 82 90 9.5E-13 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 91 100 9.5E-13 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 9.5E-13 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 Gene3D G3DSA:1.10.1200.120 1 130 8.8E-43 T 13-10-2018 IPR036019 Gated mechanosensitive channel CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 SUPERFAMILY SSF81330 10 123 6.54E-35 T 13-10-2018 IPR036019 Gated mechanosensitive channel CLOST_1596 5bed4526a24882c6acfcdd7f0a453db1 134 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 128 23.509 T 13-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 CLOST_0751 3de8b7b8c2d8332983c0579b98a6afef 524 Pfam PF00990 Diguanylate cyclase, GGDEF domain 352 513 5.1E-40 T 13-10-2018 IPR000160 GGDEF domain CLOST_0751 3de8b7b8c2d8332983c0579b98a6afef 524 Gene3D G3DSA:3.30.70.270 341 520 6.6E-47 T 13-10-2018 CLOST_0751 3de8b7b8c2d8332983c0579b98a6afef 524 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 348 516 9.8E-43 T 13-10-2018 IPR000160 GGDEF domain CLOST_0751 3de8b7b8c2d8332983c0579b98a6afef 524 SUPERFAMILY SSF55073 357 518 1.49E-40 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0751 3de8b7b8c2d8332983c0579b98a6afef 524 Pfam PF08269 Cache domain 171 297 1.6E-16 T 13-10-2018 IPR004010 Double Cache domain 2 CLOST_0751 3de8b7b8c2d8332983c0579b98a6afef 524 SMART SM00267 341 517 4.5E-43 T 13-10-2018 IPR000160 GGDEF domain CLOST_0751 3de8b7b8c2d8332983c0579b98a6afef 524 Gene3D G3DSA:3.30.450.20 171 302 8.9E-25 T 13-10-2018 CLOST_2272 e95181b57b786a6298931316daf46bc0 173 PIRSF PIRSF006578 1 111 1.9E-40 T 13-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E CLOST_2272 e95181b57b786a6298931316daf46bc0 173 PIRSF PIRSF006578 96 172 2.2E-19 T 13-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E CLOST_2272 e95181b57b786a6298931316daf46bc0 173 SUPERFAMILY SSF143555 2 136 4.05E-40 T 13-10-2018 CLOST_2272 e95181b57b786a6298931316daf46bc0 173 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 11 106 9.8E-30 T 13-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain CLOST_2272 e95181b57b786a6298931316daf46bc0 173 Gene3D G3DSA:3.30.1330.130 1 138 1.1E-36 T 13-10-2018 CLOST_1334 4e3e618af4e6d643ab2f35e930d43e32 178 Gene3D G3DSA:3.90.79.10 1 176 1.5E-54 T 13-10-2018 CLOST_1334 4e3e618af4e6d643ab2f35e930d43e32 178 SUPERFAMILY SSF55811 4 172 7.04E-48 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 CLOST_1334 4e3e618af4e6d643ab2f35e930d43e32 178 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 12 171 1.3E-25 T 13-10-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 CLOST_1334 4e3e618af4e6d643ab2f35e930d43e32 178 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CLOST_1334 4e3e618af4e6d643ab2f35e930d43e32 178 Pfam PF00293 NUDIX domain 41 156 4.3E-20 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CLOST_0854 bbdec82777a1bfeeb299b3a5da0ec6d3 197 Pfam PF08241 Methyltransferase domain 39 131 4.1E-14 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CLOST_0854 bbdec82777a1bfeeb299b3a5da0ec6d3 197 Gene3D G3DSA:3.40.50.150 2 184 2.5E-23 T 13-10-2018 CLOST_0854 bbdec82777a1bfeeb299b3a5da0ec6d3 197 SUPERFAMILY SSF53335 20 184 2.84E-19 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 1.5E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 429 1.5E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 1.5E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 1.5E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 319 3.8E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 SUPERFAMILY SSF55874 309 469 9.3E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 SMART SM00388 254 320 4.0E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 Gene3D G3DSA:1.10.287.130 199 316 6.1E-20 T 13-10-2018 CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 SMART SM00387 365 470 2.7E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 SUPERFAMILY SSF47384 239 318 2.16E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 Gene3D G3DSA:3.30.565.10 324 471 1.5E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0870 26e2a197f6a1ceca38fa9e3e13fe6b14 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 467 4.9E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_1283 e0cbfe8f81185239dafc48a4bb5c33ea 214 SUPERFAMILY SSF101262 3 211 4.32E-52 T 13-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CLOST_1283 e0cbfe8f81185239dafc48a4bb5c33ea 214 Gene3D G3DSA:1.20.120.680 7 213 1.8E-62 T 13-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CLOST_1283 e0cbfe8f81185239dafc48a4bb5c33ea 214 Pfam PF04961 Formiminotransferase-cyclodeaminase 8 192 2.5E-58 T 13-10-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CLOST_0477 4670bb7d41e620368d1921b0e57177cd 158 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 1 156 34.36 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0477 4670bb7d41e620368d1921b0e57177cd 158 Gene3D G3DSA:3.30.70.640 1 158 1.0E-64 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0477 4670bb7d41e620368d1921b0e57177cd 158 Pfam PF01967 MoaC family 14 148 2.9E-53 T 13-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0477 4670bb7d41e620368d1921b0e57177cd 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 150 1.7E-63 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0477 4670bb7d41e620368d1921b0e57177cd 158 SUPERFAMILY SSF55040 10 153 2.09E-57 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_1811 9cc30cf6a2a02b3a51842565b2eb7213 70 SUPERFAMILY SSF50800 15 58 1.38E-5 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily CLOST_1811 9cc30cf6a2a02b3a51842565b2eb7213 70 Pfam PF11213 Protein of unknown function (DUF3006) 3 69 1.6E-21 T 13-10-2018 IPR021377 Protein of unknown function DUF3006 CLOST_0613 f14c02a3f4b7c0cd10b1735cdce791bd 316 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 46 313 2.4E-76 T 13-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CLOST_0613 f14c02a3f4b7c0cd10b1735cdce791bd 316 Gene3D G3DSA:1.10.3720.10 85 316 3.4E-32 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0613 f14c02a3f4b7c0cd10b1735cdce791bd 316 SUPERFAMILY SSF161098 62 303 1.2E-36 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0613 f14c02a3f4b7c0cd10b1735cdce791bd 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 309 6.5E-22 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0183 d04ab7ece18cf2e412dc29dedd463c4a 347 PIRSF PIRSF006268 1 339 2.3E-101 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 CLOST_0183 d04ab7ece18cf2e412dc29dedd463c4a 347 Pfam PF02424 ApbE family 43 314 1.7E-79 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 CLOST_0183 d04ab7ece18cf2e412dc29dedd463c4a 347 SUPERFAMILY SSF143631 37 333 6.1E-88 T 13-10-2018 IPR003374 ApbE-like superfamily CLOST_0183 d04ab7ece18cf2e412dc29dedd463c4a 347 Gene3D G3DSA:3.10.520.20 27 345 3.8E-104 T 13-10-2018 CLOST_0542 ff3a2bfbd8bd0e44885f40a53f410b7c 363 Gene3D G3DSA:3.40.50.2300 29 334 3.3E-125 T 13-10-2018 CLOST_0542 ff3a2bfbd8bd0e44885f40a53f410b7c 363 Pfam PF13407 Periplasmic binding protein domain 29 314 4.1E-55 T 13-10-2018 IPR025997 Periplasmic binding protein CLOST_0542 ff3a2bfbd8bd0e44885f40a53f410b7c 363 Gene3D G3DSA:3.40.50.2300 131 355 3.3E-125 T 13-10-2018 CLOST_0542 ff3a2bfbd8bd0e44885f40a53f410b7c 363 SUPERFAMILY SSF53822 29 346 3.93E-52 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_2107 83849723b90604998b7ad992c163f63c 367 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 3 312 3.5E-79 T 13-10-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB CLOST_2107 83849723b90604998b7ad992c163f63c 367 Pfam PF04230 Polysaccharide pyruvyl transferase 14 299 9.4E-48 T 13-10-2018 IPR007345 Polysaccharide pyruvyl transferase CLOST_0470 171f564faef5f2a58fdabfa31a866a70 277 SUPERFAMILY SSF46785 2 73 3.81E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0470 171f564faef5f2a58fdabfa31a866a70 277 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 261 1.1E-98 T 13-10-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CLOST_0470 171f564faef5f2a58fdabfa31a866a70 277 Pfam PF00156 Phosphoribosyl transferase domain 109 262 2.8E-20 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOST_0470 171f564faef5f2a58fdabfa31a866a70 277 Gene3D G3DSA:1.10.10.10 1 73 2.5E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0470 171f564faef5f2a58fdabfa31a866a70 277 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 2.3E-29 T 13-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CLOST_0470 171f564faef5f2a58fdabfa31a866a70 277 SUPERFAMILY SSF53271 85 237 2.62E-32 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_0470 171f564faef5f2a58fdabfa31a866a70 277 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 12 73 3.0E-18 T 13-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CLOST_0470 171f564faef5f2a58fdabfa31a866a70 277 Gene3D G3DSA:3.40.50.2020 74 267 9.4E-48 T 13-10-2018 CLOST_0178 72425a27e5240d2790f608322ab35006 205 Gene3D G3DSA:1.10.530.10 61 204 1.1E-42 T 13-10-2018 CLOST_0178 72425a27e5240d2790f608322ab35006 205 PRINTS PR01002 Flagellar protein FlgJ signature 161 180 4.4E-8 T 13-10-2018 CLOST_0178 72425a27e5240d2790f608322ab35006 205 PRINTS PR01002 Flagellar protein FlgJ signature 80 98 4.4E-8 T 13-10-2018 CLOST_0178 72425a27e5240d2790f608322ab35006 205 PRINTS PR01002 Flagellar protein FlgJ signature 181 199 4.4E-8 T 13-10-2018 CLOST_0178 72425a27e5240d2790f608322ab35006 205 SMART SM00047 53 204 3.3E-28 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CLOST_0178 72425a27e5240d2790f608322ab35006 205 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 67 200 2.5E-23 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CLOST_0178 72425a27e5240d2790f608322ab35006 205 Gene3D G3DSA:4.10.80.30 113 138 1.1E-42 T 13-10-2018 CLOST_0341 90e6932df375431cc30800d5b5baf3e0 362 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 207 8.9E-25 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 CLOST_0341 90e6932df375431cc30800d5b5baf3e0 362 Gene3D G3DSA:3.40.1010.10 2 120 3.9E-9 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 CLOST_0341 90e6932df375431cc30800d5b5baf3e0 362 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 255 328 2.5E-23 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CLOST_0341 90e6932df375431cc30800d5b5baf3e0 362 Gene3D G3DSA:1.10.287.1080 229 352 9.3E-36 T 13-10-2018 CLOST_0341 90e6932df375431cc30800d5b5baf3e0 362 SUPERFAMILY SSF53790 1 257 5.96E-27 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 CLOST_0341 90e6932df375431cc30800d5b5baf3e0 362 SUPERFAMILY SSF101386 232 332 6.98E-23 T 13-10-2018 CLOST_0233 d27051db917d6891020633bec76c9849 161 PIRSF PIRSF031501 1 157 1.6E-36 T 13-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CLOST_0233 d27051db917d6891020633bec76c9849 161 Pfam PF06177 QueT transporter 10 148 9.9E-42 T 13-10-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CLOST_1259 7481224c138a76568aa8a46ab1cf35a5 365 Gene3D G3DSA:3.40.50.1440 4 307 2.0E-68 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CLOST_1259 7481224c138a76568aa8a46ab1cf35a5 365 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 4 153 2.3E-12 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CLOST_1259 7481224c138a76568aa8a46ab1cf35a5 365 SUPERFAMILY SSF52490 3 171 5.36E-19 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CLOST_2454 09c8685ec4a9a2ea436173c5b95ddb42 194 Pfam PF07484 Phage Tail Collar Domain 36 90 1.0E-21 T 13-10-2018 IPR011083 Phage tail collar domain CLOST_2454 09c8685ec4a9a2ea436173c5b95ddb42 194 Pfam PF07484 Phage Tail Collar Domain 120 173 2.7E-20 T 13-10-2018 IPR011083 Phage tail collar domain CLOST_2454 09c8685ec4a9a2ea436173c5b95ddb42 194 Gene3D G3DSA:3.90.1340.10 24 88 1.1E-14 T 13-10-2018 IPR037053 Phage tail collar domain superfamily CLOST_2454 09c8685ec4a9a2ea436173c5b95ddb42 194 Gene3D G3DSA:3.90.1340.10 112 172 8.8E-16 T 13-10-2018 IPR037053 Phage tail collar domain superfamily CLOST_2454 09c8685ec4a9a2ea436173c5b95ddb42 194 SUPERFAMILY SSF88874 114 173 4.32E-20 T 13-10-2018 CLOST_2454 09c8685ec4a9a2ea436173c5b95ddb42 194 SUPERFAMILY SSF88874 30 92 2.49E-23 T 13-10-2018 CLOST_2085 fa59403ede48c1eb552e0136e74e3c51 52 Gene3D G3DSA:3.40.50.300 1 51 1.3E-6 T 13-10-2018 CLOST_2085 fa59403ede48c1eb552e0136e74e3c51 52 SUPERFAMILY SSF52540 1 41 2.44E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 Gene3D G3DSA:1.10.540.10 1 120 1.2E-41 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 Gene3D G3DSA:1.20.140.10 235 379 4.3E-59 T 13-10-2018 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 SUPERFAMILY SSF56645 2 242 9.56E-91 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 3.2E-36 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 3.5E-30 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 PIRSF PIRSF016578 6 379 1.9E-26 T 13-10-2018 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 Gene3D G3DSA:2.40.110.10 121 234 3.4E-46 T 13-10-2018 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 SUPERFAMILY SSF47203 228 379 1.13E-61 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 CLOST_1135 143406d65a1ff844c8e6d43bedaa2a4c 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 377 1.2E-55 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 Pfam PF01189 16S rRNA methyltransferase RsmB/F 99 290 3.3E-45 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 Gene3D G3DSA:2.30.130.60 392 455 1.2E-12 T 13-10-2018 CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 SUPERFAMILY SSF53335 3 292 9.29E-60 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 174 186 1.4E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 107 117 1.4E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 78 92 1.4E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 223 239 1.4E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 275 292 1.4E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 407 454 2.0E-15 T 13-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 4 92 3.0E-30 T 13-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 328 388 6.2E-14 T 13-10-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 Gene3D G3DSA:3.40.50.150 94 391 3.2E-76 T 13-10-2018 CLOST_1193 ed1ab0d1bd54d1cf31218f05dbce7c67 455 Gene3D G3DSA:3.30.70.3130 3 91 7.1E-29 T 13-10-2018 CLOST_1415 57c918b8301757ebcb489de1688c85e1 350 Gene3D G3DSA:3.10.520.20 26 349 2.9E-92 T 13-10-2018 CLOST_1415 57c918b8301757ebcb489de1688c85e1 350 SUPERFAMILY SSF143631 37 346 1.05E-76 T 13-10-2018 IPR003374 ApbE-like superfamily CLOST_1415 57c918b8301757ebcb489de1688c85e1 350 PIRSF PIRSF006268 1 349 3.8E-79 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 CLOST_1415 57c918b8301757ebcb489de1688c85e1 350 Pfam PF02424 ApbE family 41 330 1.4E-64 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 CLOST_1404 ca2453299889336edde1ee44335908f3 284 Pfam PF06081 Aromatic acid exporter family member 1 1 137 2.2E-23 T 13-10-2018 IPR010343 Aromatic acid exporter family member 1 CLOST_2465 835ee3086c37b2ca0f02d8f221c87013 281 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_2465 835ee3086c37b2ca0f02d8f221c87013 281 SMART SM00382 28 217 6.8E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2465 835ee3086c37b2ca0f02d8f221c87013 281 Gene3D G3DSA:3.40.50.300 2 257 1.2E-64 T 13-10-2018 CLOST_2465 835ee3086c37b2ca0f02d8f221c87013 281 SUPERFAMILY SSF52540 4 230 2.4E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2465 835ee3086c37b2ca0f02d8f221c87013 281 Pfam PF00005 ABC transporter 19 167 9.0E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2035 dfe34276253c454c22c9dcc0b8f7d5c4 327 PIRSF PIRSF036979 32 324 1.4E-44 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 CLOST_2035 dfe34276253c454c22c9dcc0b8f7d5c4 327 Hamap MF_00737 Formimidoylglutamase [hutG]. 7 318 39.163 T 13-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CLOST_2035 dfe34276253c454c22c9dcc0b8f7d5c4 327 Pfam PF00491 Arginase family 49 315 2.6E-60 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 CLOST_2035 dfe34276253c454c22c9dcc0b8f7d5c4 327 TIGRFAM TIGR01227 hutG: formimidoylglutamase 12 317 3.7E-83 T 13-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CLOST_2035 dfe34276253c454c22c9dcc0b8f7d5c4 327 SUPERFAMILY SSF52768 11 320 2.52E-80 T 13-10-2018 IPR023696 Ureohydrolase domain superfamily CLOST_2035 dfe34276253c454c22c9dcc0b8f7d5c4 327 Gene3D G3DSA:3.40.800.10 3 325 3.9E-109 T 13-10-2018 CLOST_1137 02b7fae996062f88919d3e4b09488051 336 Gene3D G3DSA:3.40.50.1220 207 336 1.9E-55 T 13-10-2018 CLOST_1137 02b7fae996062f88919d3e4b09488051 336 SUPERFAMILY SSF52402 7 203 5.58E-60 T 13-10-2018 CLOST_1137 02b7fae996062f88919d3e4b09488051 336 Pfam PF01012 Electron transfer flavoprotein domain 9 187 7.4E-51 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CLOST_1137 02b7fae996062f88919d3e4b09488051 336 Gene3D G3DSA:3.40.50.620 5 206 2.0E-83 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1137 02b7fae996062f88919d3e4b09488051 336 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 209 292 8.0E-35 T 13-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CLOST_1137 02b7fae996062f88919d3e4b09488051 336 PIRSF PIRSF000089 5 334 9.4E-120 T 13-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CLOST_1137 02b7fae996062f88919d3e4b09488051 336 SMART SM00893 9 198 5.1E-59 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CLOST_1137 02b7fae996062f88919d3e4b09488051 336 SUPERFAMILY SSF52467 209 329 6.54E-46 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily CLOST_2498 8e9529a48a62f41302dbd974c4ec57e1 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.0E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_2498 8e9529a48a62f41302dbd974c4ec57e1 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.0E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_2498 8e9529a48a62f41302dbd974c4ec57e1 210 Gene3D G3DSA:1.10.357.10 1 204 2.7E-50 T 13-10-2018 CLOST_2498 8e9529a48a62f41302dbd974c4ec57e1 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 9.5E-17 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_2498 8e9529a48a62f41302dbd974c4ec57e1 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CLOST_2498 8e9529a48a62f41302dbd974c4ec57e1 210 SUPERFAMILY SSF46689 5 76 1.08E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_1919 3a8c42ae15164617f26868894cf79a87 172 SUPERFAMILY SSF53271 4 170 4.06E-54 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_1919 3a8c42ae15164617f26868894cf79a87 172 Pfam PF00156 Phosphoribosyl transferase domain 11 156 2.7E-26 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOST_1919 3a8c42ae15164617f26868894cf79a87 172 Gene3D G3DSA:3.40.50.2020 1 172 6.2E-65 T 13-10-2018 CLOST_1919 3a8c42ae15164617f26868894cf79a87 172 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 6 170 1.7E-67 T 13-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CLOST_1595 add27f8caa8dbe9e9fc196a520903456 254 Gene3D G3DSA:3.20.20.70 3 254 9.6E-76 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1595 add27f8caa8dbe9e9fc196a520903456 254 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 22 253 32.293 T 13-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CLOST_1595 add27f8caa8dbe9e9fc196a520903456 254 Pfam PF01487 Type I 3-dehydroquinase 24 249 1.5E-58 T 13-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CLOST_1595 add27f8caa8dbe9e9fc196a520903456 254 SUPERFAMILY SSF51569 8 252 2.93E-69 T 13-10-2018 CLOST_1595 add27f8caa8dbe9e9fc196a520903456 254 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 23 249 1.2E-60 T 13-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 SUPERFAMILY SSF56024 96 335 1.6E-41 T 13-10-2018 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 SMART SM00155 419 446 6.3E-5 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 SMART SM00155 241 268 0.0012 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 Gene3D G3DSA:3.30.870.10 327 504 1.6E-31 T 13-10-2018 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 Pfam PF13396 Phospholipase_D-nuclease N-terminal 47 84 1.4E-10 T 13-10-2018 IPR027379 Cardiolipin synthase N-terminal CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 Pfam PF13091 PLD-like domain 158 269 2.8E-13 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 Pfam PF13091 PLD-like domain 348 470 5.8E-24 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 Gene3D G3DSA:3.30.870.10 142 324 2.8E-41 T 13-10-2018 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 47 506 9.1E-104 T 13-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CLOST_1598 cc713e4ac5d96592ce8ff77852aca1d7 506 SUPERFAMILY SSF56024 325 485 2.92E-41 T 13-10-2018 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 SUPERFAMILY SSF63867 327 391 6.28E-9 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 Gene3D G3DSA:3.90.105.10 20 168 2.3E-120 T 13-10-2018 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 171 308 1.7E-31 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 SMART SM00852 174 312 1.9E-35 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 Gene3D G3DSA:2.40.340.10 323 390 2.3E-120 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 Gene3D G3DSA:3.40.980.10 169 322 2.3E-120 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 SUPERFAMILY SSF63882 1 169 3.14E-48 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 Gene3D G3DSA:2.170.190.11 44 135 2.3E-120 T 13-10-2018 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 Pfam PF03454 MoeA C-terminal region (domain IV) 328 390 3.4E-9 T 13-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 Pfam PF00994 Probable molybdopterin binding domain 174 311 6.6E-27 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 247 281 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 Pfam PF03453 MoeA N-terminal region (domain I and II) 2 161 3.0E-42 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CLOST_0836 e0be2e25846ad40fc491ce443b4c3f6e 399 SUPERFAMILY SSF53218 171 316 9.68E-39 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily CLOST_0681 b9070410c54d2a30e51379f1ad1e8154 389 Gene3D G3DSA:3.40.190.10 7 383 6.0E-52 T 13-10-2018 CLOST_0681 b9070410c54d2a30e51379f1ad1e8154 389 Pfam PF01547 Bacterial extracellular solute-binding protein 26 301 2.7E-22 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein CLOST_0681 b9070410c54d2a30e51379f1ad1e8154 389 SUPERFAMILY SSF53850 25 379 6.21E-46 T 13-10-2018 CLOST_0934 dcd79efe60d45d83442289d329e1b921 45 Pfam PF07478 D-ala D-ala ligase C-terminus 1 30 1.5E-9 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 CLOST_0934 dcd79efe60d45d83442289d329e1b921 45 Gene3D G3DSA:3.30.470.20 1 45 7.2E-15 T 13-10-2018 CLOST_1326 8cfa63b587e0afd47787774e5b808ade 221 Gene3D G3DSA:1.25.10.10 92 220 1.3E-9 T 13-10-2018 IPR011989 Armadillo-like helical CLOST_1326 8cfa63b587e0afd47787774e5b808ade 221 SUPERFAMILY SSF48371 104 211 7.58E-11 T 13-10-2018 IPR016024 Armadillo-type fold CLOST_1326 8cfa63b587e0afd47787774e5b808ade 221 Pfam PF13646 HEAT repeats 128 210 7.6E-9 T 13-10-2018 CLOST_0056 112ba7a07e593acb137e7fac9f290ca0 503 Gene3D G3DSA:1.20.1740.10 3 501 2.2E-12 T 13-10-2018 CLOST_0056 112ba7a07e593acb137e7fac9f290ca0 503 PIRSF PIRSF006060 2 503 1.8E-49 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CLOST_0056 112ba7a07e593acb137e7fac9f290ca0 503 Pfam PF13520 Amino acid permease 9 475 7.9E-28 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 SMART SM00283 402 677 1.0E-54 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 Pfam PF17203 Single cache domain 3 193 293 4.3E-8 T 13-10-2018 IPR033463 Single cache domain 3 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 464 611 9.9E-34 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 SUPERFAMILY SSF103190 187 288 9.81E-14 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 Gene3D G3DSA:1.20.1480.50 280 374 5.1E-7 T 13-10-2018 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 SUPERFAMILY SSF58104 349 677 2.09E-65 T 13-10-2018 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 500 527 3.9E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 423 452 3.9E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 529 558 3.9E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 CLOST_2226 f07a986c16a2b43f71aa2a7000d5ced2 678 Gene3D G3DSA:1.10.287.950 375 677 8.6E-61 T 13-10-2018 CLOST_2185 cf973db6d14f0589c20ee7b0533dbbe8 61 SUPERFAMILY SSF57716 3 61 1.57E-22 T 13-10-2018 CLOST_2185 cf973db6d14f0589c20ee7b0533dbbe8 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 13-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2185 cf973db6d14f0589c20ee7b0533dbbe8 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.876 T 13-10-2018 IPR023053 Ribosomal protein S14, type Z CLOST_2185 cf973db6d14f0589c20ee7b0533dbbe8 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 2.4E-25 T 13-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2185 cf973db6d14f0589c20ee7b0533dbbe8 61 Gene3D G3DSA:4.10.830.10 1 61 9.5E-30 T 13-10-2018 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 SMART SM00919 161 385 2.9E-119 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 Gene3D G3DSA:3.40.50.720 159 392 2.6E-80 T 13-10-2018 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 SUPERFAMILY SSF51735 161 391 1.94E-74 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 SUPERFAMILY SSF53223 10 159 2.09E-56 T 13-10-2018 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 Pfam PF03949 Malic enzyme, NAD binding domain 163 385 8.3E-21 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 PIRSF PIRSF000106 19 392 2.8E-83 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 SMART SM01274 16 149 8.7E-85 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 Gene3D G3DSA:3.40.50.10380 1 158 2.9E-77 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 Pfam PF00390 Malic enzyme, N-terminal domain 19 111 2.0E-23 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CLOST_2399 795dc9ad7aa58f95364bbe97178d9c60 392 Pfam PF00390 Malic enzyme, N-terminal domain 112 149 2.0E-6 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CLOST_2134 e883b15bb8b311bc15de23a959934021 306 Pfam PF07136 Protein of unknown function (DUF1385) 52 296 1.9E-88 T 13-10-2018 IPR010787 Protein of unknown function DUF1385 CLOST_2134 e883b15bb8b311bc15de23a959934021 306 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 52 292 2.0E-49 T 13-10-2018 IPR010787 Protein of unknown function DUF1385 CLOST_0213 801eb819fba450feb40d148f54421d0e 234 Gene3D G3DSA:3.40.50.300 2 227 1.3E-62 T 13-10-2018 CLOST_0213 801eb819fba450feb40d148f54421d0e 234 SMART SM00382 33 216 2.1E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0213 801eb819fba450feb40d148f54421d0e 234 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0213 801eb819fba450feb40d148f54421d0e 234 Pfam PF00005 ABC transporter 24 167 1.1E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0213 801eb819fba450feb40d148f54421d0e 234 SUPERFAMILY SSF52540 5 221 5.44E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0842 6ad511b38098210739342e1fc213fbf3 175 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 9 167 1.1E-47 T 13-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CLOST_0842 6ad511b38098210739342e1fc213fbf3 175 Gene3D G3DSA:1.10.1760.20 5 173 4.8E-56 T 13-10-2018 CLOST_0842 6ad511b38098210739342e1fc213fbf3 175 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 7 166 3.2E-42 T 13-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 PIRSF PIRSF001467 1 163 8.3E-45 T 13-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 92 107 2.4E-20 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 107 119 2.4E-20 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 47 59 2.4E-20 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 120 135 2.4E-20 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 21 36 2.4E-20 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 42 59 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 SUPERFAMILY SSF50891 3 160 3.51E-55 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 Gene3D G3DSA:2.40.100.10 2 167 1.7E-58 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily CLOST_0569 187bfa6451b9ba5bd97e95533a219de2 173 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 160 1.2E-51 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 CLOST_2005 e056b7ff5c13bc0b07008438e254db9d 137 Gene3D G3DSA:3.10.180.10 2 136 7.6E-49 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOST_2005 e056b7ff5c13bc0b07008438e254db9d 137 SUPERFAMILY SSF54593 9 132 2.95E-20 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOST_2005 e056b7ff5c13bc0b07008438e254db9d 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 126 3.9E-5 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CLOST_1338 8d5e073404db090ae084d6bf5fbb7f58 286 Pfam PF11382 Copper transport outer membrane protein, MctB 3 283 7.6E-36 T 13-10-2018 IPR021522 Copper transporter MctB GO:0016020|GO:0055070 CLOST_0450 9b6791166dd3ba96696e74f9976945dd 407 Pfam PF00877 NlpC/P60 family 309 396 2.3E-28 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain CLOST_0450 9b6791166dd3ba96696e74f9976945dd 407 Pfam PF07501 G5 domain 229 294 3.9E-15 T 13-10-2018 IPR011098 G5 domain CLOST_0450 9b6791166dd3ba96696e74f9976945dd 407 Gene3D G3DSA:2.20.230.10 217 295 6.4E-13 T 13-10-2018 CLOST_0450 9b6791166dd3ba96696e74f9976945dd 407 SMART SM01208 217 295 1.9E-15 T 13-10-2018 IPR011098 G5 domain CLOST_0450 9b6791166dd3ba96696e74f9976945dd 407 SUPERFAMILY SSF54001 293 406 2.84E-43 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_0450 9b6791166dd3ba96696e74f9976945dd 407 Gene3D G3DSA:3.90.1720.10 296 407 9.0E-43 T 13-10-2018 CLOST_1662 032061bd748d6c612ea07845ceb50b12 162 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 64 77 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CLOST_1662 032061bd748d6c612ea07845ceb50b12 162 SUPERFAMILY SSF53218 2 151 1.96E-45 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily CLOST_1662 032061bd748d6c612ea07845ceb50b12 162 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 4 142 3.0E-35 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_1662 032061bd748d6c612ea07845ceb50b12 162 Pfam PF00994 Probable molybdopterin binding domain 5 147 4.4E-37 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_1662 032061bd748d6c612ea07845ceb50b12 162 Gene3D G3DSA:3.40.980.10 1 153 1.1E-55 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily CLOST_1662 032061bd748d6c612ea07845ceb50b12 162 SMART SM00852 5 148 6.5E-27 T 13-10-2018 IPR001453 MoaB/Mog domain CLOST_0501 ec84d9f59d6dd382b32941b8b5acc5f4 498 Pfam PF07556 Protein of unknown function (DUF1538) 18 228 2.3E-59 T 13-10-2018 IPR011435 Protein of unknown function DUF1538 CLOST_0501 ec84d9f59d6dd382b32941b8b5acc5f4 498 Pfam PF07556 Protein of unknown function (DUF1538) 273 482 1.4E-66 T 13-10-2018 IPR011435 Protein of unknown function DUF1538 CLOST_1603 2872f314cf7a52ffb3c220b20e0f4a91 328 PIRSF PIRSF001439 1 328 3.5E-88 T 13-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CLOST_1603 2872f314cf7a52ffb3c220b20e0f4a91 328 Gene3D G3DSA:3.30.1780.10 6 323 9.8E-100 T 13-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CLOST_1603 2872f314cf7a52ffb3c220b20e0f4a91 328 Gene3D G3DSA:3.40.50.720 126 301 9.8E-100 T 13-10-2018 CLOST_1603 2872f314cf7a52ffb3c220b20e0f4a91 328 SUPERFAMILY SSF51735 1 327 4.9E-91 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1603 2872f314cf7a52ffb3c220b20e0f4a91 328 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 5 319 8.1E-76 T 13-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CLOST_0909 58d06a33d387cda05eaa460e101b6e45 159 PIRSF PIRSF000216 2 159 1.2E-50 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0909 58d06a33d387cda05eaa460e101b6e45 159 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 16 157 2.3E-47 T 13-10-2018 CLOST_0909 58d06a33d387cda05eaa460e101b6e45 159 SUPERFAMILY SSF52833 7 158 1.34E-48 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_0909 58d06a33d387cda05eaa460e101b6e45 159 Gene3D G3DSA:1.10.10.1590 4 74 1.1E-12 T 13-10-2018 CLOST_0909 58d06a33d387cda05eaa460e101b6e45 159 Gene3D G3DSA:3.40.30.10 75 157 2.4E-28 T 13-10-2018 CLOST_1935 0b28f8de7268f42f18d6060c0f283cff 222 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 31 215 1.1E-50 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CLOST_1935 0b28f8de7268f42f18d6060c0f283cff 222 Pfam PF02390 Putative methyltransferase 39 212 2.3E-41 T 13-10-2018 CLOST_1935 0b28f8de7268f42f18d6060c0f283cff 222 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 217 26.736 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CLOST_1935 0b28f8de7268f42f18d6060c0f283cff 222 SUPERFAMILY SSF53335 38 213 3.82E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1935 0b28f8de7268f42f18d6060c0f283cff 222 Gene3D G3DSA:3.40.50.150 1 216 2.5E-60 T 13-10-2018 CLOST_2022 591aaeb10fc63935f0a2673c9a6e7960 289 Gene3D G3DSA:3.30.70.20 66 114 6.2E-10 T 13-10-2018 CLOST_2022 591aaeb10fc63935f0a2673c9a6e7960 289 SUPERFAMILY SSF52540 6 270 2.81E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2022 591aaeb10fc63935f0a2673c9a6e7960 289 Pfam PF13187 4Fe-4S dicluster domain 70 114 6.0E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2022 591aaeb10fc63935f0a2673c9a6e7960 289 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 257 4.5E-14 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOST_2022 591aaeb10fc63935f0a2673c9a6e7960 289 SUPERFAMILY SSF54862 49 122 5.65E-18 T 13-10-2018 CLOST_2022 591aaeb10fc63935f0a2673c9a6e7960 289 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0291 96852077648c494727d77f7e17c93681 63 Gene3D G3DSA:3.40.50.300 2 61 1.2E-16 T 13-10-2018 CLOST_0291 96852077648c494727d77f7e17c93681 63 SUPERFAMILY SSF52540 1 54 2.89E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0783 dc728e839d2196beeb6cb3e108219cd6 396 Pfam PF09335 SNARE associated Golgi protein 235 351 5.0E-28 T 13-10-2018 IPR032816 SNARE associated Golgi protein CLOST_1694 e22c3ec728b586bc4eae719fadb4bb22 152 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 3 152 21.975 T 13-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CLOST_1694 e22c3ec728b586bc4eae719fadb4bb22 152 SUPERFAMILY SSF74942 84 151 1.03E-12 T 13-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily CLOST_1694 e22c3ec728b586bc4eae719fadb4bb22 152 Gene3D G3DSA:3.30.300.70 2 80 1.0E-25 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily CLOST_1694 e22c3ec728b586bc4eae719fadb4bb22 152 Pfam PF17384 RimP C-terminal SH3 domain 86 151 3.8E-8 T 13-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CLOST_1694 e22c3ec728b586bc4eae719fadb4bb22 152 Gene3D G3DSA:2.30.30.180 87 150 7.4E-8 T 13-10-2018 CLOST_1694 e22c3ec728b586bc4eae719fadb4bb22 152 Pfam PF02576 RimP N-terminal domain 20 83 2.5E-24 T 13-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CLOST_1694 e22c3ec728b586bc4eae719fadb4bb22 152 SUPERFAMILY SSF75420 3 83 1.83E-23 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily CLOST_1038 c1cd79197b48ad51f8d53e2e588ef255 688 Gene3D G3DSA:3.30.230.10 506 685 7.5E-16 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_1038 c1cd79197b48ad51f8d53e2e588ef255 688 SUPERFAMILY SSF54211 508 687 6.83E-22 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_1038 c1cd79197b48ad51f8d53e2e588ef255 688 TIGRFAM TIGR02688 TIGR02688: TIGR02688 family protein 21 469 1.2E-185 T 13-10-2018 IPR014061 Conserved hypothetical protein CHP02688 CLOST_1038 c1cd79197b48ad51f8d53e2e588ef255 688 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 525 684 4.7E-7 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CLOST_1038 c1cd79197b48ad51f8d53e2e588ef255 688 Pfam PF13337 Putative ATP-dependent Lon protease 23 478 2.0E-205 T 13-10-2018 IPR014061 Conserved hypothetical protein CHP02688 CLOST_1038 c1cd79197b48ad51f8d53e2e588ef255 688 TIGRFAM TIGR02653 Lon_rel_chp: conserved hypothetical protein 15 687 0.0 T 13-10-2018 IPR013473 Conserved hypothetical protein CHP02653, peptidase S16 non-peptidase homologue CLOST_2129 c5ca899ebc8ad89967231b55a02f1708 151 SUPERFAMILY SSF89623 1 144 1.12E-60 T 13-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CLOST_2129 c5ca899ebc8ad89967231b55a02f1708 151 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 4 144 3.8E-59 T 13-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CLOST_2129 c5ca899ebc8ad89967231b55a02f1708 151 PIRSF PIRSF005384 1 146 1.3E-61 T 13-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CLOST_2129 c5ca899ebc8ad89967231b55a02f1708 151 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 144 1.7E-56 T 13-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 CLOST_2129 c5ca899ebc8ad89967231b55a02f1708 151 Pfam PF02502 Ribose/Galactose Isomerase 3 140 1.2E-58 T 13-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CLOST_2129 c5ca899ebc8ad89967231b55a02f1708 151 Gene3D G3DSA:3.40.1400.10 1 146 1.3E-60 T 13-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CLOST_1527 754047b28cd6359beef23c8d69e9b30c 347 Pfam PF05065 Phage capsid family 78 315 1.1E-7 T 13-10-2018 IPR024455 Phage capsid CLOST_1527 754047b28cd6359beef23c8d69e9b30c 347 SUPERFAMILY SSF56563 71 322 9.29E-18 T 13-10-2018 CLOST_1527 754047b28cd6359beef23c8d69e9b30c 347 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 55 243 3.5E-9 T 13-10-2018 IPR024455 Phage capsid CLOST_0147 0ede84fff1adf9fd44e64401f05fd7e9 340 Gene3D G3DSA:1.10.3210.10 184 288 1.7E-16 T 13-10-2018 CLOST_0147 0ede84fff1adf9fd44e64401f05fd7e9 340 SUPERFAMILY SSF109604 139 282 1.08E-7 T 13-10-2018 CLOST_0147 0ede84fff1adf9fd44e64401f05fd7e9 340 Pfam PF13487 HD domain 202 234 8.5E-7 T 13-10-2018 CLOST_0147 0ede84fff1adf9fd44e64401f05fd7e9 340 Gene3D G3DSA:1.10.3210.10 1 180 2.1E-12 T 13-10-2018 CLOST_2473 810cf11d42f43ba7b333ff190a0669f7 536 SUPERFAMILY SSF51338 4 531 1.16E-15 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_2473 810cf11d42f43ba7b333ff190a0669f7 536 SUPERFAMILY SSF51556 55 490 3.24E-30 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_2473 810cf11d42f43ba7b333ff190a0669f7 536 Gene3D G3DSA:2.30.40.10 6 507 3.7E-127 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_2473 810cf11d42f43ba7b333ff190a0669f7 536 Gene3D G3DSA:3.20.20.140 56 489 3.7E-127 T 13-10-2018 CLOST_2473 810cf11d42f43ba7b333ff190a0669f7 536 Gene3D G3DSA:3.10.310.70 74 194 3.7E-127 T 13-10-2018 CLOST_2473 810cf11d42f43ba7b333ff190a0669f7 536 Pfam PF07969 Amidohydrolase family 44 530 1.1E-90 T 13-10-2018 IPR013108 Amidohydrolase 3 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 Pfam PF00365 Phosphofructokinase 3 275 9.4E-111 T 13-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 2.3E-126 T 13-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 5.1E-83 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 Gene3D G3DSA:3.40.50.450 3 286 3.8E-113 T 13-10-2018 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 PIRSF PIRSF000532 1 319 6.0E-120 T 13-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 13-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 Gene3D G3DSA:3.40.50.460 142 251 3.8E-113 T 13-10-2018 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 45.968 T 13-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CLOST_1648 2eddf53846557c185280f9ca7d5c6cef 319 SUPERFAMILY SSF53784 1 314 2.88E-118 T 13-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 SMART SM00450 201 324 3.3E-9 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 SMART SM00450 53 173 1.7E-14 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 SUPERFAMILY SSF52821 209 327 3.54E-25 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 Gene3D G3DSA:3.40.250.10 47 184 1.5E-34 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 ProSitePatterns PS00380 Rhodanese signature 1. 88 99 - T 13-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 Pfam PF00581 Rhodanese-like domain 55 169 3.3E-15 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 Pfam PF00581 Rhodanese-like domain 203 320 3.0E-11 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 Gene3D G3DSA:3.40.250.10 190 337 8.4E-35 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_2425 ace927ef6d3a65e40e23217ea39ecd13 339 SUPERFAMILY SSF52821 50 184 3.01E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1008 67d5014a97c235a795b7b27b8ad16907 141 SUPERFAMILY SSF52402 1 140 8.04E-31 T 13-10-2018 CLOST_1008 67d5014a97c235a795b7b27b8ad16907 141 Pfam PF00582 Universal stress protein family 1 140 1.7E-22 T 13-10-2018 IPR006016 UspA CLOST_1008 67d5014a97c235a795b7b27b8ad16907 141 PRINTS PR01438 Universal stress protein signature 101 113 1.0E-12 T 13-10-2018 IPR006015 Universal stress protein A CLOST_1008 67d5014a97c235a795b7b27b8ad16907 141 PRINTS PR01438 Universal stress protein signature 119 141 1.0E-12 T 13-10-2018 IPR006015 Universal stress protein A CLOST_1008 67d5014a97c235a795b7b27b8ad16907 141 PRINTS PR01438 Universal stress protein signature 1 16 1.0E-12 T 13-10-2018 IPR006015 Universal stress protein A CLOST_1008 67d5014a97c235a795b7b27b8ad16907 141 Gene3D G3DSA:3.40.50.620 1 141 1.9E-31 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0044 01c978e2342c04f85d9617571f869fb5 491 Gene3D G3DSA:3.90.100.10 392 484 1.3E-16 T 13-10-2018 CLOST_0044 01c978e2342c04f85d9617571f869fb5 491 SUPERFAMILY SSF53383 9 383 1.97E-90 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0044 01c978e2342c04f85d9617571f869fb5 491 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 9 371 8.6E-85 T 13-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CLOST_0044 01c978e2342c04f85d9617571f869fb5 491 Gene3D G3DSA:3.40.640.10 8 284 7.5E-96 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0044 01c978e2342c04f85d9617571f869fb5 491 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 222 236 - T 13-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CLOST_0044 01c978e2342c04f85d9617571f869fb5 491 SUPERFAMILY SSF55904 342 484 1.44E-33 T 13-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 CLOST_0044 01c978e2342c04f85d9617571f869fb5 491 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 401 463 1.2E-9 T 13-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CLOST_0267 e893fbc16607db899246ca102e71c378 71 Gene3D G3DSA:2.30.30.90 1 71 3.3E-15 T 13-10-2018 IPR038157 Ferrous iron transporter, core domain CLOST_0267 e893fbc16607db899246ca102e71c378 71 SMART SM00899 1 71 4.3E-9 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOST_0267 e893fbc16607db899246ca102e71c378 71 Pfam PF04023 FeoA domain 1 70 9.6E-16 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOST_0267 e893fbc16607db899246ca102e71c378 71 SUPERFAMILY SSF50037 3 70 1.28E-11 T 13-10-2018 IPR008988 Transcriptional repressor, C-terminal CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 25.144 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 5.1E-35 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 SUPERFAMILY SSF50249 7 84 1.97E-30 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 13-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 6 78 7.0E-26 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.8E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.8E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.8E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 Pfam PF00366 Ribosomal protein S17 12 79 5.0E-31 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2189 9b754469e87841e69bc2c5778bff3bad 86 Gene3D G3DSA:2.40.50.140 6 85 1.3E-34 T 13-10-2018 CLOST_2133 1e46866690ea2f78ce451d0494b35a49 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 186 192 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOST_2133 1e46866690ea2f78ce451d0494b35a49 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 282 39.829 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CLOST_2133 1e46866690ea2f78ce451d0494b35a49 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 24 278 3.6E-85 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CLOST_2133 1e46866690ea2f78ce451d0494b35a49 283 SUPERFAMILY SSF53335 3 279 1.32E-52 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_2133 1e46866690ea2f78ce451d0494b35a49 283 Pfam PF05175 Methyltransferase small domain 106 197 8.7E-14 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 CLOST_2133 1e46866690ea2f78ce451d0494b35a49 283 Gene3D G3DSA:1.10.8.10 1 83 1.1E-17 T 13-10-2018 CLOST_2133 1e46866690ea2f78ce451d0494b35a49 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 4 281 3.1E-73 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CLOST_2133 1e46866690ea2f78ce451d0494b35a49 283 Gene3D G3DSA:3.40.50.150 84 281 6.6E-63 T 13-10-2018 CLOST_1620 0c69a2c8c54ec9c6171d0e6494c5f080 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 240 249 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 CLOST_1620 0c69a2c8c54ec9c6171d0e6494c5f080 395 Gene3D G3DSA:3.90.1150.10 39 386 8.8E-146 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1620 0c69a2c8c54ec9c6171d0e6494c5f080 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 395 3.0E-182 T 13-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type CLOST_1620 0c69a2c8c54ec9c6171d0e6494c5f080 395 SUPERFAMILY SSF53383 9 393 7.01E-115 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1620 0c69a2c8c54ec9c6171d0e6494c5f080 395 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 24 385 1.4E-130 T 13-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CLOST_1620 0c69a2c8c54ec9c6171d0e6494c5f080 395 Pfam PF00155 Aminotransferase class I and II 44 385 3.7E-67 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_1620 0c69a2c8c54ec9c6171d0e6494c5f080 395 Gene3D G3DSA:3.40.640.10 58 293 8.8E-146 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0484 0d0b2f8b6db829a4a644143969726da7 271 SUPERFAMILY SSF143597 41 241 5.1E-68 T 13-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily CLOST_0484 0d0b2f8b6db829a4a644143969726da7 271 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 5 248 2.2E-78 T 13-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CLOST_0484 0d0b2f8b6db829a4a644143969726da7 271 Gene3D G3DSA:3.40.1700.10 103 255 1.4E-60 T 13-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily CLOST_0484 0d0b2f8b6db829a4a644143969726da7 271 Hamap MF_01499 Diadenylate cyclase [dacA]. 6 255 34.379 T 13-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CLOST_0484 0d0b2f8b6db829a4a644143969726da7 271 PIRSF PIRSF004793 7 266 6.1E-91 T 13-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CLOST_0484 0d0b2f8b6db829a4a644143969726da7 271 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 119 237 1.2E-43 T 13-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CLOST_1096 6f38d91467c59a836c3eb6359bbebab0 196 Pfam PF12840 Helix-turn-helix domain 13 68 1.3E-9 T 13-10-2018 CLOST_1096 6f38d91467c59a836c3eb6359bbebab0 196 SMART SM00418 11 109 0.0048 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CLOST_1096 6f38d91467c59a836c3eb6359bbebab0 196 Gene3D G3DSA:1.10.10.10 5 83 3.2E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1096 6f38d91467c59a836c3eb6359bbebab0 196 SUPERFAMILY SSF46785 1 86 1.42E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2427 23e61fe942499dbd3ee74b07a280633d 323 Pfam PF00188 Cysteine-rich secretory protein family 204 319 6.5E-20 T 13-10-2018 IPR014044 CAP domain CLOST_2427 23e61fe942499dbd3ee74b07a280633d 323 Gene3D G3DSA:3.40.33.10 79 320 1.6E-47 T 13-10-2018 IPR035940 CAP superfamily CLOST_2427 23e61fe942499dbd3ee74b07a280633d 323 SUPERFAMILY SSF55797 195 321 4.19E-25 T 13-10-2018 IPR035940 CAP superfamily CLOST_1632 f4b3574ed4528f60ca778587915adfb8 278 Pfam PF01061 ABC-2 type transporter 4 209 3.4E-32 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CLOST_1632 f4b3574ed4528f60ca778587915adfb8 278 PIRSF PIRSF006648 1 261 2.3E-42 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_1632 f4b3574ed4528f60ca778587915adfb8 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 48 70 2.3E-12 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_1632 f4b3574ed4528f60ca778587915adfb8 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 167 186 2.3E-12 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_1632 f4b3574ed4528f60ca778587915adfb8 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 130 154 2.3E-12 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_1632 f4b3574ed4528f60ca778587915adfb8 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 187 206 2.3E-12 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_1777 f18f503588560885de5012cb82d38b58 157 SUPERFAMILY SSF55486 19 156 9.28E-39 T 13-10-2018 CLOST_1777 f18f503588560885de5012cb82d38b58 157 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 157 22.514 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CLOST_1777 f18f503588560885de5012cb82d38b58 157 Gene3D G3DSA:3.40.390.30 2 155 4.4E-41 T 13-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 CLOST_1777 f18f503588560885de5012cb82d38b58 157 Pfam PF02130 Uncharacterized protein family UPF0054 17 152 1.4E-42 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CLOST_1777 f18f503588560885de5012cb82d38b58 157 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 154 9.5E-37 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CLOST_0293 dc0f762c745f213edb151a9a39b7aa5b 449 PIRSF PIRSF006603 1 449 3.6E-63 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0293 dc0f762c745f213edb151a9a39b7aa5b 449 Pfam PF01554 MatE 242 406 5.8E-16 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0293 dc0f762c745f213edb151a9a39b7aa5b 449 Pfam PF01554 MatE 26 183 7.0E-24 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_0293 dc0f762c745f213edb151a9a39b7aa5b 449 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 417 1.1E-51 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 Pfam PF07837 Formiminotransferase domain, N-terminal subdomain 4 179 1.7E-68 T 13-10-2018 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 SMART SM01222 3 180 2.6E-96 T 13-10-2018 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 SUPERFAMILY SSF55116 4 179 8.63E-65 T 13-10-2018 IPR022384 Formiminotransferase catalytic domain superfamily GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 SMART SM01221 181 295 1.6E-57 T 13-10-2018 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 Gene3D G3DSA:3.30.70.670 182 297 8.6E-36 T 13-10-2018 IPR037070 Formiminotransferase, C-terminal subdomain superfamily GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 TIGRFAM TIGR02024 FtcD: glutamate formiminotransferase 2 296 2.7E-123 T 13-10-2018 IPR004227 Formiminotransferase catalytic domain GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 Gene3D G3DSA:3.30.990.10 2 180 2.8E-64 T 13-10-2018 IPR037064 Formiminotransferase, N-terminal subdomain superfamily GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 SUPERFAMILY SSF55116 181 296 4.18E-40 T 13-10-2018 IPR022384 Formiminotransferase catalytic domain superfamily GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030 CLOST_1282 d1b2555541227e86e14f5c14c71d3df0 298 Pfam PF02971 Formiminotransferase domain 182 286 1.5E-24 T 13-10-2018 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CLOST_1800 3ebba81e1e395e31028361d372f687fe 503 Gene3D G3DSA:3.90.700.10 228 338 2.7E-136 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 CLOST_1800 3ebba81e1e395e31028361d372f687fe 503 Pfam PF00890 FAD binding domain 4 372 1.3E-82 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CLOST_1800 3ebba81e1e395e31028361d372f687fe 503 Gene3D G3DSA:3.50.50.60 4 384 2.7E-136 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1800 3ebba81e1e395e31028361d372f687fe 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 335 357 6.4E-6 T 13-10-2018 CLOST_1800 3ebba81e1e395e31028361d372f687fe 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.4E-6 T 13-10-2018 CLOST_1800 3ebba81e1e395e31028361d372f687fe 503 SUPERFAMILY SSF56425 218 332 5.38E-35 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 CLOST_1800 3ebba81e1e395e31028361d372f687fe 503 SUPERFAMILY SSF51905 2 389 3.71E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1115 dce27d4d5bb6e64646a952d116575726 511 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 254 332 2.2E-11 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CLOST_1115 dce27d4d5bb6e64646a952d116575726 511 SUPERFAMILY SSF53901 183 291 1.81E-13 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_1115 dce27d4d5bb6e64646a952d116575726 511 Gene3D G3DSA:3.40.47.10 177 412 2.5E-10 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_1115 dce27d4d5bb6e64646a952d116575726 511 PIRSF PIRSF037559 1 511 1.8E-286 T 13-10-2018 IPR017236 Glycine/sarcosine/betaine reductase, component C, beta CLOST_0755 3a4cd627b7fca051dd076aee87f4be67 393 SUPERFAMILY SSF52518 5 253 2.16E-57 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_0755 3a4cd627b7fca051dd076aee87f4be67 393 Gene3D G3DSA:3.40.50.970 4 254 2.5E-92 T 13-10-2018 CLOST_0755 3a4cd627b7fca051dd076aee87f4be67 393 SUPERFAMILY SSF52922 257 382 1.86E-31 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_0755 3a4cd627b7fca051dd076aee87f4be67 393 Gene3D G3DSA:3.40.50.920 256 393 1.9E-37 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_0755 3a4cd627b7fca051dd076aee87f4be67 393 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 241 6.6E-60 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CLOST_0755 3a4cd627b7fca051dd076aee87f4be67 393 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 367 6.2E-30 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CLOST_1652 281cefde3723763962b7c853571f14bc 327 SMART SM00930 253 327 1.6E-25 T 13-10-2018 IPR018449 NIL domain CLOST_1652 281cefde3723763962b7c853571f14bc 327 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1652 281cefde3723763962b7c853571f14bc 327 SMART SM00382 30 218 7.8E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1652 281cefde3723763962b7c853571f14bc 327 Pfam PF00005 ABC transporter 21 169 4.3E-38 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1652 281cefde3723763962b7c853571f14bc 327 Pfam PF09383 NIL domain 256 326 5.1E-21 T 13-10-2018 IPR018449 NIL domain CLOST_1652 281cefde3723763962b7c853571f14bc 327 Gene3D G3DSA:3.40.50.300 1 230 2.3E-77 T 13-10-2018 CLOST_1652 281cefde3723763962b7c853571f14bc 327 Gene3D G3DSA:3.30.70.260 231 327 6.2E-24 T 13-10-2018 CLOST_1652 281cefde3723763962b7c853571f14bc 327 SUPERFAMILY SSF55021 249 327 1.26E-19 T 13-10-2018 CLOST_1652 281cefde3723763962b7c853571f14bc 327 SUPERFAMILY SSF52540 1 234 1.87E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 ProSitePatterns PS00321 recA signature. 217 225 - T 13-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 8 328 6.2E-176 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 Gene3D G3DSA:3.40.50.300 30 271 1.6E-80 T 13-10-2018 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 SUPERFAMILY SSF54752 272 329 5.23E-22 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 PRINTS PR00142 RecA protein signature 131 160 1.8E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 PRINTS PR00142 RecA protein signature 97 126 1.8E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 PRINTS PR00142 RecA protein signature 169 198 1.8E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 PRINTS PR00142 RecA protein signature 301 318 1.8E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 PRINTS PR00142 RecA protein signature 214 242 1.8E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 PRINTS PR00142 RecA protein signature 247 276 1.8E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 Pfam PF00154 recA bacterial DNA recombination protein 11 272 5.2E-144 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 Hamap MF_00268 Protein RecA [recA]. 9 333 53.561 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 Gene3D G3DSA:3.30.250.10 272 330 2.0E-26 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 SUPERFAMILY SSF52540 8 271 6.25E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1679 870d36e87a7d68ad0761fe366cb8e129 350 SMART SM00382 61 232 1.2E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1983 49af72593c4f2418ffa95ad02b9e91b7 304 Gene3D G3DSA:3.40.1790.10 1 304 6.0E-140 T 13-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CLOST_1983 49af72593c4f2418ffa95ad02b9e91b7 304 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 9 302 43.804 T 13-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CLOST_1983 49af72593c4f2418ffa95ad02b9e91b7 304 SUPERFAMILY SSF110581 2 301 5.49E-118 T 13-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CLOST_1983 49af72593c4f2418ffa95ad02b9e91b7 304 Pfam PF04227 Indigoidine synthase A like protein 10 299 3.3E-135 T 13-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CLOST_0131 8f69a875f564e6cc603d98523d438eed 97 Gene3D G3DSA:3.30.565.10 1 97 1.2E-23 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0131 8f69a875f564e6cc603d98523d438eed 97 SUPERFAMILY SSF55874 2 96 1.1E-20 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0131 8f69a875f564e6cc603d98523d438eed 97 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2 96 1.7E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0131 8f69a875f564e6cc603d98523d438eed 97 PRINTS PR00344 Bacterial sensor protein C-terminal signature 27 41 3.7E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0131 8f69a875f564e6cc603d98523d438eed 97 PRINTS PR00344 Bacterial sensor protein C-terminal signature 45 55 3.7E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0131 8f69a875f564e6cc603d98523d438eed 97 PRINTS PR00344 Bacterial sensor protein C-terminal signature 58 76 3.7E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0131 8f69a875f564e6cc603d98523d438eed 97 PRINTS PR00344 Bacterial sensor protein C-terminal signature 83 96 3.7E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CLOST_0513 1d91a11a3b900a3749fabb9c20dc26ca 205 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 2.6E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_0513 1d91a11a3b900a3749fabb9c20dc26ca 205 Pfam PF02080 TrkA-C domain 134 203 1.8E-16 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CLOST_0513 1d91a11a3b900a3749fabb9c20dc26ca 205 Gene3D G3DSA:1.10.10.10 6 124 1.1E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0513 1d91a11a3b900a3749fabb9c20dc26ca 205 SUPERFAMILY SSF46785 6 81 2.96E-12 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0513 1d91a11a3b900a3749fabb9c20dc26ca 205 Gene3D G3DSA:3.30.70.1450 131 205 9.7E-18 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CLOST_0513 1d91a11a3b900a3749fabb9c20dc26ca 205 SUPERFAMILY SSF116726 117 203 6.67E-19 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CLOST_0513 1d91a11a3b900a3749fabb9c20dc26ca 205 SMART SM00345 12 71 5.2E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CLOST_2059 a92c04422dc4d82e3f1f7e9f6bc527a4 448 Gene3D G3DSA:3.30.460.10 8 119 5.7E-8 T 13-10-2018 CLOST_2059 a92c04422dc4d82e3f1f7e9f6bc527a4 448 SMART SM00954 49 185 1.1E-4 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 CLOST_2059 a92c04422dc4d82e3f1f7e9f6bc527a4 448 SUPERFAMILY SSF81301 13 218 1.34E-23 T 13-10-2018 CLOST_2059 a92c04422dc4d82e3f1f7e9f6bc527a4 448 Pfam PF04607 Region found in RelA / SpoT proteins 49 182 4.4E-16 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 CLOST_0746 986b1fe44b7a36bb39db249ca86364ba 407 Gene3D G3DSA:3.60.21.10 1 291 1.2E-67 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like CLOST_0746 986b1fe44b7a36bb39db249ca86364ba 407 Pfam PF00149 Calcineurin-like phosphoesterase 1 240 3.3E-12 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CLOST_0746 986b1fe44b7a36bb39db249ca86364ba 407 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 265 1.6E-52 T 13-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CLOST_0746 986b1fe44b7a36bb39db249ca86364ba 407 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 291 380 5.0E-6 T 13-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CLOST_0746 986b1fe44b7a36bb39db249ca86364ba 407 SUPERFAMILY SSF56300 1 348 1.2E-53 T 13-10-2018 CLOST_0436 9d6c014f5cf13dcde976f43d348cbcab 180 SUPERFAMILY SSF88659 120 177 2.99E-8 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_0436 9d6c014f5cf13dcde976f43d348cbcab 180 SUPERFAMILY SSF88946 23 97 3.73E-7 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_0436 9d6c014f5cf13dcde976f43d348cbcab 180 Gene3D G3DSA:1.20.140.160 83 178 9.6E-6 T 13-10-2018 CLOST_0092 b861adb5a044f94c6cf37e6120107f6c 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 350 7.5E-45 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CLOST_0092 b861adb5a044f94c6cf37e6120107f6c 355 SUPERFAMILY SSF51726 5 354 1.92E-41 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0092 b861adb5a044f94c6cf37e6120107f6c 355 Gene3D G3DSA:3.20.20.210 1 351 1.0E-60 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0626 db9bbd8b8d9043282758e9d5df7a32df 192 SUPERFAMILY SSF53335 77 178 4.75E-16 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0626 db9bbd8b8d9043282758e9d5df7a32df 192 Gene3D G3DSA:3.40.50.150 13 190 1.4E-17 T 13-10-2018 CLOST_0626 db9bbd8b8d9043282758e9d5df7a32df 192 Pfam PF08241 Methyltransferase domain 66 131 4.6E-12 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CLOST_0039 a45bb877d058586e5812f3eebee0553d 240 SUPERFAMILY SSF161098 45 228 6.02E-38 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0039 a45bb877d058586e5812f3eebee0553d 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 227 8.5E-22 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0039 a45bb877d058586e5812f3eebee0553d 240 Gene3D G3DSA:1.10.3720.10 38 237 6.4E-31 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0811 9e23f504f417d142a34034be247e240a 219 Pfam PF00145 C-5 cytosine-specific DNA methylase 71 216 5.6E-12 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CLOST_0811 9e23f504f417d142a34034be247e240a 219 SUPERFAMILY SSF53335 77 219 7.75E-15 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0811 9e23f504f417d142a34034be247e240a 219 Gene3D G3DSA:3.90.120.10 78 203 2.0E-10 T 13-10-2018 CLOST_0811 9e23f504f417d142a34034be247e240a 219 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 197 215 - T 13-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CLOST_1623 0134452b4041d6a17ff7a4a73b9c0ab9 289 Gene3D G3DSA:3.40.50.2300 1 129 2.1E-28 T 13-10-2018 CLOST_1623 0134452b4041d6a17ff7a4a73b9c0ab9 289 Pfam PF13690 Chemotaxis phosphatase CheX 173 257 1.1E-11 T 13-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain CLOST_1623 0134452b4041d6a17ff7a4a73b9c0ab9 289 Gene3D G3DSA:3.40.1550.10 130 283 1.6E-21 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_1623 0134452b4041d6a17ff7a4a73b9c0ab9 289 SUPERFAMILY SSF103039 131 281 1.06E-17 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_1623 0134452b4041d6a17ff7a4a73b9c0ab9 289 Pfam PF00072 Response regulator receiver domain 7 116 6.6E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1623 0134452b4041d6a17ff7a4a73b9c0ab9 289 SUPERFAMILY SSF52172 1 127 1.71E-29 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1623 0134452b4041d6a17ff7a4a73b9c0ab9 289 SMART SM00448 4 116 7.8E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2010 e91ab838098797420235a27bd23f1e2f 262 Pfam PF08543 Phosphomethylpyrimidine kinase 11 255 5.8E-96 T 13-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CLOST_2010 e91ab838098797420235a27bd23f1e2f 262 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 256 4.6E-103 T 13-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CLOST_2010 e91ab838098797420235a27bd23f1e2f 262 Gene3D G3DSA:3.40.1190.20 1 262 8.6E-103 T 13-10-2018 IPR029056 Ribokinase-like CLOST_2010 e91ab838098797420235a27bd23f1e2f 262 SUPERFAMILY SSF53613 1 259 6.39E-79 T 13-10-2018 IPR029056 Ribokinase-like CLOST_2146 353dd5b7daa240ff4793ce4fb70b991a 277 Pfam PF13177 DNA polymerase III, delta subunit 17 150 2.0E-26 T 13-10-2018 CLOST_2146 353dd5b7daa240ff4793ce4fb70b991a 277 SUPERFAMILY SSF52540 20 168 1.23E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2146 353dd5b7daa240ff4793ce4fb70b991a 277 Gene3D G3DSA:3.40.50.300 14 147 5.7E-30 T 13-10-2018 CLOST_2007 d280eafbaa5d1d30fef770f47cc44612 436 Pfam PF01964 Radical SAM ThiC family 5 422 7.1E-198 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CLOST_2007 d280eafbaa5d1d30fef770f47cc44612 436 Gene3D G3DSA:3.20.20.540 46 363 7.0E-139 T 13-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CLOST_2007 d280eafbaa5d1d30fef770f47cc44612 436 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 5 424 7.1E-181 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CLOST_2007 d280eafbaa5d1d30fef770f47cc44612 436 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 4 427 88.361 T 13-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CLOST_1430 8d2431393227102d1ca48afaf65882e0 408 Gene3D G3DSA:3.30.470.20 180 396 4.3E-28 T 13-10-2018 CLOST_1430 8d2431393227102d1ca48afaf65882e0 408 Pfam PF13535 ATP-grasp domain 134 274 9.0E-12 T 13-10-2018 CLOST_1430 8d2431393227102d1ca48afaf65882e0 408 Gene3D G3DSA:3.30.1490.20 117 179 1.9E-5 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CLOST_1430 8d2431393227102d1ca48afaf65882e0 408 SUPERFAMILY SSF56059 99 304 3.54E-33 T 13-10-2018 CLOST_1430 8d2431393227102d1ca48afaf65882e0 408 Gene3D G3DSA:3.40.50.20 1 114 5.6E-32 T 13-10-2018 CLOST_1697 3fdd90cb5a5414ff4af0e8a9be1489bb 334 Pfam PF13180 PDZ domain 126 184 5.2E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 CLOST_1697 3fdd90cb5a5414ff4af0e8a9be1489bb 334 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 122 333 1.1E-47 T 13-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CLOST_1697 3fdd90cb5a5414ff4af0e8a9be1489bb 334 Pfam PF02163 Peptidase family M50 9 320 3.2E-76 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 CLOST_1697 3fdd90cb5a5414ff4af0e8a9be1489bb 334 SUPERFAMILY SSF50156 80 184 1.01E-15 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 CLOST_1697 3fdd90cb5a5414ff4af0e8a9be1489bb 334 SMART SM00228 109 177 2.5E-4 T 13-10-2018 IPR001478 PDZ domain GO:0005515 CLOST_1697 3fdd90cb5a5414ff4af0e8a9be1489bb 334 Gene3D G3DSA:2.30.42.10 122 202 9.4E-16 T 13-10-2018 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Hamap MF_00463 Ion-translocating oxidoreductase complex subunit B [rsxB]. 4 193 28.349 T 13-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Gene3D G3DSA:3.30.70.20 199 266 1.6E-14 T 13-10-2018 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 SUPERFAMILY SSF54862 41 191 1.55E-15 T 13-10-2018 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Pfam PF04060 Putative Fe-S cluster 44 76 1.2E-12 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 SUPERFAMILY SSF54862 165 324 3.14E-31 T 13-10-2018 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Gene3D G3DSA:3.20.20.20 36 98 8.1E-13 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Gene3D G3DSA:3.30.70.20 293 325 4.3E-9 T 13-10-2018 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Gene3D G3DSA:3.30.70.20 145 192 1.8E-13 T 13-10-2018 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Gene3D G3DSA:3.30.70.20 267 292 2.7E-6 T 13-10-2018 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 307 318 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Pfam PF00037 4Fe-4S binding domain 165 186 5.2E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 2 95 4.7E-24 T 13-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Pfam PF14697 4Fe-4S dicluster domain 270 324 7.9E-11 T 13-10-2018 CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 Pfam PF13187 4Fe-4S dicluster domain 216 260 1.4E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1397 dbcf965dde369dfa993c9c6d70c893bd 325 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 245 256 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0243 5e08e3db3036a16ced060987d137f8c3 143 PIRSF PIRSF036409 1 142 7.5E-45 T 13-10-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CLOST_0243 5e08e3db3036a16ced060987d137f8c3 143 Gene3D G3DSA:3.40.50.300 1 141 6.0E-16 T 13-10-2018 CLOST_0243 5e08e3db3036a16ced060987d137f8c3 143 SUPERFAMILY SSF52540 3 140 6.08E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0243 5e08e3db3036a16ced060987d137f8c3 143 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 2 138 4.6E-43 T 13-10-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CLOST_0243 5e08e3db3036a16ced060987d137f8c3 143 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 2 138 3.3E-42 T 13-10-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 CLOST_2344 1e2e3e0f9e1c75e35d81af80e22fca14 642 Pfam PF00535 Glycosyl transferase family 2 6 93 3.2E-16 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CLOST_2344 1e2e3e0f9e1c75e35d81af80e22fca14 642 Gene3D G3DSA:1.25.40.10 177 365 9.7E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2344 1e2e3e0f9e1c75e35d81af80e22fca14 642 SUPERFAMILY SSF48452 193 308 1.06E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2344 1e2e3e0f9e1c75e35d81af80e22fca14 642 Gene3D G3DSA:3.90.550.10 4 160 5.0E-21 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_2344 1e2e3e0f9e1c75e35d81af80e22fca14 642 SUPERFAMILY SSF53448 2 94 3.66E-19 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0037 2054e80b1f9cf52c5f0fde1cb8556583 206 SUPERFAMILY SSF161098 11 195 1.02E-37 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0037 2054e80b1f9cf52c5f0fde1cb8556583 206 Gene3D G3DSA:1.10.3720.10 9 201 5.9E-31 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0037 2054e80b1f9cf52c5f0fde1cb8556583 206 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 202 5.9E-22 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0037 2054e80b1f9cf52c5f0fde1cb8556583 206 PRINTS PR00173 Glutamate-aspartate symporter signature 175 197 4.7E-5 T 13-10-2018 CLOST_0037 2054e80b1f9cf52c5f0fde1cb8556583 206 PRINTS PR00173 Glutamate-aspartate symporter signature 23 43 4.7E-5 T 13-10-2018 CLOST_0037 2054e80b1f9cf52c5f0fde1cb8556583 206 PRINTS PR00173 Glutamate-aspartate symporter signature 67 87 4.7E-5 T 13-10-2018 CLOST_1155 edd5f627cdde22bfaf73b9b8d7f61569 303 Pfam PF01515 Phosphate acetyl/butaryl transferase 57 294 1.7E-36 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_1155 edd5f627cdde22bfaf73b9b8d7f61569 303 PIRSF PIRSF000428 1 303 5.2E-79 T 13-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_1155 edd5f627cdde22bfaf73b9b8d7f61569 303 Gene3D G3DSA:3.40.718.10 2 301 1.2E-99 T 13-10-2018 CLOST_1155 edd5f627cdde22bfaf73b9b8d7f61569 303 SUPERFAMILY SSF53659 8 299 1.64E-59 T 13-10-2018 CLOST_0376 e199568ae5f12091868925e219e75f0a 506 Pfam PF00005 ABC transporter 277 433 5.3E-15 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0376 e199568ae5f12091868925e219e75f0a 506 Gene3D G3DSA:3.40.50.300 1 244 3.5E-61 T 13-10-2018 CLOST_0376 e199568ae5f12091868925e219e75f0a 506 Gene3D G3DSA:3.40.50.300 256 496 1.7E-37 T 13-10-2018 CLOST_0376 e199568ae5f12091868925e219e75f0a 506 SUPERFAMILY SSF52540 241 491 1.84E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0376 e199568ae5f12091868925e219e75f0a 506 Pfam PF00005 ABC transporter 22 171 2.6E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0376 e199568ae5f12091868925e219e75f0a 506 SMART SM00382 285 482 11.0 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0376 e199568ae5f12091868925e219e75f0a 506 SMART SM00382 30 220 4.6E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0376 e199568ae5f12091868925e219e75f0a 506 SUPERFAMILY SSF52540 5 232 2.72E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0376 e199568ae5f12091868925e219e75f0a 506 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1339 4a150d0c47337e73d09c8aea56d8fab8 373 Gene3D G3DSA:3.40.50.10240 160 243 4.0E-12 T 13-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_1339 4a150d0c47337e73d09c8aea56d8fab8 373 Pfam PF12555 Thiamine pyrophosphokinase C terminal 320 370 5.1E-13 T 13-10-2018 IPR022215 Thiamine pyrophosphokinase C-terminal CLOST_1339 4a150d0c47337e73d09c8aea56d8fab8 373 SUPERFAMILY SSF63999 136 293 6.93E-29 T 13-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CLOST_0788 e33f706eaa021a521e7d9a8b866ed16a 319 Gene3D G3DSA:3.30.457.10 245 318 6.6E-12 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0788 e33f706eaa021a521e7d9a8b866ed16a 319 SUPERFAMILY SSF55383 246 314 3.4E-12 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0788 e33f706eaa021a521e7d9a8b866ed16a 319 Pfam PF07833 Copper amine oxidase N-terminal domain 242 312 1.8E-13 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_1133 8af0f8ae9a75b471062ebcfd722257bc 279 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 183 279 9.1E-36 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 CLOST_1133 8af0f8ae9a75b471062ebcfd722257bc 279 PIRSF PIRSF000105 1 279 4.0E-91 T 13-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CLOST_1133 8af0f8ae9a75b471062ebcfd722257bc 279 SUPERFAMILY SSF51735 2 181 9.88E-58 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1133 8af0f8ae9a75b471062ebcfd722257bc 279 Gene3D G3DSA:1.10.1040.10 186 279 3.2E-35 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CLOST_1133 8af0f8ae9a75b471062ebcfd722257bc 279 Gene3D G3DSA:3.40.50.720 1 185 5.1E-69 T 13-10-2018 CLOST_1133 8af0f8ae9a75b471062ebcfd722257bc 279 SUPERFAMILY SSF48179 182 279 1.11E-31 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CLOST_1133 8af0f8ae9a75b471062ebcfd722257bc 279 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2 180 2.6E-65 T 13-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 CLOST_1940 a3381818faafb926d5803cc8ca4f98ab 393 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 252 363 4.5E-18 T 13-10-2018 IPR000160 GGDEF domain CLOST_1940 a3381818faafb926d5803cc8ca4f98ab 393 Pfam PF00990 Diguanylate cyclase, GGDEF domain 255 365 7.3E-20 T 13-10-2018 IPR000160 GGDEF domain CLOST_1940 a3381818faafb926d5803cc8ca4f98ab 393 SUPERFAMILY SSF55073 259 364 2.9E-19 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_1940 a3381818faafb926d5803cc8ca4f98ab 393 Gene3D G3DSA:3.30.70.270 240 385 1.0E-23 T 13-10-2018 CLOST_1940 a3381818faafb926d5803cc8ca4f98ab 393 SMART SM00267 243 393 1.0E-5 T 13-10-2018 IPR000160 GGDEF domain CLOST_0289 441c59a655c475ed13bd65fca5745f8b 376 Gene3D G3DSA:3.20.20.140 49 172 7.1E-12 T 13-10-2018 CLOST_0289 441c59a655c475ed13bd65fca5745f8b 376 Gene3D G3DSA:3.20.20.140 313 335 7.9E-9 T 13-10-2018 CLOST_0289 441c59a655c475ed13bd65fca5745f8b 376 Gene3D G3DSA:2.30.40.10 2 48 7.1E-12 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0289 441c59a655c475ed13bd65fca5745f8b 376 SUPERFAMILY SSF51556 80 339 1.0E-7 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_0289 441c59a655c475ed13bd65fca5745f8b 376 Gene3D G3DSA:2.30.40.10 336 373 7.9E-9 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0289 441c59a655c475ed13bd65fca5745f8b 376 SUPERFAMILY SSF51338 3 373 9.11E-12 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0289 441c59a655c475ed13bd65fca5745f8b 376 Pfam PF07969 Amidohydrolase family 309 372 3.8E-9 T 13-10-2018 IPR013108 Amidohydrolase 3 CLOST_2479 23fb178d5bcfd13c80c5cbaf8b6d5e64 284 Pfam PF00583 Acetyltransferase (GNAT) family 37 134 2.5E-13 T 13-10-2018 IPR000182 GNAT domain CLOST_2479 23fb178d5bcfd13c80c5cbaf8b6d5e64 284 Gene3D G3DSA:3.40.630.30 17 164 4.4E-21 T 13-10-2018 CLOST_2479 23fb178d5bcfd13c80c5cbaf8b6d5e64 284 SUPERFAMILY SSF55729 27 143 1.46E-21 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2479 23fb178d5bcfd13c80c5cbaf8b6d5e64 284 Pfam PF13673 Acetyltransferase (GNAT) domain 194 278 7.4E-9 T 13-10-2018 IPR000182 GNAT domain CLOST_2479 23fb178d5bcfd13c80c5cbaf8b6d5e64 284 Gene3D G3DSA:3.40.630.30 172 284 2.9E-8 T 13-10-2018 CLOST_2479 23fb178d5bcfd13c80c5cbaf8b6d5e64 284 SUPERFAMILY SSF55729 170 281 1.23E-10 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0256 101b0a9c17fcc2d2d38c18fd624afd4e 375 Pfam PF04346 Ethanolamine utilisation protein, EutH 4 355 7.7E-157 T 13-10-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 CLOST_0256 101b0a9c17fcc2d2d38c18fd624afd4e 375 PIRSF PIRSF019466 2 371 4.7E-149 T 13-10-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 CLOST_0575 9e2ea73a8a0a082377ad089bf2b1dc9e 231 SUPERFAMILY SSF51182 4 230 3.34E-50 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0575 9e2ea73a8a0a082377ad089bf2b1dc9e 231 Pfam PF02678 Pirin 10 119 4.2E-24 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CLOST_0575 9e2ea73a8a0a082377ad089bf2b1dc9e 231 PIRSF PIRSF006232 1 229 3.1E-33 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CLOST_0575 9e2ea73a8a0a082377ad089bf2b1dc9e 231 Gene3D G3DSA:2.60.120.10 8 230 2.7E-66 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0575 9e2ea73a8a0a082377ad089bf2b1dc9e 231 Gene3D G3DSA:2.60.120.10 11 136 2.7E-66 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_1323 a00d5781e9f601869330e37f73be7b8b 249 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 3 246 48.106 T 13-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CLOST_1323 a00d5781e9f601869330e37f73be7b8b 249 Pfam PF02540 NAD synthase 11 240 6.1E-72 T 13-10-2018 IPR022310 NAD/GMP synthase CLOST_1323 a00d5781e9f601869330e37f73be7b8b 249 Gene3D G3DSA:3.40.50.620 3 246 1.6E-75 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1323 a00d5781e9f601869330e37f73be7b8b 249 SUPERFAMILY SSF52402 7 247 5.35E-71 T 13-10-2018 CLOST_1323 a00d5781e9f601869330e37f73be7b8b 249 TIGRFAM TIGR00552 nadE: NAD+ synthetase 11 244 2.4E-76 T 13-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CLOST_0121 8c9b7c3cda6595465b16789549660e91 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 112 5.1E-11 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_0121 8c9b7c3cda6595465b16789549660e91 224 SUPERFAMILY SSF51206 17 141 1.19E-20 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like CLOST_0121 8c9b7c3cda6595465b16789549660e91 224 Pfam PF13545 Crp-like helix-turn-helix domain 146 219 4.8E-14 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_0121 8c9b7c3cda6595465b16789549660e91 224 SMART SM00419 165 212 3.4E-4 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_0121 8c9b7c3cda6595465b16789549660e91 224 SUPERFAMILY SSF46785 144 221 1.05E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_0121 8c9b7c3cda6595465b16789549660e91 224 Gene3D G3DSA:2.60.120.1460 14 221 1.7E-43 T 13-10-2018 CLOST_1918 03cbb71c63bb3ed5d0f717cfe8b7e9c9 210 Pfam PF07314 Protein of unknown function (DUF1461) 7 179 2.8E-39 T 13-10-2018 IPR010178 Integral membrane protein 1906 CLOST_1918 03cbb71c63bb3ed5d0f717cfe8b7e9c9 210 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 6 203 2.3E-26 T 13-10-2018 IPR010178 Integral membrane protein 1906 CLOST_1230 cda8d082fe156c9457754c5575c18bc9 308 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 299 29.986 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CLOST_1230 cda8d082fe156c9457754c5575c18bc9 308 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 290 7.5E-95 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CLOST_1230 cda8d082fe156c9457754c5575c18bc9 308 Pfam PF01715 IPP transferase 39 283 1.1E-78 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CLOST_1230 cda8d082fe156c9457754c5575c18bc9 308 Gene3D G3DSA:1.10.20.140 113 184 1.6E-102 T 13-10-2018 CLOST_1230 cda8d082fe156c9457754c5575c18bc9 308 Gene3D G3DSA:3.40.50.300 10 288 1.6E-102 T 13-10-2018 CLOST_1230 cda8d082fe156c9457754c5575c18bc9 308 SUPERFAMILY SSF52540 6 152 1.52E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1230 cda8d082fe156c9457754c5575c18bc9 308 SUPERFAMILY SSF52540 4 306 1.2E-11 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2228 094744f49f86a4412ed79b701ef67995 335 Gene3D G3DSA:3.10.310.10 146 312 5.7E-134 T 13-10-2018 CLOST_2228 094744f49f86a4412ed79b701ef67995 335 SUPERFAMILY SSF54506 1 333 3.14E-111 T 13-10-2018 CLOST_2228 094744f49f86a4412ed79b701ef67995 335 Pfam PF05544 Proline racemase 10 334 8.7E-127 T 13-10-2018 IPR008794 Proline racemase family CLOST_2228 094744f49f86a4412ed79b701ef67995 335 Gene3D G3DSA:3.10.310.10 7 335 5.7E-134 T 13-10-2018 CLOST_2228 094744f49f86a4412ed79b701ef67995 335 PIRSF PIRSF029792 1 335 3.8E-151 T 13-10-2018 IPR008794 Proline racemase family CLOST_1915 ec8d678e595e1b1b6461e69ec1152b7e 190 PIRSF PIRSF010130 1 190 2.2E-86 T 13-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 CLOST_1915 ec8d678e595e1b1b6461e69ec1152b7e 190 Pfam PF06130 Phosphate propanoyltransferase 113 178 2.4E-17 T 13-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 CLOST_1915 ec8d678e595e1b1b6461e69ec1152b7e 190 Pfam PF06130 Phosphate propanoyltransferase 4 83 1.3E-29 T 13-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 CLOST_1356 f7088a426bb1b2c55cb1fff279563e93 228 Gene3D G3DSA:1.10.10.10 130 228 5.9E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1356 f7088a426bb1b2c55cb1fff279563e93 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 8.4E-28 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1356 f7088a426bb1b2c55cb1fff279563e93 228 SMART SM00448 2 112 1.3E-41 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1356 f7088a426bb1b2c55cb1fff279563e93 228 Pfam PF00072 Response regulator receiver domain 4 113 1.0E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1356 f7088a426bb1b2c55cb1fff279563e93 228 Gene3D G3DSA:3.40.50.2300 1 129 2.4E-37 T 13-10-2018 CLOST_1356 f7088a426bb1b2c55cb1fff279563e93 228 SMART SM00862 147 223 3.8E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_1356 f7088a426bb1b2c55cb1fff279563e93 228 SUPERFAMILY SSF52172 1 176 2.73E-39 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_2497 e3ec1958d51f14133d9d88149338d16a 442 Gene3D G3DSA:1.20.1250.20 15 424 6.9E-37 T 13-10-2018 CLOST_2497 e3ec1958d51f14133d9d88149338d16a 442 SUPERFAMILY SSF103473 15 378 3.4E-41 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_2497 e3ec1958d51f14133d9d88149338d16a 442 Pfam PF07690 Major Facilitator Superfamily 21 367 1.3E-30 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 454 1.2E-116 T 13-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 PRINTS PR00149 Fumarate lyase superfamily signature 282 298 9.7E-11 T 13-10-2018 IPR000362 Fumarate lyase family CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 PRINTS PR00149 Fumarate lyase superfamily signature 145 163 9.7E-11 T 13-10-2018 IPR000362 Fumarate lyase family CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 9.7E-11 T 13-10-2018 IPR000362 Fumarate lyase family CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 Pfam PF00206 Lyase 48 302 1.2E-21 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 Pfam PF10397 Adenylosuccinate lyase C-terminus 372 454 1.6E-16 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 ProSitePatterns PS00163 Fumarate lyases signature. 282 291 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 Gene3D G3DSA:1.20.200.10 14 452 5.1E-158 T 13-10-2018 CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 SMART SM00998 371 455 6.7E-23 T 13-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 Gene3D G3DSA:1.10.275.60 25 236 5.1E-158 T 13-10-2018 CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 SUPERFAMILY SSF48557 10 455 4.4E-93 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 CLOST_1238 f660a662c479d4c9a5eb5a88e6274838 477 Gene3D G3DSA:1.10.40.30 369 443 5.1E-158 T 13-10-2018 CLOST_2532 d1a972209abefc5df9c978f0fa69ab85 509 Gene3D G3DSA:3.40.50.150 13 308 9.3E-24 T 13-10-2018 CLOST_2532 d1a972209abefc5df9c978f0fa69ab85 509 Pfam PF02384 N-6 DNA Methylase 29 196 4.1E-9 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CLOST_2532 d1a972209abefc5df9c978f0fa69ab85 509 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 57 71 1.6E-13 T 13-10-2018 CLOST_2532 d1a972209abefc5df9c978f0fa69ab85 509 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 143 155 1.6E-13 T 13-10-2018 CLOST_2532 d1a972209abefc5df9c978f0fa69ab85 509 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 31 47 1.6E-13 T 13-10-2018 CLOST_2532 d1a972209abefc5df9c978f0fa69ab85 509 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 174 198 1.6E-13 T 13-10-2018 CLOST_2532 d1a972209abefc5df9c978f0fa69ab85 509 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 146 152 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOST_2532 d1a972209abefc5df9c978f0fa69ab85 509 SUPERFAMILY SSF53335 23 252 3.79E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_2319 73dbc42dd429530b543d54d0eb72abb9 140 SUPERFAMILY SSF81333 71 138 1.28E-14 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily CLOST_2319 73dbc42dd429530b543d54d0eb72abb9 140 Gene3D G3DSA:1.20.120.610 3 140 1.4E-12 T 13-10-2018 CLOST_2319 73dbc42dd429530b543d54d0eb72abb9 140 PRINTS PR00124 ATP synthase C subunit signature 112 137 8.3E-6 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2319 73dbc42dd429530b543d54d0eb72abb9 140 PRINTS PR00124 ATP synthase C subunit signature 74 93 8.3E-6 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CLOST_2319 73dbc42dd429530b543d54d0eb72abb9 140 Pfam PF00137 ATP synthase subunit C 77 136 1.7E-15 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CLOST_0590 e7892e75862acccb44aacc56e63326af 194 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 45.078 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CLOST_0590 e7892e75862acccb44aacc56e63326af 194 SUPERFAMILY SSF52096 10 192 4.97E-75 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_0590 e7892e75862acccb44aacc56e63326af 194 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 13-10-2018 IPR033135 ClpP, histidine active site CLOST_0590 e7892e75862acccb44aacc56e63326af 194 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 9.4E-56 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CLOST_0590 e7892e75862acccb44aacc56e63326af 194 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 9.4E-56 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CLOST_0590 e7892e75862acccb44aacc56e63326af 194 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 9.4E-56 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CLOST_0590 e7892e75862acccb44aacc56e63326af 194 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 9.4E-56 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CLOST_0590 e7892e75862acccb44aacc56e63326af 194 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 9.4E-56 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CLOST_0590 e7892e75862acccb44aacc56e63326af 194 Pfam PF00574 Clp protease 13 192 3.4E-90 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CLOST_0590 e7892e75862acccb44aacc56e63326af 194 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 13-10-2018 IPR018215 ClpP, Ser active site CLOST_0590 e7892e75862acccb44aacc56e63326af 194 Gene3D G3DSA:3.90.226.10 1 194 2.3E-85 T 13-10-2018 CLOST_0590 e7892e75862acccb44aacc56e63326af 194 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 2 192 2.8E-106 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CLOST_0363 e4a659e5c29d65765f69da32f38f5a1e 377 TIGRFAM TIGR03573 WbuX: N-acetyl sugar amidotransferase 6 350 4.5E-106 T 13-10-2018 IPR020022 N-acetyl sugar amidotransferase CLOST_0363 e4a659e5c29d65765f69da32f38f5a1e 377 Gene3D G3DSA:3.40.50.620 7 194 1.9E-7 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_0363 e4a659e5c29d65765f69da32f38f5a1e 377 SUPERFAMILY SSF52402 20 176 1.04E-13 T 13-10-2018 CLOST_1807 24f4e20c552d01e9657a36f01f306d8b 167 Gene3D G3DSA:1.10.1760.20 1 162 3.1E-45 T 13-10-2018 CLOST_1807 24f4e20c552d01e9657a36f01f306d8b 167 Pfam PF07155 ECF-type riboflavin transporter, S component 2 158 1.2E-39 T 13-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CLOST_1660 cc11aef67473fca3aa816f96c5f8598f 143 Pfam PF03473 MOSC domain 36 115 3.9E-5 T 13-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CLOST_1660 cc11aef67473fca3aa816f96c5f8598f 143 Gene3D G3DSA:2.40.33.20 1 143 9.9E-31 T 13-10-2018 CLOST_1660 cc11aef67473fca3aa816f96c5f8598f 143 SUPERFAMILY SSF50800 1 143 1.94E-36 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily CLOST_0566 0f0233ab4fc64b23431c4c627990e539 504 Pfam PF15975 Flotillin 371 441 3.2E-9 T 13-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CLOST_0566 0f0233ab4fc64b23431c4c627990e539 504 SMART SM00244 25 192 0.0027 T 13-10-2018 IPR001107 Band 7 domain CLOST_0566 0f0233ab4fc64b23431c4c627990e539 504 Pfam PF01145 SPFH domain / Band 7 family 32 208 9.0E-22 T 13-10-2018 IPR001107 Band 7 domain CLOST_0566 0f0233ab4fc64b23431c4c627990e539 504 Gene3D G3DSA:3.30.479.30 65 182 2.7E-35 T 13-10-2018 CLOST_0566 0f0233ab4fc64b23431c4c627990e539 504 SUPERFAMILY SSF117892 56 196 1.16E-29 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily CLOST_2120 44d5ecb715e4b54ddb93a5ceb4084863 169 SUPERFAMILY SSF81573 70 127 2.62E-10 T 13-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily CLOST_2120 44d5ecb715e4b54ddb93a5ceb4084863 169 Hamap MF_01398 ATP synthase subunit b [atpF]. 5 144 12.659 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CLOST_2120 44d5ecb715e4b54ddb93a5ceb4084863 169 Gene3D G3DSA:1.20.5.620 68 127 1.7E-6 T 13-10-2018 CLOST_2120 44d5ecb715e4b54ddb93a5ceb4084863 169 Pfam PF00430 ATP synthase B/B' CF(0) 19 143 3.4E-27 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CLOST_2120 44d5ecb715e4b54ddb93a5ceb4084863 169 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 20 162 2.9E-30 T 13-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CLOST_1419 c50b4efe2f903ec13b1c71cf41002719 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.2E-9 T 13-10-2018 CLOST_1419 c50b4efe2f903ec13b1c71cf41002719 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 9.2E-9 T 13-10-2018 CLOST_1419 c50b4efe2f903ec13b1c71cf41002719 671 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 9.2E-9 T 13-10-2018 CLOST_1419 c50b4efe2f903ec13b1c71cf41002719 671 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 313 5.1E-41 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_1419 c50b4efe2f903ec13b1c71cf41002719 671 SUPERFAMILY SSF51905 2 180 1.13E-25 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1419 c50b4efe2f903ec13b1c71cf41002719 671 Gene3D G3DSA:3.50.50.100 1 415 8.2E-108 T 13-10-2018 CLOST_1419 c50b4efe2f903ec13b1c71cf41002719 671 SUPERFAMILY SSF51905 157 339 1.07E-14 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_2083 c01eb00548dfbf37bf78a0f99f0fd60e 373 Pfam PF01551 Peptidase family M23 273 367 1.3E-35 T 13-10-2018 IPR016047 Peptidase M23 CLOST_2083 c01eb00548dfbf37bf78a0f99f0fd60e 373 SUPERFAMILY SSF51261 218 371 6.02E-60 T 13-10-2018 IPR011055 Duplicated hybrid motif CLOST_2083 c01eb00548dfbf37bf78a0f99f0fd60e 373 Gene3D G3DSA:2.70.70.10 208 372 2.3E-54 T 13-10-2018 IPR011055 Duplicated hybrid motif CLOST_0950 1b9cdb14d109621ba5c723afecd9d111 322 Gene3D G3DSA:1.10.1200.80 254 322 2.7E-15 T 13-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CLOST_0950 1b9cdb14d109621ba5c723afecd9d111 322 Gene3D G3DSA:3.20.20.70 8 247 3.2E-86 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0950 1b9cdb14d109621ba5c723afecd9d111 322 PIRSF PIRSF006621 1 322 1.1E-109 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOST_0950 1b9cdb14d109621ba5c723afecd9d111 322 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 95 113 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOST_0950 1b9cdb14d109621ba5c723afecd9d111 322 SUPERFAMILY SSF51395 12 319 1.03E-89 T 13-10-2018 CLOST_0950 1b9cdb14d109621ba5c723afecd9d111 322 Pfam PF01207 Dihydrouridine synthase (Dus) 14 316 1.4E-99 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CLOST_0950 1b9cdb14d109621ba5c723afecd9d111 322 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 320 7.4E-116 T 13-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CLOST_0516 23dbcf17611995a4aa24bfee4fae2f98 244 SMART SM00850 142 235 0.0021 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CLOST_0516 23dbcf17611995a4aa24bfee4fae2f98 244 Pfam PF04397 LytTr DNA-binding domain 147 232 3.0E-7 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CLOST_0516 23dbcf17611995a4aa24bfee4fae2f98 244 SUPERFAMILY SSF52172 36 114 7.83E-14 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_0516 23dbcf17611995a4aa24bfee4fae2f98 244 Gene3D G3DSA:3.40.50.2300 1 131 8.4E-18 T 13-10-2018 CLOST_0516 23dbcf17611995a4aa24bfee4fae2f98 244 SMART SM00448 1 122 1.1E-5 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_0516 23dbcf17611995a4aa24bfee4fae2f98 244 Gene3D G3DSA:2.40.50.1020 132 230 1.5E-10 T 13-10-2018 CLOST_0516 23dbcf17611995a4aa24bfee4fae2f98 244 Pfam PF00072 Response regulator receiver domain 36 113 9.7E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2402 79aaf70bb19b1af5c882375cf06e50d3 154 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 15 152 1.1E-23 T 13-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CLOST_2402 79aaf70bb19b1af5c882375cf06e50d3 154 SUPERFAMILY SSF50475 1 153 1.75E-52 T 13-10-2018 CLOST_2402 79aaf70bb19b1af5c882375cf06e50d3 154 Gene3D G3DSA:2.30.110.10 4 153 2.0E-44 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 CLOST_2040 74632f0592035473090ee582828e4f56 522 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 474 521 3.2E-9 T 13-10-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 CLOST_2040 74632f0592035473090ee582828e4f56 522 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 234 247 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CLOST_2040 74632f0592035473090ee582828e4f56 522 SUPERFAMILY SSF46689 472 521 4.78E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_2040 74632f0592035473090ee582828e4f56 522 Gene3D G3DSA:3.30.70.260 6 84 3.0E-13 T 13-10-2018 CLOST_2040 74632f0592035473090ee582828e4f56 522 SMART SM00091 84 151 5.1E-5 T 13-10-2018 IPR000014 PAS domain CLOST_2040 74632f0592035473090ee582828e4f56 522 Gene3D G3DSA:3.30.450.20 94 198 1.1E-16 T 13-10-2018 CLOST_2040 74632f0592035473090ee582828e4f56 522 Gene3D G3DSA:3.40.50.300 199 381 5.5E-67 T 13-10-2018 CLOST_2040 74632f0592035473090ee582828e4f56 522 SMART SM00382 230 374 4.6E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2040 74632f0592035473090ee582828e4f56 522 Gene3D G3DSA:1.10.10.60 468 521 1.6E-10 T 13-10-2018 CLOST_2040 74632f0592035473090ee582828e4f56 522 SUPERFAMILY SSF55785 79 185 1.74E-11 T 13-10-2018 IPR035965 PAS domain superfamily CLOST_2040 74632f0592035473090ee582828e4f56 522 Gene3D G3DSA:1.10.8.60 382 448 2.7E-22 T 13-10-2018 CLOST_2040 74632f0592035473090ee582828e4f56 522 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 297 312 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CLOST_2040 74632f0592035473090ee582828e4f56 522 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 81 189 1.4E-5 T 13-10-2018 IPR000014 PAS domain CLOST_2040 74632f0592035473090ee582828e4f56 522 SUPERFAMILY SSF52540 209 452 1.2E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2040 74632f0592035473090ee582828e4f56 522 Pfam PF00158 Sigma-54 interaction domain 210 377 1.5E-70 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CLOST_2040 74632f0592035473090ee582828e4f56 522 Pfam PF13426 PAS domain 95 188 1.3E-7 T 13-10-2018 IPR000014 PAS domain CLOST_2283 446856b934128441002e311b50f39eb2 568 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 511 525 2.4E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2283 446856b934128441002e311b50f39eb2 568 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 525 541 2.4E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2283 446856b934128441002e311b50f39eb2 568 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 541 553 2.4E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2283 446856b934128441002e311b50f39eb2 568 Gene3D G3DSA:1.10.10.10 508 565 3.9E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2283 446856b934128441002e311b50f39eb2 568 Pfam PF00196 Bacterial regulatory proteins, luxR family 511 562 9.0E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2283 446856b934128441002e311b50f39eb2 568 SUPERFAMILY SSF46894 507 563 5.1E-16 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_2283 446856b934128441002e311b50f39eb2 568 ProSitePatterns PS00622 LuxR-type HTH domain signature. 525 552 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_2283 446856b934128441002e311b50f39eb2 568 SMART SM00421 508 565 1.9E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CLOST_0708 945075e4e815cec83ba8841a88cf125c 85 Pfam PF17253 Family of unknown function (DUF5320) 1 85 1.4E-19 T 13-10-2018 IPR035205 Protein of unknown function DUF5320 CLOST_1132 959161196069dd26cd34f31e19c941cf 257 Gene3D G3DSA:3.90.226.10 2 201 4.6E-72 T 13-10-2018 CLOST_1132 959161196069dd26cd34f31e19c941cf 257 SUPERFAMILY SSF52096 4 257 1.06E-90 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CLOST_1132 959161196069dd26cd34f31e19c941cf 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 257 4.8E-72 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 CLOST_1132 959161196069dd26cd34f31e19c941cf 257 Gene3D G3DSA:1.10.12.10 202 257 8.2E-24 T 13-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal CLOST_1132 959161196069dd26cd34f31e19c941cf 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 13-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 CLOST_1730 9870e8aa5b4f0431ef80a3148be43bb7 43 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 36 3.3E-10 T 13-10-2018 IPR025713 Motility protein B, N-terminal domain CLOST_2578 7bc2600e6719a56a2c1de1a6acbd0912 380 Gene3D G3DSA:3.90.1150.10 2 370 4.0E-125 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_2578 7bc2600e6719a56a2c1de1a6acbd0912 380 Gene3D G3DSA:3.40.640.10 16 266 4.0E-125 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_2578 7bc2600e6719a56a2c1de1a6acbd0912 380 TIGRFAM TIGR01977 am_tr_V_EF2568: cysteine desulfurase family protein 2 376 1.1E-147 T 13-10-2018 IPR010969 Cysteine desulfurase-related, unknown function CLOST_2578 7bc2600e6719a56a2c1de1a6acbd0912 380 Pfam PF00266 Aminotransferase class-V 2 369 1.9E-95 T 13-10-2018 IPR000192 Aminotransferase class V domain CLOST_2578 7bc2600e6719a56a2c1de1a6acbd0912 380 PIRSF PIRSF005572 1 379 4.3E-66 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 CLOST_2578 7bc2600e6719a56a2c1de1a6acbd0912 380 SUPERFAMILY SSF53383 1 377 1.32E-102 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_2386 51dfc5ec541d5e857af34f231345a315 223 Gene3D G3DSA:3.60.15.10 1 223 9.1E-79 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_2386 51dfc5ec541d5e857af34f231345a315 223 Pfam PF12706 Beta-lactamase superfamily domain 18 192 3.5E-25 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_2386 51dfc5ec541d5e857af34f231345a315 223 SUPERFAMILY SSF56281 1 207 4.85E-37 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_2386 51dfc5ec541d5e857af34f231345a315 223 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 223 36.163 T 13-10-2018 IPR022877 Protein of unknown funcion UPF0173 CLOST_2386 51dfc5ec541d5e857af34f231345a315 223 SMART SM00849 7 191 1.1E-10 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 SUPERFAMILY SSF161070 6 499 2.48E-109 T 13-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 Pfam PF00209 Sodium:neurotransmitter symporter family 158 495 1.5E-25 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 Pfam PF00209 Sodium:neurotransmitter symporter family 6 134 1.1E-23 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 403 423 7.0E-18 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 14 35 7.0E-18 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 320 339 7.0E-18 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 443 463 7.0E-18 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 43 62 7.0E-18 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CLOST_1645 5dfa4cd3e215eb08742e1d5218540649 527 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 30 44 - T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CLOST_2320 7f692b422fe2a8b149ac7a3e7d0e57d0 659 Pfam PF01496 V-type ATPase 116kDa subunit family 550 650 2.9E-10 T 13-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2320 7f692b422fe2a8b149ac7a3e7d0e57d0 659 Pfam PF01496 V-type ATPase 116kDa subunit family 36 430 3.3E-28 T 13-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 571 587 1.1E-13 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 652 671 1.1E-13 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 65 84 1.1E-13 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 682 701 1.1E-13 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 712 730 1.1E-13 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 655 758 7.2E-10 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 Pfam PF13654 AAA domain 29 545 6.5E-190 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 Gene3D G3DSA:3.40.50.300 9 167 1.0E-25 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 Gene3D G3DSA:3.40.50.300 257 455 7.6E-59 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 Gene3D G3DSA:3.30.230.10 547 783 1.5E-97 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 Gene3D G3DSA:1.10.8.60 456 543 3.8E-11 T 13-10-2018 CLOST_2105 506c61088ee01009bfe2a8b8f060d50e 792 SUPERFAMILY SSF54211 569 762 4.55E-33 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_2201 f7c2945c1365c6b0fd433429ed9419bd 256 SUPERFAMILY SSF52540 4 253 1.13E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2201 f7c2945c1365c6b0fd433429ed9419bd 256 Gene3D G3DSA:3.40.50.300 1 253 2.9E-62 T 13-10-2018 CLOST_2201 f7c2945c1365c6b0fd433429ed9419bd 256 SMART SM00382 29 229 2.8E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2201 f7c2945c1365c6b0fd433429ed9419bd 256 Pfam PF00005 ABC transporter 22 180 1.2E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2201 f7c2945c1365c6b0fd433429ed9419bd 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 252 3.9E-7 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CLOST_1307 1b1179c2db3486d97a2627b07000df10 777 Gene3D G3DSA:3.90.1640.30 42 307 1.7E-88 T 13-10-2018 CLOST_1307 1b1179c2db3486d97a2627b07000df10 777 Gene3D G3DSA:3.10.310.30 308 431 4.5E-35 T 13-10-2018 CLOST_1307 1b1179c2db3486d97a2627b07000df10 777 Pfam PF01368 DHH family 68 202 2.3E-11 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_1307 1b1179c2db3486d97a2627b07000df10 777 Pfam PF02272 DHHA1 domain 304 424 2.8E-21 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CLOST_1307 1b1179c2db3486d97a2627b07000df10 777 SUPERFAMILY SSF64182 42 439 1.83E-114 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily CLOST_1307 1b1179c2db3486d97a2627b07000df10 777 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 17 544 7.0E-166 T 13-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CLOST_0468 dc7687580576b1505a701b3200c7e384 289 SUPERFAMILY SSF53335 16 286 7.86E-76 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0468 dc7687580576b1505a701b3200c7e384 289 SMART SM00650 35 210 1.2E-76 T 13-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CLOST_0468 dc7687580576b1505a701b3200c7e384 289 Pfam PF00398 Ribosomal RNA adenine dimethylase 19 284 2.5E-69 T 13-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CLOST_0468 dc7687580576b1505a701b3200c7e384 289 Gene3D G3DSA:1.10.8.100 218 286 2.5E-21 T 13-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CLOST_0468 dc7687580576b1505a701b3200c7e384 289 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 19 282 7.1E-82 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CLOST_0468 dc7687580576b1505a701b3200c7e384 289 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 19 284 53.701 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CLOST_0468 dc7687580576b1505a701b3200c7e384 289 Gene3D G3DSA:3.40.50.150 1 212 1.6E-74 T 13-10-2018 CLOST_0468 dc7687580576b1505a701b3200c7e384 289 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 78 - T 13-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 179 196 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 SUPERFAMILY SSF53067 117 346 2.39E-44 T 13-10-2018 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 Pfam PF00871 Acetokinase family 5 332 9.6E-59 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 SUPERFAMILY SSF53067 3 172 3.88E-62 T 13-10-2018 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 Gene3D G3DSA:3.30.420.40 137 330 3.3E-145 T 13-10-2018 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 Gene3D G3DSA:3.30.420.40 5 353 3.3E-145 T 13-10-2018 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 PIRSF PIRSF036458 1 354 1.1E-148 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 Hamap MF_00542 Probable butyrate kinase [buk]. 1 355 144.483 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 5 350 1.9E-148 T 13-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 PRINTS PR00471 Acetate kinase family signature 295 311 2.6E-16 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 PRINTS PR00471 Acetate kinase family signature 179 200 2.6E-16 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 PRINTS PR00471 Acetate kinase family signature 5 16 2.6E-16 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0208 20528efadb5a500d70491d982b2060ca 355 PRINTS PR00471 Acetate kinase family signature 272 285 2.6E-16 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 PIRSF PIRSF034834 1 176 7.6E-56 T 13-10-2018 IPR011238 Polyhedral organelle shell protein PduT CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 55 6.0E-19 T 13-10-2018 CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 90 148 8.0E-11 T 13-10-2018 CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 Gene3D G3DSA:3.30.70.1710 1 73 2.4E-24 T 13-10-2018 CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 SUPERFAMILY SSF143414 1 84 1.14E-21 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 Gene3D G3DSA:3.30.70.1710 74 176 1.4E-27 T 13-10-2018 CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 Pfam PF00936 BMC domain 90 167 2.2E-19 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 Pfam PF00936 BMC domain 1 70 7.9E-20 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 SMART SM00877 1 71 4.6E-18 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 SMART SM00877 89 167 8.1E-24 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0261 b62d9680d9f8d8ee912a9fe10e758c2a 176 SUPERFAMILY SSF143414 89 175 2.49E-20 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0856 3ecd680b9480af22dea6af753b139996 348 Gene3D G3DSA:1.20.81.30 200 312 3.6E-17 T 13-10-2018 CLOST_0856 3ecd680b9480af22dea6af753b139996 348 Pfam PF00482 Type II secretion system (T2SS), protein F 219 339 4.5E-17 T 13-10-2018 IPR018076 Type II secretion system F domain CLOST_0856 3ecd680b9480af22dea6af753b139996 348 Pfam PF00482 Type II secretion system (T2SS), protein F 15 137 2.8E-28 T 13-10-2018 IPR018076 Type II secretion system F domain CLOST_0856 3ecd680b9480af22dea6af753b139996 348 PRINTS PR00812 Bacterial general secretion pathway protein F signature 11 23 4.1E-12 T 13-10-2018 IPR003004 GspF/PilC family CLOST_0856 3ecd680b9480af22dea6af753b139996 348 PRINTS PR00812 Bacterial general secretion pathway protein F signature 312 326 4.1E-12 T 13-10-2018 IPR003004 GspF/PilC family CLOST_0856 3ecd680b9480af22dea6af753b139996 348 PRINTS PR00812 Bacterial general secretion pathway protein F signature 328 347 4.1E-12 T 13-10-2018 IPR003004 GspF/PilC family CLOST_0856 3ecd680b9480af22dea6af753b139996 348 PRINTS PR00812 Bacterial general secretion pathway protein F signature 109 137 4.1E-12 T 13-10-2018 IPR003004 GspF/PilC family CLOST_0856 3ecd680b9480af22dea6af753b139996 348 Gene3D G3DSA:1.20.81.30 1 116 1.9E-29 T 13-10-2018 CLOST_1949 9a6baf17f7d24aa09ea0d411247ddbfe 116 Pfam PF07892 Protein of unknown function (DUF1667) 29 110 8.8E-36 T 13-10-2018 IPR012460 Protein of unknown function DUF1667 CLOST_1949 9a6baf17f7d24aa09ea0d411247ddbfe 116 SUPERFAMILY SSF160148 41 114 4.32E-28 T 13-10-2018 IPR036593 CPE0013-like superfamily CLOST_1949 9a6baf17f7d24aa09ea0d411247ddbfe 116 Gene3D G3DSA:3.10.530.10 42 110 1.2E-25 T 13-10-2018 IPR036593 CPE0013-like superfamily CLOST_0303 8977fa10f262b0e08a71b9f5f858810e 454 Pfam PF05272 Virulence-associated protein E 129 308 4.3E-47 T 13-10-2018 IPR007936 Virulence-associated E CLOST_0303 8977fa10f262b0e08a71b9f5f858810e 454 SUPERFAMILY SSF52540 153 281 1.27E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1969 969b6dc63eb1679439cedba875ecb758 405 Gene3D G3DSA:3.90.220.20 4 183 9.8E-38 T 13-10-2018 CLOST_1969 969b6dc63eb1679439cedba875ecb758 405 Gene3D G3DSA:3.90.220.20 189 377 1.0E-32 T 13-10-2018 CLOST_1969 969b6dc63eb1679439cedba875ecb758 405 SUPERFAMILY SSF116734 15 203 3.27E-45 T 13-10-2018 CLOST_1969 969b6dc63eb1679439cedba875ecb758 405 Pfam PF01420 Type I restriction modification DNA specificity domain 15 185 3.1E-26 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CLOST_1969 969b6dc63eb1679439cedba875ecb758 405 Pfam PF01420 Type I restriction modification DNA specificity domain 208 384 7.9E-38 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CLOST_1969 969b6dc63eb1679439cedba875ecb758 405 SUPERFAMILY SSF116734 208 399 6.54E-42 T 13-10-2018 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 SUPERFAMILY SSF56712 3 624 3.79E-137 T 13-10-2018 IPR023405 DNA topoisomerase, type IA, core domain CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 383 399 3.3E-24 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 286 295 3.3E-24 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 504 518 3.3E-24 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 53 66 3.3E-24 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 151 169 3.3E-24 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 SMART SM00437 244 543 1.8E-67 T 13-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 Gene3D G3DSA:1.10.290.10 253 397 1.9E-136 T 13-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 Gene3D G3DSA:3.40.50.140 1 107 6.9E-26 T 13-10-2018 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 Gene3D G3DSA:1.10.460.10 114 589 1.9E-136 T 13-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 Gene3D G3DSA:2.70.20.10 175 472 1.9E-136 T 13-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 281 295 - T 13-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 SMART SM00436 80 181 3.1E-23 T 13-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CLOST_0824 76ac607f1cf29c27600e137919f62e18 702 Pfam PF01131 DNA topoisomerase 106 581 6.1E-104 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CLOST_0982 00cde0091587645c2ecd8c99e9d10ea0 305 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 2 291 4.4E-72 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CLOST_0982 00cde0091587645c2ecd8c99e9d10ea0 305 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 305 85.228 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CLOST_0982 00cde0091587645c2ecd8c99e9d10ea0 305 Pfam PF03186 CobD/Cbib protein 1 284 4.9E-95 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CLOST_2038 880f671fcad3262f0be736649ab6f8c4 349 SUPERFAMILY SSF53098 189 341 7.89E-22 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_2038 880f671fcad3262f0be736649ab6f8c4 349 Gene3D G3DSA:3.30.420.10 180 344 3.9E-6 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_2038 880f671fcad3262f0be736649ab6f8c4 349 Pfam PF00665 Integrase core domain 189 299 2.8E-8 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 CLOST_2038 880f671fcad3262f0be736649ab6f8c4 349 Pfam PF13936 Helix-turn-helix domain 13 55 2.0E-11 T 13-10-2018 IPR025246 Transposase IS30-like HTH domain CLOST_2493 75d4f075da6b528526f1c4763699e77e 234 Pfam PF01381 Helix-turn-helix 10 62 4.3E-15 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2493 75d4f075da6b528526f1c4763699e77e 234 SUPERFAMILY SSF47413 1 66 4.02E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_2493 75d4f075da6b528526f1c4763699e77e 234 SMART SM00530 6 62 5.0E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2493 75d4f075da6b528526f1c4763699e77e 234 Gene3D G3DSA:1.10.260.40 1 66 5.5E-20 T 13-10-2018 CLOST_1393 a1e72d3e5e969f925fdad70bec712f6c 162 Pfam PF04093 rod shape-determining protein MreD 3 158 5.9E-11 T 13-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CLOST_1393 a1e72d3e5e969f925fdad70bec712f6c 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 4 151 1.0E-15 T 13-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CLOST_1606 505346faa75932dbfd2a7ad8bf5e11dc 212 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 208 1.2E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_1606 505346faa75932dbfd2a7ad8bf5e11dc 212 SUPERFAMILY SSF161098 12 194 9.55E-44 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1606 505346faa75932dbfd2a7ad8bf5e11dc 212 Gene3D G3DSA:1.10.3720.10 1 211 4.1E-56 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1606 505346faa75932dbfd2a7ad8bf5e11dc 212 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 103 1.1E-24 T 13-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 CLOST_1501 a6c9d58b2aaa932d40383365dd4c37a6 149 SMART SM00530 29 83 0.0039 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1501 a6c9d58b2aaa932d40383365dd4c37a6 149 SUPERFAMILY SSF47413 26 86 4.38E-7 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_1501 a6c9d58b2aaa932d40383365dd4c37a6 149 Gene3D G3DSA:1.10.260.40 27 93 1.0E-6 T 13-10-2018 CLOST_1501 a6c9d58b2aaa932d40383365dd4c37a6 149 Pfam PF01381 Helix-turn-helix 31 80 2.3E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1368 62aded842a1c43b0adf4cc2d7b830f52 192 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 8 180 1.4E-44 T 13-10-2018 IPR005249 Conserved hypothetical protein CHP00488 CLOST_1368 62aded842a1c43b0adf4cc2d7b830f52 192 SMART SM00471 12 140 3.3E-6 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_1368 62aded842a1c43b0adf4cc2d7b830f52 192 SUPERFAMILY SSF109604 5 180 2.16E-28 T 13-10-2018 CLOST_1368 62aded842a1c43b0adf4cc2d7b830f52 192 Gene3D G3DSA:1.10.3210.10 1 184 8.1E-53 T 13-10-2018 CLOST_1368 62aded842a1c43b0adf4cc2d7b830f52 192 Pfam PF01966 HD domain 16 129 4.6E-13 T 13-10-2018 IPR006674 HD domain CLOST_1831 068835fee27d70cc3dd5b57047d6df52 152 SUPERFAMILY SSF55826 4 150 3.53E-38 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 CLOST_1831 068835fee27d70cc3dd5b57047d6df52 152 Pfam PF04073 Aminoacyl-tRNA editing domain 24 141 1.2E-25 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CLOST_1831 068835fee27d70cc3dd5b57047d6df52 152 Gene3D G3DSA:3.90.960.10 1 152 9.0E-44 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 CLOST_0029 3bb41f599ce31d518e457abfc25eef4a 295 SUPERFAMILY SSF53850 26 294 1.57E-70 T 13-10-2018 CLOST_0029 3bb41f599ce31d518e457abfc25eef4a 295 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 26 291 8.4E-66 T 13-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 CLOST_0029 3bb41f599ce31d518e457abfc25eef4a 295 Gene3D G3DSA:3.40.190.10 29 290 2.5E-99 T 13-10-2018 CLOST_0029 3bb41f599ce31d518e457abfc25eef4a 295 Gene3D G3DSA:3.40.190.120 131 234 2.5E-99 T 13-10-2018 CLOST_0580 92505693d72be5e49400655a82095836 570 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 36 50 8.3E-12 T 13-10-2018 CLOST_0580 92505693d72be5e49400655a82095836 570 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 116 128 8.3E-12 T 13-10-2018 CLOST_0580 92505693d72be5e49400655a82095836 570 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 153 177 8.3E-12 T 13-10-2018 CLOST_0580 92505693d72be5e49400655a82095836 570 Pfam PF07669 Eco57I restriction-modification methylase 116 228 1.0E-11 T 13-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 CLOST_0580 92505693d72be5e49400655a82095836 570 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOST_0580 92505693d72be5e49400655a82095836 570 SUPERFAMILY SSF53335 2 232 3.92E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0580 92505693d72be5e49400655a82095836 570 Gene3D G3DSA:3.40.50.150 1 299 3.6E-43 T 13-10-2018 CLOST_0580 92505693d72be5e49400655a82095836 570 Pfam PF12950 TaqI-like C-terminal specificity domain 376 523 4.6E-14 T 13-10-2018 IPR025931 TaqI-like C-terminal specificity domain CLOST_2490 41c2caad4580e173b7b78c7583ac5367 249 SUPERFAMILY SSF46955 125 210 1.87E-18 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily CLOST_2490 41c2caad4580e173b7b78c7583ac5367 249 Gene3D G3DSA:1.10.1660.10 1 115 1.3E-16 T 13-10-2018 CLOST_2490 41c2caad4580e173b7b78c7583ac5367 249 Gene3D G3DSA:1.10.1660.10 116 248 6.4E-21 T 13-10-2018 CLOST_2490 41c2caad4580e173b7b78c7583ac5367 249 Pfam PF00376 MerR family regulatory protein 5 42 1.3E-9 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_2490 41c2caad4580e173b7b78c7583ac5367 249 SMART SM00422 125 193 6.6E-10 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_2490 41c2caad4580e173b7b78c7583ac5367 249 SMART SM00422 4 66 7.2E-7 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_2490 41c2caad4580e173b7b78c7583ac5367 249 SUPERFAMILY SSF46955 4 115 4.44E-13 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily CLOST_2490 41c2caad4580e173b7b78c7583ac5367 249 Pfam PF13411 MerR HTH family regulatory protein 128 191 7.5E-14 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CLOST_2566 e16da5c379d3e87d3c81d3dc0187b783 661 Pfam PF02272 DHHA1 domain 549 653 2.2E-11 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CLOST_2566 e16da5c379d3e87d3c81d3dc0187b783 661 Gene3D G3DSA:3.30.450.20 50 170 3.7E-11 T 13-10-2018 CLOST_2566 e16da5c379d3e87d3c81d3dc0187b783 661 Gene3D G3DSA:3.90.1640.10 330 544 1.5E-53 T 13-10-2018 CLOST_2566 e16da5c379d3e87d3c81d3dc0187b783 661 Pfam PF01368 DHH family 348 502 3.1E-21 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_2566 e16da5c379d3e87d3c81d3dc0187b783 661 SUPERFAMILY SSF64182 346 639 1.7E-59 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily CLOST_2566 e16da5c379d3e87d3c81d3dc0187b783 661 Gene3D G3DSA:3.10.310.30 571 659 1.3E-10 T 13-10-2018 CLOST_2566 e16da5c379d3e87d3c81d3dc0187b783 661 PIRSF PIRSF026583 1 661 3.0E-206 T 13-10-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CLOST_2066 30aa835d7e8d18288c573856a4722403 137 Gene3D G3DSA:2.60.320.10 27 133 5.9E-15 T 13-10-2018 IPR038690 NusG, domain 2 superfamily CLOST_2066 30aa835d7e8d18288c573856a4722403 137 Pfam PF07009 NusG domain II 11 123 2.6E-20 T 13-10-2018 IPR024045 NusG, domain 2 CLOST_1363 b05a6e24bbd22949effff82d389a6248 143 SUPERFAMILY SSF52540 4 109 2.04E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1363 b05a6e24bbd22949effff82d389a6248 143 Gene3D G3DSA:3.40.50.300 3 136 4.1E-5 T 13-10-2018 CLOST_0337 eb6ab6729ebacd7ebd493b184388e115 188 Pfam PF00551 Formyl transferase 5 182 1.2E-43 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CLOST_0337 eb6ab6729ebacd7ebd493b184388e115 188 SUPERFAMILY SSF53328 4 187 8.63E-48 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CLOST_0337 eb6ab6729ebacd7ebd493b184388e115 188 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 5 188 28.011 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CLOST_0337 eb6ab6729ebacd7ebd493b184388e115 188 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 132 155 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CLOST_0337 eb6ab6729ebacd7ebd493b184388e115 188 Gene3D G3DSA:3.40.50.170 1 188 1.4E-62 T 13-10-2018 CLOST_0337 eb6ab6729ebacd7ebd493b184388e115 188 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 5 187 8.0E-50 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CLOST_2398 b94cf7b21940444a174ee0fa7c47d8a6 188 Pfam PF02632 BioY family 29 177 2.7E-41 T 13-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CLOST_2398 b94cf7b21940444a174ee0fa7c47d8a6 188 PIRSF PIRSF016661 1 186 3.0E-47 T 13-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CLOST_2398 b94cf7b21940444a174ee0fa7c47d8a6 188 Gene3D G3DSA:1.10.1760.20 1 184 1.5E-57 T 13-10-2018 CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 Pfam PF02421 Ferrous iron transport protein B 6 159 3.1E-70 T 13-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 Gene3D G3DSA:3.40.50.300 7 193 8.0E-47 T 13-10-2018 CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 12 590 1.3E-197 T 13-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 Pfam PF07664 Ferrous iron transport protein B C terminus 412 464 3.2E-24 T 13-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 Pfam PF07670 Nucleoside recognition 310 399 4.3E-11 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 Pfam PF07670 Nucleoside recognition 470 593 1.4E-27 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 SUPERFAMILY SSF52540 5 163 2.03E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 8 28 3.6E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_0265 ff48901edff3383db3742eb38a49c7ee 623 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 29 47 3.6E-5 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_1361 f269bd05c11945cce04c79a2b37dd2de 205 Gene3D G3DSA:3.10.560.10 53 149 1.2E-8 T 13-10-2018 CLOST_1361 f269bd05c11945cce04c79a2b37dd2de 205 Pfam PF12836 Helix-hairpin-helix motif 141 203 4.7E-20 T 13-10-2018 CLOST_1361 f269bd05c11945cce04c79a2b37dd2de 205 SUPERFAMILY SSF47781 139 204 6.23E-23 T 13-10-2018 IPR010994 RuvA domain 2-like CLOST_1361 f269bd05c11945cce04c79a2b37dd2de 205 Gene3D G3DSA:1.10.150.310 150 205 1.3E-10 T 13-10-2018 CLOST_1361 f269bd05c11945cce04c79a2b37dd2de 205 Pfam PF10531 SLBB domain 67 110 2.3E-10 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1650 9152cf3cdbac507ecff1849b57fdf71f 270 Gene3D G3DSA:3.40.190.10 35 267 3.2E-105 T 13-10-2018 CLOST_1650 9152cf3cdbac507ecff1849b57fdf71f 270 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 14 268 6.6E-69 T 13-10-2018 IPR004872 Lipoprotein NlpA family CLOST_1650 9152cf3cdbac507ecff1849b57fdf71f 270 Gene3D G3DSA:3.40.190.10 116 220 3.2E-105 T 13-10-2018 CLOST_1650 9152cf3cdbac507ecff1849b57fdf71f 270 SUPERFAMILY SSF53850 35 270 1.57E-90 T 13-10-2018 CLOST_1650 9152cf3cdbac507ecff1849b57fdf71f 270 PIRSF PIRSF002854 1 270 1.1E-111 T 13-10-2018 IPR004872 Lipoprotein NlpA family CLOST_1650 9152cf3cdbac507ecff1849b57fdf71f 270 Pfam PF03180 NLPA lipoprotein 35 270 8.0E-105 T 13-10-2018 IPR004872 Lipoprotein NlpA family CLOST_0259 3c2824f8ece1cbb3f0c0971d241957a9 86 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 12 81 4.0E-18 T 13-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CLOST_0259 3c2824f8ece1cbb3f0c0971d241957a9 86 SUPERFAMILY SSF159133 1 82 5.36E-28 T 13-10-2018 IPR036677 EutN/Ccml superfamily CLOST_0259 3c2824f8ece1cbb3f0c0971d241957a9 86 Gene3D G3DSA:2.40.50.220 1 85 8.8E-32 T 13-10-2018 IPR036677 EutN/Ccml superfamily CLOST_0259 3c2824f8ece1cbb3f0c0971d241957a9 86 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 81 2.2E-30 T 13-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml CLOST_0180 71188fc848c4f12d2912c12b584f5217 889 Gene3D G3DSA:3.40.630.10 162 466 3.1E-29 T 13-10-2018 CLOST_0180 71188fc848c4f12d2912c12b584f5217 889 SUPERFAMILY SSF53187 159 449 1.08E-34 T 13-10-2018 CLOST_0180 71188fc848c4f12d2912c12b584f5217 889 Pfam PF00246 Zinc carboxypeptidase 185 445 1.4E-9 T 13-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CLOST_1475 833b387c79d6e8ec712cbe279c933a9e 465 Pfam PF00682 HMGL-like 3 269 5.9E-49 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CLOST_1475 833b387c79d6e8ec712cbe279c933a9e 465 Pfam PF02436 Conserved carboxylase domain 296 445 2.7E-53 T 13-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CLOST_1475 833b387c79d6e8ec712cbe279c933a9e 465 SUPERFAMILY SSF51569 1 280 3.85E-89 T 13-10-2018 CLOST_1475 833b387c79d6e8ec712cbe279c933a9e 465 Gene3D G3DSA:3.20.20.70 1 457 6.7E-171 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1475 833b387c79d6e8ec712cbe279c933a9e 465 SUPERFAMILY SSF89000 299 444 1.96E-51 T 13-10-2018 CLOST_1097 feca12f9befce9a7c472da4d00024834 134 Gene3D G3DSA:3.30.1330.70 3 124 3.4E-11 T 13-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 CLOST_1097 feca12f9befce9a7c472da4d00024834 134 Pfam PF05866 Endodeoxyribonuclease RusA 7 119 7.8E-21 T 13-10-2018 IPR008822 Holliday junction resolvase RusA-like GO:0000287|GO:0006281|GO:0006310 CLOST_1097 feca12f9befce9a7c472da4d00024834 134 SUPERFAMILY SSF103084 1 121 1.31E-20 T 13-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 CLOST_0278 0f3381665401a635c063bc97a0634999 184 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 3 181 1.7E-63 T 13-10-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CLOST_0278 0f3381665401a635c063bc97a0634999 184 Gene3D G3DSA:3.40.50.2020 1 184 1.9E-55 T 13-10-2018 CLOST_0278 0f3381665401a635c063bc97a0634999 184 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 184 23.22 T 13-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0278 0f3381665401a635c063bc97a0634999 184 Pfam PF00156 Phosphoribosyl transferase domain 42 145 1.1E-11 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CLOST_0278 0f3381665401a635c063bc97a0634999 184 SUPERFAMILY SSF53271 4 144 9.12E-35 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like CLOST_0684 07707ff2075717bcce30328695ed37d3 249 Pfam PF01144 Coenzyme A transferase 18 209 1.8E-17 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 CLOST_0684 07707ff2075717bcce30328695ed37d3 249 Gene3D G3DSA:3.40.1080.10 10 244 9.9E-55 T 13-10-2018 CLOST_0684 07707ff2075717bcce30328695ed37d3 249 SMART SM00882 16 210 3.0E-5 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 CLOST_0684 07707ff2075717bcce30328695ed37d3 249 SUPERFAMILY SSF100950 11 245 1.59E-48 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_1159 0556f383f70f0e6b11f90da32de00df5 176 Gene3D G3DSA:3.40.920.10 2 176 1.5E-51 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1159 0556f383f70f0e6b11f90da32de00df5 176 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 173 9.3E-33 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CLOST_1159 0556f383f70f0e6b11f90da32de00df5 176 SUPERFAMILY SSF53323 4 176 3.14E-42 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1664 a02e8d3a7c95ea331acf856534ed0af9 304 SUPERFAMILY SSF102114 5 271 8.37E-40 T 13-10-2018 CLOST_1664 a02e8d3a7c95ea331acf856534ed0af9 304 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 303 7.9E-98 T 13-10-2018 IPR005911 Protein YhcC-like GO:0051536 CLOST_1664 a02e8d3a7c95ea331acf856534ed0af9 304 SMART SM00729 23 250 4.4E-26 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1664 a02e8d3a7c95ea331acf856534ed0af9 304 Gene3D G3DSA:3.80.30.20 41 235 2.8E-9 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1664 a02e8d3a7c95ea331acf856534ed0af9 304 Pfam PF16199 Radical_SAM C-terminal domain 211 293 6.2E-24 T 13-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CLOST_1664 a02e8d3a7c95ea331acf856534ed0af9 304 Pfam PF04055 Radical SAM superfamily 44 206 1.3E-14 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 SUPERFAMILY SSF47917 447 556 1.6E-21 T 13-10-2018 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 3 587 48.139 T 13-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 SUPERFAMILY SSF52540 180 438 1.6E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 86 205 1.3E-38 T 13-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 Gene3D G3DSA:1.10.1140.10 436 591 6.1E-42 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 10 70 6.3E-10 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 Gene3D G3DSA:2.40.50.100 117 187 3.1E-166 T 13-10-2018 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 SUPERFAMILY SSF50615 7 73 1.18E-10 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 Gene3D G3DSA:2.40.30.20 2 73 2.3E-25 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 214 435 1.6E-90 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CLOST_2316 7c13fdd38d3c5f01db5b52c2dc54c2e4 594 Gene3D G3DSA:3.40.50.300 74 435 3.1E-166 T 13-10-2018 CLOST_0388 eae1b04a90f979ad735d6f861b8fac5d 212 Gene3D G3DSA:3.40.225.10 2 212 6.9E-75 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CLOST_0388 eae1b04a90f979ad735d6f861b8fac5d 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 182 3.6E-46 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal CLOST_0388 eae1b04a90f979ad735d6f861b8fac5d 212 SUPERFAMILY SSF53639 4 209 4.51E-60 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CLOST_0388 eae1b04a90f979ad735d6f861b8fac5d 212 SMART SM01007 7 183 4.8E-63 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal CLOST_2438 f73ed86e690af247a46900cfe221f4ea 269 SUPERFAMILY SSF53850 36 263 2.0E-60 T 13-10-2018 CLOST_2438 f73ed86e690af247a46900cfe221f4ea 269 Gene3D G3DSA:3.40.190.10 40 259 6.9E-64 T 13-10-2018 CLOST_2438 f73ed86e690af247a46900cfe221f4ea 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 260 4.4E-61 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_2438 f73ed86e690af247a46900cfe221f4ea 269 SMART SM00062 38 262 7.4E-70 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CLOST_2438 f73ed86e690af247a46900cfe221f4ea 269 Gene3D G3DSA:3.40.190.10 106 223 6.9E-64 T 13-10-2018 CLOST_0132 907adf201e0c6a12b0d73196ae021222 521 Gene3D G3DSA:1.10.287.130 379 478 3.3E-16 T 13-10-2018 CLOST_0132 907adf201e0c6a12b0d73196ae021222 521 Gene3D G3DSA:3.30.450.20 194 282 7.9E-16 T 13-10-2018 CLOST_0132 907adf201e0c6a12b0d73196ae021222 521 SUPERFAMILY SSF103190 87 197 1.65E-8 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0132 907adf201e0c6a12b0d73196ae021222 521 Gene3D G3DSA:1.20.1480.50 283 378 4.1E-9 T 13-10-2018 CLOST_0132 907adf201e0c6a12b0d73196ae021222 521 Pfam PF02743 Cache domain 37 279 2.3E-25 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_0132 907adf201e0c6a12b0d73196ae021222 521 Gene3D G3DSA:3.30.450.20 132 193 7.9E-16 T 13-10-2018 CLOST_0082 7be3557bb86c0595a4c954bfc62386cf 350 SUPERFAMILY SSF51726 8 348 4.71E-63 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0082 7be3557bb86c0595a4c954bfc62386cf 350 Gene3D G3DSA:3.20.20.210 3 346 3.0E-83 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 CLOST_0082 7be3557bb86c0595a4c954bfc62386cf 350 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 10 345 8.9E-72 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CLOST_0091 11b41f600c3111c54fcc6263e0a1622b 282 Gene3D G3DSA:3.40.190.10 128 232 1.9E-73 T 13-10-2018 CLOST_0091 11b41f600c3111c54fcc6263e0a1622b 282 SUPERFAMILY SSF53850 46 282 1.71E-57 T 13-10-2018 CLOST_0091 11b41f600c3111c54fcc6263e0a1622b 282 Pfam PF03180 NLPA lipoprotein 46 281 6.7E-62 T 13-10-2018 IPR004872 Lipoprotein NlpA family CLOST_0091 11b41f600c3111c54fcc6263e0a1622b 282 Gene3D G3DSA:3.40.190.10 53 280 1.9E-73 T 13-10-2018 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 Gene3D G3DSA:3.40.630.10 44 456 4.9E-146 T 13-10-2018 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 32 464 3.8E-88 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 SUPERFAMILY SSF101821 108 244 4.85E-32 T 13-10-2018 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 Gene3D G3DSA:2.30.250.10 107 249 4.9E-146 T 13-10-2018 IPR023358 Peptidase M18, domain 2 GO:0004177 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 SUPERFAMILY SSF53187 8 466 1.42E-100 T 13-10-2018 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 96 112 2.2E-28 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 165 182 2.2E-28 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 129 149 2.2E-28 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 294 312 2.2E-28 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 338 354 2.2E-28 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_1455 a208fdadbb2545d4e64e5427ecf383f6 466 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 432 447 2.2E-28 T 13-10-2018 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 CLOST_1088 bb1fea55446a28caaa30ee8e31d217a0 116 TIGRFAM TIGR04535 ferrit_encaps: ferritin-like protein 4 116 1.9E-51 T 13-10-2018 IPR030907 Ferritin-like protein CLOST_1088 bb1fea55446a28caaa30ee8e31d217a0 116 SUPERFAMILY SSF47240 3 91 1.22E-21 T 13-10-2018 IPR009078 Ferritin-like superfamily CLOST_0935 1a143bd54c7242b0bec59c00f1855e1e 141 SUPERFAMILY SSF50814 3 139 1.9E-31 T 13-10-2018 IPR012674 Calycin CLOST_0935 1a143bd54c7242b0bec59c00f1855e1e 141 Gene3D G3DSA:2.40.128.20 2 141 4.8E-35 T 13-10-2018 IPR012674 Calycin CLOST_0935 1a143bd54c7242b0bec59c00f1855e1e 141 Pfam PF09148 Domain of unknown function (DUF1934) 6 137 4.2E-37 T 13-10-2018 IPR015231 Protein of unknown function DUF1934 CLOST_2477 0dae3647dd7db95752bd4b17e94c01f7 283 Gene3D G3DSA:3.40.50.300 30 256 5.9E-19 T 13-10-2018 CLOST_2477 0dae3647dd7db95752bd4b17e94c01f7 283 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 197 244 7.1E-12 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_2477 0dae3647dd7db95752bd4b17e94c01f7 283 SUPERFAMILY SSF52540 32 253 5.19E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2477 0dae3647dd7db95752bd4b17e94c01f7 283 SMART SM00382 46 257 0.0097 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1636 621de03f3dd1cdb82074f27ac88aa63d 134 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 24 113 7.0E-20 T 13-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CLOST_1636 621de03f3dd1cdb82074f27ac88aa63d 134 SUPERFAMILY SSF51316 1 133 2.3E-39 T 13-10-2018 IPR011057 Mss4-like superfamily CLOST_1636 621de03f3dd1cdb82074f27ac88aa63d 134 Gene3D G3DSA:2.170.150.70 3 119 5.1E-15 T 13-10-2018 CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 166 194 - T 13-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 Gene3D G3DSA:1.20.81.30 57 173 1.8E-34 T 13-10-2018 CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 67 79 3.6E-24 T 13-10-2018 IPR003004 GspF/PilC family CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 3.6E-24 T 13-10-2018 IPR003004 GspF/PilC family CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 385 404 3.6E-24 T 13-10-2018 IPR003004 GspF/PilC family CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 369 383 3.6E-24 T 13-10-2018 IPR003004 GspF/PilC family CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 Pfam PF00482 Type II secretion system (T2SS), protein F 274 396 3.7E-29 T 13-10-2018 IPR018076 Type II secretion system F domain CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 Pfam PF00482 Type II secretion system (T2SS), protein F 71 194 7.6E-33 T 13-10-2018 IPR018076 Type II secretion system F domain CLOST_0186 75a44ab8502c0d8a4c29bc61b21b36c7 405 Gene3D G3DSA:1.20.81.30 257 369 1.3E-27 T 13-10-2018 CLOST_1224 950779d52b797c03114786d994b72b36 62 Pfam PF12655 Domain of unknown function (DUF3787) 36 58 1.0E-7 T 13-10-2018 IPR024209 Protein of unknown function DUF3787 CLOST_2417 7d19a59e73a11172743d8cd20881390f 92 Pfam PF13474 SnoaL-like domain 11 64 6.1E-5 T 13-10-2018 IPR037401 SnoaL-like domain CLOST_0373 98cb2c3e2029fa7632eca8aed29022a6 296 Pfam PF13360 PQQ-like domain 51 240 1.8E-5 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat CLOST_0373 98cb2c3e2029fa7632eca8aed29022a6 296 SUPERFAMILY SSF63829 29 277 1.9E-16 T 13-10-2018 CLOST_0373 98cb2c3e2029fa7632eca8aed29022a6 296 Gene3D G3DSA:2.120.10.30 111 291 2.1E-11 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like CLOST_2579 b15a3ff32c273ebfe135aa169443e63b 255 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 6 179 4.8E-49 T 13-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CLOST_2579 b15a3ff32c273ebfe135aa169443e63b 255 Gene3D G3DSA:1.10.10.2830 82 195 8.4E-33 T 13-10-2018 CLOST_2579 b15a3ff32c273ebfe135aa169443e63b 255 SUPERFAMILY SSF110849 4 140 1.1E-29 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily CLOST_2579 b15a3ff32c273ebfe135aa169443e63b 255 Pfam PF02195 ParB-like nuclease domain 8 93 6.9E-23 T 13-10-2018 IPR003115 ParB/Sulfiredoxin CLOST_2579 b15a3ff32c273ebfe135aa169443e63b 255 Gene3D G3DSA:3.90.1530.30 20 81 2.4E-26 T 13-10-2018 CLOST_2579 b15a3ff32c273ebfe135aa169443e63b 255 SMART SM00470 7 94 8.1E-25 T 13-10-2018 IPR003115 ParB/Sulfiredoxin CLOST_1067 875ddc9073cffbe6990869457bf1821c 184 SUPERFAMILY SSF117457 5 175 8.76E-65 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 CLOST_1067 875ddc9073cffbe6990869457bf1821c 184 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 16 175 1.4E-56 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CLOST_1067 875ddc9073cffbe6990869457bf1821c 184 Gene3D G3DSA:3.20.130.10 1 176 1.3E-72 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 CLOST_1067 875ddc9073cffbe6990869457bf1821c 184 Pfam PF05683 Fumarase C-terminus 4 176 6.9E-62 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CLOST_1401 f38a72852c07d2ebce7cafe1a82fde9c 314 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 11 311 1.5E-105 T 13-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 CLOST_1401 f38a72852c07d2ebce7cafe1a82fde9c 314 Hamap MF_00462 Ion-translocating oxidoreductase complex subunit D [rsxD]. 6 312 25.077 T 13-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 CLOST_1401 f38a72852c07d2ebce7cafe1a82fde9c 314 Pfam PF03116 NQR2, RnfD, RnfE family 8 310 7.2E-118 T 13-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 Pfam PF01202 Shikimate kinase 10 152 4.7E-33 T 13-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 SUPERFAMILY SSF52540 1 162 1.7E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 Gene3D G3DSA:3.40.50.300 1 164 1.0E-39 T 13-10-2018 CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 Hamap MF_00109 Shikimate kinase [aroK]. 1 164 21.719 T 13-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 PRINTS PR01100 Shikimate kinase family signature 74 83 2.3E-14 T 13-10-2018 CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 PRINTS PR01100 Shikimate kinase family signature 4 19 2.3E-14 T 13-10-2018 CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 PRINTS PR01100 Shikimate kinase family signature 28 41 2.3E-14 T 13-10-2018 CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 PRINTS PR01100 Shikimate kinase family signature 56 64 2.3E-14 T 13-10-2018 CLOST_1594 4fb17c2d6761f22794840b088f68007d 166 PRINTS PR01100 Shikimate kinase family signature 96 113 2.3E-14 T 13-10-2018 CLOST_0610 86051364c56df7e5f8a86152ef317eee 739 SUPERFAMILY SSF58104 409 737 3.01E-52 T 13-10-2018 CLOST_0610 86051364c56df7e5f8a86152ef317eee 739 Gene3D G3DSA:1.10.287.950 450 738 2.0E-48 T 13-10-2018 CLOST_0610 86051364c56df7e5f8a86152ef317eee 739 Gene3D G3DSA:1.20.1480.50 340 441 6.1E-12 T 13-10-2018 CLOST_0610 86051364c56df7e5f8a86152ef317eee 739 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 535 687 9.4E-29 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0610 86051364c56df7e5f8a86152ef317eee 739 SMART SM00283 463 738 9.8E-33 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0610 86051364c56df7e5f8a86152ef317eee 739 Pfam PF02743 Cache domain 83 331 1.3E-20 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_2092 fadefe27dee3d2968f71294f89986554 220 SUPERFAMILY SSF52540 1 120 2.44E-11 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2092 fadefe27dee3d2968f71294f89986554 220 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 132 1.0E-24 T 13-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CLOST_2092 fadefe27dee3d2968f71294f89986554 220 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 111 2.8E-21 T 13-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CLOST_2092 fadefe27dee3d2968f71294f89986554 220 Gene3D G3DSA:3.40.50.300 1 161 1.2E-29 T 13-10-2018 CLOST_2487 cf081cb251479224f8d8e7c0330f7673 358 SUPERFAMILY SSF140931 91 278 7.19E-34 T 13-10-2018 IPR036597 Fido-like domain superfamily CLOST_2487 cf081cb251479224f8d8e7c0330f7673 358 Pfam PF02661 Fic/DOC family 113 211 7.0E-17 T 13-10-2018 IPR003812 Fido domain CLOST_2487 cf081cb251479224f8d8e7c0330f7673 358 PIRSF PIRSF038925 2 358 1.0E-102 T 13-10-2018 IPR026287 Adenosine monophosphate-protein transferase CLOST_2487 cf081cb251479224f8d8e7c0330f7673 358 Pfam PF13784 Fic/DOC family N-terminal 26 104 4.3E-25 T 13-10-2018 IPR025758 Fic/DOC N-terminal CLOST_2487 cf081cb251479224f8d8e7c0330f7673 358 Gene3D G3DSA:1.10.3290.10 24 285 1.2E-43 T 13-10-2018 IPR036597 Fido-like domain superfamily CLOST_1751 c7afd73c981ecdc187e243d3db290a78 428 Gene3D G3DSA:3.30.420.10 2 134 4.1E-38 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_1751 c7afd73c981ecdc187e243d3db290a78 428 Pfam PF02540 NAD synthase 170 241 1.5E-9 T 13-10-2018 IPR022310 NAD/GMP synthase CLOST_1751 c7afd73c981ecdc187e243d3db290a78 428 Gene3D G3DSA:3.40.50.620 164 331 2.2E-28 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1751 c7afd73c981ecdc187e243d3db290a78 428 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 169 424 1.6E-77 T 13-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 CLOST_1751 c7afd73c981ecdc187e243d3db290a78 428 SUPERFAMILY SSF52402 180 384 1.17E-37 T 13-10-2018 CLOST_1751 c7afd73c981ecdc187e243d3db290a78 428 SUPERFAMILY SSF53098 2 121 2.91E-28 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1751 c7afd73c981ecdc187e243d3db290a78 428 Pfam PF13456 Reverse transcriptase-like 7 121 2.7E-18 T 13-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CLOST_1790 1bf7205e28d02969c9f3b506f563d42a 248 SUPERFAMILY SSF88697 3 65 5.8E-14 T 13-10-2018 IPR015947 PUA-like superfamily CLOST_1790 1bf7205e28d02969c9f3b506f563d42a 248 PIRSF PIRSF015601 1 246 2.6E-66 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 CLOST_1790 1bf7205e28d02969c9f3b506f563d42a 248 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 245 5.6E-61 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 CLOST_1790 1bf7205e28d02969c9f3b506f563d42a 248 SUPERFAMILY SSF75217 72 243 1.53E-46 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases CLOST_1790 1bf7205e28d02969c9f3b506f563d42a 248 Gene3D G3DSA:2.40.240.20 1 68 1.2E-20 T 13-10-2018 CLOST_1790 1bf7205e28d02969c9f3b506f563d42a 248 Pfam PF04452 RNA methyltransferase 17 240 1.5E-71 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 CLOST_1790 1bf7205e28d02969c9f3b506f563d42a 248 Gene3D G3DSA:3.40.1280.10 71 248 1.0E-58 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CLOST_1563 b7336d2794a2022c94ecfa23902ee7dc 359 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 24 125 2.0E-9 T 13-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain CLOST_1563 b7336d2794a2022c94ecfa23902ee7dc 359 Gene3D G3DSA:3.90.1570.30 4 140 9.9E-8 T 13-10-2018 CLOST_1563 b7336d2794a2022c94ecfa23902ee7dc 359 PIRSF PIRSF035009 1 359 4.2E-132 T 13-10-2018 IPR017035 Uncharacterised conserved protein UCP035009, HsdR, All3000-type CLOST_0752 957fca23f2537d85b59e5c2743c8fc82 255 SUPERFAMILY SSF55781 64 252 3.01E-39 T 13-10-2018 CLOST_0752 957fca23f2537d85b59e5c2743c8fc82 255 Pfam PF09339 IclR helix-turn-helix domain 10 59 1.8E-10 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CLOST_0752 957fca23f2537d85b59e5c2743c8fc82 255 Gene3D G3DSA:1.10.10.10 7 77 2.1E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0752 957fca23f2537d85b59e5c2743c8fc82 255 Gene3D G3DSA:3.30.450.40 78 254 8.8E-50 T 13-10-2018 IPR029016 GAF-like domain superfamily CLOST_0752 957fca23f2537d85b59e5c2743c8fc82 255 SMART SM00346 8 96 1.0E-20 T 13-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CLOST_0752 957fca23f2537d85b59e5c2743c8fc82 255 Pfam PF01614 Bacterial transcriptional regulator 126 248 8.0E-30 T 13-10-2018 IPR014757 Transcription regulator IclR, C-terminal CLOST_0752 957fca23f2537d85b59e5c2743c8fc82 255 SUPERFAMILY SSF46785 8 79 2.16E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2217 caf534b0b3d1e593547473014b7df0db 68 Gene3D G3DSA:1.20.5.1030 9 65 1.7E-17 T 13-10-2018 IPR038379 SecE superfamily CLOST_2217 caf534b0b3d1e593547473014b7df0db 68 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 16 65 5.1E-19 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 CLOST_2217 caf534b0b3d1e593547473014b7df0db 68 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 15 63 7.5E-19 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_2217 caf534b0b3d1e593547473014b7df0db 68 Hamap MF_00422 Protein translocase subunit SecE [secE]. 9 64 12.166 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CLOST_1136 9ea0b6625e364a9285b7f5e4001e87dd 260 SMART SM00893 22 212 2.2E-61 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CLOST_1136 9ea0b6625e364a9285b7f5e4001e87dd 260 SUPERFAMILY SSF52402 1 256 1.19E-78 T 13-10-2018 CLOST_1136 9ea0b6625e364a9285b7f5e4001e87dd 260 PIRSF PIRSF000090 1 260 9.9E-95 T 13-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CLOST_1136 9ea0b6625e364a9285b7f5e4001e87dd 260 Gene3D G3DSA:3.40.50.620 1 260 2.9E-96 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1136 9ea0b6625e364a9285b7f5e4001e87dd 260 Pfam PF01012 Electron transfer flavoprotein domain 23 183 1.5E-48 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CLOST_1136 9ea0b6625e364a9285b7f5e4001e87dd 260 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 13-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CLOST_2163 e9f996c698679b2a0c928c9ab4f19eac 249 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 1.0E-62 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_2163 e9f996c698679b2a0c928c9ab4f19eac 249 Gene3D G3DSA:3.30.70.660 106 242 8.2E-47 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 CLOST_2163 e9f996c698679b2a0c928c9ab4f19eac 249 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 243 37.058 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_2163 e9f996c698679b2a0c928c9ab4f19eac 249 PIRSF PIRSF001430 1 249 1.0E-83 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_2163 e9f996c698679b2a0c928c9ab4f19eac 249 Pfam PF01416 tRNA pseudouridine synthase 143 244 3.7E-26 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_2163 e9f996c698679b2a0c928c9ab4f19eac 249 Pfam PF01416 tRNA pseudouridine synthase 8 103 2.0E-10 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_2163 e9f996c698679b2a0c928c9ab4f19eac 249 Gene3D G3DSA:3.30.70.580 1 105 5.9E-36 T 13-10-2018 CLOST_2163 e9f996c698679b2a0c928c9ab4f19eac 249 SUPERFAMILY SSF55120 1 244 7.77E-84 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CLOST_0798 5aaeb2e7eae722413b0193ab39c79b86 648 SUPERFAMILY SSF55073 489 644 1.65E-43 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0798 5aaeb2e7eae722413b0193ab39c79b86 648 SMART SM00267 473 642 2.2E-47 T 13-10-2018 IPR000160 GGDEF domain CLOST_0798 5aaeb2e7eae722413b0193ab39c79b86 648 Pfam PF00990 Diguanylate cyclase, GGDEF domain 484 637 2.8E-42 T 13-10-2018 IPR000160 GGDEF domain CLOST_0798 5aaeb2e7eae722413b0193ab39c79b86 648 Gene3D G3DSA:3.30.70.270 478 648 8.2E-53 T 13-10-2018 CLOST_0798 5aaeb2e7eae722413b0193ab39c79b86 648 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 483 640 7.5E-37 T 13-10-2018 IPR000160 GGDEF domain CLOST_0128 b26adf14c1a59322ba6a333b4a5916a6 105 Pfam PF01906 Putative heavy-metal-binding 1 101 2.0E-34 T 13-10-2018 IPR002765 Uncharacterised protein family UPF0145 CLOST_0128 b26adf14c1a59322ba6a333b4a5916a6 105 SUPERFAMILY SSF117782 1 102 3.79E-33 T 13-10-2018 IPR035439 UPF0145 domain superfamily CLOST_0128 b26adf14c1a59322ba6a333b4a5916a6 105 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 102 22.63 T 13-10-2018 IPR002765 Uncharacterised protein family UPF0145 CLOST_0128 b26adf14c1a59322ba6a333b4a5916a6 105 Gene3D G3DSA:3.30.110.70 1 105 4.7E-27 T 13-10-2018 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 295 8.4E-21 T 13-10-2018 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 8.4E-21 T 13-10-2018 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 8.4E-21 T 13-10-2018 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.4E-21 T 13-10-2018 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 8.4E-21 T 13-10-2018 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 296 9.2E-32 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 3.8E-16 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 3.8E-16 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 283 301 3.8E-16 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 3.8E-16 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 3.8E-16 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 3.8E-16 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 Gene3D G3DSA:3.50.50.60 119 253 1.8E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 Gene3D G3DSA:3.50.50.60 3 296 1.8E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1950 8b9ad4826904c1b16312ee2187375bad 417 SUPERFAMILY SSF51905 1 324 2.2E-38 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 Gene3D G3DSA:2.40.50.140 379 442 1.7E-16 T 13-10-2018 CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 3 440 64.111 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 SUPERFAMILY SSF102114 133 371 2.09E-56 T 13-10-2018 CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 438 7.5E-137 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 5 438 7.3E-152 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 Pfam PF00919 Uncharacterized protein family UPF0004 5 103 4.8E-29 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 SMART SM00729 146 364 2.9E-55 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 Gene3D G3DSA:3.80.30.20 143 378 2.4E-86 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 Gene3D G3DSA:3.40.50.12160 4 133 2.2E-42 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 Pfam PF04055 Radical SAM superfamily 152 322 5.8E-25 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1681 69a334118c68c571424cc7bb7b17340f 442 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 150 170 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 Gene3D G3DSA:2.30.30.20 316 357 5.6E-7 T 13-10-2018 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 297 6.5E-103 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 SUPERFAMILY SSF53671 1 299 1.31E-95 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 Gene3D G3DSA:3.40.50.1370 129 285 5.0E-110 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 141 2.6E-45 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 318 354 6.1E-9 T 13-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 300 35.852 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 SUPERFAMILY SSF57825 318 355 6.41E-9 T 13-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 Gene3D G3DSA:3.40.50.1370 2 294 5.0E-110 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 149 295 2.8E-31 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00101 Aspartate carbamoyltransferase signature 35 57 3.5E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00101 Aspartate carbamoyltransferase signature 74 83 3.5E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00101 Aspartate carbamoyltransferase signature 218 227 3.5E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00101 Aspartate carbamoyltransferase signature 279 293 3.5E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00101 Aspartate carbamoyltransferase signature 257 262 3.5E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00101 Aspartate carbamoyltransferase signature 128 145 3.5E-36 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 45 52 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 286 6.9E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 129 140 6.9E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 45 64 6.9E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_0273 2c2852bf27d53f6a1773baa86390b341 357 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 6.9E-26 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CLOST_1208 8c4c7c336119cd20de711f6082440a8e 414 Pfam PF11700 Vacuole effluxer Atg22 like 46 408 3.6E-51 T 13-10-2018 IPR024671 Autophagy-related protein 22-like CLOST_1208 8c4c7c336119cd20de711f6082440a8e 414 SUPERFAMILY SSF103473 18 409 5.75E-40 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_1208 8c4c7c336119cd20de711f6082440a8e 414 Gene3D G3DSA:1.20.1250.20 15 407 9.8E-32 T 13-10-2018 CLOST_1825 60d9efdffacd2e3ee76ee91b06cc81fd 271 SMART SM00382 33 222 3.4E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1825 60d9efdffacd2e3ee76ee91b06cc81fd 271 Gene3D G3DSA:3.40.50.300 1 262 1.2E-65 T 13-10-2018 CLOST_1825 60d9efdffacd2e3ee76ee91b06cc81fd 271 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1825 60d9efdffacd2e3ee76ee91b06cc81fd 271 Pfam PF00005 ABC transporter 24 172 3.9E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_1825 60d9efdffacd2e3ee76ee91b06cc81fd 271 SUPERFAMILY SSF52540 8 235 7.79E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2263 175d656286996dfee826f1f71bc2b0d9 147 Pfam PF14242 Domain of unknown function (DUF4342) 53 117 9.0E-16 T 13-10-2018 IPR025642 Domain of unknown function DUF4342 CLOST_2263 175d656286996dfee826f1f71bc2b0d9 147 Gene3D G3DSA:1.10.8.10 1 50 2.6E-7 T 13-10-2018 CLOST_2263 175d656286996dfee826f1f71bc2b0d9 147 SUPERFAMILY SSF46934 1 48 6.43E-12 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 CLOST_1015 f57f63b46a1a8adb55ba649a12f27a57 290 Gene3D G3DSA:3.40.50.620 25 274 1.2E-45 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1015 f57f63b46a1a8adb55ba649a12f27a57 290 Pfam PF01171 PP-loop family 56 218 3.6E-15 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CLOST_1015 f57f63b46a1a8adb55ba649a12f27a57 290 PIRSF PIRSF004976 3 290 1.9E-66 T 13-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 CLOST_1015 f57f63b46a1a8adb55ba649a12f27a57 290 SUPERFAMILY SSF52402 32 245 4.85E-43 T 13-10-2018 CLOST_2098 98768de2ac4761d3cb0f783835d2f74a 190 Pfam PF09819 ABC-type cobalt transport system, permease component 21 140 1.2E-11 T 13-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CLOST_2387 5101c1c95d462e55fdd7bbed3d86a23d 368 Pfam PF01594 AI-2E family transporter 8 346 2.1E-58 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like CLOST_0226 dbc1813c3a06b607f4d6267126abc01d 294 SUPERFAMILY SSF82549 1 281 5.23E-81 T 13-10-2018 CLOST_0226 dbc1813c3a06b607f4d6267126abc01d 294 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 2.9E-82 T 13-10-2018 IPR003797 DegV CLOST_0226 dbc1813c3a06b607f4d6267126abc01d 294 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 280 8.8E-87 T 13-10-2018 IPR003797 DegV CLOST_0226 dbc1813c3a06b607f4d6267126abc01d 294 Gene3D G3DSA:3.40.50.10170 1 153 8.2E-50 T 13-10-2018 CLOST_0226 dbc1813c3a06b607f4d6267126abc01d 294 Gene3D G3DSA:3.30.1180.10 154 282 1.8E-33 T 13-10-2018 CLOST_0731 9f49fb7192248e20a707d9fdd0652f58 304 Pfam PF04055 Radical SAM superfamily 31 198 6.2E-14 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0731 9f49fb7192248e20a707d9fdd0652f58 304 Gene3D G3DSA:3.80.30.30 63 279 7.8E-9 T 13-10-2018 CLOST_0731 9f49fb7192248e20a707d9fdd0652f58 304 SMART SM00729 26 252 7.8E-4 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0731 9f49fb7192248e20a707d9fdd0652f58 304 SUPERFAMILY SSF102114 31 214 7.72E-13 T 13-10-2018 CLOST_2046 0448a3254d7adb829b91aa932af0fed1 428 Pfam PF12844 Helix-turn-helix domain 10 72 7.4E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2046 0448a3254d7adb829b91aa932af0fed1 428 SUPERFAMILY SSF47413 8 58 9.57E-7 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_2046 0448a3254d7adb829b91aa932af0fed1 428 Gene3D G3DSA:1.10.260.40 8 75 2.6E-6 T 13-10-2018 CLOST_2046 0448a3254d7adb829b91aa932af0fed1 428 SUPERFAMILY SSF48452 207 366 3.21E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0549 4253818c0823e0e5749c14fb32808812 318 Gene3D G3DSA:3.30.420.40 129 301 5.7E-95 T 13-10-2018 CLOST_0549 4253818c0823e0e5749c14fb32808812 318 Gene3D G3DSA:3.30.420.40 6 314 5.7E-95 T 13-10-2018 CLOST_0549 4253818c0823e0e5749c14fb32808812 318 Pfam PF00480 ROK family 5 314 1.1E-74 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CLOST_0549 4253818c0823e0e5749c14fb32808812 318 SUPERFAMILY SSF53067 5 316 1.36E-67 T 13-10-2018 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 Gene3D G3DSA:3.40.50.720 213 434 3.5E-65 T 13-10-2018 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 PIRSF PIRSF500136 4 436 7.8E-164 T 13-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 SUPERFAMILY SSF52413 316 426 6.8E-26 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 331 426 3.0E-20 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 Gene3D G3DSA:3.40.50.720 1 210 2.5E-68 T 13-10-2018 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 SMART SM00984 331 427 2.6E-25 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 PIRSF PIRSF000124 14 433 1.3E-69 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 SUPERFAMILY SSF51735 15 205 5.12E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 SUPERFAMILY SSF48179 213 306 9.18E-31 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 214 304 7.4E-30 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 15 423 1.3E-135 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CLOST_2337 43f39f884d18db48f36e175fbbcc7c9d 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 15 192 7.0E-44 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CLOST_1531 4287998c50c591da9b13c8662144452b 429 Gene3D G3DSA:3.40.50.300 29 231 2.7E-28 T 13-10-2018 CLOST_1531 4287998c50c591da9b13c8662144452b 429 Pfam PF03237 Terminase-like family 40 239 8.6E-10 T 13-10-2018 IPR004921 Terminase large subunit, T4likevirus-type CLOST_1531 4287998c50c591da9b13c8662144452b 429 Gene3D G3DSA:3.30.420.280 237 414 1.8E-35 T 13-10-2018 CLOST_1531 4287998c50c591da9b13c8662144452b 429 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 36 413 2.7E-73 T 13-10-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 CLOST_0342 57d18857ad11e3c27c8875866444555a 102 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.9E-10 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOST_0342 57d18857ad11e3c27c8875866444555a 102 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.9E-10 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOST_0342 57d18857ad11e3c27c8875866444555a 102 SUPERFAMILY SSF47729 1 94 2.36E-29 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 CLOST_0342 57d18857ad11e3c27c8875866444555a 102 Pfam PF00216 Bacterial DNA-binding protein 1 91 1.9E-31 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOST_0342 57d18857ad11e3c27c8875866444555a 102 Gene3D G3DSA:4.10.520.10 1 100 5.6E-35 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 CLOST_0342 57d18857ad11e3c27c8875866444555a 102 SMART SM00411 1 91 7.1E-38 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CLOST_0422 025a9d6343fbb81150fbaae2a8831594 382 PRINTS PR00164 ABC-2 type transport system membrane protein signature 286 305 3.1E-5 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_0422 025a9d6343fbb81150fbaae2a8831594 382 PRINTS PR00164 ABC-2 type transport system membrane protein signature 174 196 3.1E-5 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_0422 025a9d6343fbb81150fbaae2a8831594 382 PRINTS PR00164 ABC-2 type transport system membrane protein signature 248 272 3.1E-5 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_0422 025a9d6343fbb81150fbaae2a8831594 382 PRINTS PR00164 ABC-2 type transport system membrane protein signature 306 325 3.1E-5 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CLOST_0422 025a9d6343fbb81150fbaae2a8831594 382 Pfam PF12698 ABC-2 family transporter protein 9 356 1.0E-33 T 13-10-2018 CLOST_1141 807d31314777356e25ea1ed446641a23 261 Pfam PF00588 SpoU rRNA Methylase family 114 253 2.1E-33 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CLOST_1141 807d31314777356e25ea1ed446641a23 261 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 100 3.5E-7 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CLOST_1141 807d31314777356e25ea1ed446641a23 261 SUPERFAMILY SSF55315 3 100 1.41E-19 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like CLOST_1141 807d31314777356e25ea1ed446641a23 261 SMART SM00967 31 104 2.4E-6 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CLOST_1141 807d31314777356e25ea1ed446641a23 261 Gene3D G3DSA:3.30.1330.30 8 104 2.7E-18 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like CLOST_1141 807d31314777356e25ea1ed446641a23 261 Gene3D G3DSA:3.40.1280.10 105 260 9.2E-49 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CLOST_1141 807d31314777356e25ea1ed446641a23 261 SUPERFAMILY SSF75217 100 256 1.44E-37 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases CLOST_1589 305513637dfe16d907e92b4a886a49c2 144 Pfam PF00692 dUTPase 27 140 2.9E-12 T 13-10-2018 IPR029054 dUTPase-like CLOST_1589 305513637dfe16d907e92b4a886a49c2 144 SUPERFAMILY SSF51283 5 143 1.83E-24 T 13-10-2018 IPR036157 dUTPase-like superfamily CLOST_1589 305513637dfe16d907e92b4a886a49c2 144 Gene3D G3DSA:2.70.40.10 1 144 1.8E-35 T 13-10-2018 IPR036157 dUTPase-like superfamily CLOST_0455 80602caf92bdefb9b38a3b60dc3ea062 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 1.5E-17 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_0455 80602caf92bdefb9b38a3b60dc3ea062 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.6E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_0455 80602caf92bdefb9b38a3b60dc3ea062 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.6E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CLOST_0455 80602caf92bdefb9b38a3b60dc3ea062 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CLOST_0455 80602caf92bdefb9b38a3b60dc3ea062 204 SUPERFAMILY SSF46689 3 69 9.75E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CLOST_0455 80602caf92bdefb9b38a3b60dc3ea062 204 SUPERFAMILY SSF48498 89 202 1.42E-12 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily CLOST_0455 80602caf92bdefb9b38a3b60dc3ea062 204 Gene3D G3DSA:1.10.357.10 1 200 4.5E-42 T 13-10-2018 CLOST_2101 ee609651b47c6b25d9136b8294a37b24 532 Pfam PF04205 FMN-binding domain 90 178 7.9E-14 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOST_2101 ee609651b47c6b25d9136b8294a37b24 532 SMART SM00900 90 181 1.1E-16 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOST_2101 ee609651b47c6b25d9136b8294a37b24 532 SUPERFAMILY SSF56524 216 338 5.76E-16 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 CLOST_2101 ee609651b47c6b25d9136b8294a37b24 532 Pfam PF00174 Oxidoreductase molybdopterin binding domain 241 338 7.3E-11 T 13-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CLOST_2101 ee609651b47c6b25d9136b8294a37b24 532 Gene3D G3DSA:3.90.420.10 229 349 1.5E-8 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 CLOST_0914 5ba0dd5dafb9e3c68542b20b77ab3a10 268 Pfam PF12640 UPF0489 domain 79 187 3.1E-10 T 13-10-2018 IPR024131 Uncharacterised protein family UPF0489 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 SUPERFAMILY SSF144052 1 406 6.93E-145 T 13-10-2018 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 Gene3D G3DSA:3.40.1830.10 1 177 1.5E-67 T 13-10-2018 IPR035097 Peptidase M29, N-terminal CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 242 261 6.0E-63 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 298 318 6.0E-63 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 360 382 6.0E-63 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 321 342 6.0E-63 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 386 405 6.0E-63 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 12 29 6.0E-63 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 77 96 6.0E-63 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 153 175 6.0E-63 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_0864 a027c7b911dbb772f55b884bb1b47597 407 Pfam PF02073 Thermophilic metalloprotease (M29) 2 405 9.8E-176 T 13-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CLOST_1903 c533b4fd147069f623b0555dd948f85a 249 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 2 236 2.3E-62 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 CLOST_1903 c533b4fd147069f623b0555dd948f85a 249 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 129 141 - T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 CLOST_1903 c533b4fd147069f623b0555dd948f85a 249 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 234 5.0E-79 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 CLOST_1903 c533b4fd147069f623b0555dd948f85a 249 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 241 16.96 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 CLOST_1383 085946da0dd391e1e730bb881d410b78 344 SUPERFAMILY SSF51735 180 308 1.63E-13 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1383 085946da0dd391e1e730bb881d410b78 344 Gene3D G3DSA:3.90.180.10 30 343 1.4E-16 T 13-10-2018 CLOST_0756 73bbd56182730068b2ad27d607926f3f 299 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 91 213 1.7E-17 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CLOST_0756 73bbd56182730068b2ad27d607926f3f 299 SUPERFAMILY SSF52518 6 295 8.32E-57 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_0756 73bbd56182730068b2ad27d607926f3f 299 Gene3D G3DSA:3.40.50.970 71 299 4.6E-53 T 13-10-2018 CLOST_0877 35e0a7d1554c0c5a2a74b31af2ee23f5 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 431 1.3E-75 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain CLOST_0877 35e0a7d1554c0c5a2a74b31af2ee23f5 536 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 86 108 - T 13-10-2018 IPR023765 Solute-binding protein family 5, conserved site CLOST_0877 35e0a7d1554c0c5a2a74b31af2ee23f5 536 Gene3D G3DSA:3.10.105.10 260 507 5.0E-187 T 13-10-2018 CLOST_0877 35e0a7d1554c0c5a2a74b31af2ee23f5 536 SUPERFAMILY SSF53850 38 534 4.89E-103 T 13-10-2018 CLOST_0877 35e0a7d1554c0c5a2a74b31af2ee23f5 536 Gene3D G3DSA:3.40.190.10 53 519 5.0E-187 T 13-10-2018 CLOST_0877 35e0a7d1554c0c5a2a74b31af2ee23f5 536 PIRSF PIRSF002741 1 525 1.7E-87 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CLOST_2305 b5c6163363ec03ac74b6d18f8fe5669f 162 Pfam PF02561 Flagellar protein FliS 9 115 5.1E-16 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 CLOST_2305 b5c6163363ec03ac74b6d18f8fe5669f 162 Gene3D G3DSA:1.20.120.340 1 118 4.2E-15 T 13-10-2018 CLOST_2305 b5c6163363ec03ac74b6d18f8fe5669f 162 SUPERFAMILY SSF101116 5 115 2.35E-15 T 13-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 CLOST_0841 7f6ada0861b596affe01ebf566d5ee97 196 Gene3D G3DSA:3.90.550.10 3 195 3.4E-43 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0841 7f6ada0861b596affe01ebf566d5ee97 196 SUPERFAMILY SSF53448 6 190 1.31E-24 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0841 7f6ada0861b596affe01ebf566d5ee97 196 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 3 192 23.356 T 13-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CLOST_0841 7f6ada0861b596affe01ebf566d5ee97 196 Pfam PF12804 MobA-like NTP transferase domain 7 157 3.1E-23 T 13-10-2018 IPR025877 MobA-like NTP transferase CLOST_0326 3d27df3f62f577a2e9efac955f9888e2 269 SMART SM00849 21 241 0.004 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0326 3d27df3f62f577a2e9efac955f9888e2 269 Pfam PF00753 Metallo-beta-lactamase superfamily 21 91 9.3E-13 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_0326 3d27df3f62f577a2e9efac955f9888e2 269 SUPERFAMILY SSF56281 4 244 5.24E-29 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_0326 3d27df3f62f577a2e9efac955f9888e2 269 Gene3D G3DSA:3.60.15.10 1 266 1.1E-71 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1624 bf75e7673d912a4d5fd6e64a4df5d080 143 Pfam PF01047 MarR family 35 91 1.1E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1624 bf75e7673d912a4d5fd6e64a4df5d080 143 SMART SM00347 27 127 1.3E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1624 bf75e7673d912a4d5fd6e64a4df5d080 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 2.0E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1624 bf75e7673d912a4d5fd6e64a4df5d080 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 2.0E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1624 bf75e7673d912a4d5fd6e64a4df5d080 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 2.0E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1624 bf75e7673d912a4d5fd6e64a4df5d080 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 2.0E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1624 bf75e7673d912a4d5fd6e64a4df5d080 143 SUPERFAMILY SSF46785 6 141 3.59E-32 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1624 bf75e7673d912a4d5fd6e64a4df5d080 143 Gene3D G3DSA:1.10.10.10 5 135 1.9E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2436 12c348ed04bbb0fb0cb7b5423dfce313 312 SMART SM00283 51 309 1.1E-45 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2436 12c348ed04bbb0fb0cb7b5423dfce313 312 SUPERFAMILY SSF58104 34 301 4.12E-56 T 13-10-2018 CLOST_2436 12c348ed04bbb0fb0cb7b5423dfce313 312 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 97 269 1.6E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_2436 12c348ed04bbb0fb0cb7b5423dfce313 312 Gene3D G3DSA:1.10.287.950 13 312 1.1E-59 T 13-10-2018 CLOST_0611 af5a240b15954050b21eab00249aa28b 332 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 314 6.4E-70 T 13-10-2018 IPR011862 Phosphate binding protein GO:0042301 CLOST_0611 af5a240b15954050b21eab00249aa28b 332 Gene3D G3DSA:3.40.190.10 129 274 6.3E-65 T 13-10-2018 CLOST_0611 af5a240b15954050b21eab00249aa28b 332 SUPERFAMILY SSF53850 42 328 1.94E-61 T 13-10-2018 CLOST_0611 af5a240b15954050b21eab00249aa28b 332 Pfam PF12849 PBP superfamily domain 37 268 1.2E-23 T 13-10-2018 IPR024370 PBP domain CLOST_0611 af5a240b15954050b21eab00249aa28b 332 Gene3D G3DSA:3.40.190.10 45 304 6.3E-65 T 13-10-2018 CLOST_2381 25274929456764900546e118fac481e8 120 Gene3D G3DSA:3.40.50.2300 1 119 2.3E-23 T 13-10-2018 CLOST_2381 25274929456764900546e118fac481e8 120 SUPERFAMILY SSF52172 1 117 3.98E-23 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_2381 25274929456764900546e118fac481e8 120 SMART SM00448 1 114 1.7E-12 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_2381 25274929456764900546e118fac481e8 120 Pfam PF00072 Response regulator receiver domain 3 114 4.7E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 17 44 1.0E-7 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 Gene3D G3DSA:1.20.5.1150 17 57 1.6E-17 T 13-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 PRINTS PR00976 Ribosomal protein S21 family signature 38 48 1.1E-13 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 PRINTS PR00976 Ribosomal protein S21 family signature 26 36 1.1E-13 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 PRINTS PR00976 Ribosomal protein S21 family signature 6 14 1.1E-13 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 PRINTS PR00976 Ribosomal protein S21 family signature 14 23 1.1E-13 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 Pfam PF01165 Ribosomal protein S21 4 58 2.7E-22 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 4 57 6.2E-22 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1787 2ed9882419ce15ddcd728460d467a08b 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 2 58 20.291 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_0025 195d271e30b6e0d07d111ee7307e7956 275 Pfam PF02517 CAAX protease self-immunity 139 224 4.2E-18 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CLOST_0389 18bb3e52323720f82cf5bc82f9fc8f42 700 Gene3D G3DSA:1.25.40.10 399 595 1.1E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2412 6179aa643070227bef038b7b64975e9b 495 SMART SM00382 30 219 5.5E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2412 6179aa643070227bef038b7b64975e9b 495 SMART SM00382 277 478 4.4E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2412 6179aa643070227bef038b7b64975e9b 495 Gene3D G3DSA:3.40.50.300 258 489 1.4E-42 T 13-10-2018 CLOST_2412 6179aa643070227bef038b7b64975e9b 495 Pfam PF00005 ABC transporter 21 169 5.3E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2412 6179aa643070227bef038b7b64975e9b 495 Gene3D G3DSA:3.40.50.300 1 246 4.3E-61 T 13-10-2018 CLOST_2412 6179aa643070227bef038b7b64975e9b 495 SUPERFAMILY SSF52540 266 481 1.23E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2412 6179aa643070227bef038b7b64975e9b 495 Pfam PF00005 ABC transporter 269 422 9.9E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2412 6179aa643070227bef038b7b64975e9b 495 SUPERFAMILY SSF52540 4 228 1.41E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2412 6179aa643070227bef038b7b64975e9b 495 ProSitePatterns PS00211 ABC transporters family signature. 395 409 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1035 5292e83d830552fe5bbb602e351213fe 440 SUPERFAMILY SSF52540 6 366 2.74E-17 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1035 5292e83d830552fe5bbb602e351213fe 440 Gene3D G3DSA:3.40.50.300 236 378 1.3E-10 T 13-10-2018 CLOST_1035 5292e83d830552fe5bbb602e351213fe 440 Gene3D G3DSA:3.40.50.300 6 140 2.8E-5 T 13-10-2018 CLOST_1035 5292e83d830552fe5bbb602e351213fe 440 Pfam PF13175 AAA ATPase domain 244 357 1.7E-15 T 13-10-2018 CLOST_1035 5292e83d830552fe5bbb602e351213fe 440 Pfam PF13175 AAA ATPase domain 6 159 9.4E-12 T 13-10-2018 CLOST_0162 7f2f7b6728158ca1afb9c730a39c7323 128 SUPERFAMILY SSF101386 80 118 6.73E-6 T 13-10-2018 CLOST_2149 710a089e9d59be52a03e5245c62e9014 425 Gene3D G3DSA:3.90.1150.10 290 425 3.0E-49 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_2149 710a089e9d59be52a03e5245c62e9014 425 SUPERFAMILY SSF53383 5 422 8.53E-111 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_2149 710a089e9d59be52a03e5245c62e9014 425 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 6 422 2.1E-178 T 13-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CLOST_2149 710a089e9d59be52a03e5245c62e9014 425 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 422 9.8E-127 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CLOST_2149 710a089e9d59be52a03e5245c62e9014 425 Gene3D G3DSA:3.40.640.10 2 286 9.2E-89 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_2149 710a089e9d59be52a03e5245c62e9014 425 PIRSF PIRSF001434 1 424 6.5E-123 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CLOST_0114 d0ed1c26497c084d912c06960053071f 232 Gene3D G3DSA:2.60.120.10 9 229 4.9E-77 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0114 d0ed1c26497c084d912c06960053071f 232 Gene3D G3DSA:2.60.120.10 11 134 4.9E-77 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0114 d0ed1c26497c084d912c06960053071f 232 Pfam PF02678 Pirin 15 118 2.9E-32 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CLOST_0114 d0ed1c26497c084d912c06960053071f 232 SUPERFAMILY SSF51182 2 230 6.08E-66 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0114 d0ed1c26497c084d912c06960053071f 232 PIRSF PIRSF006232 1 231 5.6E-54 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CLOST_0923 02d9d9d2e8b7255df2b99426ed0b9919 306 Gene3D G3DSA:3.40.1790.10 1 305 7.4E-96 T 13-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CLOST_0923 02d9d9d2e8b7255df2b99426ed0b9919 306 SUPERFAMILY SSF110581 2 300 9.42E-81 T 13-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CLOST_0923 02d9d9d2e8b7255df2b99426ed0b9919 306 Pfam PF04227 Indigoidine synthase A like protein 12 297 5.5E-97 T 13-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CLOST_0359 5343417e54055efae0588ac4605e9e7f 204 Pfam PF02397 Bacterial sugar transferase 23 198 4.5E-60 T 13-10-2018 IPR003362 Bacterial sugar transferase CLOST_2161 85e267da674106f5a20c026e28fe465b 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.085 T 13-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CLOST_2161 85e267da674106f5a20c026e28fe465b 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 13-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CLOST_2161 85e267da674106f5a20c026e28fe465b 130 SUPERFAMILY SSF54211 6 130 1.18E-48 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CLOST_2161 85e267da674106f5a20c026e28fe465b 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 3.8E-48 T 13-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CLOST_2161 85e267da674106f5a20c026e28fe465b 130 Gene3D G3DSA:3.30.230.10 1 130 7.1E-54 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CLOST_2036 b322d6605be808959e771ae5cd0504de 148 Gene3D G3DSA:3.40.630.30 1 146 5.0E-26 T 13-10-2018 CLOST_2036 b322d6605be808959e771ae5cd0504de 148 SUPERFAMILY SSF55729 1 141 7.15E-25 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2036 b322d6605be808959e771ae5cd0504de 148 Pfam PF00583 Acetyltransferase (GNAT) family 32 135 6.3E-15 T 13-10-2018 IPR000182 GNAT domain CLOST_1711 b9138895ef32e5a334ac71e97d9effcf 161 Gene3D G3DSA:3.30.1330.200 2 161 1.1E-50 T 13-10-2018 IPR038592 CheD-like superfamily CLOST_1711 b9138895ef32e5a334ac71e97d9effcf 161 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 157 26.286 T 13-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CLOST_1711 b9138895ef32e5a334ac71e97d9effcf 161 SUPERFAMILY SSF64438 5 159 1.19E-46 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CLOST_1711 b9138895ef32e5a334ac71e97d9effcf 161 Pfam PF03975 CheD chemotactic sensory transduction 48 152 4.9E-34 T 13-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CLOST_0804 56f5a044f29b3c885b2ccb6153430359 385 SUPERFAMILY SSF51338 2 384 5.41E-27 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0804 56f5a044f29b3c885b2ccb6153430359 385 Gene3D G3DSA:2.30.40.10 4 379 1.4E-134 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0804 56f5a044f29b3c885b2ccb6153430359 385 Pfam PF01979 Amidohydrolase family 51 382 8.8E-24 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CLOST_0804 56f5a044f29b3c885b2ccb6153430359 385 Gene3D G3DSA:3.20.20.140 55 345 1.4E-134 T 13-10-2018 CLOST_0804 56f5a044f29b3c885b2ccb6153430359 385 SUPERFAMILY SSF51556 54 349 2.44E-51 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_0429 31981ff09d152f27140b95805c10e0ed 485 SUPERFAMILY SSF53383 26 482 1.51E-106 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0429 31981ff09d152f27140b95805c10e0ed 485 Gene3D G3DSA:3.40.640.10 84 317 7.0E-61 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0429 31981ff09d152f27140b95805c10e0ed 485 Gene3D G3DSA:3.90.1150.10 336 468 6.0E-45 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0429 31981ff09d152f27140b95805c10e0ed 485 Pfam PF02347 Glycine cleavage system P-protein 29 298 4.6E-11 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CLOST_0429 31981ff09d152f27140b95805c10e0ed 485 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 5 483 57.435 T 13-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CLOST_1390 4f31b6195e15dcb48ea13a4ee2724a4c 99 Gene3D G3DSA:3.40.50.300 1 99 2.9E-28 T 13-10-2018 CLOST_1390 4f31b6195e15dcb48ea13a4ee2724a4c 99 SUPERFAMILY SSF52540 1 89 7.7E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1390 4f31b6195e15dcb48ea13a4ee2724a4c 99 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 57 7.9E-16 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOST_1724 29955e6e05b66dc91a87fc94bf2c3255 93 Pfam PF04347 Flagellar biosynthesis protein, FliO 33 87 2.4E-7 T 13-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CLOST_0559 d19df12304814a7439d4480b5bfa75bb 415 SMART SM01043 114 260 4.7E-6 T 13-10-2018 IPR005158 Bacterial transcriptional activator domain CLOST_0559 d19df12304814a7439d4480b5bfa75bb 415 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 87 1.2E-4 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CLOST_0559 d19df12304814a7439d4480b5bfa75bb 415 SUPERFAMILY SSF46894 9 88 3.4E-7 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CLOST_0559 d19df12304814a7439d4480b5bfa75bb 415 Gene3D G3DSA:1.25.40.10 114 283 2.1E-19 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0559 d19df12304814a7439d4480b5bfa75bb 415 Gene3D G3DSA:1.10.10.10 2 108 1.4E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0559 d19df12304814a7439d4480b5bfa75bb 415 SUPERFAMILY SSF48452 140 263 5.82E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_0559 d19df12304814a7439d4480b5bfa75bb 415 Pfam PF03704 Bacterial transcriptional activator domain 114 260 1.6E-16 T 13-10-2018 IPR005158 Bacterial transcriptional activator domain CLOST_1144 b22dc0bdf36b5696ce9092e6cfd4fac5 167 SUPERFAMILY SSF102829 3 89 1.83E-14 T 13-10-2018 IPR036192 Cell division protein ZapA-like superfamily CLOST_1144 b22dc0bdf36b5696ce9092e6cfd4fac5 167 Pfam PF05164 Cell division protein ZapA 4 85 6.6E-14 T 13-10-2018 IPR007838 Cell division protein ZapA-like CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 Hamap MF_00625 Selenide, water dikinase [selD]. 2 324 37.025 T 13-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 SUPERFAMILY SSF56042 136 321 1.64E-50 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 SUPERFAMILY SSF55326 3 134 1.94E-37 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 Gene3D G3DSA:3.30.1330.10 1 136 3.2E-40 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 TIGRFAM TIGR00476 selD: selenide, water dikinase 1 291 3.5E-109 T 13-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 Gene3D G3DSA:3.90.650.10 137 321 6.0E-53 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 Pfam PF00586 AIR synthase related protein, N-terminal domain 24 129 1.5E-18 T 13-10-2018 IPR016188 PurM-like, N-terminal domain CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 Pfam PF02769 AIR synthase related protein, C-terminal domain 142 322 5.2E-29 T 13-10-2018 IPR010918 PurM-like, C-terminal domain CLOST_1359 ffe360bd71ac1c3d262ab3f89acb3724 324 PIRSF PIRSF036407 1 324 2.4E-114 T 13-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CLOST_2572 7385df3bf7276e1092ed4fb70e9352cf 66 PIRSF PIRSF037263 1 65 1.9E-25 T 13-10-2018 IPR009296 Protein of unknown function DUF951 CLOST_2572 7385df3bf7276e1092ed4fb70e9352cf 66 Pfam PF06107 Bacterial protein of unknown function (DUF951) 5 59 1.8E-25 T 13-10-2018 IPR009296 Protein of unknown function DUF951 CLOST_1757 ac4cc68bade46b7856cf77ef0ca105fa 257 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 21 253 6.2E-110 T 13-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CLOST_1757 ac4cc68bade46b7856cf77ef0ca105fa 257 Gene3D G3DSA:3.20.20.70 9 257 6.0E-94 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1757 ac4cc68bade46b7856cf77ef0ca105fa 257 SUPERFAMILY SSF51569 21 253 7.05E-90 T 13-10-2018 CLOST_1757 ac4cc68bade46b7856cf77ef0ca105fa 257 Pfam PF00793 DAHP synthetase I family 23 250 9.9E-73 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CLOST_2054 08a637e619043d60102346956c8556f2 102 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 3 89 3.2E-16 T 13-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 CLOST_1958 054e5c8cd18c11a4343b77facbc3fee5 306 Pfam PF12146 Serine aminopeptidase, S33 25 289 3.4E-49 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 CLOST_1958 054e5c8cd18c11a4343b77facbc3fee5 306 SUPERFAMILY SSF53474 3 304 3.48E-36 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold CLOST_1958 054e5c8cd18c11a4343b77facbc3fee5 306 Gene3D G3DSA:3.40.50.1820 1 306 5.9E-50 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold CLOST_0201 fa076cb68731ad5146b0812bd62adc49 320 Gene3D G3DSA:3.40.50.360 1 231 4.7E-33 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0201 fa076cb68731ad5146b0812bd62adc49 320 SUPERFAMILY SSF52218 1 223 1.4E-32 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0201 fa076cb68731ad5146b0812bd62adc49 320 Pfam PF03358 NADPH-dependent FMN reductase 1 176 5.3E-22 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CLOST_0135 2d60d395a60fce5433ae492db58ab154 173 SUPERFAMILY SSF55729 5 164 6.45E-28 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0135 2d60d395a60fce5433ae492db58ab154 173 Gene3D G3DSA:3.40.630.30 4 172 1.5E-30 T 13-10-2018 CLOST_0135 2d60d395a60fce5433ae492db58ab154 173 Pfam PF13302 Acetyltransferase (GNAT) domain 15 138 9.7E-7 T 13-10-2018 IPR000182 GNAT domain CLOST_0624 cd9852ee879352fba8e8c5e3f7fd9869 86 TIGRFAM TIGR03905 TIGR03905_4_Cys: uncharacterized protein TIGR03905 3 77 4.0E-34 T 13-10-2018 IPR023806 Conserved hypothetical protein CHP03905 CLOST_0624 cd9852ee879352fba8e8c5e3f7fd9869 86 Pfam PF12637 TSCPD domain 4 77 3.9E-33 T 13-10-2018 IPR024434 TSCPD domain CLOST_0458 70e71cd1d06cbe4fa0b8eed83953f22b 71 Pfam PF11148 Protein of unknown function (DUF2922) 4 68 4.1E-14 T 13-10-2018 IPR021321 Protein of unknown function DUF2922 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 5.2E-54 T 13-10-2018 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 PRINTS PR00173 Glutamate-aspartate symporter signature 53 73 5.2E-54 T 13-10-2018 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 5.2E-54 T 13-10-2018 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 PRINTS PR00173 Glutamate-aspartate symporter signature 359 379 5.2E-54 T 13-10-2018 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 5.2E-54 T 13-10-2018 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 PRINTS PR00173 Glutamate-aspartate symporter signature 83 108 5.2E-54 T 13-10-2018 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 5.2E-54 T 13-10-2018 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 SUPERFAMILY SSF118215 6 405 3.79E-122 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 Pfam PF00375 Sodium:dicarboxylate symporter family 6 404 1.3E-133 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CLOST_0604 bd3af47af90ec28adb36eed01ddb33bd 426 Gene3D G3DSA:1.10.3860.10 1 423 3.3E-142 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 CLOST_1851 2360f6d2ee23820b9b48905ecf932044 341 Gene3D G3DSA:3.20.20.70 66 326 1.2E-96 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1851 2360f6d2ee23820b9b48905ecf932044 341 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 2 338 1.2E-116 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 CLOST_1851 2360f6d2ee23820b9b48905ecf932044 341 PIRSF PIRSF006004 1 341 5.3E-122 T 13-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 CLOST_1851 2360f6d2ee23820b9b48905ecf932044 341 Pfam PF04055 Radical SAM superfamily 106 266 7.6E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1851 2360f6d2ee23820b9b48905ecf932044 341 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 2 341 66.693 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 CLOST_1851 2360f6d2ee23820b9b48905ecf932044 341 SUPERFAMILY SSF102114 99 291 9.16E-11 T 13-10-2018 CLOST_1851 2360f6d2ee23820b9b48905ecf932044 341 Gene3D G3DSA:1.10.150.530 2 62 1.2E-11 T 13-10-2018 CLOST_0773 d2557b1e08753e719ba3d444d9b3c14f 331 Pfam PF13407 Periplasmic binding protein domain 46 300 1.7E-52 T 13-10-2018 IPR025997 Periplasmic binding protein CLOST_0773 d2557b1e08753e719ba3d444d9b3c14f 331 Gene3D G3DSA:3.40.50.2300 145 318 8.9E-65 T 13-10-2018 CLOST_0773 d2557b1e08753e719ba3d444d9b3c14f 331 Gene3D G3DSA:3.40.50.2300 43 310 8.9E-65 T 13-10-2018 CLOST_0773 d2557b1e08753e719ba3d444d9b3c14f 331 SUPERFAMILY SSF53822 41 321 1.46E-63 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_0157 193854327a43f98134510c79c034b2f1 123 Gene3D G3DSA:3.10.180.10 1 123 3.7E-26 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOST_0157 193854327a43f98134510c79c034b2f1 123 SUPERFAMILY SSF54593 4 119 2.95E-26 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOST_0157 193854327a43f98134510c79c034b2f1 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 118 5.0E-11 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CLOST_0872 c8cfbc365aba138cbf2d9828bc68dee3 302 SUPERFAMILY SSF53850 51 281 2.27E-28 T 13-10-2018 CLOST_0872 c8cfbc365aba138cbf2d9828bc68dee3 302 Pfam PF12849 PBP superfamily domain 45 269 6.5E-30 T 13-10-2018 IPR024370 PBP domain CLOST_0872 c8cfbc365aba138cbf2d9828bc68dee3 302 Gene3D G3DSA:3.40.190.10 53 277 1.9E-92 T 13-10-2018 CLOST_0872 c8cfbc365aba138cbf2d9828bc68dee3 302 Gene3D G3DSA:3.40.190.10 128 240 1.9E-92 T 13-10-2018 CLOST_2127 473f879c2734b67c2b0bb1ed47f2eac9 162 Gene3D G3DSA:3.40.140.10 1 149 6.4E-30 T 13-10-2018 CLOST_2127 473f879c2734b67c2b0bb1ed47f2eac9 162 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 7 134 4.3E-17 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CLOST_2127 473f879c2734b67c2b0bb1ed47f2eac9 162 SUPERFAMILY SSF53927 7 137 4.63E-24 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CLOST_2127 473f879c2734b67c2b0bb1ed47f2eac9 162 PIRSF PIRSF006019 1 159 4.2E-32 T 13-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CLOST_1716 bbef07f18e4f90735dab1bd25d8524ee 213 Gene3D G3DSA:2.40.10.220 103 206 1.8E-9 T 13-10-2018 CLOST_1716 bbef07f18e4f90735dab1bd25d8524ee 213 Pfam PF12945 Flagellar protein YcgR 9 93 2.6E-14 T 13-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal CLOST_1716 bbef07f18e4f90735dab1bd25d8524ee 213 Pfam PF07238 PilZ domain 102 202 1.6E-17 T 13-10-2018 IPR009875 PilZ domain GO:0035438 CLOST_1716 bbef07f18e4f90735dab1bd25d8524ee 213 SUPERFAMILY SSF141371 102 189 6.28E-6 T 13-10-2018 CLOST_2583 c8c7e1998bbfec493960aca6c7eda7ae 229 Gene3D G3DSA:3.40.50.300 1 229 6.5E-49 T 13-10-2018 CLOST_2583 c8c7e1998bbfec493960aca6c7eda7ae 229 SUPERFAMILY SSF52540 2 215 4.86E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2583 c8c7e1998bbfec493960aca6c7eda7ae 229 SMART SM00382 26 201 3.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2583 c8c7e1998bbfec493960aca6c7eda7ae 229 Pfam PF00005 ABC transporter 17 152 1.8E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2230 d96704ea555dce9ee0cc44e576ab798b 254 TIGRFAM TIGR04482 D_pro_red_PrdD: proline reductase cluster protein PrdD 9 254 1.3E-112 T 13-10-2018 IPR031000 Proline reductase cluster protein PrdD CLOST_2491 bf2ef8872c58da73ebbcc5b6848b3026 164 Pfam PF04525 LURP-one-related 3 147 8.9E-14 T 13-10-2018 IPR007612 LURP-one-related CLOST_2491 bf2ef8872c58da73ebbcc5b6848b3026 164 Gene3D G3DSA:3.20.90.20 1 158 5.4E-9 T 13-10-2018 IPR038595 LURP-one-related superfamily CLOST_2491 bf2ef8872c58da73ebbcc5b6848b3026 164 SUPERFAMILY SSF54518 2 152 1.83E-34 T 13-10-2018 IPR025659 Tubby-like, C-terminal CLOST_2039 c4bc117f6fb471f9700b64848dfa25e0 399 SUPERFAMILY SSF53383 29 397 3.71E-126 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_2039 c4bc117f6fb471f9700b64848dfa25e0 399 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 204 218 - T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CLOST_2039 c4bc117f6fb471f9700b64848dfa25e0 399 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 395 5.5E-151 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CLOST_2039 c4bc117f6fb471f9700b64848dfa25e0 399 PIRSF PIRSF001434 1 399 3.3E-151 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CLOST_2039 c4bc117f6fb471f9700b64848dfa25e0 399 Gene3D G3DSA:3.90.1150.10 264 399 6.4E-55 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_2039 c4bc117f6fb471f9700b64848dfa25e0 399 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 9 396 4.6E-184 T 13-10-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 CLOST_2039 c4bc117f6fb471f9700b64848dfa25e0 399 Gene3D G3DSA:3.40.640.10 10 263 4.0E-99 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_2508 f5d3a42292cc286ff0faf1c28ddaac04 108 Pfam PF08921 Domain of unknown function (DUF1904) 1 107 1.0E-30 T 13-10-2018 IPR015017 Protein of unknown function DUF1904 CLOST_2508 f5d3a42292cc286ff0faf1c28ddaac04 108 Gene3D G3DSA:3.30.429.10 1 108 1.1E-36 T 13-10-2018 IPR014347 Tautomerase/MIF superfamily CLOST_2508 f5d3a42292cc286ff0faf1c28ddaac04 108 SUPERFAMILY SSF55331 1 108 4.67E-27 T 13-10-2018 IPR014347 Tautomerase/MIF superfamily CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 230 1.3E-59 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 Gene3D G3DSA:1.20.1080.10 1 235 3.3E-80 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 PRINTS PR00783 Major intrinsic protein family signature 82 101 2.8E-47 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 PRINTS PR00783 Major intrinsic protein family signature 3 22 2.8E-47 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 PRINTS PR00783 Major intrinsic protein family signature 45 69 2.8E-47 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 PRINTS PR00783 Major intrinsic protein family signature 214 234 2.8E-47 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 PRINTS PR00783 Major intrinsic protein family signature 137 155 2.8E-47 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 PRINTS PR00783 Major intrinsic protein family signature 167 189 2.8E-47 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 Pfam PF00230 Major intrinsic protein 5 231 7.0E-46 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 ProSitePatterns PS00221 MIP family signature. 63 71 - T 13-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 CLOST_1953 1f9ebad55e5a3e2c4f9f02a1b067741d 235 SUPERFAMILY SSF81338 3 234 8.63E-72 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CLOST_0781 d35bd7d5e8b42f9f28b2d84469705b34 195 Gene3D G3DSA:1.20.120.1760 7 194 3.4E-32 T 13-10-2018 CLOST_0781 d35bd7d5e8b42f9f28b2d84469705b34 195 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CLOST_0781 d35bd7d5e8b42f9f28b2d84469705b34 195 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 90 5.3E-11 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CLOST_1461 33f1d8ccbe5a2395d45a9936a462bc73 153 SUPERFAMILY SSF48452 26 131 1.38E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1461 33f1d8ccbe5a2395d45a9936a462bc73 153 Gene3D G3DSA:1.25.40.10 15 139 1.4E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1461 33f1d8ccbe5a2395d45a9936a462bc73 153 Pfam PF13174 Tetratricopeptide repeat 71 94 0.16 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CLOST_1813 b76492fb67f6bdf519e262228eac5f7c 303 SUPERFAMILY SSF52283 1 134 8.32E-30 T 13-10-2018 CLOST_1813 b76492fb67f6bdf519e262228eac5f7c 303 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 276 2.1E-52 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CLOST_1813 b76492fb67f6bdf519e262228eac5f7c 303 Gene3D G3DSA:3.40.50.720 98 279 1.7E-98 T 13-10-2018 CLOST_1813 b76492fb67f6bdf519e262228eac5f7c 303 SUPERFAMILY SSF51735 100 277 6.66E-52 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1813 b76492fb67f6bdf519e262228eac5f7c 303 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 216 232 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CLOST_1813 b76492fb67f6bdf519e262228eac5f7c 303 Gene3D G3DSA:3.40.50.720 4 293 1.7E-98 T 13-10-2018 CLOST_1813 b76492fb67f6bdf519e262228eac5f7c 303 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 292 2.8E-25 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 CLOST_2068 e8b70475fb7df317bbb9c360563ae2e4 212 SUPERFAMILY SSF55021 139 200 7.2E-8 T 13-10-2018 CLOST_2068 e8b70475fb7df317bbb9c360563ae2e4 212 Pfam PF00571 CBS domain 82 128 2.7E-7 T 13-10-2018 IPR000644 CBS domain CLOST_2068 e8b70475fb7df317bbb9c360563ae2e4 212 Pfam PF00571 CBS domain 12 51 1.9E-4 T 13-10-2018 IPR000644 CBS domain CLOST_2068 e8b70475fb7df317bbb9c360563ae2e4 212 SUPERFAMILY SSF54631 1 128 7.96E-22 T 13-10-2018 CLOST_2068 e8b70475fb7df317bbb9c360563ae2e4 212 SMART SM00116 12 59 2.6 T 13-10-2018 IPR000644 CBS domain CLOST_2068 e8b70475fb7df317bbb9c360563ae2e4 212 SMART SM00116 81 129 0.003 T 13-10-2018 IPR000644 CBS domain CLOST_2068 e8b70475fb7df317bbb9c360563ae2e4 212 Gene3D G3DSA:3.10.580.10 1 145 2.1E-22 T 13-10-2018 CLOST_0634 de005c6bd3e0d946d33565e6678c6e37 420 SUPERFAMILY SSF109604 25 156 4.71E-15 T 13-10-2018 CLOST_0634 de005c6bd3e0d946d33565e6678c6e37 420 Pfam PF01966 HD domain 26 124 9.0E-7 T 13-10-2018 IPR006674 HD domain CLOST_0634 de005c6bd3e0d946d33565e6678c6e37 420 Gene3D G3DSA:1.10.3210.10 2 139 1.5E-18 T 13-10-2018 CLOST_0206 1bdd4765d14236208f92cba5e2f68dfa 189 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 186 5.0E-38 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CLOST_0206 1bdd4765d14236208f92cba5e2f68dfa 189 Gene3D G3DSA:3.40.920.10 2 189 1.1E-47 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_0206 1bdd4765d14236208f92cba5e2f68dfa 189 SUPERFAMILY SSF53323 1 188 1.44E-39 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1743 dce8684fd13a88e4a8186d64193ba8f3 146 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 94 143 1.6E-14 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CLOST_1743 dce8684fd13a88e4a8186d64193ba8f3 146 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 146 6.2E-56 T 13-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CLOST_1743 dce8684fd13a88e4a8186d64193ba8f3 146 Pfam PF00460 Flagella basal body rod protein 7 34 5.8E-9 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 Gene3D G3DSA:1.10.3080.10 14 433 1.1E-102 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 SUPERFAMILY SSF116726 438 512 6.67E-11 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 SUPERFAMILY SSF81340 14 430 3.79E-99 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 PRINTS PR00762 Chloride channel signature 114 133 4.5E-34 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 PRINTS PR00762 Chloride channel signature 328 348 4.5E-34 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 PRINTS PR00762 Chloride channel signature 83 100 4.5E-34 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 PRINTS PR00762 Chloride channel signature 165 184 4.5E-34 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 PRINTS PR00762 Chloride channel signature 381 400 4.5E-34 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 Pfam PF00654 Voltage gated chloride channel 72 413 8.1E-86 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 Pfam PF02080 TrkA-C domain 445 511 3.1E-9 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CLOST_2150 29e0564efd920cbc31fb8defafb67f99 519 Gene3D G3DSA:3.30.70.1450 437 515 2.1E-14 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CLOST_0060 1197e96f694543298981ea722ec58e24 237 Gene3D G3DSA:3.30.2010.10 139 231 3.3E-21 T 13-10-2018 CLOST_0060 1197e96f694543298981ea722ec58e24 237 Pfam PF01863 Protein of unknown function DUF45 22 231 1.2E-62 T 13-10-2018 IPR002725 Protein of unknown function DUF45 CLOST_0941 9f3c95b2473e2542b747c2ee8c885c1a 135 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 119 1.4E-24 T 13-10-2018 CLOST_0941 9f3c95b2473e2542b747c2ee8c885c1a 135 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 5 134 1.1E-48 T 13-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 CLOST_0941 9f3c95b2473e2542b747c2ee8c885c1a 135 Gene3D G3DSA:3.10.180.10 1 135 2.1E-44 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOST_0941 9f3c95b2473e2542b747c2ee8c885c1a 135 SUPERFAMILY SSF54593 1 135 8.73E-36 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOST_0525 553cf7493449e672b20185ee8ff8453f 244 SUPERFAMILY SSF51366 1 237 2.02E-54 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CLOST_0525 553cf7493449e672b20185ee8ff8453f 244 Pfam PF00977 Histidine biosynthesis protein 2 230 1.3E-57 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 CLOST_0525 553cf7493449e672b20185ee8ff8453f 244 Gene3D G3DSA:3.20.20.70 1 241 3.2E-71 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0525 553cf7493449e672b20185ee8ff8453f 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 238 30.801 T 13-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CLOST_1152 cfd67e0a1007c122fcce9476b74ab9b4 194 SUPERFAMILY SSF48537 5 160 9.29E-6 T 13-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 CLOST_1152 cfd67e0a1007c122fcce9476b74ab9b4 194 Pfam PF00882 Zinc dependent phospholipase C 5 156 8.4E-24 T 13-10-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 CLOST_0254 4e89fa51dae77f729c15aafe39b5031f 300 Pfam PF06130 Phosphate propanoyltransferase 151 216 1.9E-18 T 13-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 CLOST_0254 4e89fa51dae77f729c15aafe39b5031f 300 Pfam PF06130 Phosphate propanoyltransferase 44 122 1.2E-25 T 13-10-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013 CLOST_0106 46b6fd18016aa7edee446dd6e3909322 400 Pfam PF00999 Sodium/hydrogen exchanger family 8 377 2.4E-43 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CLOST_0106 46b6fd18016aa7edee446dd6e3909322 400 Gene3D G3DSA:1.20.1530.20 1 392 7.8E-33 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily CLOST_0894 383281fef553e05e41270a325b3bb4e5 324 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 178 4.4E-27 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CLOST_0894 383281fef553e05e41270a325b3bb4e5 324 Gene3D G3DSA:3.40.47.10 1 324 1.9E-132 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_0894 383281fef553e05e41270a325b3bb4e5 324 SUPERFAMILY SSF53901 3 323 3.52E-72 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 CLOST_0894 383281fef553e05e41270a325b3bb4e5 324 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 322 68.314 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CLOST_0894 383281fef553e05e41270a325b3bb4e5 324 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 3 322 5.5E-118 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CLOST_0894 383281fef553e05e41270a325b3bb4e5 324 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 233 322 4.8E-37 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CLOST_1760 da77c919f5fd36d180acc86968984afc 266 Gene3D G3DSA:3.20.20.20 1 266 3.4E-110 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1760 da77c919f5fd36d180acc86968984afc 266 Pfam PF00809 Pterin binding enzyme 11 245 3.4E-86 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1760 da77c919f5fd36d180acc86968984afc 266 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 10 259 9.7E-99 T 13-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CLOST_1760 da77c919f5fd36d180acc86968984afc 266 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 44 57 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1760 da77c919f5fd36d180acc86968984afc 266 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 10 25 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1760 da77c919f5fd36d180acc86968984afc 266 SUPERFAMILY SSF51717 4 262 2.35E-99 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0419 5b90e1fcf2f3b2ce52e30717b3aca537 567 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 363 563 1.0E-27 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_0419 5b90e1fcf2f3b2ce52e30717b3aca537 567 SMART SM00331 338 564 2.2E-10 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_0419 5b90e1fcf2f3b2ce52e30717b3aca537 567 Gene3D G3DSA:3.60.40.10 302 565 9.1E-43 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CLOST_0419 5b90e1fcf2f3b2ce52e30717b3aca537 567 Pfam PF17159 Membrane-associated sensor domain 43 271 1.4E-60 T 13-10-2018 IPR033425 Membrane-associated sensor domain MASE3 CLOST_1007 9852d4670471707281d76b970a88a35f 581 Gene3D G3DSA:3.20.20.140 74 315 6.0E-134 T 13-10-2018 CLOST_1007 9852d4670471707281d76b970a88a35f 581 Hamap MF_01518 Adenine deaminase [ade]. 24 575 39.31 T 13-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CLOST_1007 9852d4670471707281d76b970a88a35f 581 TIGRFAM TIGR01178 ade: adenine deaminase 24 575 4.7E-199 T 13-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CLOST_1007 9852d4670471707281d76b970a88a35f 581 Gene3D G3DSA:2.30.40.10 16 352 6.0E-134 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_1007 9852d4670471707281d76b970a88a35f 581 Pfam PF13382 Adenine deaminase C-terminal domain 402 572 4.0E-64 T 13-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CLOST_1007 9852d4670471707281d76b970a88a35f 581 Pfam PF01979 Amidohydrolase family 70 348 4.5E-35 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CLOST_1007 9852d4670471707281d76b970a88a35f 581 SUPERFAMILY SSF51556 74 318 4.99E-37 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_1007 9852d4670471707281d76b970a88a35f 581 SUPERFAMILY SSF51338 19 351 5.71E-19 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CLOST_0487 002116b59afe304114be9472be4af740 301 PIRSF PIRSF000428 1 301 3.3E-85 T 13-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_0487 002116b59afe304114be9472be4af740 301 SUPERFAMILY SSF53659 1 298 1.36E-60 T 13-10-2018 CLOST_0487 002116b59afe304114be9472be4af740 301 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 297 1.2E-124 T 13-10-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 CLOST_0487 002116b59afe304114be9472be4af740 301 Gene3D G3DSA:3.40.718.10 2 299 2.7E-100 T 13-10-2018 CLOST_0487 002116b59afe304114be9472be4af740 301 Pfam PF01515 Phosphate acetyl/butaryl transferase 75 294 2.5E-47 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_0487 002116b59afe304114be9472be4af740 301 Pfam PF01515 Phosphate acetyl/butaryl transferase 4 72 1.9E-7 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CLOST_2576 6381e7758898b3a0dac4ea4502a9dbe0 346 SUPERFAMILY SSF51004 62 202 7.06E-7 T 13-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily CLOST_1030 aa51aab0436829c10248d2be904f4570 236 Gene3D G3DSA:1.10.3290.10 4 229 7.5E-54 T 13-10-2018 IPR036597 Fido-like domain superfamily CLOST_1030 aa51aab0436829c10248d2be904f4570 236 Pfam PF02661 Fic/DOC family 74 172 7.4E-20 T 13-10-2018 IPR003812 Fido domain CLOST_1030 aa51aab0436829c10248d2be904f4570 236 SUPERFAMILY SSF140931 50 215 6.41E-36 T 13-10-2018 IPR036597 Fido-like domain superfamily CLOST_1299 13fe465c97e4931f43119d0f6a028958 144 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 7 136 5.5E-31 T 13-10-2018 CLOST_1299 13fe465c97e4931f43119d0f6a028958 144 PIRSF PIRSF004923 1 143 1.6E-31 T 13-10-2018 IPR026268 Protein RseC CLOST_2030 898fbf025d449fe52282ab5c134bdb3a 173 PIRSF PIRSF000239 1 173 5.2E-57 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CLOST_2030 898fbf025d449fe52282ab5c134bdb3a 173 Pfam PF00578 AhpC/TSA family 5 134 3.9E-40 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CLOST_2030 898fbf025d449fe52282ab5c134bdb3a 173 Gene3D G3DSA:3.40.30.10 2 173 9.8E-69 T 13-10-2018 CLOST_2030 898fbf025d449fe52282ab5c134bdb3a 173 SUPERFAMILY SSF52833 4 171 5.18E-59 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_2109 426e3c054cd1610eeeace2ef8b01b687 602 SUPERFAMILY SSF53649 255 525 7.63E-18 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CLOST_2109 426e3c054cd1610eeeace2ef8b01b687 602 Gene3D G3DSA:3.40.720.10 252 549 1.1E-38 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CLOST_2109 426e3c054cd1610eeeace2ef8b01b687 602 Pfam PF00884 Sulfatase 255 525 1.5E-28 T 13-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 SUPERFAMILY SSF51735 201 446 4.62E-73 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 Gene3D G3DSA:1.10.285.10 381 447 1.3E-12 T 13-10-2018 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 SUPERFAMILY SSF53223 4 195 1.02E-74 T 13-10-2018 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 55 183 7.1E-50 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 Gene3D G3DSA:3.40.50.10860 53 188 2.1E-172 T 13-10-2018 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 Gene3D G3DSA:3.40.50.720 208 373 2.1E-172 T 13-10-2018 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 201 446 4.1E-81 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 Gene3D G3DSA:1.10.285.10 4 380 2.1E-172 T 13-10-2018 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 192 214 1.6E-29 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 234 254 1.6E-29 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 112 126 1.6E-29 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 1.6E-29 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 120 133 - T 13-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 PIRSF PIRSF000185 20 448 5.3E-125 T 13-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CLOST_2293 40dc1ece96f4c0d8547d9692431b8a6e 448 SMART SM00839 203 446 2.5E-78 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CLOST_2552 5c03d7c50b10afa7c2f5e988152021f5 264 Pfam PF12706 Beta-lactamase superfamily domain 24 218 1.8E-19 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_2552 5c03d7c50b10afa7c2f5e988152021f5 264 SMART SM00849 13 193 2.3E-10 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_2552 5c03d7c50b10afa7c2f5e988152021f5 264 Gene3D G3DSA:3.60.15.10 9 252 1.8E-40 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_2552 5c03d7c50b10afa7c2f5e988152021f5 264 SUPERFAMILY SSF56281 1 228 1.0E-43 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1458 2233962cec84593a6a0589aa7bc3a6d1 224 SMART SM00100 14 135 8.1E-8 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_1458 2233962cec84593a6a0589aa7bc3a6d1 224 Gene3D G3DSA:2.60.120.1460 2 221 3.3E-62 T 13-10-2018 CLOST_1458 2233962cec84593a6a0589aa7bc3a6d1 224 Pfam PF00027 Cyclic nucleotide-binding domain 36 123 2.2E-15 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain CLOST_1458 2233962cec84593a6a0589aa7bc3a6d1 224 Pfam PF13545 Crp-like helix-turn-helix domain 168 218 1.5E-7 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CLOST_1458 2233962cec84593a6a0589aa7bc3a6d1 224 SUPERFAMILY SSF46785 153 216 1.85E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1458 2233962cec84593a6a0589aa7bc3a6d1 224 SUPERFAMILY SSF51206 5 146 4.98E-31 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like CLOST_2408 019b3ca5067aa924e295a440980d9799 87 SUPERFAMILY SSF52833 1 77 2.39E-9 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_2408 019b3ca5067aa924e295a440980d9799 87 Pfam PF00462 Glutaredoxin 4 72 2.1E-8 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CLOST_2408 019b3ca5067aa924e295a440980d9799 87 Gene3D G3DSA:3.40.30.10 1 87 3.3E-13 T 13-10-2018 CLOST_0288 4013a1254a52078cf389fa84516d3383 381 Gene3D G3DSA:3.30.70.1380 240 329 1.5E-18 T 13-10-2018 CLOST_0288 4013a1254a52078cf389fa84516d3383 381 Hamap MF_01074 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein [larC]. 1 381 34.131 T 13-10-2018 IPR002822 Nickel insertion protein CLOST_0288 4013a1254a52078cf389fa84516d3383 381 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 4 377 9.8E-106 T 13-10-2018 IPR002822 Nickel insertion protein CLOST_0288 4013a1254a52078cf389fa84516d3383 381 Pfam PF01969 Protein of unknown function DUF111 3 377 3.6E-131 T 13-10-2018 IPR002822 Nickel insertion protein CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 SMART SM00382 330 462 2.3E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 Gene3D G3DSA:3.40.50.300 471 689 1.9E-113 T 13-10-2018 CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 SUPERFAMILY SSF52540 186 471 6.98E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 Gene3D G3DSA:2.30.30.940 556 627 1.9E-113 T 13-10-2018 CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 Pfam PF13538 UvrD-like helicase C-terminal domain 626 673 4.9E-13 T 13-10-2018 IPR027785 UvrD-like helicase C-terminal domain CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 SUPERFAMILY SSF52540 422 695 5.22E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 Pfam PF13604 AAA domain 317 504 2.7E-38 T 13-10-2018 CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 Gene3D G3DSA:3.40.50.300 307 695 1.9E-113 T 13-10-2018 CLOST_1268 76985e5ee2d8e3eb97fb372cd4815970 699 Pfam PF14490 Helix-hairpin-helix containing domain 146 228 1.1E-8 T 13-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CLOST_1101 47b1650b7173a94494a23f6a0d5c3575 186 SUPERFAMILY SSF52540 4 185 4.64E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1101 47b1650b7173a94494a23f6a0d5c3575 186 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 5 184 1.0E-57 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 CLOST_1101 47b1650b7173a94494a23f6a0d5c3575 186 PIRSF PIRSF006135 3 186 2.9E-57 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 CLOST_1101 47b1650b7173a94494a23f6a0d5c3575 186 Gene3D G3DSA:3.40.50.300 4 185 7.0E-60 T 13-10-2018 CLOST_1838 d73b528ee2d7ad23e5a672471b96c0c1 149 SUPERFAMILY SSF47162 74 146 5.49E-5 T 13-10-2018 CLOST_1838 d73b528ee2d7ad23e5a672471b96c0c1 149 Gene3D G3DSA:1.20.120.20 46 147 6.2E-6 T 13-10-2018 CLOST_2016 4d72219d2914b150316397d8ce934b91 84 Pfam PF11823 Protein of unknown function (DUF3343) 8 60 1.8E-12 T 13-10-2018 IPR021778 Domain of unknown function DUF3343 CLOST_1167 d3bbae379d1774ea44d1a525afbbeca5 255 PIRSF PIRSF005647 3 255 5.8E-65 T 13-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type CLOST_1167 d3bbae379d1774ea44d1a525afbbeca5 255 SUPERFAMILY SSF52540 1 253 2.78E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1167 d3bbae379d1774ea44d1a525afbbeca5 255 Gene3D G3DSA:3.40.50.300 4 254 6.9E-50 T 13-10-2018 CLOST_1167 d3bbae379d1774ea44d1a525afbbeca5 255 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 233 3.4E-16 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CLOST_1561 514a867f294a68061231f226bb6c2a61 126 SUPERFAMILY SSF47413 3 76 7.17E-13 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_1561 514a867f294a68061231f226bb6c2a61 126 Gene3D G3DSA:1.10.260.40 1 75 1.2E-21 T 13-10-2018 CLOST_1561 514a867f294a68061231f226bb6c2a61 126 SMART SM00530 8 69 2.1E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1561 514a867f294a68061231f226bb6c2a61 126 Pfam PF12844 Helix-turn-helix domain 6 71 1.0E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_2570 cf22383329a59f606a1edd6867cc8334 149 Gene3D G3DSA:2.40.50.140 1 113 1.4E-41 T 13-10-2018 CLOST_2570 cf22383329a59f606a1edd6867cc8334 149 SUPERFAMILY SSF50249 1 149 1.1E-44 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold CLOST_2570 cf22383329a59f606a1edd6867cc8334 149 Hamap MF_00984 Single-stranded DNA-binding protein. 1 107 32.026 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CLOST_2570 cf22383329a59f606a1edd6867cc8334 149 PIRSF PIRSF002070 1 147 9.7E-37 T 13-10-2018 CLOST_2570 cf22383329a59f606a1edd6867cc8334 149 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 149 1.4E-38 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CLOST_2570 cf22383329a59f606a1edd6867cc8334 149 Pfam PF00436 Single-strand binding protein family 1 103 1.9E-33 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 Gene3D G3DSA:1.10.10.10 11 147 6.6E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 ProSitePatterns PS01117 MarR-type HTH domain signature. 69 102 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 2.7E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.7E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.7E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.7E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 Pfam PF01047 MarR family 39 93 1.6E-14 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 SUPERFAMILY SSF46785 8 146 3.3E-31 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1320 cca40566d37dc7127ee6cba577a558d8 158 SMART SM00347 29 129 3.7E-20 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0785 52142dbdfd49cee6c7555cd85eef8450 134 Pfam PF14387 Domain of unknown function (DUF4418) 10 124 9.3E-24 T 13-10-2018 IPR025531 Protein of unknown function DUF4418 CLOST_1722 d4c0b5674073042e2c1caaa66435ad11 89 PIRSF PIRSF004669 1 89 1.6E-34 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CLOST_1722 d4c0b5674073042e2c1caaa66435ad11 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 5.0E-24 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CLOST_1722 d4c0b5674073042e2c1caaa66435ad11 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 5.0E-24 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CLOST_1722 d4c0b5674073042e2c1caaa66435ad11 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 5.0E-24 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CLOST_1722 d4c0b5674073042e2c1caaa66435ad11 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 88 7.3E-34 T 13-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CLOST_1722 d4c0b5674073042e2c1caaa66435ad11 89 Pfam PF01313 Bacterial export proteins, family 3 6 78 9.2E-30 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CLOST_0830 7ecc91804f666950180f4f536b4ca69e 179 SUPERFAMILY SSF54862 2 173 9.52E-37 T 13-10-2018 CLOST_0830 7ecc91804f666950180f4f536b4ca69e 179 Gene3D G3DSA:3.30.70.20 65 133 6.0E-27 T 13-10-2018 CLOST_0830 7ecc91804f666950180f4f536b4ca69e 179 Gene3D G3DSA:3.30.70.20 6 176 6.0E-27 T 13-10-2018 CLOST_0830 7ecc91804f666950180f4f536b4ca69e 179 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0830 7ecc91804f666950180f4f536b4ca69e 179 Pfam PF12800 4Fe-4S binding domain 9 22 0.0064 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0830 7ecc91804f666950180f4f536b4ca69e 179 Pfam PF13247 4Fe-4S dicluster domain 53 157 1.2E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0784 cf4d3c6f1ae94d7706d2af1a1e8eb2a2 223 Pfam PF09335 SNARE associated Golgi protein 60 181 2.1E-27 T 13-10-2018 IPR032816 SNARE associated Golgi protein CLOST_1275 8e3ec8cbac18959023718ca7c24311a8 342 Gene3D G3DSA:3.30.70.20 3 62 1.2E-5 T 13-10-2018 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 Pfam PF00375 Sodium:dicarboxylate symporter family 13 395 4.0E-68 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 Gene3D G3DSA:1.10.3860.10 3 401 2.0E-73 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 SUPERFAMILY SSF118215 13 396 7.45E-95 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 5.4E-16 T 13-10-2018 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 PRINTS PR00173 Glutamate-aspartate symporter signature 349 369 5.4E-16 T 13-10-2018 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 PRINTS PR00173 Glutamate-aspartate symporter signature 322 341 5.4E-16 T 13-10-2018 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 5.4E-16 T 13-10-2018 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 PRINTS PR00173 Glutamate-aspartate symporter signature 220 239 5.4E-16 T 13-10-2018 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 PRINTS PR00173 Glutamate-aspartate symporter signature 287 313 5.4E-16 T 13-10-2018 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 PRINTS PR00173 Glutamate-aspartate symporter signature 185 204 5.4E-16 T 13-10-2018 CLOST_0035 ce9d6c131084c5718b1ee67b8b9f8f9e 416 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 1 404 36.193 T 13-10-2018 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 CLOST_0283 e9969ff999f86d17287d4585fc41d081 293 Gene3D G3DSA:1.10.1670.50 234 293 2.9E-22 T 13-10-2018 CLOST_0283 e9969ff999f86d17287d4585fc41d081 293 Gene3D G3DSA:3.30.310.260 1 111 1.3E-42 T 13-10-2018 CLOST_0283 e9969ff999f86d17287d4585fc41d081 293 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 118 264 3.1E-6 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CLOST_0283 e9969ff999f86d17287d4585fc41d081 293 Gene3D G3DSA:1.10.340.30 112 233 3.1E-31 T 13-10-2018 CLOST_0283 e9969ff999f86d17287d4585fc41d081 293 SUPERFAMILY SSF48150 112 286 5.65E-33 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CLOST_0283 e9969ff999f86d17287d4585fc41d081 293 SMART SM00478 122 286 2.6E-11 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CLOST_0283 e9969ff999f86d17287d4585fc41d081 293 SUPERFAMILY SSF55945 9 111 6.28E-21 T 13-10-2018 CLOST_0283 e9969ff999f86d17287d4585fc41d081 293 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 16 116 5.1E-20 T 13-10-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 CLOST_1562 6b7ea05e77277ed3fbc1aa2d20f7dc7b 171 Pfam PF06114 IrrE N-terminal-like domain 14 138 7.3E-7 T 13-10-2018 IPR010359 IrrE N-terminal-like domain CLOST_2080 86fd423f3067258aa7c6937f005e40cd 169 Gene3D G3DSA:1.20.1260.10 1 167 1.3E-49 T 13-10-2018 IPR012347 Ferritin-like CLOST_2080 86fd423f3067258aa7c6937f005e40cd 169 SUPERFAMILY SSF47240 1 159 1.8E-55 T 13-10-2018 IPR009078 Ferritin-like superfamily CLOST_2080 86fd423f3067258aa7c6937f005e40cd 169 Pfam PF00210 Ferritin-like domain 8 143 7.9E-38 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CLOST_0802 e35f6dc255a6acca63591231c6bf781c 370 Pfam PF06826 Predicted Permease Membrane Region 201 366 3.3E-32 T 13-10-2018 IPR006512 YidE/YbjL duplication CLOST_0802 e35f6dc255a6acca63591231c6bf781c 370 Pfam PF06826 Predicted Permease Membrane Region 11 170 2.2E-24 T 13-10-2018 IPR006512 YidE/YbjL duplication CLOST_0972 cc5c9e137ae2bc11153aa4ddd43b287f 423 Gene3D G3DSA:3.40.50.300 212 419 4.7E-46 T 13-10-2018 CLOST_0972 cc5c9e137ae2bc11153aa4ddd43b287f 423 SMART SM00490 254 335 1.7E-28 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0972 cc5c9e137ae2bc11153aa4ddd43b287f 423 Pfam PF00270 DEAD/DEAH box helicase 26 191 5.6E-48 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CLOST_0972 cc5c9e137ae2bc11153aa4ddd43b287f 423 Gene3D G3DSA:3.40.50.300 1 206 2.1E-70 T 13-10-2018 CLOST_0972 cc5c9e137ae2bc11153aa4ddd43b287f 423 SMART SM00487 21 218 9.4E-57 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CLOST_0972 cc5c9e137ae2bc11153aa4ddd43b287f 423 Pfam PF00271 Helicase conserved C-terminal domain 241 335 4.2E-25 T 13-10-2018 IPR001650 Helicase, C-terminal CLOST_0972 cc5c9e137ae2bc11153aa4ddd43b287f 423 SUPERFAMILY SSF52540 71 356 3.18E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1886 1185f12bb3435f9b8d41919b8aecc6f9 445 Gene3D G3DSA:2.30.42.10 4 80 2.4E-5 T 13-10-2018 CLOST_1886 1185f12bb3435f9b8d41919b8aecc6f9 445 Pfam PF04459 Protein of unknown function (DUF512) 226 427 7.4E-75 T 13-10-2018 IPR007549 Domain of unknown function DUF512 CLOST_1886 1185f12bb3435f9b8d41919b8aecc6f9 445 Gene3D G3DSA:3.20.20.70 121 360 1.9E-9 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1886 1185f12bb3435f9b8d41919b8aecc6f9 445 SUPERFAMILY SSF50156 12 71 1.04E-7 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 CLOST_1886 1185f12bb3435f9b8d41919b8aecc6f9 445 SUPERFAMILY SSF102114 93 245 5.1E-12 T 13-10-2018 CLOST_0696 c0aab8d80a29a03ac0ca2ad2b3e15fc4 313 SUPERFAMILY SSF55729 125 285 2.01E-11 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0659 172199c38b0901d3780cac5096d554e4 691 Gene3D G3DSA:3.30.450.20 39 241 2.3E-6 T 13-10-2018 CLOST_0659 172199c38b0901d3780cac5096d554e4 691 SUPERFAMILY SSF55073 534 688 2.04E-32 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_0659 172199c38b0901d3780cac5096d554e4 691 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 531 685 1.7E-27 T 13-10-2018 IPR000160 GGDEF domain CLOST_0659 172199c38b0901d3780cac5096d554e4 691 SMART SM00267 520 691 2.5E-28 T 13-10-2018 IPR000160 GGDEF domain CLOST_0659 172199c38b0901d3780cac5096d554e4 691 Gene3D G3DSA:3.30.70.270 516 690 3.9E-35 T 13-10-2018 CLOST_0659 172199c38b0901d3780cac5096d554e4 691 Pfam PF00990 Diguanylate cyclase, GGDEF domain 531 684 2.4E-29 T 13-10-2018 IPR000160 GGDEF domain CLOST_1139 bf9b93736977daded483b8643cbea57f 450 Pfam PF02386 Cation transport protein 15 432 8.3E-64 T 13-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CLOST_1139 bf9b93736977daded483b8643cbea57f 450 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 33 421 4.3E-113 T 13-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 CLOST_2330 58c45f82edc357a55fc70abe6c3496db 169 Pfam PF05130 FlgN protein 11 150 2.4E-8 T 13-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CLOST_2291 f4604f4a6cbac5a4dc1cfa8e0cd894bd 246 Pfam PF00881 Nitroreductase family 10 163 2.1E-26 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CLOST_2291 f4604f4a6cbac5a4dc1cfa8e0cd894bd 246 SUPERFAMILY SSF55469 1 243 9.03E-69 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_2291 f4604f4a6cbac5a4dc1cfa8e0cd894bd 246 PIRSF PIRSF005426 1 245 1.7E-88 T 13-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 CLOST_2291 f4604f4a6cbac5a4dc1cfa8e0cd894bd 246 Gene3D G3DSA:3.40.109.10 1 246 1.6E-76 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_0744 1a469a60b314d63fe00f423158779f15 474 Pfam PF13520 Amino acid permease 5 419 1.3E-42 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CLOST_0744 1a469a60b314d63fe00f423158779f15 474 PIRSF PIRSF006060 1 471 1.4E-52 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CLOST_0744 1a469a60b314d63fe00f423158779f15 474 Gene3D G3DSA:1.20.1740.10 1 463 6.5E-65 T 13-10-2018 CLOST_0499 8db4943e0366de27283d3de866fe2f02 187 Gene3D G3DSA:1.10.3210.10 2 186 4.2E-41 T 13-10-2018 CLOST_0499 8db4943e0366de27283d3de866fe2f02 187 SMART SM00471 29 144 0.0043 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0499 8db4943e0366de27283d3de866fe2f02 187 SUPERFAMILY SSF109604 5 161 7.68E-35 T 13-10-2018 CLOST_0499 8db4943e0366de27283d3de866fe2f02 187 Pfam PF13023 HD domain 13 171 6.8E-37 T 13-10-2018 IPR006674 HD domain CLOST_1844 77029398a0fed5ebdcde2cd7f0328d51 118 Pfam PF03780 Asp23 family, cell envelope-related function 9 115 2.7E-31 T 13-10-2018 IPR005531 Alkaline shock protein Asp23 CLOST_1400 df513b38b85fd6daf09007056c030182 185 PIRSF PIRSF006091 1 185 5.8E-38 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CLOST_1400 df513b38b85fd6daf09007056c030182 185 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 182 3.3E-30 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CLOST_1400 df513b38b85fd6daf09007056c030182 185 Pfam PF04205 FMN-binding domain 90 178 1.2E-15 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOST_1400 df513b38b85fd6daf09007056c030182 185 SMART SM00900 90 180 2.2E-18 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CLOST_1400 df513b38b85fd6daf09007056c030182 185 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 2 182 21.866 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 CLOST_1991 2122ac0c9356993b0dc123cc7ca39871 201 SUPERFAMILY SSF51366 5 198 1.88E-53 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CLOST_1991 2122ac0c9356993b0dc123cc7ca39871 201 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 4 201 32.854 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CLOST_1991 2122ac0c9356993b0dc123cc7ca39871 201 Gene3D G3DSA:3.20.20.70 2 201 9.4E-65 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1991 2122ac0c9356993b0dc123cc7ca39871 201 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 196 9.1E-50 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CLOST_1001 73dac86725f3fe8191fd3439519c35a2 431 Pfam PF00202 Aminotransferase class-III 32 414 2.0E-74 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CLOST_1001 73dac86725f3fe8191fd3439519c35a2 431 Gene3D G3DSA:3.40.640.10 71 319 1.6E-161 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1001 73dac86725f3fe8191fd3439519c35a2 431 SUPERFAMILY SSF53383 1 426 7.49E-124 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_1001 73dac86725f3fe8191fd3439519c35a2 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 93.107 T 13-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CLOST_1001 73dac86725f3fe8191fd3439519c35a2 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CLOST_1001 73dac86725f3fe8191fd3439519c35a2 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 425 4.3E-180 T 13-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CLOST_1001 73dac86725f3fe8191fd3439519c35a2 431 Gene3D G3DSA:3.90.1150.10 9 418 1.6E-161 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 SUPERFAMILY SSF52440 1 113 6.91E-49 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 444 3.7E-215 T 13-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 3.5E-79 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 SMART SM00878 336 442 3.6E-61 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.4E-45 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 SUPERFAMILY SSF56059 83 352 3.87E-70 T 13-10-2018 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.3E-39 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 SUPERFAMILY SSF51246 332 444 6.28E-43 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 Gene3D G3DSA:3.30.470.130 1 447 9.2E-194 T 13-10-2018 CLOST_0890 a68b16c652ef10796ef44f342429f2d9 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CLOST_0315 9fe46c55c10835d83f66937ecf96876d 80 Pfam PF02517 CAAX protease self-immunity 10 69 2.0E-7 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CLOST_1879 f6a0849da129dabc85c05752cbd8f4a3 90 Pfam PF02325 YGGT family 9 83 9.8E-21 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 CLOST_2496 5c2a20948a8af05d71481c3268ee411c 771 Pfam PF02687 FtsX-like permease family 282 373 3.7E-8 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 SUPERFAMILY SSF143800 1 64 4.32E-26 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 64 7.9E-31 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 Pfam PF01197 Ribosomal protein L31 1 64 2.4E-31 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 Gene3D G3DSA:2.30.170.50 1 65 2.6E-31 T 13-10-2018 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 PRINTS PR01249 Ribosomal protein L31 signature 30 45 2.2E-21 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 PRINTS PR01249 Ribosomal protein L31 signature 45 63 2.2E-21 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.2E-21 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_2136 a21598fc829b36a6c6874efac6b27eff 65 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 65 26.234 T 13-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_0750 53d46842e98e2ffd4726ba74d68e6586 111 SUPERFAMILY SSF52833 4 104 4.93E-17 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_0750 53d46842e98e2ffd4726ba74d68e6586 111 Pfam PF00085 Thioredoxin 18 87 2.7E-8 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 CLOST_0750 53d46842e98e2ffd4726ba74d68e6586 111 Gene3D G3DSA:3.40.30.10 8 106 1.3E-17 T 13-10-2018 CLOST_1128 56d1b5233d4e962a6465a64ef32ec305 253 SUPERFAMILY SSF55729 145 242 1.21E-10 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1128 56d1b5233d4e962a6465a64ef32ec305 253 Gene3D G3DSA:3.40.630.30 106 250 3.0E-9 T 13-10-2018 CLOST_1128 56d1b5233d4e962a6465a64ef32ec305 253 Pfam PF00583 Acetyltransferase (GNAT) family 142 237 2.8E-7 T 13-10-2018 IPR000182 GNAT domain CLOST_0774 2e74c521f5a1dd488892bae0138e0d91 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 137 2.4E-33 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CLOST_0774 2e74c521f5a1dd488892bae0138e0d91 346 Pfam PF00107 Zinc-binding dehydrogenase 178 302 2.1E-32 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CLOST_0774 2e74c521f5a1dd488892bae0138e0d91 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CLOST_0774 2e74c521f5a1dd488892bae0138e0d91 346 SUPERFAMILY SSF50129 3 174 3.96E-59 T 13-10-2018 IPR011032 GroES-like superfamily CLOST_0774 2e74c521f5a1dd488892bae0138e0d91 346 Gene3D G3DSA:3.90.180.10 11 330 1.1E-119 T 13-10-2018 CLOST_0774 2e74c521f5a1dd488892bae0138e0d91 346 Gene3D G3DSA:3.40.50.720 154 291 1.1E-119 T 13-10-2018 CLOST_0774 2e74c521f5a1dd488892bae0138e0d91 346 SMART SM00829 10 343 5.8E-6 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CLOST_0774 2e74c521f5a1dd488892bae0138e0d91 346 SUPERFAMILY SSF51735 141 310 2.34E-45 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1861 fff0af05cb07420bba53983b8a0c9295 85 Pfam PF04025 Domain of unknown function (DUF370) 3 74 1.2E-35 T 13-10-2018 IPR007169 Extracellular matrix regulatory protein A CLOST_1861 fff0af05cb07420bba53983b8a0c9295 85 Hamap MF_01503 UPF0296 protein . 1 85 27.791 T 13-10-2018 IPR007169 Extracellular matrix regulatory protein A CLOST_1861 fff0af05cb07420bba53983b8a0c9295 85 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 3 76 6.0E-24 T 13-10-2018 IPR007169 Extracellular matrix regulatory protein A CLOST_1460 d236a36832f1fc0f8649f27bd1f48b63 349 Pfam PF01522 Polysaccharide deacetylase 116 245 2.7E-11 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CLOST_1460 d236a36832f1fc0f8649f27bd1f48b63 349 SUPERFAMILY SSF88713 80 245 2.78E-20 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CLOST_1460 d236a36832f1fc0f8649f27bd1f48b63 349 Gene3D G3DSA:3.20.20.370 64 293 5.0E-35 T 13-10-2018 CLOST_2432 084d318220abcfc68fa932f0ff1a10b9 311 SUPERFAMILY SSF142535 13 297 4.19E-36 T 13-10-2018 CLOST_2432 084d318220abcfc68fa932f0ff1a10b9 311 Pfam PF04414 D-aminoacyl-tRNA deacylase 80 296 7.1E-39 T 13-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 CLOST_2432 084d318220abcfc68fa932f0ff1a10b9 311 Gene3D G3DSA:3.40.630.50 9 204 1.0E-8 T 13-10-2018 CLOST_1414 2945de617d188f748df518c1b5a7e8f5 292 Gene3D G3DSA:3.60.15.10 2 229 2.1E-29 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1414 2945de617d188f748df518c1b5a7e8f5 292 Pfam PF00753 Metallo-beta-lactamase superfamily 26 203 4.0E-16 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1414 2945de617d188f748df518c1b5a7e8f5 292 SUPERFAMILY SSF56281 5 280 1.25E-33 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CLOST_1414 2945de617d188f748df518c1b5a7e8f5 292 SMART SM00849 17 203 6.4E-16 T 13-10-2018 IPR001279 Metallo-beta-lactamase CLOST_1156 850d4ec81ebce34e88cb3d243e657c55 79 Gene3D G3DSA:3.30.70.20 52 78 4.7E-5 T 13-10-2018 CLOST_1156 850d4ec81ebce34e88cb3d243e657c55 79 Gene3D G3DSA:3.30.70.20 3 51 2.8E-5 T 13-10-2018 CLOST_1156 850d4ec81ebce34e88cb3d243e657c55 79 SUPERFAMILY SSF54862 8 77 1.14E-16 T 13-10-2018 CLOST_1156 850d4ec81ebce34e88cb3d243e657c55 79 Pfam PF12838 4Fe-4S dicluster domain 23 71 1.5E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1156 850d4ec81ebce34e88cb3d243e657c55 79 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 60 71 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2001 9174ed08adcf36e53df0ee76e7d0e991 333 Pfam PF13303 Phosphotransferase system, EIIC 6 328 5.8E-112 T 13-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CLOST_0263 5a2c2b6790441d38d8a43d46822ca719 306 SMART SM01091 217 300 9.9E-16 T 13-10-2018 IPR005170 Transporter-associated domain CLOST_0263 5a2c2b6790441d38d8a43d46822ca719 306 Gene3D G3DSA:3.10.580.10 61 210 1.3E-54 T 13-10-2018 CLOST_0263 5a2c2b6790441d38d8a43d46822ca719 306 Gene3D G3DSA:3.30.465.10 211 302 2.8E-18 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 CLOST_0263 5a2c2b6790441d38d8a43d46822ca719 306 SUPERFAMILY SSF54631 76 211 3.79E-34 T 13-10-2018 CLOST_0263 5a2c2b6790441d38d8a43d46822ca719 306 Pfam PF00571 CBS domain 149 200 8.5E-6 T 13-10-2018 IPR000644 CBS domain CLOST_0263 5a2c2b6790441d38d8a43d46822ca719 306 Pfam PF00571 CBS domain 81 133 6.6E-7 T 13-10-2018 IPR000644 CBS domain CLOST_0263 5a2c2b6790441d38d8a43d46822ca719 306 SUPERFAMILY SSF56176 215 299 1.64E-16 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 CLOST_0263 5a2c2b6790441d38d8a43d46822ca719 306 Pfam PF03471 Transporter associated domain 219 298 4.3E-15 T 13-10-2018 IPR005170 Transporter-associated domain CLOST_0008 8f958fbd03fe8da178abb629cd67a777 99 Pfam PF12732 YtxH-like protein 9 53 4.6E-12 T 13-10-2018 IPR024623 Uncharacterised protein family YtxH CLOST_0494 0a41e281814b934f53c013e080f9219c 287 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 225 279 2.4E-22 T 13-10-2018 IPR019264 Domain of unknown function DUF2179 CLOST_0494 0a41e281814b934f53c013e080f9219c 287 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 15 220 6.0E-59 T 13-10-2018 IPR003740 Uncharacterised membrane protein YitT CLOST_0494 0a41e281814b934f53c013e080f9219c 287 PIRSF PIRSF006483 1 287 3.6E-88 T 13-10-2018 IPR003740 Uncharacterised membrane protein YitT CLOST_0494 0a41e281814b934f53c013e080f9219c 287 Gene3D G3DSA:3.30.70.120 196 271 2.3E-24 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 549 7.2E-212 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 684 25.954 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 SUPERFAMILY SSF109604 337 489 2.57E-17 T 13-10-2018 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 685 4.8E-231 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 SMART SM00836 579 684 0.0042 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 Pfam PF05746 DALR anticodon binding domain 581 680 1.5E-7 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 392 411 4.8E-34 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 244 259 4.8E-34 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 316 332 4.8E-34 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 4.8E-34 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_1770 7676ac2191f46fdf691ecc7db953b574 687 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 4.8E-34 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CLOST_0396 a29e76ffc9f852c33c5b448627ddc68d 452 PIRSF PIRSF006060 3 451 1.7E-82 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CLOST_0396 a29e76ffc9f852c33c5b448627ddc68d 452 Pfam PF13520 Amino acid permease 25 423 1.3E-56 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CLOST_0396 a29e76ffc9f852c33c5b448627ddc68d 452 Gene3D G3DSA:1.20.1740.10 17 452 1.1E-89 T 13-10-2018 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 PRINTS PR01402 Mutator MutX protein signature 21 36 3.9E-22 T 13-10-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 PRINTS PR01402 Mutator MutX protein signature 97 117 3.9E-22 T 13-10-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 PRINTS PR01402 Mutator MutX protein signature 133 153 3.9E-22 T 13-10-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 PRINTS PR01402 Mutator MutX protein signature 67 93 3.9E-22 T 13-10-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 PRINTS PR01402 Mutator MutX protein signature 3 21 3.9E-22 T 13-10-2018 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 Pfam PF00293 NUDIX domain 7 126 6.7E-18 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 SUPERFAMILY SSF55811 3 141 3.38E-26 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 CLOST_1023 b069dfff5959ef579ec599b9a5f09f76 153 Gene3D G3DSA:3.90.79.10 3 152 7.0E-36 T 13-10-2018 CLOST_0705 0b529362e456bd615be1b71a821e85cd 117 Pfam PF07343 Protein of unknown function (DUF1475) 11 93 9.0E-7 T 13-10-2018 IPR009943 Protein of unknown function DUF1475 CLOST_1223 fbe48eb145abb85a2a4ef7769b569db2 447 Gene3D G3DSA:1.25.40.80 142 305 1.6E-41 T 13-10-2018 CLOST_1223 fbe48eb145abb85a2a4ef7769b569db2 447 Gene3D G3DSA:1.10.579.10 309 446 4.9E-61 T 13-10-2018 CLOST_1223 fbe48eb145abb85a2a4ef7769b569db2 447 SUPERFAMILY SSF48173 213 441 3.92E-51 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 CLOST_1223 fbe48eb145abb85a2a4ef7769b569db2 447 ProSitePatterns PS01084 DNA photolyases class 2 signature 2. 410 429 - T 13-10-2018 IPR032673 DNA photolyase class 2, conserved site CLOST_1223 fbe48eb145abb85a2a4ef7769b569db2 447 Gene3D G3DSA:3.40.50.620 1 141 2.8E-33 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CLOST_1223 fbe48eb145abb85a2a4ef7769b569db2 447 Pfam PF00875 DNA photolyase 21 173 5.9E-17 T 13-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 CLOST_1223 fbe48eb145abb85a2a4ef7769b569db2 447 SUPERFAMILY SSF52425 20 191 1.96E-28 T 13-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 CLOST_0528 faa07356b33b193894011d71888219e2 92 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 4 87 3.0E-33 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CLOST_0528 faa07356b33b193894011d71888219e2 92 SUPERFAMILY SSF101386 4 91 3.74E-27 T 13-10-2018 CLOST_0528 faa07356b33b193894011d71888219e2 92 Gene3D G3DSA:1.10.287.1080 1 92 1.2E-32 T 13-10-2018 CLOST_0528 faa07356b33b193894011d71888219e2 92 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 22.09 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CLOST_0528 faa07356b33b193894011d71888219e2 92 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 5 90 2.5E-19 T 13-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CLOST_1762 6bafe669bcaabb91b76b3620d65c47b8 368 SUPERFAMILY SSF56752 9 241 3.01E-45 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 CLOST_1762 6bafe669bcaabb91b76b3620d65c47b8 368 Gene3D G3DSA:3.20.10.10 103 253 8.2E-35 T 13-10-2018 CLOST_1762 6bafe669bcaabb91b76b3620d65c47b8 368 Gene3D G3DSA:3.30.470.10 5 97 9.8E-13 T 13-10-2018 CLOST_1762 6bafe669bcaabb91b76b3620d65c47b8 368 Pfam PF01063 Amino-transferase class IV 21 230 3.2E-36 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 SMART SM00851 12 126 1.4E-49 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 SUPERFAMILY SSF53927 204 504 5.11E-111 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 Gene3D G3DSA:3.40.140.20 201 354 3.7E-56 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 Gene3D G3DSA:3.40.140.20 369 504 1.5E-50 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 SMART SM00798 131 438 9.4E-153 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 Pfam PF02142 MGS-like domain 12 125 1.9E-22 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 SUPERFAMILY SSF52335 2 189 2.38E-63 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 504 39.288 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 PIRSF PIRSF000414 1 504 2.5E-193 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2 504 4.0E-176 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 Gene3D G3DSA:3.40.50.1380 1 192 8.4E-81 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily CLOST_0338 18f7a4ea36dcdaf37bbf589dad06389e 504 Pfam PF01808 AICARFT/IMPCHase bienzyme 131 436 8.7E-105 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CLOST_0701 ed4a20d272d08c053c021c37cb0316e4 448 SUPERFAMILY SSF102114 168 372 1.02E-22 T 13-10-2018 CLOST_0701 ed4a20d272d08c053c021c37cb0316e4 448 SMART SM00729 177 380 1.7E-12 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0701 ed4a20d272d08c053c021c37cb0316e4 448 Pfam PF04055 Radical SAM superfamily 184 340 2.1E-10 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0701 ed4a20d272d08c053c021c37cb0316e4 448 Gene3D G3DSA:3.20.20.70 150 378 3.8E-9 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0701 ed4a20d272d08c053c021c37cb0316e4 448 Pfam PF02310 B12 binding domain 24 116 7.9E-12 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CLOST_0564 6d83f805561cd89c9c2ef9f681f1bf1a 289 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 253 283 2.7E-4 T 13-10-2018 CLOST_0594 c91cc3344dc361b831a60e974c29452c 202 Pfam PF01926 50S ribosome-binding GTPase 25 143 6.1E-22 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 CLOST_0594 c91cc3344dc361b831a60e974c29452c 202 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 192 27.767 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CLOST_0594 c91cc3344dc361b831a60e974c29452c 202 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 188 2.3E-71 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CLOST_0594 c91cc3344dc361b831a60e974c29452c 202 Gene3D G3DSA:3.40.50.300 1 197 1.5E-54 T 13-10-2018 CLOST_0594 c91cc3344dc361b831a60e974c29452c 202 SUPERFAMILY SSF52540 15 194 2.01E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1996 59f05d2d7d3b0dfefce5741869dfe448 234 Pfam PF12837 4Fe-4S binding domain 5 28 6.0E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1996 59f05d2d7d3b0dfefce5741869dfe448 234 Gene3D G3DSA:3.30.70.20 1 35 1.1E-7 T 13-10-2018 CLOST_1996 59f05d2d7d3b0dfefce5741869dfe448 234 SUPERFAMILY SSF54862 4 66 7.94E-19 T 13-10-2018 CLOST_1996 59f05d2d7d3b0dfefce5741869dfe448 234 Gene3D G3DSA:3.30.70.20 36 99 1.5E-5 T 13-10-2018 CLOST_0602 f3fdfa937ccf4a0ce4cd3481b0f4eca3 173 Gene3D G3DSA:1.10.1760.20 1 168 8.9E-12 T 13-10-2018 CLOST_0602 f3fdfa937ccf4a0ce4cd3481b0f4eca3 173 PIRSF PIRSF027391 1 172 3.6E-51 T 13-10-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I CLOST_0602 f3fdfa937ccf4a0ce4cd3481b0f4eca3 173 Pfam PF07456 Heptaprenyl diphosphate synthase component I 13 159 4.7E-42 T 13-10-2018 IPR010898 Heptaprenyl diphosphate synthase component I CLOST_2221 ea76936594345b83b8aa974d0ffd48c0 179 Pfam PF05991 YacP-like NYN domain 9 173 3.5E-47 T 13-10-2018 IPR010298 Protein of unknown function DUF901 CLOST_2421 81ed4b57f754645c844ad648b6d07ec4 280 SUPERFAMILY SSF103481 42 132 2.48E-8 T 13-10-2018 CLOST_2421 81ed4b57f754645c844ad648b6d07ec4 280 Pfam PF00892 EamA-like transporter family 141 266 7.5E-12 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_2421 81ed4b57f754645c844ad648b6d07ec4 280 Pfam PF00892 EamA-like transporter family 8 131 1.3E-13 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CLOST_2421 81ed4b57f754645c844ad648b6d07ec4 280 SUPERFAMILY SSF103481 193 267 2.62E-7 T 13-10-2018 CLOST_1207 d9d7c70e742864f7945c9695e6cfc328 53 SUPERFAMILY SSF89360 4 50 5.1E-7 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 CLOST_0090 798c33106c9606bf9a2bd39c792589df 218 SUPERFAMILY SSF161098 10 204 3.79E-45 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0090 798c33106c9606bf9a2bd39c792589df 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 215 1.6E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0090 798c33106c9606bf9a2bd39c792589df 218 Gene3D G3DSA:1.10.3720.10 7 218 4.2E-47 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1916 84128ff9f9a08d0ef1a13bb25763872c 196 Pfam PF03358 NADPH-dependent FMN reductase 1 131 1.3E-22 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CLOST_1916 84128ff9f9a08d0ef1a13bb25763872c 196 Gene3D G3DSA:3.40.50.360 1 188 2.1E-36 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_1916 84128ff9f9a08d0ef1a13bb25763872c 196 SUPERFAMILY SSF52218 1 193 6.77E-31 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0992 a2eb5be05fd87a03bb9d8dfeffed3b52 254 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 1.8E-42 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 CLOST_0992 a2eb5be05fd87a03bb9d8dfeffed3b52 254 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 248 9.8E-103 T 13-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CLOST_0992 a2eb5be05fd87a03bb9d8dfeffed3b52 254 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 CLOST_0992 a2eb5be05fd87a03bb9d8dfeffed3b52 254 Gene3D G3DSA:3.30.950.10 111 230 1.9E-49 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 CLOST_0992 a2eb5be05fd87a03bb9d8dfeffed3b52 254 SUPERFAMILY SSF53790 2 248 1.07E-65 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 CLOST_0992 a2eb5be05fd87a03bb9d8dfeffed3b52 254 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 CLOST_0992 a2eb5be05fd87a03bb9d8dfeffed3b52 254 Gene3D G3DSA:3.40.1010.10 1 110 1.0E-31 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 CLOST_2537 52e39183b5afb8721ba675ccb92c8a8c 139 Pfam PF12724 Flavodoxin domain 4 92 4.4E-12 T 13-10-2018 IPR026816 Flavodoxin domain CLOST_2537 52e39183b5afb8721ba675ccb92c8a8c 139 SUPERFAMILY SSF52218 1 133 3.14E-16 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_2537 52e39183b5afb8721ba675ccb92c8a8c 139 Gene3D G3DSA:3.40.50.360 2 135 2.7E-13 T 13-10-2018 IPR029039 Flavoprotein-like superfamily CLOST_0295 55f213cd308f583eedce80eb69e01388 235 SUPERFAMILY SSF56037 51 229 3.66E-37 T 13-10-2018 CLOST_0295 55f213cd308f583eedce80eb69e01388 235 Gene3D G3DSA:3.50.40.10 74 209 2.1E-5 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 CLOST_0295 55f213cd308f583eedce80eb69e01388 235 Pfam PF03483 B3/4 domain 67 198 1.5E-23 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CLOST_0295 55f213cd308f583eedce80eb69e01388 235 SMART SM00873 64 217 6.4E-17 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CLOST_0971 8cc350830b9f8c06eb46378c6cd81622 627 SUPERFAMILY SSF51445 132 548 2.9E-87 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily CLOST_0971 8cc350830b9f8c06eb46378c6cd81622 627 Gene3D G3DSA:2.60.40.1180 545 625 2.0E-6 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta CLOST_0971 8cc350830b9f8c06eb46378c6cd81622 627 Gene3D G3DSA:3.20.20.80 132 535 3.0E-116 T 13-10-2018 CLOST_0971 8cc350830b9f8c06eb46378c6cd81622 627 SMART SM00642 144 541 1.9E-69 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CLOST_0971 8cc350830b9f8c06eb46378c6cd81622 627 SUPERFAMILY SSF51011 556 624 9.6E-7 T 13-10-2018 CLOST_0971 8cc350830b9f8c06eb46378c6cd81622 627 Pfam PF00128 Alpha amylase, catalytic domain 194 500 1.1E-62 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CLOST_2153 14fcc8d31f55fcd0ee08efa20debe915 245 Gene3D G3DSA:3.40.109.30 136 238 2.7E-6 T 13-10-2018 CLOST_2153 14fcc8d31f55fcd0ee08efa20debe915 245 Gene3D G3DSA:3.40.109.10 1 129 1.3E-19 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_2153 14fcc8d31f55fcd0ee08efa20debe915 245 Pfam PF14512 Putative TM nitroreductase 3 213 4.3E-35 T 13-10-2018 IPR029478 Putative nitroreductase TM1586 CLOST_2153 14fcc8d31f55fcd0ee08efa20debe915 245 SUPERFAMILY SSF55469 4 181 1.57E-12 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CLOST_2204 ce4af1984cccde57a7405115d8cc0659 391 SUPERFAMILY SSF53822 36 383 3.77E-85 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_2204 ce4af1984cccde57a7405115d8cc0659 391 Pfam PF13458 Periplasmic binding protein 37 380 3.2E-61 T 13-10-2018 IPR028081 Leucine-binding protein domain CLOST_2204 ce4af1984cccde57a7405115d8cc0659 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 38 54 1.1E-7 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOST_2204 ce4af1984cccde57a7405115d8cc0659 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 294 307 1.1E-7 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOST_2204 ce4af1984cccde57a7405115d8cc0659 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 79 97 1.1E-7 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOST_2204 ce4af1984cccde57a7405115d8cc0659 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 76 1.1E-7 T 13-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CLOST_2204 ce4af1984cccde57a7405115d8cc0659 391 Gene3D G3DSA:3.40.50.2300 161 290 1.2E-93 T 13-10-2018 CLOST_2204 ce4af1984cccde57a7405115d8cc0659 391 Gene3D G3DSA:3.40.50.2300 39 358 1.2E-93 T 13-10-2018 CLOST_1374 9aae300afa620bba27d85a79c61d9abe 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 1.4E-31 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1374 9aae300afa620bba27d85a79c61d9abe 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 24.502 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1374 9aae300afa620bba27d85a79c61d9abe 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 1.8E-38 T 13-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1374 9aae300afa620bba27d85a79c61d9abe 102 SUPERFAMILY SSF141091 1 101 5.36E-34 T 13-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1374 9aae300afa620bba27d85a79c61d9abe 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 13-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CLOST_0838 ff3910e9f2c629296de1570f684fe997 185 Pfam PF13237 4Fe-4S dicluster domain 89 154 1.4E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_0838 ff3910e9f2c629296de1570f684fe997 185 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_0838 ff3910e9f2c629296de1570f684fe997 185 Gene3D G3DSA:3.30.70.20 44 184 1.0E-24 T 13-10-2018 CLOST_0838 ff3910e9f2c629296de1570f684fe997 185 SUPERFAMILY SSF54862 1 162 4.02E-40 T 13-10-2018 CLOST_1424 e36cdda3a234f67e354e128e746f986c 310 Pfam PF16916 Dimerisation domain of Zinc Transporter 228 303 5.2E-15 T 13-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain CLOST_1424 e36cdda3a234f67e354e128e746f986c 310 Pfam PF01545 Cation efflux family 31 223 2.2E-45 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CLOST_1424 e36cdda3a234f67e354e128e746f986c 310 SUPERFAMILY SSF160240 226 305 1.7E-16 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 CLOST_1424 e36cdda3a234f67e354e128e746f986c 310 Gene3D G3DSA:3.30.70.1350 225 306 1.4E-19 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 CLOST_1424 e36cdda3a234f67e354e128e746f986c 310 SUPERFAMILY SSF161111 28 224 2.48E-49 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily CLOST_1424 e36cdda3a234f67e354e128e746f986c 310 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 31 304 1.1E-65 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CLOST_1424 e36cdda3a234f67e354e128e746f986c 310 Gene3D G3DSA:1.20.1510.10 29 223 1.8E-54 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily CLOST_2292 398b6670f53406eaaaf9d83496ae2ebc 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_2292 398b6670f53406eaaaf9d83496ae2ebc 56 Gene3D G3DSA:3.30.70.20 2 54 1.8E-23 T 13-10-2018 CLOST_2292 398b6670f53406eaaaf9d83496ae2ebc 56 SUPERFAMILY SSF54862 1 55 7.41E-19 T 13-10-2018 CLOST_2292 398b6670f53406eaaaf9d83496ae2ebc 56 Pfam PF12838 4Fe-4S dicluster domain 8 52 2.8E-10 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_2292 398b6670f53406eaaaf9d83496ae2ebc 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1889 93436f9c8625e3e141447d3bb386a0b1 154 Pfam PF03477 ATP cone domain 50 136 4.1E-20 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CLOST_1889 93436f9c8625e3e141447d3bb386a0b1 154 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 5.6E-64 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CLOST_1889 93436f9c8625e3e141447d3bb386a0b1 154 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 82.831 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CLOST_1843 90a77542925579d321558519bd2ad6c7 547 Gene3D G3DSA:1.25.40.340 4 188 5.5E-9 T 13-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CLOST_1843 90a77542925579d321558519bd2ad6c7 547 SMART SM01120 34 199 9.2E-59 T 13-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CLOST_1843 90a77542925579d321558519bd2ad6c7 547 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 9 547 6.8E-200 T 13-10-2018 IPR019986 DAK2 domain-containing protein YloV CLOST_1843 90a77542925579d321558519bd2ad6c7 547 Pfam PF02734 DAK2 domain 34 198 1.3E-41 T 13-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CLOST_1843 90a77542925579d321558519bd2ad6c7 547 Pfam PF13684 Dihydroxyacetone kinase family 232 547 2.3E-121 T 13-10-2018 IPR033470 Uncharacterised protein, DhaK domain CLOST_1843 90a77542925579d321558519bd2ad6c7 547 SMART SM01121 232 547 4.9E-163 T 13-10-2018 IPR033470 Uncharacterised protein, DhaK domain CLOST_1843 90a77542925579d321558519bd2ad6c7 547 SUPERFAMILY SSF101473 4 199 3.92E-41 T 13-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CLOST_1091 e667a084a2997afecb35ace817079d6f 182 Gene3D G3DSA:1.10.8.1150 116 182 2.0E-10 T 13-10-2018 CLOST_1091 e667a084a2997afecb35ace817079d6f 182 Pfam PF02618 YceG-like family 120 181 1.3E-6 T 13-10-2018 IPR003770 Endolytic murein transglycosylase CLOST_1168 a105f3f0c9260d33370a02cb0d7ccb44 314 SUPERFAMILY SSF51717 69 232 3.77E-5 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1168 a105f3f0c9260d33370a02cb0d7ccb44 314 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 16 258 2.7E-42 T 13-10-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel CLOST_1168 a105f3f0c9260d33370a02cb0d7ccb44 314 Gene3D G3DSA:3.20.20.20 15 314 1.2E-112 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1003 7be6d79be0d369a7fcc725269969e516 431 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 384 2.9E-11 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_0408 eddb1fbb965b950067253cf7bb9241fa 65 PIRSF PIRSF039008 1 65 1.8E-25 T 13-10-2018 IPR026042 Stress response protein YjbJ CLOST_0408 eddb1fbb965b950067253cf7bb9241fa 65 SUPERFAMILY SSF69047 1 64 3.53E-21 T 13-10-2018 IPR036629 YjbJ superfamily CLOST_0408 eddb1fbb965b950067253cf7bb9241fa 65 Pfam PF05532 CsbD-like 4 56 1.5E-15 T 13-10-2018 IPR008462 CsbD-like domain CLOST_0408 eddb1fbb965b950067253cf7bb9241fa 65 Gene3D G3DSA:1.10.1470.10 1 65 1.0E-23 T 13-10-2018 IPR036629 YjbJ superfamily CLOST_1820 db61c1cd27c4a793ad79255065e6eafc 204 Gene3D G3DSA:2.60.120.10 11 116 1.6E-13 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_1820 db61c1cd27c4a793ad79255065e6eafc 204 Pfam PF05962 HutD 11 179 4.4E-22 T 13-10-2018 IPR010282 Uncharacterised protein family HutD/Ves CLOST_1820 db61c1cd27c4a793ad79255065e6eafc 204 SUPERFAMILY SSF51182 4 138 1.07E-24 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_2372 6b727a5f47ca67c3871cebe8c99dd93e 243 Pfam PF13309 HTH domain 179 239 6.7E-22 T 13-10-2018 IPR039445 Transcriptional regulator DauR-like, HTH domain CLOST_2372 6b727a5f47ca67c3871cebe8c99dd93e 243 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 4 111 5.0E-27 T 13-10-2018 IPR013559 YheO-like CLOST_2372 6b727a5f47ca67c3871cebe8c99dd93e 243 Pfam PF08348 YheO-like PAS domain 7 120 5.3E-40 T 13-10-2018 IPR013559 YheO-like CLOST_0028 92b320aaa354aa9c67fdd420b6cf34ba 218 SUPERFAMILY SSF161098 20 204 3.27E-36 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0028 92b320aaa354aa9c67fdd420b6cf34ba 218 Gene3D G3DSA:1.10.3720.10 16 214 3.7E-29 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0028 92b320aaa354aa9c67fdd420b6cf34ba 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 212 1.8E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_1821 fd7972d56239fe999b20ed56f990227e 98 SUPERFAMILY SSF52038 3 88 7.32E-15 T 13-10-2018 IPR035905 Barstar-like superfamily CLOST_1821 fd7972d56239fe999b20ed56f990227e 98 Pfam PF01337 Barstar (barnase inhibitor) 8 85 2.0E-14 T 13-10-2018 IPR000468 Barstar (barnase inhibitor) CLOST_1821 fd7972d56239fe999b20ed56f990227e 98 Gene3D G3DSA:3.30.370.10 4 90 8.3E-20 T 13-10-2018 IPR035905 Barstar-like superfamily CLOST_1765 38cb4bd8a40bee2f3da503c979311ffb 144 Gene3D G3DSA:3.30.70.260 66 143 9.2E-6 T 13-10-2018 CLOST_1765 38cb4bd8a40bee2f3da503c979311ffb 144 Pfam PF01842 ACT domain 68 113 1.4E-6 T 13-10-2018 IPR002912 ACT domain CLOST_1765 38cb4bd8a40bee2f3da503c979311ffb 144 PIRSF PIRSF025624 1 144 1.7E-50 T 13-10-2018 IPR008310 UPF0735 ACT domain-containing protein CLOST_1765 38cb4bd8a40bee2f3da503c979311ffb 144 SUPERFAMILY SSF55021 66 140 2.55E-10 T 13-10-2018 CLOST_1765 38cb4bd8a40bee2f3da503c979311ffb 144 Hamap MF_00707 UPF0735 ACT domain-containing protein . 1 144 29.647 T 13-10-2018 IPR008310 UPF0735 ACT domain-containing protein CLOST_2418 fc99a3be4efb1d0429731572cbd0c3c4 250 SUPERFAMILY SSF55073 95 245 2.67E-44 T 13-10-2018 IPR029787 Nucleotide cyclase CLOST_2418 fc99a3be4efb1d0429731572cbd0c3c4 250 Gene3D G3DSA:3.30.70.270 79 247 5.1E-51 T 13-10-2018 CLOST_2418 fc99a3be4efb1d0429731572cbd0c3c4 250 Pfam PF00990 Diguanylate cyclase, GGDEF domain 90 243 2.0E-43 T 13-10-2018 IPR000160 GGDEF domain CLOST_2418 fc99a3be4efb1d0429731572cbd0c3c4 250 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 89 245 8.2E-51 T 13-10-2018 IPR000160 GGDEF domain CLOST_2418 fc99a3be4efb1d0429731572cbd0c3c4 250 SMART SM00267 79 247 7.0E-55 T 13-10-2018 IPR000160 GGDEF domain CLOST_2076 04c9bce3aae8f26c756450dd147e59f2 190 Pfam PF12952 Domain of unknown function (DUF3841) 6 185 1.9E-62 T 13-10-2018 IPR024211 Protein of unknown function DUF3841 CLOST_1699 ed44d8f84a0ef6c8adda835db02d5871 258 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 213 239 - T 13-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CLOST_1699 ed44d8f84a0ef6c8adda835db02d5871 258 Pfam PF01148 Cytidylyltransferase family 2 254 3.0E-62 T 13-10-2018 CLOST_1220 38d64754f87702d543dc8aba278ae93a 44 Gene3D G3DSA:3.40.30.10 1 40 3.2E-10 T 13-10-2018 CLOST_1220 38d64754f87702d543dc8aba278ae93a 44 SUPERFAMILY SSF52833 1 41 8.2E-8 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_1220 38d64754f87702d543dc8aba278ae93a 44 Pfam PF03960 ArsC family 1 37 5.4E-8 T 13-10-2018 IPR006660 Arsenate reductase-like CLOST_1145 fbb015011b8c7e33ada1b7eeb6df9184 764 Pfam PF01136 Peptidase family U32 78 301 2.0E-81 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CLOST_1145 fbb015011b8c7e33ada1b7eeb6df9184 764 Pfam PF12392 Collagenase 384 498 1.2E-20 T 13-10-2018 IPR020988 Peptidase U32, collagenase CLOST_1898 65e0d155735215f14cb0154d5c55eb29 322 ProSitePatterns PS01348 MraY family signature 2. 169 180 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1898 65e0d155735215f14cb0154d5c55eb29 322 ProSitePatterns PS01347 MraY family signature 1. 51 63 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1898 65e0d155735215f14cb0154d5c55eb29 322 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 8 322 21.807 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1898 65e0d155735215f14cb0154d5c55eb29 322 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 22 320 9.4E-96 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1898 65e0d155735215f14cb0154d5c55eb29 322 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 51 63 9.9E-6 T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1898 65e0d155735215f14cb0154d5c55eb29 322 Pfam PF00953 Glycosyl transferase family 4 82 249 3.0E-36 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CLOST_1474 3e7a0f5c7487de8df9da7ae71577019b 62 SUPERFAMILY SSF54862 3 61 1.17E-16 T 13-10-2018 CLOST_1474 3e7a0f5c7487de8df9da7ae71577019b 62 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CLOST_1474 3e7a0f5c7487de8df9da7ae71577019b 62 Gene3D G3DSA:3.30.70.20 1 30 2.7E-6 T 13-10-2018 CLOST_1474 3e7a0f5c7487de8df9da7ae71577019b 62 Gene3D G3DSA:3.30.70.20 31 62 1.5E-6 T 13-10-2018 CLOST_1474 3e7a0f5c7487de8df9da7ae71577019b 62 Pfam PF13187 4Fe-4S dicluster domain 12 57 4.3E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1360 1ef7fd82ccb3f06ed78423bcfdf33710 170 Gene3D G3DSA:3.40.30.10 2 168 1.0E-42 T 13-10-2018 CLOST_1360 1ef7fd82ccb3f06ed78423bcfdf33710 170 Pfam PF08534 Redoxin 23 163 6.1E-18 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CLOST_1360 1ef7fd82ccb3f06ed78423bcfdf33710 170 ProSitePatterns PS01265 Tpx family signature. 87 98 - T 13-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 CLOST_1360 1ef7fd82ccb3f06ed78423bcfdf33710 170 SUPERFAMILY SSF52833 7 164 6.78E-37 T 13-10-2018 IPR036249 Thioredoxin-like superfamily CLOST_0827 0db0de18dbe921e4cfea8c7b3d98724f 579 Gene3D G3DSA:1.10.569.10 245 423 5.9E-62 T 13-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 CLOST_0827 0db0de18dbe921e4cfea8c7b3d98724f 579 SUPERFAMILY SSF56228 2 209 3.66E-51 T 13-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CLOST_0827 0db0de18dbe921e4cfea8c7b3d98724f 579 SUPERFAMILY SSF48310 214 574 1.83E-92 T 13-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CLOST_0827 0db0de18dbe921e4cfea8c7b3d98724f 579 SMART SM00790 1 208 1.9E-74 T 13-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CLOST_0827 0db0de18dbe921e4cfea8c7b3d98724f 579 Gene3D G3DSA:1.10.599.10 244 559 5.9E-62 T 13-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 CLOST_0827 0db0de18dbe921e4cfea8c7b3d98724f 579 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 3 206 8.8E-56 T 13-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CLOST_0827 0db0de18dbe921e4cfea8c7b3d98724f 579 Gene3D G3DSA:3.60.9.10 1 212 1.1E-56 T 13-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CLOST_0827 0db0de18dbe921e4cfea8c7b3d98724f 579 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 227 560 4.8E-66 T 13-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CLOST_0985 ddb77912aabbad0110e6cb4cc55bb3a9 363 Pfam PF00155 Aminotransferase class I and II 51 353 6.5E-31 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_0985 ddb77912aabbad0110e6cb4cc55bb3a9 363 SUPERFAMILY SSF53383 10 358 3.54E-57 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0985 ddb77912aabbad0110e6cb4cc55bb3a9 363 Gene3D G3DSA:3.90.1150.10 32 353 1.4E-86 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0985 ddb77912aabbad0110e6cb4cc55bb3a9 363 Gene3D G3DSA:3.40.640.10 42 261 1.4E-86 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1209 02e395be90e35950c5dcd611d1d6cbeb 428 SUPERFAMILY SSF53649 7 415 3.66E-67 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CLOST_1209 02e395be90e35950c5dcd611d1d6cbeb 428 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 12 374 1.3E-44 T 13-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CLOST_1854 6f4218412c96068a360db4eccfbcf38b 171 PIRSF PIRSF006594 2 167 1.0E-46 T 13-10-2018 IPR002829 Protein of unknown function DUF116 CLOST_1854 6f4218412c96068a360db4eccfbcf38b 171 Pfam PF01976 Protein of unknown function DUF116 14 164 2.4E-52 T 13-10-2018 IPR002829 Protein of unknown function DUF116 CLOST_0585 523b6115b68b7ac49d4f30513560ba06 544 PIRSF PIRSF002741 1 544 5.3E-122 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CLOST_0585 523b6115b68b7ac49d4f30513560ba06 544 Gene3D G3DSA:3.90.76.10 73 194 1.8E-186 T 13-10-2018 CLOST_0585 523b6115b68b7ac49d4f30513560ba06 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 467 8.4E-100 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain CLOST_0585 523b6115b68b7ac49d4f30513560ba06 544 Gene3D G3DSA:3.40.190.10 45 526 1.8E-186 T 13-10-2018 CLOST_0585 523b6115b68b7ac49d4f30513560ba06 544 Gene3D G3DSA:3.10.105.10 296 515 1.8E-186 T 13-10-2018 CLOST_0585 523b6115b68b7ac49d4f30513560ba06 544 SUPERFAMILY SSF53850 35 540 3.65E-141 T 13-10-2018 CLOST_1853 1dfe503d64828ad10dba7562f7f6eb8d 229 Pfam PF04298 Putative neutral zinc metallopeptidase 9 223 3.4E-92 T 13-10-2018 IPR007395 Putative neutral zinc metallopeptidase CLOST_0596 afd2302653b980315b8de3c6fae90ebd 231 Pfam PF05949 Bacterial protein of unknown function (DUF881) 88 228 1.6E-31 T 13-10-2018 IPR010273 Protein of unknown function DUF881 CLOST_0596 afd2302653b980315b8de3c6fae90ebd 231 Gene3D G3DSA:3.30.70.1880 86 231 2.6E-28 T 13-10-2018 CLOST_1006 207ad361ca4ebf3fa2553df6465a2f22 387 Pfam PF12683 Protein of unknown function (DUF3798) 42 313 8.8E-129 T 13-10-2018 IPR024258 Protein of unknown function DUF3798 CLOST_1006 207ad361ca4ebf3fa2553df6465a2f22 387 Gene3D G3DSA:3.40.50.11390 153 317 8.5E-71 T 13-10-2018 CLOST_2348 8547418a484661220fdb9c292cbe33c6 304 Gene3D G3DSA:1.20.1330.10 40 250 2.8E-53 T 13-10-2018 CLOST_2348 8547418a484661220fdb9c292cbe33c6 304 SUPERFAMILY SSF64518 1 304 6.02E-58 T 13-10-2018 CLOST_2348 8547418a484661220fdb9c292cbe33c6 304 Pfam PF00700 Bacterial flagellin C-terminal helical region 222 303 2.4E-5 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOST_2348 8547418a484661220fdb9c292cbe33c6 304 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 9.7E-18 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOST_2348 8547418a484661220fdb9c292cbe33c6 304 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 189 6.2E-42 T 13-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CLOST_1881 d5364afbfe139825bfeb0543aee960b3 231 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 6 227 28.857 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 CLOST_1881 d5364afbfe139825bfeb0543aee960b3 231 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 228 1.5E-54 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 CLOST_1881 d5364afbfe139825bfeb0543aee960b3 231 SUPERFAMILY SSF51419 1 226 1.38E-70 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_1881 d5364afbfe139825bfeb0543aee960b3 231 Pfam PF01168 Alanine racemase, N-terminal domain 20 228 1.7E-21 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_1881 d5364afbfe139825bfeb0543aee960b3 231 Gene3D G3DSA:3.20.20.10 1 231 6.0E-78 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_1881 d5364afbfe139825bfeb0543aee960b3 231 PIRSF PIRSF004848 1 231 3.3E-76 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 CLOST_0129 559ea0afb9d7e0f821b82b98bbc63818 288 SMART SM00729 15 233 4.0E-30 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CLOST_0129 559ea0afb9d7e0f821b82b98bbc63818 288 Gene3D G3DSA:3.20.20.70 14 274 5.7E-17 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0129 559ea0afb9d7e0f821b82b98bbc63818 288 SUPERFAMILY SSF102114 5 234 3.14E-39 T 13-10-2018 CLOST_0129 559ea0afb9d7e0f821b82b98bbc63818 288 Pfam PF04055 Radical SAM superfamily 20 172 2.1E-13 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_1737 3de214a9b6a7d41182892bff6eaad5e2 146 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 4 139 3.9E-26 T 13-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CLOST_1737 3de214a9b6a7d41182892bff6eaad5e2 146 Pfam PF02050 Flagellar FliJ protein 19 139 2.3E-18 T 13-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CLOST_0098 80e99d8065dea8f8f7fe6b8e0c7a2b36 751 ProSitePatterns PS01276 Peptidase family U32 signature. 163 181 - T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CLOST_0098 80e99d8065dea8f8f7fe6b8e0c7a2b36 751 Pfam PF01136 Peptidase family U32 78 291 1.5E-70 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CLOST_0098 80e99d8065dea8f8f7fe6b8e0c7a2b36 751 Pfam PF01136 Peptidase family U32 580 721 4.0E-9 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CLOST_0098 80e99d8065dea8f8f7fe6b8e0c7a2b36 751 Pfam PF12392 Collagenase 378 491 4.4E-18 T 13-10-2018 IPR020988 Peptidase U32, collagenase CLOST_1040 0eabb2bf210a9b9e271f4ca8564a104e 363 Gene3D G3DSA:3.40.50.10690 122 363 1.1E-92 T 13-10-2018 CLOST_1040 0eabb2bf210a9b9e271f4ca8564a104e 363 Gene3D G3DSA:2.40.420.10 15 103 4.8E-14 T 13-10-2018 CLOST_1658 4b87c5868fb0446d1e0a24805e3580ac 244 Pfam PF02811 PHP domain 10 186 2.8E-11 T 13-10-2018 IPR004013 PHP domain GO:0003824 CLOST_1658 4b87c5868fb0446d1e0a24805e3580ac 244 Gene3D G3DSA:3.20.20.140 2 244 1.7E-56 T 13-10-2018 CLOST_1658 4b87c5868fb0446d1e0a24805e3580ac 244 SMART SM00481 9 87 3.1E-11 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CLOST_1658 4b87c5868fb0446d1e0a24805e3580ac 244 SUPERFAMILY SSF89550 9 241 1.15E-45 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CLOST_0364 a57dab40788a3d6e57fc48be8260052d 387 Gene3D G3DSA:3.90.1150.10 266 387 7.1E-22 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0364 a57dab40788a3d6e57fc48be8260052d 387 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 6 369 9.2E-151 T 13-10-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family CLOST_0364 a57dab40788a3d6e57fc48be8260052d 387 SUPERFAMILY SSF53383 5 386 2.42E-105 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0364 a57dab40788a3d6e57fc48be8260052d 387 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 384 6.2E-96 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_0364 a57dab40788a3d6e57fc48be8260052d 387 Gene3D G3DSA:3.40.640.10 1 265 7.5E-90 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0364 a57dab40788a3d6e57fc48be8260052d 387 PIRSF PIRSF000390 1 387 1.1E-98 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_1827 b08bccda8289201d8d97703fea13cbbb 315 Pfam PF01497 Periplasmic binding protein 67 289 4.7E-35 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain CLOST_1827 b08bccda8289201d8d97703fea13cbbb 315 Gene3D G3DSA:3.40.50.1980 151 314 1.5E-43 T 13-10-2018 CLOST_1827 b08bccda8289201d8d97703fea13cbbb 315 SUPERFAMILY SSF53807 44 313 9.81E-69 T 13-10-2018 CLOST_1827 b08bccda8289201d8d97703fea13cbbb 315 Gene3D G3DSA:3.40.50.1980 42 150 1.5E-24 T 13-10-2018 CLOST_1294 5ef0d4c2ce166ba38bec32d78770559c 353 SUPERFAMILY SSF51735 2 143 9.44E-14 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1294 5ef0d4c2ce166ba38bec32d78770559c 353 Gene3D G3DSA:3.40.50.720 1 157 1.5E-27 T 13-10-2018 CLOST_0633 6081da8bb0cbd750227608877c6e7c0a 105 SUPERFAMILY SSF51182 14 102 1.75E-15 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0633 6081da8bb0cbd750227608877c6e7c0a 105 Gene3D G3DSA:2.60.120.10 1 105 2.8E-24 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_1571 1f52bc689bac923e0d9162ebd7be07e1 92 Gene3D G3DSA:3.40.1690.10 8 89 1.7E-26 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CLOST_1571 1f52bc689bac923e0d9162ebd7be07e1 92 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 9 24 9.3E-5 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1571 1f52bc689bac923e0d9162ebd7be07e1 92 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 39 60 9.3E-5 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1571 1f52bc689bac923e0d9162ebd7be07e1 92 Pfam PF01312 FlhB HrpN YscU SpaS Family 10 83 3.1E-23 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CLOST_1571 1f52bc689bac923e0d9162ebd7be07e1 92 SUPERFAMILY SSF160544 9 86 8.89E-25 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CLOST_2342 2f9eb08aac0a595f922ecfc3be393613 321 Gene3D G3DSA:3.40.50.720 4 321 9.2E-94 T 13-10-2018 CLOST_2342 2f9eb08aac0a595f922ecfc3be393613 321 SUPERFAMILY SSF51735 5 318 4.44E-81 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_2342 2f9eb08aac0a595f922ecfc3be393613 321 Pfam PF16363 GDP-mannose 4,6 dehydratase 8 312 3.2E-59 T 13-10-2018 IPR016040 NAD(P)-binding domain CLOST_0727 ffedfd817b67028380ca3742bba93412 244 Gene3D G3DSA:3.30.110.170 42 210 1.0E-13 T 13-10-2018 CLOST_0727 ffedfd817b67028380ca3742bba93412 244 Pfam PF04402 Protein of unknown function (DUF541) 40 241 1.3E-23 T 13-10-2018 IPR007497 Protein of unknown function DUF541 CLOST_0727 ffedfd817b67028380ca3742bba93412 244 Gene3D G3DSA:3.30.70.2970 52 165 1.0E-13 T 13-10-2018 CLOST_0727 ffedfd817b67028380ca3742bba93412 244 PIRSF PIRSF029033 1 244 2.9E-30 T 13-10-2018 IPR016907 Uncharacterised conserved protein UCP029033, periplasmic protein CLOST_1534 350e72ac1ba19dea132074e82b9d3b33 160 SUPERFAMILY SSF88659 82 139 8.04E-7 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_1534 350e72ac1ba19dea132074e82b9d3b33 160 Pfam PF08281 Sigma-70, region 4 86 136 5.0E-6 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOST_1534 350e72ac1ba19dea132074e82b9d3b33 160 Gene3D G3DSA:1.20.140.160 30 142 5.3E-6 T 13-10-2018 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 SMART SM00283 390 665 4.8E-64 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 SMART SM00304 309 361 2.8E-11 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 SUPERFAMILY SSF58104 329 665 9.81E-67 T 13-10-2018 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 Gene3D G3DSA:1.10.287.950 366 665 5.4E-62 T 13-10-2018 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 Gene3D G3DSA:3.30.450.20 182 280 5.8E-36 T 13-10-2018 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 466 618 2.6E-36 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 Gene3D G3DSA:1.10.8.500 308 360 4.1E-5 T 13-10-2018 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 Pfam PF00672 HAMP domain 311 356 4.8E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 SUPERFAMILY SSF103190 114 192 9.42E-8 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 Gene3D G3DSA:3.30.450.20 95 181 5.8E-36 T 13-10-2018 CLOST_0234 a0b17c2a04fa12eefda5a151b3b950c8 667 Pfam PF02743 Cache domain 35 271 1.4E-33 T 13-10-2018 IPR033479 Double Cache domain 1 CLOST_2053 17e6a4238ec88649b7ccca9dce410e51 500 SUPERFAMILY SSF52091 390 474 6.67E-10 T 13-10-2018 IPR036513 STAS domain superfamily CLOST_2053 17e6a4238ec88649b7ccca9dce410e51 500 Pfam PF01740 STAS domain 392 476 4.0E-9 T 13-10-2018 IPR002645 STAS domain CLOST_2053 17e6a4238ec88649b7ccca9dce410e51 500 Gene3D G3DSA:3.30.750.24 384 474 1.2E-16 T 13-10-2018 IPR036513 STAS domain superfamily CLOST_2053 17e6a4238ec88649b7ccca9dce410e51 500 Pfam PF00916 Sulfate permease family 147 345 4.4E-41 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CLOST_2053 17e6a4238ec88649b7ccca9dce410e51 500 Pfam PF00916 Sulfate permease family 14 139 7.9E-26 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CLOST_1254 6df80e566e8a5c0fa2b9a8224c40cfa2 316 Gene3D G3DSA:3.30.457.10 53 134 8.1E-18 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_1254 6df80e566e8a5c0fa2b9a8224c40cfa2 316 SUPERFAMILY SSF55383 51 137 3.73E-23 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_1254 6df80e566e8a5c0fa2b9a8224c40cfa2 316 Pfam PF07833 Copper amine oxidase N-terminal domain 49 136 3.1E-25 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_1254 6df80e566e8a5c0fa2b9a8224c40cfa2 316 Pfam PF07833 Copper amine oxidase N-terminal domain 30 78 1.5E-9 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_0565 490bc6d8a3bda3dae94594d2302809f0 189 Pfam PF01966 HD domain 24 96 2.6E-5 T 13-10-2018 IPR006674 HD domain CLOST_0565 490bc6d8a3bda3dae94594d2302809f0 189 SUPERFAMILY SSF109604 3 115 3.66E-11 T 13-10-2018 CLOST_0565 490bc6d8a3bda3dae94594d2302809f0 189 TIGRFAM TIGR00277 HDIG: HDIG domain 21 91 9.1E-8 T 13-10-2018 IPR006675 HDIG domain CLOST_0565 490bc6d8a3bda3dae94594d2302809f0 189 Gene3D G3DSA:1.10.3210.10 5 175 2.3E-7 T 13-10-2018 CLOST_1416 fbcea3354682de1ad4da8ca30eed6130 353 Gene3D G3DSA:3.90.1010.20 62 204 1.9E-9 T 13-10-2018 CLOST_1416 fbcea3354682de1ad4da8ca30eed6130 353 Gene3D G3DSA:3.90.1010.20 220 353 2.0E-9 T 13-10-2018 CLOST_1471 3b66284582a7727fc4aaa7b405e88703 176 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 171 4.8E-28 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CLOST_1471 3b66284582a7727fc4aaa7b405e88703 176 Gene3D G3DSA:3.40.920.10 1 176 7.6E-53 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1471 3b66284582a7727fc4aaa7b405e88703 176 SUPERFAMILY SSF53323 2 175 3.01E-30 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CLOST_1105 c2838a88994c1e6c3947dc9096dcd588 151 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 150 3.3E-58 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 CLOST_1105 c2838a88994c1e6c3947dc9096dcd588 151 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 1 148 31.824 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 CLOST_1105 c2838a88994c1e6c3947dc9096dcd588 151 Gene3D G3DSA:3.40.1280.10 1 151 5.2E-62 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CLOST_1105 c2838a88994c1e6c3947dc9096dcd588 151 Pfam PF00588 SpoU rRNA Methylase family 1 139 1.1E-34 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CLOST_1105 c2838a88994c1e6c3947dc9096dcd588 151 SUPERFAMILY SSF75217 1 149 1.18E-39 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases CLOST_1105 c2838a88994c1e6c3947dc9096dcd588 151 PIRSF PIRSF029256 1 151 5.0E-61 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 CLOST_1621 3f54c1d82200842413133adf8f5f8872 319 SUPERFAMILY SSF51735 1 314 4.33E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily CLOST_1621 3f54c1d82200842413133adf8f5f8872 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 241 7.0E-27 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CLOST_1621 3f54c1d82200842413133adf8f5f8872 319 Gene3D G3DSA:3.40.50.720 1 317 1.0E-104 T 13-10-2018 CLOST_0821 81619ec6fef9b1b5b906e302227340d9 49 Pfam PF13165 Six-cysteine peptide SCIFF 3 45 2.0E-24 T 13-10-2018 IPR023975 Six-cysteine peptide SCIFF CLOST_0821 81619ec6fef9b1b5b906e302227340d9 49 TIGRFAM TIGR03973 six_Cys_in_45: six-cysteine peptide SCIFF 3 45 4.3E-25 T 13-10-2018 IPR023975 Six-cysteine peptide SCIFF CLOST_2060 5e8a9e01044310597c2ca0f1196839a8 357 SMART SM00471 130 266 4.4E-7 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_2060 5e8a9e01044310597c2ca0f1196839a8 357 Pfam PF01966 HD domain 134 257 7.0E-15 T 13-10-2018 IPR006674 HD domain CLOST_2060 5e8a9e01044310597c2ca0f1196839a8 357 Gene3D G3DSA:1.10.3210.10 3 297 1.9E-65 T 13-10-2018 CLOST_2060 5e8a9e01044310597c2ca0f1196839a8 357 SUPERFAMILY SSF109604 130 294 3.66E-30 T 13-10-2018 CLOST_2310 b426495a0cc3b5f67580f38e6d00b1de 287 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 282 2.0E-84 T 13-10-2018 IPR003797 DegV CLOST_2310 b426495a0cc3b5f67580f38e6d00b1de 287 SUPERFAMILY SSF82549 1 283 3.4E-86 T 13-10-2018 CLOST_2310 b426495a0cc3b5f67580f38e6d00b1de 287 Gene3D G3DSA:3.30.1180.10 155 286 8.9E-39 T 13-10-2018 CLOST_2310 b426495a0cc3b5f67580f38e6d00b1de 287 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 281 1.9E-92 T 13-10-2018 IPR003797 DegV CLOST_2310 b426495a0cc3b5f67580f38e6d00b1de 287 Gene3D G3DSA:3.40.50.10170 2 151 4.0E-43 T 13-10-2018 CLOST_2049 355134c78137f49010e36e98e299a073 111 Gene3D G3DSA:1.20.58.1000 10 110 5.6E-37 T 13-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily CLOST_2049 355134c78137f49010e36e98e299a073 111 Pfam PF02583 Metal-sensitive transcriptional repressor 29 105 5.0E-31 T 13-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CLOST_0825 6498a1697b56a1a9475c5ad6353b7d68 74 Pfam PF02597 ThiS family 5 74 5.0E-13 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 CLOST_0825 6498a1697b56a1a9475c5ad6353b7d68 74 SUPERFAMILY SSF54285 1 72 1.29E-14 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CLOST_0825 6498a1697b56a1a9475c5ad6353b7d68 74 Gene3D G3DSA:3.10.20.30 1 74 5.2E-14 T 13-10-2018 IPR012675 Beta-grasp domain superfamily CLOST_1862 914d6d2c85c5fb94f24ecdff67b2a7a2 290 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 290 7.8E-76 T 13-10-2018 IPR005229 Conserved hypothetical protein CHP00255 CLOST_1862 914d6d2c85c5fb94f24ecdff67b2a7a2 290 Pfam PF03755 YicC-like family, N-terminal region 1 152 1.0E-39 T 13-10-2018 IPR013527 YicC-like, N-terminal CLOST_1862 914d6d2c85c5fb94f24ecdff67b2a7a2 290 Pfam PF08340 Domain of unknown function (DUF1732) 206 290 8.7E-35 T 13-10-2018 IPR013551 Domain of unknown function DUF1732 CLOST_1028 175a07c3846a0a7dbc2a43a28edf8a67 269 SUPERFAMILY SSF51219 7 240 1.2E-80 T 13-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily CLOST_1028 175a07c3846a0a7dbc2a43a28edf8a67 269 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 16 230 1.1E-29 T 13-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CLOST_1028 175a07c3846a0a7dbc2a43a28edf8a67 269 Gene3D G3DSA:3.60.160.10 1 254 1.1E-101 T 13-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily CLOST_1028 175a07c3846a0a7dbc2a43a28edf8a67 269 Pfam PF01987 Mitochondrial biogenesis AIM24 9 228 4.5E-68 T 13-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CLOST_0229 b82b87ac3b4246cbad103ce86b3995c9 109 Pfam PF12986 Domain of unknown function (DUF3870) 8 100 1.9E-34 T 13-10-2018 IPR024617 Domain of unknown function DUF3870 CLOST_2343 69ed31d448afaa04e8fdbd0f0f340d89 459 SUPERFAMILY SSF53756 157 459 2.25E-21 T 13-10-2018 CLOST_2343 69ed31d448afaa04e8fdbd0f0f340d89 459 SUPERFAMILY SSF48452 16 83 4.62E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_2343 69ed31d448afaa04e8fdbd0f0f340d89 459 Gene3D G3DSA:3.40.50.2000 301 459 2.3E-12 T 13-10-2018 CLOST_2343 69ed31d448afaa04e8fdbd0f0f340d89 459 Gene3D G3DSA:1.25.40.10 7 119 1.3E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CLOST_1187 56170ccd4ce5682269dcc8fe4df017c0 528 Pfam PF00361 Proton-conducting membrane transporter 120 397 1.9E-57 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1187 56170ccd4ce5682269dcc8fe4df017c0 528 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 156 180 4.3E-10 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1187 56170ccd4ce5682269dcc8fe4df017c0 528 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 228 252 4.3E-10 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_1187 56170ccd4ce5682269dcc8fe4df017c0 528 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 313 332 4.3E-10 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CLOST_0071 32f2328f61a8cd3471b81fe1d913af50 154 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 3.9E-24 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CLOST_0071 32f2328f61a8cd3471b81fe1d913af50 154 SUPERFAMILY SSF53927 2 146 1.06E-45 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CLOST_0071 32f2328f61a8cd3471b81fe1d913af50 154 Gene3D G3DSA:3.40.140.10 1 154 5.1E-60 T 13-10-2018 CLOST_0666 60b8455db2aa401f12e01884377e6bc0 268 Pfam PF06966 Protein of unknown function (DUF1295) 30 257 5.8E-75 T 13-10-2018 IPR010721 Protein of unknown function DUF1295 CLOST_0666 60b8455db2aa401f12e01884377e6bc0 268 Gene3D G3DSA:1.20.120.1630 67 264 3.4E-13 T 13-10-2018 CLOST_1033 73bafbe06f5a5340432157e4f884c27d 1212 SUPERFAMILY SSF52540 62 340 6.07E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0492 1903cb65e875f2b97fb6629c19b7200d 249 Gene3D G3DSA:3.40.50.970 63 242 2.4E-21 T 13-10-2018 CLOST_0492 1903cb65e875f2b97fb6629c19b7200d 249 SUPERFAMILY SSF52518 15 243 1.26E-56 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_0492 1903cb65e875f2b97fb6629c19b7200d 249 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 209 3.8E-24 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CLOST_0817 ea3479e2307608ba1dd4507eae508e09 163 Pfam PF01695 IstB-like ATP binding protein 58 159 5.9E-25 T 13-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CLOST_0817 ea3479e2307608ba1dd4507eae508e09 163 SUPERFAMILY SSF52540 68 155 4.14E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0817 ea3479e2307608ba1dd4507eae508e09 163 Gene3D G3DSA:3.40.50.300 64 163 1.1E-16 T 13-10-2018 CLOST_0307 c30c0e80f2eba7d950db561b270ddab2 390 Pfam PF03235 Protein of unknown function DUF262 26 221 1.2E-8 T 13-10-2018 IPR004919 Domain of unknown function DUF262 CLOST_2024 07e2e8d01bc5a3af19aff5abc7c580b6 231 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 4 212 1.1E-48 T 13-10-2018 IPR018708 Protein of unknown function DUF2225 CLOST_1089 f21fdaa1356b98ece7a69dccd6e83bcb 264 PIRSF PIRSF019254 1 264 3.0E-89 T 13-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CLOST_1089 f21fdaa1356b98ece7a69dccd6e83bcb 264 Gene3D G3DSA:3.30.2320.10 133 259 2.1E-77 T 13-10-2018 CLOST_1089 f21fdaa1356b98ece7a69dccd6e83bcb 264 Gene3D G3DSA:3.30.2400.30 3 253 2.1E-77 T 13-10-2018 CLOST_1089 f21fdaa1356b98ece7a69dccd6e83bcb 264 Pfam PF04454 Encapsulating protein for peroxidase 1 250 1.3E-77 T 13-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CLOST_1077 87e84416949e5a703c770597d816e4ea 233 SUPERFAMILY SSF52172 3 137 3.56E-26 T 13-10-2018 IPR011006 CheY-like superfamily CLOST_1077 87e84416949e5a703c770597d816e4ea 233 Pfam PF00072 Response regulator receiver domain 4 112 1.9E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1077 87e84416949e5a703c770597d816e4ea 233 Gene3D G3DSA:3.40.50.2300 1 125 4.0E-28 T 13-10-2018 CLOST_1077 87e84416949e5a703c770597d816e4ea 233 SMART SM00850 134 232 2.4E-30 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CLOST_1077 87e84416949e5a703c770597d816e4ea 233 SMART SM00448 1 112 1.8E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CLOST_1077 87e84416949e5a703c770597d816e4ea 233 Pfam PF04397 LytTr DNA-binding domain 135 231 7.4E-28 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CLOST_1077 87e84416949e5a703c770597d816e4ea 233 Gene3D G3DSA:2.40.50.40 126 194 3.4E-14 T 13-10-2018 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.1E-47 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 Pfam PF00453 Ribosomal protein L20 3 109 4.6E-46 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 68 8.0E-16 T 13-10-2018 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 Gene3D G3DSA:1.10.720.90 2 55 5.6E-21 T 13-10-2018 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.5E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.5E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.5E-38 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 SUPERFAMILY SSF74731 3 117 8.24E-47 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 Gene3D G3DSA:1.10.1900.20 56 119 2.0E-30 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1131 bc4951035564bb4b106979ff821e6aad 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.901 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2279 6124419cfc212ff47fbd91e67a7023dc 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 242 3.8E-14 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_2279 6124419cfc212ff47fbd91e67a7023dc 254 Gene3D G3DSA:1.10.3720.10 53 249 1.7E-20 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_2279 6124419cfc212ff47fbd91e67a7023dc 254 SUPERFAMILY SSF161098 56 238 1.7E-21 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0725 d1fca8ffe41a44f99149996c458880a8 82 SUPERFAMILY SSF143120 4 77 7.98E-16 T 13-10-2018 IPR036165 YefM-like superfamily CLOST_0725 d1fca8ffe41a44f99149996c458880a8 82 Gene3D G3DSA:3.40.1620.40 3 67 1.5E-21 T 13-10-2018 CLOST_0725 d1fca8ffe41a44f99149996c458880a8 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 69 1.2E-10 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CLOST_1891 6711c1dc11d0eefc1d18639a79d452f8 123 PIRSF PIRSF018579 1 113 3.9E-40 T 13-10-2018 IPR009709 Protein of unknown function DUF1290 CLOST_1891 6711c1dc11d0eefc1d18639a79d452f8 123 Pfam PF06947 Protein of unknown function (DUF1290) 23 107 7.1E-38 T 13-10-2018 IPR009709 Protein of unknown function DUF1290 CLOST_0795 ae22341cf1b89d22d5ab8daedc69a042 318 Pfam PF12385 Papain-like cysteine protease AvrRpt2 216 274 5.8E-4 T 13-10-2018 IPR022118 Peptidase C70, AvrRpt2 CLOST_0182 73828cd2beae8b6b28eb7c4060a7953b 122 SUPERFAMILY SSF54913 7 112 1.78E-6 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CLOST_2345 94cd570f13b24eed45283de12240acc9 272 SUPERFAMILY SSF64518 1 272 5.36E-91 T 13-10-2018 CLOST_2345 94cd570f13b24eed45283de12240acc9 272 Pfam PF00700 Bacterial flagellin C-terminal helical region 187 271 1.1E-29 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOST_2345 94cd570f13b24eed45283de12240acc9 272 PRINTS PR00207 Flagellin signature 109 132 4.4E-21 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOST_2345 94cd570f13b24eed45283de12240acc9 272 PRINTS PR00207 Flagellin signature 35 52 4.4E-21 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOST_2345 94cd570f13b24eed45283de12240acc9 272 PRINTS PR00207 Flagellin signature 74 93 4.4E-21 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CLOST_2345 94cd570f13b24eed45283de12240acc9 272 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 141 7.7E-44 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CLOST_2345 94cd570f13b24eed45283de12240acc9 272 Gene3D G3DSA:1.20.1330.10 48 223 4.6E-66 T 13-10-2018 CLOST_2345 94cd570f13b24eed45283de12240acc9 272 Gene3D G3DSA:1.10.8.410 224 272 1.3E-26 T 13-10-2018 CLOST_0344 13bf6a940a3751a5de6bb57108ce56aa 126 Pfam PF04977 Septum formation initiator 40 119 3.6E-14 T 13-10-2018 IPR007060 Septum formation initiator FtsL/DivIC CLOST_0059 720e479b27a10662f0d2af26258097f0 221 Pfam PF14282 FlxA-like protein 22 104 5.7E-9 T 13-10-2018 IPR025577 FlxA-like protein CLOST_0820 9bcfcb7acb28074d78ab6f556e255527 98 Gene3D G3DSA:3.30.70.1060 1 93 2.2E-20 T 13-10-2018 CLOST_0820 9bcfcb7acb28074d78ab6f556e255527 98 Pfam PF03795 YCII-related domain 1 90 6.2E-10 T 13-10-2018 IPR005545 YCII-related CLOST_0820 9bcfcb7acb28074d78ab6f556e255527 98 SUPERFAMILY SSF54909 2 91 6.97E-17 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel CLOST_1289 21b4bccd3ebcf58d487692b956d75525 465 TIGRFAM TIGR01319 glmL_fam: conserved hypothetical protein 10 449 8.4E-88 T 13-10-2018 IPR006230 Protein MutL CLOST_1289 21b4bccd3ebcf58d487692b956d75525 465 Pfam PF13941 MutL protein 5 448 5.2E-169 T 13-10-2018 IPR006230 Protein MutL CLOST_1289 21b4bccd3ebcf58d487692b956d75525 465 PIRSF PIRSF004729 2 452 5.5E-155 T 13-10-2018 IPR006230 Protein MutL CLOST_2384 9c65665e8555cd687f1b13244b0155e2 476 Pfam PF03553 Na+/H+ antiporter family 163 456 1.1E-63 T 13-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CLOST_2384 9c65665e8555cd687f1b13244b0155e2 476 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 8 460 2.5E-152 T 13-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CLOST_2300 af59c030a1f1f096149114ef8256482f 153 Gene3D G3DSA:3.40.630.30 5 152 8.7E-41 T 13-10-2018 CLOST_2300 af59c030a1f1f096149114ef8256482f 153 Pfam PF00583 Acetyltransferase (GNAT) family 17 125 7.6E-17 T 13-10-2018 IPR000182 GNAT domain CLOST_2300 af59c030a1f1f096149114ef8256482f 153 SUPERFAMILY SSF55729 4 148 1.93E-30 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2300 af59c030a1f1f096149114ef8256482f 153 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 145 1.1E-41 T 13-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CLOST_1573 a354cab033cd9ce6cf9cf2e172994b05 256 Gene3D G3DSA:3.30.420.10 44 256 5.0E-77 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_1573 a354cab033cd9ce6cf9cf2e172994b05 256 Pfam PF01351 Ribonuclease HII 77 252 2.2E-37 T 13-10-2018 IPR024567 Ribonuclease HII/HIII domain CLOST_1573 a354cab033cd9ce6cf9cf2e172994b05 256 SUPERFAMILY SSF53098 64 251 4.86E-64 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1573 a354cab033cd9ce6cf9cf2e172994b05 256 Hamap MF_00052_B Ribonuclease HII [rnhB]. 74 254 34.862 T 13-10-2018 IPR022898 Ribonuclease HII GO:0004523 CLOST_0726 dd9f34612ea4e043d3a750f4d5c13959 87 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 21 85 4.4E-10 T 13-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CLOST_0726 dd9f34612ea4e043d3a750f4d5c13959 87 SUPERFAMILY SSF143011 1 86 9.55E-20 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily CLOST_0726 dd9f34612ea4e043d3a750f4d5c13959 87 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 6 85 6.0E-25 T 13-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CLOST_0726 dd9f34612ea4e043d3a750f4d5c13959 87 Gene3D G3DSA:3.30.2310.20 2 85 1.8E-14 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily CLOST_0726 dd9f34612ea4e043d3a750f4d5c13959 87 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 3 85 9.9E-8 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CLOST_1288 d779d22d48193911c4ca7677b8ed71cf 353 Gene3D G3DSA:3.20.20.10 9 220 2.5E-24 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_1288 d779d22d48193911c4ca7677b8ed71cf 353 SUPERFAMILY SSF51419 7 228 5.76E-25 T 13-10-2018 IPR029066 PLP-binding barrel CLOST_1288 d779d22d48193911c4ca7677b8ed71cf 353 Pfam PF01168 Alanine racemase, N-terminal domain 7 222 7.6E-21 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CLOST_0316 66761770d0c31072c46489d2a7714a61 881 Pfam PF13240 zinc-ribbon domain 2 22 5.8E-6 T 13-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CLOST_0584 aa62eca64ba44f216e141a56dd6484d2 329 SUPERFAMILY SSF52540 9 259 2.13E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0584 aa62eca64ba44f216e141a56dd6484d2 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 326 2.9E-29 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0584 aa62eca64ba44f216e141a56dd6484d2 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 306 2.8E-18 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CLOST_0584 aa62eca64ba44f216e141a56dd6484d2 329 Pfam PF00005 ABC transporter 37 187 8.4E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_0584 aa62eca64ba44f216e141a56dd6484d2 329 Gene3D G3DSA:3.40.50.300 7 329 5.6E-108 T 13-10-2018 CLOST_0584 aa62eca64ba44f216e141a56dd6484d2 329 SMART SM00382 45 237 8.1E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_0584 aa62eca64ba44f216e141a56dd6484d2 329 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_0918 0f5451d3734115dcdcf720252ab7560e 262 Gene3D G3DSA:3.10.620.30 102 228 6.7E-12 T 13-10-2018 CLOST_0918 0f5451d3734115dcdcf720252ab7560e 262 SMART SM00460 163 219 2.3E-4 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0918 0f5451d3734115dcdcf720252ab7560e 262 Pfam PF01841 Transglutaminase-like superfamily 135 216 1.0E-7 T 13-10-2018 IPR002931 Transglutaminase-like CLOST_0918 0f5451d3734115dcdcf720252ab7560e 262 SUPERFAMILY SSF54001 115 230 2.07E-17 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_1072 6bbad6f783c5ff58276687ec7e979aba 240 Gene3D G3DSA:3.40.50.880 1 240 1.5E-72 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_1072 6bbad6f783c5ff58276687ec7e979aba 240 SUPERFAMILY SSF52317 31 239 1.85E-35 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like CLOST_1072 6bbad6f783c5ff58276687ec7e979aba 240 Pfam PF07722 Peptidase C26 3 219 4.6E-65 T 13-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CLOST_1219 a13bc1835d6c01c0b8e04e1d124c955b 457 Gene3D G3DSA:1.20.1740.10 7 457 3.7E-73 T 13-10-2018 CLOST_1219 a13bc1835d6c01c0b8e04e1d124c955b 457 Pfam PF13520 Amino acid permease 16 430 3.5E-43 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CLOST_1219 a13bc1835d6c01c0b8e04e1d124c955b 457 PIRSF PIRSF006060 1 457 2.4E-83 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CLOST_0884 4e174a22c4f360d84263d7d074b8a8a8 124 Pfam PF04519 Polymer-forming cytoskeletal 18 114 1.1E-25 T 13-10-2018 IPR007607 Bactofilin A/B CLOST_1960 7ad96459439bf4da13af2bd63bca4b6d 52 Gene3D G3DSA:3.30.2120.10 1 52 4.9E-6 T 13-10-2018 IPR028985 Bacillus phage protein-like CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 13-10-2018 IPR000241 Putative RNA methylase domain CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 SMART SM00981 57 155 0.0011 T 13-10-2018 IPR004114 THUMP domain GO:0003723 CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 194 208 2.1E-5 T 13-10-2018 CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 308 2.1E-5 T 13-10-2018 CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 299 305 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 Pfam PF01170 Putative RNA methylase family UPF0020 163 364 1.1E-52 T 13-10-2018 IPR000241 Putative RNA methylase domain CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 Pfam PF02926 THUMP domain 19 128 3.2E-7 T 13-10-2018 IPR004114 THUMP domain GO:0003723 CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 Gene3D G3DSA:3.40.50.150 161 364 5.0E-112 T 13-10-2018 CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 Gene3D G3DSA:3.30.2130.30 7 246 5.0E-112 T 13-10-2018 CLOST_1750 787ffaa7e1a3c09701d093e6879163c4 376 SUPERFAMILY SSF53335 148 372 1.41E-38 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_0247 e88eaa60d370511342dda2bde796ef8d 455 PIRSF PIRSF018788 1 455 4.4E-238 T 13-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CLOST_0247 e88eaa60d370511342dda2bde796ef8d 455 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 443 1.5E-215 T 13-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 CLOST_0247 e88eaa60d370511342dda2bde796ef8d 455 Gene3D G3DSA:3.20.20.70 142 454 2.4E-151 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_0247 e88eaa60d370511342dda2bde796ef8d 455 Gene3D G3DSA:2.30.170.30 1 54 2.8E-25 T 13-10-2018 CLOST_0247 e88eaa60d370511342dda2bde796ef8d 455 Gene3D G3DSA:1.10.220.70 55 141 6.7E-42 T 13-10-2018 CLOST_2089 09918a5fedf67991d45057559d2995ac 192 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 8 188 7.2E-48 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CLOST_2089 09918a5fedf67991d45057559d2995ac 192 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 8 188 2.9E-41 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CLOST_2089 09918a5fedf67991d45057559d2995ac 192 PIRSF PIRSF006806 3 191 1.3E-46 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CLOST_2089 09918a5fedf67991d45057559d2995ac 192 Gene3D G3DSA:3.40.50.10420 2 192 1.0E-57 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily CLOST_2089 09918a5fedf67991d45057559d2995ac 192 SUPERFAMILY SSF100950 7 192 2.51E-46 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_2587 024f3c805b3043c5227f5b6f8516f7a4 228 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 22 219 8.0E-69 T 13-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_2587 024f3c805b3043c5227f5b6f8516f7a4 228 Pfam PF02096 60Kd inner membrane protein 22 219 4.2E-65 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 CLOST_2587 024f3c805b3043c5227f5b6f8516f7a4 228 PRINTS PR01900 YidC translocation/secretion protein signature 7 23 4.9E-8 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 CLOST_2587 024f3c805b3043c5227f5b6f8516f7a4 228 PRINTS PR01900 YidC translocation/secretion protein signature 175 199 4.9E-8 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 CLOST_2587 024f3c805b3043c5227f5b6f8516f7a4 228 PRINTS PR01900 YidC translocation/secretion protein signature 153 168 4.9E-8 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 CLOST_1271 36de92b7a99700a901654b8d6f3662b6 126 Gene3D G3DSA:1.10.287.800 6 126 6.5E-24 T 13-10-2018 CLOST_1271 36de92b7a99700a901654b8d6f3662b6 126 Pfam PF11554 Protein of unknown function (DUF3232) 2 126 7.4E-55 T 13-10-2018 IPR021618 Protein of unknown function DUF3232 CLOST_1117 07df8cf187401701dbf2238affd566aa 349 Gene3D G3DSA:3.40.50.2300 149 336 7.4E-113 T 13-10-2018 CLOST_1117 07df8cf187401701dbf2238affd566aa 349 Gene3D G3DSA:3.40.50.2300 48 302 7.4E-113 T 13-10-2018 CLOST_1117 07df8cf187401701dbf2238affd566aa 349 SUPERFAMILY SSF53822 56 260 4.4E-13 T 13-10-2018 IPR028082 Periplasmic binding protein-like I CLOST_1117 07df8cf187401701dbf2238affd566aa 349 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 48 341 1.6E-87 T 13-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CLOST_1232 b660b00f49b03bc1f370c0361afb348d 334 SUPERFAMILY SSF56349 21 327 5.0E-46 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CLOST_1232 b660b00f49b03bc1f370c0361afb348d 334 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 28 109 1.0E-6 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CLOST_1232 b660b00f49b03bc1f370c0361afb348d 334 Gene3D G3DSA:1.10.150.130 15 128 1.5E-13 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal CLOST_1232 b660b00f49b03bc1f370c0361afb348d 334 Pfam PF00589 Phage integrase family 136 319 1.8E-40 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CLOST_1232 b660b00f49b03bc1f370c0361afb348d 334 Gene3D G3DSA:1.10.443.10 129 333 2.2E-47 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CLOST_1170 8ed44b4278654ecc5bd864b85d242a68 261 Pfam PF00809 Pterin binding enzyme 20 232 2.0E-29 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1170 8ed44b4278654ecc5bd864b85d242a68 261 Gene3D G3DSA:3.20.20.20 1 261 5.2E-75 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_1170 8ed44b4278654ecc5bd864b85d242a68 261 SUPERFAMILY SSF51717 4 260 1.57E-65 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 Gene3D G3DSA:3.30.420.40 10 305 1.2E-56 T 13-10-2018 CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 SUPERFAMILY SSF53067 8 129 7.77E-25 T 13-10-2018 CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 SMART SM00471 335 467 0.0017 T 13-10-2018 IPR003607 HD/PDEase domain CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 Gene3D G3DSA:1.10.3210.10 325 512 5.4E-38 T 13-10-2018 CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 SUPERFAMILY SSF109604 327 511 5.13E-41 T 13-10-2018 CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 Pfam PF02541 Ppx/GppA phosphatase family 22 310 5.9E-29 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 Gene3D G3DSA:3.30.420.150 113 298 1.2E-56 T 13-10-2018 CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 Pfam PF01966 HD domain 341 456 4.5E-11 T 13-10-2018 IPR006674 HD domain CLOST_0905 59b214cef40bdb08345b4744e76bf91c 513 SUPERFAMILY SSF53067 138 312 4.48E-19 T 13-10-2018 CLOST_1333 da1634f1f429ed5eef440234857906ea 293 SUPERFAMILY SSF56349 7 266 8.83E-28 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CLOST_1333 da1634f1f429ed5eef440234857906ea 293 Gene3D G3DSA:1.10.443.10 114 274 6.5E-33 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CLOST_1333 da1634f1f429ed5eef440234857906ea 293 Pfam PF00589 Phage integrase family 116 270 4.4E-29 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CLOST_1333 da1634f1f429ed5eef440234857906ea 293 Gene3D G3DSA:1.10.150.130 6 94 2.4E-6 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal CLOST_0607 a2ee40d7e85f4b18da1c02f2713c9135 136 Pfam PF01475 Ferric uptake regulator family 14 125 8.7E-16 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CLOST_0607 a2ee40d7e85f4b18da1c02f2713c9135 136 Gene3D G3DSA:3.30.1490.190 83 136 1.3E-10 T 13-10-2018 CLOST_0607 a2ee40d7e85f4b18da1c02f2713c9135 136 Gene3D G3DSA:1.10.10.10 2 81 1.1E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0607 a2ee40d7e85f4b18da1c02f2713c9135 136 SUPERFAMILY SSF46785 5 130 1.44E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_2396 fa9f4944f05985c143dd3cdac777d38f 362 Pfam PF09925 Predicted membrane protein (DUF2157) 25 155 4.7E-28 T 13-10-2018 IPR018677 Domain of unknown function DUF2157 CLOST_2309 91e3a366f78815e5ec6a2c6407c7f5f0 155 SUPERFAMILY SSF158397 36 155 4.45E-31 T 13-10-2018 IPR024042 TM1646-like domain superfamily CLOST_2309 91e3a366f78815e5ec6a2c6407c7f5f0 155 Pfam PF03885 Protein of unknown function (DUF327) 22 154 1.9E-37 T 13-10-2018 IPR005585 Protein of unknown function DUF327 CLOST_2309 91e3a366f78815e5ec6a2c6407c7f5f0 155 Gene3D G3DSA:1.20.120.490 34 154 4.1E-32 T 13-10-2018 IPR024042 TM1646-like domain superfamily CLOST_0155 11fee22eb8e398c6f88488ff19f428b1 102 SMART SM01078 2 96 5.5E-30 T 13-10-2018 IPR014925 Uncharacterised domain CGGC-dom CLOST_0155 11fee22eb8e398c6f88488ff19f428b1 102 Pfam PF08821 CGGC domain 2 74 1.2E-15 T 13-10-2018 IPR014925 Uncharacterised domain CGGC-dom CLOST_0973 1f0464aa3c13b7ec92b241279899edfb 114 Gene3D G3DSA:2.40.10.220 4 113 3.4E-6 T 13-10-2018 CLOST_0973 1f0464aa3c13b7ec92b241279899edfb 114 Pfam PF07238 PilZ domain 3 101 4.8E-8 T 13-10-2018 IPR009875 PilZ domain GO:0035438 CLOST_0973 1f0464aa3c13b7ec92b241279899edfb 114 SUPERFAMILY SSF141371 1 97 3.14E-6 T 13-10-2018 CLOST_1866 17a1ede1ceb55ee5006b1403b8b53a45 342 Gene3D G3DSA:1.20.1530.20 24 170 1.5E-5 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily CLOST_1866 17a1ede1ceb55ee5006b1403b8b53a45 342 Pfam PF03601 Conserved hypothetical protein 698 10 319 1.7E-79 T 13-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CLOST_0116 bfb885cdc0ef5b09f32dfc9f344f088c 70 Pfam PF07866 Protein of unknown function (DUF1653) 9 69 4.3E-30 T 13-10-2018 IPR023387 DUF1653-like domain CLOST_0116 bfb885cdc0ef5b09f32dfc9f344f088c 70 Gene3D G3DSA:2.30.30.320 2 70 6.7E-26 T 13-10-2018 IPR037135 DUF1653-like domain superfamily CLOST_2500 d65dc0beb7b29ee9c01a2f916967b16b 174 Gene3D G3DSA:1.20.120.450 1 170 5.8E-71 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CLOST_2500 d65dc0beb7b29ee9c01a2f916967b16b 174 Pfam PF08020 Protein of unknown function (DUF1706) 1 167 3.8E-58 T 13-10-2018 IPR012550 Protein of unknown function DUF1706 CLOST_2500 d65dc0beb7b29ee9c01a2f916967b16b 174 PIRSF PIRSF031551 1 171 5.8E-55 T 13-10-2018 IPR012550 Protein of unknown function DUF1706 CLOST_1564 b01d4f772a8a4a4655ce5df4e96187dc 274 Pfam PF02535 ZIP Zinc transporter 120 269 2.0E-19 T 13-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CLOST_0822 91c707f1c5f53bf477633e417555be3c 459 SUPERFAMILY SSF102114 91 412 2.49E-57 T 13-10-2018 CLOST_0822 91c707f1c5f53bf477633e417555be3c 459 Pfam PF13186 Iron-sulfur cluster-binding domain 341 403 1.0E-5 T 13-10-2018 IPR023885 4Fe4S-binding SPASM domain CLOST_0822 91c707f1c5f53bf477633e417555be3c 459 Pfam PF04055 Radical SAM superfamily 98 245 1.3E-12 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CLOST_0822 91c707f1c5f53bf477633e417555be3c 459 TIGRFAM TIGR03974 rSAM_six_Cys: SCIFF radical SAM maturase 2 446 5.6E-219 T 13-10-2018 IPR024025 SCIFF radical SAM maturase CLOST_0822 91c707f1c5f53bf477633e417555be3c 459 Pfam PF13353 4Fe-4S single cluster domain 93 227 7.4E-15 T 13-10-2018 CLOST_0822 91c707f1c5f53bf477633e417555be3c 459 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 341 427 8.4E-22 T 13-10-2018 IPR023885 4Fe4S-binding SPASM domain CLOST_0822 91c707f1c5f53bf477633e417555be3c 459 Gene3D G3DSA:3.20.20.70 88 449 2.1E-77 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_2367 31b4de2a99e46720e4b2351e6f9d5b98 234 Gene3D G3DSA:1.10.530.10 116 232 9.2E-17 T 13-10-2018 CLOST_2367 31b4de2a99e46720e4b2351e6f9d5b98 234 SUPERFAMILY SSF53955 117 201 1.5E-5 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily CLOST_2367 31b4de2a99e46720e4b2351e6f9d5b98 234 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 121 230 1.0E-18 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CLOST_2367 31b4de2a99e46720e4b2351e6f9d5b98 234 SMART SM00047 108 232 1.3E-5 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CLOST_0794 249930f764ae7f3403c07777aa112c45 159 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 7 154 2.8E-41 T 13-10-2018 IPR026353 Hypoxanthine-DNA glycosylase CLOST_0794 249930f764ae7f3403c07777aa112c45 159 Pfam PF03167 Uracil DNA glycosylase superfamily 11 155 9.7E-8 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_0794 249930f764ae7f3403c07777aa112c45 159 Gene3D G3DSA:3.40.470.10 3 159 2.4E-55 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_0794 249930f764ae7f3403c07777aa112c45 159 SUPERFAMILY SSF52141 7 159 7.06E-27 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CLOST_1351 10ebaf3cb04d51a9ad0ef5e3a0967f70 336 SUPERFAMILY SSF53659 1 331 2.59E-96 T 13-10-2018 CLOST_1351 10ebaf3cb04d51a9ad0ef5e3a0967f70 336 Gene3D G3DSA:3.40.718.10 1 335 3.8E-129 T 13-10-2018 CLOST_1351 10ebaf3cb04d51a9ad0ef5e3a0967f70 336 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 335 131.739 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CLOST_1351 10ebaf3cb04d51a9ad0ef5e3a0967f70 336 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 329 1.9E-107 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CLOST_1351 10ebaf3cb04d51a9ad0ef5e3a0967f70 336 PIRSF PIRSF002465 1 334 1.0E-119 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CLOST_1351 10ebaf3cb04d51a9ad0ef5e3a0967f70 336 Pfam PF02504 Fatty acid synthesis protein 1 318 2.3E-112 T 13-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CLOST_1493 9097d2b0ed30589ed8362dc152e07f86 140 Pfam PF01592 NifU-like N terminal domain 1 116 2.4E-48 T 13-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CLOST_1493 9097d2b0ed30589ed8362dc152e07f86 140 Gene3D G3DSA:3.90.1010.10 1 139 2.3E-57 T 13-10-2018 CLOST_1493 9097d2b0ed30589ed8362dc152e07f86 140 SUPERFAMILY SSF82649 1 116 2.12E-46 T 13-10-2018 CLOST_1493 9097d2b0ed30589ed8362dc152e07f86 140 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 1 115 3.9E-65 T 13-10-2018 IPR017787 NIF system FeS cluster assembly, NifU-like CLOST_0420 f01cdc26306bee9f630be4427ffb4a7e 165 Gene3D G3DSA:1.10.10.10 19 161 2.8E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_0420 f01cdc26306bee9f630be4427ffb4a7e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 8.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0420 f01cdc26306bee9f630be4427ffb4a7e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 133 153 8.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0420 f01cdc26306bee9f630be4427ffb4a7e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 8.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0420 f01cdc26306bee9f630be4427ffb4a7e 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 83 8.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0420 f01cdc26306bee9f630be4427ffb4a7e 165 Pfam PF01047 MarR family 57 108 7.1E-14 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0420 f01cdc26306bee9f630be4427ffb4a7e 165 SMART SM00347 41 143 8.3E-26 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CLOST_0420 f01cdc26306bee9f630be4427ffb4a7e 165 SUPERFAMILY SSF46785 24 157 1.27E-31 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1202 8acfc0446f61c5a697509159eb4119aa 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 281 2.2E-14 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_1202 8acfc0446f61c5a697509159eb4119aa 289 Gene3D G3DSA:1.10.3720.10 13 286 4.6E-49 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1202 8acfc0446f61c5a697509159eb4119aa 289 SUPERFAMILY SSF161098 15 280 7.59E-51 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0332 ff6b0685929e3ee220b1a019152395b0 443 Pfam PF00860 Permease family 28 403 4.0E-45 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 CLOST_0332 ff6b0685929e3ee220b1a019152395b0 443 PIRSF PIRSF005353 3 443 6.2E-179 T 13-10-2018 IPR026033 Purine permease PbuG-like CLOST_2229 8fb819664f49bcbd2b2ed0c965240af1 158 SUPERFAMILY SSF100950 33 98 9.21E-5 T 13-10-2018 IPR037171 NagB/RpiA transferase-like CLOST_2229 8fb819664f49bcbd2b2ed0c965240af1 158 Pfam PF09338 Glycine/sarcosine/betaine reductase component B subunits 6 100 4.0E-11 T 13-10-2018 IPR015417 Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta GO:0050485|GO:0055114 CLOST_0519 2a7471b78a972f5988ccf322625958a7 1160 Pfam PF00395 S-layer homology domain 1037 1080 5.0E-13 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0519 2a7471b78a972f5988ccf322625958a7 1160 Pfam PF00395 S-layer homology domain 1104 1147 4.0E-6 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0519 2a7471b78a972f5988ccf322625958a7 1160 Pfam PF00395 S-layer homology domain 980 1015 3.3E-4 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 Gene3D G3DSA:2.160.10.10 274 385 8.9E-26 T 13-10-2018 CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 Gene3D G3DSA:3.90.550.10 2 273 6.0E-92 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 190 200 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 358 4.8E-142 T 13-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 Pfam PF00483 Nucleotidyl transferase 8 258 5.4E-69 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 SUPERFAMILY SSF53448 2 339 1.64E-87 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 99 107 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 SUPERFAMILY SSF51161 265 375 1.91E-14 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 374 48.451 T 13-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 CLOST_0967 8fb6c79c6896b011e390aee191a73e86 400 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 327 358 9.8E-4 T 13-10-2018 IPR001451 Hexapeptide repeat CLOST_2273 42c17686d2fb7cf93790787b0da4a752 291 ProSitePatterns PS01215 Mrp family signature. 138 154 - T 13-10-2018 IPR000808 Mrp, conserved site GO:0005524 CLOST_2273 42c17686d2fb7cf93790787b0da4a752 291 SUPERFAMILY SSF52540 24 251 3.8E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2273 42c17686d2fb7cf93790787b0da4a752 291 Hamap MF_02040 Iron-sulfur cluster carrier protein. 24 269 35.092 T 13-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein CLOST_2273 42c17686d2fb7cf93790787b0da4a752 291 Gene3D G3DSA:3.40.50.300 22 268 2.9E-74 T 13-10-2018 CLOST_2273 42c17686d2fb7cf93790787b0da4a752 291 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 29 252 2.6E-91 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CLOST_1812 d6297c58558685808787a7fbe37871bd 353 Pfam PF00266 Aminotransferase class-V 23 320 4.7E-28 T 13-10-2018 IPR000192 Aminotransferase class V domain CLOST_1812 d6297c58558685808787a7fbe37871bd 353 PIRSF PIRSF000524 1 353 3.1E-77 T 13-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 CLOST_1812 d6297c58558685808787a7fbe37871bd 353 Gene3D G3DSA:3.90.1150.10 3 351 6.2E-102 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_1812 d6297c58558685808787a7fbe37871bd 353 Gene3D G3DSA:3.40.640.10 12 255 6.2E-102 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1812 d6297c58558685808787a7fbe37871bd 353 SUPERFAMILY SSF53383 3 352 1.1E-74 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0328 a19e4e9162365c57edc0514f440fefc5 281 Pfam PF04228 Putative neutral zinc metallopeptidase 1 276 1.4E-114 T 13-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CLOST_1513 6e6f3b56824864235f059714e2ee72f4 119 Gene3D G3DSA:3.10.450.40 1 118 1.2E-5 T 13-10-2018 CLOST_1513 6e6f3b56824864235f059714e2ee72f4 119 SUPERFAMILY SSF160719 18 107 9.94E-7 T 13-10-2018 CLOST_0119 f1847d275375238adccad4545a4362a3 304 Pfam PF06166 Protein of unknown function (DUF979) 7 304 2.9E-121 T 13-10-2018 IPR009323 Protein of unknown function DUF979 CLOST_1425 7dc92987cee3e1f9613fb5b969e956af 323 SMART SM00450 217 307 2.3E-10 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1425 7dc92987cee3e1f9613fb5b969e956af 323 SMART SM00450 72 167 1.6E-14 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1425 7dc92987cee3e1f9613fb5b969e956af 323 Pfam PF00581 Rhodanese-like domain 218 298 9.0E-11 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1425 7dc92987cee3e1f9613fb5b969e956af 323 Pfam PF00581 Rhodanese-like domain 74 159 3.8E-13 T 13-10-2018 IPR001763 Rhodanese-like domain CLOST_1425 7dc92987cee3e1f9613fb5b969e956af 323 Gene3D G3DSA:3.40.250.10 216 323 9.4E-22 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1425 7dc92987cee3e1f9613fb5b969e956af 323 Gene3D G3DSA:3.40.250.10 55 160 1.1E-21 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1425 7dc92987cee3e1f9613fb5b969e956af 323 SUPERFAMILY SSF52821 207 322 4.71E-21 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_1425 7dc92987cee3e1f9613fb5b969e956af 323 SUPERFAMILY SSF52821 53 159 8.91E-24 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily CLOST_0360 a4ba283053bf0c66a7b3ac16059842c0 605 SUPERFAMILY SSF56235 1 225 1.29E-60 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CLOST_0360 a4ba283053bf0c66a7b3ac16059842c0 605 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 522 1.2E-138 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CLOST_0360 a4ba283053bf0c66a7b3ac16059842c0 605 PIRSF PIRSF001589 1 603 1.8E-151 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CLOST_0360 a4ba283053bf0c66a7b3ac16059842c0 605 SUPERFAMILY SSF52402 238 581 1.31E-61 T 13-10-2018 CLOST_0360 a4ba283053bf0c66a7b3ac16059842c0 605 Pfam PF13537 Glutamine amidotransferase domain 51 168 1.9E-40 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain CLOST_0360 a4ba283053bf0c66a7b3ac16059842c0 605 Gene3D G3DSA:3.60.20.10 2 188 2.3E-60 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CLOST_0360 a4ba283053bf0c66a7b3ac16059842c0 605 Pfam PF00733 Asparagine synthase 241 588 6.4E-81 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CLOST_0440 c55cd9fb29780cfa2eeb2ce7c6b01954 364 SUPERFAMILY SSF52540 3 258 2.63E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0440 c55cd9fb29780cfa2eeb2ce7c6b01954 364 Gene3D G3DSA:3.40.50.300 8 283 1.1E-21 T 13-10-2018 CLOST_0440 c55cd9fb29780cfa2eeb2ce7c6b01954 364 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 128 256 4.0E-22 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CLOST_1060 7aa6033339800fd8838ebe481c562e92 94 Gene3D G3DSA:2.30.30.90 25 94 1.5E-9 T 13-10-2018 IPR038157 Ferrous iron transporter, core domain CLOST_1060 7aa6033339800fd8838ebe481c562e92 94 SUPERFAMILY SSF50037 27 94 8.7E-9 T 13-10-2018 IPR008988 Transcriptional repressor, C-terminal CLOST_1060 7aa6033339800fd8838ebe481c562e92 94 SMART SM00899 25 94 1.4E-6 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOST_1060 7aa6033339800fd8838ebe481c562e92 94 Pfam PF04023 FeoA domain 25 94 1.5E-10 T 13-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CLOST_1873 5cdb95d9b20bb59b5aaac917ebf04778 230 SUPERFAMILY SSF53167 3 228 6.68E-67 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 CLOST_1873 5cdb95d9b20bb59b5aaac917ebf04778 230 Gene3D G3DSA:3.40.50.1580 1 230 4.8E-67 T 13-10-2018 CLOST_1873 5cdb95d9b20bb59b5aaac917ebf04778 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 229 1.6E-59 T 13-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CLOST_1873 5cdb95d9b20bb59b5aaac917ebf04778 230 Pfam PF01048 Phosphorylase superfamily 3 228 1.0E-54 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CLOST_0382 96e8730d96425e2ce092d9befae9a68a 261 Gene3D G3DSA:3.30.457.10 52 129 3.9E-25 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0382 96e8730d96425e2ce092d9befae9a68a 261 SUPERFAMILY SSF55383 50 133 2.22E-25 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0382 96e8730d96425e2ce092d9befae9a68a 261 SUPERFAMILY SSF55383 20 63 3.53E-6 T 13-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily CLOST_0382 96e8730d96425e2ce092d9befae9a68a 261 Pfam PF07833 Copper amine oxidase N-terminal domain 47 132 2.2E-28 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_1181 0243a1aa8e98c91cfae7c9fe53fbaf2a 109 Pfam PF01899 Na+/H+ ion antiporter subunit 8 106 8.7E-17 T 13-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CLOST_1959 36775d8cc1123377297c82062104a5c5 256 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 35 253 5.5E-45 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase CLOST_1959 36775d8cc1123377297c82062104a5c5 256 Gene3D G3DSA:3.60.140.10 3 256 1.8E-54 T 13-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily CLOST_1959 36775d8cc1123377297c82062104a5c5 256 SUPERFAMILY SSF64438 12 253 1.08E-50 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CLOST_1350 827806c30ef0fbe92fe3484a5d9fcfec 121 Pfam PF03780 Asp23 family, cell envelope-related function 7 110 1.5E-35 T 13-10-2018 IPR005531 Alkaline shock protein Asp23 CLOST_1778 185aa552d9ea8f1fc5cef2caa33483c3 341 Pfam PF02562 PhoH-like protein 110 313 2.6E-96 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 CLOST_1778 185aa552d9ea8f1fc5cef2caa33483c3 341 SUPERFAMILY SSF54791 18 65 2.43E-5 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CLOST_1778 185aa552d9ea8f1fc5cef2caa33483c3 341 Gene3D G3DSA:3.40.50.300 107 313 9.6E-77 T 13-10-2018 CLOST_1778 185aa552d9ea8f1fc5cef2caa33483c3 341 SUPERFAMILY SSF52540 65 288 2.96E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 SUPERFAMILY SSF50104 1 112 1.7E-47 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 PRINTS PR00061 Ribosomal protein L19 signature 33 62 4.8E-42 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 PRINTS PR00061 Ribosomal protein L19 signature 3 32 4.8E-42 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 PRINTS PR00061 Ribosomal protein L19 signature 87 112 4.8E-42 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 Gene3D G3DSA:2.30.30.790 4 113 4.0E-14 T 13-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 2.4E-50 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 Pfam PF01245 Ribosomal protein L19 3 111 4.6E-51 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 PIRSF PIRSF002191 1 113 4.7E-50 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_1575 411b23a3562308db6769900fa49ef6c2 113 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 32.013 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CLOST_0239 186f077c20b260d4e624eb58328fb2a4 444 SUPERFAMILY SSF69318 70 294 5.23E-8 T 13-10-2018 CLOST_0269 01e238c6f1a9d585a4464deb34ced60c 231 Pfam PF02361 Cobalt transport protein 13 222 5.1E-39 T 13-10-2018 IPR003339 ABC/ECF transporter, transmembrane component CLOST_0269 01e238c6f1a9d585a4464deb34ced60c 231 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 17 218 3.5E-48 T 13-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 CLOST_1037 83573075f61c1aa8e9016de8ec9aef3d 839 Pfam PF08665 PglZ domain 452 626 4.6E-51 T 13-10-2018 IPR013973 PglZ domain CLOST_1037 83573075f61c1aa8e9016de8ec9aef3d 839 SUPERFAMILY SSF53649 445 630 1.45E-6 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CLOST_1037 83573075f61c1aa8e9016de8ec9aef3d 839 TIGRFAM TIGR02687 TIGR02687: TIGR02687 family protein 11 824 2.1E-165 T 13-10-2018 IPR014060 Conserved hypothetical protein CHP02687 CLOST_2093 689021b3475243a3087a5d0c4dc58df3 242 Pfam PF02361 Cobalt transport protein 6 208 3.1E-27 T 13-10-2018 IPR003339 ABC/ECF transporter, transmembrane component CLOST_1634 c7a8d73f7f5435dbe038771cf25df8c8 136 Pfam PF12120 Rifampin ADP-ribosyl transferase 11 108 4.7E-47 T 13-10-2018 IPR021975 Rifampin ADP-ribosyltransferase CLOST_1634 c7a8d73f7f5435dbe038771cf25df8c8 136 Gene3D G3DSA:3.20.170.40 1 136 3.0E-61 T 13-10-2018 IPR038611 Rifampin ADP-ribosyltransferase superfamily CLOST_1010 ad40459662fe09df012c1a083b2d85ff 424 Gene3D G3DSA:1.20.1530.20 8 403 1.4E-33 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily CLOST_1010 ad40459662fe09df012c1a083b2d85ff 424 Pfam PF00999 Sodium/hydrogen exchanger family 17 401 2.9E-53 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CLOST_2374 690997e9741a76e771cbf958a5093335 160 Pfam PF08281 Sigma-70, region 4 105 155 2.6E-12 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CLOST_2374 690997e9741a76e771cbf958a5093335 160 SUPERFAMILY SSF88946 6 92 1.18E-16 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_2374 690997e9741a76e771cbf958a5093335 160 SUPERFAMILY SSF88659 100 159 1.35E-13 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CLOST_2374 690997e9741a76e771cbf958a5093335 160 Gene3D G3DSA:1.10.10.10 96 160 8.8E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_2374 690997e9741a76e771cbf958a5093335 160 Pfam PF04542 Sigma-70 region 2 18 80 5.6E-12 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 CLOST_2374 690997e9741a76e771cbf958a5093335 160 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 158 1.2E-25 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 CLOST_2374 690997e9741a76e771cbf958a5093335 160 Gene3D G3DSA:1.10.1740.10 2 81 6.3E-17 T 13-10-2018 CLOST_0067 09a2a80618e66b6c948effc7379d861e 166 Gene3D G3DSA:3.40.50.300 64 164 2.4E-16 T 13-10-2018 CLOST_0067 09a2a80618e66b6c948effc7379d861e 166 SUPERFAMILY SSF52540 68 155 4.82E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0067 09a2a80618e66b6c948effc7379d861e 166 Pfam PF01695 IstB-like ATP binding protein 58 160 4.4E-25 T 13-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CLOST_1298 f05e36fbfb191dbd7b937b594f823af8 151 Pfam PF12821 Threonine/Serine exporter, ThrE 7 133 5.0E-39 T 13-10-2018 IPR024528 Threonine/Serine exporter, ThrE CLOST_1712 d449cc5e723b3c8eaf6e9d17adbfb4e8 207 Gene3D G3DSA:3.40.1550.10 7 204 5.3E-59 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_1712 d449cc5e723b3c8eaf6e9d17adbfb4e8 207 Pfam PF04509 CheC-like family 109 146 3.6E-11 T 13-10-2018 IPR007597 CheC-like protein GO:0016787 CLOST_1712 d449cc5e723b3c8eaf6e9d17adbfb4e8 207 Pfam PF04509 CheC-like family 13 46 7.3E-12 T 13-10-2018 IPR007597 CheC-like protein GO:0016787 CLOST_1712 d449cc5e723b3c8eaf6e9d17adbfb4e8 207 SUPERFAMILY SSF103039 6 203 2.62E-50 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_2400 6560d16cbdc57e97b58d2472778e84f0 149 SUPERFAMILY SSF55729 1 131 7.67E-18 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2400 6560d16cbdc57e97b58d2472778e84f0 149 Gene3D G3DSA:3.40.630.30 1 137 6.1E-20 T 13-10-2018 CLOST_2400 6560d16cbdc57e97b58d2472778e84f0 149 Pfam PF13508 Acetyltransferase (GNAT) domain 45 131 1.1E-10 T 13-10-2018 IPR000182 GNAT domain CLOST_1435 5ed275105b6b9f46fb196bc8570617dc 236 Pfam PF04143 Sulphur transport 72 234 9.3E-35 T 13-10-2018 IPR007272 Sulphur transport domain CLOST_0491 7df793fefffb2eeec291dfbed807d5bb 351 SUPERFAMILY SSF52922 238 349 7.07E-26 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_0491 7df793fefffb2eeec291dfbed807d5bb 351 SUPERFAMILY SSF52518 1 235 8.34E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_0491 7df793fefffb2eeec291dfbed807d5bb 351 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 247 336 4.3E-24 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CLOST_0491 7df793fefffb2eeec291dfbed807d5bb 351 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 192 3.0E-51 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CLOST_0491 7df793fefffb2eeec291dfbed807d5bb 351 Gene3D G3DSA:3.40.50.970 1 191 3.6E-64 T 13-10-2018 CLOST_0491 7df793fefffb2eeec291dfbed807d5bb 351 Gene3D G3DSA:3.40.50.920 235 348 1.7E-24 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CLOST_1245 907fbbe1ad408254cd8a2bdc501a3f5a 308 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 98 2.9E-12 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CLOST_1245 907fbbe1ad408254cd8a2bdc501a3f5a 308 Gene3D G3DSA:1.10.443.10 116 307 2.8E-52 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CLOST_1245 907fbbe1ad408254cd8a2bdc501a3f5a 308 SUPERFAMILY SSF56349 13 300 5.89E-60 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CLOST_1245 907fbbe1ad408254cd8a2bdc501a3f5a 308 Gene3D G3DSA:1.10.150.130 12 111 2.3E-19 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal CLOST_1245 907fbbe1ad408254cd8a2bdc501a3f5a 308 Pfam PF00589 Phage integrase family 124 293 2.8E-39 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CLOST_0194 67c7455e53c662ca08a72cb5dc388438 115 Gene3D G3DSA:2.60.120.10 19 115 7.5E-13 T 13-10-2018 IPR014710 RmlC-like jelly roll fold CLOST_0194 67c7455e53c662ca08a72cb5dc388438 115 Pfam PF07883 Cupin domain 40 109 8.8E-8 T 13-10-2018 IPR013096 Cupin 2, conserved barrel CLOST_0194 67c7455e53c662ca08a72cb5dc388438 115 SUPERFAMILY SSF51182 27 113 1.42E-14 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily CLOST_0648 1d8b1ea24f261d2726c868cf15503962 679 PIRSF PIRSF001265 1 675 7.0E-282 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_0648 1d8b1ea24f261d2726c868cf15503962 679 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 1 667 26.525 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_0648 1d8b1ea24f261d2726c868cf15503962 679 Pfam PF03030 Inorganic H+ pyrophosphatase 12 662 5.7E-287 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_0648 1d8b1ea24f261d2726c868cf15503962 679 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 5 672 1.0E-271 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CLOST_2302 30d517c5df7a7f0f2dffe4fc3298a32d 150 Gene3D G3DSA:3.40.50.300 1 149 2.6E-43 T 13-10-2018 CLOST_2302 30d517c5df7a7f0f2dffe4fc3298a32d 150 SUPERFAMILY SSF52540 17 121 1.56E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2302 30d517c5df7a7f0f2dffe4fc3298a32d 150 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 4 134 1.3E-39 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CLOST_2302 30d517c5df7a7f0f2dffe4fc3298a32d 150 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 6 125 5.9E-39 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CLOST_2558 2b85b671e958396f962d69e5e1c090e1 429 SUPERFAMILY SSF158499 132 199 3.01E-5 T 13-10-2018 IPR034829 DnaD-like domain superfamily CLOST_2558 2b85b671e958396f962d69e5e1c090e1 429 SUPERFAMILY SSF158499 227 280 1.44E-12 T 13-10-2018 IPR034829 DnaD-like domain superfamily CLOST_2558 2b85b671e958396f962d69e5e1c090e1 429 Pfam PF07261 Replication initiation and membrane attachment 228 281 9.8E-11 T 13-10-2018 IPR006343 DnaD domain CLOST_2558 2b85b671e958396f962d69e5e1c090e1 429 Pfam PF07261 Replication initiation and membrane attachment 133 206 4.1E-11 T 13-10-2018 IPR006343 DnaD domain CLOST_2558 2b85b671e958396f962d69e5e1c090e1 429 Gene3D G3DSA:1.10.10.630 127 205 1.8E-8 T 13-10-2018 IPR034829 DnaD-like domain superfamily CLOST_2558 2b85b671e958396f962d69e5e1c090e1 429 Gene3D G3DSA:1.10.10.630 225 285 7.9E-10 T 13-10-2018 IPR034829 DnaD-like domain superfamily CLOST_2558 2b85b671e958396f962d69e5e1c090e1 429 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 234 280 1.4E-7 T 13-10-2018 IPR006343 DnaD domain CLOST_1215 8615e01fb805b2202a8e9d81c7f3f383 498 SUPERFAMILY SSF51445 11 495 2.11E-166 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily CLOST_1215 8615e01fb805b2202a8e9d81c7f3f383 498 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 10 494 8.5E-103 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CLOST_1215 8615e01fb805b2202a8e9d81c7f3f383 498 Pfam PF02446 4-alpha-glucanotransferase 17 476 1.3E-161 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CLOST_1215 8615e01fb805b2202a8e9d81c7f3f383 498 Gene3D G3DSA:3.20.20.80 8 498 2.7E-181 T 13-10-2018 CLOST_0149 fe24b7f22295c692c749660f05f9ecd0 170 Pfam PF01569 PAP2 superfamily 51 166 2.6E-25 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOST_0149 fe24b7f22295c692c749660f05f9ecd0 170 Gene3D G3DSA:1.20.144.10 1 83 3.1E-9 T 13-10-2018 CLOST_0149 fe24b7f22295c692c749660f05f9ecd0 170 Gene3D G3DSA:1.20.144.10 84 170 5.7E-22 T 13-10-2018 CLOST_0149 fe24b7f22295c692c749660f05f9ecd0 170 SMART SM00014 51 160 3.7E-22 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CLOST_0149 fe24b7f22295c692c749660f05f9ecd0 170 SUPERFAMILY SSF48317 2 166 1.31E-42 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily CLOST_0632 5fa6a25357f570adeb3c57dc7fc18ccf 166 Pfam PF03773 Predicted permease 29 161 3.1E-12 T 13-10-2018 IPR005524 Predicted permease DUF318 CLOST_0677 1786d6ed8d174212e0320a38e3144e47 108 SMART SM00877 5 84 2.0E-12 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0677 1786d6ed8d174212e0320a38e3144e47 108 SUPERFAMILY SSF143414 4 101 3.4E-20 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0677 1786d6ed8d174212e0320a38e3144e47 108 Pfam PF00936 BMC domain 6 84 7.0E-18 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0677 1786d6ed8d174212e0320a38e3144e47 108 Gene3D G3DSA:3.30.70.1710 5 99 1.3E-21 T 13-10-2018 CLOST_0677 1786d6ed8d174212e0320a38e3144e47 108 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 6 64 9.0E-6 T 13-10-2018 CLOST_1797 d6b296add2300459b119ddfe8dc39aea 232 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 23 227 1.9E-32 T 13-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CLOST_0662 4fec3725580d4f2459faf339ec27de17 99 Pfam PF03606 C4-dicarboxylate anaerobic carrier 24 57 2.2E-5 T 13-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CLOST_0369 3a04d3f659f0a1d25bf8abac0f40183d 233 Gene3D G3DSA:3.90.550.10 1 228 7.1E-74 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0369 3a04d3f659f0a1d25bf8abac0f40183d 233 SUPERFAMILY SSF53448 1 229 7.89E-55 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CLOST_0369 3a04d3f659f0a1d25bf8abac0f40183d 233 Pfam PF02348 Cytidylyltransferase 5 164 7.6E-31 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CLOST_1691 eaf2b545522429df28c0c3028ea66969 107 Gene3D G3DSA:3.30.1330.30 2 100 1.0E-33 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like CLOST_1691 eaf2b545522429df28c0c3028ea66969 107 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 94 1.6E-14 T 13-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CLOST_1691 eaf2b545522429df28c0c3028ea66969 107 SUPERFAMILY SSF55315 5 99 5.5E-25 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like CLOST_0299 d1db9b05e933c49f37398478da3c82d5 70 Pfam PF12728 Helix-turn-helix domain 5 36 3.0E-6 T 13-10-2018 CLOST_1483 9abad50ff482fd772573a7b73a302f9c 261 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 240 3.7E-26 T 13-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CLOST_2359 d843390f03a61ca0dff00a883b6d4bd5 309 Pfam PF03547 Membrane transport protein 160 304 2.9E-19 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CLOST_2359 d843390f03a61ca0dff00a883b6d4bd5 309 Pfam PF03547 Membrane transport protein 5 154 5.0E-22 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CLOST_0557 d92ca57c4ab9475b0327d00ae00724a8 210 SUPERFAMILY SSF56300 31 147 3.07E-10 T 13-10-2018 CLOST_0557 d92ca57c4ab9475b0327d00ae00724a8 210 Gene3D G3DSA:3.60.21.10 25 203 1.4E-8 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like CLOST_0557 d92ca57c4ab9475b0327d00ae00724a8 210 Pfam PF00149 Calcineurin-like phosphoesterase 32 121 6.2E-7 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CLOST_2077 74540e4df368e0429d5d7f5e5ecf5e38 250 Pfam PF08445 FR47-like protein 169 244 9.0E-12 T 13-10-2018 IPR013653 FR47-like GO:0016747 CLOST_2077 74540e4df368e0429d5d7f5e5ecf5e38 250 Gene3D G3DSA:3.40.630.30 115 236 6.5E-23 T 13-10-2018 CLOST_2077 74540e4df368e0429d5d7f5e5ecf5e38 250 SUPERFAMILY SSF55729 98 246 3.04E-12 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_1677 e8a1e7e4a00ead3249334761ee67b8dc 593 Pfam PF13245 AAA domain 208 352 2.9E-9 T 13-10-2018 CLOST_1677 e8a1e7e4a00ead3249334761ee67b8dc 593 Gene3D G3DSA:3.40.50.300 387 592 1.9E-22 T 13-10-2018 CLOST_1677 e8a1e7e4a00ead3249334761ee67b8dc 593 Gene3D G3DSA:3.40.50.300 188 386 5.0E-22 T 13-10-2018 CLOST_1677 e8a1e7e4a00ead3249334761ee67b8dc 593 SUPERFAMILY SSF52540 197 581 5.52E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_1677 e8a1e7e4a00ead3249334761ee67b8dc 593 Pfam PF13361 UvrD-like helicase C-terminal domain 382 474 2.1E-9 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CLOST_0105 63bb6fdf4aa4c8f17f2acc6ee6e9135a 211 Pfam PF00877 NlpC/P60 family 27 120 8.7E-14 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain CLOST_0105 63bb6fdf4aa4c8f17f2acc6ee6e9135a 211 Gene3D G3DSA:3.90.1720.10 7 147 5.6E-28 T 13-10-2018 CLOST_0105 63bb6fdf4aa4c8f17f2acc6ee6e9135a 211 SUPERFAMILY SSF54001 11 133 1.86E-23 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CLOST_1375 b2633551264a3285de9af7cf41245b5c 457 Gene3D G3DSA:2.40.50.140 30 105 3.4E-6 T 13-10-2018 CLOST_1375 b2633551264a3285de9af7cf41245b5c 457 Pfam PF10150 Ribonuclease E/G family 101 366 6.6E-68 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CLOST_0447 ecd873168c18f8ceea0eaff831fc1837 363 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 360 1.9E-117 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_0447 ecd873168c18f8ceea0eaff831fc1837 363 Gene3D G3DSA:3.40.640.10 6 243 2.3E-87 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0447 ecd873168c18f8ceea0eaff831fc1837 363 Gene3D G3DSA:3.90.1150.10 245 363 1.6E-37 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0447 ecd873168c18f8ceea0eaff831fc1837 363 SUPERFAMILY SSF53383 15 363 2.31E-116 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0447 ecd873168c18f8ceea0eaff831fc1837 363 PIRSF PIRSF000390 5 363 9.7E-102 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CLOST_0084 aa3f9ba956c0aefe00bbc6ee6c435bbf 274 SUPERFAMILY SSF161098 71 254 5.49E-28 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0084 aa3f9ba956c0aefe00bbc6ee6c435bbf 274 Gene3D G3DSA:1.10.3720.10 67 266 3.4E-22 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0084 aa3f9ba956c0aefe00bbc6ee6c435bbf 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 273 2.8E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_2123 26b863d93650399d05219a76b24b4752 122 Pfam PF03899 ATP synthase I chain 18 104 4.9E-8 T 13-10-2018 IPR005598 ATP synthase protein I CLOST_0298 f8c139d4e822ce15b17d65df6813df5c 144 Pfam PF01381 Helix-turn-helix 7 59 1.8E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_0298 f8c139d4e822ce15b17d65df6813df5c 144 Gene3D G3DSA:1.10.260.40 2 82 1.3E-17 T 13-10-2018 CLOST_0298 f8c139d4e822ce15b17d65df6813df5c 144 SUPERFAMILY SSF47413 2 63 1.07E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_0298 f8c139d4e822ce15b17d65df6813df5c 144 SMART SM00530 6 61 7.2E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_0011 2c040e8498277df89e0338cbe340a48f 150 SUPERFAMILY SSF55874 47 142 2.75E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0011 2c040e8498277df89e0338cbe340a48f 150 Gene3D G3DSA:3.30.565.10 17 147 8.8E-23 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CLOST_0011 2c040e8498277df89e0338cbe340a48f 150 Pfam PF13581 Histidine kinase-like ATPase domain 24 144 7.9E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CLOST_0995 62443c9cd6adc52eec8221bde0367684 247 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 1 240 1.0E-72 T 13-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CLOST_0995 62443c9cd6adc52eec8221bde0367684 247 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 1 243 1.0E-57 T 13-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CLOST_1779 daf05dae24014a1e29adbbffc448b8d2 124 Gene3D G3DSA:2.60.40.730 1 124 1.5E-37 T 13-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 CLOST_1779 daf05dae24014a1e29adbbffc448b8d2 124 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 9 121 1.7E-23 T 13-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 CLOST_1779 daf05dae24014a1e29adbbffc448b8d2 124 SUPERFAMILY SSF49367 7 121 1.31E-32 T 13-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 CLOST_1779 daf05dae24014a1e29adbbffc448b8d2 124 Pfam PF01880 Desulfoferrodoxin 11 117 5.2E-28 T 13-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 CLOST_2482 bcc5c680a1ba150877747ee91ac4b26b 174 Gene3D G3DSA:3.40.50.850 1 174 1.5E-24 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 CLOST_2482 bcc5c680a1ba150877747ee91ac4b26b 174 Pfam PF00857 Isochorismatase family 4 170 1.6E-16 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 CLOST_2482 bcc5c680a1ba150877747ee91ac4b26b 174 SUPERFAMILY SSF52499 1 170 2.49E-23 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 CLOST_0459 3955159a55307cf3c6cefe427c31a447 73 Pfam PF07872 Protein of unknown function (DUF1659) 9 45 7.5E-11 T 13-10-2018 IPR012454 Protein of unknown function DUF1659 CLOST_0461 a4b3420eaf387d4b4a767764eeeecb8c 641 Pfam PF00395 S-layer homology domain 167 213 2.3E-8 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0461 a4b3420eaf387d4b4a767764eeeecb8c 641 Pfam PF00395 S-layer homology domain 28 70 1.7E-13 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2332 3bc92d51686d30db79571f4e8c3f116b 535 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 12 122 2.0E-22 T 13-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CLOST_2332 3bc92d51686d30db79571f4e8c3f116b 535 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 228 523 1.4E-40 T 13-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 CLOST_0159 7c2c05c3a7002bdf192ac50bc3b6f99c 344 ProSitePatterns PS00112 Phosphagen kinase active site signature. 156 162 - T 13-10-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 CLOST_0159 7c2c05c3a7002bdf192ac50bc3b6f99c 344 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 45 242 1.5E-65 T 13-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 CLOST_0159 7c2c05c3a7002bdf192ac50bc3b6f99c 344 Hamap MF_00602 Protein-arginine kinase [mcsB]. 6 338 31.926 T 13-10-2018 IPR023660 Protein arginine kinase GO:0016775 CLOST_0159 7c2c05c3a7002bdf192ac50bc3b6f99c 344 SUPERFAMILY SSF55931 14 257 5.61E-77 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CLOST_0159 7c2c05c3a7002bdf192ac50bc3b6f99c 344 Gene3D G3DSA:3.30.590.10 2 250 8.3E-72 T 13-10-2018 CLOST_1012 9bf1bb9f00df8d674a37ad77dacb7b6b 424 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 1.3E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOST_1012 9bf1bb9f00df8d674a37ad77dacb7b6b 424 PRINTS PR00758 Arsenical pump membrane protein signature 362 387 1.3E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOST_1012 9bf1bb9f00df8d674a37ad77dacb7b6b 424 PRINTS PR00758 Arsenical pump membrane protein signature 395 419 1.3E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOST_1012 9bf1bb9f00df8d674a37ad77dacb7b6b 424 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 1.3E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOST_1012 9bf1bb9f00df8d674a37ad77dacb7b6b 424 PRINTS PR00758 Arsenical pump membrane protein signature 275 299 1.3E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOST_1012 9bf1bb9f00df8d674a37ad77dacb7b6b 424 PRINTS PR00758 Arsenical pump membrane protein signature 320 342 1.3E-13 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CLOST_1012 9bf1bb9f00df8d674a37ad77dacb7b6b 424 Pfam PF03600 Citrate transporter 19 366 1.7E-57 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CLOST_0834 58f834dec6520de2c5794dceb7ef6c6f 215 Pfam PF04117 Mpv17 / PMP22 family 169 206 2.9E-4 T 13-10-2018 IPR007248 Mpv17/PMP22 GO:0016021 CLOST_0608 727eaeea278d314263a80645a2165f8a 498 Pfam PF13682 Chemoreceptor zinc-binding domain 392 456 1.2E-10 T 13-10-2018 IPR025991 Chemoreceptor zinc-binding domain CLOST_0608 727eaeea278d314263a80645a2165f8a 498 Gene3D G3DSA:1.10.287.950 66 403 1.0E-51 T 13-10-2018 CLOST_0608 727eaeea278d314263a80645a2165f8a 498 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 175 324 4.3E-32 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0608 727eaeea278d314263a80645a2165f8a 498 SMART SM00283 98 367 1.0E-26 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 CLOST_0608 727eaeea278d314263a80645a2165f8a 498 SUPERFAMILY SSF58104 70 360 1.83E-49 T 13-10-2018 CLOST_1768 9456413a6bcf5d9c774ce09c9965130d 275 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 267 60.242 T 13-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CLOST_1768 9456413a6bcf5d9c774ce09c9965130d 275 Pfam PF03618 Kinase/pyrophosphorylase 6 262 4.7E-96 T 13-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CLOST_2158 0ac1ee713b0c255eeb8adffd76843155 139 Pfam PF04463 Protein of unknown function (DUF523) 3 136 6.7E-42 T 13-10-2018 IPR007553 Domain of unknown function DUF523 CLOST_0522 8562ef2a7f2056b2792a2cf021e41143 340 SUPERFAMILY SSF53383 4 318 2.61E-55 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0522 8562ef2a7f2056b2792a2cf021e41143 340 Gene3D G3DSA:3.40.640.10 28 237 3.1E-88 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_0522 8562ef2a7f2056b2792a2cf021e41143 340 Gene3D G3DSA:3.90.1150.10 5 317 3.1E-88 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CLOST_0522 8562ef2a7f2056b2792a2cf021e41143 340 Pfam PF00155 Aminotransferase class I and II 4 316 1.7E-41 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 PRINTS PR00297 10kDa chaperonin signature 59 71 4.1E-30 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 PRINTS PR00297 10kDa chaperonin signature 25 46 4.1E-30 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 PRINTS PR00297 10kDa chaperonin signature 3 18 4.1E-30 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 PRINTS PR00297 10kDa chaperonin signature 80 93 4.1E-30 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 13-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 SUPERFAMILY SSF50129 1 94 8.57E-33 T 13-10-2018 IPR011032 GroES-like superfamily CLOST_0285 93010fc587ee78fba7ed77e679663488 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 1.2E-33 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 Hamap MF_00580 10 kDa chaperonin [groS]. 2 94 25.368 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 Gene3D G3DSA:2.30.33.40 1 94 1.2E-36 T 13-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 CLOST_0285 93010fc587ee78fba7ed77e679663488 94 SMART SM00883 2 93 2.5E-51 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CLOST_2160 d72ed3cf96ccede1c35eea8c8feda2d9 70 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 38 3.4E-6 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CLOST_1826 575d762b798800036d57f8b5f04aedd4 350 Pfam PF01032 FecCD transport family 21 344 4.7E-101 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 CLOST_1826 575d762b798800036d57f8b5f04aedd4 350 SUPERFAMILY SSF81345 8 344 4.32E-85 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_1826 575d762b798800036d57f8b5f04aedd4 350 Gene3D G3DSA:1.10.3470.10 7 350 6.4E-109 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_2540 281959f713714cc393971998163a9ff7 140 Pfam PF04657 Putative inner membrane exporter, YdcZ 3 136 1.1E-30 T 13-10-2018 IPR006750 Putative inner membrane exporter, YdcZ CLOST_2175 01e64f92ce6c542910acf7e26df11ba7 95 Gene3D G3DSA:2.30.30.30 4 92 5.2E-6 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 CLOST_2175 01e64f92ce6c542910acf7e26df11ba7 95 SUPERFAMILY SSF50104 5 67 3.61E-11 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily CLOST_0878 a7332a97dad4f7c49372d8a5f316c4e3 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 325 7.0E-43 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_0878 a7332a97dad4f7c49372d8a5f316c4e3 330 SUPERFAMILY SSF161098 101 313 9.32E-17 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0878 a7332a97dad4f7c49372d8a5f316c4e3 330 Gene3D G3DSA:1.10.3720.10 93 321 1.0E-18 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0913 06241f7e184f73f6511c474052c36a42 295 Pfam PF01169 Uncharacterized protein family UPF0016 6 79 5.0E-21 T 13-10-2018 IPR001727 Gdt1 family CLOST_0913 06241f7e184f73f6511c474052c36a42 295 Pfam PF01169 Uncharacterized protein family UPF0016 106 180 1.4E-17 T 13-10-2018 IPR001727 Gdt1 family CLOST_2511 c9f980779fc6afaf542c0dd37dbf200d 354 Gene3D G3DSA:3.30.460.10 64 196 4.0E-6 T 13-10-2018 CLOST_2511 c9f980779fc6afaf542c0dd37dbf200d 354 SUPERFAMILY SSF81301 70 189 3.15E-7 T 13-10-2018 CLOST_1747 e075773235c22018265eb1ef337dbed0 280 Gene3D G3DSA:1.10.3720.10 4 274 1.6E-54 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1747 e075773235c22018265eb1ef337dbed0 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 264 2.2E-10 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_1747 e075773235c22018265eb1ef337dbed0 280 SUPERFAMILY SSF161098 5 271 1.07E-54 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_1054 7461dc4bd8cd0d312ab053e2a15f42d7 179 Gene3D G3DSA:3.90.960.10 13 179 8.1E-37 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 CLOST_1054 7461dc4bd8cd0d312ab053e2a15f42d7 179 SUPERFAMILY SSF55826 25 179 1.57E-28 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 CLOST_1054 7461dc4bd8cd0d312ab053e2a15f42d7 179 Pfam PF04073 Aminoacyl-tRNA editing domain 44 164 4.6E-19 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CLOST_1353 9dfd2f8149a9e925799ce8ba32777b24 167 Pfam PF02620 Uncharacterized ACR, COG1399 55 164 4.1E-19 T 13-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CLOST_2470 89582745e2d2be6e5029c9ce70e98803 185 Gene3D G3DSA:3.40.630.30 2 182 9.0E-37 T 13-10-2018 CLOST_2470 89582745e2d2be6e5029c9ce70e98803 185 Pfam PF13302 Acetyltransferase (GNAT) domain 55 154 1.7E-16 T 13-10-2018 IPR000182 GNAT domain CLOST_2470 89582745e2d2be6e5029c9ce70e98803 185 SUPERFAMILY SSF55729 4 178 6.34E-35 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_0142 60078517c330de3f8dd790bf1680b13b 85 Pfam PF04994 TfoX C-terminal domain 2 78 2.4E-23 T 13-10-2018 IPR007077 TfoX, C-terminal CLOST_0142 60078517c330de3f8dd790bf1680b13b 85 Gene3D G3DSA:1.10.150.20 1 85 1.1E-31 T 13-10-2018 CLOST_2575 604dc74773eb66d9d253797c89fa89c8 182 Pfam PF02674 Colicin V production protein 5 169 2.9E-16 T 13-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CLOST_0250 ee08fe50f10109098c22dd9025309635 168 SUPERFAMILY SSF143414 4 98 7.85E-28 T 13-10-2018 IPR037233 CcmK-like superfamily CLOST_0250 ee08fe50f10109098c22dd9025309635 168 SMART SM00877 4 80 1.9E-29 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0250 ee08fe50f10109098c22dd9025309635 168 Gene3D G3DSA:3.30.70.1710 1 110 1.8E-34 T 13-10-2018 CLOST_0250 ee08fe50f10109098c22dd9025309635 168 Pfam PF00936 BMC domain 5 80 7.3E-24 T 13-10-2018 IPR000249 Microcompartment protein, bacteria CLOST_0250 ee08fe50f10109098c22dd9025309635 168 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 47 2.0E-8 T 13-10-2018 CLOST_2081 aa841a8f31f242deeff8654ebf4bcdb1 157 Pfam PF10925 Protein of unknown function (DUF2680) 70 107 9.1E-7 T 13-10-2018 IPR024485 Protein of unknown function DUF2680 CLOST_1183 d5aa29193f5abb50e8ea5ff3def39344 97 Pfam PF13244 Domain of unknown function (DUF4040) 7 70 1.8E-18 T 13-10-2018 IPR025383 Domain of unknown function DUF4040 CLOST_1868 25a7c97c5147a8db5d403b9101470270 415 Pfam PF00860 Permease family 24 380 5.1E-80 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 CLOST_1868 25a7c97c5147a8db5d403b9101470270 415 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 328 348 - T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CLOST_1868 25a7c97c5147a8db5d403b9101470270 415 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 22 409 1.4E-92 T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CLOST_1975 17b7b1fef5d7b7014486c8009a4b97ab 639 Pfam PF03169 OPT oligopeptide transporter protein 34 593 1.7E-72 T 13-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CLOST_1446 5eefaaaea09d8b1cde9bbe5b3224c7ec 201 Pfam PF02589 LUD domain 4 190 2.3E-37 T 13-10-2018 IPR003741 LUD domain CLOST_2371 02ab51c574f3c7137d720cf03d11f872 450 Pfam PF03313 Serine dehydratase alpha chain 211 441 2.1E-50 T 13-10-2018 IPR005130 Serine dehydratase-like, alpha subunit CLOST_2371 02ab51c574f3c7137d720cf03d11f872 450 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 5 446 35.12 T 13-10-2018 IPR021144 Uncharacterised protein family UPF0597 CLOST_2371 02ab51c574f3c7137d720cf03d11f872 450 PIRSF PIRSF006054 3 448 1.4E-153 T 13-10-2018 IPR021144 Uncharacterised protein family UPF0597 CLOST_0631 e317990704bd114e110ace2836ae150a 160 Pfam PF03773 Predicted permease 36 159 1.0E-11 T 13-10-2018 IPR005524 Predicted permease DUF318 CLOST_2047 68f077ee9ecad9c9080dd60008efd554 82 Pfam PF04226 Transglycosylase associated protein 33 82 1.7E-14 T 13-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CLOST_1190 2aac2006bf79ccf0f12fa6ccb6631291 188 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 6 179 2.2E-13 T 13-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 CLOST_1190 2aac2006bf79ccf0f12fa6ccb6631291 188 PIRSF PIRSF021362 3 188 1.3E-52 T 13-10-2018 IPR009206 Nucleotidase, putative CLOST_1190 2aac2006bf79ccf0f12fa6ccb6631291 188 Gene3D G3DSA:1.10.40.40 17 66 7.7E-11 T 13-10-2018 CLOST_1190 2aac2006bf79ccf0f12fa6ccb6631291 188 SUPERFAMILY SSF56784 5 164 7.32E-21 T 13-10-2018 IPR036412 HAD-like superfamily CLOST_1190 2aac2006bf79ccf0f12fa6ccb6631291 188 Gene3D G3DSA:3.40.50.1000 6 178 7.7E-11 T 13-10-2018 IPR023214 HAD superfamily CLOST_1613 c1029f005c6916cbb376bfd1f6d2393a 165 Pfam PF07670 Nucleoside recognition 19 105 2.5E-6 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CLOST_2534 75ae94a05968529debc8d1ed2941814d 404 Pfam PF05977 Transmembrane secretion effector 9 398 9.0E-25 T 13-10-2018 IPR010290 Transmembrane secretion effector CLOST_2534 75ae94a05968529debc8d1ed2941814d 404 SUPERFAMILY SSF103473 3 395 4.19E-37 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_2534 75ae94a05968529debc8d1ed2941814d 404 Gene3D G3DSA:1.20.1250.20 2 181 3.3E-12 T 13-10-2018 CLOST_2534 75ae94a05968529debc8d1ed2941814d 404 Gene3D G3DSA:1.20.1250.20 212 403 1.6E-16 T 13-10-2018 CLOST_0581 49b4419ab1ba43fa0d69e44fc6a903de 307 Gene3D G3DSA:1.10.3720.10 86 301 1.8E-25 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0581 49b4419ab1ba43fa0d69e44fc6a903de 307 SUPERFAMILY SSF161098 88 291 1.96E-22 T 13-10-2018 IPR035906 MetI-like superfamily CLOST_0581 49b4419ab1ba43fa0d69e44fc6a903de 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 4.4E-44 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CLOST_1053 9d6be126f2d6f56bcf91f829cf5c95ad 215 Gene3D G3DSA:3.40.50.410 2 176 5.1E-9 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily CLOST_1053 9d6be126f2d6f56bcf91f829cf5c95ad 215 SUPERFAMILY SSF53300 7 151 2.08E-12 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily CLOST_0732 74167820925336e1f23862c319d4d6ee 112 ProDom PD052877 ARCHAEL AF0269 3 51 1.0E-9 T 13-10-2018 CLOST_2382 8f76c1895fa8d2d59845275d4d867ca1 206 Gene3D G3DSA:3.40.1550.10 1 200 4.8E-43 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_2382 8f76c1895fa8d2d59845275d4d867ca1 206 SUPERFAMILY SSF103039 1 200 2.09E-33 T 13-10-2018 IPR028976 CheC-like superfamily CLOST_0606 4289b9060cb1d7917aa62156f9e71470 263 Gene3D G3DSA:1.10.3470.10 50 263 2.2E-7 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_0606 4289b9060cb1d7917aa62156f9e71470 263 SUPERFAMILY SSF81345 3 257 1.44E-36 T 13-10-2018 IPR037294 ABC transporter, BtuC-like CLOST_0606 4289b9060cb1d7917aa62156f9e71470 263 Pfam PF00950 ABC 3 transport family 4 259 1.1E-69 T 13-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CLOST_1291 bf2e594ec9d33f78db8ce35fdc865ae0 121 Pfam PF16552 D-ornithine 4,5-aminomutase alpha-subunit 2 116 2.0E-58 T 13-10-2018 IPR015130 D-Lysine 5,6-aminomutase alpha subunit CLOST_1291 bf2e594ec9d33f78db8ce35fdc865ae0 121 Gene3D G3DSA:1.10.8.1000 45 121 3.6E-40 T 13-10-2018 CLOST_1291 bf2e594ec9d33f78db8ce35fdc865ae0 121 SUPERFAMILY SSF51703 17 116 7.53E-16 T 13-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CLOST_1241 99b50827fe702e21fc42c09ee51ee847 589 Gene3D G3DSA:3.40.50.410 394 586 1.5E-7 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily CLOST_1241 99b50827fe702e21fc42c09ee51ee847 589 SUPERFAMILY SSF53300 394 572 2.57E-9 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily CLOST_1783 09458e129edcbb540091248eadd77e62 336 Hamap MF_01562 UPF0365 protein . 4 324 48.281 T 13-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity CLOST_1783 09458e129edcbb540091248eadd77e62 336 Pfam PF12127 SigmaW regulon antibacterial 10 321 1.6E-166 T 13-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity CLOST_1998 2868a08cfc2fca795033ca7bb8c686be 305 Pfam PF04463 Protein of unknown function (DUF523) 12 150 1.3E-27 T 13-10-2018 IPR007553 Domain of unknown function DUF523 CLOST_0504 27eeafef8523d33ea516e2efc9899098 152 Gene3D G3DSA:1.20.120.520 1 141 3.1E-9 T 13-10-2018 CLOST_0504 27eeafef8523d33ea516e2efc9899098 152 Pfam PF01814 Hemerythrin HHE cation binding domain 3 117 2.2E-12 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CLOST_1286 b926debef3bd505bce504cb64ac6bd0f 109 Pfam PF03956 Lysine exporter LysO 11 96 6.1E-7 T 13-10-2018 IPR005642 Lysine exporter LysO CLOST_0915 bed7dcac0904c2529754ab324983ad88 272 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 268 17.985 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOST_0915 bed7dcac0904c2529754ab324983ad88 272 Pfam PF02673 Bacitracin resistance protein BacA 8 261 1.8E-86 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOST_0915 bed7dcac0904c2529754ab324983ad88 272 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 8 261 7.9E-76 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CLOST_2464 d58fbc672d564613711127d20b98d4ca 294 SUPERFAMILY SSF53807 26 288 3.27E-50 T 13-10-2018 CLOST_2464 d58fbc672d564613711127d20b98d4ca 294 Pfam PF01497 Periplasmic binding protein 44 267 1.4E-27 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain CLOST_2464 d58fbc672d564613711127d20b98d4ca 294 Gene3D G3DSA:3.40.50.1980 126 294 1.7E-59 T 13-10-2018 CLOST_2464 d58fbc672d564613711127d20b98d4ca 294 Gene3D G3DSA:3.40.50.1980 36 125 4.3E-24 T 13-10-2018 CLOST_1188 90f77a329cad2bdf0a1789e9eb1787d8 381 SUPERFAMILY SSF53335 156 286 1.31E-14 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CLOST_1188 90f77a329cad2bdf0a1789e9eb1787d8 381 Gene3D G3DSA:3.40.50.150 148 279 4.8E-11 T 13-10-2018 CLOST_1188 90f77a329cad2bdf0a1789e9eb1787d8 381 Pfam PF13679 Methyltransferase domain 154 291 8.4E-35 T 13-10-2018 IPR025714 Methyltransferase domain CLOST_1272 c741329eab4a2aad934418b13e00773e 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 8 57 1.0E-9 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CLOST_1272 c741329eab4a2aad934418b13e00773e 82 SUPERFAMILY SSF143120 8 54 6.28E-9 T 13-10-2018 IPR036165 YefM-like superfamily CLOST_1785 fa50696f53ceea6b4acae89e83757a99 424 Gene3D G3DSA:1.20.1250.20 224 423 1.3E-15 T 13-10-2018 CLOST_1785 fa50696f53ceea6b4acae89e83757a99 424 SUPERFAMILY SSF103473 23 419 4.58E-51 T 13-10-2018 IPR036259 MFS transporter superfamily CLOST_1785 fa50696f53ceea6b4acae89e83757a99 424 Gene3D G3DSA:1.20.1250.20 22 213 3.0E-30 T 13-10-2018 CLOST_1785 fa50696f53ceea6b4acae89e83757a99 424 Pfam PF07690 Major Facilitator Superfamily 34 380 1.2E-37 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CLOST_1180 f8366db9e41b938f63e4daa64c146ace 300 SUPERFAMILY SSF69318 193 268 2.88E-5 T 13-10-2018 CLOST_1559 02a0099cd9f44a5f13ceb340a67d45de 259 Pfam PF08346 AntA/AntB antirepressor 23 94 1.8E-22 T 13-10-2018 IPR013557 AntA/AntB antirepressor CLOST_2360 e8e5ef33224dc5b996052bd00189bc05 100 Pfam PF10135 Rod binding protein 45 93 4.4E-11 T 13-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal CLOST_1481 2e30df3a2398bad0125410c471898a19 203 Pfam PF02163 Peptidase family M50 118 175 1.6E-7 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 CLOST_0759 374c146b0331002bb7bb6e99f153dd4f 336 Pfam PF06089 L-asparaginase II 7 328 1.7E-109 T 13-10-2018 IPR010349 L-asparaginase II CLOST_0449 efcd5222586ed0173f3e45fd0854e290 133 Pfam PF04138 GtrA-like protein 17 128 1.2E-23 T 13-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 CLOST_0271 fcab3cb548540cc74f2853ceaaa2ff4d 121 Pfam PF06305 Lipopolysaccharide assembly protein A domain 21 83 7.2E-16 T 13-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CLOST_2276 49dd4a677a3ef1538f15de4451afd050 40 Gene3D G3DSA:3.40.30.10 1 40 2.9E-6 T 13-10-2018 CLOST_2276 49dd4a677a3ef1538f15de4451afd050 40 Pfam PF13192 Thioredoxin domain 5 38 1.4E-5 T 13-10-2018 IPR012336 Thioredoxin-like fold CLOST_1218 a6ebfca27cbfa69e2c5e9c43dc866aaa 418 Pfam PF12838 4Fe-4S dicluster domain 290 336 7.3E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CLOST_1218 a6ebfca27cbfa69e2c5e9c43dc866aaa 418 SUPERFAMILY SSF54862 282 356 7.81E-19 T 13-10-2018 CLOST_1218 a6ebfca27cbfa69e2c5e9c43dc866aaa 418 Gene3D G3DSA:3.30.70.20 284 377 4.7E-14 T 13-10-2018 CLOST_1734 f96c0c663c0cfa3b1bd10d5b2f31cb19 128 Pfam PF03963 Flagellar hook capping protein - N-terminal region 9 78 2.4E-23 T 13-10-2018 IPR005648 Flagellar hook capping protein CLOST_1892 6d9acdbf1e68167d84c4f16d5abaabab 239 Gene3D G3DSA:3.30.70.1880 92 239 1.9E-31 T 13-10-2018 CLOST_1892 6d9acdbf1e68167d84c4f16d5abaabab 239 Pfam PF05949 Bacterial protein of unknown function (DUF881) 96 236 4.6E-37 T 13-10-2018 IPR010273 Protein of unknown function DUF881 CLOST_0235 c38b3e3ecf68bec42f51ce5dc60f3300 323 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 77 236 7.0E-37 T 13-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CLOST_0235 c38b3e3ecf68bec42f51ce5dc60f3300 323 Gene3D G3DSA:1.10.260.150 45 322 2.0E-66 T 13-10-2018 CLOST_0235 c38b3e3ecf68bec42f51ce5dc60f3300 323 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 77 237 7.5E-38 T 13-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CLOST_0350 b9d4473b0d67afa40f0391a751ac8e0a 473 Pfam PF00395 S-layer homology domain 405 448 2.7E-8 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0350 b9d4473b0d67afa40f0391a751ac8e0a 473 Pfam PF00395 S-layer homology domain 341 383 2.5E-8 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0350 b9d4473b0d67afa40f0391a751ac8e0a 473 Pfam PF00395 S-layer homology domain 274 313 2.3E-7 T 13-10-2018 IPR001119 S-layer homology domain CLOST_2494 70057bd5777762ef61cc46b60c71a065 120 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 6 115 9.2E-53 T 13-10-2018 IPR014580 Uncharacterised conserved protein UCP033199 CLOST_2494 70057bd5777762ef61cc46b60c71a065 120 PIRSF PIRSF033199 1 116 3.4E-55 T 13-10-2018 IPR014580 Uncharacterised conserved protein UCP033199 CLOST_2494 70057bd5777762ef61cc46b60c71a065 120 Gene3D G3DSA:1.10.8.290 1 120 5.0E-54 T 13-10-2018 IPR023204 SP1917 domain superfamily CLOST_2203 7ce937b4355eacee5700cc4dab14da26 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 276 4.6E-38 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_1570 65e4bfc464444f06a7d3156c8a2fab55 116 SUPERFAMILY SSF52980 11 108 2.04E-24 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CLOST_1570 65e4bfc464444f06a7d3156c8a2fab55 116 Gene3D G3DSA:3.40.1350.10 12 116 6.0E-27 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 CLOST_1570 65e4bfc464444f06a7d3156c8a2fab55 116 Hamap MF_00048 UPF0102 protein YraN [yraN]. 5 115 19.746 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 CLOST_1570 65e4bfc464444f06a7d3156c8a2fab55 116 Pfam PF02021 Uncharacterised protein family UPF0102 12 102 6.0E-25 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 CLOST_0034 73f1f614290e565189614dd64ab67878 509 Pfam PF14262 Carbohydrate-binding domain-containing protein Cthe_2159 78 401 1.6E-58 T 13-10-2018 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 CLOST_1004 828beb9a939c1169f6da85b4b6f0ed0d 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 67 313 3.7E-19 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_2443 1ae148a12db4186bd412cf2af6114c64 121 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 2 112 3.2E-38 T 13-10-2018 IPR018745 Domain of unknown function DUF2294 CLOST_0818 525375a3657ff17f61512e147b7b3be6 87 Pfam PF01695 IstB-like ATP binding protein 1 67 9.1E-21 T 13-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CLOST_0818 525375a3657ff17f61512e147b7b3be6 87 Gene3D G3DSA:3.40.50.300 1 83 2.5E-19 T 13-10-2018 CLOST_1178 ecab5a1917fb025ce941b498b32de5c9 303 SUPERFAMILY SSF53098 22 195 9.32E-27 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_1178 ecab5a1917fb025ce941b498b32de5c9 303 Pfam PF13482 RNase_H superfamily 22 191 1.8E-37 T 13-10-2018 IPR038720 YprB, ribonuclease H-like domain CLOST_1178 ecab5a1917fb025ce941b498b32de5c9 303 Gene3D G3DSA:3.30.420.10 19 220 2.8E-12 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CLOST_1894 7542a66b804512d1d0994780be83a366 243 Pfam PF03799 Cell division protein FtsQ 106 233 6.3E-11 T 13-10-2018 IPR005548 Cell division protein FtsQ/DivIB CLOST_1894 7542a66b804512d1d0994780be83a366 243 Pfam PF08478 POTRA domain, FtsQ-type 39 98 2.2E-11 T 13-10-2018 IPR013685 POTRA domain, FtsQ-type CLOST_0478 a5798dde8d93d7ceeb87c3885c919510 528 PIRSF PIRSF038958 1 522 8.3E-153 T 13-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CLOST_0478 a5798dde8d93d7ceeb87c3885c919510 528 Pfam PF01943 Polysaccharide biosynthesis protein 6 308 1.4E-33 T 13-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CLOST_0478 a5798dde8d93d7ceeb87c3885c919510 528 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 362 504 1.4E-28 T 13-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CLOST_1752 8208862868352787bc16232e87b4ce32 241 Pfam PF02591 C4-type zinc ribbon domain 197 229 1.2E-6 T 13-10-2018 IPR003743 C4-type zinc ribbon domain CLOST_1867 1d8f7efb089a88269cc8208b75e01d47 281 SUPERFAMILY SSF46785 6 73 1.05E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CLOST_1867 1d8f7efb089a88269cc8208b75e01d47 281 SUPERFAMILY SSF53850 84 278 4.81E-20 T 13-10-2018 CLOST_1867 1d8f7efb089a88269cc8208b75e01d47 281 Gene3D G3DSA:1.10.10.10 1 69 2.0E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CLOST_1867 1d8f7efb089a88269cc8208b75e01d47 281 Gene3D G3DSA:3.40.190.290 89 281 4.9E-23 T 13-10-2018 CLOST_1867 1d8f7efb089a88269cc8208b75e01d47 281 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 8.8E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CLOST_1867 1d8f7efb089a88269cc8208b75e01d47 281 Pfam PF03466 LysR substrate binding domain 87 275 4.8E-21 T 13-10-2018 IPR005119 LysR, substrate-binding CLOST_0544 b8c796aed6f690ab80bdb08fd44cbfb3 391 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 380 5.6E-34 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_0718 c9cd47e8140ca6d5265b881ee72f938c 63 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 3.5E-30 T 13-10-2018 IPR019240 Protein of unknown function DUF2196 CLOST_0718 c9cd47e8140ca6d5265b881ee72f938c 63 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 62 1.3E-32 T 13-10-2018 IPR019240 Protein of unknown function DUF2196 CLOST_0111 80ee1e7576480b4f10303adfce8a3d5b 280 Pfam PF12686 Protein of unknown function (DUF3800) 21 265 1.4E-21 T 13-10-2018 IPR024524 Protein of unknown function DUF3800 CLOST_0306 409079e3b43d2e6ba71f98dc80071608 469 Pfam PF03432 Relaxase/Mobilisation nuclease domain 10 248 2.3E-41 T 13-10-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CLOST_0321 ae07276dab399a0ff6a88554d47118ba 631 Pfam PF09972 Predicted membrane protein (DUF2207) 39 550 1.1E-110 T 13-10-2018 IPR018702 Protein of unknown function DUF2207, membrane CLOST_2362 953cf82b5e012cdfa5b31d7bf5e31d30 372 SUPERFAMILY SSF117143 202 330 5.75E-18 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like CLOST_2362 953cf82b5e012cdfa5b31d7bf5e31d30 372 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 296 367 1.2E-16 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CLOST_2362 953cf82b5e012cdfa5b31d7bf5e31d30 372 Pfam PF00460 Flagella basal body rod protein 5 35 3.7E-7 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CLOST_1068 25a3d5dcfdebd6b57f6f99eafa72d69c 280 Pfam PF05681 Fumarate hydratase (Fumerase) 12 278 3.1E-115 T 13-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CLOST_1068 25a3d5dcfdebd6b57f6f99eafa72d69c 280 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 10 278 2.3E-95 T 13-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CLOST_2244 072d145a352540132d214b724bdc07fb 338 Pfam PF04245 37-kD nucleoid-associated bacterial protein 13 333 1.5E-39 T 13-10-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 CLOST_1175 404b4ad53a13168446c10147968b774b 138 Pfam PF12953 Domain of unknown function (DUF3842) 3 130 3.1E-47 T 13-10-2018 IPR024208 Protein of unknown function DUF3842 CLOST_0826 16e2cecaa685e1d64ea6a8d4fbeedcde 109 SUPERFAMILY SSF54285 16 84 9.16E-8 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CLOST_1384 b9e0d684a7a0ac5b777d2876e2a2f563 273 Gene3D G3DSA:3.20.20.70 1 273 5.4E-112 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1384 b9e0d684a7a0ac5b777d2876e2a2f563 273 Pfam PF05853 beta-keto acid cleavage enzyme 3 270 1.6E-104 T 13-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 CLOST_2339 46e1d1157fd343486d24483c91a23076 254 Gene3D G3DSA:3.20.20.370 39 229 2.0E-7 T 13-10-2018 CLOST_2339 46e1d1157fd343486d24483c91a23076 254 SUPERFAMILY SSF88713 35 199 2.19E-8 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CLOST_0046 1ffc81aca92df7b7fbfdf513a0e8992f 388 Pfam PF07907 YibE/F-like protein 135 372 9.1E-71 T 13-10-2018 IPR012507 YibE/F-like CLOST_0379 61a7918c6e1f3f3c3a091d0786f090c3 137 Pfam PF02653 Branched-chain amino acid transport system / permease component 1 123 4.2E-20 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_0355 d1e9c140b18dd7730b55d2f429b99eb9 642 Pfam PF04932 O-Antigen ligase 263 571 2.6E-20 T 13-10-2018 IPR007016 O-antigen ligase-related CLOST_0072 40127e50a34baaf9ca0bd576f3c5e73c 272 Pfam PF02596 Uncharacterised ArCR, COG2043 12 217 5.9E-42 T 13-10-2018 IPR003748 Protein of unknown function DUF169 CLOST_0066 5329ae0364a68b10bb5fc4aee33c2e88 87 Pfam PF01695 IstB-like ATP binding protein 1 67 7.1E-21 T 13-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CLOST_0066 5329ae0364a68b10bb5fc4aee33c2e88 87 Gene3D G3DSA:3.40.50.300 1 83 3.0E-19 T 13-10-2018 CLOST_0687 648370a7feeadfaf5222a9f4a430f7e6 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 48 322 6.6E-38 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_1336 eb92d2f7c1dd56e61aabf2bd7d0d4db5 267 Pfam PF00953 Glycosyl transferase family 4 71 220 2.2E-5 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CLOST_1599 646d103bbfd150503259ab416c0769e2 211 Pfam PF16316 Domain of unknown function (DUF4956) 19 124 1.3E-14 T 13-10-2018 IPR032531 Protein of unknown function DUF4956 CLOST_1530 1231484d90b14dbad95dc14e5c96e609 699 Pfam PF04233 Phage Mu protein F like protein 584 685 9.1E-6 T 13-10-2018 IPR006528 Phage head morphogenesis domain CLOST_0394 2f7759fb49c24c956a1c9fe11e878774 250 Pfam PF06161 Protein of unknown function (DUF975) 86 245 4.6E-24 T 13-10-2018 IPR010380 Protein of unknown function DUF975 CLOST_2472 8153ab6cf42e59b12489fd4e377520c4 306 SUPERFAMILY SSF52540 4 222 1.51E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2472 8153ab6cf42e59b12489fd4e377520c4 306 SMART SM00382 29 214 1.8E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain CLOST_2472 8153ab6cf42e59b12489fd4e377520c4 306 Gene3D G3DSA:3.40.50.300 1 242 2.0E-53 T 13-10-2018 CLOST_2472 8153ab6cf42e59b12489fd4e377520c4 306 Pfam PF00005 ABC transporter 21 162 2.2E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CLOST_2472 8153ab6cf42e59b12489fd4e377520c4 306 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CLOST_1518 2c371c7a5ce9dffdfb6ed3e31a20add8 723 Pfam PF10145 Phage-related minor tail protein 126 315 1.3E-25 T 13-10-2018 IPR010090 Phage tail tape measure protein CLOST_0190 1538b8649b6d5db45fd5066a93a6d12f 694 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 24 2.9E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site CLOST_0190 1538b8649b6d5db45fd5066a93a6d12f 694 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site CLOST_1626 d4f72475a7f67c62be6ffc731301d09a 129 SUPERFAMILY SSF54593 1 128 4.3E-27 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOST_1626 d4f72475a7f67c62be6ffc731301d09a 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 127 2.6E-12 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CLOST_1626 d4f72475a7f67c62be6ffc731301d09a 129 Gene3D G3DSA:3.10.180.10 1 129 1.4E-34 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CLOST_0518 aaa2b90246143f871452b17e7621c207 1231 Pfam PF00395 S-layer homology domain 1173 1215 3.0E-8 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0518 aaa2b90246143f871452b17e7621c207 1231 Pfam PF00395 S-layer homology domain 1108 1150 1.9E-11 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0518 aaa2b90246143f871452b17e7621c207 1231 Pfam PF00395 S-layer homology domain 1048 1086 1.1E-9 T 13-10-2018 IPR001119 S-layer homology domain CLOST_0518 aaa2b90246143f871452b17e7621c207 1231 Gene3D G3DSA:2.160.20.20 470 651 1.7E-5 T 13-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily CLOST_1908 80525247fdc482eac625349492c26cdb 63 SMART SM00530 1 55 4.5E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1908 80525247fdc482eac625349492c26cdb 63 Pfam PF01381 Helix-turn-helix 2 55 1.0E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CLOST_1908 80525247fdc482eac625349492c26cdb 63 Gene3D G3DSA:1.10.260.40 1 60 4.5E-21 T 13-10-2018 CLOST_1908 80525247fdc482eac625349492c26cdb 63 SUPERFAMILY SSF47413 2 61 3.1E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CLOST_1233 8769ee0cac83eb8841f72012967bcaad 427 Pfam PF06838 Methionine gamma-lyase 21 421 4.2E-176 T 13-10-2018 IPR009651 Putative methionine gamma-lyase CLOST_1233 8769ee0cac83eb8841f72012967bcaad 427 Gene3D G3DSA:3.40.640.10 65 279 2.6E-171 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CLOST_1233 8769ee0cac83eb8841f72012967bcaad 427 Gene3D G3DSA:3.90.1150.60 27 418 2.6E-171 T 13-10-2018 CLOST_1233 8769ee0cac83eb8841f72012967bcaad 427 SUPERFAMILY SSF53383 47 376 5.32E-39 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CLOST_0858 26cca4ebf53d1bddea7c1db88c44e26d 170 Pfam PF16152 Domain of unknown function (DUF4860) 53 149 9.7E-24 T 13-10-2018 IPR032340 Protein of unknown function DUF4860 CLOST_1025 d4342a04ad056d02562fd2ebfcfc6433 296 SUPERFAMILY SSF51556 10 280 6.81E-35 T 13-10-2018 IPR032466 Metal-dependent hydrolase CLOST_1025 d4342a04ad056d02562fd2ebfcfc6433 296 Pfam PF01979 Amidohydrolase family 129 268 1.8E-10 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CLOST_1025 d4342a04ad056d02562fd2ebfcfc6433 296 Gene3D G3DSA:3.20.20.140 13 284 2.5E-36 T 13-10-2018 CLOST_0531 910e67fb7aeac48e4af09793a94226ef 260 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 9 258 2.9E-63 T 13-10-2018 IPR005226 UPF0014 family CLOST_0531 910e67fb7aeac48e4af09793a94226ef 260 Pfam PF03649 Uncharacterised protein family (UPF0014) 10 252 4.9E-88 T 13-10-2018 IPR005226 UPF0014 family CLOST_1986 0ebba212f3a27d66c48b3c8a8d53aaa0 244 Pfam PF05857 TraX protein 1 240 1.7E-31 T 13-10-2018 IPR008875 TraX CLOST_0707 73fe234d256e78c4f9dc1849bc83a2dc 429 Pfam PF10011 Predicted membrane protein (DUF2254) 10 380 2.3E-101 T 13-10-2018 IPR018723 Protein of unknown function DUF2254, membrane CLOST_1158 6cbac8b560d7b116fc6c8e9367e278fb 251 SUPERFAMILY SSF52518 16 247 5.61E-55 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold CLOST_1158 6cbac8b560d7b116fc6c8e9367e278fb 251 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 208 7.0E-23 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CLOST_1158 6cbac8b560d7b116fc6c8e9367e278fb 251 Gene3D G3DSA:3.40.50.970 68 250 2.1E-26 T 13-10-2018 CLOST_0786 0cf72c5b17e437a5fc859746f2c4d0f9 403 Pfam PF02687 FtsX-like permease family 297 393 1.8E-13 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CLOST_0181 5bf43706145c7a1c0aa68e1cb60b5952 476 Pfam PF03606 C4-dicarboxylate anaerobic carrier 10 470 3.2E-141 T 13-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CLOST_1551 586b72f0666992a3a25cf99319b79d73 296 Pfam PF03837 RecT family 64 243 3.7E-39 T 13-10-2018 IPR018330 RecT family GO:0003677|GO:0006259 CLOST_0489 fe95bb7593e9421e89d08eb33af585d4 225 SUPERFAMILY SSF52540 3 175 1.1E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_0489 fe95bb7593e9421e89d08eb33af585d4 225 Gene3D G3DSA:3.40.50.300 4 213 1.0E-6 T 13-10-2018 CLOST_0806 d0ae1683119aadb5ded0765f68e88b4f 685 Pfam PF09826 Beta propeller domain 156 677 8.8E-165 T 13-10-2018 IPR019198 Beta propeller domain-containing family CLOST_1278 8a94527f73ef069bbd54c1e83cab4240 304 Pfam PF13280 WYL domain 149 304 7.3E-19 T 13-10-2018 IPR026881 WYL domain CLOST_1278 8a94527f73ef069bbd54c1e83cab4240 304 Pfam PF08279 HTH domain 11 73 1.5E-4 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 CLOST_1708 2729c1f60d3ca72a91edbf5dee4ab546 470 Pfam PF03961 Flagellar Assembly Protein A 17 465 1.5E-110 T 13-10-2018 IPR005646 Flagellar assembly protein A CLOST_0809 c4c16840aab46d76d159aab6bdf55f20 53 Gene3D G3DSA:3.40.50.1390 1 53 1.1E-13 T 13-10-2018 CLOST_0809 c4c16840aab46d76d159aab6bdf55f20 53 SUPERFAMILY SSF53041 1 52 9.81E-7 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 CLOST_0809 c4c16840aab46d76d159aab6bdf55f20 53 Pfam PF00239 Resolvase, N terminal domain 1 51 2.9E-5 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CLOST_1731 79478b13a1bbfdd5c192f58968fe3fe7 260 Pfam PF01618 MotA/TolQ/ExbB proton channel family 101 218 4.0E-26 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel CLOST_1731 79478b13a1bbfdd5c192f58968fe3fe7 260 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 184 201 - T 13-10-2018 IPR000540 Flagellar motor protein MotA, conserved site CLOST_1614 ca9a7cfb3882c0b5a7816091f884fe42 143 Pfam PF07670 Nucleoside recognition 20 110 5.0E-6 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CLOST_1815 1e11a37ab11e429e5b1e7a081eec6afe 336 SUPERFAMILY SSF51412 4 328 1.3E-49 T 13-10-2018 CLOST_1815 1e11a37ab11e429e5b1e7a081eec6afe 336 Gene3D G3DSA:3.20.20.70 1 335 1.7E-70 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CLOST_1815 1e11a37ab11e429e5b1e7a081eec6afe 336 Pfam PF03060 Nitronate monooxygenase 1 331 2.8E-53 T 13-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CLOST_2553 e32d1327c9851720bd6ae970bdf6630b 237 Pfam PF09648 YycH protein 15 234 8.3E-21 T 13-10-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CLOST_0222 d7c424e3dc1fe4c28a565d17616d6778 282 Gene3D G3DSA:3.10.310.50 36 180 3.2E-41 T 13-10-2018 CLOST_0222 d7c424e3dc1fe4c28a565d17616d6778 282 Pfam PF04536 TPM domain 52 171 5.9E-32 T 13-10-2018 IPR007621 TPM domain CLOST_0859 96f1abc35ac86d73ff4f064beabc80e3 165 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 1.8E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site CLOST_0859 96f1abc35ac86d73ff4f064beabc80e3 165 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 24 2.3E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site CLOST_1610 98090ea18dc80b586deaabe756492217 340 Pfam PF12679 ABC-2 family transporter protein 66 268 3.1E-7 T 13-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 CLOST_2541 c7f1e090bae80845194fb975a5dcaa52 148 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 137 3.5E-22 T 13-10-2018 IPR006750 Putative inner membrane exporter, YdcZ CLOST_1947 a9b0b1364327137ad09dc0702dc8ccdf 173 Pfam PF04024 PspC domain 4 58 4.0E-24 T 13-10-2018 IPR007168 Phage shock protein, PspC, N-terminal CLOST_1045 58366dd3c7e4f5f45e1d3881dd5dd039 176 Pfam PF16107 Domain of unknown function (DUF4825) 44 134 1.8E-26 T 13-10-2018 IPR032250 Domain of unknown function DUF4825 CLOST_0816 3a527c0a98ac173e91157741fc6d9e7d 525 SUPERFAMILY SSF53098 174 314 4.17E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily CLOST_0816 3a527c0a98ac173e91157741fc6d9e7d 525 Pfam PF00665 Integrase core domain 151 275 1.9E-10 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 CLOST_2037 ba09ac0c66a0dc37c82fb87c4c8af4b9 368 Pfam PF04294 VanW like protein 195 322 3.3E-52 T 13-10-2018 IPR007391 Vancomycin resistance VanW CLOST_0807 1ce97888d67cd9c90bb4c5360e8c34b4 58 Pfam PF04326 Putative DNA-binding domain 18 57 8.9E-9 T 13-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 CLOST_0807 1ce97888d67cd9c90bb4c5360e8c34b4 58 Gene3D G3DSA:3.30.950.30 1 58 9.4E-10 T 13-10-2018 IPR038461 Schlafen, AAA domain superfamily CLOST_1032 d4753ea10ebee19fc684e1267cbe0df5 193 Pfam PF08747 Domain of unknown function (DUF1788) 66 191 2.8E-45 T 13-10-2018 IPR014858 Protein of unknown function DUF1788 CLOST_1441 972bc9355ee2366eb95fd34cc0f46fcb 378 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 367 2.5E-91 T 13-10-2018 IPR039480 C-C bond lyase-like CLOST_1163 81cf0b2dba1416a41eb54363324d5883 218 Pfam PF04961 Formiminotransferase-cyclodeaminase 18 197 6.5E-64 T 13-10-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CLOST_1163 81cf0b2dba1416a41eb54363324d5883 218 SUPERFAMILY SSF101262 13 217 4.45E-55 T 13-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CLOST_1163 81cf0b2dba1416a41eb54363324d5883 218 Gene3D G3DSA:1.20.120.680 17 217 8.7E-62 T 13-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 CLOST_1981 1563abde0b6250083f737d760a5e2f89 389 Pfam PF01594 AI-2E family transporter 85 372 3.7E-51 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like CLOST_0319 55b7c5690eeb5f703f036c5cb2311cee 342 Pfam PF13240 zinc-ribbon domain 6 28 2.2E-6 T 13-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CLOST_2202 515a8531cc0b6c6d8debba129c3218db 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 258 1.1E-37 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_0819 458b2453cb7a5d34699b285bf561d8cf 791 SUPERFAMILY SSF52540 36 385 4.09E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CLOST_2256 3276748413de67b00d0a146548dac9f4 148 Pfam PF06949 Protein of unknown function (DUF1292) 72 136 1.1E-14 T 13-10-2018 IPR009711 Uncharacterised protein family UPF0473 CLOST_1197 d60206aaa7e75f9314fb2d8be0ebb350 153 Pfam PF12663 Protein of unknown function (DUF3788) 14 150 4.1E-33 T 13-10-2018 IPR024265 Protein of unknown function DUF3788 CLOST_2152 1ede8398d2bf24619dfd13fe999421a8 193 Pfam PF12952 Domain of unknown function (DUF3841) 10 190 2.2E-59 T 13-10-2018 IPR024211 Protein of unknown function DUF3841 CLOST_0088 45e21664684663a04bc1bf49fb661bee 273 Pfam PF02596 Uncharacterised ArCR, COG2043 13 214 3.7E-41 T 13-10-2018 IPR003748 Protein of unknown function DUF169 CLOST_0421 85b5e07ef6eee68bfb9eeb6153f86b30 367 Pfam PF12698 ABC-2 family transporter protein 18 354 3.4E-22 T 13-10-2018 CLOST_1297 06ef2bf4606defde6c5c45d1e1b3dc1a 259 Pfam PF06738 Putative threonine/serine exporter 14 251 3.0E-73 T 13-10-2018 IPR010619 Putative threonine/serine exporter CLOST_1437 8b6eaa5998c2a1ce3c3d1b9a89d2fc84 177 Pfam PF04143 Sulphur transport 6 167 3.3E-37 T 13-10-2018 IPR007272 Sulphur transport domain CLOST_0353 87428fb54111e747909f093f6b91b7ad 251 Pfam PF07833 Copper amine oxidase N-terminal domain 55 138 5.1E-7 T 13-10-2018 IPR012854 Copper amine oxidase-like, N-terminal CLOST_1511 c353a2a81a6f64a68e8565c631a0d50f 189 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 13 150 9.0E-14 T 13-10-2018 IPR018755 Bacteriophage Mu-like, Gp48 CLOST_1728 93bb2d7cf88a8d3a2ff12f5e1006900c 141 Pfam PF03748 Flagellar basal body-associated protein FliL 48 141 6.5E-16 T 13-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CLOST_1549 718c8812da3be124e5bbda27d1940b0b 302 Pfam PF14297 Domain of unknown function (DUF4373) 11 101 2.2E-26 T 13-10-2018 IPR025400 Domain of unknown function DUF4373 CLOST_0729 4568c5fb7611647da830ae3d9809d04c 309 Pfam PF14257 Domain of unknown function (DUF4349) 21 286 1.2E-63 T 13-10-2018 IPR025645 Domain of unknown function DUF4349 CLOST_1536 3786a5eeab8813bec850fbd01deb87cd 153 Pfam PF06356 Protein of unknown function (DUF1064) 44 149 6.3E-30 T 13-10-2018 IPR009414 Protein of unknown function DUF1064 CLOST_1121 4f6b8aed99587aa12d074252fc935b91 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 288 5.3E-40 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_1417 3641877d480f02911ec60818f95c09ba 306 Pfam PF01040 UbiA prenyltransferase family 23 265 5.9E-23 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CLOST_2515 746281ad06d0c1a3c36a717d69d6f3d8 403 Pfam PF13020 Domain of unknown function (DUF3883) 279 375 1.6E-14 T 13-10-2018 IPR024975 Domain of unknown function DUF3883 CLOST_1896 2d3d94a494460c12abaafd9c0a37f02e 368 Pfam PF01098 Cell cycle protein 16 367 6.4E-108 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_1896 2d3d94a494460c12abaafd9c0a37f02e 368 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 13 366 1.4E-113 T 13-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CLOST_0546 e9ffa9d9c8ae6fed50d5bd0a4a15d722 231 Pfam PF04474 Protein of unknown function (DUF554) 2 220 9.7E-81 T 13-10-2018 IPR007563 Protein of unknown function DUF554 CLOST_1126 1a4cc2d24d6f244c30cdc608d55082fd 201 Pfam PF04286 Protein of unknown function (DUF445) 11 132 4.1E-19 T 13-10-2018 IPR007383 Protein of unknown function DUF445 CLOST_1126 1a4cc2d24d6f244c30cdc608d55082fd 201 Pfam PF04286 Protein of unknown function (DUF445) 110 198 1.2E-15 T 13-10-2018 IPR007383 Protein of unknown function DUF445 CLOST_1196 e11b76bc13067f8db004257786abd103 298 Gene3D G3DSA:3.40.1350.10 19 115 6.9E-6 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 CLOST_2573 4d96f47f49900df66f8cdfb365647e84 82 Pfam PF11823 Protein of unknown function (DUF3343) 2 68 1.8E-23 T 13-10-2018 IPR021778 Domain of unknown function DUF3343 CLOST_1174 7f22445c1de79da500247a2c69de1d20 62 Pfam PF10133 Predicted RNA-binding protein 1 60 2.1E-24 T 13-10-2018 IPR019300 RNA-binding protein, predicted CLOST_0851 376987eb3e561f29242c407ab8521ba1 393 Pfam PF01882 Protein of unknown function DUF58 193 271 4.3E-14 T 13-10-2018 IPR002881 Domain of unknown function DUF58 CLOST_1198 d8e3c3c219e1f5078081d2348ea8b07c 288 Pfam PF06207 Protein of unknown function (DUF1002) 37 254 9.2E-77 T 13-10-2018 IPR009343 Protein of unknown function DUF1002 CLOST_1335 3925fe5c50134d747e57e326cad3854d 372 Pfam PF12982 Protein of unknown function (DUF3866) 34 352 1.3E-122 T 13-10-2018 IPR024479 Protein of unknown function DUF3866 CLOST_0592 5f6052a7aa39a60938a261fff6740358 175 Pfam PF02417 Chromate transporter 3 167 1.1E-43 T 13-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CLOST_0378 1c4fcf842cfcc2a4c86502b3d8ce8602 180 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 168 3.2E-19 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_0668 52563c9f11e2373248b7b5db276ab668 134 Pfam PF09945 Predicted membrane protein (DUF2177) 4 125 9.4E-45 T 13-10-2018 IPR018687 Protein of unknown function DUF2177, membrane CLOST_2530 482daece0012eb7520cd24e0b71163ea 582 Pfam PF03235 Protein of unknown function DUF262 8 214 4.1E-34 T 13-10-2018 IPR004919 Domain of unknown function DUF262 CLOST_2530 482daece0012eb7520cd24e0b71163ea 582 Pfam PF07510 Protein of unknown function (DUF1524) 413 570 1.1E-19 T 13-10-2018 IPR011089 Domain of unknown function DUF1524 CLOST_1480 4ace2058b88a22205133e2d5cd458723 232 Pfam PF02616 Segregation and condensation protein ScpA 20 225 2.9E-18 T 13-10-2018 IPR003768 Segregation and condensation protein A CLOST_0639 8e4b075ee3b252fe36b26cdb267120c1 56 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 7 51 1.2E-14 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 CLOST_1120 a06307b33d158015298b920b751097b1 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 332 3.1E-44 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CLOST_1476 a2d8018f7ab03acd9df5720d67b6cf7c 139 SUPERFAMILY SSF55729 25 109 4.51E-5 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase CLOST_2503 a4ccd5dd245e90b4096d9003ff6bee8c 115 Pfam PF05656 Protein of unknown function (DUF805) 7 109 3.3E-24 T 13-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 CLOST_2357 1d0537f93a977817da26901502aa5f61 664 Pfam PF09992 Phosphodiester glycosidase 202 367 2.5E-29 T 13-10-2018 IPR018711 Phosphodiester glycosidase CLOST_0446 72eddcc8535b77a0081d2aa7db1ae332 499 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 133 269 1.5E-6 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like CLOST_0964 828d3eaaca85109edf7e0ede6e4bd033 504 Pfam PF03606 C4-dicarboxylate anaerobic carrier 12 501 5.2E-130 T 13-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021