locus-tag	class	description
AAJCM20276_00010	COG0318	PFAM AMP-dependent synthetase and ligase
AAJCM20276_00020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAJCM20276_00030	COG0156	8-amino-7-oxononanoate synthase activity
AAJCM20276_00040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_00160	COG3093	addiction module antidote protein HigA
AAJCM20276_00250	COG0582	viral genome integration into host DNA
AAJCM20276_00260	COG0519	Catalyzes the synthesis of GMP from XMP
AAJCM20276_00260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AAJCM20276_00320	COG0246	Mannitol dehydrogenase
AAJCM20276_00340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAJCM20276_00450	COG1881	PFAM PEBP family protein
AAJCM20276_00470	COG1278	Cold shock
AAJCM20276_00510	COG1271	oxidase subunit
AAJCM20276_00520	COG1294	oxidase, subunit
AAJCM20276_00600	COG1393	Belongs to the ArsC family
AAJCM20276_00610	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_00620	COG4993	Dehydrogenase
AAJCM20276_00660	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AAJCM20276_00670	COG0488	(ABC) transporter
AAJCM20276_00690	COG2091	lysine biosynthetic process via aminoadipic acid
AAJCM20276_00710	COG2814	Major facilitator Superfamily
AAJCM20276_00720	COG1566	PFAM secretion protein HlyD family protein
AAJCM20276_00790	COG0431	NADPH-dependent FMN reductase
AAJCM20276_00810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AAJCM20276_00840	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AAJCM20276_00880	COG0859	PFAM glycosyl transferase family 9
AAJCM20276_00890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AAJCM20276_00900	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_00910	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AAJCM20276_00920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAJCM20276_00930	COG1120	ATPase activity
AAJCM20276_00970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AAJCM20276_00980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AAJCM20276_00990	COG1104	cysteine desulfurase activity
AAJCM20276_01010	COG0482	sulfurtransferase activity
AAJCM20276_01050	COG1505	serine-type exopeptidase activity
AAJCM20276_01060	COG0582	viral genome integration into host DNA
AAJCM20276_01070	COG3311	Transcriptional regulator
AAJCM20276_01080	COG1569	PIN domain
AAJCM20276_01200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAJCM20276_01210	COG0424	maF-like protein
AAJCM20276_01220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AAJCM20276_01230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAJCM20276_01240	COG1981	membrane
AAJCM20276_01310	COG2814	Major facilitator Superfamily
AAJCM20276_01330	COG0436	Aminotransferase
AAJCM20276_01340	COG1914	H( )-stimulated, divalent metal cation uptake system
AAJCM20276_01350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAJCM20276_01370	COG0784	Response regulator, receiver
AAJCM20276_01370	COG2198	Histidine kinase
AAJCM20276_01370	COG5002	protein histidine kinase activity
AAJCM20276_01440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AAJCM20276_01450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AAJCM20276_01510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AAJCM20276_01580	COG3293	Transposase
AAJCM20276_01680	COG0357	Ribosomal RNA small subunit methyltransferase G
AAJCM20276_01690	COG0445	tRNA wobble uridine modification
AAJCM20276_01700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AAJCM20276_01710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AAJCM20276_01760	COG4232	protein-disulfide reductase activity
AAJCM20276_01780	COG1643	Atp-dependent helicase
AAJCM20276_01800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AAJCM20276_01810	COG2205	protein histidine kinase activity
AAJCM20276_01820	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_01840	COG0443	Heat shock 70 kDa protein
AAJCM20276_01850	COG0484	heat shock protein binding
AAJCM20276_01910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAJCM20276_01920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAJCM20276_01960	COG0702	epimerase
AAJCM20276_01970	COG1733	regulation of RNA biosynthetic process
AAJCM20276_01990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AAJCM20276_02000	COG0343	queuine tRNA-ribosyltransferase activity
AAJCM20276_02040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAJCM20276_02050	COG0596	Alpha beta hydrolase
AAJCM20276_02050	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAJCM20276_02060	COG0022	dehydrogenase e1 component
AAJCM20276_02070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AAJCM20276_02100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AAJCM20276_02110	COG0805	protein transport
AAJCM20276_02120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAJCM20276_02190	COG0297	glycogen (starch) synthase activity
AAJCM20276_02260	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AAJCM20276_02270	COG1660	Displays ATPase and GTPase activities
AAJCM20276_02290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AAJCM20276_02300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AAJCM20276_02320	COG0408	coproporphyrinogen oxidase activity
AAJCM20276_02330	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AAJCM20276_02360	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AAJCM20276_02420	COG0402	S-adenosylhomocysteine deaminase activity
AAJCM20276_02440	COG4993	Dehydrogenase
AAJCM20276_02490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAJCM20276_02510	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AAJCM20276_02520	COG1138	Cytochrome C-type biogenesis protein
AAJCM20276_02530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAJCM20276_02540	COG3088	subunit of a heme lyase
AAJCM20276_02560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAJCM20276_02570	COG2813	Specifically methylates the guanine in position
AAJCM20276_02570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAJCM20276_02590	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_02630	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_02660	COG3128	pkhd-type hydroxylase
AAJCM20276_02710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AAJCM20276_02720	COG2070	2-Nitropropane dioxygenase
AAJCM20276_02740	COG0129	dihydroxy-acid dehydratase activity
AAJCM20276_02750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAJCM20276_02770	COG0583	DNA-binding transcription factor activity
AAJCM20276_02780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAJCM20276_02810	COG3293	Transposase
AAJCM20276_02840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAJCM20276_02870	COG1742	UPF0060 membrane protein
AAJCM20276_02880	COG0602	queuosine metabolic process
AAJCM20276_02890	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AAJCM20276_02960	COG0284	orotidine-5'-phosphate decarboxylase activity
AAJCM20276_02970	COG0135	phosphoribosylanthranilate isomerase activity
AAJCM20276_02980	COG0582	viral genome integration into host DNA
AAJCM20276_03020	COG0210	DNA helicase
AAJCM20276_03080	COG0210	DNA helicase
AAJCM20276_03110	COG2072	flavoprotein involved in K transport
AAJCM20276_03120	COG0431	NADPH-dependent FMN reductase
AAJCM20276_03210	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_03230	COG3256	nitric oxide reductase
AAJCM20276_03240	COG3189	MarR family transcriptional regulator
AAJCM20276_03330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAJCM20276_03390	COG5489	Protein of unknown function (DUF736)
AAJCM20276_03400	COG1476	TRANSCRIPTIONal
AAJCM20276_03500	COG0741	lytic transglycosylase activity
AAJCM20276_03570	COG4962	Type ii secretion system protein e
AAJCM20276_03600	COG3451	type IV secretory pathway VirB4
AAJCM20276_03670	COG0583	DNA-binding transcription factor activity
AAJCM20276_03740	COG0625	glutathione transferase activity
AAJCM20276_03780	COG0596	Alpha beta hydrolase
AAJCM20276_03790	COG2226	methyltransferase
AAJCM20276_03940	COG0450	alkyl hydroperoxide reductase
AAJCM20276_03960	COG4988	ABC transporter
AAJCM20276_03970	COG1132	(ABC) transporter
AAJCM20276_03980	COG1271	oxidase subunit
AAJCM20276_03990	COG1294	oxidase, subunit
AAJCM20276_04040	COG3290	protein histidine kinase activity
AAJCM20276_04060	COG1595	DNA-templated transcription, initiation
AAJCM20276_04110	COG2801	Transposase and inactivated derivatives
AAJCM20276_04120	COG3344	reverse transcriptase
AAJCM20276_04130	COG3344	reverse transcriptase
AAJCM20276_04170	COG3547	Transposase (IS116 IS110 IS902 family)
AAJCM20276_04360	COG2271	Major facilitator Superfamily
AAJCM20276_04390	COG0583	DNA-binding transcription factor activity
AAJCM20276_04490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAJCM20276_04510	COG3293	Transposase
AAJCM20276_04620	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AAJCM20276_04640	COG0587	DNA-directed DNA polymerase activity
AAJCM20276_04670	COG0210	DNA helicase
AAJCM20276_04710	COG1201	RNA secondary structure unwinding
AAJCM20276_04760	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AAJCM20276_04950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAJCM20276_05210	COG2963	transposase activity
AAJCM20276_05220	COG3436	PFAM IS66 Orf2 family protein
AAJCM20276_05230	COG4372	Transposase
AAJCM20276_05240	COG4372	Transposase
AAJCM20276_05300	COG0564	pseudouridine synthase activity
AAJCM20276_05320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AAJCM20276_05330	COG0667	Aldo Keto reductase
AAJCM20276_05340	COG1420	regulation of RNA biosynthetic process
AAJCM20276_05400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AAJCM20276_05430	COG0469	pyruvate kinase activity
AAJCM20276_05440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AAJCM20276_05450	COG0351	phosphomethylpyrimidine kinase
AAJCM20276_05450	COG0352	thiamine-phosphate diphosphorylase activity
AAJCM20276_05490	COG0802	atpase or kinase
AAJCM20276_05500	COG2887	Belongs to the helicase family. UvrD subfamily
AAJCM20276_05510	COG1074	ATP-dependent DNA helicase activity
AAJCM20276_05560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AAJCM20276_05570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AAJCM20276_05590	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAJCM20276_05600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAJCM20276_05640	COG2875	Belongs to the precorrin methyltransferase family
AAJCM20276_05670	COG2099	Precorrin-6x reductase
AAJCM20276_05730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AAJCM20276_05800	COG0560	Phosphoserine phosphatase
AAJCM20276_05800	COG3830	Belongs to the UPF0237 family
AAJCM20276_05810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AAJCM20276_05820	COG0028	Belongs to the TPP enzyme family
AAJCM20276_05840	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AAJCM20276_05850	COG3293	Transposase
AAJCM20276_05870	COG2963	transposase activity
AAJCM20276_05880	COG3436	PFAM IS66 Orf2 family protein
AAJCM20276_05900	COG3335	DDE superfamily endonuclease
AAJCM20276_05970	COG3293	Transposase
AAJCM20276_06000	COG0436	Aminotransferase
AAJCM20276_06030	COG0511	ligase activity, forming carbon-carbon bonds
AAJCM20276_06040	COG4221	oxidoreductase activity
AAJCM20276_06050	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AAJCM20276_06060	COG1984	allophanate hydrolase subunit 2
AAJCM20276_06070	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AAJCM20276_06080	COG0697	spore germination
AAJCM20276_06090	COG2271	Major facilitator Superfamily
AAJCM20276_06170	COG0133	tryptophan synthase activity
AAJCM20276_06180	COG0159	tryptophan synthase activity
AAJCM20276_06500	COG2983	Belongs to the UPF0260 family
AAJCM20276_06600	COG0492	ferredoxin-NADP+ reductase activity
AAJCM20276_06610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AAJCM20276_06640	COG0506	proline dehydrogenase activity
AAJCM20276_06640	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AAJCM20276_06640	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AAJCM20276_06650	COG0655	NAD(P)H dehydrogenase (quinone) activity
AAJCM20276_06660	COG0583	DNA-binding transcription factor activity
AAJCM20276_06690	COG0307	riboflavin synthase, alpha
AAJCM20276_06700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AAJCM20276_06700	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AAJCM20276_06710	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AAJCM20276_06730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAJCM20276_06740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AAJCM20276_06860	COG1252	NADH dehydrogenase
AAJCM20276_06870	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_06910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAJCM20276_06910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAJCM20276_06920	COG0509	glycine decarboxylation via glycine cleavage system
AAJCM20276_06930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_06940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AAJCM20276_06950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AAJCM20276_06990	COG0776	regulation of translation
AAJCM20276_07050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AAJCM20276_07090	COG2096	Adenosyltransferase
AAJCM20276_07140	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AAJCM20276_07160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AAJCM20276_07210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAJCM20276_07220	COG1758	RNA polymerase activity
AAJCM20276_07230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAJCM20276_07240	COG0736	holo-[acyl-carrier-protein] synthase activity
AAJCM20276_07250	COG0681	Belongs to the peptidase S26 family
AAJCM20276_07260	COG0571	ribonuclease III activity
AAJCM20276_07270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AAJCM20276_07280	COG0528	UMP kinase activity
AAJCM20276_07290	COG0233	cytoplasmic translational termination
AAJCM20276_07300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AAJCM20276_07310	COG0575	Belongs to the CDS family
AAJCM20276_07320	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AAJCM20276_07330	COG0750	zinc metalloprotease
AAJCM20276_07340	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAJCM20276_07360	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAJCM20276_07370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AAJCM20276_07380	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAJCM20276_07390	COG3494	Protein of unknown function (DUF1009)
AAJCM20276_07430	COG0346	lactoylglutathione lyase activity
AAJCM20276_07450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AAJCM20276_07460	COG0594	ribonuclease P activity
AAJCM20276_07470	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AAJCM20276_07480	COG0706	membrane insertase activity
AAJCM20276_07490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AAJCM20276_07500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AAJCM20276_07530	COG0670	Belongs to the BI1 family
AAJCM20276_07570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AAJCM20276_07610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AAJCM20276_07650	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AAJCM20276_07670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAJCM20276_07710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AAJCM20276_07760	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AAJCM20276_07770	COG1396	sequence-specific DNA binding
AAJCM20276_07790	COG0629	single-stranded DNA binding
AAJCM20276_07800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AAJCM20276_07800	COG2010	Cytochrome c
AAJCM20276_07830	COG0326	Molecular chaperone. Has ATPase activity
AAJCM20276_07850	COG0488	(ABC) transporter
AAJCM20276_07860	COG0784	Response regulator, receiver
AAJCM20276_07900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAJCM20276_07940	COG1271	oxidase subunit
AAJCM20276_07950	COG1294	oxidase, subunit
AAJCM20276_07970	COG0243	molybdopterin cofactor binding
AAJCM20276_07990	COG0315	cyclic pyranopterin monophosphate synthase activity
AAJCM20276_07990	COG0746	molybdenum cofactor guanylyltransferase activity
AAJCM20276_08010	COG0314	molybdopterin synthase activity
AAJCM20276_08020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AAJCM20276_08070	COG3415	Transposase
AAJCM20276_08080	COG3335	DDE superfamily endonuclease
AAJCM20276_08090	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AAJCM20276_08110	COG4786	Flagellar basal body rod
AAJCM20276_08120	COG4786	Flagellar basal body rod
AAJCM20276_08140	COG0778	Nitroreductase
AAJCM20276_08150	COG0477	Major facilitator Superfamily
AAJCM20276_08210	COG1322	Protein conserved in bacteria
AAJCM20276_08220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAJCM20276_08280	COG1877	trehalose-phosphatase activity
AAJCM20276_08290	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AAJCM20276_08340	COG0542	response to heat
AAJCM20276_08380	COG3038	cytochrome b561
AAJCM20276_08410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AAJCM20276_08450	COG2072	flavoprotein involved in K transport
AAJCM20276_08480	COG3293	Transposase
AAJCM20276_08510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAJCM20276_08520	COG1116	anion transmembrane transporter activity
AAJCM20276_08530	COG0864	Transcriptional regulator
AAJCM20276_08550	COG3665	Urea carboxylase-associated protein
AAJCM20276_08590	COG2072	flavoprotein involved in K transport
AAJCM20276_08610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_08630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAJCM20276_08650	COG0583	DNA-binding transcription factor activity
AAJCM20276_08660	COG1126	abc transporter atp-binding protein
AAJCM20276_08760	COG0538	isocitrate dehydrogenase activity
AAJCM20276_08800	COG0328	RNA-DNA hybrid ribonuclease activity
AAJCM20276_08810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AAJCM20276_08820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AAJCM20276_08850	COG0405	Gamma-glutamyltransferase
AAJCM20276_08880	COG0436	Aminotransferase
AAJCM20276_08890	COG0436	Aminotransferase
AAJCM20276_08910	COG3956	TIGRFAM MazG family protein
AAJCM20276_08940	COG1733	regulation of RNA biosynthetic process
AAJCM20276_08960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AAJCM20276_09000	COG2207	Transcriptional regulator
AAJCM20276_09010	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_09020	COG3118	belongs to the thioredoxin family
AAJCM20276_09030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AAJCM20276_09040	COG2835	tetraacyldisaccharide 4'-kinase activity
AAJCM20276_09060	COG1032	radical SAM domain protein
AAJCM20276_09150	COG1596	polysaccharide export
AAJCM20276_09160	COG3750	Belongs to the UPF0335 family
AAJCM20276_09170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AAJCM20276_09200	COG0406	alpha-ribazole phosphatase activity
AAJCM20276_09210	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AAJCM20276_09220	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AAJCM20276_09300	COG4988	ABC transporter
AAJCM20276_09310	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AAJCM20276_09330	COG0514	ATP-dependent DNA helicase (RecQ)
AAJCM20276_09370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AAJCM20276_09390	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_09420	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_09440	COG5002	protein histidine kinase activity
AAJCM20276_09540	COG3293	Transposase
AAJCM20276_09620	COG2175	clavaminate synthase activity
AAJCM20276_09630	COG1113	amino acid transport
AAJCM20276_09650	COG2963	transposase activity
AAJCM20276_09660	COG3436	PFAM IS66 Orf2 family protein
AAJCM20276_09670	COG1116	anion transmembrane transporter activity
AAJCM20276_09680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAJCM20276_09730	COG0583	DNA-binding transcription factor activity
AAJCM20276_09750	COG0583	DNA-binding transcription factor activity
AAJCM20276_09780	COG2132	Multicopper oxidase
AAJCM20276_09790	COG2814	Major facilitator Superfamily
AAJCM20276_09860	COG3293	Transposase
AAJCM20276_09930	COG0740	serine-type endopeptidase activity
AAJCM20276_09960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AAJCM20276_09980	COG1766	The M ring may be actively involved in energy transduction
AAJCM20276_09990	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AAJCM20276_10010	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AAJCM20276_10020	COG2204	response regulator
AAJCM20276_10030	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AAJCM20276_10040	COG2801	Transposase and inactivated derivatives
AAJCM20276_10060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AAJCM20276_10080	COG3293	Transposase
AAJCM20276_10100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AAJCM20276_10110	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AAJCM20276_10120	COG1137	ATPase activity
AAJCM20276_10220	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AAJCM20276_10280	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AAJCM20276_10290	COG1335	isochorismatase
AAJCM20276_10300	COG1744	ABC transporter substrate-binding protein PnrA-like
AAJCM20276_10310	COG3845	ABC transporter
AAJCM20276_10330	COG1079	Belongs to the binding-protein-dependent transport system permease family
AAJCM20276_10350	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAJCM20276_10350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAJCM20276_10360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAJCM20276_10360	COG1372	Participates in initiation and elongation during chromosome replication
AAJCM20276_10380	COG2244	polysaccharide biosynthetic process
AAJCM20276_10390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAJCM20276_10400	COG3335	DDE superfamily endonuclease
AAJCM20276_10430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAJCM20276_10460	COG2351	hydroxyisourate hydrolase activity
AAJCM20276_10490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AAJCM20276_10560	COG0583	DNA-binding transcription factor activity
AAJCM20276_10600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_10610	COG0402	S-adenosylhomocysteine deaminase activity
AAJCM20276_10740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAJCM20276_10760	COG0181	hydroxymethylbilane synthase activity
AAJCM20276_10770	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AAJCM20276_10830	COG0004	ammonium transporteR
AAJCM20276_10880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_10890	COG0840	transmembrane signaling receptor activity
AAJCM20276_10910	COG2198	Histidine kinase
AAJCM20276_10910	COG0643	Histidine kinase
AAJCM20276_10920	COG0835	chemotaxis
AAJCM20276_10930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AAJCM20276_10940	COG2201	protein-glutamate methylesterase activity
AAJCM20276_10950	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_10960	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AAJCM20276_10980	COG0488	(ABC) transporter
AAJCM20276_10990	COG0105	UTP biosynthetic process
AAJCM20276_11030	COG2706	6-phosphogluconolactonase activity
AAJCM20276_11040	COG0281	malic enzyme
AAJCM20276_11060	COG0215	cysteine-tRNA ligase activity
AAJCM20276_11090	COG5492	domain, Protein
AAJCM20276_11090	COG3583	domain protein
AAJCM20276_11090	COG1621	beta-fructofuranosidase activity
AAJCM20276_11140	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAJCM20276_11140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_11160	COG1760	l-serine dehydratase
AAJCM20276_11170	COG4638	Rieske (2fe-2S)
AAJCM20276_11200	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAJCM20276_11200	COG1902	pentaerythritol trinitrate reductase activity
AAJCM20276_11210	COG0247	lactate metabolic process
AAJCM20276_11210	COG2181	nitrate reductase activity
AAJCM20276_11240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AAJCM20276_11250	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AAJCM20276_11300	COG0583	DNA-binding transcription factor activity
AAJCM20276_11360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AAJCM20276_11370	COG3153	acetyltransferase
AAJCM20276_11370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAJCM20276_11400	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_11420	COG0675	Transposase, IS605 OrfB family
AAJCM20276_11440	COG4175	Glycine betaine
AAJCM20276_11520	COG1113	amino acid transport
AAJCM20276_11530	COG3588	fructose-bisphosphate aldolase
AAJCM20276_11540	COG3961	Belongs to the TPP enzyme family
AAJCM20276_11550	COG0247	lactate metabolic process
AAJCM20276_11560	COG1139	Iron-sulfur cluster binding protein
AAJCM20276_11630	COG0052	Belongs to the universal ribosomal protein uS2 family
AAJCM20276_11640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AAJCM20276_11650	COG1381	Involved in DNA repair and RecF pathway recombination
AAJCM20276_11680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAJCM20276_11730	COG3261	NADH dehydrogenase
AAJCM20276_11730	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AAJCM20276_11740	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_11750	COG1183	phosphatidylcholine synthase activity
AAJCM20276_11760	COG0688	phosphatidylethanolamine metabolic process
AAJCM20276_11800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAJCM20276_11850	COG2884	Cell division ATP-binding protein ftsE
AAJCM20276_11890	COG2081	HI0933 family
AAJCM20276_11900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AAJCM20276_11910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AAJCM20276_11930	COG0628	permease
AAJCM20276_11940	COG3293	Transposase
AAJCM20276_11970	COG3293	Transposase
AAJCM20276_12010	COG0463	Glycosyl transferase, family 2
AAJCM20276_12030	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_12130	COG0667	Aldo Keto reductase
AAJCM20276_12160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AAJCM20276_12170	COG0778	Nitroreductase
AAJCM20276_12190	COG5564	TIM-barrel signal transduction protein
AAJCM20276_12200	COG5441	Belongs to the UPF0261 family
AAJCM20276_12220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AAJCM20276_12250	COG2837	iron assimilation
AAJCM20276_12260	COG2814	Major facilitator Superfamily
AAJCM20276_12320	COG0101	tRNA pseudouridine synthase activity
AAJCM20276_12330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AAJCM20276_12340	COG0242	peptide deformylase activity
AAJCM20276_12380	COG3145	DNA-N1-methyladenine dioxygenase activity
AAJCM20276_12420	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AAJCM20276_12490	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AAJCM20276_12520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AAJCM20276_12530	COG0574	Belongs to the PEP-utilizing enzyme family
AAJCM20276_12530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AAJCM20276_12540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AAJCM20276_12550	COG0497	DNA recombination
AAJCM20276_12560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAJCM20276_12590	COG0849	cell division
AAJCM20276_12600	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AAJCM20276_12610	COG1181	Belongs to the D-alanine--D-alanine ligase family
AAJCM20276_12620	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AAJCM20276_12630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AAJCM20276_12640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AAJCM20276_12660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AAJCM20276_12670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAJCM20276_12680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AAJCM20276_12690	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AAJCM20276_12720	COG0275	rRNA processing
AAJCM20276_12730	COG2001	Belongs to the MraZ family
AAJCM20276_12740	COG0657	acetylesterase activity
AAJCM20276_12760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAJCM20276_12770	COG4774	siderophore transport
AAJCM20276_12790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AAJCM20276_12800	COG0110	maltose O-acetyltransferase activity
AAJCM20276_12810	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AAJCM20276_12820	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAJCM20276_12840	COG0047	phosphoribosylformylglycinamidine synthase activity
AAJCM20276_12850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAJCM20276_12860	COG0271	Belongs to the BolA IbaG family
AAJCM20276_12870	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AAJCM20276_12890	COG0792	nuclease activity
AAJCM20276_12910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAJCM20276_12920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AAJCM20276_12930	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AAJCM20276_12940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AAJCM20276_12950	COG3541	Predicted nucleotidyltransferase
AAJCM20276_12970	COG0138	bifunctional purine biosynthesis protein purh
AAJCM20276_12980	COG0439	Biotin carboxylase
AAJCM20276_12990	COG0511	ligase activity, forming carbon-carbon bonds
AAJCM20276_13000	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AAJCM20276_13050	COG1295	ribonuclease BN
AAJCM20276_13070	COG0521	Mo-molybdopterin cofactor biosynthetic process
AAJCM20276_13220	COG2205	protein histidine kinase activity
AAJCM20276_13240	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AAJCM20276_13270	COG0113	porphobilinogen synthase activity
AAJCM20276_13310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAJCM20276_13360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAJCM20276_13370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AAJCM20276_13370	COG2010	Cytochrome c
AAJCM20276_13400	COG0477	Major facilitator Superfamily
AAJCM20276_13440	COG0723	plastoquinol--plastocyanin reductase activity
AAJCM20276_13490	COG0424	maF-like protein
AAJCM20276_13500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AAJCM20276_13510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AAJCM20276_13520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AAJCM20276_13580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AAJCM20276_13590	COG3158	transport of potassium into the cell
AAJCM20276_13600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAJCM20276_13660	COG1054	Belongs to the UPF0176 family
AAJCM20276_13670	COG0667	Aldo Keto reductase
AAJCM20276_13820	COG0552	protein localization to endoplasmic reticulum
AAJCM20276_13830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAJCM20276_13840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AAJCM20276_13870	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_13880	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_13890	COG0431	NADPH-dependent FMN reductase
AAJCM20276_13900	COG5001	Diguanylate cyclase
AAJCM20276_13920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AAJCM20276_13960	COG3293	Transposase
AAJCM20276_13980	COG0481	GTPase activity
AAJCM20276_13990	COG2244	polysaccharide biosynthetic process
AAJCM20276_14000	COG0778	Nitroreductase
AAJCM20276_14010	COG0277	FAD linked oxidase domain protein
AAJCM20276_14030	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AAJCM20276_14050	COG0025	NhaP-type Na H and K H
AAJCM20276_14070	COG0484	heat shock protein binding
AAJCM20276_14090	COG0772	Belongs to the SEDS family
AAJCM20276_14100	COG0768	penicillin binding
AAJCM20276_14160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AAJCM20276_14170	COG0193	aminoacyl-tRNA hydrolase activity
AAJCM20276_14180	COG0012	GTP binding
AAJCM20276_14190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AAJCM20276_14200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AAJCM20276_14210	COG0799	negative regulation of ribosome biogenesis
AAJCM20276_14230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AAJCM20276_14240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AAJCM20276_14250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AAJCM20276_14270	COG0505	Belongs to the CarA family
AAJCM20276_14290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAJCM20276_14320	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_14350	COG0010	Belongs to the arginase family
AAJCM20276_14370	COG1610	YqeY-like protein
AAJCM20276_14380	COG0358	DNA primase activity
AAJCM20276_14390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AAJCM20276_14410	COG0360	Binds together with S18 to 16S ribosomal RNA
AAJCM20276_14420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAJCM20276_14430	COG0359	binds to the 23S rRNA
AAJCM20276_14440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AAJCM20276_14450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAJCM20276_14460	COG0527	aspartate kinase activity
AAJCM20276_14470	COG2070	2-Nitropropane dioxygenase
AAJCM20276_14490	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AAJCM20276_14500	COG0124	histidyl-tRNA synthetase
AAJCM20276_14510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AAJCM20276_14520	COG3706	GGDEF domain
AAJCM20276_14610	COG1530	ribonuclease E activity
AAJCM20276_14620	COG0556	nucleotide-excision repair
AAJCM20276_14640	COG5001	Diguanylate cyclase
AAJCM20276_14640	COG3300	MHYT domain
AAJCM20276_14660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AAJCM20276_14670	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AAJCM20276_14680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AAJCM20276_14730	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_14740	COG3293	Transposase
AAJCM20276_14770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAJCM20276_14790	COG2353	YceI-like domain
AAJCM20276_14800	COG3384	dioxygenase
AAJCM20276_14810	COG0583	DNA-binding transcription factor activity
AAJCM20276_14830	COG3293	Transposase
AAJCM20276_14860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAJCM20276_14870	COG2814	Major facilitator Superfamily
AAJCM20276_14890	COG0259	pyridoxamine-phosphate oxidase activity
AAJCM20276_14900	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AAJCM20276_14910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AAJCM20276_14920	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AAJCM20276_14930	COG0604	alcohol dehydrogenase
AAJCM20276_14960	COG1902	pentaerythritol trinitrate reductase activity
AAJCM20276_14990	COG4974	Belongs to the 'phage' integrase family
AAJCM20276_15010	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_15060	COG0411	ABC transporter
AAJCM20276_15100	COG0583	DNA-binding transcription factor activity
AAJCM20276_15130	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AAJCM20276_15140	COG0830	nickel cation binding
AAJCM20276_15160	COG0804	urea catabolic process
AAJCM20276_15170	COG0832	Belongs to the urease beta subunit family
AAJCM20276_15180	COG0831	urea catabolic process
AAJCM20276_15190	COG0829	nickel cation binding
AAJCM20276_15210	COG0248	Ppx GppA phosphatase
AAJCM20276_15280	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AAJCM20276_15290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AAJCM20276_15300	COG0668	transmembrane transport
AAJCM20276_15320	COG0180	Tryptophanyl-tRNA synthetase
AAJCM20276_15350	COG0545	Peptidyl-prolyl cis-trans isomerase
AAJCM20276_15360	COG0137	argininosuccinate synthase activity
AAJCM20276_15380	COG0024	Methionine aminopeptidase
AAJCM20276_15400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AAJCM20276_15410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AAJCM20276_15420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AAJCM20276_15460	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_15520	COG0564	pseudouridine synthase activity
AAJCM20276_15530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AAJCM20276_15550	COG2814	Major facilitator Superfamily
AAJCM20276_15580	COG4993	Dehydrogenase
AAJCM20276_15620	COG0114	fumarate hydratase activity
AAJCM20276_15630	COG0840	transmembrane signaling receptor activity
AAJCM20276_15640	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AAJCM20276_15660	COG4774	siderophore transport
AAJCM20276_15690	COG1663	tetraacyldisaccharide 4'-kinase activity
AAJCM20276_15700	COG1519	Transferase
AAJCM20276_15740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AAJCM20276_15750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AAJCM20276_15760	COG0372	Belongs to the citrate synthase family
AAJCM20276_15770	COG2079	MmgE PrpD family protein
AAJCM20276_15780	COG1396	sequence-specific DNA binding
AAJCM20276_15780	COG3800	Transcriptional regulator
AAJCM20276_15850	COG2022	thiamine diphosphate biosynthetic process
AAJCM20276_15910	COG0564	pseudouridine synthase activity
AAJCM20276_15920	COG1674	ftsk spoiiie
AAJCM20276_15930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AAJCM20276_15970	COG3293	Transposase
AAJCM20276_15980	COG0583	DNA-binding transcription factor activity
AAJCM20276_15990	COG1289	transmembrane transporter activity
AAJCM20276_16000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAJCM20276_16010	COG0540	Belongs to the ATCase OTCase family
AAJCM20276_16020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AAJCM20276_16030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AAJCM20276_16040	COG0758	DNA mediated transformation
AAJCM20276_16050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AAJCM20276_16080	COG0557	exoribonuclease II activity
AAJCM20276_16090	COG0793	Belongs to the peptidase S41A family
AAJCM20276_16110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AAJCM20276_16110	COG2885	chlorophyll binding
AAJCM20276_16120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AAJCM20276_16130	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_16160	COG0187	DNA topoisomerase II activity
AAJCM20276_16180	COG0302	gtp cyclohydrolase
AAJCM20276_16190	COG2967	ApaG domain
AAJCM20276_16220	COG1215	transferase activity, transferring glycosyl groups
AAJCM20276_16250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAJCM20276_16320	COG0657	acetylesterase activity
AAJCM20276_16330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAJCM20276_16340	COG0717	Belongs to the dCTP deaminase family
AAJCM20276_16430	COG2204	response regulator
AAJCM20276_16440	COG1923	regulation of RNA biosynthetic process
AAJCM20276_16450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AAJCM20276_16470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AAJCM20276_16480	COG0450	alkyl hydroperoxide reductase
AAJCM20276_16490	COG0583	DNA-binding transcription factor activity
AAJCM20276_16520	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AAJCM20276_16540	COG0783	Belongs to the Dps family
AAJCM20276_16560	COG0142	geranyltranstransferase activity
AAJCM20276_16570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AAJCM20276_16580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AAJCM20276_16610	COG1450	Type ii and iii secretion system protein
AAJCM20276_16690	COG2062	phosphohistidine phosphatase, SixA
AAJCM20276_16700	COG1605	Chorismate mutase
AAJCM20276_16700	COG0287	Prephenate dehydrogenase
AAJCM20276_16710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AAJCM20276_16730	COG1929	Belongs to the glycerate kinase type-1 family
AAJCM20276_16740	COG1607	acyl-coa hydrolase
AAJCM20276_16770	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AAJCM20276_16780	COG0632	four-way junction helicase activity
AAJCM20276_16790	COG2255	four-way junction helicase activity
AAJCM20276_16800	COG0824	Thioesterase
AAJCM20276_16820	COG0848	biopolymer transport protein
AAJCM20276_16840	COG0823	Involved in the tonB-independent uptake of proteins
AAJCM20276_16850	COG2885	chlorophyll binding
AAJCM20276_16870	COG0037	tRNA processing
AAJCM20276_16900	COG1045	serine acetyltransferase
AAJCM20276_16910	COG2814	Major facilitator Superfamily
AAJCM20276_16960	COG0583	DNA-binding transcription factor activity
AAJCM20276_16970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AAJCM20276_16980	COG0459	protein refolding
AAJCM20276_17000	COG1196	nuclear chromosome segregation
AAJCM20276_17010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AAJCM20276_17070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AAJCM20276_17090	COG2885	chlorophyll binding
AAJCM20276_17090	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AAJCM20276_17100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AAJCM20276_17140	COG0825	malonyl-CoA metabolic process
AAJCM20276_17150	COG1546	Belongs to the CinA family
AAJCM20276_17150	COG1058	Belongs to the CinA family
AAJCM20276_17160	COG0494	nUDIX hydrolase
AAJCM20276_17190	COG1862	Preprotein translocase
AAJCM20276_17240	COG0728	peptidoglycan biosynthetic process
AAJCM20276_17270	COG4993	Dehydrogenase
AAJCM20276_17280	COG4993	Dehydrogenase
AAJCM20276_17390	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AAJCM20276_17400	COG0352	thiamine-phosphate diphosphorylase activity
AAJCM20276_17450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AAJCM20276_17460	COG1692	metallophosphoesterase
AAJCM20276_17490	COG2814	Major facilitator Superfamily
AAJCM20276_17500	COG0546	phosphoglycolate phosphatase activity
AAJCM20276_17510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AAJCM20276_17520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AAJCM20276_17530	COG0697	spore germination
AAJCM20276_17590	COG0546	phosphoglycolate phosphatase activity
AAJCM20276_17610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAJCM20276_17620	COG2003	Belongs to the UPF0758 family
AAJCM20276_17640	COG2308	Evidence 4 Homologs of previously reported genes of
AAJCM20276_17660	COG0596	Alpha beta hydrolase
AAJCM20276_17670	COG0076	glutamate decarboxylase activity
AAJCM20276_17700	COG0484	heat shock protein binding
AAJCM20276_17710	COG0271	Belongs to the BolA IbaG family
AAJCM20276_17750	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AAJCM20276_17760	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AAJCM20276_17770	COG2814	Major facilitator Superfamily
AAJCM20276_17780	COG0494	nUDIX hydrolase
AAJCM20276_17810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AAJCM20276_17860	COG0254	rRNA binding
AAJCM20276_17870	COG1970	mechanosensitive ion channel activity
AAJCM20276_17910	COG1346	cytolysis
AAJCM20276_17930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AAJCM20276_17940	COG2224	Isocitrate lyase
AAJCM20276_17950	COG1396	sequence-specific DNA binding
AAJCM20276_17950	COG3800	Transcriptional regulator
AAJCM20276_17960	COG1113	amino acid transport
AAJCM20276_17990	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AAJCM20276_18000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AAJCM20276_18010	COG3585	molybdate ion transport
AAJCM20276_18020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AAJCM20276_18030	COG0165	Argininosuccinate lyase
AAJCM20276_18040	COG3293	Transposase
AAJCM20276_18060	COG3293	Transposase
AAJCM20276_18070	COG0531	amino acid
AAJCM20276_18080	COG1968	undecaprenyl-diphosphatase activity
AAJCM20276_18130	COG2951	lytic endotransglycosylase activity
AAJCM20276_18140	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AAJCM20276_18150	COG1686	Belongs to the peptidase S11 family
AAJCM20276_18160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAJCM20276_18180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAJCM20276_18190	COG0084	hydrolase, TatD family'
AAJCM20276_18210	COG2766	serine protein kinase
AAJCM20276_18220	COG2718	Belongs to the UPF0229 family
AAJCM20276_18230	COG2719	SpoVR family
AAJCM20276_18250	COG0596	Alpha beta hydrolase
AAJCM20276_18260	COG3321	synthase
AAJCM20276_18260	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_18260	COG0604	alcohol dehydrogenase
AAJCM20276_18270	COG0045	succinate-CoA ligase (ADP-forming) activity
AAJCM20276_18320	COG3206	protein involved in exopolysaccharide biosynthesis
AAJCM20276_18320	COG0489	protein tyrosine kinase activity
AAJCM20276_18380	COG1051	belongs to the nudix hydrolase family
AAJCM20276_18400	COG0793	Belongs to the peptidase S41A family
AAJCM20276_18420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAJCM20276_18440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAJCM20276_18450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AAJCM20276_18460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AAJCM20276_18490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAJCM20276_18520	COG3008	intermembrane lipid transfer
AAJCM20276_18520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AAJCM20276_18530	COG1127	ABC transporter
AAJCM20276_18540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AAJCM20276_18550	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AAJCM20276_18560	COG2999	glutathione oxidoreductase activity
AAJCM20276_18610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AAJCM20276_18650	COG1706	bacterial-type flagellum-dependent cell motility
AAJCM20276_18680	COG0534	Mate efflux family protein
AAJCM20276_18710	COG1121	(ABC) transporter
AAJCM20276_18750	COG0659	secondary active sulfate transmembrane transporter activity
AAJCM20276_18760	COG0457	Tetratricopeptide repeat
AAJCM20276_18760	COG0859	PFAM glycosyl transferase family 9
AAJCM20276_18820	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_18890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AAJCM20276_18910	COG2226	methyltransferase
AAJCM20276_18930	COG0175	sulfate reduction
AAJCM20276_18940	COG0175	sulfate reduction
AAJCM20276_18980	COG1573	uracil-dna glycosylase
AAJCM20276_19040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAJCM20276_19080	COG0321	lipoyl(octanoyl) transferase activity
AAJCM20276_19140	COG0237	dephospho-CoA kinase activity
AAJCM20276_19150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAJCM20276_19190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AAJCM20276_19200	COG0390	transport system, permease component
AAJCM20276_19260	COG2271	Major facilitator Superfamily
AAJCM20276_19280	COG0436	Aminotransferase
AAJCM20276_19300	COG1494	fructose-1,6-bisphosphatase
AAJCM20276_19310	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AAJCM20276_19310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AAJCM20276_19340	COG3293	Transposase
AAJCM20276_19360	COG0463	Glycosyl transferase, family 2
AAJCM20276_19370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAJCM20276_19380	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAJCM20276_19390	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAJCM20276_19400	COG0356	it plays a direct role in the translocation of protons across the membrane
AAJCM20276_19440	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AAJCM20276_19480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AAJCM20276_19570	COG0432	Pfam Uncharacterised protein family UPF0047
AAJCM20276_19600	COG1132	(ABC) transporter
AAJCM20276_19620	COG1584	GPR1 FUN34 yaaH family protein
AAJCM20276_19650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AAJCM20276_19690	COG0019	diaminopimelate decarboxylase activity
AAJCM20276_19710	COG0463	Glycosyl transferase, family 2
AAJCM20276_19740	COG0539	negative regulation of cytoplasmic translation
AAJCM20276_19770	COG1289	transmembrane transporter activity
AAJCM20276_19820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAJCM20276_19830	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AAJCM20276_19840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AAJCM20276_19850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAJCM20276_19870	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AAJCM20276_19930	COG2165	general secretion pathway protein
AAJCM20276_19950	COG1459	type II secretion system
AAJCM20276_19960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AAJCM20276_20080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AAJCM20276_20100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AAJCM20276_20120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AAJCM20276_20130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AAJCM20276_20140	COG3800	Transcriptional regulator
AAJCM20276_20140	COG1396	sequence-specific DNA binding
AAJCM20276_20150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AAJCM20276_20160	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAJCM20276_20160	COG0022	dehydrogenase e1 component
AAJCM20276_20170	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAJCM20276_20180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAJCM20276_20200	COG0134	indole-3-glycerol-phosphate synthase activity
AAJCM20276_20210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AAJCM20276_20260	COG5328	Belongs to the UPF0262 family
AAJCM20276_20270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AAJCM20276_20270	COG1648	precorrin-2 dehydrogenase activity
AAJCM20276_20310	COG0861	Integral membrane protein TerC family
AAJCM20276_20320	COG0739	heme binding
AAJCM20276_20320	COG0741	lytic transglycosylase activity
AAJCM20276_20320	COG1196	nuclear chromosome segregation
AAJCM20276_20330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AAJCM20276_20340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AAJCM20276_20350	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AAJCM20276_20430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AAJCM20276_20480	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AAJCM20276_20490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAJCM20276_20500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AAJCM20276_20510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AAJCM20276_20610	COG2249	NAD(P)H dehydrogenase (quinone) activity
AAJCM20276_20620	COG0583	DNA-binding transcription factor activity
AAJCM20276_20630	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_20650	COG2072	flavoprotein involved in K transport
AAJCM20276_20680	COG2144	transferase activity, transferring acyl groups
AAJCM20276_20740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AAJCM20276_20800	COG1278	Cold shock
AAJCM20276_20810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AAJCM20276_20820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAJCM20276_20830	COG0077	Prephenate dehydratase
AAJCM20276_20830	COG1605	Chorismate mutase
AAJCM20276_20840	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AAJCM20276_20880	COG0483	inositol monophosphate 1-phosphatase activity
AAJCM20276_20890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAJCM20276_20900	COG0606	chelatase, subunit chli
AAJCM20276_20930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AAJCM20276_20970	COG1858	cytochrome C peroxidase
AAJCM20276_21090	COG2801	Transposase and inactivated derivatives
AAJCM20276_21120	COG4964	Belongs to the GSP D family
AAJCM20276_21130	COG3293	Transposase
AAJCM20276_21200	COG2132	Multicopper oxidase
AAJCM20276_21230	COG1566	PFAM secretion protein HlyD family protein
AAJCM20276_21280	COG0837	glucose binding
AAJCM20276_21290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AAJCM20276_21320	COG0525	valine-tRNA ligase activity
AAJCM20276_21330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAJCM20276_21360	COG3293	Transposase
AAJCM20276_21390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AAJCM20276_21410	COG0752	glycyl-tRNA synthetase alpha subunit
AAJCM20276_21450	COG2801	Transposase and inactivated derivatives
AAJCM20276_21480	COG0583	DNA-binding transcription factor activity
AAJCM20276_21550	COG0789	Transcriptional regulator
AAJCM20276_21580	COG0477	Major facilitator Superfamily
AAJCM20276_21600	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAJCM20276_21610	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AAJCM20276_21630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAJCM20276_21640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAJCM20276_21690	COG2995	paraquat-inducible protein a
AAJCM20276_21770	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AAJCM20276_21780	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AAJCM20276_21800	COG0535	radical SAM domain protein
AAJCM20276_21830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAJCM20276_21840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAJCM20276_21860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AAJCM20276_21910	COG3590	peptidase
AAJCM20276_21940	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AAJCM20276_21950	COG1764	response to oxidative stress
AAJCM20276_21970	COG3511	phospholipase C
AAJCM20276_21980	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AAJCM20276_21990	COG2894	cell division
AAJCM20276_22000	COG0850	regulation of cytokinetic process
AAJCM20276_22020	COG0402	S-adenosylhomocysteine deaminase activity
AAJCM20276_22030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_22060	COG3608	succinylglutamate desuccinylase aspartoacylase
AAJCM20276_22060	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AAJCM20276_22090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAJCM20276_22180	COG1278	Cold shock
AAJCM20276_22190	COG1393	Belongs to the ArsC family
AAJCM20276_22200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAJCM20276_22250	COG1160	GTP binding
AAJCM20276_22260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAJCM20276_22330	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_22370	COG3293	Transposase
AAJCM20276_22400	COG3306	glycosyltransferase involved in LPS biosynthesis
AAJCM20276_22460	COG2267	carboxylic ester hydrolase activity
AAJCM20276_22480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAJCM20276_22480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAJCM20276_22500	COG0747	negative chemotaxis
AAJCM20276_22510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAJCM20276_22540	COG4608	Belongs to the ABC transporter superfamily
AAJCM20276_22560	COG3293	Transposase
AAJCM20276_22580	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AAJCM20276_22600	COG3335	DDE superfamily endonuclease
AAJCM20276_22640	COG1045	serine acetyltransferase
AAJCM20276_22700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AAJCM20276_22710	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AAJCM20276_22720	COG4208	sulfate ABC transporter
AAJCM20276_22730	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AAJCM20276_22750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AAJCM20276_22770	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_22830	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_22840	COG1120	ATPase activity
AAJCM20276_22890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AAJCM20276_22890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAJCM20276_22910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AAJCM20276_22930	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_22950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAJCM20276_22960	COG2171	N-acyltransferase activity
AAJCM20276_22970	COG2199	diguanylate cyclase activity
AAJCM20276_22990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AAJCM20276_23000	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAJCM20276_23010	COG0154	amidase activity
AAJCM20276_23020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAJCM20276_23030	COG2264	protein methyltransferase activity
AAJCM20276_23040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AAJCM20276_23050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAJCM20276_23060	COG1518	maintenance of DNA repeat elements
AAJCM20276_23090	COG1857	crispr-associated protein
AAJCM20276_23120	COG1203	CRISPR-associated helicase, Cas3
AAJCM20276_23130	COG1132	(ABC) transporter
AAJCM20276_23140	COG0617	tRNA 3'-terminal CCA addition
AAJCM20276_23160	COG0714	Associated with various cellular activities
AAJCM20276_23200	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AAJCM20276_23220	COG1185	polyribonucleotide nucleotidyltransferase activity
AAJCM20276_23230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AAJCM20276_23240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AAJCM20276_23250	COG0739	heme binding
AAJCM20276_23250	COG1196	nuclear chromosome segregation
AAJCM20276_23250	COG0741	lytic transglycosylase activity
AAJCM20276_23270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AAJCM20276_23280	COG1686	Belongs to the peptidase S11 family
AAJCM20276_23290	COG2890	protein-(glutamine-N5) methyltransferase activity
AAJCM20276_23310	COG0277	FAD linked oxidase domain protein
AAJCM20276_23370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAJCM20276_23380	COG1702	phosphate starvation-inducible protein PhoH
AAJCM20276_23390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AAJCM20276_23440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AAJCM20276_23460	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AAJCM20276_23470	COG0268	Binds directly to 16S ribosomal RNA
AAJCM20276_23480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AAJCM20276_23490	COG2226	methyltransferase
AAJCM20276_23510	COG0756	dUTP diphosphatase activity
AAJCM20276_23530	COG1116	anion transmembrane transporter activity
AAJCM20276_23550	COG0612	Peptidase, M16
AAJCM20276_23560	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_23570	COG3264	Mechanosensitive ion channel
AAJCM20276_23570	COG1511	domain protein
AAJCM20276_23580	COG1297	OPT oligopeptide transporter protein
AAJCM20276_23610	COG2217	Heavy metal translocating P-type atpase
AAJCM20276_23650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAJCM20276_23660	COG1621	beta-fructofuranosidase activity
AAJCM20276_23690	COG1032	radical SAM domain protein
AAJCM20276_23730	COG1414	Transcriptional regulator
AAJCM20276_23750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AAJCM20276_23790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AAJCM20276_23850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AAJCM20276_23860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AAJCM20276_23860	COG5373	membrane
AAJCM20276_23890	COG0779	Required for maturation of 30S ribosomal subunits
AAJCM20276_23910	COG0542	response to heat
AAJCM20276_23930	COG0583	DNA-binding transcription factor activity
AAJCM20276_23940	COG0765	amino acid transport
AAJCM20276_23950	COG1126	abc transporter atp-binding protein
AAJCM20276_23960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AAJCM20276_23970	COG4133	protoheme IX ABC transporter activity
AAJCM20276_23980	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAJCM20276_23990	COG1253	flavin adenine dinucleotide binding
AAJCM20276_24000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAJCM20276_24010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAJCM20276_24020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAJCM20276_24030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAJCM20276_24070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAJCM20276_24080	COG3394	polysaccharide catabolic process
AAJCM20276_24100	COG2945	thiolester hydrolase activity
AAJCM20276_24110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AAJCM20276_24130	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AAJCM20276_24130	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AAJCM20276_24150	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AAJCM20276_24180	COG0523	cobalamin synthesis protein
AAJCM20276_24210	COG0590	tRNA wobble adenosine to inosine editing
AAJCM20276_24220	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AAJCM20276_24230	COG1187	pseudouridine synthase activity
AAJCM20276_24240	COG0742	ribosomal rna small subunit methyltransferase
AAJCM20276_24270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AAJCM20276_24280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AAJCM20276_24300	COG4206	TonB-dependent receptor
AAJCM20276_24310	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AAJCM20276_24320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AAJCM20276_24410	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AAJCM20276_24420	COG0386	Belongs to the glutathione peroxidase family
AAJCM20276_24440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAJCM20276_24470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAJCM20276_24480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAJCM20276_24490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AAJCM20276_24610	COG0306	phosphate transporter
AAJCM20276_24620	COG3217	Mosc domain protein beta barrel domain protein
AAJCM20276_24620	COG0633	Ferredoxin
AAJCM20276_24630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AAJCM20276_24660	COG0149	triose-phosphate isomerase activity
AAJCM20276_24690	COG0504	CTP synthase activity
AAJCM20276_24700	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AAJCM20276_24720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AAJCM20276_24740	COG0217	transcriptional regulatory protein
AAJCM20276_24750	COG0653	protein targeting
AAJCM20276_24760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAJCM20276_24770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AAJCM20276_24780	COG1714	RDD family
AAJCM20276_24790	COG0668	transmembrane transport
AAJCM20276_24820	COG4771	TonB-dependent receptor
AAJCM20276_24830	COG0583	DNA-binding transcription factor activity
AAJCM20276_24840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_24900	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AAJCM20276_24930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AAJCM20276_24940	COG1127	ABC transporter
AAJCM20276_24950	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AAJCM20276_25000	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AAJCM20276_25010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AAJCM20276_25040	COG3293	Transposase
AAJCM20276_25050	COG2003	Belongs to the UPF0758 family
AAJCM20276_25060	COG2814	Major facilitator Superfamily
AAJCM20276_25070	COG1566	PFAM secretion protein HlyD family protein
AAJCM20276_25100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AAJCM20276_25150	COG1987	bacterial-type flagellum assembly
AAJCM20276_25160	COG1677	Flagellar hook-basal body complex protein FliE
AAJCM20276_25170	COG1558	bacterial-type flagellum-dependent cell motility
AAJCM20276_25180	COG1815	bacterial-type flagellum-dependent cell motility
AAJCM20276_25200	COG1338	Plays a role in the flagellum-specific transport system
AAJCM20276_25210	COG1136	(ABC) transporter
AAJCM20276_25230	COG0442	prolyl-tRNA aminoacylation
AAJCM20276_25260	COG0493	'glutamate synthase
AAJCM20276_25300	COG1953	Uracil, thiamine, allantoin
AAJCM20276_25330	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AAJCM20276_25350	COG1007	ATP synthesis coupled electron transport
AAJCM20276_25390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_25400	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AAJCM20276_25410	COG1034	ATP synthesis coupled electron transport
AAJCM20276_25430	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AAJCM20276_25440	COG0649	NAD binding
AAJCM20276_25450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_25460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_25470	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_25480	COG0776	regulation of translation
AAJCM20276_25500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AAJCM20276_25510	COG0740	serine-type endopeptidase activity
AAJCM20276_25520	COG0544	peptidyl-prolyl cis-trans isomerase activity
AAJCM20276_25530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AAJCM20276_25530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AAJCM20276_25550	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_25620	COG2814	Major facilitator Superfamily
AAJCM20276_25680	COG5001	Diguanylate cyclase
AAJCM20276_25680	COG3300	MHYT domain
AAJCM20276_25690	COG3300	MHYT domain
AAJCM20276_25690	COG5001	Diguanylate cyclase
AAJCM20276_25700	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AAJCM20276_25720	COG3265	gluconokinase activity
AAJCM20276_25730	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AAJCM20276_25740	COG0363	glucosamine-6-phosphate deaminase activity
AAJCM20276_25750	COG0561	phosphatase activity
AAJCM20276_25760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AAJCM20276_25770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AAJCM20276_25800	COG1570	exodeoxyribonuclease VII activity
AAJCM20276_25820	COG0179	Fumarylacetoacetate (FAA) hydrolase
AAJCM20276_25830	COG1216	Glycosyl transferase, family 2
AAJCM20276_25830	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_25850	COG1657	PFAM Prenyltransferase squalene oxidase
AAJCM20276_25860	COG1233	COG1233 Phytoene dehydrogenase and related
AAJCM20276_25870	COG1562	ergosterol biosynthetic process
AAJCM20276_25880	COG1562	ergosterol biosynthetic process
AAJCM20276_25890	COG2816	NAD+ diphosphatase activity
AAJCM20276_25910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AAJCM20276_25930	COG0287	Prephenate dehydrogenase
AAJCM20276_25960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAJCM20276_25980	COG0109	protoheme IX farnesyltransferase activity
AAJCM20276_26000	COG2226	methyltransferase
AAJCM20276_26010	COG0189	ligase activity
AAJCM20276_26030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AAJCM20276_26040	COG1360	Flagellar Motor Protein
AAJCM20276_26070	COG1522	sequence-specific DNA binding
AAJCM20276_26090	COG0492	ferredoxin-NADP+ reductase activity
AAJCM20276_26100	COG0583	DNA-binding transcription factor activity
AAJCM20276_26110	COG1321	iron dependent repressor
AAJCM20276_26180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAJCM20276_26200	COG0616	signal peptide processing
AAJCM20276_26210	COG0776	regulation of translation
AAJCM20276_26230	COG0662	Cupin 2, conserved barrel domain protein
AAJCM20276_26230	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AAJCM20276_26270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AAJCM20276_26280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AAJCM20276_26300	COG1607	acyl-coa hydrolase
AAJCM20276_26310	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AAJCM20276_26320	COG0354	folic acid binding
AAJCM20276_26330	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AAJCM20276_26340	COG0242	peptide deformylase activity
AAJCM20276_26360	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AAJCM20276_26370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAJCM20276_26380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAJCM20276_26400	COG1722	exodeoxyribonuclease VII activity
AAJCM20276_26460	COG1940	carbohydrate kinase activity
AAJCM20276_26470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAJCM20276_26480	COG0316	Belongs to the HesB IscA family
AAJCM20276_26490	COG2151	metal-sulfur cluster biosynthetic enzyme
AAJCM20276_26510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAJCM20276_26520	COG0719	Fe-S assembly protein
AAJCM20276_26530	COG0396	ATPase activity
AAJCM20276_26540	COG0719	Fe-S assembly protein
AAJCM20276_26550	COG1959	2 iron, 2 sulfur cluster binding
AAJCM20276_26570	COG2733	membrane
AAJCM20276_26610	COG0156	8-amino-7-oxononanoate synthase activity
AAJCM20276_26650	COG0126	phosphoglycerate kinase activity
AAJCM20276_27050	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AAJCM20276_27260	COG3728	DNA packaging
AAJCM20276_27260	COG5484	DNA packaging
AAJCM20276_27330	COG1061	Type III restriction enzyme res subunit
AAJCM20276_27630	COG2801	Transposase and inactivated derivatives
AAJCM20276_27690	COG2205	protein histidine kinase activity
AAJCM20276_27750	COG2223	nitrite transmembrane transporter activity
AAJCM20276_27770	COG2146	nitrite reductase [NAD(P)H] activity
AAJCM20276_27770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AAJCM20276_27780	COG0243	molybdopterin cofactor binding
AAJCM20276_27800	COG1116	anion transmembrane transporter activity
AAJCM20276_27800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAJCM20276_27830	COG0803	Belongs to the bacterial solute-binding protein 9 family
AAJCM20276_27870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AAJCM20276_27880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AAJCM20276_27900	COG5265	(ABC) transporter
AAJCM20276_27950	COG0596	Alpha beta hydrolase
AAJCM20276_27950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAJCM20276_27950	COG2226	methyltransferase
AAJCM20276_28010	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AAJCM20276_28010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AAJCM20276_28020	COG0737	Belongs to the 5'-nucleotidase family
AAJCM20276_28030	COG3572	ergothioneine biosynthetic process
AAJCM20276_28050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AAJCM20276_28070	COG0513	Belongs to the DEAD box helicase family
AAJCM20276_28080	COG4106	trans-aconitate 2-methyltransferase activity
AAJCM20276_28080	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AAJCM20276_28100	COG0156	8-amino-7-oxononanoate synthase activity
AAJCM20276_28120	COG0314	molybdopterin synthase activity
AAJCM20276_28130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AAJCM20276_28150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAJCM20276_28160	COG0322	excinuclease ABC activity
AAJCM20276_28190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAJCM20276_28220	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_28270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AAJCM20276_28310	COG1216	Glycosyl transferase, family 2
AAJCM20276_28310	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_28340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAJCM20276_28380	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AAJCM20276_28390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AAJCM20276_28400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AAJCM20276_28410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AAJCM20276_28420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AAJCM20276_28430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AAJCM20276_28440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAJCM20276_28460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AAJCM20276_28490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AAJCM20276_28510	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AAJCM20276_28520	COG1053	succinate dehydrogenase
AAJCM20276_28530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AAJCM20276_28560	COG2824	Alkylphosphonate utilization operon protein PhnA
AAJCM20276_28580	COG3920	Histidine kinase
AAJCM20276_28580	COG2202	Pas domain
AAJCM20276_28600	COG0488	(ABC) transporter
AAJCM20276_28620	COG0628	permease
AAJCM20276_28690	COG0006	proline dipeptidase activity
AAJCM20276_28700	COG0473	3-isopropylmalate dehydrogenase activity
AAJCM20276_28740	COG2801	Transposase and inactivated derivatives
AAJCM20276_28750	COG3293	Transposase
AAJCM20276_28810	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AAJCM20276_28820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAJCM20276_28820	COG0072	phenylalanine-tRNA ligase activity
AAJCM20276_28830	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AAJCM20276_28840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AAJCM20276_28890	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AAJCM20276_28900	COG3706	GGDEF domain
AAJCM20276_28900	COG4251	negative regulation of phosphorylation
AAJCM20276_28900	COG5001	Diguanylate cyclase
AAJCM20276_28900	COG2203	Gaf domain
AAJCM20276_28940	COG0612	Peptidase, M16
AAJCM20276_28950	COG0312	modulator of DNA gyrase
AAJCM20276_28970	COG2755	lipolytic protein G-D-S-L family
AAJCM20276_28970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AAJCM20276_28980	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AAJCM20276_28990	COG1454	alcohol dehydrogenase
AAJCM20276_29000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AAJCM20276_29000	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AAJCM20276_29010	COG0194	GDP metabolic process
AAJCM20276_29020	COG0300	oxidoreductase activity
AAJCM20276_29030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AAJCM20276_29150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAJCM20276_29230	COG0415	Belongs to the DNA photolyase family
AAJCM20276_29320	COG1566	PFAM secretion protein HlyD family protein
AAJCM20276_29450	COG0586	Pfam SNARE associated Golgi protein
AAJCM20276_29460	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_29470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAJCM20276_29490	COG0140	phosphoribosyl-ATP diphosphatase activity
AAJCM20276_29500	COG0107	imidazoleglycerol-phosphate synthase activity
AAJCM20276_29510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AAJCM20276_29520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AAJCM20276_29540	COG0131	Imidazoleglycerol-phosphate dehydratase
AAJCM20276_29550	COG5001	Diguanylate cyclase
AAJCM20276_29550	COG3300	MHYT domain
AAJCM20276_29630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AAJCM20276_29680	COG1199	ATP-dependent helicase activity
AAJCM20276_29770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAJCM20276_29870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AAJCM20276_29880	COG0531	amino acid
AAJCM20276_29890	COG1253	flavin adenine dinucleotide binding
AAJCM20276_29900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AAJCM20276_29910	COG1671	Belongs to the UPF0178 family
AAJCM20276_29940	COG1597	lipid kinase activity
AAJCM20276_29960	COG2326	polyphosphate kinase activity
AAJCM20276_29970	COG4221	oxidoreductase activity
AAJCM20276_29980	COG1678	Uncharacterized ACR, COG1678
AAJCM20276_30030	COG1217	gtp-binding protein TYPA
AAJCM20276_30100	COG2818	Glycosylase
AAJCM20276_30110	COG0473	3-isopropylmalate dehydrogenase activity
AAJCM20276_30130	COG1335	isochorismatase
AAJCM20276_30150	COG0583	DNA-binding transcription factor activity
AAJCM20276_30160	COG1289	transmembrane transporter activity
AAJCM20276_30170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAJCM20276_30190	COG2814	Major facilitator Superfamily
AAJCM20276_30220	COG1612	heme a metabolic process
AAJCM20276_30290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AAJCM20276_30320	COG3293	Transposase
AAJCM20276_30360	COG0489	protein tyrosine kinase activity
AAJCM20276_30390	COG0741	lytic transglycosylase activity
AAJCM20276_30400	COG1573	uracil-dna glycosylase
AAJCM20276_30430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AAJCM20276_30440	COG0066	3-isopropylmalate dehydratase activity
AAJCM20276_30460	COG0778	Nitroreductase
AAJCM20276_30470	COG3042	response to heat
AAJCM20276_30490	COG0581	inorganic phosphate transmembrane transporter activity
AAJCM20276_30500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AAJCM20276_30520	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_30540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AAJCM20276_30560	COG0335	large ribosomal subunit rRNA binding
AAJCM20276_30570	COG0336	Belongs to the RNA methyltransferase TrmD family
AAJCM20276_30580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AAJCM20276_30590	COG0228	four-way junction DNA binding
AAJCM20276_30660	COG0347	Belongs to the P(II) protein family
AAJCM20276_30670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AAJCM20276_30700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAJCM20276_30730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AAJCM20276_30740	COG1942	4-Oxalocrotonate Tautomerase
AAJCM20276_30760	COG4303	Ethanolamine ammonia lyase large subunit
AAJCM20276_30770	COG4302	ethanolamine ammonia-lyase activity
AAJCM20276_30780	COG0531	amino acid
AAJCM20276_30810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AAJCM20276_30830	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AAJCM20276_30850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AAJCM20276_30910	COG3660	Nucleoside-diphosphate-sugar epimerase
AAJCM20276_30920	COG0148	phosphopyruvate hydratase activity
AAJCM20276_30940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AAJCM20276_30950	COG0303	'Molybdopterin
AAJCM20276_30980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AAJCM20276_30990	COG0285	dihydrofolate synthase activity
AAJCM20276_31020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AAJCM20276_31040	COG1177	transmembrane transport
AAJCM20276_31050	COG1176	ABC-type spermidine putrescine transport system, permease component I
AAJCM20276_31060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AAJCM20276_31070	COG3842	ATPase activity
AAJCM20276_31130	COG0848	biopolymer transport protein
AAJCM20276_31160	COG4774	siderophore transport
AAJCM20276_31170	COG3128	pkhd-type hydroxylase
AAJCM20276_31190	COG0167	dihydroorotate dehydrogenase activity
AAJCM20276_31200	COG5487	UPF0391 membrane protein
AAJCM20276_31220	COG1116	anion transmembrane transporter activity
AAJCM20276_31250	COG0203	ribosomal protein L17
AAJCM20276_31260	COG0202	RNA polymerase activity
AAJCM20276_31270	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AAJCM20276_31280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AAJCM20276_31290	COG0563	adenylate kinase activity
AAJCM20276_31300	COG0201	protein transport
AAJCM20276_31310	COG0200	Binds to the 23S rRNA
AAJCM20276_31320	COG1841	ribosomal large subunit assembly
AAJCM20276_31330	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AAJCM20276_31340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AAJCM20276_31350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AAJCM20276_31360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AAJCM20276_31370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AAJCM20276_31380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAJCM20276_31390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AAJCM20276_31400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AAJCM20276_31410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AAJCM20276_31420	COG0255	Belongs to the universal ribosomal protein uL29 family
AAJCM20276_31430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AAJCM20276_31440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AAJCM20276_31450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AAJCM20276_31460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AAJCM20276_31470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAJCM20276_31480	COG0089	rRNA binding
AAJCM20276_31490	COG0088	Forms part of the polypeptide exit tunnel
AAJCM20276_31500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AAJCM20276_31510	COG0051	transcription antitermination factor activity, RNA binding
AAJCM20276_31520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAJCM20276_31530	COG0049	tRNA binding
AAJCM20276_31540	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AAJCM20276_31560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAJCM20276_31580	COG0085	RNA polymerase activity
AAJCM20276_31590	COG0222	ribosome binding
AAJCM20276_31600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AAJCM20276_31610	COG0081	regulation of translation
AAJCM20276_31620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AAJCM20276_31650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAJCM20276_31660	COG0235	Class ii aldolase
AAJCM20276_31670	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AAJCM20276_31680	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AAJCM20276_31690	COG0196	riboflavin kinase activity
AAJCM20276_31710	COG4716	Myosin-crossreactive antigen
AAJCM20276_31730	COG3415	Transposase
AAJCM20276_31770	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_31780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_31790	COG0649	NAD binding
AAJCM20276_31790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_31830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AAJCM20276_31840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAJCM20276_31850	COG0839	Belongs to the complex I subunit 6 family
AAJCM20276_31860	COG0713	ATP synthesis coupled electron transport
AAJCM20276_31890	COG1007	ATP synthesis coupled electron transport
AAJCM20276_31900	COG0516	GMP reductase activity
AAJCM20276_31900	COG0517	IMP dehydrogenase activity
AAJCM20276_31960	COG4993	Dehydrogenase
AAJCM20276_31980	COG2010	Cytochrome c
AAJCM20276_32050	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AAJCM20276_32060	COG2943	transferase activity, transferring hexosyl groups
AAJCM20276_32090	COG0658	competence protein
AAJCM20276_32090	COG2333	competence protein COMEC
AAJCM20276_32130	COG0483	inositol monophosphate 1-phosphatase activity
AAJCM20276_32140	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AAJCM20276_32160	COG0776	regulation of translation
AAJCM20276_32170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AAJCM20276_32180	COG0416	fatty acid biosynthetic process
AAJCM20276_32190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AAJCM20276_32230	COG0745	RESPONSE REGULATOR receiver
AAJCM20276_32260	COG0242	peptide deformylase activity
AAJCM20276_32280	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AAJCM20276_32400	COG0646	methionine synthase
AAJCM20276_32400	COG1410	methionine synthase
AAJCM20276_32410	COG3293	Transposase
AAJCM20276_32420	COG2132	Multicopper oxidase
AAJCM20276_32440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AAJCM20276_32450	COG0492	ferredoxin-NADP+ reductase activity
AAJCM20276_32460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_32470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AAJCM20276_32480	COG2814	Major facilitator Superfamily
AAJCM20276_32530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AAJCM20276_32550	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AAJCM20276_32570	COG0598	Magnesium transport protein CorA
AAJCM20276_32590	COG1091	dTDP-4-dehydrorhamnose reductase activity
AAJCM20276_32610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AAJCM20276_32650	COG0583	DNA-binding transcription factor activity
AAJCM20276_32660	COG1028	Short-chain dehydrogenase reductase Sdr
AAJCM20276_32690	COG0523	cobalamin synthesis protein
AAJCM20276_32720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AAJCM20276_32730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAJCM20276_32750	COG2814	Major facilitator Superfamily
AAJCM20276_32790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AAJCM20276_32810	COG2897	thiosulfate sulfurtransferase activity
AAJCM20276_32830	COG0628	permease
AAJCM20276_32860	COG3047	cAMP biosynthetic process
AAJCM20276_32870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAJCM20276_32890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AAJCM20276_32910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AAJCM20276_32970	COG2814	Major facilitator Superfamily
AAJCM20276_33010	COG3293	Transposase
AAJCM20276_33060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AAJCM20276_33080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_33100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_33110	COG2113	Glycine betaine
AAJCM20276_33120	COG3448	diguanylate cyclase activity
AAJCM20276_33120	COG4175	Glycine betaine
AAJCM20276_33130	COG4176	ABC-type proline glycine betaine transport system permease component
AAJCM20276_33170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAJCM20276_33200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AAJCM20276_33200	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAJCM20276_33210	COG4311	Sarcosine oxidase, delta subunit
AAJCM20276_33220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_33250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AAJCM20276_33260	COG2218	PFAM glutamate synthase alpha subunit domain protein
AAJCM20276_33270	COG0069	glutamate synthase activity
AAJCM20276_33300	COG0004	ammonium transporteR
AAJCM20276_33310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_33350	COG2801	Transposase and inactivated derivatives
AAJCM20276_33400	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AAJCM20276_33650	COG0583	DNA-binding transcription factor activity
AAJCM20276_33720	COG3344	reverse transcriptase
AAJCM20276_33740	COG2801	Transposase and inactivated derivatives
AAJCM20276_33810	COG0439	Biotin carboxylase
AAJCM20276_33830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AAJCM20276_33840	COG1984	allophanate hydrolase subunit 2
AAJCM20276_33860	COG2271	Major facilitator Superfamily
AAJCM20276_33880	COG2271	Major facilitator Superfamily
AAJCM20276_33910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAJCM20276_33960	COG3344	reverse transcriptase
AAJCM20276_34020	COG0438	transferase activity, transferring glycosyl groups
AAJCM20276_34080	COG3335	DDE superfamily endonuclease
AAJCM20276_34110	COG4735	regulation of single-species biofilm formation
AAJCM20276_34140	COG3293	Transposase
AAJCM20276_34160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AAJCM20276_34340	COG3550	peptidyl-serine autophosphorylation
AAJCM20276_34400	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_34410	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_34470	COG2755	lipolytic protein G-D-S-L family
AAJCM20276_34470	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AAJCM20276_34500	COG0251	oxidation-reduction process
AAJCM20276_34510	COG0604	alcohol dehydrogenase
AAJCM20276_34530	COG3293	Transposase
AAJCM20276_34570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAJCM20276_34610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAJCM20276_34670	COG0495	leucyl-tRNA aminoacylation
AAJCM20276_34700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AAJCM20276_34710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAJCM20276_34730	COG0018	arginyl-trna synthetase
AAJCM20276_34760	COG1368	sulfuric ester hydrolase activity
AAJCM20276_34770	COG2226	methyltransferase
AAJCM20276_34790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAJCM20276_34800	COG0318	PFAM AMP-dependent synthetase and ligase
AAJCM20276_34930	COG0656	L-ascorbic acid biosynthetic process
AAJCM20276_34950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AAJCM20276_34970	COG2814	Major facilitator Superfamily
AAJCM20276_34990	COG0009	L-threonylcarbamoyladenylate synthase
AAJCM20276_35030	COG0305	Participates in initiation and elongation during chromosome replication
AAJCM20276_35060	COG1289	transmembrane transporter activity
AAJCM20276_35090	COG1492	cobalamin metabolic process
AAJCM20276_35110	COG1797	cobyrinic acid a,c-diamide synthase activity
AAJCM20276_35180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AAJCM20276_35200	COG1194	a g-specific adenine glycosylase
AAJCM20276_35230	COG1012	belongs to the aldehyde dehydrogenase family
AAJCM20276_35240	COG0753	catalase activity
AAJCM20276_35280	COG1960	acyl-CoA dehydrogenase activity
AAJCM20276_35290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAJCM20276_35300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAJCM20276_35310	COG1116	anion transmembrane transporter activity
AAJCM20276_35360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAJCM20276_35490	COG3547	Transposase (IS116 IS110 IS902 family)
AAJCM20276_35550	COG1216	Glycosyl transferase, family 2
AAJCM20276_35610	COG3436	PFAM IS66 Orf2 family protein
AAJCM20276_35620	COG4372	Transposase
AAJCM20276_35630	COG4372	Transposase
AAJCM20276_35640	COG4372	Transposase
AAJCM20276_35660	COG3415	Transposase
AAJCM20276_35750	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AAJCM20276_35780	COG3415	Transposase
AAJCM20276_35790	COG3335	DDE superfamily endonuclease
AAJCM20276_35820	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAJCM20276_35910	COG2801	Transposase and inactivated derivatives
AAJCM20276_36010	COG4372	Transposase
AAJCM20276_36020	COG3436	PFAM IS66 Orf2 family protein
AAJCM20276_36140	COG1476	TRANSCRIPTIONal
AAJCM20276_36190	COG3344	reverse transcriptase
AAJCM20276_36200	COG3344	reverse transcriptase
AAJCM20276_36240	COG4974	Belongs to the 'phage' integrase family
AAJCM20276_36300	COG1192	Involved in chromosome partitioning
AAJCM20276_36340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AAJCM20276_36560	COG3831	ATPase activity
AAJCM20276_36600	COG1475	DNA binding
AAJCM20276_36820	COG3344	reverse transcriptase
AAJCM20276_36920	COG2184	nucleotidyltransferase activity
AAJCM20276_36990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAJCM20276_37010	COG3547	Transposase (IS116 IS110 IS902 family)
AAJCM20276_37090	COG3415	Transposase
AAJCM20276_37110	COG3335	DDE superfamily endonuclease
AAJCM20276_37160	COG2132	Multicopper oxidase
AAJCM20276_37170	COG1937	Protein conserved in bacteria
AAJCM20276_37180	COG2217	Heavy metal translocating P-type atpase
AAJCM20276_37210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AAJCM20276_37340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAJCM20276_37390	COG0789	Transcriptional regulator
AAJCM20276_37480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAJCM20276_37600	COG4644	lycopene metabolic process
AAJCM20276_37640	COG1002	Type II restriction enzyme, methylase subunits
AAJCM20276_37720	COG4115	mRNA cleavage
AAJCM20276_37730	COG2161	toxin-antitoxin pair type II binding