locus-tag	class	description
EMQ_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EMQ_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EMQ_0008	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EMQ_0009	COG1702	phosphate starvation-inducible protein PhoH
EMQ_0010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EMQ_0015	COG0277	FAD linked oxidase domain protein
EMQ_0017	COG2890	protein-(glutamine-N5) methyltransferase activity
EMQ_0018	COG1686	Belongs to the peptidase S11 family
EMQ_0019	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EMQ_0021	COG1196	nuclear chromosome segregation
EMQ_0021	COG0741	lytic transglycosylase activity
EMQ_0021	COG0739	heme binding
EMQ_0022	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EMQ_0023	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EMQ_0024	COG1185	polyribonucleotide nucleotidyltransferase activity
EMQ_0026	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EMQ_0030	COG0714	Associated with various cellular activities
EMQ_0032	COG0617	tRNA 3'-terminal CCA addition
EMQ_0033	COG1132	(ABC) transporter
EMQ_0034	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EMQ_0035	COG2264	protein methyltransferase activity
EMQ_0036	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EMQ_0037	COG0154	amidase activity
EMQ_0038	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EMQ_0039	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EMQ_0041	COG2199	diguanylate cyclase activity
EMQ_0042	COG2171	N-acyltransferase activity
EMQ_0043	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EMQ_0045	COG0438	transferase activity, transferring glycosyl groups
EMQ_0047	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EMQ_0054	COG1120	ATPase activity
EMQ_0055	COG1012	belongs to the aldehyde dehydrogenase family
EMQ_0061	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_0064	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EMQ_0066	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EMQ_0067	COG4208	sulfate ABC transporter
EMQ_0068	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EMQ_0069	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EMQ_0075	COG1045	serine acetyltransferase
EMQ_0077	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EMQ_0078	COG4608	Belongs to the ABC transporter superfamily
EMQ_0081	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EMQ_0082	COG0747	negative chemotaxis
EMQ_0084	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EMQ_0084	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EMQ_0090	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_0098	COG1160	GTP binding
EMQ_0103	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EMQ_0104	COG1393	Belongs to the ArsC family
EMQ_0105	COG1278	Cold shock
EMQ_0112	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EMQ_0115	COG3608	succinylglutamate desuccinylase aspartoacylase
EMQ_0115	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EMQ_0118	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EMQ_0119	COG0402	S-adenosylhomocysteine deaminase activity
EMQ_0121	COG0850	regulation of cytokinetic process
EMQ_0122	COG2894	cell division
EMQ_0123	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EMQ_0124	COG3511	phospholipase C
EMQ_0126	COG1764	response to oxidative stress
EMQ_0127	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EMQ_0130	COG3590	peptidase
EMQ_0135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EMQ_0137	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMQ_0138	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EMQ_0141	COG0535	radical SAM domain protein
EMQ_0143	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
EMQ_0144	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EMQ_0152	COG2995	paraquat-inducible protein a
EMQ_0157	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EMQ_0158	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMQ_0160	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EMQ_0161	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EMQ_0163	COG0477	Major facilitator Superfamily
EMQ_0167	COG0751	glycine-tRNA ligase activity
EMQ_0168	COG0752	glycyl-tRNA synthetase alpha subunit
EMQ_0170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EMQ_0173	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EMQ_0174	COG0525	valine-tRNA ligase activity
EMQ_0177	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EMQ_0178	COG0837	glucose binding
EMQ_0183	COG1566	PFAM secretion protein HlyD family protein
EMQ_0187	COG2132	Multicopper oxidase
EMQ_0192	COG4964	Belongs to the GSP D family
EMQ_0202	COG1858	cytochrome C peroxidase
EMQ_0206	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EMQ_0209	COG0606	chelatase, subunit chli
EMQ_0210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EMQ_0211	COG0483	inositol monophosphate 1-phosphatase activity
EMQ_0215	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EMQ_0216	COG0077	Prephenate dehydratase
EMQ_0216	COG1605	Chorismate mutase
EMQ_0217	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EMQ_0218	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EMQ_0219	COG1278	Cold shock
EMQ_0222	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EMQ_0227	COG2144	transferase activity, transferring acyl groups
EMQ_0230	COG2072	flavoprotein involved in K transport
EMQ_0232	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_0233	COG0583	DNA-binding transcription factor activity
EMQ_0234	COG2249	NAD(P)H dehydrogenase (quinone) activity
EMQ_0249	COG0583	DNA-binding transcription factor activity
EMQ_0264	COG2217	Heavy metal translocating P-type atpase
EMQ_0265	COG1937	Protein conserved in bacteria
EMQ_0266	COG2132	Multicopper oxidase
EMQ_0273	COG1335	isochorismatase
EMQ_0274	COG2814	Major facilitator Superfamily
EMQ_0277	COG3293	Transposase
EMQ_0288	COG3685	Protein conserved in bacteria
EMQ_0290	COG1012	belongs to the aldehyde dehydrogenase family
EMQ_0291	COG1902	pentaerythritol trinitrate reductase activity
EMQ_0292	COG1733	regulation of RNA biosynthetic process
EMQ_0295	COG1733	regulation of RNA biosynthetic process
EMQ_0305	COG0582	viral genome integration into host DNA
EMQ_0306	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EMQ_0307	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EMQ_0308	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EMQ_0309	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EMQ_0314	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EMQ_0320	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EMQ_0321	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EMQ_0322	COG0741	lytic transglycosylase activity
EMQ_0322	COG0739	heme binding
EMQ_0322	COG1196	nuclear chromosome segregation
EMQ_0323	COG0861	Integral membrane protein TerC family
EMQ_0327	COG1648	precorrin-2 dehydrogenase activity
EMQ_0327	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EMQ_0328	COG5328	Belongs to the UPF0262 family
EMQ_0333	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EMQ_0334	COG0134	indole-3-glycerol-phosphate synthase activity
EMQ_0335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EMQ_0336	COG0508	dehydrogenase complex catalyzes the overall conversion of
EMQ_0337	COG0022	dehydrogenase e1 component
EMQ_0337	COG0508	dehydrogenase complex catalyzes the overall conversion of
EMQ_0338	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EMQ_0339	COG1396	sequence-specific DNA binding
EMQ_0339	COG3800	Transcriptional regulator
EMQ_0340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EMQ_0341	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EMQ_0343	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EMQ_0345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EMQ_0358	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EMQ_0359	COG1459	type II secretion system
EMQ_0361	COG2165	general secretion pathway protein
EMQ_0367	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EMQ_0369	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMQ_0370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EMQ_0371	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EMQ_0376	COG1289	transmembrane transporter activity
EMQ_0377	COG1566	PFAM secretion protein HlyD family protein
EMQ_0379	COG0539	negative regulation of cytoplasmic translation
EMQ_0381	COG0463	Glycosyl transferase, family 2
EMQ_0383	COG0019	diaminopimelate decarboxylase activity
EMQ_0387	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EMQ_0390	COG1584	GPR1 FUN34 yaaH family protein
EMQ_0392	COG1132	(ABC) transporter
EMQ_0395	COG0432	Pfam Uncharacterised protein family UPF0047
EMQ_0404	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EMQ_0407	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EMQ_0411	COG0356	it plays a direct role in the translocation of protons across the membrane
EMQ_0412	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMQ_0413	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EMQ_0414	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EMQ_0415	COG0463	Glycosyl transferase, family 2
EMQ_0417	COG3293	Transposase
EMQ_0419	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EMQ_0419	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EMQ_0420	COG1494	fructose-1,6-bisphosphatase
EMQ_0422	COG0436	Aminotransferase
EMQ_0424	COG2271	Major facilitator Superfamily
EMQ_0429	COG0390	transport system, permease component
EMQ_0430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EMQ_0434	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EMQ_0435	COG0237	dephospho-CoA kinase activity
EMQ_0441	COG0321	lipoyl(octanoyl) transferase activity
EMQ_0445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EMQ_0451	COG1573	uracil-dna glycosylase
EMQ_0456	COG0175	sulfate reduction
EMQ_0457	COG0175	sulfate reduction
EMQ_0459	COG2226	methyltransferase
EMQ_0461	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EMQ_0468	COG0745	RESPONSE REGULATOR receiver
EMQ_0473	COG0457	Tetratricopeptide repeat
EMQ_0473	COG0859	PFAM glycosyl transferase family 9
EMQ_0474	COG0659	secondary active sulfate transmembrane transporter activity
EMQ_0478	COG1121	(ABC) transporter
EMQ_0481	COG0534	Mate efflux family protein
EMQ_0484	COG1706	bacterial-type flagellum-dependent cell motility
EMQ_0488	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EMQ_0494	COG2999	glutathione oxidoreductase activity
EMQ_0495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EMQ_0496	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EMQ_0497	COG1127	ABC transporter
EMQ_0498	COG3008	intermembrane lipid transfer
EMQ_0498	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EMQ_0501	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EMQ_0503	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EMQ_0504	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EMQ_0505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EMQ_0507	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EMQ_0509	COG0793	Belongs to the peptidase S41A family
EMQ_0511	COG1051	belongs to the nudix hydrolase family
EMQ_0517	COG0489	protein tyrosine kinase activity
EMQ_0517	COG3206	protein involved in exopolysaccharide biosynthesis
EMQ_0522	COG0045	succinate-CoA ligase (ADP-forming) activity
EMQ_0523	COG0604	alcohol dehydrogenase
EMQ_0523	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_0523	COG3321	synthase
EMQ_0524	COG0596	Alpha beta hydrolase
EMQ_0526	COG2719	SpoVR family
EMQ_0527	COG2718	Belongs to the UPF0229 family
EMQ_0528	COG2766	serine protein kinase
EMQ_0530	COG0084	hydrolase, TatD family'
EMQ_0531	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EMQ_0533	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EMQ_0534	COG1686	Belongs to the peptidase S11 family
EMQ_0535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EMQ_0536	COG2951	lytic endotransglycosylase activity
EMQ_0538	COG0586	Pfam SNARE associated Golgi protein
EMQ_0541	COG1968	undecaprenyl-diphosphatase activity
EMQ_0542	COG0531	amino acid
EMQ_0545	COG0165	Argininosuccinate lyase
EMQ_0546	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EMQ_0547	COG3585	molybdate ion transport
EMQ_0548	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EMQ_0549	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EMQ_0552	COG1113	amino acid transport
EMQ_0553	COG1396	sequence-specific DNA binding
EMQ_0553	COG3800	Transcriptional regulator
EMQ_0554	COG2224	Isocitrate lyase
EMQ_0557	COG1346	cytolysis
EMQ_0559	COG1970	mechanosensitive ion channel activity
EMQ_0560	COG0254	rRNA binding
EMQ_0565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EMQ_0568	COG0494	nUDIX hydrolase
EMQ_0569	COG2814	Major facilitator Superfamily
EMQ_0570	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EMQ_0571	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EMQ_0572	COG3293	Transposase
EMQ_0585	COG0271	Belongs to the BolA IbaG family
EMQ_0586	COG0484	heat shock protein binding
EMQ_0589	COG0076	glutamate decarboxylase activity
EMQ_0590	COG0596	Alpha beta hydrolase
EMQ_0592	COG2308	Evidence 4 Homologs of previously reported genes of
EMQ_0594	COG2003	Belongs to the UPF0758 family
EMQ_0595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EMQ_0597	COG0546	phosphoglycolate phosphatase activity
EMQ_0603	COG0697	spore germination
EMQ_0604	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EMQ_0605	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EMQ_0606	COG0546	phosphoglycolate phosphatase activity
EMQ_0607	COG2814	Major facilitator Superfamily
EMQ_0610	COG1692	metallophosphoesterase
EMQ_0611	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EMQ_0615	COG0352	thiamine-phosphate diphosphorylase activity
EMQ_0616	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EMQ_0621	COG2308	Evidence 4 Homologs of previously reported genes of
EMQ_0621	COG2307	Protein conserved in bacteria
EMQ_0627	COG4993	Dehydrogenase
EMQ_0628	COG4993	Dehydrogenase
EMQ_0631	COG0728	peptidoglycan biosynthetic process
EMQ_0636	COG1862	Preprotein translocase
EMQ_0639	COG0494	nUDIX hydrolase
EMQ_0640	COG1546	Belongs to the CinA family
EMQ_0640	COG1058	Belongs to the CinA family
EMQ_0641	COG0825	malonyl-CoA metabolic process
EMQ_0642	COG4974	Belongs to the 'phage' integrase family
EMQ_0644	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EMQ_0645	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EMQ_0645	COG2885	chlorophyll binding
EMQ_0647	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EMQ_0653	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EMQ_0654	COG1196	nuclear chromosome segregation
EMQ_0656	COG0459	protein refolding
EMQ_0657	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EMQ_0658	COG0583	DNA-binding transcription factor activity
EMQ_0663	COG2814	Major facilitator Superfamily
EMQ_0664	COG1045	serine acetyltransferase
EMQ_0667	COG0037	tRNA processing
EMQ_0669	COG2885	chlorophyll binding
EMQ_0670	COG0823	Involved in the tonB-independent uptake of proteins
EMQ_0672	COG0848	biopolymer transport protein
EMQ_0674	COG0824	Thioesterase
EMQ_0675	COG2255	four-way junction helicase activity
EMQ_0676	COG0632	four-way junction helicase activity
EMQ_0677	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EMQ_0680	COG1607	acyl-coa hydrolase
EMQ_0682	COG1929	Belongs to the glycerate kinase type-1 family
EMQ_0684	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EMQ_0685	COG1605	Chorismate mutase
EMQ_0685	COG0287	Prephenate dehydrogenase
EMQ_0686	COG2062	phosphohistidine phosphatase, SixA
EMQ_0695	COG1450	Type ii and iii secretion system protein
EMQ_0698	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EMQ_0699	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EMQ_0700	COG0142	geranyltranstransferase activity
EMQ_0703	COG0783	Belongs to the Dps family
EMQ_0705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EMQ_0707	COG0583	DNA-binding transcription factor activity
EMQ_0708	COG0450	alkyl hydroperoxide reductase
EMQ_0709	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EMQ_0711	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EMQ_0712	COG1923	regulation of RNA biosynthetic process
EMQ_0713	COG2204	response regulator
EMQ_0721	COG0717	Belongs to the dCTP deaminase family
EMQ_0722	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EMQ_0730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMQ_0732	COG1215	transferase activity, transferring glycosyl groups
EMQ_0735	COG2967	ApaG domain
EMQ_0736	COG0302	gtp cyclohydrolase
EMQ_0738	COG0187	DNA topoisomerase II activity
EMQ_0741	COG1959	2 iron, 2 sulfur cluster binding
EMQ_0742	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EMQ_0743	COG2885	chlorophyll binding
EMQ_0743	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EMQ_0745	COG0793	Belongs to the peptidase S41A family
EMQ_0746	COG0557	exoribonuclease II activity
EMQ_0747	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EMQ_0748	COG0758	DNA mediated transformation
EMQ_0749	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EMQ_0750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EMQ_0751	COG0540	Belongs to the ATCase OTCase family
EMQ_0752	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EMQ_0753	COG1289	transmembrane transporter activity
EMQ_0761	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EMQ_0762	COG1674	ftsk spoiiie
EMQ_0763	COG0564	pseudouridine synthase activity
EMQ_0767	COG2022	thiamine diphosphate biosynthetic process
EMQ_0774	COG3800	Transcriptional regulator
EMQ_0774	COG1396	sequence-specific DNA binding
EMQ_0775	COG2079	MmgE PrpD family protein
EMQ_0776	COG0372	Belongs to the citrate synthase family
EMQ_0777	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EMQ_0778	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EMQ_0782	COG1519	Transferase
EMQ_0783	COG1663	tetraacyldisaccharide 4'-kinase activity
EMQ_0786	COG4774	siderophore transport
EMQ_0788	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EMQ_0789	COG0840	transmembrane signaling receptor activity
EMQ_0790	COG0114	fumarate hydratase activity
EMQ_0792	COG4993	Dehydrogenase
EMQ_0795	COG2814	Major facilitator Superfamily
EMQ_0797	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EMQ_0798	COG0564	pseudouridine synthase activity
EMQ_0804	COG0513	Belongs to the DEAD box helicase family
EMQ_0809	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EMQ_0810	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EMQ_0811	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EMQ_0813	COG0024	Methionine aminopeptidase
EMQ_0815	COG0137	argininosuccinate synthase activity
EMQ_0816	COG0545	Peptidyl-prolyl cis-trans isomerase
EMQ_0819	COG0180	Tryptophanyl-tRNA synthetase
EMQ_0821	COG0668	transmembrane transport
EMQ_0822	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EMQ_0823	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EMQ_0829	COG2201	protein-glutamate methylesterase activity
EMQ_0830	COG0248	Ppx GppA phosphatase
EMQ_0832	COG0829	nickel cation binding
EMQ_0833	COG0831	urea catabolic process
EMQ_0834	COG0832	Belongs to the urease beta subunit family
EMQ_0835	COG0804	urea catabolic process
EMQ_0836	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EMQ_0837	COG0830	nickel cation binding
EMQ_0838	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EMQ_0841	COG0583	DNA-binding transcription factor activity
EMQ_0845	COG0411	ABC transporter
EMQ_0850	COG0745	RESPONSE REGULATOR receiver
EMQ_0852	COG4974	Belongs to the 'phage' integrase family
EMQ_0855	COG1902	pentaerythritol trinitrate reductase activity
EMQ_0858	COG0604	alcohol dehydrogenase
EMQ_0859	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EMQ_0860	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EMQ_0861	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EMQ_0862	COG0259	pyridoxamine-phosphate oxidase activity
EMQ_0864	COG2814	Major facilitator Superfamily
EMQ_0865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EMQ_0868	COG0583	DNA-binding transcription factor activity
EMQ_0869	COG3384	dioxygenase
EMQ_0870	COG2353	YceI-like domain
EMQ_0872	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EMQ_0874	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_0878	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EMQ_0879	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EMQ_0880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EMQ_0881	COG3300	MHYT domain
EMQ_0881	COG5001	Diguanylate cyclase
EMQ_0883	COG0556	nucleotide-excision repair
EMQ_0884	COG1530	ribonuclease E activity
EMQ_0892	COG3706	GGDEF domain
EMQ_0893	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EMQ_0894	COG0124	histidyl-tRNA synthetase
EMQ_0895	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EMQ_0897	COG2070	2-Nitropropane dioxygenase
EMQ_0898	COG0527	aspartate kinase activity
EMQ_0899	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EMQ_0900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EMQ_0901	COG0359	binds to the 23S rRNA
EMQ_0902	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EMQ_0903	COG0360	Binds together with S18 to 16S ribosomal RNA
EMQ_0905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EMQ_0906	COG0358	DNA primase activity
EMQ_0907	COG1610	YqeY-like protein
EMQ_0909	COG0010	Belongs to the arginase family
EMQ_0912	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_0915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EMQ_0917	COG0505	Belongs to the CarA family
EMQ_0919	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EMQ_0920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EMQ_0921	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EMQ_0923	COG0799	negative regulation of ribosome biogenesis
EMQ_0924	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EMQ_0925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EMQ_0926	COG0012	GTP binding
EMQ_0927	COG0193	aminoacyl-tRNA hydrolase activity
EMQ_0928	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EMQ_0934	COG0768	penicillin binding
EMQ_0935	COG0772	Belongs to the SEDS family
EMQ_0937	COG0484	heat shock protein binding
EMQ_0939	COG0025	NhaP-type Na H and K H
EMQ_0941	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EMQ_0942	COG0277	FAD linked oxidase domain protein
EMQ_0943	COG0778	Nitroreductase
EMQ_0944	COG2244	polysaccharide biosynthetic process
EMQ_0945	COG0481	GTPase activity
EMQ_0947	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EMQ_0949	COG5001	Diguanylate cyclase
EMQ_0950	COG0431	NADPH-dependent FMN reductase
EMQ_0951	COG0513	Belongs to the DEAD box helicase family
EMQ_0953	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EMQ_0954	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EMQ_0955	COG0552	protein localization to endoplasmic reticulum
EMQ_0967	COG0667	Aldo Keto reductase
EMQ_0968	COG1054	Belongs to the UPF0176 family
EMQ_0974	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EMQ_0975	COG3158	transport of potassium into the cell
EMQ_0976	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EMQ_0980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EMQ_0981	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EMQ_0982	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EMQ_0983	COG0424	maF-like protein
EMQ_0985	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EMQ_0986	COG0315	cyclic pyranopterin monophosphate synthase activity
EMQ_0989	COG0723	plastoquinol--plastocyanin reductase activity
EMQ_0991	COG0477	Major facilitator Superfamily
EMQ_0994	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EMQ_0994	COG2010	Cytochrome c
EMQ_0995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EMQ_1000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EMQ_1004	COG0113	porphobilinogen synthase activity
EMQ_1006	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EMQ_1008	COG2205	protein histidine kinase activity
EMQ_1017	COG3293	Transposase
EMQ_1024	COG0521	Mo-molybdopterin cofactor biosynthetic process
EMQ_1026	COG1295	ribonuclease BN
EMQ_1028	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EMQ_1029	COG0511	ligase activity, forming carbon-carbon bonds
EMQ_1030	COG0439	Biotin carboxylase
EMQ_1031	COG0138	bifunctional purine biosynthesis protein purh
EMQ_1033	COG3541	Predicted nucleotidyltransferase
EMQ_1034	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EMQ_1035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EMQ_1036	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EMQ_1037	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMQ_1039	COG0792	nuclease activity
EMQ_1041	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EMQ_1042	COG0271	Belongs to the BolA IbaG family
EMQ_1043	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMQ_1044	COG0047	phosphoribosylformylglycinamidine synthase activity
EMQ_1046	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMQ_1047	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EMQ_1048	COG0110	maltose O-acetyltransferase activity
EMQ_1049	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EMQ_1050	COG4774	siderophore transport
EMQ_1051	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EMQ_1053	COG0657	acetylesterase activity
EMQ_1054	COG2001	Belongs to the MraZ family
EMQ_1055	COG0275	rRNA processing
EMQ_1058	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EMQ_1059	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EMQ_1060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EMQ_1061	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EMQ_1063	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EMQ_1064	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EMQ_1065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EMQ_1066	COG1181	Belongs to the D-alanine--D-alanine ligase family
EMQ_1067	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EMQ_1068	COG0849	cell division
EMQ_1071	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EMQ_1072	COG0497	DNA recombination
EMQ_1073	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EMQ_1074	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EMQ_1074	COG0574	Belongs to the PEP-utilizing enzyme family
EMQ_1075	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EMQ_1078	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EMQ_1083	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EMQ_1085	COG3145	DNA-N1-methyladenine dioxygenase activity
EMQ_1089	COG0242	peptide deformylase activity
EMQ_1090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EMQ_1091	COG0101	tRNA pseudouridine synthase activity
EMQ_1098	COG2814	Major facilitator Superfamily
EMQ_1099	COG2837	iron assimilation
EMQ_1102	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EMQ_1104	COG5441	Belongs to the UPF0261 family
EMQ_1105	COG5564	TIM-barrel signal transduction protein
EMQ_1107	COG0778	Nitroreductase
EMQ_1108	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EMQ_1112	COG0667	Aldo Keto reductase
EMQ_1118	COG3645	SOS response
EMQ_1125	COG0438	transferase activity, transferring glycosyl groups
EMQ_1126	COG1215	transferase activity, transferring glycosyl groups
EMQ_1128	COG2003	Belongs to the UPF0758 family
EMQ_1129	COG2814	Major facilitator Superfamily
EMQ_1130	COG1566	PFAM secretion protein HlyD family protein
EMQ_1135	COG1987	bacterial-type flagellum assembly
EMQ_1136	COG1677	Flagellar hook-basal body complex protein FliE
EMQ_1137	COG1558	bacterial-type flagellum-dependent cell motility
EMQ_1138	COG1815	bacterial-type flagellum-dependent cell motility
EMQ_1140	COG1338	Plays a role in the flagellum-specific transport system
EMQ_1141	COG1136	(ABC) transporter
EMQ_1143	COG0442	prolyl-tRNA aminoacylation
EMQ_1146	COG0493	'glutamate synthase
EMQ_1150	COG1953	Uracil, thiamine, allantoin
EMQ_1153	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EMQ_1155	COG1007	ATP synthesis coupled electron transport
EMQ_1159	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_1160	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EMQ_1161	COG1034	ATP synthesis coupled electron transport
EMQ_1163	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EMQ_1164	COG0649	NAD binding
EMQ_1165	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_1166	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_1167	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_1168	COG0776	regulation of translation
EMQ_1170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EMQ_1171	COG0740	serine-type endopeptidase activity
EMQ_1172	COG0544	peptidyl-prolyl cis-trans isomerase activity
EMQ_1173	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EMQ_1173	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EMQ_1175	COG0513	Belongs to the DEAD box helicase family
EMQ_1182	COG2814	Major facilitator Superfamily
EMQ_1188	COG5001	Diguanylate cyclase
EMQ_1188	COG3300	MHYT domain
EMQ_1189	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EMQ_1191	COG3265	gluconokinase activity
EMQ_1192	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EMQ_1193	COG0363	glucosamine-6-phosphate deaminase activity
EMQ_1194	COG0561	phosphatase activity
EMQ_1195	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EMQ_1196	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EMQ_1199	COG1570	exodeoxyribonuclease VII activity
EMQ_1201	COG0179	Fumarylacetoacetate (FAA) hydrolase
EMQ_1202	COG1216	Glycosyl transferase, family 2
EMQ_1202	COG0438	transferase activity, transferring glycosyl groups
EMQ_1204	COG1657	PFAM Prenyltransferase squalene oxidase
EMQ_1205	COG1233	COG1233 Phytoene dehydrogenase and related
EMQ_1206	COG1562	ergosterol biosynthetic process
EMQ_1207	COG1562	ergosterol biosynthetic process
EMQ_1208	COG1051	belongs to the nudix hydrolase family
EMQ_1210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EMQ_1212	COG0287	Prephenate dehydrogenase
EMQ_1215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMQ_1217	COG0109	protoheme IX farnesyltransferase activity
EMQ_1219	COG2226	methyltransferase
EMQ_1220	COG0189	ligase activity
EMQ_1222	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EMQ_1223	COG1360	Flagellar Motor Protein
EMQ_1226	COG1522	sequence-specific DNA binding
EMQ_1227	COG0492	ferredoxin-NADP+ reductase activity
EMQ_1228	COG0583	DNA-binding transcription factor activity
EMQ_1229	COG1321	iron dependent repressor
EMQ_1236	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EMQ_1238	COG0616	signal peptide processing
EMQ_1239	COG0776	regulation of translation
EMQ_1241	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EMQ_1241	COG0662	Cupin 2, conserved barrel domain protein
EMQ_1245	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EMQ_1246	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EMQ_1249	COG1607	acyl-coa hydrolase
EMQ_1250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EMQ_1251	COG0354	folic acid binding
EMQ_1252	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EMQ_1253	COG0242	peptide deformylase activity
EMQ_1255	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EMQ_1256	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EMQ_1258	COG1722	exodeoxyribonuclease VII activity
EMQ_1262	COG1940	carbohydrate kinase activity
EMQ_1263	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EMQ_1264	COG0316	Belongs to the HesB IscA family
EMQ_1265	COG2151	metal-sulfur cluster biosynthetic enzyme
EMQ_1267	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EMQ_1268	COG0719	Fe-S assembly protein
EMQ_1269	COG0396	ATPase activity
EMQ_1270	COG0719	Fe-S assembly protein
EMQ_1271	COG1959	2 iron, 2 sulfur cluster binding
EMQ_1273	COG2733	membrane
EMQ_1277	COG0156	8-amino-7-oxononanoate synthase activity
EMQ_1281	COG0126	phosphoglycerate kinase activity
EMQ_1287	COG2205	protein histidine kinase activity
EMQ_1293	COG2223	nitrite transmembrane transporter activity
EMQ_1295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EMQ_1295	COG2146	nitrite reductase [NAD(P)H] activity
EMQ_1296	COG0243	molybdopterin cofactor binding
EMQ_1298	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EMQ_1298	COG1116	anion transmembrane transporter activity
EMQ_1301	COG0803	Belongs to the bacterial solute-binding protein 9 family
EMQ_1306	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EMQ_1307	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EMQ_1309	COG5265	(ABC) transporter
EMQ_1313	COG2226	methyltransferase
EMQ_1313	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EMQ_1313	COG0596	Alpha beta hydrolase
EMQ_1319	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EMQ_1319	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EMQ_1321	COG0737	Belongs to the 5'-nucleotidase family
EMQ_1322	COG3572	ergothioneine biosynthetic process
EMQ_1324	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EMQ_1326	COG0513	Belongs to the DEAD box helicase family
EMQ_1327	COG4106	trans-aconitate 2-methyltransferase activity
EMQ_1327	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EMQ_1329	COG0156	8-amino-7-oxononanoate synthase activity
EMQ_1330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EMQ_1331	COG0314	molybdopterin synthase activity
EMQ_1332	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EMQ_1334	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EMQ_1335	COG0322	excinuclease ABC activity
EMQ_1339	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EMQ_1341	COG0745	RESPONSE REGULATOR receiver
EMQ_1346	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EMQ_1347	COG0438	transferase activity, transferring glycosyl groups
EMQ_1347	COG1216	Glycosyl transferase, family 2
EMQ_1350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EMQ_1355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EMQ_1356	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EMQ_1357	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EMQ_1358	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EMQ_1359	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EMQ_1360	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EMQ_1361	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMQ_1363	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EMQ_1366	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EMQ_1368	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EMQ_1369	COG1053	succinate dehydrogenase
EMQ_1370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EMQ_1373	COG2824	Alkylphosphonate utilization operon protein PhnA
EMQ_1375	COG3920	Histidine kinase
EMQ_1375	COG2202	Pas domain
EMQ_1377	COG0488	(ABC) transporter
EMQ_1379	COG0628	permease
EMQ_1384	COG0006	proline dipeptidase activity
EMQ_1385	COG0473	3-isopropylmalate dehydrogenase activity
EMQ_1404	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EMQ_1405	COG0072	phenylalanine-tRNA ligase activity
EMQ_1405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EMQ_1406	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EMQ_1407	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EMQ_1412	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EMQ_1413	COG2203	Gaf domain
EMQ_1413	COG3706	GGDEF domain
EMQ_1413	COG4251	negative regulation of phosphorylation
EMQ_1413	COG5001	Diguanylate cyclase
EMQ_1417	COG0612	Peptidase, M16
EMQ_1418	COG0312	modulator of DNA gyrase
EMQ_1420	COG2755	lipolytic protein G-D-S-L family
EMQ_1420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EMQ_1421	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EMQ_1422	COG1454	alcohol dehydrogenase
EMQ_1423	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EMQ_1423	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EMQ_1424	COG0194	GDP metabolic process
EMQ_1425	COG0300	oxidoreductase activity
EMQ_1426	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EMQ_1428	COG0582	viral genome integration into host DNA
EMQ_1435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EMQ_1437	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EMQ_1439	COG0583	DNA-binding transcription factor activity
EMQ_1440	COG2146	nitrite reductase [NAD(P)H] activity
EMQ_1440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EMQ_1441	COG0604	alcohol dehydrogenase
EMQ_1449	COG2814	Major facilitator Superfamily
EMQ_1450	COG2132	Multicopper oxidase
EMQ_1468	COG1116	anion transmembrane transporter activity
EMQ_1469	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EMQ_1469	COG1116	anion transmembrane transporter activity
EMQ_1470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EMQ_1472	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EMQ_1474	COG0583	DNA-binding transcription factor activity
EMQ_1475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EMQ_1476	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EMQ_1482	COG1116	anion transmembrane transporter activity
EMQ_1488	COG0415	Belongs to the DNA photolyase family
EMQ_1497	COG1566	PFAM secretion protein HlyD family protein
EMQ_1506	COG0586	Pfam SNARE associated Golgi protein
EMQ_1507	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_1508	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EMQ_1510	COG0140	phosphoribosyl-ATP diphosphatase activity
EMQ_1511	COG0107	imidazoleglycerol-phosphate synthase activity
EMQ_1512	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EMQ_1513	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EMQ_1515	COG0131	Imidazoleglycerol-phosphate dehydratase
EMQ_1516	COG5001	Diguanylate cyclase
EMQ_1516	COG3300	MHYT domain
EMQ_1520	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EMQ_1526	COG1199	ATP-dependent helicase activity
EMQ_1535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EMQ_1538	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMQ_1543	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EMQ_1544	COG0531	amino acid
EMQ_1545	COG1253	flavin adenine dinucleotide binding
EMQ_1546	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EMQ_1547	COG1671	Belongs to the UPF0178 family
EMQ_1548	COG0438	transferase activity, transferring glycosyl groups
EMQ_1550	COG1597	lipid kinase activity
EMQ_1552	COG2326	polyphosphate kinase activity
EMQ_1553	COG4221	oxidoreductase activity
EMQ_1554	COG1678	Uncharacterized ACR, COG1678
EMQ_1560	COG1217	gtp-binding protein TYPA
EMQ_1565	COG2818	Glycosylase
EMQ_1566	COG0473	3-isopropylmalate dehydrogenase activity
EMQ_1569	COG1289	transmembrane transporter activity
EMQ_1570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EMQ_1572	COG2814	Major facilitator Superfamily
EMQ_1575	COG1612	heme a metabolic process
EMQ_1586	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EMQ_1590	COG0489	protein tyrosine kinase activity
EMQ_1593	COG0741	lytic transglycosylase activity
EMQ_1594	COG1573	uracil-dna glycosylase
EMQ_1598	COG1215	transferase activity, transferring glycosyl groups
EMQ_1605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EMQ_1606	COG0066	3-isopropylmalate dehydratase activity
EMQ_1608	COG0778	Nitroreductase
EMQ_1609	COG3042	response to heat
EMQ_1611	COG0581	inorganic phosphate transmembrane transporter activity
EMQ_1612	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EMQ_1614	COG0745	RESPONSE REGULATOR receiver
EMQ_1616	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EMQ_1618	COG0335	large ribosomal subunit rRNA binding
EMQ_1619	COG0336	Belongs to the RNA methyltransferase TrmD family
EMQ_1620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EMQ_1621	COG0228	four-way junction DNA binding
EMQ_1627	COG0316	Belongs to the HesB IscA family
EMQ_1629	COG0347	Belongs to the P(II) protein family
EMQ_1630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EMQ_1632	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EMQ_1635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EMQ_1636	COG1942	4-Oxalocrotonate Tautomerase
EMQ_1638	COG4303	Ethanolamine ammonia lyase large subunit
EMQ_1639	COG4302	ethanolamine ammonia-lyase activity
EMQ_1640	COG0531	amino acid
EMQ_1642	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EMQ_1644	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EMQ_1646	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EMQ_1651	COG3660	Nucleoside-diphosphate-sugar epimerase
EMQ_1652	COG0148	phosphopyruvate hydratase activity
EMQ_1654	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EMQ_1655	COG0303	'Molybdopterin
EMQ_1658	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EMQ_1659	COG0285	dihydrofolate synthase activity
EMQ_1662	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EMQ_1664	COG1177	transmembrane transport
EMQ_1665	COG1176	ABC-type spermidine putrescine transport system, permease component I
EMQ_1666	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EMQ_1674	COG0848	biopolymer transport protein
EMQ_1677	COG4774	siderophore transport
EMQ_1678	COG3128	pkhd-type hydroxylase
EMQ_1680	COG0167	dihydroorotate dehydrogenase activity
EMQ_1681	COG5487	UPF0391 membrane protein
EMQ_1683	COG1116	anion transmembrane transporter activity
EMQ_1686	COG0203	ribosomal protein L17
EMQ_1687	COG0202	RNA polymerase activity
EMQ_1688	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EMQ_1689	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EMQ_1690	COG0563	adenylate kinase activity
EMQ_1691	COG0201	protein transport
EMQ_1692	COG0200	Binds to the 23S rRNA
EMQ_1693	COG1841	ribosomal large subunit assembly
EMQ_1694	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EMQ_1695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EMQ_1696	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EMQ_1697	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EMQ_1698	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EMQ_1699	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EMQ_1700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EMQ_1701	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EMQ_1702	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EMQ_1703	COG0255	Belongs to the universal ribosomal protein uL29 family
EMQ_1704	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EMQ_1705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EMQ_1706	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EMQ_1707	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EMQ_1708	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EMQ_1709	COG0089	rRNA binding
EMQ_1710	COG0088	Forms part of the polypeptide exit tunnel
EMQ_1711	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EMQ_1712	COG0051	transcription antitermination factor activity, RNA binding
EMQ_1713	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EMQ_1714	COG0049	tRNA binding
EMQ_1715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EMQ_1717	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMQ_1718	COG0085	RNA polymerase activity
EMQ_1719	COG0222	ribosome binding
EMQ_1720	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EMQ_1721	COG0081	regulation of translation
EMQ_1722	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EMQ_1725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EMQ_1726	COG0235	Class ii aldolase
EMQ_1727	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EMQ_1728	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EMQ_1729	COG0196	riboflavin kinase activity
EMQ_1731	COG4716	Myosin-crossreactive antigen
EMQ_1741	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EMQ_1742	COG2943	transferase activity, transferring hexosyl groups
EMQ_1745	COG0658	competence protein
EMQ_1745	COG2333	competence protein COMEC
EMQ_1749	COG0483	inositol monophosphate 1-phosphatase activity
EMQ_1750	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EMQ_1753	COG0776	regulation of translation
EMQ_1754	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EMQ_1755	COG0416	fatty acid biosynthetic process
EMQ_1756	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EMQ_1760	COG0745	RESPONSE REGULATOR receiver
EMQ_1763	COG0242	peptide deformylase activity
EMQ_1765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EMQ_1775	COG0646	methionine synthase
EMQ_1775	COG1410	methionine synthase
EMQ_1776	COG2132	Multicopper oxidase
EMQ_1778	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EMQ_1779	COG0492	ferredoxin-NADP+ reductase activity
EMQ_1780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EMQ_1781	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EMQ_1782	COG2814	Major facilitator Superfamily
EMQ_1785	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EMQ_1787	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EMQ_1789	COG0598	Magnesium transport protein CorA
EMQ_1791	COG1091	dTDP-4-dehydrorhamnose reductase activity
EMQ_1793	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EMQ_1799	COG0587	DNA-directed DNA polymerase activity
EMQ_1808	COG2217	Heavy metal translocating P-type atpase
EMQ_1809	COG1937	Protein conserved in bacteria
EMQ_1810	COG2132	Multicopper oxidase
EMQ_1814	COG1017	nitric oxide dioxygenase activity
EMQ_1814	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EMQ_1815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EMQ_1831	COG5489	Protein of unknown function (DUF736)
EMQ_1839	COG1192	Involved in chromosome partitioning
EMQ_1845	COG0741	lytic transglycosylase activity
EMQ_1850	COG0431	NADPH-dependent FMN reductase
EMQ_1851	COG2072	flavoprotein involved in K transport
EMQ_1864	COG0789	Transcriptional regulator
EMQ_1867	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EMQ_1868	COG0789	Transcriptional regulator
EMQ_1876	COG4962	Type ii secretion system protein e
EMQ_1879	COG3451	type IV secretory pathway VirB4
EMQ_1886	COG0583	DNA-binding transcription factor activity
EMQ_1889	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EMQ_1890	COG0583	DNA-binding transcription factor activity
EMQ_1891	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_1894	COG0523	cobalamin synthesis protein
EMQ_1897	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EMQ_1899	COG2814	Major facilitator Superfamily
EMQ_1901	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EMQ_1903	COG2897	thiosulfate sulfurtransferase activity
EMQ_1905	COG0628	permease
EMQ_1908	COG3047	cAMP biosynthetic process
EMQ_1909	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EMQ_1911	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EMQ_1913	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EMQ_1914	COG3293	Transposase
EMQ_1918	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EMQ_1920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EMQ_1921	COG2113	Glycine betaine
EMQ_1922	COG4175	Glycine betaine
EMQ_1922	COG3448	diguanylate cyclase activity
EMQ_1923	COG4176	ABC-type proline glycine betaine transport system permease component
EMQ_1927	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EMQ_1930	COG0446	pyridine nucleotide-disulphide oxidoreductase
EMQ_1930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EMQ_1931	COG4311	Sarcosine oxidase, delta subunit
EMQ_1932	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EMQ_1935	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EMQ_1936	COG2218	PFAM glutamate synthase alpha subunit domain protein
EMQ_1937	COG0069	glutamate synthase activity
EMQ_1940	COG0004	ammonium transporteR
EMQ_1941	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EMQ_1945	COG0284	orotidine-5'-phosphate decarboxylase activity
EMQ_1952	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EMQ_1953	COG0602	queuosine metabolic process
EMQ_1954	COG1742	UPF0060 membrane protein
EMQ_1957	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EMQ_1962	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EMQ_1963	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EMQ_1964	COG0583	DNA-binding transcription factor activity
EMQ_1966	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EMQ_1967	COG0129	dihydroxy-acid dehydratase activity
EMQ_1969	COG2070	2-Nitropropane dioxygenase
EMQ_1970	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EMQ_1975	COG3128	pkhd-type hydroxylase
EMQ_1978	COG1959	2 iron, 2 sulfur cluster binding
EMQ_1982	COG0513	Belongs to the DEAD box helicase family
EMQ_1984	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EMQ_1984	COG2813	Specifically methylates the guanine in position
EMQ_1985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EMQ_1987	COG3088	subunit of a heme lyase
EMQ_1988	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EMQ_1989	COG1138	Cytochrome C-type biogenesis protein
EMQ_1990	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EMQ_1992	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EMQ_1998	COG4993	Dehydrogenase
EMQ_2000	COG0402	S-adenosylhomocysteine deaminase activity
EMQ_2005	COG2375	cellular response to nickel ion
EMQ_2006	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EMQ_2009	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EMQ_2010	COG0408	coproporphyrinogen oxidase activity
EMQ_2012	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EMQ_2013	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EMQ_2015	COG1660	Displays ATPase and GTPase activities
EMQ_2016	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EMQ_2020	COG0297	glycogen (starch) synthase activity
EMQ_2027	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EMQ_2028	COG0805	protein transport
EMQ_2029	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EMQ_2031	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EMQ_2032	COG0022	dehydrogenase e1 component
EMQ_2033	COG0508	dehydrogenase complex catalyzes the overall conversion of
EMQ_2033	COG0596	Alpha beta hydrolase
EMQ_2034	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_2036	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EMQ_2040	COG0343	queuine tRNA-ribosyltransferase activity
EMQ_2041	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EMQ_2043	COG1733	regulation of RNA biosynthetic process
EMQ_2044	COG0702	epimerase
EMQ_2048	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EMQ_2049	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EMQ_2055	COG0484	heat shock protein binding
EMQ_2056	COG0443	Heat shock 70 kDa protein
EMQ_2058	COG0745	RESPONSE REGULATOR receiver
EMQ_2059	COG0642	Histidine kinase
EMQ_2060	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EMQ_2062	COG1643	Atp-dependent helicase
EMQ_2064	COG4232	protein-disulfide reductase activity
EMQ_2069	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EMQ_2070	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EMQ_2071	COG0445	tRNA wobble uridine modification
EMQ_2072	COG0357	Ribosomal RNA small subunit methyltransferase G
EMQ_2083	COG0582	viral genome integration into host DNA
EMQ_2084	COG1396	sequence-specific DNA binding
EMQ_2085	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EMQ_2110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EMQ_2116	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EMQ_2117	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EMQ_2123	COG0784	Response regulator, receiver
EMQ_2123	COG2198	Histidine kinase
EMQ_2123	COG5002	protein histidine kinase activity
EMQ_2125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EMQ_2126	COG1914	H( )-stimulated, divalent metal cation uptake system
EMQ_2127	COG0436	Aminotransferase
EMQ_2129	COG2814	Major facilitator Superfamily
EMQ_2136	COG1981	membrane
EMQ_2137	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EMQ_2138	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EMQ_2139	COG0424	maF-like protein
EMQ_2140	COG1505	serine-type exopeptidase activity
EMQ_2144	COG0482	sulfurtransferase activity
EMQ_2146	COG1104	cysteine desulfurase activity
EMQ_2147	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EMQ_2148	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EMQ_2152	COG1120	ATPase activity
EMQ_2153	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EMQ_2154	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EMQ_2155	COG1959	2 iron, 2 sulfur cluster binding
EMQ_2156	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EMQ_2157	COG0859	PFAM glycosyl transferase family 9
EMQ_2161	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EMQ_2164	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EMQ_2167	COG0431	NADPH-dependent FMN reductase
EMQ_2174	COG1566	PFAM secretion protein HlyD family protein
EMQ_2175	COG2814	Major facilitator Superfamily
EMQ_2178	COG2091	lysine biosynthetic process via aminoadipic acid
EMQ_2180	COG0488	(ABC) transporter
EMQ_2181	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EMQ_2185	COG4993	Dehydrogenase
EMQ_2187	COG1012	belongs to the aldehyde dehydrogenase family
EMQ_2188	COG1012	belongs to the aldehyde dehydrogenase family
EMQ_2189	COG1393	Belongs to the ArsC family
EMQ_2193	COG1294	oxidase, subunit
EMQ_2194	COG1271	oxidase subunit
EMQ_2198	COG1278	Cold shock
EMQ_2200	COG1881	PFAM PEBP family protein
EMQ_2211	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EMQ_2213	COG0246	Mannitol dehydrogenase
EMQ_2214	COG1090	epimerase
EMQ_2219	COG0519	Catalyzes the synthesis of GMP from XMP
EMQ_2219	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EMQ_2220	COG3093	addiction module antidote protein HigA
EMQ_2231	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EMQ_2232	COG0156	8-amino-7-oxononanoate synthase activity
EMQ_2233	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMQ_2234	COG0318	PFAM AMP-dependent synthetase and ligase
EMQ_2248	COG5489	Protein of unknown function (DUF736)
EMQ_2249	COG1476	TRANSCRIPTIONal
EMQ_2257	COG0741	lytic transglycosylase activity
EMQ_2259	COG2267	carboxylic ester hydrolase activity
EMQ_2275	COG0450	alkyl hydroperoxide reductase
EMQ_2277	COG4988	ABC transporter
EMQ_2278	COG1132	(ABC) transporter
EMQ_2279	COG1271	oxidase subunit
EMQ_2280	COG1294	oxidase, subunit
EMQ_2285	COG3290	protein histidine kinase activity
EMQ_2287	COG1595	DNA-templated transcription, initiation
EMQ_2301	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EMQ_2306	COG1116	anion transmembrane transporter activity
EMQ_2307	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EMQ_2308	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EMQ_2309	COG1960	acyl-CoA dehydrogenase activity
EMQ_2313	COG0753	catalase activity
EMQ_2314	COG1012	belongs to the aldehyde dehydrogenase family
EMQ_2318	COG1194	a g-specific adenine glycosylase
EMQ_2320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EMQ_2327	COG1797	cobyrinic acid a,c-diamide synthase activity
EMQ_2329	COG1492	cobalamin metabolic process
EMQ_2332	COG1289	transmembrane transporter activity
EMQ_2335	COG0305	Participates in initiation and elongation during chromosome replication
EMQ_2339	COG0009	L-threonylcarbamoyladenylate synthase
EMQ_2341	COG2814	Major facilitator Superfamily
EMQ_2343	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EMQ_2345	COG0656	L-ascorbic acid biosynthetic process
EMQ_2359	COG0517	IMP dehydrogenase activity
EMQ_2360	COG4974	Belongs to the 'phage' integrase family
EMQ_2368	COG5489	Protein of unknown function (DUF736)
EMQ_2376	COG1192	Involved in chromosome partitioning
EMQ_2382	COG0741	lytic transglycosylase activity
EMQ_2391	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EMQ_2396	COG4962	Type ii secretion system protein e
EMQ_2397	COG3838	Conjugal transfer protein Trbc
EMQ_2399	COG3451	type IV secretory pathway VirB4
EMQ_2402	COG3846	protein secretion by the type IV secretion system
EMQ_2405	COG2948	multi-organism process
EMQ_2407	COG0583	DNA-binding transcription factor activity
EMQ_2408	COG1309	transcriptional regulator
EMQ_2409	COG0667	Aldo Keto reductase
EMQ_2410	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_2412	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_2414	COG2814	Major facilitator Superfamily
EMQ_2420	COG0583	DNA-binding transcription factor activity
EMQ_2421	COG4221	oxidoreductase activity
EMQ_2431	COG0318	PFAM AMP-dependent synthetase and ligase
EMQ_2435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMQ_2437	COG2226	methyltransferase
EMQ_2438	COG1368	sulfuric ester hydrolase activity
EMQ_2441	COG0018	arginyl-trna synthetase
EMQ_2443	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EMQ_2444	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EMQ_2447	COG0495	leucyl-tRNA aminoacylation
EMQ_2452	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMQ_2456	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EMQ_2460	COG0604	alcohol dehydrogenase
EMQ_2461	COG0251	oxidation-reduction process
EMQ_2464	COG2755	lipolytic protein G-D-S-L family
EMQ_2464	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EMQ_2470	COG1012	belongs to the aldehyde dehydrogenase family
EMQ_2472	COG0583	DNA-binding transcription factor activity
EMQ_2475	COG2831	hemolysin activation secretion protein
EMQ_2476	COG3210	domain, Protein
EMQ_2481	COG0564	pseudouridine synthase activity
EMQ_2483	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EMQ_2484	COG0667	Aldo Keto reductase
EMQ_2485	COG1420	regulation of RNA biosynthetic process
EMQ_2492	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EMQ_2495	COG0469	pyruvate kinase activity
EMQ_2496	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EMQ_2497	COG0352	thiamine-phosphate diphosphorylase activity
EMQ_2497	COG0351	phosphomethylpyrimidine kinase
EMQ_2501	COG0802	atpase or kinase
EMQ_2502	COG2887	Belongs to the helicase family. UvrD subfamily
EMQ_2503	COG1074	ATP-dependent DNA helicase activity
EMQ_2507	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EMQ_2508	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EMQ_2510	COG0508	dehydrogenase complex catalyzes the overall conversion of
EMQ_2511	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EMQ_2518	COG2875	Belongs to the precorrin methyltransferase family
EMQ_2521	COG2099	Precorrin-6x reductase
EMQ_2528	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EMQ_2532	COG0560	Phosphoserine phosphatase
EMQ_2532	COG3830	Belongs to the UPF0237 family
EMQ_2533	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EMQ_2534	COG0028	Belongs to the TPP enzyme family
EMQ_2536	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EMQ_2543	COG0436	Aminotransferase
EMQ_2546	COG0511	ligase activity, forming carbon-carbon bonds
EMQ_2547	COG4221	oxidoreductase activity
EMQ_2548	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EMQ_2549	COG1984	allophanate hydrolase subunit 2
EMQ_2550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EMQ_2551	COG0697	spore germination
EMQ_2552	COG2271	Major facilitator Superfamily
EMQ_2559	COG0133	tryptophan synthase activity
EMQ_2560	COG0159	tryptophan synthase activity
EMQ_2564	COG2983	Belongs to the UPF0260 family
EMQ_2573	COG0492	ferredoxin-NADP+ reductase activity
EMQ_2574	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EMQ_2575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EMQ_2577	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EMQ_2577	COG0506	proline dehydrogenase activity
EMQ_2577	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EMQ_2578	COG0655	NAD(P)H dehydrogenase (quinone) activity
EMQ_2579	COG0583	DNA-binding transcription factor activity
EMQ_2582	COG0307	riboflavin synthase, alpha
EMQ_2583	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EMQ_2583	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EMQ_2584	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EMQ_2586	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EMQ_2587	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EMQ_2596	COG1252	NADH dehydrogenase
EMQ_2600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EMQ_2600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EMQ_2601	COG0509	glycine decarboxylation via glycine cleavage system
EMQ_2602	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EMQ_2603	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EMQ_2604	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EMQ_2608	COG0776	regulation of translation
EMQ_2614	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EMQ_2618	COG2096	Adenosyltransferase
EMQ_2623	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EMQ_2625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EMQ_2630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EMQ_2631	COG1758	RNA polymerase activity
EMQ_2632	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EMQ_2633	COG0736	holo-[acyl-carrier-protein] synthase activity
EMQ_2634	COG0681	Belongs to the peptidase S26 family
EMQ_2635	COG0571	ribonuclease III activity
EMQ_2636	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EMQ_2637	COG0528	UMP kinase activity
EMQ_2638	COG0233	cytoplasmic translational termination
EMQ_2639	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EMQ_2640	COG0575	Belongs to the CDS family
EMQ_2641	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EMQ_2642	COG0750	zinc metalloprotease
EMQ_2643	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EMQ_2645	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EMQ_2646	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EMQ_2647	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EMQ_2648	COG3494	Protein of unknown function (DUF1009)
EMQ_2650	COG0346	lactoylglutathione lyase activity
EMQ_2652	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EMQ_2653	COG0594	ribonuclease P activity
EMQ_2654	COG0706	membrane insertase activity
EMQ_2655	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EMQ_2656	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EMQ_2659	COG0670	Belongs to the BI1 family
EMQ_2663	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EMQ_2667	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EMQ_2670	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EMQ_2672	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EMQ_2676	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EMQ_2681	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EMQ_2682	COG1396	sequence-specific DNA binding
EMQ_2684	COG0629	single-stranded DNA binding
EMQ_2685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EMQ_2685	COG2010	Cytochrome c
EMQ_2688	COG0326	Molecular chaperone. Has ATPase activity
EMQ_2690	COG0488	(ABC) transporter
EMQ_2691	COG0784	Response regulator, receiver
EMQ_2700	COG1902	pentaerythritol trinitrate reductase activity
EMQ_2700	COG0446	pyridine nucleotide-disulphide oxidoreductase
EMQ_2710	COG5489	Protein of unknown function (DUF736)
EMQ_2712	COG1476	TRANSCRIPTIONal
EMQ_2733	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMQ_2738	COG1271	oxidase subunit
EMQ_2739	COG1294	oxidase, subunit
EMQ_2741	COG0243	molybdopterin cofactor binding
EMQ_2743	COG0315	cyclic pyranopterin monophosphate synthase activity
EMQ_2743	COG0746	molybdenum cofactor guanylyltransferase activity
EMQ_2745	COG0314	molybdopterin synthase activity
EMQ_2746	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EMQ_2749	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EMQ_2751	COG4786	Flagellar basal body rod
EMQ_2752	COG4786	Flagellar basal body rod
EMQ_2754	COG0778	Nitroreductase
EMQ_2759	COG0477	Major facilitator Superfamily
EMQ_2763	COG1322	Protein conserved in bacteria
EMQ_2764	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMQ_2770	COG1877	trehalose-phosphatase activity
EMQ_2771	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EMQ_2772	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EMQ_2775	COG0542	response to heat
EMQ_2777	COG3038	cytochrome b561
EMQ_2781	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EMQ_2785	COG2072	flavoprotein involved in K transport
EMQ_2805	COG2932	Transcriptional regulator
EMQ_2807	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EMQ_2808	COG1116	anion transmembrane transporter activity
EMQ_2809	COG0864	Transcriptional regulator
EMQ_2811	COG3665	Urea carboxylase-associated protein
EMQ_2815	COG2072	flavoprotein involved in K transport
EMQ_2818	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EMQ_2820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EMQ_2822	COG0583	DNA-binding transcription factor activity
EMQ_2823	COG1126	abc transporter atp-binding protein
EMQ_2833	COG0538	isocitrate dehydrogenase activity
EMQ_2837	COG0328	RNA-DNA hybrid ribonuclease activity
EMQ_2838	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EMQ_2839	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EMQ_2841	COG0405	Gamma-glutamyltransferase
EMQ_2844	COG0436	Aminotransferase
EMQ_2846	COG3956	TIGRFAM MazG family protein
EMQ_2847	COG1733	regulation of RNA biosynthetic process
EMQ_2849	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EMQ_2853	COG2207	Transcriptional regulator
EMQ_2854	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_2855	COG3118	belongs to the thioredoxin family
EMQ_2856	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EMQ_2857	COG2835	tetraacyldisaccharide 4'-kinase activity
EMQ_2859	COG1032	radical SAM domain protein
EMQ_2865	COG1596	polysaccharide export
EMQ_2866	COG3750	Belongs to the UPF0335 family
EMQ_2867	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EMQ_2870	COG0406	alpha-ribazole phosphatase activity
EMQ_2871	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EMQ_2872	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EMQ_2880	COG4988	ABC transporter
EMQ_2881	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EMQ_2883	COG0514	ATP-dependent DNA helicase (RecQ)
EMQ_2887	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EMQ_2889	COG0438	transferase activity, transferring glycosyl groups
EMQ_2892	COG0438	transferase activity, transferring glycosyl groups
EMQ_2894	COG2205	protein histidine kinase activity
EMQ_2901	COG1113	amino acid transport
EMQ_2902	COG2175	clavaminate synthase activity
EMQ_2907	COG1053	succinate dehydrogenase
EMQ_2909	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EMQ_2910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EMQ_2911	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EMQ_2917	COG0516	GMP reductase activity
EMQ_2917	COG0517	IMP dehydrogenase activity
EMQ_2918	COG1007	ATP synthesis coupled electron transport
EMQ_2921	COG0713	ATP synthesis coupled electron transport
EMQ_2922	COG0839	Belongs to the complex I subunit 6 family
EMQ_2923	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_2924	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EMQ_2925	COG1034	ATP synthesis coupled electron transport
EMQ_2927	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EMQ_2928	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_2928	COG0649	NAD binding
EMQ_2929	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_2930	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_2935	COG0740	serine-type endopeptidase activity
EMQ_2939	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EMQ_2940	COG1766	The M ring may be actively involved in energy transduction
EMQ_2941	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EMQ_2943	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EMQ_2944	COG2204	response regulator
EMQ_2945	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EMQ_2947	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EMQ_2948	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EMQ_2949	COG1137	ATPase activity
EMQ_2958	COG0667	Aldo Keto reductase
EMQ_2959	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EMQ_2963	COG0582	viral genome integration into host DNA
EMQ_2985	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EMQ_2986	COG1335	isochorismatase
EMQ_2987	COG1744	ABC transporter substrate-binding protein PnrA-like
EMQ_2988	COG3845	ABC transporter
EMQ_2990	COG1079	Belongs to the binding-protein-dependent transport system permease family
EMQ_2992	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EMQ_2992	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMQ_2993	COG1372	Participates in initiation and elongation during chromosome replication
EMQ_2993	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMQ_2995	COG2244	polysaccharide biosynthetic process
EMQ_2996	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EMQ_2997	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EMQ_2999	COG2351	hydroxyisourate hydrolase activity
EMQ_3002	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EMQ_3007	COG0583	DNA-binding transcription factor activity
EMQ_3011	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EMQ_3012	COG0402	S-adenosylhomocysteine deaminase activity
EMQ_3013	COG3293	Transposase
EMQ_3025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EMQ_3027	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EMQ_3029	COG0181	hydroxymethylbilane synthase activity
EMQ_3030	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EMQ_3035	COG0583	DNA-binding transcription factor activity
EMQ_3037	COG0004	ammonium transporteR
EMQ_3043	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EMQ_3044	COG0840	transmembrane signaling receptor activity
EMQ_3046	COG0643	Histidine kinase
EMQ_3046	COG2198	Histidine kinase
EMQ_3047	COG0835	chemotaxis
EMQ_3048	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EMQ_3049	COG2201	protein-glutamate methylesterase activity
EMQ_3050	COG0745	RESPONSE REGULATOR receiver
EMQ_3051	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EMQ_3053	COG0488	(ABC) transporter
EMQ_3054	COG0105	UTP biosynthetic process
EMQ_3058	COG2706	6-phosphogluconolactonase activity
EMQ_3059	COG0281	malic enzyme
EMQ_3061	COG0215	cysteine-tRNA ligase activity
EMQ_3064	COG5492	domain, Protein
EMQ_3064	COG3583	domain protein
EMQ_3064	COG1621	beta-fructofuranosidase activity
EMQ_3069	COG0446	pyridine nucleotide-disulphide oxidoreductase
EMQ_3069	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EMQ_3071	COG1760	l-serine dehydratase
EMQ_3072	COG4638	Rieske (2fe-2S)
EMQ_3075	COG0446	pyridine nucleotide-disulphide oxidoreductase
EMQ_3075	COG1902	pentaerythritol trinitrate reductase activity
EMQ_3076	COG0247	lactate metabolic process
EMQ_3076	COG2181	nitrate reductase activity
EMQ_3079	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EMQ_3080	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EMQ_3085	COG0583	DNA-binding transcription factor activity
EMQ_3092	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EMQ_3093	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EMQ_3093	COG3153	acetyltransferase
EMQ_3096	COG1012	belongs to the aldehyde dehydrogenase family
EMQ_3098	COG4175	Glycine betaine
EMQ_3100	COG0735	belongs to the Fur family
EMQ_3107	COG3588	fructose-bisphosphate aldolase
EMQ_3108	COG3961	Belongs to the TPP enzyme family
EMQ_3109	COG0247	lactate metabolic process
EMQ_3110	COG1139	Iron-sulfur cluster binding protein
EMQ_3118	COG0052	Belongs to the universal ribosomal protein uS2 family
EMQ_3119	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EMQ_3120	COG1381	Involved in DNA repair and RecF pathway recombination
EMQ_3123	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EMQ_3128	COG0649	NAD binding
EMQ_3129	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EMQ_3130	COG1183	phosphatidylcholine synthase activity
EMQ_3131	COG0688	phosphatidylethanolamine metabolic process
EMQ_3135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EMQ_3140	COG2884	Cell division ATP-binding protein ftsE
EMQ_3144	COG2081	HI0933 family
EMQ_3145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EMQ_3146	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EMQ_3148	COG0628	permease
EMQ_3149	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EMQ_3150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EMQ_3154	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EMQ_3155	COG1127	ABC transporter
EMQ_3156	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EMQ_3157	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EMQ_3162	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EMQ_3163	COG0583	DNA-binding transcription factor activity
EMQ_3164	COG4771	TonB-dependent receptor
EMQ_3167	COG0668	transmembrane transport
EMQ_3168	COG1714	RDD family
EMQ_3169	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EMQ_3170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EMQ_3171	COG0653	protein targeting
EMQ_3172	COG0217	transcriptional regulatory protein
EMQ_3174	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EMQ_3176	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EMQ_3177	COG0504	CTP synthase activity
EMQ_3180	COG0149	triose-phosphate isomerase activity
EMQ_3183	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EMQ_3184	COG3217	Mosc domain protein beta barrel domain protein
EMQ_3184	COG0633	Ferredoxin
EMQ_3185	COG0306	phosphate transporter
EMQ_3194	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EMQ_3195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EMQ_3196	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EMQ_3199	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EMQ_3201	COG0386	Belongs to the glutathione peroxidase family
EMQ_3202	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EMQ_3211	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EMQ_3212	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EMQ_3213	COG4206	TonB-dependent receptor
EMQ_3215	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EMQ_3216	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EMQ_3219	COG0742	ribosomal rna small subunit methyltransferase
EMQ_3220	COG1187	pseudouridine synthase activity
EMQ_3221	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EMQ_3222	COG0590	tRNA wobble adenosine to inosine editing
EMQ_3225	COG0523	cobalamin synthesis protein
EMQ_3228	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EMQ_3230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EMQ_3230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EMQ_3234	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EMQ_3235	COG2945	thiolester hydrolase activity
EMQ_3237	COG3394	polysaccharide catabolic process
EMQ_3238	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EMQ_3241	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EMQ_3242	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EMQ_3243	COG1253	flavin adenine dinucleotide binding
EMQ_3244	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EMQ_3245	COG4133	protoheme IX ABC transporter activity
EMQ_3246	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EMQ_3247	COG1126	abc transporter atp-binding protein
EMQ_3248	COG0765	amino acid transport
EMQ_3249	COG0583	DNA-binding transcription factor activity
EMQ_3251	COG0542	response to heat
EMQ_3253	COG0779	Required for maturation of 30S ribosomal subunits
EMQ_3256	COG5373	membrane
EMQ_3256	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EMQ_3257	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EMQ_3258	COG3293	Transposase
EMQ_3262	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EMQ_3265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EMQ_3267	COG1414	Transcriptional regulator
EMQ_3271	COG1032	radical SAM domain protein
EMQ_3274	COG1621	beta-fructofuranosidase activity
EMQ_3275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EMQ_3279	COG2217	Heavy metal translocating P-type atpase
EMQ_3282	COG1297	OPT oligopeptide transporter protein
EMQ_3283	COG1511	domain protein
EMQ_3283	COG3264	Mechanosensitive ion channel
EMQ_3284	COG1028	Short-chain dehydrogenase reductase Sdr
EMQ_3285	COG0612	Peptidase, M16
EMQ_3287	COG1116	anion transmembrane transporter activity
EMQ_3289	COG0756	dUTP diphosphatase activity
EMQ_3291	COG2226	methyltransferase
EMQ_3292	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EMQ_3293	COG0268	Binds directly to 16S ribosomal RNA
EMQ_P104	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EMQ_P112	COG2184	nucleotidyltransferase activity
EMQ_P133	COG1475	DNA binding
EMQ_P138	COG3831	ATPase activity
EMQ_P160	COG0431	NADPH-dependent FMN reductase
EMQ_P162	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EMQ_P164	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EMQ_P167	COG0659	secondary active sulfate transmembrane transporter activity
EMQ_P169	COG0789	Transcriptional regulator
EMQ_P209	COG4397	Mu-like prophage major head subunit gpT
EMQ_P223	COG2161	toxin-antitoxin pair type II binding
EMQ_P238	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EMQ_P308	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EMQ_P402	COG3041	Addiction module toxin RelE StbE family
EMQ_P403	COG3077	Addiction module antitoxin, RelB DinJ family
EMQ_P404	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS