locus-tag	class	description
WG31_00005	COG0424	maF-like protein
WG31_00020	COG1671	Belongs to the UPF0178 family
WG31_00030	COG2814	Major facilitator Superfamily
WG31_00040	COG2835	tetraacyldisaccharide 4'-kinase activity
WG31_00045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WG31_00055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WG31_00080	COG0778	Nitroreductase
WG31_00090	COG0456	acetyltransferase
WG31_00100	COG1570	exodeoxyribonuclease VII activity
WG31_00115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WG31_00120	COG1012	belongs to the aldehyde dehydrogenase family
WG31_00130	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WG31_00135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WG31_00145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WG31_00155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WG31_00160	COG1053	succinate dehydrogenase
WG31_00165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WG31_00180	COG0126	phosphoglycerate kinase activity
WG31_00190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WG31_00200	COG0156	8-amino-7-oxononanoate synthase activity
WG31_00210	COG0405	Gamma-glutamyltransferase
WG31_00230	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
WG31_00240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WG31_00260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WG31_00265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WG31_00275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WG31_00285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WG31_00290	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WG31_00295	COG0539	negative regulation of cytoplasmic translation
WG31_00305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WG31_00310	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WG31_00315	COG1420	regulation of RNA biosynthetic process
WG31_00320	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WG31_00355	COG0772	Belongs to the SEDS family
WG31_00360	COG0768	penicillin binding
WG31_00380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WG31_00385	COG1612	heme a metabolic process
WG31_00395	COG2814	Major facilitator Superfamily
WG31_00405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WG31_00410	COG1289	transmembrane transporter activity
WG31_00420	COG1573	uracil-dna glycosylase
WG31_00440	COG0670	Belongs to the BI1 family
WG31_00465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WG31_00480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WG31_00495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WG31_00515	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WG31_00535	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_00540	COG0586	Pfam SNARE associated Golgi protein
WG31_00550	COG0281	malic enzyme
WG31_00580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WG31_00585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WG31_00590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WG31_00595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WG31_00600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WG31_00605	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WG31_00610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WG31_00615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WG31_00630	COG1113	amino acid transport
WG31_00635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WG31_00640	COG4208	sulfate ABC transporter
WG31_00660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WG31_00665	COG2207	Transcriptional regulator
WG31_00670	COG4303	Ethanolamine ammonia lyase large subunit
WG31_00675	COG4302	ethanolamine ammonia-lyase activity
WG31_00680	COG1113	amino acid transport
WG31_00685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG31_00695	COG1538	Outer membrane efflux protein
WG31_00700	COG1278	Cold shock
WG31_00730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WG31_00735	COG0745	RESPONSE REGULATOR receiver
WG31_00760	COG0411	ABC transporter
WG31_00805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WG31_00865	COG4372	Transposase
WG31_00875	COG2963	transposase activity
WG31_00955	COG2983	Belongs to the UPF0260 family
WG31_00995	COG1566	PFAM secretion protein HlyD family protein
WG31_01015	COG1657	PFAM Prenyltransferase squalene oxidase
WG31_01020	COG1233	COG1233 Phytoene dehydrogenase and related
WG31_01025	COG1562	ergosterol biosynthetic process
WG31_01030	COG1562	ergosterol biosynthetic process
WG31_01035	COG1215	transferase activity, transferring glycosyl groups
WG31_01040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WG31_01050	COG0287	Prephenate dehydrogenase
WG31_01065	COG0450	alkyl hydroperoxide reductase
WG31_01070	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WG31_01080	COG2353	YceI-like domain
WG31_01090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WG31_01100	COG0488	(ABC) transporter
WG31_01120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WG31_01130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WG31_01135	COG0343	queuine tRNA-ribosyltransferase activity
WG31_01140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WG31_01150	COG1881	PFAM PEBP family protein
WG31_01165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WG31_01180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WG31_01210	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WG31_01215	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WG31_01230	COG0667	Aldo Keto reductase
WG31_01240	COG0556	nucleotide-excision repair
WG31_01250	COG0612	Peptidase, M16
WG31_01270	COG0463	Glycosyl transferase, family 2
WG31_01285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WG31_01295	COG0167	dihydroorotate dehydrogenase activity
WG31_01310	COG1692	metallophosphoesterase
WG31_01315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WG31_01340	COG0352	thiamine-phosphate diphosphorylase activity
WG31_01365	COG1509	lysine 2,3-aminomutase activity
WG31_01375	COG0024	Methionine aminopeptidase
WG31_01380	COG1686	Belongs to the peptidase S11 family
WG31_01385	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WG31_01400	COG2326	polyphosphate kinase activity
WG31_01405	COG1678	Uncharacterized ACR, COG1678
WG31_01410	COG1660	Displays ATPase and GTPase activities
WG31_01420	COG2205	protein histidine kinase activity
WG31_01425	COG0745	RESPONSE REGULATOR receiver
WG31_01430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WG31_01435	COG0443	Heat shock 70 kDa protein
WG31_01440	COG0484	heat shock protein binding
WG31_01445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WG31_01450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WG31_01455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WG31_01460	COG0138	bifunctional purine biosynthesis protein purh
WG31_01470	COG0697	spore germination
WG31_01480	COG0752	glycyl-tRNA synthetase alpha subunit
WG31_01490	COG1396	sequence-specific DNA binding
WG31_01495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WG31_01515	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WG31_01525	COG0598	Magnesium transport protein CorA
WG31_01530	COG0133	tryptophan synthase activity
WG31_01535	COG0159	tryptophan synthase activity
WG31_01540	COG0493	'glutamate synthase
WG31_01550	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
WG31_01555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WG31_01560	COG0745	RESPONSE REGULATOR receiver
WG31_01570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WG31_01595	COG1253	flavin adenine dinucleotide binding
WG31_01600	COG0604	alcohol dehydrogenase
WG31_01610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG31_01625	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_01630	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WG31_01635	COG3956	TIGRFAM MazG family protein
WG31_01645	COG0326	Molecular chaperone. Has ATPase activity
WG31_01770	COG0629	single-stranded DNA binding
WG31_01860	COG1783	phage Terminase large subunit
WG31_02090	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WG31_02115	COG0318	PFAM AMP-dependent synthetase and ligase
WG31_02135	COG4372	Transposase
WG31_02145	COG2963	transposase activity
WG31_02260	COG1396	sequence-specific DNA binding
WG31_02260	COG3800	Transcriptional regulator
WG31_02265	COG2079	MmgE PrpD family protein
WG31_02270	COG0372	Belongs to the citrate synthase family
WG31_02275	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WG31_02280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG31_02285	COG2814	Major facilitator Superfamily
WG31_02290	COG2319	Wd-40 repeat
WG31_02300	COG2309	aminopeptidase activity
WG31_02315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WG31_02325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WG31_02330	COG0193	aminoacyl-tRNA hydrolase activity
WG31_02335	COG0012	GTP binding
WG31_02340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WG31_02345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WG31_02355	COG0799	negative regulation of ribosome biogenesis
WG31_02360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WG31_02395	COG0247	lactate metabolic process
WG31_02400	COG1139	Iron-sulfur cluster binding protein
WG31_02410	COG0697	spore germination
WG31_02415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WG31_02420	COG0717	Belongs to the dCTP deaminase family
WG31_02435	COG3394	polysaccharide catabolic process
WG31_02455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WG31_02465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WG31_02470	COG1253	flavin adenine dinucleotide binding
WG31_02475	COG0741	lytic transglycosylase activity
WG31_02480	COG1573	uracil-dna glycosylase
WG31_02490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WG31_02530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WG31_02570	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_02575	COG0583	DNA-binding transcription factor activity
WG31_02580	COG0025	NhaP-type Na H and K H
WG31_02590	COG4771	TonB-dependent receptor
WG31_02600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WG31_02605	COG1120	ATPase activity
WG31_02610	COG3525	Glycosyl hydrolase, family 20, catalytic domain
WG31_02615	COG2971	BadF BadG BcrA BcrD
WG31_02620	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
WG31_02640	COG0415	Belongs to the DNA photolyase family
WG31_02645	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WG31_02675	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WG31_02760	COG1012	belongs to the aldehyde dehydrogenase family
WG31_02930	COG4626	Terminase
WG31_02930	COG1802	Transcriptional regulator
WG31_02960	COG0305	Participates in initiation and elongation during chromosome replication
WG31_03130	COG4774	siderophore transport
WG31_03400	COG1959	2 iron, 2 sulfur cluster binding
WG31_03405	COG4221	oxidoreductase activity
WG31_03410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WG31_03430	COG1607	acyl-coa hydrolase
WG31_03470	COG0306	phosphate transporter
WG31_03480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WG31_03485	COG0022	dehydrogenase e1 component
WG31_03495	COG0071	Belongs to the small heat shock protein (HSP20) family
WG31_03500	COG1252	NADH dehydrogenase
WG31_03510	COG0523	cobalamin synthesis protein
WG31_03520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WG31_03535	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
WG31_03540	COG0596	Alpha beta hydrolase
WG31_03555	COG1297	OPT oligopeptide transporter protein
WG31_03590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WG31_03600	COG0469	pyruvate kinase activity
WG31_03630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG31_03635	COG0492	ferredoxin-NADP+ reductase activity
WG31_03640	COG0538	isocitrate dehydrogenase activity
WG31_03675	COG4993	Dehydrogenase
WG31_03690	COG0481	GTPase activity
WG31_03695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WG31_03700	COG2813	Specifically methylates the guanine in position
WG31_03700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WG31_03705	COG0513	Belongs to the DEAD box helicase family
WG31_03730	COG1758	RNA polymerase activity
WG31_03735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WG31_03740	COG0736	holo-[acyl-carrier-protein] synthase activity
WG31_03745	COG0681	Belongs to the peptidase S26 family
WG31_03750	COG0571	ribonuclease III activity
WG31_03755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WG31_03760	COG0528	UMP kinase activity
WG31_03765	COG0233	cytoplasmic translational termination
WG31_03770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WG31_03780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WG31_03785	COG0750	zinc metalloprotease
WG31_03800	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG31_03805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WG31_03810	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG31_03815	COG3494	Protein of unknown function (DUF1009)
WG31_03820	COG0346	lactoylglutathione lyase activity
WG31_03830	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WG31_03835	COG0594	ribonuclease P activity
WG31_03840	COG0706	membrane insertase activity
WG31_03845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WG31_03850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WG31_03855	COG2171	N-acyltransferase activity
WG31_03860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WG31_03870	COG0101	tRNA pseudouridine synthase activity
WG31_03875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WG31_03880	COG0242	peptide deformylase activity
WG31_03895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WG31_03910	COG3217	Mosc domain protein beta barrel domain protein
WG31_03910	COG0633	Ferredoxin
WG31_03915	COG1137	ATPase activity
WG31_03930	COG0517	IMP dehydrogenase activity
WG31_03930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WG31_03940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WG31_03945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WG31_03950	COG4221	oxidoreductase activity
WG31_03955	COG0194	GDP metabolic process
WG31_03960	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WG31_03960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WG31_03965	COG2942	2-epimerase
WG31_03970	COG0305	Participates in initiation and elongation during chromosome replication
WG31_03975	COG3264	Mechanosensitive ion channel
WG31_03975	COG1196	nuclear chromosome segregation
WG31_03980	COG1127	ABC transporter
WG31_03985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WG31_04015	COG1113	amino acid transport
WG31_04025	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WG31_04025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WG31_04025	COG0506	proline dehydrogenase activity
WG31_04040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WG31_04070	COG2096	Adenosyltransferase
WG31_04085	COG0277	FAD linked oxidase domain protein
WG31_04095	COG0009	L-threonylcarbamoyladenylate synthase
WG31_04105	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WG31_04115	COG0656	L-ascorbic acid biosynthetic process
WG31_04125	COG1643	Atp-dependent helicase
WG31_04135	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WG31_04145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WG31_04150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WG31_04170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WG31_04175	COG0235	Class ii aldolase
WG31_04180	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
WG31_04185	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
WG31_04190	COG0196	riboflavin kinase activity
WG31_04195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WG31_04200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WG31_04210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WG31_04220	COG5006	permease, DMT superfamily
WG31_04225	COG0187	DNA topoisomerase II activity
WG31_04240	COG1959	2 iron, 2 sulfur cluster binding
WG31_04245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WG31_04250	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WG31_04250	COG2885	chlorophyll binding
WG31_04260	COG0793	Belongs to the peptidase S41A family
WG31_04265	COG0557	exoribonuclease II activity
WG31_04270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WG31_04275	COG0758	DNA mediated transformation
WG31_04280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WG31_04285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WG31_04290	COG0540	Belongs to the ATCase OTCase family
WG31_04295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WG31_04300	COG0658	competence protein
WG31_04300	COG2333	competence protein COMEC
WG31_04305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WG31_04310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WG31_04320	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG31_04340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WG31_04355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WG31_04390	COG3260	NADH ubiquinone oxidoreductase 20
WG31_04395	COG1183	phosphatidylcholine synthase activity
WG31_04400	COG0688	phosphatidylethanolamine metabolic process
WG31_04405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WG31_04415	COG2885	chlorophyll binding
WG31_04415	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WG31_04420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WG31_04430	COG4974	Belongs to the 'phage' integrase family
WG31_04435	COG0825	malonyl-CoA metabolic process
WG31_04440	COG1546	Belongs to the CinA family
WG31_04440	COG1058	Belongs to the CinA family
WG31_04445	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
WG31_04460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WG31_04465	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WG31_04470	COG0181	hydroxymethylbilane synthase activity
WG31_04480	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WG31_04485	COG0406	alpha-ribazole phosphatase activity
WG31_04495	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WG31_04515	COG0408	coproporphyrinogen oxidase activity
WG31_04520	COG2857	Cytochrome c1
WG31_04520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG31_04525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG31_04525	COG2857	Cytochrome c1
WG31_04530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
WG31_04550	COG0778	Nitroreductase
WG31_04630	COG1518	maintenance of DNA repeat elements
WG31_04810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WG31_04815	COG1902	pentaerythritol trinitrate reductase activity
WG31_04820	COG0640	Transcriptional regulator
WG31_04830	COG3591	Belongs to the peptidase S1B family
WG31_04835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WG31_04845	COG0019	diaminopimelate decarboxylase activity
WG31_04850	COG0165	Argininosuccinate lyase
WG31_04870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WG31_04875	COG0237	dephospho-CoA kinase activity
WG31_04880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WG31_04900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WG31_04910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WG31_04915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WG31_04925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WG31_04930	COG0248	Ppx GppA phosphatase
WG31_04945	COG1121	(ABC) transporter
WG31_04970	COG1289	transmembrane transporter activity
WG31_04975	COG1289	transmembrane transporter activity
WG31_04995	COG3088	subunit of a heme lyase
WG31_05000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WG31_05005	COG1138	Cytochrome C-type biogenesis protein
WG31_05010	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
WG31_05015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WG31_05050	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WG31_05080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WG31_05090	COG0477	Major facilitator Superfamily
WG31_05095	COG1322	Protein conserved in bacteria
WG31_05125	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WG31_05130	COG0081	regulation of translation
WG31_05135	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WG31_05140	COG0222	ribosome binding
WG31_05150	COG0085	RNA polymerase activity
WG31_05155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WG31_05160	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WG31_05165	COG0049	tRNA binding
WG31_05170	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WG31_05175	COG0051	transcription antitermination factor activity, RNA binding
WG31_05180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WG31_05185	COG0088	Forms part of the polypeptide exit tunnel
WG31_05190	COG0089	rRNA binding
WG31_05195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WG31_05200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WG31_05205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WG31_05210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WG31_05215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WG31_05220	COG0255	Belongs to the universal ribosomal protein uL29 family
WG31_05225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WG31_05230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WG31_05235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WG31_05240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WG31_05245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WG31_05250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WG31_05255	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WG31_05260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WG31_05265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WG31_05270	COG1841	ribosomal large subunit assembly
WG31_05275	COG0200	Binds to the 23S rRNA
WG31_05285	COG0563	adenylate kinase activity
WG31_05290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WG31_05295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WG31_05300	COG0202	RNA polymerase activity
WG31_05305	COG0203	ribosomal protein L17
WG31_05315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG31_05320	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WG31_05330	COG1538	Outer membrane efflux protein
WG31_05345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG31_05355	COG3237	CsbD-like
WG31_05360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WG31_05365	COG2189	Belongs to the N(4) N(6)-methyltransferase family
WG31_05390	COG0714	Associated with various cellular activities
WG31_05400	COG0617	tRNA 3'-terminal CCA addition
WG31_05405	COG1132	(ABC) transporter
WG31_05415	COG2814	Major facilitator Superfamily
WG31_05420	COG1051	belongs to the nudix hydrolase family
WG31_05430	COG0793	Belongs to the peptidase S41A family
WG31_05445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WG31_05450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WG31_05455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WG31_05460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WG31_05465	COG0505	Belongs to the CarA family
WG31_05475	COG0358	DNA primase activity
WG31_05480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WG31_05490	COG0360	Binds together with S18 to 16S ribosomal RNA
WG31_05495	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WG31_05500	COG0359	binds to the 23S rRNA
WG31_05505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WG31_05510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WG31_05540	COG1132	(ABC) transporter
WG31_05545	COG1802	Transcriptional regulator
WG31_05550	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WG31_05560	COG0850	regulation of cytokinetic process
WG31_05570	COG2081	HI0933 family
WG31_05575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WG31_05585	COG0457	Tetratricopeptide repeat
WG31_05585	COG0859	PFAM glycosyl transferase family 9
WG31_05595	COG3781	membrane
WG31_05600	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
WG31_05615	COG2884	Cell division ATP-binding protein ftsE
WG31_05640	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WG31_05645	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WG31_05650	COG2166	iron-sulfur cluster assembly
WG31_05665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WG31_05665	COG2010	Cytochrome c
WG31_05670	COG0246	Mannitol dehydrogenase
WG31_05675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WG31_05680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WG31_05685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WG31_05690	COG0072	phenylalanine-tRNA ligase activity
WG31_05690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WG31_05695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WG31_05700	COG0747	negative chemotaxis
WG31_05720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WG31_05735	COG0473	3-isopropylmalate dehydrogenase activity
WG31_05740	COG0006	proline dipeptidase activity
WG31_05745	COG2264	protein methyltransferase activity
WG31_05755	COG2003	Belongs to the UPF0758 family
WG31_05760	COG2003	Belongs to the UPF0758 family
WG31_05765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WG31_05790	COG0071	Belongs to the small heat shock protein (HSP20) family
WG31_05795	COG0254	rRNA binding
WG31_05800	COG1970	mechanosensitive ion channel activity
WG31_05810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WG31_05815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WG31_05825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WG31_05825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WG31_05830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WG31_05840	COG0142	geranyltranstransferase activity
WG31_05845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WG31_05850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WG31_05865	COG2062	phosphohistidine phosphatase, SixA
WG31_05870	COG0287	Prephenate dehydrogenase
WG31_05870	COG1605	Chorismate mutase
WG31_05900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WG31_05910	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WG31_05920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WG31_05930	COG0729	surface antigen
WG31_05950	COG0322	excinuclease ABC activity
WG31_05965	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WG31_05975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WG31_05980	COG0156	8-amino-7-oxononanoate synthase activity
WG31_05990	COG4106	trans-aconitate 2-methyltransferase activity
WG31_05990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WG31_05995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WG31_06000	COG0303	'Molybdopterin
WG31_06005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WG31_06015	COG0148	phosphopyruvate hydratase activity
WG31_06035	COG2022	thiamine diphosphate biosynthetic process
WG31_06050	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WG31_06055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WG31_06065	COG0385	Bile acid
WG31_06070	COG0076	glutamate decarboxylase activity
WG31_06085	COG0484	heat shock protein binding
WG31_06090	COG0271	Belongs to the BolA IbaG family
WG31_06100	COG0321	lipoyl(octanoyl) transferase activity
WG31_06120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WG31_06125	COG2226	methyltransferase
WG31_06150	COG2706	6-phosphogluconolactonase activity
WG31_06155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WG31_06160	COG0527	aspartate kinase activity
WG31_06165	COG2070	2-Nitropropane dioxygenase
WG31_06175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WG31_06180	COG0124	histidyl-tRNA synthetase
WG31_06185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WG31_06195	COG2890	protein-(glutamine-N5) methyltransferase activity
WG31_06215	COG1968	undecaprenyl-diphosphatase activity
WG31_06220	COG0531	amino acid
WG31_06235	COG2951	lytic endotransglycosylase activity
WG31_06240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WG31_06245	COG1686	Belongs to the peptidase S11 family
WG31_06250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WG31_06265	COG0084	hydrolase, TatD family'
WG31_06280	COG0259	pyridoxamine-phosphate oxidase activity
WG31_06285	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WG31_06290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WG31_06295	COG1764	response to oxidative stress
WG31_06300	COG0579	oxidoreductase
WG31_06310	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WG31_06315	COG0602	queuosine metabolic process
WG31_06320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WG31_06330	COG0175	sulfate reduction
WG31_06335	COG0175	sulfate reduction
WG31_06350	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WG31_06360	COG1519	Transferase
WG31_06365	COG1663	tetraacyldisaccharide 4'-kinase activity
WG31_06385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WG31_06390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WG31_06395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WG31_06405	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WG31_06435	COG1278	Cold shock
WG31_06440	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WG31_06445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WG31_06450	COG0077	Prephenate dehydratase
WG31_06450	COG1605	Chorismate mutase
WG31_06455	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WG31_06460	COG3474	cytochrome
WG31_06470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WG31_06475	COG0606	chelatase, subunit chli
WG31_06480	COG0626	cystathionine gamma-synthase activity
WG31_06485	COG2897	thiosulfate sulfurtransferase activity
WG31_06490	COG0628	permease
WG31_06505	COG0792	nuclease activity
WG31_06515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WG31_06520	COG0271	Belongs to the BolA IbaG family
WG31_06525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WG31_06530	COG0047	phosphoribosylformylglycinamidine synthase activity
WG31_06540	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WG31_06545	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WG31_06550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WG31_06555	COG0861	Integral membrane protein TerC family
WG31_06570	COG1546	Belongs to the CinA family
WG31_06585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WG31_06590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WG31_06595	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG31_06600	COG0508	dehydrogenase complex catalyzes the overall conversion of
WG31_06600	COG0022	dehydrogenase e1 component
WG31_06605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WG31_06610	COG0315	cyclic pyranopterin monophosphate synthase activity
WG31_06615	COG0134	indole-3-glycerol-phosphate synthase activity
WG31_06620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WG31_06630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WG31_06640	COG0149	triose-phosphate isomerase activity
WG31_06650	COG0504	CTP synthase activity
WG31_06655	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WG31_06660	COG0187	DNA topoisomerase II activity
WG31_06665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WG31_06670	COG0592	DNA-directed DNA polymerase activity
WG31_06675	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WG31_06680	COG0268	Binds directly to 16S ribosomal RNA
WG31_06685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WG31_06690	COG2226	methyltransferase
WG31_06695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WG31_06700	COG0756	dUTP diphosphatase activity
WG31_06705	COG1176	ABC-type spermidine putrescine transport system, permease component I
WG31_06710	COG1116	anion transmembrane transporter activity
WG31_06715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WG31_06720	COG0525	valine-tRNA ligase activity
WG31_06735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WG31_06760	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_06765	COG0456	acetyltransferase
WG31_06770	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WG31_06775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WG31_06780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WG31_06790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WG31_06795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WG31_06805	COG1349	DNA-binding transcription factor activity
WG31_06820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WG31_06825	COG4988	ABC transporter
WG31_06850	COG0784	Response regulator, receiver
WG31_06870	COG2824	Alkylphosphonate utilization operon protein PhnA
WG31_06875	COG0814	amino acid
WG31_06885	COG0384	phenazine biosynthesis protein PhzF
WG31_06925	COG4206	TonB-dependent receptor
WG31_06935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WG31_06960	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WG31_06970	COG2233	PERMEase
WG31_06975	COG2351	hydroxyisourate hydrolase activity
WG31_06990	COG2072	flavoprotein involved in K transport
WG31_07000	COG0402	S-adenosylhomocysteine deaminase activity
WG31_07035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WG31_07040	COG0842	Transport permease protein
WG31_07040	COG1129	ABC transporter
WG31_07045	COG0842	Transport permease protein
WG31_07060	COG1657	PFAM Prenyltransferase squalene oxidase
WG31_07080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WG31_07085	COG0753	catalase activity
WG31_07100	COG3459	Glycosyltransferase 36 associated
WG31_07135	COG4178	(ABC) transporter
WG31_07195	COG0477	Major facilitator Superfamily
WG31_07200	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
WG31_07210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG31_07215	COG1116	anion transmembrane transporter activity
WG31_07220	COG0864	Transcriptional regulator
WG31_07225	COG3665	Urea carboxylase-associated protein
WG31_07230	COG3665	Urea carboxylase-associated protein
WG31_07255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WG31_07265	COG1960	acyl-CoA dehydrogenase activity
WG31_07290	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WG31_07295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WG31_07300	COG4558	Periplasmic binding protein
WG31_07305	COG1321	iron dependent repressor
WG31_07310	COG1914	H( )-stimulated, divalent metal cation uptake system
WG31_07325	COG0848	biopolymer transport protein
WG31_07345	COG4372	Transposase
WG31_07355	COG2963	transposase activity
WG31_07360	COG4774	siderophore transport
WG31_07375	COG4774	siderophore transport
WG31_07385	COG1191	sigma factor activity
WG31_07390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WG31_07395	COG1116	anion transmembrane transporter activity
WG31_07400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WG31_07410	COG2175	clavaminate synthase activity
WG31_07490	COG2373	Large extracellular alpha-helical protein
WG31_07495	COG4953	penicillin-binding protein 1C
WG31_07605	COG1301	dicarboxylic acid transport
WG31_07610	COG0500	methyltransferase
WG31_07615	COG2999	glutathione oxidoreductase activity
WG31_07620	COG2814	Major facilitator Superfamily
WG31_07625	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
WG31_07675	COG0114	fumarate hydratase activity
WG31_07725	COG0628	permease
WG31_07745	COG0167	dihydroorotate dehydrogenase activity
WG31_07750	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WG31_07750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WG31_07750	COG0674	pyruvate-flavodoxin oxidoreductase activity
WG31_07750	COG1013	pyruvate-flavodoxin oxidoreductase activity
WG31_07755	COG0493	'glutamate synthase
WG31_07765	COG1971	Probably functions as a manganese efflux pump
WG31_07775	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WG31_07780	COG0746	molybdenum cofactor guanylyltransferase activity
WG31_07785	COG1763	Mo-molybdopterin cofactor biosynthetic process
WG31_07790	COG0303	'Molybdopterin
WG31_07795	COG3058	Necessary for formate dehydrogenase activity
WG31_07800	COG2864	formate dehydrogenase
WG31_07805	COG0437	4 iron, 4 sulfur cluster binding
WG31_07810	COG0243	molybdopterin cofactor binding
WG31_07810	COG3383	formate dehydrogenase (NAD+) activity
WG31_07820	COG0248	Ppx GppA phosphatase
WG31_07825	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WG31_07830	COG1940	carbohydrate kinase activity
WG31_07835	COG0425	Belongs to the sulfur carrier protein TusA family
WG31_07840	COG1722	exodeoxyribonuclease VII activity
WG31_07845	COG0142	geranyltranstransferase activity
WG31_07850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WG31_07855	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
WG31_07865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WG31_07870	COG0137	argininosuccinate synthase activity
WG31_07875	COG0545	Peptidyl-prolyl cis-trans isomerase
WG31_07885	COG0180	Tryptophanyl-tRNA synthetase
WG31_07900	COG0745	RESPONSE REGULATOR receiver
WG31_07915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WG31_07915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WG31_07925	COG0747	negative chemotaxis
WG31_07945	COG4608	Belongs to the ABC transporter superfamily
WG31_07950	COG2070	2-Nitropropane dioxygenase
WG31_07955	COG0671	phosphoesterase, PA-phosphatase related
WG31_07965	COG3511	phospholipase C
WG31_07980	COG1695	Transcriptional regulator
WG31_07990	COG1032	radical SAM domain protein
WG31_08005	COG0668	transmembrane transport
WG31_08020	COG1294	oxidase, subunit
WG31_08025	COG1271	oxidase subunit
WG31_08030	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WG31_08035	COG4988	ABC transporter
WG31_08040	COG3128	pkhd-type hydroxylase
WG31_08045	COG4774	siderophore transport
WG31_08060	COG0252	asparaginase activity
WG31_08070	COG2985	domain, Protein
WG31_08085	COG3293	Transposase
WG31_08090	COG0488	(ABC) transporter
WG31_08105	COG1064	alcohol dehydrogenase
WG31_08130	COG2814	Major facilitator Superfamily
WG31_08140	COG1902	pentaerythritol trinitrate reductase activity
WG31_08170	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WG31_08180	COG0583	DNA-binding transcription factor activity
WG31_08250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WG31_08290	COG0789	Transcriptional regulator
WG31_08335	COG0318	PFAM AMP-dependent synthetase and ligase
WG31_08345	COG0156	8-amino-7-oxononanoate synthase activity
WG31_08360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WG31_08385	COG0546	phosphoglycolate phosphatase activity
WG31_08390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WG31_08395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WG31_08410	COG0386	Belongs to the glutathione peroxidase family
WG31_08415	COG1136	(ABC) transporter
WG31_08425	COG0442	prolyl-tRNA aminoacylation
WG31_08435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
WG31_08445	COG1007	ATP synthesis coupled electron transport
WG31_08455	COG0713	ATP synthesis coupled electron transport
WG31_08465	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG31_08470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WG31_08475	COG1034	ATP synthesis coupled electron transport
WG31_08485	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WG31_08490	COG0649	NAD binding
WG31_08495	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG31_08500	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WG31_08515	COG0776	regulation of translation
WG31_08525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WG31_08530	COG0740	serine-type endopeptidase activity
WG31_08535	COG0544	peptidyl-prolyl cis-trans isomerase activity
WG31_08545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WG31_08545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WG31_08555	COG0513	Belongs to the DEAD box helicase family
WG31_08560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WG31_08565	COG0316	Belongs to the HesB IscA family
WG31_08570	COG2151	metal-sulfur cluster biosynthetic enzyme
WG31_08580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WG31_08585	COG0719	Fe-S assembly protein
WG31_08590	COG0396	ATPase activity
WG31_08595	COG0719	Fe-S assembly protein
WG31_08605	COG2733	membrane
WG31_08610	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WG31_08620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WG31_08625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WG31_08635	COG5265	(ABC) transporter
WG31_08645	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WG31_08650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WG31_08675	COG0612	Peptidase, M16
WG31_08680	COG0312	modulator of DNA gyrase
WG31_08695	COG0109	protoheme IX farnesyltransferase activity
WG31_08705	COG2226	methyltransferase
WG31_08725	COG0463	Glycosyl transferase, family 2
WG31_08730	COG1522	sequence-specific DNA binding
WG31_08735	COG0492	ferredoxin-NADP+ reductase activity
WG31_08740	COG0583	DNA-binding transcription factor activity
WG31_08745	COG4957	zinc ion binding
WG31_08750	COG0776	regulation of translation
WG31_08780	COG0776	regulation of translation
WG31_08785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WG31_08790	COG0416	fatty acid biosynthetic process
WG31_08795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WG31_08810	COG2205	protein histidine kinase activity
WG31_08815	COG0745	RESPONSE REGULATOR receiver
WG31_08820	COG1846	Transcriptional regulator
WG31_08830	COG0242	peptide deformylase activity
WG31_08835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WG31_08840	COG0473	3-isopropylmalate dehydrogenase activity
WG31_08845	COG0066	3-isopropylmalate dehydratase activity
WG31_08850	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WG31_08855	COG0335	large ribosomal subunit rRNA binding
WG31_08860	COG0336	Belongs to the RNA methyltransferase TrmD family
WG31_08865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WG31_08870	COG0228	four-way junction DNA binding
WG31_08895	COG0564	pseudouridine synthase activity
WG31_08900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WG31_08910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WG31_08920	COG3572	ergothioneine biosynthetic process
WG31_08925	COG2814	Major facilitator Superfamily
WG31_08930	COG1160	GTP binding
WG31_08955	COG0438	transferase activity, transferring glycosyl groups
WG31_08960	COG0367	asparagine synthase
WG31_08965	COG0354	folic acid binding
WG31_08970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WG31_08975	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WG31_08980	COG0659	secondary active sulfate transmembrane transporter activity
WG31_09000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WG31_09010	COG1051	belongs to the nudix hydrolase family
WG31_09015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WG31_09020	COG1923	regulation of RNA biosynthetic process
WG31_09025	COG2204	response regulator
WG31_09050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WG31_09050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
WG31_09055	COG0463	Glycosyl transferase, family 2
WG31_09100	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WG31_09110	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WG31_09125	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WG31_09130	COG0347	Belongs to the P(II) protein family
WG31_09140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WG31_09145	COG0586	Pfam SNARE associated Golgi protein
WG31_09150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WG31_09270	COG4386	tail sheath protein
WG31_09310	COG0616	signal peptide processing
WG31_09350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WG31_09475	COG0582	viral genome integration into host DNA
WG31_09485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WG31_09490	COG0483	inositol monophosphate 1-phosphatase activity
WG31_09495	COG1199	ATP-dependent helicase activity
WG31_09500	COG1278	Cold shock
WG31_09505	COG0412	Dienelactone hydrolase
WG31_09510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WG31_09515	COG0459	protein refolding
WG31_09570	COG0004	ammonium transporteR
WG31_09590	COG4974	Belongs to the 'phage' integrase family
WG31_09615	COG0494	nUDIX hydrolase
WG31_09635	COG0302	gtp cyclohydrolase
WG31_09645	COG0521	Mo-molybdopterin cofactor biosynthetic process
WG31_09675	COG1566	PFAM secretion protein HlyD family protein
WG31_09705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WG31_09710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WG31_09710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WG31_09715	COG0307	riboflavin synthase, alpha
WG31_09725	COG2857	Cytochrome c1
WG31_09725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG31_09730	COG2857	Cytochrome c1
WG31_09730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WG31_09735	COG0723	plastoquinol--plastocyanin reductase activity
WG31_09755	COG2252	PERMEase
WG31_09815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WG31_09820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WG31_09825	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WG31_09830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
WG31_09840	COG3750	Belongs to the UPF0335 family
WG31_09845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WG31_09860	COG2001	Belongs to the MraZ family
WG31_09865	COG0275	rRNA processing
WG31_09880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WG31_09890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WG31_09895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WG31_09905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WG31_09910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WG31_09915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WG31_09920	COG1181	Belongs to the D-alanine--D-alanine ligase family
WG31_09925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WG31_09930	COG0849	cell division
WG31_09940	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WG31_09945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WG31_09950	COG0497	DNA recombination
WG31_09955	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WG31_09960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WG31_09960	COG0574	Belongs to the PEP-utilizing enzyme family
WG31_09965	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WG31_09990	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
WG31_10005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WG31_10010	COG1335	isochorismatase
WG31_10030	COG2132	Multicopper oxidase
WG31_10040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WG31_10050	COG0028	Belongs to the TPP enzyme family
WG31_10055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WG31_10060	COG0560	Phosphoserine phosphatase
WG31_10075	COG0513	Belongs to the DEAD box helicase family
WG31_10095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WG31_10100	COG0531	amino acid
WG31_10105	COG0113	porphobilinogen synthase activity
WG31_10110	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WG31_10115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WG31_10120	COG1381	Involved in DNA repair and RecF pathway recombination
WG31_10125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WG31_10130	COG0052	Belongs to the universal ribosomal protein uS2 family
WG31_10150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WG31_10155	COG0587	DNA-directed DNA polymerase activity
WG31_10160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WG31_10165	COG0251	oxidation-reduction process
WG31_10190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WG31_10210	COG3161	chorismate lyase activity
WG31_10215	COG1032	radical SAM domain protein
WG31_10220	COG0105	UTP biosynthetic process
WG31_10225	COG0488	(ABC) transporter
WG31_10235	COG0745	RESPONSE REGULATOR receiver
WG31_10250	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WG31_10255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WG31_10290	COG0328	RNA-DNA hybrid ribonuclease activity
WG31_10295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WG31_10300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WG31_10350	COG1530	ribonuclease E activity
WG31_10355	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WG31_10360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WG31_10365	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WG31_10370	COG0424	maF-like protein
WG31_10380	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WG31_10410	COG0277	FAD linked oxidase domain protein
WG31_10445	COG1309	transcriptional regulator
WG31_10450	COG1252	NADH dehydrogenase
WG31_10455	COG1012	belongs to the aldehyde dehydrogenase family
WG31_10460	COG2814	Major facilitator Superfamily
WG31_10470	COG0431	NADPH-dependent FMN reductase
WG31_10480	COG0583	DNA-binding transcription factor activity
WG31_10490	COG1999	signal sequence binding
WG31_10535	COG0436	Aminotransferase
WG31_10540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WG31_10545	COG0384	phenazine biosynthesis protein PhzF
WG31_10550	COG1309	transcriptional regulator
WG31_10555	COG4221	oxidoreductase activity
WG31_10565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WG31_10570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WG31_10635	COG0583	DNA-binding transcription factor activity
WG31_10640	COG1289	transmembrane transporter activity
WG31_10665	COG4232	protein-disulfide reductase activity
WG31_10675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WG31_10680	COG0805	protein transport
WG31_10685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WG31_10690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WG31_10695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WG31_10705	COG0018	arginyl-trna synthetase
WG31_10710	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WG31_10715	COG0316	Belongs to the HesB IscA family
WG31_10720	COG0708	Exodeoxyribonuclease III
WG31_10740	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WG31_10745	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
WG31_10755	COG0535	radical SAM domain protein
WG31_10765	COG0740	serine-type endopeptidase activity
WG31_10775	COG0436	Aminotransferase
WG31_10785	COG1494	fructose-1,6-bisphosphatase
WG31_10795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WG31_10800	COG0564	pseudouridine synthase activity
WG31_10805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WG31_10810	COG1120	ATPase activity
WG31_10815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WG31_10820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WG31_10825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WG31_10825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WG31_10840	COG0477	Major facilitator Superfamily
WG31_10850	COG1294	oxidase, subunit
WG31_10855	COG1271	oxidase subunit
WG31_10875	COG1113	amino acid transport
WG31_10895	COG0135	phosphoribosylanthranilate isomerase activity
WG31_10900	COG0284	orotidine-5'-phosphate decarboxylase activity
WG31_10910	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WG31_10920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WG31_10925	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WG31_10935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WG31_10960	COG3145	DNA-N1-methyladenine dioxygenase activity
WG31_10970	COG3620	sequence-specific DNA binding
WG31_10980	COG2011	ABC-type metal ion transport system permease component
WG31_10985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WG31_10995	COG0277	FAD linked oxidase domain protein
WG31_11000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WG31_11000	COG1648	precorrin-2 dehydrogenase activity
WG31_11020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WG31_11025	COG0477	Major facilitator Superfamily
WG31_11030	COG1335	isochorismatase
WG31_11045	COG0071	Belongs to the small heat shock protein (HSP20) family
WG31_11090	COG1522	sequence-specific DNA binding
WG31_11095	COG2515	1-aminocyclopropane-1-carboxylate deaminase
WG31_11100	COG1522	sequence-specific DNA binding
WG31_11115	COG1846	Transcriptional regulator
WG31_11215	COG4372	Transposase
WG31_11240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WG31_11285	COG0848	biopolymer transport protein
WG31_11305	COG1301	dicarboxylic acid transport
WG31_11345	COG2814	Major facilitator Superfamily
WG31_11355	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WG31_11360	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
WG31_11375	COG0778	Nitroreductase
WG31_11380	COG1492	cobalamin metabolic process
WG31_11395	COG1797	cobyrinic acid a,c-diamide synthase activity
WG31_11420	COG1289	transmembrane transporter activity
WG31_11425	COG1584	GPR1 FUN34 yaaH family protein
WG31_11430	COG1024	Enoyl-CoA hydratase
WG31_11435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WG31_11440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WG31_11455	COG0735	belongs to the Fur family
WG31_11470	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
WG31_11490	COG0519	Catalyzes the synthesis of GMP from XMP
WG31_11490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WG31_11505	COG2814	Major facilitator Superfamily
WG31_11510	COG0739	heme binding
WG31_11510	COG1196	nuclear chromosome segregation
WG31_11510	COG0741	lytic transglycosylase activity
WG31_11530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WG31_11565	COG1742	UPF0060 membrane protein
WG31_11580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WG31_11595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WG31_11600	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WG31_11610	COG0363	glucosamine-6-phosphate deaminase activity
WG31_11615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WG31_11620	COG3265	gluconokinase activity
WG31_11655	COG3158	transport of potassium into the cell
WG31_11660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WG31_11680	COG0583	DNA-binding transcription factor activity
WG31_11700	COG0410	ABC transporter
WG31_11705	COG0411	ABC transporter
WG31_11715	COG0559	Belongs to the binding-protein-dependent transport system permease family
WG31_11725	COG0784	Response regulator, receiver
WG31_11725	COG2198	Histidine kinase
WG31_11725	COG5002	protein histidine kinase activity
WG31_11730	COG0745	RESPONSE REGULATOR receiver
WG31_11745	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WG31_11750	COG0830	nickel cation binding
WG31_11755	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
WG31_11760	COG0804	urea catabolic process
WG31_11765	COG0832	Belongs to the urease beta subunit family
WG31_11770	COG0831	urea catabolic process
WG31_11775	COG0829	nickel cation binding
WG31_11780	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
WG31_11785	COG3961	Belongs to the TPP enzyme family
WG31_11810	COG1393	Belongs to the ArsC family
WG31_11820	COG2818	Glycosylase
WG31_11825	COG0640	Transcriptional regulator
WG31_11830	COG0450	alkyl hydroperoxide reductase
WG31_11885	COG2271	Major facilitator Superfamily
WG31_11890	COG3473	Maleate cis-trans isomerase
WG31_11895	COG0596	Alpha beta hydrolase
WG31_11900	COG1335	isochorismatase
WG31_11905	COG2309	aminopeptidase activity
WG31_11910	COG2010	Cytochrome c
WG31_11910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WG31_11915	COG2080	2 iron, 2 sulfur cluster binding
WG31_11920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WG31_11925	COG1846	Transcriptional regulator
WG31_11970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WG31_11980	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WG31_12000	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WG31_12000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WG31_12005	COG0509	glycine decarboxylation via glycine cleavage system
WG31_12010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WG31_12015	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WG31_12020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
WG31_12030	COG0583	DNA-binding transcription factor activity
WG31_12040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WG31_12045	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WG31_12050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WG31_12065	COG1185	polyribonucleotide nucleotidyltransferase activity
WG31_12070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WG31_12075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WG31_12080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WG31_12085	COG1127	ABC transporter
WG31_12090	COG3008	intermembrane lipid transfer
WG31_12090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WG31_12125	COG2274	protein secretion by the type I secretion system
WG31_12135	COG0646	methionine synthase
WG31_12135	COG1410	methionine synthase
WG31_12150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WG31_12160	COG3008	intermembrane lipid transfer
WG31_12165	COG2995	paraquat-inducible protein a
WG31_12175	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WG31_12180	COG0463	Glycosyl transferase, family 2
WG31_12185	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WG31_12190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WG31_12195	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WG31_12200	COG0356	it plays a direct role in the translocation of protons across the membrane
WG31_12210	COG0552	protein localization to endoplasmic reticulum
WG31_12215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WG31_12220	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WG31_12225	COG0346	lactoylglutathione lyase activity
WG31_12235	COG0513	Belongs to the DEAD box helicase family
WG31_12250	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WG31_12255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WG31_12270	COG0704	Plays a role in the regulation of phosphate uptake
WG31_12275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WG31_12285	COG0573	inorganic phosphate transmembrane transporter activity
WG31_12290	COG0129	dihydroxy-acid dehydratase activity
WG31_12325	COG0489	protein tyrosine kinase activity
WG31_12340	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
WG31_12350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WG31_12350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WG31_12370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WG31_12375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WG31_12380	COG1522	sequence-specific DNA binding
WG31_12385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WG31_12390	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WG31_12405	COG0779	Required for maturation of 30S ribosomal subunits
WG31_12415	COG0542	response to heat
WG31_12430	COG0765	amino acid transport
WG31_12435	COG1126	abc transporter atp-binding protein
WG31_12445	COG4133	protoheme IX ABC transporter activity
WG31_12465	COG1295	ribonuclease BN
WG31_12475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WG31_12480	COG0511	ligase activity, forming carbon-carbon bonds
WG31_12485	COG0439	Biotin carboxylase
WG31_12490	COG2814	Major facilitator Superfamily
WG31_12495	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WG31_12545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WG31_12555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WG31_12560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WG31_12565	COG0154	amidase activity
WG31_12570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WG31_12580	COG1132	(ABC) transporter
WG31_12590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WG31_12595	COG1194	a g-specific adenine glycosylase
WG31_12620	COG0495	leucyl-tRNA aminoacylation
WG31_12695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WG31_12705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WG31_12715	COG0590	tRNA wobble adenosine to inosine editing
WG31_12720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WG31_12725	COG1187	pseudouridine synthase activity
WG31_12730	COG0742	ribosomal rna small subunit methyltransferase
WG31_12735	COG0629	single-stranded DNA binding
WG31_12745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WG31_12765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WG31_12770	COG0312	modulator of DNA gyrase
WG31_12775	COG0406	alpha-ribazole phosphatase activity
WG31_12795	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
WG31_12800	COG1091	dTDP-4-dehydrorhamnose reductase activity
WG31_12810	COG1674	ftsk spoiiie
WG31_12815	COG0564	pseudouridine synthase activity
WG31_12830	COG0482	sulfurtransferase activity
WG31_12840	COG1104	cysteine desulfurase activity
WG31_12850	COG2945	thiolester hydrolase activity
WG31_12860	COG0215	cysteine-tRNA ligase activity
WG31_12870	COG0285	dihydrofolate synthase activity
WG31_12875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WG31_12885	COG1074	ATP-dependent DNA helicase activity
WG31_12890	COG2887	Belongs to the helicase family. UvrD subfamily
WG31_12895	COG0802	atpase or kinase
WG31_12900	COG0745	RESPONSE REGULATOR receiver
WG31_12905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WG31_12915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WG31_12920	COG0037	tRNA processing
WG31_12930	COG2885	chlorophyll binding
WG31_12935	COG0823	Involved in the tonB-independent uptake of proteins
WG31_12955	COG0824	Thioesterase
WG31_12960	COG2255	four-way junction helicase activity
WG31_12965	COG0632	four-way junction helicase activity
WG31_12970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WG31_12975	COG0217	transcriptional regulatory protein
WG31_12980	COG0653	protein targeting
WG31_12985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WG31_12990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
WG31_13000	COG0668	transmembrane transport
WG31_13050	COG0776	regulation of translation
WG31_13070	COG1216	Glycosyl transferase, family 2
WG31_13085	COG0131	Imidazoleglycerol-phosphate dehydratase
WG31_13090	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WG31_13095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WG31_13100	COG0107	imidazoleglycerol-phosphate synthase activity
WG31_13105	COG0140	phosphoribosyl-ATP diphosphatase activity
WG31_13115	COG0778	Nitroreductase
WG31_13145	COG1475	DNA binding
WG31_13150	COG1192	Involved in chromosome partitioning
WG31_13155	COG0357	Ribosomal RNA small subunit methyltransferase G
WG31_13160	COG0445	tRNA wobble uridine modification
WG31_13165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WG31_13195	COG1611	Belongs to the LOG family
WG31_13200	COG2814	Major facilitator Superfamily
WG31_13215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WG31_13220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WG31_13290	COG3189	MarR family transcriptional regulator
WG31_13295	COG3256	nitric oxide reductase
WG31_13300	COG1017	nitric oxide dioxygenase activity
WG31_13300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WG31_13305	COG1959	2 iron, 2 sulfur cluster binding
WG31_13395	COG0583	DNA-binding transcription factor activity
WG31_13405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WG31_13430	COG2144	transferase activity, transferring acyl groups
WG31_13445	COG2072	flavoprotein involved in K transport
WG31_13455	COG1028	Short-chain dehydrogenase reductase Sdr
WG31_13460	COG0583	DNA-binding transcription factor activity
WG31_13480	COG3077	Addiction module antitoxin, RelB DinJ family
WG31_13485	COG2026	Addiction module toxin, RelE StbE family
WG31_13495	COG4716	Myosin-crossreactive antigen
WG31_13510	COG2801	Transposase and inactivated derivatives
WG31_13535	COG4974	Belongs to the 'phage' integrase family
WG31_13575	COG0583	DNA-binding transcription factor activity
WG31_13580	COG3293	Transposase
WG31_13595	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
WG31_13600	COG2072	flavoprotein involved in K transport
WG31_13605	COG0431	NADPH-dependent FMN reductase
WG31_13610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WG31_13625	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WG31_13635	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
WG31_13650	COG1012	belongs to the aldehyde dehydrogenase family
WG31_13655	COG1979	alcohol dehydrogenase
WG31_13660	COG1309	transcriptional regulator
WG31_13685	COG3189	MarR family transcriptional regulator
WG31_13715	COG2026	Addiction module toxin, RelE StbE family
WG31_13720	COG3077	Addiction module antitoxin, RelB DinJ family
WG31_13765	COG2072	flavoprotein involved in K transport
WG31_13815	COG0789	Transcriptional regulator
WG31_13820	COG1959	2 iron, 2 sulfur cluster binding
WG31_13875	COG0745	RESPONSE REGULATOR receiver
WG31_13880	COG0642	Histidine kinase
WG31_13890	COG2223	nitrite transmembrane transporter activity
WG31_13900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WG31_13900	COG2146	nitrite reductase [NAD(P)H] activity
WG31_13905	COG0243	molybdopterin cofactor binding
WG31_13920	COG2072	flavoprotein involved in K transport
WG31_13925	COG1012	belongs to the aldehyde dehydrogenase family
WG31_13935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WG31_13990	COG2963	transposase activity
WG31_14005	COG1294	oxidase, subunit
WG31_14010	COG1271	oxidase subunit
WG31_14035	COG2336	PFAM SpoVT AbrB
WG31_14040	COG2337	Toxic component of a toxin-antitoxin (TA) module
WG31_14105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WG31_14140	COG2337	Toxic component of a toxin-antitoxin (TA) module
WG31_14145	COG2336	PFAM SpoVT AbrB
WG31_14165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WG31_14175	COG4372	Transposase
WG31_14185	COG2963	transposase activity
WG31_14225	COG1475	DNA binding
WG31_14230	COG1192	Involved in chromosome partitioning
WG31_14240	COG1475	DNA binding
WG31_14380	COG4957	zinc ion binding
WG31_14400	COG1280	lysine exporter protein (LysE YggA)
WG31_14510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WG31_14525	COG2801	Transposase and inactivated derivatives
WG31_14555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WG31_14565	COG0302	gtp cyclohydrolase
WG31_14570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WG31_14575	COG0523	cobalamin synthesis protein
WG31_14585	COG0640	Transcriptional regulator
WG31_14660	COG4115	mRNA cleavage
WG31_14665	COG2161	toxin-antitoxin pair type II binding
WG31_14690	COG1487	ribonuclease activity
WG31_14750	COG4115	mRNA cleavage
WG31_14755	COG2161	toxin-antitoxin pair type II binding
WG31_14775	COG4957	zinc ion binding
WG31_14790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs